TWISTNB

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1ribosomal small subunit assembly (GO:0000028)5.32329741
2DNA deamination (GO:0045006)5.07819723
3maturation of SSU-rRNA (GO:0030490)4.67865675
4viral transcription (GO:0019083)4.55273821
5positive regulation of glycoprotein biosynthetic process (GO:0010560)4.52379205
6translational termination (GO:0006415)4.47349574
7ribosomal small subunit biogenesis (GO:0042274)4.38438107
8DNA strand elongation involved in DNA replication (GO:0006271)4.18930956
9ribosomal large subunit biogenesis (GO:0042273)4.18168411
10telomere maintenance via semi-conservative replication (GO:0032201)4.17452505
11establishment of protein localization to mitochondrial membrane (GO:0090151)4.16245100
12chaperone-mediated protein transport (GO:0072321)4.15739763
13DNA strand elongation (GO:0022616)4.01445963
14mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.98658059
15DNA replication initiation (GO:0006270)3.98564471
16SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.97882281
17translational elongation (GO:0006414)3.95162949
18ribonucleoprotein complex biogenesis (GO:0022613)3.93639927
19nucleobase biosynthetic process (GO:0046112)3.89640609
20cotranslational protein targeting to membrane (GO:0006613)3.87589926
21telomere maintenance via recombination (GO:0000722)3.85885234
22CENP-A containing nucleosome assembly (GO:0034080)3.85136551
23protein targeting to ER (GO:0045047)3.85048768
24mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.81591441
25mitochondrial respiratory chain complex I assembly (GO:0032981)3.81591441
26NADH dehydrogenase complex assembly (GO:0010257)3.81591441
27formation of translation preinitiation complex (GO:0001731)3.79892041
28purine nucleobase biosynthetic process (GO:0009113)3.79588627
29translational initiation (GO:0006413)3.79578890
30chromatin remodeling at centromere (GO:0031055)3.77459861
31replication fork processing (GO:0031297)3.65062657
32regulation of protein glycosylation (GO:0060049)3.64867805
33establishment of protein localization to endoplasmic reticulum (GO:0072599)3.64491224
34protein heterotetramerization (GO:0051290)3.64197249
35protein localization to endoplasmic reticulum (GO:0070972)3.63895945
36ribosome biogenesis (GO:0042254)3.63783473
37nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.62217110
38pseudouridine synthesis (GO:0001522)3.61627826
39mitotic recombination (GO:0006312)3.59982509
40kinetochore organization (GO:0051383)3.58133181
41spermatid nucleus differentiation (GO:0007289)3.57960041
42positive regulation of glycoprotein metabolic process (GO:1903020)3.56694694
43protein localization to kinetochore (GO:0034501)3.51632206
44mitochondrial respiratory chain complex assembly (GO:0033108)3.50061311
45ribosome assembly (GO:0042255)3.48505312
46* transcription from RNA polymerase I promoter (GO:0006360)3.48362151
47viral life cycle (GO:0019058)3.45633785
48protein complex biogenesis (GO:0070271)3.45609952
49DNA replication checkpoint (GO:0000076)3.43089100
50rRNA processing (GO:0006364)3.42648954
51telomere maintenance via telomere lengthening (GO:0010833)3.41717517
52ubiquinone biosynthetic process (GO:0006744)3.41576132
53DNA replication-independent nucleosome assembly (GO:0006336)3.39321913
54DNA replication-independent nucleosome organization (GO:0034724)3.39321913
55cellular protein complex disassembly (GO:0043624)3.39199799
56transcription initiation from RNA polymerase I promoter (GO:0006361)3.38599457
57DNA damage response, detection of DNA damage (GO:0042769)3.38367445
58DNA unwinding involved in DNA replication (GO:0006268)3.37411412
59proteasome assembly (GO:0043248)3.34200427
60rRNA metabolic process (GO:0016072)3.31168840
61regulation of helicase activity (GO:0051095)3.30728815
62kinetochore assembly (GO:0051382)3.30639987
63energy coupled proton transport, down electrochemical gradient (GO:0015985)3.24784157
64ATP synthesis coupled proton transport (GO:0015986)3.24784157
65IMP biosynthetic process (GO:0006188)3.24137298
66termination of RNA polymerase III transcription (GO:0006386)3.23580035
67transcription elongation from RNA polymerase III promoter (GO:0006385)3.23580035
68deoxyribonucleotide biosynthetic process (GO:0009263)3.21630060
69protein deneddylation (GO:0000338)3.21571156
70nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.17447903
71deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.17220541
72translation (GO:0006412)3.15814065
73spliceosomal snRNP assembly (GO:0000387)3.14456394
74telomere maintenance via telomerase (GO:0007004)3.13150142
75maturation of 5.8S rRNA (GO:0000460)3.12861494
76ubiquinone metabolic process (GO:0006743)3.11758632
77cell fate commitment involved in formation of primary germ layer (GO:0060795)3.10495514
78ncRNA 3-end processing (GO:0043628)3.10474752
79negative regulation of ligase activity (GO:0051352)3.08452189
80negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.08452189
81nucleotide-excision repair, DNA gap filling (GO:0006297)3.07403595
82mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.07077640
83regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.06872415
84histone exchange (GO:0043486)3.04558722
85negative regulation of execution phase of apoptosis (GO:1900118)3.04103125
86maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)3.03272423
87pyrimidine deoxyribonucleotide metabolic process (GO:0009219)3.02768405
88cellular component biogenesis (GO:0044085)3.01871928
89nuclear-transcribed mRNA catabolic process (GO:0000956)2.99882435
90mitotic nuclear envelope disassembly (GO:0007077)2.99792556
91protein complex disassembly (GO:0043241)2.98796247
922-deoxyribonucleotide biosynthetic process (GO:0009265)2.98437641
93deoxyribose phosphate biosynthetic process (GO:0046385)2.98437641
94negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)2.98225485
95somatic diversification of immunoglobulins involved in immune response (GO:0002208)2.97009421
96isotype switching (GO:0045190)2.97009421
97somatic recombination of immunoglobulin genes involved in immune response (GO:0002204)2.97009421
98transcription-coupled nucleotide-excision repair (GO:0006283)2.96990990
99protein localization to chromosome, centromeric region (GO:0071459)2.96559320
100mitotic metaphase plate congression (GO:0007080)2.95296361
101regulation of centriole replication (GO:0046599)2.94210979
102histone H2B ubiquitination (GO:0033523)2.94167495
103termination of RNA polymerase I transcription (GO:0006363)2.92070661
104folic acid-containing compound biosynthetic process (GO:0009396)2.91055494
105DNA-templated transcription, termination (GO:0006353)2.90836744
106transcription elongation from RNA polymerase I promoter (GO:0006362)2.90807357
107regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)2.90696451
108protein-cofactor linkage (GO:0018065)2.89779445
109regulation of mitotic spindle checkpoint (GO:1903504)2.89556917
110regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)2.89556917
111IMP metabolic process (GO:0046040)2.88693274
112mRNA catabolic process (GO:0006402)2.88160289
113positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)2.87279789
114macromolecular complex disassembly (GO:0032984)2.86417229
115regulation of nuclear cell cycle DNA replication (GO:0033262)2.86340926
116meiotic chromosome segregation (GO:0045132)2.85467866
117anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:02.85459168
118telomere maintenance (GO:0000723)2.85388051
119telomere organization (GO:0032200)2.84668825
120regulation of spindle checkpoint (GO:0090231)2.83685337
121positive regulation of ubiquitin-protein transferase activity (GO:0051443)2.82738525
122viral mRNA export from host cell nucleus (GO:0046784)2.81372089
123RNA catabolic process (GO:0006401)2.81136039
124exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 2.81100386
125rRNA modification (GO:0000154)2.81001449
126pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)2.80859613
127RNA-dependent DNA replication (GO:0006278)2.80314637
1287-methylguanosine RNA capping (GO:0009452)2.79529113
129RNA capping (GO:0036260)2.79529113
130G1/S transition of mitotic cell cycle (GO:0000082)2.79062220
131cell cycle G1/S phase transition (GO:0044843)2.79062220
132signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)2.78702453
133intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)2.78702453
134DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:002.78044352
135antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:2.77855027
136signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)2.77349760
137signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)2.77349760
138signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)2.77349760
139metaphase plate congression (GO:0051310)2.76693271
140establishment of integrated proviral latency (GO:0075713)2.76016536
141histone mRNA metabolic process (GO:0008334)2.74665468
142membrane disassembly (GO:0030397)2.73708627
143nuclear envelope disassembly (GO:0051081)2.73708627
1447-methylguanosine mRNA capping (GO:0006370)2.72924874
145regulation of double-strand break repair via homologous recombination (GO:0010569)2.71150729
146signal transduction involved in DNA integrity checkpoint (GO:0072401)2.70470614

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human8.01923442
2* MYC_18555785_ChIP-Seq_MESCs_Mouse4.30722040
3EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.54187850
4E2F4_17652178_ChIP-ChIP_JURKAT_Human3.42331411
5GABP_17652178_ChIP-ChIP_JURKAT_Human3.29238516
6KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.20800754
7EST1_17652178_ChIP-ChIP_JURKAT_Human3.10145415
8* JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.92900519
9ETS1_20019798_ChIP-Seq_JURKAT_Human2.89407045
10* MYC_18358816_ChIP-ChIP_MESCs_Mouse2.81107965
11* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.78061468
12MYC_19079543_ChIP-ChIP_MESCs_Mouse2.75553573
13FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.64843138
14FOXM1_23109430_ChIP-Seq_U2OS_Human2.61227218
15CREB1_15753290_ChIP-ChIP_HEK293T_Human2.57580493
16ELF1_17652178_ChIP-ChIP_JURKAT_Human2.56681946
17* VDR_23849224_ChIP-Seq_CD4+_Human2.52735522
18HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.40109932
19SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.34949383
20NELFA_20434984_ChIP-Seq_ESCs_Mouse2.27609329
21CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.25978055
22XRN2_22483619_ChIP-Seq_HELA_Human2.25477049
23FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.25374965
24RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.21157190
25NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.20789829
26E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.19773653
27FOXP3_21729870_ChIP-Seq_TREG_Human2.08810265
28DCP1A_22483619_ChIP-Seq_HELA_Human2.04081457
29HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.02308277
30SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.01669237
31TAL1_20887958_ChIP-Seq_HPC-7_Mouse2.00255073
32* E2F1_18555785_ChIP-Seq_MESCs_Mouse1.99787509
33NOTCH1_21737748_ChIP-Seq_TLL_Human1.99589082
34ELK1_19687146_ChIP-ChIP_HELA_Human1.96429636
35AR_21909140_ChIP-Seq_LNCAP_Human1.92439766
36* FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.89830237
37PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.88952019
38E2F1_21310950_ChIP-Seq_MCF-7_Human1.88180470
39EGR1_19374776_ChIP-ChIP_THP-1_Human1.87862266
40HOXB4_20404135_ChIP-ChIP_EML_Mouse1.87084708
41GABP_19822575_ChIP-Seq_HepG2_Human1.85374154
42FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.80810639
43TTF2_22483619_ChIP-Seq_HELA_Human1.79065356
44* MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.75323193
45MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.74349523
46GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.72350513
47IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.71432624
48FUS_26573619_Chip-Seq_HEK293_Human1.70660633
49MYCN_18555785_ChIP-Seq_MESCs_Mouse1.68935132
50SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.68176409
51THAP11_20581084_ChIP-Seq_MESCs_Mouse1.65697655
52* ERG_20887958_ChIP-Seq_HPC-7_Mouse1.64219578
53* SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.61537055
54EWS_26573619_Chip-Seq_HEK293_Human1.61092140
55SRF_21415370_ChIP-Seq_HL-1_Mouse1.60490649
56CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.58926673
57POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.56423580
58YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.52614810
59CIITA_25753668_ChIP-Seq_RAJI_Human1.51183533
60BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.49941449
61ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.49499732
62ZFX_18555785_ChIP-Seq_MESCs_Mouse1.49006409
63IRF8_22096565_ChIP-ChIP_GC-B_Human1.46874349
64SPI1_23547873_ChIP-Seq_NB4_Human1.44270770
65NANOG_18555785_ChIP-Seq_MESCs_Mouse1.42980150
66YY1_21170310_ChIP-Seq_MESCs_Mouse1.42874436
67SALL1_21062744_ChIP-ChIP_HESCs_Human1.42757096
68MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.42096151
69ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.39435692
70MYC_22102868_ChIP-Seq_BL_Human1.39359071
71KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.34796684
72VDR_22108803_ChIP-Seq_LS180_Human1.30838611
73KDM5A_27292631_Chip-Seq_BREAST_Human1.30609447
74MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.27087955
75IRF8_21731497_ChIP-ChIP_J774_Mouse1.25095047
76GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.24468391
77ZNF274_21170338_ChIP-Seq_K562_Hela1.20723276
78POU3F2_20337985_ChIP-ChIP_501MEL_Human1.19574896
79FLI1_27457419_Chip-Seq_LIVER_Mouse1.14877421
80TFEB_21752829_ChIP-Seq_HELA_Human1.13726749
81MYC_18940864_ChIP-ChIP_HL60_Human1.12875075
82HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.11801413
83PADI4_21655091_ChIP-ChIP_MCF-7_Human1.10493758
84MYB_21317192_ChIP-Seq_ERMYB_Mouse1.10392754
85STAT4_19710469_ChIP-ChIP_TH1__Mouse1.08273605
86E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.05891295
87CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.04431558
88PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.03560538
89ELK1_22589737_ChIP-Seq_MCF10A_Human1.02761295
90* STAT3_1855785_ChIP-Seq_MESCs_Mouse1.02434046
91SCL_19346495_ChIP-Seq_HPC-7_Human1.01789844
92TP63_19390658_ChIP-ChIP_HaCaT_Human1.01304467
93RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.00438216
94CEBPB_23403033_ChIP-Seq_LIVER_Mouse0.99547400
95IGF1R_20145208_ChIP-Seq_DFB_Human0.99525248
96POU5F1_18358816_ChIP-ChIP_MESCs_Mouse0.98881057
97* ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.97821953
98RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse0.97433577
99SREBP1_19666523_ChIP-Seq_LIVER_Mouse0.96659385
100EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.94808114
101BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.94459890
102CEBPB_24764292_ChIP-Seq_MC3T3_Mouse0.94087822
103MYB_26560356_Chip-Seq_TH1_Human0.93984267
104HNF4A_19761587_ChIP-ChIP_CACO-2_Human0.93313078
105KLF4_18555785_ChIP-Seq_MESCs_Mouse0.93075752
106ELF5_23300383_ChIP-Seq_T47D_Human0.92925909
107MYB_26560356_Chip-Seq_TH2_Human0.92188325
108EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human0.91833034
109* SOX2_18555785_ChIP-Seq_MESCs_Mouse0.90101855
110CEBPD_23245923_ChIP-Seq_MEFs_Mouse0.89928002
111CCND1_20090754_ChIP-ChIP_RETINA_Mouse0.89279624
112CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.86375970
113VDR_21846776_ChIP-Seq_THP-1_Human0.85364396
114NANOG_16153702_ChIP-ChIP_HESCs_Human0.83290739
115FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.83227218
116TP53_22573176_ChIP-Seq_HFKS_Human0.82923993
117BP1_19119308_ChIP-ChIP_Hs578T_Human0.82872557
118RUNX1_22412390_ChIP-Seq_EML_Mouse0.81822658
119KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.81007121
120RBPJ_22232070_ChIP-Seq_NCS_Mouse0.80153520
121POU5F1_16153702_ChIP-ChIP_HESCs_Human0.79068505
122MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.78673435
123DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.78647267
124* SMAD1_18555785_ChIP-Seq_MESCs_Mouse0.78631682
125CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.77852976
126IRF1_19129219_ChIP-ChIP_H3396_Human0.77487994
127PCGF2_27294783_Chip-Seq_ESCs_Mouse0.77381489
128SOX2_16153702_ChIP-ChIP_HESCs_Human0.77139365
129PRDM5_23873026_ChIP-Seq_MEFs_Mouse0.76855278
130SOX17_20123909_ChIP-Seq_XEN_Mouse0.75347313
131TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.72384409
132SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.72000404

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching4.68099507
2MP0010094_abnormal_chromosome_stability3.93228984
3MP0008057_abnormal_DNA_replication3.91677769
4MP0004957_abnormal_blastocyst_morpholog3.74685287
5MP0003111_abnormal_nucleus_morphology3.50917181
6MP0003077_abnormal_cell_cycle3.36201770
7MP0002396_abnormal_hematopoietic_system3.12981152
8MP0008058_abnormal_DNA_repair2.95232277
9MP0008007_abnormal_cellular_replicative2.86772147
10MP0003763_abnormal_thymus_physiology2.49731627
11MP0001835_abnormal_antigen_presentation2.46930923
12MP0001529_abnormal_vocalization2.45410993
13MP0005671_abnormal_response_to2.25974297
14MP0000490_abnormal_crypts_of2.23653650
15MP0008932_abnormal_embryonic_tissue2.09472239
16MP0009333_abnormal_splenocyte_physiolog1.93099998
17MP0009379_abnormal_foot_pigmentation1.90193436
18MP0003786_premature_aging1.83582070
19MP0009785_altered_susceptibility_to1.82697654
20MP0010352_gastrointestinal_tract_polyps1.82202032
21MP0006035_abnormal_mitochondrial_morpho1.80976524
22MP0002398_abnormal_bone_marrow1.80276953
23MP0005397_hematopoietic_system_phenotyp1.78119018
24MP0001545_abnormal_hematopoietic_system1.78119018
25MP0004808_abnormal_hematopoietic_stem1.77411181
26MP0000372_irregular_coat_pigmentation1.70581746
27MP0001853_heart_inflammation1.69055119
28MP0005075_abnormal_melanosome_morpholog1.68109550
29MP0006072_abnormal_retinal_apoptosis1.66678881
30MP0005253_abnormal_eye_physiology1.62355440
31MP0001800_abnormal_humoral_immune1.58388197
32MP0000685_abnormal_immune_system1.57889938
33MP0000350_abnormal_cell_proliferation1.57212720
34MP0002722_abnormal_immune_system1.56639492
35MP0000689_abnormal_spleen_morphology1.54383208
36MP0005174_abnormal_tail_pigmentation1.54184559
37MP0001727_abnormal_embryo_implantation1.52959940
38MP0002160_abnormal_reproductive_system1.50938596
39MP0000703_abnormal_thymus_morphology1.50790465
40MP0002019_abnormal_tumor_incidence1.49982506
41MP0002420_abnormal_adaptive_immunity1.49856256
42MP0003724_increased_susceptibility_to1.49153685
43MP0006292_abnormal_olfactory_placode1.48991140
44MP0001819_abnormal_immune_cell1.48797761
45MP0003890_abnormal_embryonic-extraembry1.48333035
46MP0001730_embryonic_growth_arrest1.48292108
47MP0002452_abnormal_antigen_presenting1.48186605
48MP0001851_eye_inflammation1.46414732
49MP0002723_abnormal_immune_serum1.46241539
50MP0000716_abnormal_immune_system1.45291311
51MP0003436_decreased_susceptibility_to1.45191407
52MP0005000_abnormal_immune_tolerance1.44581376
53MP0005025_abnormal_response_to1.43374637
54MP0002429_abnormal_blood_cell1.42983297
55MP0003123_paternal_imprinting1.42548917
56MP0003186_abnormal_redox_activity1.40948326
57MP0000313_abnormal_cell_death1.40398432
58MP0008877_abnormal_DNA_methylation1.39681564
59MP0002006_tumorigenesis1.36149781
60MP0002405_respiratory_system_inflammati1.32549181
61MP0002163_abnormal_gland_morphology1.31944333
62MP0003646_muscle_fatigue1.30096248
63MP0002166_altered_tumor_susceptibility1.29902142
64MP0010307_abnormal_tumor_latency1.29811987
65MP0006054_spinal_hemorrhage1.29601015
66MP0003195_calcinosis1.29132347
67MP0002277_abnormal_respiratory_mucosa1.29124365
68MP0002095_abnormal_skin_pigmentation1.26916919
69MP0001929_abnormal_gametogenesis1.25969025
70MP0010386_abnormal_urinary_bladder1.25779799
71MP0002148_abnormal_hypersensitivity_rea1.24984434
72MP0003806_abnormal_nucleotide_metabolis1.23610107
73MP0004147_increased_porphyrin_level1.23332379
74MP0009697_abnormal_copulation1.23074619
75MP0005395_other_phenotype1.22793075
76MP0003718_maternal_effect1.22031468
77MP0003567_abnormal_fetal_cardiomyocyte1.21513646
78MP0003937_abnormal_limbs/digits/tail_de1.21303593
79MP0005197_abnormal_uvea_morphology1.20460445
80MP0001873_stomach_inflammation1.19499905
81MP0005408_hypopigmentation1.18295133
82MP0010155_abnormal_intestine_physiology1.17237182
83MP0008995_early_reproductive_senescence1.16755285
84MP0002132_abnormal_respiratory_system1.16511940
85MP0002419_abnormal_innate_immunity1.16048468
86MP0000858_altered_metastatic_potential1.15367442
87MP0002933_joint_inflammation1.11914801
88MP0000653_abnormal_sex_gland1.07995489
89MP0008789_abnormal_olfactory_epithelium1.07861086
90MP0005379_endocrine/exocrine_gland_phen1.06472458
91MP0002080_prenatal_lethality1.05550728
92MP0001697_abnormal_embryo_size1.04761923
93MP0005380_embryogenesis_phenotype1.03693390
94MP0001672_abnormal_embryogenesis/_devel1.03693390
95MP0001191_abnormal_skin_condition1.03199375
96MP0003136_yellow_coat_color1.02656865
97MP0004142_abnormal_muscle_tone1.02139714
98MP0005389_reproductive_system_phenotype1.00584509
99MP0005464_abnormal_platelet_physiology0.97481983
100MP0005391_vision/eye_phenotype0.95348002
101MP0002837_dystrophic_cardiac_calcinosis0.94990585
102MP0001790_abnormal_immune_system0.94640160
103MP0005387_immune_system_phenotype0.94640160
104MP0000647_abnormal_sebaceous_gland0.94070934
105MP0005084_abnormal_gallbladder_morpholo0.93210632
106MP0003984_embryonic_growth_retardation0.92849387
107MP0001845_abnormal_inflammatory_respons0.91710251
108MP0002088_abnormal_embryonic_growth/wei0.89341238
109MP0001905_abnormal_dopamine_level0.89235268
110MP0003011_delayed_dark_adaptation0.88701667
111MP0000465_gastrointestinal_hemorrhage0.87462049
112MP0002086_abnormal_extraembryonic_tissu0.85188002
113MP0003941_abnormal_skin_development0.84390896
114MP0001188_hyperpigmentation0.83704874
115MP0008875_abnormal_xenobiotic_pharmacok0.83082893
116MP0002009_preneoplasia0.81408013
117MP0008873_increased_physiological_sensi0.81316857
118MP0000015_abnormal_ear_pigmentation0.80714138
119MP0003315_abnormal_perineum_morphology0.80254739
120MP0002210_abnormal_sex_determination0.79799198
121MP0001324_abnormal_eye_pigmentation0.78996873
122MP0000631_abnormal_neuroendocrine_gland0.78755321
123MP0002102_abnormal_ear_morphology0.78444632
124MP0000358_abnormal_cell_content/0.77331087
125MP0001119_abnormal_female_reproductive0.76424554
126MP0001293_anophthalmia0.75149308
127MP0002085_abnormal_embryonic_tissue0.74721275
128MP0005595_abnormal_vascular_smooth0.72918460
129MP0003943_abnormal_hepatobiliary_system0.72429577
130MP0002877_abnormal_melanocyte_morpholog0.72288849
131MP0002938_white_spotting0.71815837
132MP0008469_abnormal_protein_level0.70795259
133MP0002234_abnormal_pharynx_morphology0.70657598
134MP0001145_abnormal_male_reproductive0.70489863
135MP0003866_abnormal_defecation0.70251908
136MP0001764_abnormal_homeostasis0.69740618
137MP0006082_CNS_inflammation0.69462996
138MP0001286_abnormal_eye_development0.69022108
139MP0002075_abnormal_coat/hair_pigmentati0.68731096
140MP0000477_abnormal_intestine_morphology0.67258167
141MP0003448_altered_tumor_morphology0.67231924
142MP0003699_abnormal_female_reproductive0.67090654
143MP0005187_abnormal_penis_morphology0.66574876
144MP0006036_abnormal_mitochondrial_physio0.66563824
145MP0003828_pulmonary_edema0.66338606
146MP0002697_abnormal_eye_size0.66076864
147MP0002084_abnormal_developmental_patter0.64253620
148MP0003755_abnormal_palate_morphology0.64026857
149MP0009250_abnormal_appendicular_skeleto0.62802971
150MP0004197_abnormal_fetal_growth/weight/0.62351402
151MP0001881_abnormal_mammary_gland0.62296470

Predicted human phenotypes

RankGene SetZ-score
1Reticulocytopenia (HP:0001896)4.97932739
2Abnormality of cells of the erythroid lineage (HP:0012130)4.92217508
3Abnormal number of erythroid precursors (HP:0012131)4.87614357
4Acute necrotizing encephalopathy (HP:0006965)4.56417104
5Birth length less than 3rd percentile (HP:0003561)4.08450282
6Acute encephalopathy (HP:0006846)4.00833283
7Aplastic anemia (HP:0001915)3.98255772
8Abnormal mitochondria in muscle tissue (HP:0008316)3.96521979
9Progressive macrocephaly (HP:0004481)3.88401319
10Recurrent gram-negative bacterial infections (HP:0005420)3.75432010
11Pallor (HP:0000980)3.60988980
12Mitochondrial inheritance (HP:0001427)3.60032585
13Periodontitis (HP:0000704)3.55740612
14Increased CSF lactate (HP:0002490)3.54267988
15Oral leukoplakia (HP:0002745)3.36979329
16Macrocytic anemia (HP:0001972)3.26008435
17Chromsome breakage (HP:0040012)3.14598143
18Sparse scalp hair (HP:0002209)3.14300270
19Lipid accumulation in hepatocytes (HP:0006561)3.14257926
20Colon cancer (HP:0003003)3.11941660
21Abnormality of chromosome stability (HP:0003220)3.09684448
22Thrombocytosis (HP:0001894)3.07708930
23Cerebral edema (HP:0002181)3.07378261
2411 pairs of ribs (HP:0000878)3.06750502
25Deep philtrum (HP:0002002)3.05056147
26IgM deficiency (HP:0002850)3.00530636
27Type I transferrin isoform profile (HP:0003642)2.94978924
28Agnosia (HP:0010524)2.88656731
29Hepatocellular necrosis (HP:0001404)2.88468727
30Nasal speech (HP:0001611)2.81206749
31Reduced antithrombin III activity (HP:0001976)2.80018631
32Respiratory insufficiency due to defective ciliary clearance (HP:0200073)2.77404360
33Chronic bronchitis (HP:0004469)2.74897389
34Pancytopenia (HP:0001876)2.67105831
35Chromosomal breakage induced by crosslinking agents (HP:0003221)2.66862373
36Rough bone trabeculation (HP:0100670)2.63115837
37Petechiae (HP:0000967)2.60347819
38Selective tooth agenesis (HP:0001592)2.57697458
39Abnormality of the preputium (HP:0100587)2.56970391
40Myelodysplasia (HP:0002863)2.55139568
41Maternal diabetes (HP:0009800)2.55040300
42Hepatic necrosis (HP:0002605)2.54058111
43Premature graying of hair (HP:0002216)2.52231018
44Renal Fanconi syndrome (HP:0001994)2.50834379
45Lymphoma (HP:0002665)2.50538427
46Abnormality of the anterior horn cell (HP:0006802)2.48379892
47Degeneration of anterior horn cells (HP:0002398)2.48379892
48Abnormality of the heme biosynthetic pathway (HP:0010472)2.47753947
49Carpal bone hypoplasia (HP:0001498)2.46190776
50Type 2 muscle fiber atrophy (HP:0003554)2.44165985
51Muscle fiber atrophy (HP:0100295)2.42720987
52Absent thumb (HP:0009777)2.42504287
53Abnormality of DNA repair (HP:0003254)2.40485888
54IgG deficiency (HP:0004315)2.39894700
55Esophageal atresia (HP:0002032)2.38590319
56Entropion (HP:0000621)2.37387629
57Microvesicular hepatic steatosis (HP:0001414)2.35003444
58Microretrognathia (HP:0000308)2.32961604
59Small intestinal stenosis (HP:0012848)2.30579562
60Duodenal stenosis (HP:0100867)2.30579562
61Poor head control (HP:0002421)2.30040191
62Abnormality of the labia minora (HP:0012880)2.28646341
63Decreased activity of mitochondrial respiratory chain (HP:0008972)2.28181239
64Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.28181239
65Optic disc pallor (HP:0000543)2.27308634
66Aplasia/hypoplasia of the uterus (HP:0008684)2.26907639
67Bone marrow hypocellularity (HP:0005528)2.25658858
68Meckel diverticulum (HP:0002245)2.25636931
69Abnormality of T cells (HP:0002843)2.25205527
70Autoimmune hemolytic anemia (HP:0001890)2.24812853
71Recurrent abscess formation (HP:0002722)2.24129612
72Breast hypoplasia (HP:0003187)2.22571424
73Amaurosis fugax (HP:0100576)2.22060799
743-Methylglutaconic aciduria (HP:0003535)2.21501386
75Poikiloderma (HP:0001029)2.21257774
76T lymphocytopenia (HP:0005403)2.15523822
77Cellular immunodeficiency (HP:0005374)2.14844558
78Pulmonary fibrosis (HP:0002206)2.14747080
79Abnormality of the ileum (HP:0001549)2.14683473
80Abnormality of methionine metabolism (HP:0010901)2.13219933
81Abnormality of midbrain morphology (HP:0002418)2.13181642
82Molar tooth sign on MRI (HP:0002419)2.13181642
83Elevated erythrocyte sedimentation rate (HP:0003565)2.12159712
84Cerebellar dysplasia (HP:0007033)2.11753484
85Leukodystrophy (HP:0002415)2.11024857
86Recurrent bronchitis (HP:0002837)2.09709050
87Abnormality of T cell physiology (HP:0011840)2.08399782
88Severe combined immunodeficiency (HP:0004430)2.07460265
89Abnormal spermatogenesis (HP:0008669)2.06987131
90Abnormality of the intervertebral disk (HP:0005108)2.06563115
91Abnormality of the renal collecting system (HP:0004742)2.05829287
92Lactic acidosis (HP:0003128)2.05473348
93Cortical visual impairment (HP:0100704)2.04332099
94Septo-optic dysplasia (HP:0100842)2.04188830
95Medulloblastoma (HP:0002885)2.04157592
96Increased hepatocellular lipid droplets (HP:0006565)2.03291234
97Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.02810732
98Abnormal protein N-linked glycosylation (HP:0012347)2.02810732
99Abnormal protein glycosylation (HP:0012346)2.02810732
100Abnormal glycosylation (HP:0012345)2.02810732
101Abnormal trabecular bone morphology (HP:0100671)2.02063991
102Leukocytosis (HP:0001974)2.01064838
103Abnormality of T cell number (HP:0011839)2.01059006
104Abnormality of the duodenum (HP:0002246)2.00808010
105Combined immunodeficiency (HP:0005387)1.99893345
106Respiratory difficulties (HP:0002880)1.99714523
107Acute myeloid leukemia (HP:0004808)1.99502490
108Abnormality of the pons (HP:0007361)1.98945890
109Aplasia/Hypoplasia of the uvula (HP:0010293)1.98881380
110Cleft eyelid (HP:0000625)1.98607085
111Respiratory failure (HP:0002878)1.98371206
112Cerebral hypomyelination (HP:0006808)1.97949294
113Increased serum pyruvate (HP:0003542)1.96616095
114Gastrointestinal atresia (HP:0002589)1.96469379
115Sparse eyelashes (HP:0000653)1.96379260
116Increased serum lactate (HP:0002151)1.96247409
117Secondary amenorrhea (HP:0000869)1.95356362
118Hypoplasia of the fovea (HP:0007750)1.95128873
119Aplasia/Hypoplasia of the fovea (HP:0008060)1.95128873
120Aplasia/Hypoplasia of the sacrum (HP:0008517)1.94565237
121Impulsivity (HP:0100710)1.92125718
122Volvulus (HP:0002580)1.91641178
123Congenital, generalized hypertrichosis (HP:0004540)1.91285904
124Pancreatic cysts (HP:0001737)1.91155856
125Increased intramyocellular lipid droplets (HP:0012240)1.91059250
126Abnormality of B cell number (HP:0010975)1.90784841
127B lymphocytopenia (HP:0010976)1.90784841
128Supernumerary spleens (HP:0009799)1.89538126
129Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)1.89420846
130Exertional dyspnea (HP:0002875)1.88573599
131Exercise intolerance (HP:0003546)1.87081081
132Basal cell carcinoma (HP:0002671)1.87077040
133Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.84612945
134Abnormality of alanine metabolism (HP:0010916)1.84612945
135Hyperalaninemia (HP:0003348)1.84612945
136Patellar aplasia (HP:0006443)1.84329342
137Abnormal lung lobation (HP:0002101)1.84047750
138Duplicated collecting system (HP:0000081)1.83978379
139Sloping forehead (HP:0000340)1.83893105
140Chronic otitis media (HP:0000389)1.82646504
141Premature ovarian failure (HP:0008209)1.82385699
142Neoplasm of the pancreas (HP:0002894)1.81782219
143Recurrent viral infections (HP:0004429)1.81593195
144Irregular epiphyses (HP:0010582)1.81363243
145Recurrent bacterial skin infections (HP:0005406)1.81219230
146Stenosis of the external auditory canal (HP:0000402)1.80377237
147Aplasia/Hypoplasia of the patella (HP:0006498)1.80369854
148Recurrent fungal infections (HP:0002841)1.80263433
149Triphalangeal thumb (HP:0001199)1.80257305
150Hypoplasia of the uterus (HP:0000013)1.80254535
151Squamous cell carcinoma (HP:0002860)1.79650279
152Median cleft lip (HP:0000161)1.79608744
153Lethargy (HP:0001254)1.79526331
154Hyperglycinemia (HP:0002154)1.79367650
155Acute lymphatic leukemia (HP:0006721)1.79239913
156Rhabdomyosarcoma (HP:0002859)1.78760039
157Abnormality of the septum pellucidum (HP:0007375)1.77344097
158Abnormality of macular pigmentation (HP:0008002)1.74091522
159Abnormality of the fovea (HP:0000493)1.73972238
160Abnormality of aspartate family amino acid metabolism (HP:0010899)1.73542834
161Autoimmune thrombocytopenia (HP:0001973)1.71721480
162Abnormality of renal resorption (HP:0011038)1.71212725
163Absent septum pellucidum (HP:0001331)1.71015966
164Pancreatic fibrosis (HP:0100732)1.70651624
165Clubbing of toes (HP:0100760)1.67778616

Predicted kinase interactions (KEA)

RankGene SetZ-score
1WEE13.97348720
2EIF2AK13.55754211
3BUB13.36124071
4STK163.28918895
5NME23.23066988
6EIF2AK32.68832572
7CDC72.56484611
8VRK22.39639217
9SRPK12.28179555
10VRK12.16907557
11PRKCH2.12963350
12ACVR1B2.12595371
13DYRK32.04929863
14PIM21.95782341
15BRSK21.88718963
16MAP4K21.87385696
17PNCK1.85920204
18PLK41.84188583
19MAP4K11.82003807
20MKNK11.81040985
21TSSK61.78894444
22NEK21.77493965
23TLK11.74208549
24NME11.71467532
25MKNK21.69269084
26KIT1.68694083
27NEK11.67778198
28TEC1.63939795
29TXK1.61986197
30RPS6KA41.58940388
31CDK71.49590830
32TRIM281.48519432
33TAF11.45225857
34ATR1.44002432
35FLT31.43286490
36PLK11.40563586
37KDR1.38062290
38AURKB1.37492361
39TTK1.35058248
40TNIK1.31605854
41EIF2AK21.30851781
42BMPR1B1.27566727
43IRAK41.24122666
44NLK1.23790632
45CDK81.22592788
46DAPK11.21992023
47MAP2K61.20090899
48PIM11.19010303
49RPS6KB21.13736121
50PBK1.09576187
51STK101.08987089
52TAOK31.08044981
53PASK1.07625013
54PLK31.07397179
55CDK41.07369711
56MST41.06500256
57ZAK1.01322149
58SCYL20.99990496
59TGFBR10.99990279
60MAP3K80.99885231
61WNK30.97609310
62TESK20.96730184
63ERBB30.95912241
64JAK30.93167972
65IRAK30.90605451
66NUAK10.90031874
67IKBKB0.89771383
68MAP3K140.89426917
69CHEK20.85397238
70ALK0.84762291
71FRK0.82663510
72STK40.82343217
73ZAP700.80891908
74TYK20.79207084
75TBK10.79084025
76CHEK10.78872943
77BTK0.78700604
78AURKA0.77177093
79MAP2K30.76170220
80INSRR0.74167256
81BLK0.74022682
82NEK90.71631908
83CSNK2A20.70891022
84BRSK10.70104971
85MAP3K110.69584441
86CSNK2A10.68078789
87CDK30.64686749
88CLK10.64480855
89ATM0.63893584
90TAOK20.62314533
91LYN0.61190761
92PAK40.60744917
93TIE10.60614870
94RPS6KA50.57942736
95LCK0.56374445
96MATK0.55856339
97CSF1R0.55793864
98MAP3K50.54808893
99YES10.52608940
100SYK0.52486626
101CCNB10.51186110
102FES0.51169777
103CDK20.50949991
104CSNK1E0.50729119
105GRK10.50066999
106IKBKE0.49460896
107ADRBK10.48964828
108RAF10.48950777
109MAPKAPK30.47722643
110ERBB40.47682490
111STK240.47448905
112CHUK0.46874179
113LRRK20.46281879
114EPHA20.46190583
115OXSR10.44440590
116CSNK1G10.44304224
117PDK20.43859048
118STK390.43771489
119MUSK0.43749231
120PLK20.43631695
121IRAK10.41944221
122MAP3K30.40856635
123ABL20.40681259
124MAP3K120.40215093
125MARK30.36572246
126STK30.34950292
127MAPKAPK50.32946446
128CDK60.32466071
129CDK10.32453017
130DYRK20.30904092
131ADRBK20.30173848
132MAPK150.29805752
133ILK0.28699428
134CSNK1G30.27547164
135FGFR10.27351836
136GSK3A0.26948311
137CDK90.25738601
138PRKCQ0.24018890
139WNK40.23558682

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030304.49362799
2Ribosome_Homo sapiens_hsa030104.20226006
3Mismatch repair_Homo sapiens_hsa034303.77725563
4Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.48825573
5Proteasome_Homo sapiens_hsa030503.48698251
6* RNA polymerase_Homo sapiens_hsa030203.27420165
7Spliceosome_Homo sapiens_hsa030402.99930209
8Homologous recombination_Homo sapiens_hsa034402.98619937
9Base excision repair_Homo sapiens_hsa034102.67460310
10Nucleotide excision repair_Homo sapiens_hsa034202.67119775
11RNA transport_Homo sapiens_hsa030132.59230139
12* Pyrimidine metabolism_Homo sapiens_hsa002402.52254746
13Non-homologous end-joining_Homo sapiens_hsa034502.30170056
14Terpenoid backbone biosynthesis_Homo sapiens_hsa009002.22175674
15Cytosolic DNA-sensing pathway_Homo sapiens_hsa046232.14073981
16Cell cycle_Homo sapiens_hsa041102.13973269
17One carbon pool by folate_Homo sapiens_hsa006702.13008972
18Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006302.07852457
19Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.02181880
20Fanconi anemia pathway_Homo sapiens_hsa034601.96054112
21RNA degradation_Homo sapiens_hsa030181.88496405
22Basal transcription factors_Homo sapiens_hsa030221.77607330
23Protein export_Homo sapiens_hsa030601.63008703
24p53 signaling pathway_Homo sapiens_hsa041151.48972966
25Alzheimers disease_Homo sapiens_hsa050101.48080469
26Antigen processing and presentation_Homo sapiens_hsa046121.39180432
27Primary immunodeficiency_Homo sapiens_hsa053401.35564125
28* Purine metabolism_Homo sapiens_hsa002301.31881915
29Herpes simplex infection_Homo sapiens_hsa051681.28613897
30Epstein-Barr virus infection_Homo sapiens_hsa051691.20892378
31Folate biosynthesis_Homo sapiens_hsa007901.13674806
32Systemic lupus erythematosus_Homo sapiens_hsa053221.12238173
33mRNA surveillance pathway_Homo sapiens_hsa030151.04765872
34Fatty acid elongation_Homo sapiens_hsa000621.01424259
35Measles_Homo sapiens_hsa051621.01121189
36Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.98356572
37NF-kappa B signaling pathway_Homo sapiens_hsa040640.97248731
38Sulfur relay system_Homo sapiens_hsa041220.91464484
39RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.90929686
40Legionellosis_Homo sapiens_hsa051340.88756647
41Hematopoietic cell lineage_Homo sapiens_hsa046400.88699349
42Selenocompound metabolism_Homo sapiens_hsa004500.87714070
43Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.87493539
44Viral carcinogenesis_Homo sapiens_hsa052030.84121100
45Allograft rejection_Homo sapiens_hsa053300.83196230
46Propanoate metabolism_Homo sapiens_hsa006400.82149220
47NOD-like receptor signaling pathway_Homo sapiens_hsa046210.79817258
48Pentose phosphate pathway_Homo sapiens_hsa000300.79265661
49Thyroid cancer_Homo sapiens_hsa052160.77724113
50Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.70823996
51Cysteine and methionine metabolism_Homo sapiens_hsa002700.70648101
52Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.69872249
53Leishmaniasis_Homo sapiens_hsa051400.69079548
54Drug metabolism - other enzymes_Homo sapiens_hsa009830.68612748
55Graft-versus-host disease_Homo sapiens_hsa053320.68357089
56Intestinal immune network for IgA production_Homo sapiens_hsa046720.67284118
57Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.61889467
58Apoptosis_Homo sapiens_hsa042100.61613070
59Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.60766903
60Transcriptional misregulation in cancer_Homo sapiens_hsa052020.58546698
61HTLV-I infection_Homo sapiens_hsa051660.57862691
62Shigellosis_Homo sapiens_hsa051310.57460782
63Sulfur metabolism_Homo sapiens_hsa009200.56628327
64Rheumatoid arthritis_Homo sapiens_hsa053230.55794214
65Cardiac muscle contraction_Homo sapiens_hsa042600.55163608
66Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.55098311
67Pyruvate metabolism_Homo sapiens_hsa006200.54785930
68SNARE interactions in vesicular transport_Homo sapiens_hsa041300.53897006
69Asthma_Homo sapiens_hsa053100.53829910
70Influenza A_Homo sapiens_hsa051640.53717306
71Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.52917618
72Hepatitis B_Homo sapiens_hsa051610.52914352
73Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.52621159
74Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.52353574
75Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.52208863
76Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.51867592
77Phototransduction_Homo sapiens_hsa047440.50837982
78Jak-STAT signaling pathway_Homo sapiens_hsa046300.50365830
79Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.50123200
80Huntingtons disease_Homo sapiens_hsa050160.49759408
81Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.46594920
82Acute myeloid leukemia_Homo sapiens_hsa052210.46274275
83Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.44605476
84Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.43784803
85Maturity onset diabetes of the young_Homo sapiens_hsa049500.43227673
86Parkinsons disease_Homo sapiens_hsa050120.42854518
87Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.42031162
88Small cell lung cancer_Homo sapiens_hsa052220.41618703
89Other glycan degradation_Homo sapiens_hsa005110.40660625
90Linoleic acid metabolism_Homo sapiens_hsa005910.40326065
91Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.39799292
92Carbon metabolism_Homo sapiens_hsa012000.39725181
93Peroxisome_Homo sapiens_hsa041460.39052582
94Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.38682672
95Type I diabetes mellitus_Homo sapiens_hsa049400.37211001
96Toll-like receptor signaling pathway_Homo sapiens_hsa046200.36845834
972-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.36834894
98Chemical carcinogenesis_Homo sapiens_hsa052040.36662700
99Butanoate metabolism_Homo sapiens_hsa006500.36353945
100B cell receptor signaling pathway_Homo sapiens_hsa046620.35666230
101N-Glycan biosynthesis_Homo sapiens_hsa005100.35343952
102Caffeine metabolism_Homo sapiens_hsa002320.30702300
103Pentose and glucuronate interconversions_Homo sapiens_hsa000400.29935575
104Cyanoamino acid metabolism_Homo sapiens_hsa004600.29905730
105Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.29013559
106Oocyte meiosis_Homo sapiens_hsa041140.27157991
107Glutathione metabolism_Homo sapiens_hsa004800.26988687
108T cell receptor signaling pathway_Homo sapiens_hsa046600.26872458
109Biosynthesis of amino acids_Homo sapiens_hsa012300.26529795
110Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.26383740
111Glycerolipid metabolism_Homo sapiens_hsa005610.24704339
112Oxidative phosphorylation_Homo sapiens_hsa001900.24657400
113Malaria_Homo sapiens_hsa051440.24154056
114Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.23704176
115Autoimmune thyroid disease_Homo sapiens_hsa053200.23659069
116Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.23340819
117Alcoholism_Homo sapiens_hsa050340.22722548
118Pertussis_Homo sapiens_hsa051330.22427702
119Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.22217625
120Osteoclast differentiation_Homo sapiens_hsa043800.22083775
121TNF signaling pathway_Homo sapiens_hsa046680.21839810
122MicroRNAs in cancer_Homo sapiens_hsa052060.21555129
123* Metabolic pathways_Homo sapiens_hsa011000.21537648
124Colorectal cancer_Homo sapiens_hsa052100.20533164
125Olfactory transduction_Homo sapiens_hsa047400.20446024
126TGF-beta signaling pathway_Homo sapiens_hsa043500.20214497
127Regulation of autophagy_Homo sapiens_hsa041400.19040663
128Toxoplasmosis_Homo sapiens_hsa051450.18742515
129Nitrogen metabolism_Homo sapiens_hsa009100.18164868
130Viral myocarditis_Homo sapiens_hsa054160.17924719
131Vitamin B6 metabolism_Homo sapiens_hsa007500.17644487
132Ether lipid metabolism_Homo sapiens_hsa005650.17352156
133Tuberculosis_Homo sapiens_hsa051520.16827952
134Arachidonic acid metabolism_Homo sapiens_hsa005900.15789576
135Steroid biosynthesis_Homo sapiens_hsa001000.15322274
136Tryptophan metabolism_Homo sapiens_hsa003800.15225345
137alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.14118283
138Renin-angiotensin system_Homo sapiens_hsa046140.12861400
139Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.12842410

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