TXNDC16

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1axon ensheathment in central nervous system (GO:0032291)6.98948407
2central nervous system myelination (GO:0022010)6.98948407
3pyrimidine nucleobase catabolic process (GO:0006208)5.59105121
4nucleobase catabolic process (GO:0046113)4.49135087
5myelination (GO:0042552)4.46270869
6ensheathment of neurons (GO:0007272)4.42854404
7axon ensheathment (GO:0008366)4.42854404
8long-chain fatty acid biosynthetic process (GO:0042759)4.39824174
9presynaptic membrane assembly (GO:0097105)4.38709483
10presynaptic membrane organization (GO:0097090)4.33213725
11neuron cell-cell adhesion (GO:0007158)4.30971893
12negative regulation of neurotransmitter secretion (GO:0046929)4.16148632
13L-amino acid import (GO:0043092)4.13478530
14negative regulation of neurotransmitter transport (GO:0051589)4.09681024
15fatty acid elongation (GO:0030497)3.69411467
16transmission of nerve impulse (GO:0019226)3.64280634
17oligodendrocyte differentiation (GO:0048709)3.49308633
18neuronal action potential propagation (GO:0019227)3.48700797
19cerebral cortex radially oriented cell migration (GO:0021799)3.48242798
20negative regulation of protein localization to cell surface (GO:2000009)3.42926258
21glycerophospholipid catabolic process (GO:0046475)3.41464414
22negative regulation of synaptic transmission, GABAergic (GO:0032229)3.41416347
23DNA double-strand break processing (GO:0000729)3.31518752
24adult walking behavior (GO:0007628)3.28823805
25retinal ganglion cell axon guidance (GO:0031290)3.27266161
26regulation of synaptic vesicle exocytosis (GO:2000300)3.26847375
27regulation of short-term neuronal synaptic plasticity (GO:0048172)3.26170907
28positive regulation of excitatory postsynaptic membrane potential (GO:2000463)3.25889233
29ionotropic glutamate receptor signaling pathway (GO:0035235)3.23015199
30mitotic sister chromatid cohesion (GO:0007064)3.22810714
31amino acid import (GO:0043090)3.09985022
32regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act3.09656118
33gamma-aminobutyric acid signaling pathway (GO:0007214)3.07754505
34nonmotile primary cilium assembly (GO:0035058)3.07678028
35synaptic vesicle exocytosis (GO:0016079)3.05866615
36cerebellar granule cell differentiation (GO:0021707)3.05447897
37photoreceptor cell differentiation (GO:0046530)3.05030099
38eye photoreceptor cell differentiation (GO:0001754)3.05030099
39auditory behavior (GO:0031223)3.02168676
40positive regulation of action potential (GO:0045760)3.01132700
41locomotory exploration behavior (GO:0035641)3.00881808
42neuron recognition (GO:0008038)2.99698887
43synaptic transmission, glutamatergic (GO:0035249)2.99223425
44neuron-neuron synaptic transmission (GO:0007270)2.95885586
45hippocampus development (GO:0021766)2.95666280
46myelin maintenance (GO:0043217)2.92464367
47glutamate receptor signaling pathway (GO:0007215)2.92359159
48mitochondrion transport along microtubule (GO:0047497)2.89725125
49establishment of mitochondrion localization, microtubule-mediated (GO:0034643)2.89725125
50neural tube formation (GO:0001841)2.89600867
51negative regulation of synaptic transmission, glutamatergic (GO:0051967)2.89233173
52protein localization to synapse (GO:0035418)2.89182394
53regulation of collateral sprouting (GO:0048670)2.89163723
54establishment of nucleus localization (GO:0040023)2.87377532
55central nervous system projection neuron axonogenesis (GO:0021952)2.87064112
56startle response (GO:0001964)2.86094580
57synaptic vesicle maturation (GO:0016188)2.85352319
58neuronal ion channel clustering (GO:0045161)2.84801104
59astrocyte development (GO:0014002)2.82136070
60neurotransmitter-gated ion channel clustering (GO:0072578)2.81769955
61cyclic nucleotide catabolic process (GO:0009214)2.81372556
62neuron remodeling (GO:0016322)2.81195213
63regulation of voltage-gated calcium channel activity (GO:1901385)2.79858633
64vocalization behavior (GO:0071625)2.79005227
65apical protein localization (GO:0045176)2.78894594
66peptidyl-tyrosine autophosphorylation (GO:0038083)2.78253996
67regulation of synaptic vesicle transport (GO:1902803)2.77124452
68positive regulation of dendritic spine morphogenesis (GO:0061003)2.76418308
69import into cell (GO:0098657)2.76067940
70membrane depolarization during cardiac muscle cell action potential (GO:0086012)2.75712062
71nuclear pore complex assembly (GO:0051292)2.75426224
72positive regulation of mitochondrial fission (GO:0090141)2.74746375
73organelle transport along microtubule (GO:0072384)2.74186328
74nuclear pore organization (GO:0006999)2.73393211
75intraciliary transport (GO:0042073)2.72912581
76nerve growth factor signaling pathway (GO:0038180)2.72545597
77asymmetric protein localization (GO:0008105)2.69097398
78long-term synaptic potentiation (GO:0060291)2.68540549
79negative regulation of axonogenesis (GO:0050771)2.67131437
80axonal fasciculation (GO:0007413)2.66986767
81Golgi to endosome transport (GO:0006895)2.66864522
82olfactory bulb development (GO:0021772)2.66170932
83microtubule anchoring (GO:0034453)2.64298378
84regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)2.63545129
85neurofilament cytoskeleton organization (GO:0060052)2.62019174
86regulation of glutamate receptor signaling pathway (GO:1900449)2.61916981
87negative regulation of peptidyl-threonine phosphorylation (GO:0010801)2.61482141
88postsynaptic membrane organization (GO:0001941)2.61116755
89glutamate secretion (GO:0014047)2.60651219
90myelination in peripheral nervous system (GO:0022011)2.57921090
91peripheral nervous system axon ensheathment (GO:0032292)2.57921090
92regulation of cAMP-dependent protein kinase activity (GO:2000479)2.57296088
93regulation of respiratory gaseous exchange by neurological system process (GO:0002087)2.56404744
94central nervous system neuron axonogenesis (GO:0021955)2.56337421
95cerebral cortex cell migration (GO:0021795)2.55905170
96regulation of synaptic transmission, glutamatergic (GO:0051966)2.55863936
97regulation of inhibitory postsynaptic membrane potential (GO:0060080)2.55761927
98establishment of protein localization to Golgi (GO:0072600)2.55280868
99vesicle transport along microtubule (GO:0047496)2.55084913
100gamma-aminobutyric acid transport (GO:0015812)2.54359696
101positive regulation of oligodendrocyte differentiation (GO:0048714)2.54186449
102protein targeting to Golgi (GO:0000042)2.53588525
103dendrite morphogenesis (GO:0048813)2.53484387
104regulation of dendritic spine morphogenesis (GO:0061001)2.52483215
105regulation of excitatory postsynaptic membrane potential (GO:0060079)2.52453553
106negative regulation of synaptic transmission (GO:0050805)2.51684760
107cytoskeleton-dependent intracellular transport (GO:0030705)2.51270591
108mechanosensory behavior (GO:0007638)2.50911543
109neurotransmitter uptake (GO:0001504)2.50597724
110microtubule-based transport (GO:0010970)2.50164105
111adult locomotory behavior (GO:0008344)2.49982835
112cerebellar Purkinje cell differentiation (GO:0021702)2.49697990
113substrate-independent telencephalic tangential interneuron migration (GO:0021843)2.49054925
114substrate-independent telencephalic tangential migration (GO:0021826)2.49054925
115limb bud formation (GO:0060174)2.48392412
116synapse assembly (GO:0007416)2.48302568
117membrane assembly (GO:0071709)2.47650747
118synaptic vesicle endocytosis (GO:0048488)2.47494866
119regulation of synaptic transmission, GABAergic (GO:0032228)2.45256512
120response to redox state (GO:0051775)2.44955238
121dendritic spine morphogenesis (GO:0060997)2.44506587
122G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.44093106
123positive regulation of calcium ion-dependent exocytosis (GO:0045956)2.44059613
124establishment of mitochondrion localization (GO:0051654)2.43673110
125negative regulation of axon extension (GO:0030517)2.43239785
126dendrite development (GO:0016358)2.43216204
127positive regulation of potassium ion transmembrane transporter activity (GO:1901018)2.42557971
128regulation of neuronal synaptic plasticity (GO:0048168)2.42480249
129regulation of DNA endoreduplication (GO:0032875)2.42180767
130mitochondrial outer membrane permeabilization involved in programmed cell death (GO:1902686)2.42048511
131positive regulation of mitochondrial membrane permeability involved in apoptotic process (GO:19021102.42048511
132cellular response to monoamine stimulus (GO:0071868)2.41494866
133cellular response to catecholamine stimulus (GO:0071870)2.41494866
134positive regulation of cell cycle checkpoint (GO:1901978)2.41382556
135negative regulation of DNA recombination (GO:0045910)2.41038973
136regulation of neurotransmitter secretion (GO:0046928)2.39519166
137positive regulation of membrane potential (GO:0045838)2.39277765
138magnesium ion transport (GO:0015693)2.39232719
139negative regulation of oligodendrocyte differentiation (GO:0048715)2.38937995
140retrograde transport, vesicle recycling within Golgi (GO:0000301)2.37133860
141regulation of postsynaptic membrane potential (GO:0060078)2.36927471
142membrane hyperpolarization (GO:0060081)2.36843753
143regulation of cilium movement (GO:0003352)2.36098909
144calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339)2.35550489
145neuron migration (GO:0001764)2.32850906
146axonogenesis (GO:0007409)2.32640723
147vesicle localization (GO:0051648)2.32640369
148striatum development (GO:0021756)2.32440824
149chromatin remodeling at centromere (GO:0031055)2.30459564
150regulation of centriole replication (GO:0046599)2.30176673
151righting reflex (GO:0060013)2.29512278
152CENP-A containing nucleosome assembly (GO:0034080)2.29443511
153prostate gland growth (GO:0060736)2.29265743
154pore complex assembly (GO:0046931)2.28183936
155establishment of vesicle localization (GO:0051650)2.27380874
156synapse organization (GO:0050808)2.27379190
157glycosphingolipid biosynthetic process (GO:0006688)2.27311330
158regulation of telomere maintenance (GO:0032204)2.27287229
159forebrain neuron differentiation (GO:0021879)2.26320276

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1GBX2_23144817_ChIP-Seq_PC3_Human4.08661067
2EZH2_22144423_ChIP-Seq_EOC_Human3.62984767
3NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.86106804
4RBPJ_22232070_ChIP-Seq_NCS_Mouse2.85554350
5SALL1_21062744_ChIP-ChIP_HESCs_Human2.80067158
6SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.52133331
7SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.42336940
8JARID2_20064375_ChIP-Seq_MESCs_Mouse2.40483257
9TAF15_26573619_Chip-Seq_HEK293_Human2.34592224
10HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.26146405
11ZFP57_27257070_Chip-Seq_ESCs_Mouse2.25320746
12ZNF274_21170338_ChIP-Seq_K562_Hela2.21060988
13RNF2_18974828_ChIP-Seq_MESCs_Mouse2.12252622
14EZH2_18974828_ChIP-Seq_MESCs_Mouse2.12252622
15EZH2_27304074_Chip-Seq_ESCs_Mouse2.09605441
16SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.09309171
17SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.08513318
18SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.01031398
19MTF2_20144788_ChIP-Seq_MESCs_Mouse1.98631939
20EED_16625203_ChIP-ChIP_MESCs_Mouse1.98094368
21AR_21572438_ChIP-Seq_LNCaP_Human1.97641368
22GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.96116075
23GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.95504156
24* SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.92475833
25DROSHA_22980978_ChIP-Seq_HELA_Human1.91713843
26SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.89717793
27POU3F2_20337985_ChIP-ChIP_501MEL_Human1.87612394
28JARID2_20075857_ChIP-Seq_MESCs_Mouse1.86261342
29PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.85722993
30BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.85087278
31CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.82297552
32EZH2_27294783_Chip-Seq_ESCs_Mouse1.79059326
33SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.78376499
34RNF2_27304074_Chip-Seq_ESCs_Mouse1.78012334
35OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.75850916
36SUZ12_27294783_Chip-Seq_ESCs_Mouse1.74633893
37VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.71151234
38TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.70119969
39P300_19829295_ChIP-Seq_ESCs_Human1.69331102
40CTBP2_25329375_ChIP-Seq_LNCAP_Human1.67254151
41KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.67050514
42CTBP1_25329375_ChIP-Seq_LNCAP_Human1.65687056
43SMAD4_21799915_ChIP-Seq_A2780_Human1.63470278
44CDX2_19796622_ChIP-Seq_MESCs_Mouse1.62510490
45CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.61326819
46CBX2_27304074_Chip-Seq_ESCs_Mouse1.60300210
47REST_21632747_ChIP-Seq_MESCs_Mouse1.60078770
48ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.59804360
49MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.59532748
50ER_23166858_ChIP-Seq_MCF-7_Human1.55762838
51SMAD_19615063_ChIP-ChIP_OVARY_Human1.55022148
52PIAS1_25552417_ChIP-Seq_VCAP_Human1.54905304
53SMAD3_21741376_ChIP-Seq_EPCs_Human1.54365928
54RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.54287721
55BMI1_23680149_ChIP-Seq_NPCS_Mouse1.50680867
56FUS_26573619_Chip-Seq_HEK293_Human1.48945074
57POU5F1_16153702_ChIP-ChIP_HESCs_Human1.45244584
58IGF1R_20145208_ChIP-Seq_DFB_Human1.42448464
59NANOG_18555785_Chip-Seq_ESCs_Mouse1.41007610
60SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.40779825
61CBP_20019798_ChIP-Seq_JUKART_Human1.40470344
62IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.40470344
63TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.39848683
64* STAT3_23295773_ChIP-Seq_U87_Human1.39817276
65RARB_27405468_Chip-Seq_BRAIN_Mouse1.35456036
66* AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.35190583
67RNF2_27304074_Chip-Seq_NSC_Mouse1.35126950
68PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.34345739
69TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.33978557
70TCF4_23295773_ChIP-Seq_U87_Human1.30622240
71E2F4_17652178_ChIP-ChIP_JURKAT_Human1.30406652
72IKZF1_21737484_ChIP-ChIP_HCT116_Human1.29311248
73CMYC_18555785_Chip-Seq_ESCs_Mouse1.27264554
74EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.26139714
75PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.25571290
76E2F7_22180533_ChIP-Seq_HELA_Human1.25353933
77VDR_22108803_ChIP-Seq_LS180_Human1.25146769
78FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.23066764
79PCGF2_27294783_Chip-Seq_ESCs_Mouse1.22944864
80MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.22632946
81E2F1_18555785_Chip-Seq_ESCs_Mouse1.22532368
82MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.22178478
83SOX9_26525672_Chip-Seq_HEART_Mouse1.22075612
84ARNT_22903824_ChIP-Seq_MCF-7_Human1.21989908
85SUZ12_18555785_Chip-Seq_ESCs_Mouse1.21706530
86TOP2B_26459242_ChIP-Seq_MCF-7_Human1.20833514
87HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.20685786
88* KLF5_20875108_ChIP-Seq_MESCs_Mouse1.20516097
89TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.20484521
90FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.19958686
91IRF1_19129219_ChIP-ChIP_H3396_Human1.19617018
92P53_22387025_ChIP-Seq_ESCs_Mouse1.19272613
93ZNF217_24962896_ChIP-Seq_MCF-7_Human1.18705860
94FLI1_27457419_Chip-Seq_LIVER_Mouse1.17894682
95P53_22127205_ChIP-Seq_FIBROBLAST_Human1.17873618
96TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.17029329
97REST_18959480_ChIP-ChIP_MESCs_Mouse1.16878808
98AR_25329375_ChIP-Seq_VCAP_Human1.16354687
99SOX2_21211035_ChIP-Seq_LN229_Gbm1.16113311
100RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.15303798
101P300_18555785_Chip-Seq_ESCs_Mouse1.14805315
102PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.14412581
103UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.14241782
104SOX2_16153702_ChIP-ChIP_HESCs_Human1.13539898
105WT1_19549856_ChIP-ChIP_CCG9911_Human1.12593682
106AHR_22903824_ChIP-Seq_MCF-7_Human1.12520383
107E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.11997498
108RUNX2_22187159_ChIP-Seq_PCA_Human1.11229238
109SUZ12_27294783_Chip-Seq_NPCs_Mouse1.10515212
110STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.10123218
111EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.09958374
112PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.09335287
113TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.08032422
114POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.08032422
115MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.07895455
116STAT3_18555785_Chip-Seq_ESCs_Mouse1.07892835
117NR3C1_21868756_ChIP-Seq_MCF10A_Human1.07655737
118PRDM14_20953172_ChIP-Seq_ESCs_Human1.07627656
119EWS_26573619_Chip-Seq_HEK293_Human1.05758561
120KDM2B_26808549_Chip-Seq_REH_Human1.05652375
121* FLI1_21867929_ChIP-Seq_TH2_Mouse1.05360713
122SOX2_18555785_Chip-Seq_ESCs_Mouse1.04510114
123CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.04399115
124FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.04114349
125TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.03769351
126YAP1_20516196_ChIP-Seq_MESCs_Mouse1.03689301
127TAL1_26923725_Chip-Seq_HPCs_Mouse1.03001653
128RUNX1_27457419_Chip-Seq_LIVER_Mouse1.02648575
129EZH2_27294783_Chip-Seq_NPCs_Mouse1.02297102
130HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.01617124
131PADI4_21655091_ChIP-ChIP_MCF-7_Human1.01391677
132JUN_21703547_ChIP-Seq_K562_Human1.01080252
133LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse0.99973625
134LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.99913001
135STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse0.99751372
136TBX3_20139965_ChIP-Seq_MESCs_Mouse0.98809647
137NMYC_18555785_Chip-Seq_ESCs_Mouse0.98633637

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003880_abnormal_central_pattern4.25962804
2MP0004859_abnormal_synaptic_plasticity3.81160970
3MP0000920_abnormal_myelination3.42406192
4MP0004270_analgesia3.07817769
5MP0001486_abnormal_startle_reflex2.91408154
6MP0002064_seizures2.76174188
7MP0003635_abnormal_synaptic_transmissio2.74621591
8MP0005171_absent_coat_pigmentation2.72549193
9MP0002272_abnormal_nervous_system2.65987545
10MP0009745_abnormal_behavioral_response2.63354350
11MP0003121_genomic_imprinting2.55758985
12MP0003690_abnormal_glial_cell2.51651205
13MP0005423_abnormal_somatic_nervous2.44706698
14MP0004742_abnormal_vestibular_system2.44136718
15MP0009046_muscle_twitch2.42130420
16MP0004885_abnormal_endolymph2.36859251
17MP0003122_maternal_imprinting2.28261721
18MP0008057_abnormal_DNA_replication2.27457251
19MP0002572_abnormal_emotion/affect_behav2.22236731
20MP0002063_abnormal_learning/memory/cond2.20579010
21MP0000778_abnormal_nervous_system2.18663867
22MP0001529_abnormal_vocalization2.07157544
23MP0002734_abnormal_mechanical_nocicepti2.04871707
24MP0001968_abnormal_touch/_nociception2.01446539
25MP0005409_darkened_coat_color2.00382878
26MP0003890_abnormal_embryonic-extraembry1.98266850
27MP0002009_preneoplasia1.96649305
28MP0005646_abnormal_pituitary_gland1.92338558
29MP0001905_abnormal_dopamine_level1.90651818
30MP0002736_abnormal_nociception_after1.84810814
31MP0005551_abnormal_eye_electrophysiolog1.84108515
32MP0002067_abnormal_sensory_capabilities1.83103143
33MP0003136_yellow_coat_color1.80158361
34MP0001188_hyperpigmentation1.79403211
35MP0008569_lethality_at_weaning1.76674700
36MP0000569_abnormal_digit_pigmentation1.73198243
37MP0003634_abnormal_glial_cell1.72001709
38MP0003221_abnormal_cardiomyocyte_apopto1.68881245
39MP0001440_abnormal_grooming_behavior1.66892508
40MP0005394_taste/olfaction_phenotype1.65548026
41MP0005499_abnormal_olfactory_system1.65548026
42MP0004142_abnormal_muscle_tone1.65528775
43MP0002735_abnormal_chemical_nociception1.63359688
44MP0005187_abnormal_penis_morphology1.61420497
45MP0001485_abnormal_pinna_reflex1.61041608
46MP0003787_abnormal_imprinting1.60922479
47MP0003950_abnormal_plasma_membrane1.60802800
48MP0004924_abnormal_behavior1.57101666
49MP0005386_behavior/neurological_phenoty1.57101666
50MP0002822_catalepsy1.53434485
51MP0002229_neurodegeneration1.52823347
52MP0000955_abnormal_spinal_cord1.49404495
53MP0002882_abnormal_neuron_morphology1.48498670
54MP0001501_abnormal_sleep_pattern1.48168219
55MP0002234_abnormal_pharynx_morphology1.47203169
56MP0001963_abnormal_hearing_physiology1.46980858
57MP0001970_abnormal_pain_threshold1.45350380
58MP0003632_abnormal_nervous_system1.43995443
59MP0005645_abnormal_hypothalamus_physiol1.43211399
60MP0003123_paternal_imprinting1.40939017
61MP0003329_amyloid_beta_deposits1.38786735
62MP0002751_abnormal_autonomic_nervous1.37027264
63MP0008789_abnormal_olfactory_epithelium1.36737369
64MP0002557_abnormal_social/conspecific_i1.33191300
65MP0005248_abnormal_Harderian_gland1.31985943
66MP0003631_nervous_system_phenotype1.31001837
67MP0008058_abnormal_DNA_repair1.28234231
68MP0009697_abnormal_copulation1.28143214
69MP0002066_abnormal_motor_capabilities/c1.28075048
70MP0001984_abnormal_olfaction1.24305061
71MP0003633_abnormal_nervous_system1.22415798
72MP0002184_abnormal_innervation1.21462663
73MP0002733_abnormal_thermal_nociception1.20590068
74MP0008260_abnormal_autophagy1.17131733
75MP0003861_abnormal_nervous_system1.16598131
76MP0002752_abnormal_somatic_nervous1.16497668
77MP0001177_atelectasis1.15391622
78MP0001502_abnormal_circadian_rhythm1.14850780
79MP0002638_abnormal_pupillary_reflex1.14540042
80MP0000383_abnormal_hair_follicle1.14267226
81MP0009780_abnormal_chondrocyte_physiolo1.13927507
82MP0000631_abnormal_neuroendocrine_gland1.10256302
83MP0000026_abnormal_inner_ear1.09916392
84MP0002909_abnormal_adrenal_gland1.08538754
85MP0004134_abnormal_chest_morphology1.08144303
86MP0000015_abnormal_ear_pigmentation1.06781023
87MP0009703_decreased_birth_body1.04543718
88MP0005410_abnormal_fertilization1.03994626
89MP0003119_abnormal_digestive_system1.03916345
90MP0008995_early_reproductive_senescence1.03719682
91MP0010678_abnormal_skin_adnexa1.01813811
92MP0003698_abnormal_male_reproductive1.01557901
93MP0006276_abnormal_autonomic_nervous1.00180072
94MP0003567_abnormal_fetal_cardiomyocyte0.98403934
95MP0004811_abnormal_neuron_physiology0.98257334
96MP0002233_abnormal_nose_morphology0.97812105
97MP0004043_abnormal_pH_regulation0.96279274
98MP0000462_abnormal_digestive_system0.95410501
99MP0003183_abnormal_peptide_metabolism0.95341060
100MP0005391_vision/eye_phenotype0.94153690
101MP0005253_abnormal_eye_physiology0.94019270
102MP0002152_abnormal_brain_morphology0.93078797
103MP0002210_abnormal_sex_determination0.89742028
104MP0005195_abnormal_posterior_eye0.89051816
105MP0003937_abnormal_limbs/digits/tail_de0.89019646
106MP0006072_abnormal_retinal_apoptosis0.88938717
107MP0001986_abnormal_taste_sensitivity0.88053346
108MP0002876_abnormal_thyroid_physiology0.86861268
109MP0002653_abnormal_ependyma_morphology0.86768252
110MP0000647_abnormal_sebaceous_gland0.86723210
111MP0003879_abnormal_hair_cell0.85578574
112MP0003938_abnormal_ear_development0.85131657
113MP0001929_abnormal_gametogenesis0.84485792
114MP0004381_abnormal_hair_follicle0.83564644
115MP0002090_abnormal_vision0.81313301
116MP0010094_abnormal_chromosome_stability0.79981661
117MP0004133_heterotaxia0.79974673
118MP0003755_abnormal_palate_morphology0.79568598
119MP0001299_abnormal_eye_distance/0.79427275
120MP0005310_abnormal_salivary_gland0.78685615
121MP0003656_abnormal_erythrocyte_physiolo0.77168058
122MP0003315_abnormal_perineum_morphology0.76908205
123MP0002837_dystrophic_cardiac_calcinosis0.76815510
124MP0002697_abnormal_eye_size0.76311845
125MP0001293_anophthalmia0.76007857
126MP0001145_abnormal_male_reproductive0.75680331
127MP0000653_abnormal_sex_gland0.75277572
128MP0002160_abnormal_reproductive_system0.75039725
129MP0001324_abnormal_eye_pigmentation0.72256868
130MP0002081_perinatal_lethality0.71953141
131MP0001346_abnormal_lacrimal_gland0.71719646
132MP0002102_abnormal_ear_morphology0.70228741
133MP0008877_abnormal_DNA_methylation0.68845527
134MP0006292_abnormal_olfactory_placode0.66960459
135MP0000566_synostosis0.65536398
136MP0004147_increased_porphyrin_level0.62475302
137MP0003172_abnormal_lysosome_physiology0.62321614
138MP0000681_abnormal_thyroid_gland0.61423819
139MP0001943_abnormal_respiration0.57345032
140MP0000372_irregular_coat_pigmentation0.54901356
141MP0004145_abnormal_muscle_electrophysio0.54448821
142MP0000604_amyloidosis0.53222564
143MP0002069_abnormal_eating/drinking_beha0.52438029
144MP0002133_abnormal_respiratory_system0.52144003
145MP0005388_respiratory_system_phenotype0.52144003

Predicted human phenotypes

RankGene SetZ-score
1Degeneration of the lateral corticospinal tracts (HP:0002314)5.07100499
2Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)5.07100499
3Focal motor seizures (HP:0011153)4.43016274
4Neurofibrillary tangles (HP:0002185)4.12066929
5Volvulus (HP:0002580)4.11724505
6Abnormality of the corticospinal tract (HP:0002492)3.99959292
7Myokymia (HP:0002411)3.44393344
8Peripheral hypomyelination (HP:0007182)3.43957766
9Epileptic encephalopathy (HP:0200134)3.36944826
10Parakeratosis (HP:0001036)3.34886384
11Cortical dysplasia (HP:0002539)3.31608870
12Hepatoblastoma (HP:0002884)3.17594525
13Sensory axonal neuropathy (HP:0003390)3.16470510
14Papillary thyroid carcinoma (HP:0002895)3.14176960
15Atonic seizures (HP:0010819)3.05067925
16Spastic gait (HP:0002064)3.04493075
17Supranuclear gaze palsy (HP:0000605)3.02606847
18Ankle clonus (HP:0011448)3.00271060
19Febrile seizures (HP:0002373)2.99991721
20Onion bulb formation (HP:0003383)2.91234068
21Dysmetria (HP:0001310)2.89536762
22Focal seizures (HP:0007359)2.85378185
23Insidious onset (HP:0003587)2.80219235
24Termporal pattern (HP:0011008)2.80219235
25Abnormality of the labia minora (HP:0012880)2.79844869
26Broad-based gait (HP:0002136)2.74055698
27Action tremor (HP:0002345)2.71020524
28Scanning speech (HP:0002168)2.65750422
29Poor coordination (HP:0002370)2.65266851
30Hyperventilation (HP:0002883)2.64855714
31Cerebral inclusion bodies (HP:0100314)2.64446451
32Gaze-evoked nystagmus (HP:0000640)2.58760635
33Intention tremor (HP:0002080)2.58674558
34Progressive cerebellar ataxia (HP:0002073)2.57546908
35Abnormal auditory evoked potentials (HP:0006958)2.56882591
36Akinesia (HP:0002304)2.56188605
37Thickened helices (HP:0000391)2.53117682
38Alacrima (HP:0000522)2.50682184
39Impaired vibration sensation in the lower limbs (HP:0002166)2.46398407
40Amyotrophic lateral sclerosis (HP:0007354)2.43375776
41Protruding tongue (HP:0010808)2.42647955
42Intestinal atresia (HP:0011100)2.42454092
43Gonadotropin excess (HP:0000837)2.38237486
44Thyroid carcinoma (HP:0002890)2.37363527
45Absent septum pellucidum (HP:0001331)2.35854437
46White forelock (HP:0002211)2.35214474
47Genetic anticipation (HP:0003743)2.34625604
48Absent speech (HP:0001344)2.33525762
49Inappropriate behavior (HP:0000719)2.31569394
50Clumsiness (HP:0002312)2.31125784
51Unilateral renal agenesis (HP:0000122)2.29825674
52Medulloblastoma (HP:0002885)2.28913554
53Widely spaced teeth (HP:0000687)2.28607406
54Broad foot (HP:0001769)2.27407293
55Polyphagia (HP:0002591)2.25970171
56Blue irides (HP:0000635)2.25327013
57Septo-optic dysplasia (HP:0100842)2.23167291
58Patchy hypopigmentation of hair (HP:0011365)2.22980067
59Truncal obesity (HP:0001956)2.21604524
60Gait imbalance (HP:0002141)2.21115550
61Medial flaring of the eyebrow (HP:0010747)2.20991963
62Decreased lacrimation (HP:0000633)2.20752239
63Optic nerve hypoplasia (HP:0000609)2.20357195
64Lower limb muscle weakness (HP:0007340)2.20213884
65Progressive inability to walk (HP:0002505)2.17060497
66Congenital sensorineural hearing impairment (HP:0008527)2.16860112
67Vaginal atresia (HP:0000148)2.15378436
68Genital tract atresia (HP:0001827)2.14284430
69Retinal dysplasia (HP:0007973)2.13793407
70Exotropia (HP:0000577)2.10371886
71Slow saccadic eye movements (HP:0000514)2.07906019
72Hypsarrhythmia (HP:0002521)2.06614065
73Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)2.05966162
74Abnormal hair whorl (HP:0010721)2.05735443
75Menstrual irregularities (HP:0000858)2.03447913
76Aplasia involving bones of the extremities (HP:0009825)2.03048625
77Aplasia involving bones of the upper limbs (HP:0009823)2.03048625
78Aplasia of the phalanges of the hand (HP:0009802)2.03048625
79Dialeptic seizures (HP:0011146)2.02893597
80EEG with generalized epileptiform discharges (HP:0011198)2.02678255
81Urinary bladder sphincter dysfunction (HP:0002839)2.02582765
82Agitation (HP:0000713)2.01957615
83Micropenis (HP:0000054)2.01780421
84Dynein arm defect of respiratory motile cilia (HP:0012255)2.01339125
85Absent/shortened dynein arms (HP:0200106)2.01339125
86Dysdiadochokinesis (HP:0002075)2.00435758
87Morphological abnormality of the inner ear (HP:0011390)1.99549829
88Epileptiform EEG discharges (HP:0011182)1.99168618
89Cupped ear (HP:0000378)1.98918146
90Astrocytoma (HP:0009592)1.98752501
91Abnormality of the astrocytes (HP:0100707)1.98752501
92Nonprogressive disorder (HP:0003680)1.98421055
93Fetal akinesia sequence (HP:0001989)1.96035991
94Abolished electroretinogram (ERG) (HP:0000550)1.95916977
95Congenital primary aphakia (HP:0007707)1.95265663
96Truncal ataxia (HP:0002078)1.94863885
97Decreased testicular size (HP:0008734)1.94617287
98Abnormality of the septum pellucidum (HP:0007375)1.92917192
99Hypoplasia of the iris (HP:0007676)1.91892332
100Excessive salivation (HP:0003781)1.90858862
101Drooling (HP:0002307)1.90858862
102Abnormality of the musculature of the pelvis (HP:0001469)1.89988183
103Abnormality of the hip-girdle musculature (HP:0001445)1.89988183
104Colon cancer (HP:0003003)1.89148470
105Chronic hepatic failure (HP:0100626)1.87917907
106Nephrogenic diabetes insipidus (HP:0009806)1.87332494
107Atrophy/Degeneration involving motor neurons (HP:0007373)1.85119768
108Absence seizures (HP:0002121)1.85002864
109Shoulder girdle muscle weakness (HP:0003547)1.84878115
110Generalized tonic-clonic seizures (HP:0002069)1.84796650
111Humeroradial synostosis (HP:0003041)1.84672787
112Synostosis involving the elbow (HP:0003938)1.84672787
113Anteriorly placed anus (HP:0001545)1.83164931
114Congenital nonbullous ichthyosiform erythroderma (HP:0007479)1.83049023
115Thyroid-stimulating hormone excess (HP:0002925)1.83044977
116Decreased number of large peripheral myelinated nerve fibers (HP:0003387)1.83008692
117Decreased central vision (HP:0007663)1.82713994
118Decreased motor nerve conduction velocity (HP:0003431)1.81500373
119Split foot (HP:0001839)1.81116220
120Metabolic alkalosis (HP:0200114)1.80423020
121Abnormality of the lower motor neuron (HP:0002366)1.79761166
122Respiratory insufficiency due to defective ciliary clearance (HP:0200073)1.79372166
123Abnormality of salivation (HP:0100755)1.79120207
124Aqueductal stenosis (HP:0002410)1.79027715
125Megalencephaly (HP:0001355)1.78976689
126Bowel incontinence (HP:0002607)1.78183642
127Severe Myopia (HP:0011003)1.77795315
128Long clavicles (HP:0000890)1.77000980
129Pachygyria (HP:0001302)1.76992019
130Cerebral hypomyelination (HP:0006808)1.75629842
131Hypoplastic pelvis (HP:0008839)1.75600067
132Choroideremia (HP:0001139)1.75398526
133Lissencephaly (HP:0001339)1.75287531
134Increased circulating renin level (HP:0000848)1.74652626
135Pancreatic fibrosis (HP:0100732)1.73721953
136Glioma (HP:0009733)1.73341156
137Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.73277625
138Urinary urgency (HP:0000012)1.72707696
139Tubulointerstitial nephritis (HP:0001970)1.71818372
140Abnormal eating behavior (HP:0100738)1.71771037
141Abnormality of incisor morphology (HP:0011063)1.71035118
142Postaxial hand polydactyly (HP:0001162)1.70971604
143Spastic tetraplegia (HP:0002510)1.70204191
144Short foot (HP:0001773)1.69953652
145Abnormal large intestine physiology (HP:0012700)1.67670207
146Paraplegia (HP:0010550)1.66688079
147Limb hypertonia (HP:0002509)1.66117618
148Postural instability (HP:0002172)1.65317253
149Hypoplastic iliac wings (HP:0002866)1.65180384
150Aplasia/Hypoplasia of the lens (HP:0008063)1.64881883
151Narrow forehead (HP:0000341)1.64565251
152Neoplasm of the adrenal cortex (HP:0100641)1.64117441
153Morphological abnormality of the pyramidal tract (HP:0002062)1.63761764
154Hypomagnesemia (HP:0002917)1.63622027
155Hyperglycinemia (HP:0002154)1.63169682
156Specific learning disability (HP:0001328)1.62359111
157Mutism (HP:0002300)1.61738884
158Embryonal renal neoplasm (HP:0011794)1.61207215
159Limb dystonia (HP:0002451)1.60004035

Predicted kinase interactions (KEA)

RankGene SetZ-score
1STK393.82801858
2OXSR13.53616019
3CASK3.48097499
4WNK32.65853493
5TNIK2.65045299
6EPHA42.45090488
7PRPF4B2.42622238
8ERBB32.32597925
9DYRK32.25280498
10CDK192.24629194
11PKN12.13479318
12BCR2.08360163
13TRIM281.99728077
14MARK11.94365482
15NTRK31.86485046
16WNK11.77551318
17NEK61.76797410
18SGK4941.75238915
19SGK2231.75238915
20FRK1.69050221
21EPHB11.65992636
22PNCK1.52794681
23SRPK11.50007132
24MAP2K71.44356975
25MAPK131.42963483
26MAP2K41.42585110
27MAPKAPK51.38589116
28PAK61.36554415
29BRD41.36204154
30MAP3K41.35945012
31EIF2AK11.35938225
32FGFR21.35668159
33EPHA31.34584610
34PINK11.32994716
35CDC71.30817564
36CLK11.27114744
37CAMK2B1.26946194
38CSNK1A1L1.23497024
39STK161.22982913
40MAP3K131.22780503
41UHMK11.20682892
42AKT31.19376322
43BMPR21.18113349
44NTRK21.17879069
45CAMK1D1.17450204
46MAP4K21.17384691
47WNK41.16582020
48PLK41.16223837
49NTRK11.14043244
50FES1.11729607
51CDK51.11535025
52MKNK21.10782894
53FGR1.08980535
54CAMK1G1.06832726
55MUSK1.06697012
56CSNK1G21.05888789
57CSNK1G31.05232465
58PBK1.05042276
59ZAK1.03424403
60CAMK2D1.03001058
61PRKCH1.02588864
62FER1.02072497
63MKNK11.01991750
64STK38L1.00396689
65RPS6KA41.00103529
66ROCK20.98081301
67CAMK2A0.97983868
68BMPR1B0.96724948
69PLK20.94777050
70SGK20.94637507
71PRKCE0.92064143
72MAP3K90.89968765
73IRAK20.88130472
74INSRR0.88120199
75PRKD30.87797045
76PLK30.82940206
77MINK10.82783131
78DAPK20.82172704
79CSNK1G10.81695737
80PRKCQ0.80967851
81SCYL20.78007823
82ADRBK20.77652731
83CDK30.76268669
84RIPK40.75412683
85MARK20.75141625
86TAOK10.74225285
87MAP3K60.73954349
88BLK0.73823546
89PHKG10.73036497
90PHKG20.73036497
91ATM0.72604623
92KSR10.71963119
93CAMK40.70858480
94SGK10.70752262
95PLK10.68180261
96TYRO30.67391747
97ICK0.65222562
98CAMK2G0.64962417
99MAP3K50.64377340
100CSNK1E0.63704684
101DYRK1A0.61833588
102MAPK70.61825673
103SIK20.59586753
104STK110.59502117
105VRK10.59486496
106FYN0.58405357
107ATR0.58367339
108GRK10.58135986
109MET0.57943296
110IRAK40.57939983
111SGK30.57832752
112SIK30.57776190
113CDK180.57712232
114PDPK10.57183117
115CSNK1D0.56775446
116CDK140.56526162
117CDK150.56108635
118PRKAA10.55755537
119PRKD20.53708906
120DYRK1B0.53585149
121YES10.53504888
122PRKACB0.51688387
123PRKG10.51325910
124MST40.48692843
125PAK30.48527179
126CAMK10.48051161
127TAF10.47966142
128GRK70.47925586
129DYRK20.47780402
130PRKCG0.47458727
131PDK10.46464284
132CDK11A0.45530457
133PRKDC0.43417821
134PIK3CA0.43303142
135PRKCZ0.43249098
136ERBB40.43108204
137TXK0.42280299
138CAMKK20.42236144
139GSK3B0.41731924
140MAPK100.41522457
141TRPM70.41018314
142CDK20.40945385
143CDK10.40477444
144LIMK10.39711267
145TNK20.39390209
146CSNK1A10.39316421
147CCNB10.38420571
148EGFR0.35739700
149LATS10.34378190
150RPS6KA50.34182007
151RPS6KA30.33854564
152TTK0.31034067

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050332.71997040
2Terpenoid backbone biosynthesis_Homo sapiens_hsa009002.47954164
3Morphine addiction_Homo sapiens_hsa050322.26666764
4Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.22697063
5GABAergic synapse_Homo sapiens_hsa047272.22405022
6Glutamatergic synapse_Homo sapiens_hsa047242.20982314
7Ether lipid metabolism_Homo sapiens_hsa005652.15401619
8Steroid biosynthesis_Homo sapiens_hsa001002.04893171
9Circadian entrainment_Homo sapiens_hsa047131.98696887
10Synaptic vesicle cycle_Homo sapiens_hsa047211.96911807
11Olfactory transduction_Homo sapiens_hsa047401.82779049
12Oocyte meiosis_Homo sapiens_hsa041141.82423863
13Serotonergic synapse_Homo sapiens_hsa047261.81639714
14Axon guidance_Homo sapiens_hsa043601.79225399
15Long-term depression_Homo sapiens_hsa047301.78961941
16Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.77230160
17Fatty acid elongation_Homo sapiens_hsa000621.76626961
18Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.72777009
19Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.61962826
20Salivary secretion_Homo sapiens_hsa049701.60096674
21Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.59933760
22Fanconi anemia pathway_Homo sapiens_hsa034601.55445972
23mRNA surveillance pathway_Homo sapiens_hsa030151.52749537
24Butanoate metabolism_Homo sapiens_hsa006501.51364690
25Phototransduction_Homo sapiens_hsa047441.50357955
26Dopaminergic synapse_Homo sapiens_hsa047281.49257435
27Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.49075597
28Collecting duct acid secretion_Homo sapiens_hsa049661.48918696
29Cholinergic synapse_Homo sapiens_hsa047251.48373615
30Taste transduction_Homo sapiens_hsa047421.48081002
31Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.45816158
32Amphetamine addiction_Homo sapiens_hsa050311.45307686
33Mismatch repair_Homo sapiens_hsa034301.41920397
34Long-term potentiation_Homo sapiens_hsa047201.40336042
35Sphingolipid metabolism_Homo sapiens_hsa006001.39513593
36Cocaine addiction_Homo sapiens_hsa050301.39393565
37Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.35166817
38Basal transcription factors_Homo sapiens_hsa030221.32129137
39Gastric acid secretion_Homo sapiens_hsa049711.29974943
40Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.28498886
41Circadian rhythm_Homo sapiens_hsa047101.26834822
42Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051201.26339647
43Renin secretion_Homo sapiens_hsa049241.25145527
44SNARE interactions in vesicular transport_Homo sapiens_hsa041301.24303089
45Propanoate metabolism_Homo sapiens_hsa006401.22754172
46Insulin secretion_Homo sapiens_hsa049111.20435729
47Calcium signaling pathway_Homo sapiens_hsa040201.17022963
48Fatty acid biosynthesis_Homo sapiens_hsa000611.15577152
49Cell cycle_Homo sapiens_hsa041101.13323500
50Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.10780466
51Phosphatidylinositol signaling system_Homo sapiens_hsa040701.09877158
52Fatty acid metabolism_Homo sapiens_hsa012121.08803670
53Vibrio cholerae infection_Homo sapiens_hsa051101.08755002
54Rheumatoid arthritis_Homo sapiens_hsa053231.08621313
55Regulation of autophagy_Homo sapiens_hsa041401.08474061
56Regulation of lipolysis in adipocytes_Homo sapiens_hsa049231.05555711
57Aldosterone synthesis and secretion_Homo sapiens_hsa049251.05344921
58Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.03706770
59Oxytocin signaling pathway_Homo sapiens_hsa049211.03371106
60RNA transport_Homo sapiens_hsa030131.02594716
61Autoimmune thyroid disease_Homo sapiens_hsa053201.01214233
62Dorso-ventral axis formation_Homo sapiens_hsa043201.00088109
63Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.99975636
64Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.99947059
65Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.98933775
66cAMP signaling pathway_Homo sapiens_hsa040240.98791591
67Non-homologous end-joining_Homo sapiens_hsa034500.98120997
68Ovarian steroidogenesis_Homo sapiens_hsa049130.94388695
69Vascular smooth muscle contraction_Homo sapiens_hsa042700.94325763
70Sphingolipid signaling pathway_Homo sapiens_hsa040710.94210050
71Ras signaling pathway_Homo sapiens_hsa040140.91682465
72ErbB signaling pathway_Homo sapiens_hsa040120.91585436
73RNA degradation_Homo sapiens_hsa030180.90553139
74Phospholipase D signaling pathway_Homo sapiens_hsa040720.89319936
75GnRH signaling pathway_Homo sapiens_hsa049120.88609811
76Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.88404268
77Lysine degradation_Homo sapiens_hsa003100.88186813
78DNA replication_Homo sapiens_hsa030300.82513423
79Renal cell carcinoma_Homo sapiens_hsa052110.82069455
80Nucleotide excision repair_Homo sapiens_hsa034200.81077352
81Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.80687488
82Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.79575263
83MAPK signaling pathway_Homo sapiens_hsa040100.76814223
84Chemokine signaling pathway_Homo sapiens_hsa040620.76232223
85Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.75230043
86AMPK signaling pathway_Homo sapiens_hsa041520.73956497
87Gap junction_Homo sapiens_hsa045400.73850260
88Pancreatic secretion_Homo sapiens_hsa049720.73515943
89Peroxisome_Homo sapiens_hsa041460.72289544
90cGMP-PKG signaling pathway_Homo sapiens_hsa040220.72090470
91Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.71414791
92Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.71296490
93Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.70310809
94Choline metabolism in cancer_Homo sapiens_hsa052310.68488015
95Longevity regulating pathway - mammal_Homo sapiens_hsa042110.67464412
96Spliceosome_Homo sapiens_hsa030400.66703013
97Phagosome_Homo sapiens_hsa041450.66528738
98Colorectal cancer_Homo sapiens_hsa052100.66402862
99Hippo signaling pathway_Homo sapiens_hsa043900.66140432
100alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.65677807
101Linoleic acid metabolism_Homo sapiens_hsa005910.65424906
102Endocytosis_Homo sapiens_hsa041440.65121164
103Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.62786406
104Melanogenesis_Homo sapiens_hsa049160.61608245
105Vitamin B6 metabolism_Homo sapiens_hsa007500.60887242
106beta-Alanine metabolism_Homo sapiens_hsa004100.60186844
107Lysosome_Homo sapiens_hsa041420.59160162
108Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.59076533
109Inositol phosphate metabolism_Homo sapiens_hsa005620.58156261
110ABC transporters_Homo sapiens_hsa020100.57257990
111Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.55777300
112Homologous recombination_Homo sapiens_hsa034400.55201947
113B cell receptor signaling pathway_Homo sapiens_hsa046620.55052956
114Type II diabetes mellitus_Homo sapiens_hsa049300.55039269
115Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.54438279
116mTOR signaling pathway_Homo sapiens_hsa041500.53325199
117Protein export_Homo sapiens_hsa030600.52735102
118Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.52323854
119Dilated cardiomyopathy_Homo sapiens_hsa054140.51212216
120TGF-beta signaling pathway_Homo sapiens_hsa043500.51081149
121Glycerophospholipid metabolism_Homo sapiens_hsa005640.50942438
122Rap1 signaling pathway_Homo sapiens_hsa040150.49777065
123Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.48347826
124Mineral absorption_Homo sapiens_hsa049780.45938337
125Regulation of actin cytoskeleton_Homo sapiens_hsa048100.45916856
126Endometrial cancer_Homo sapiens_hsa052130.45845462
127Type I diabetes mellitus_Homo sapiens_hsa049400.45427766
128Estrogen signaling pathway_Homo sapiens_hsa049150.45113926
129Adherens junction_Homo sapiens_hsa045200.44963368
130Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.44189928
131Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.44031628
132African trypanosomiasis_Homo sapiens_hsa051430.44011598
133Glucagon signaling pathway_Homo sapiens_hsa049220.43447261
134Maturity onset diabetes of the young_Homo sapiens_hsa049500.42799176
135Vitamin digestion and absorption_Homo sapiens_hsa049770.42672030
136Tight junction_Homo sapiens_hsa045300.42623734
137Graft-versus-host disease_Homo sapiens_hsa053320.42461593
138Wnt signaling pathway_Homo sapiens_hsa043100.42252233
139Hedgehog signaling pathway_Homo sapiens_hsa043400.42067998
140Alcoholism_Homo sapiens_hsa050340.41659165
141Primary bile acid biosynthesis_Homo sapiens_hsa001200.40463790
142Salmonella infection_Homo sapiens_hsa051320.39190563
143Thyroid hormone synthesis_Homo sapiens_hsa049180.39065954
144Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.38791375
145Glioma_Homo sapiens_hsa052140.38259869
146T cell receptor signaling pathway_Homo sapiens_hsa046600.38021580
147Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.35813675

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »