TXNL4B

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1respiratory chain complex IV assembly (GO:0008535)4.69245905
2proteasome assembly (GO:0043248)4.58168307
3presynaptic membrane assembly (GO:0097105)4.26916850
4cytochrome complex assembly (GO:0017004)4.09489451
5postsynaptic membrane organization (GO:0001941)4.09343213
6negative regulation of retinoic acid receptor signaling pathway (GO:0048387)4.04256031
7mannosylation (GO:0097502)4.01341494
8polyamine biosynthetic process (GO:0006596)4.00146715
9protein localization to cilium (GO:0061512)3.98670250
10DNA deamination (GO:0045006)3.88981455
11sympathetic nervous system development (GO:0048485)3.85028733
12regulation of retinoic acid receptor signaling pathway (GO:0048385)3.60108066
13presynaptic membrane organization (GO:0097090)3.55636583
14rRNA modification (GO:0000154)3.54106055
15ribosomal small subunit assembly (GO:0000028)3.42432888
16regulation of pigment cell differentiation (GO:0050932)3.41433050
17thrombin receptor signaling pathway (GO:0070493)3.34587523
18facial nerve structural organization (GO:0021612)3.34474549
19rRNA methylation (GO:0031167)3.27941006
20polyamine metabolic process (GO:0006595)3.26703778
21protein heterotetramerization (GO:0051290)3.26283119
22lymphoid progenitor cell differentiation (GO:0002320)3.24477402
23GPI anchor biosynthetic process (GO:0006506)3.21839869
24superoxide anion generation (GO:0042554)3.17653461
25negative regulation of transcription by competitive promoter binding (GO:0010944)3.06340124
26negative regulation of thymocyte apoptotic process (GO:0070244)3.04571200
27neurofilament cytoskeleton organization (GO:0060052)3.03885297
28protein complex biogenesis (GO:0070271)2.99845011
29cytidine metabolic process (GO:0046087)2.99413168
30cytidine catabolic process (GO:0006216)2.99413168
31cytidine deamination (GO:0009972)2.99413168
32DNA catabolic process, exonucleolytic (GO:0000738)2.99146560
33positive regulation of cellular amine metabolic process (GO:0033240)2.97746234
34termination of RNA polymerase III transcription (GO:0006386)2.93361539
35transcription elongation from RNA polymerase III promoter (GO:0006385)2.93361539
36neutrophil activation (GO:0042119)2.93257757
37establishment of protein localization to mitochondrial membrane (GO:0090151)2.92624974
38L-methionine biosynthetic process from methylthioadenosine (GO:0019509)2.90276595
39negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)2.88843352
40dolichol-linked oligosaccharide biosynthetic process (GO:0006488)2.88736622
41mitochondrial electron transport, NADH to ubiquinone (GO:0006120)2.88036583
42regulation of platelet activation (GO:0010543)2.85599858
43androgen biosynthetic process (GO:0006702)2.83662817
44NADH dehydrogenase complex assembly (GO:0010257)2.83435186
45mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.83435186
46mitochondrial respiratory chain complex I assembly (GO:0032981)2.83435186
47signal peptide processing (GO:0006465)2.82235014
48G-protein coupled purinergic nucleotide receptor signaling pathway (GO:0035589)2.82109661
49chaperone-mediated protein transport (GO:0072321)2.81871258
50centriole assembly (GO:0098534)2.81286019
51regulation of platelet aggregation (GO:0090330)2.80927449
52positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)2.79707753
53centriole replication (GO:0007099)2.78856374
54histone mRNA metabolic process (GO:0008334)2.77506888
55cellular biogenic amine biosynthetic process (GO:0042401)2.76693484
56GPI anchor metabolic process (GO:0006505)2.76575250
57male meiosis (GO:0007140)2.76270124
58neuronal action potential propagation (GO:0019227)2.76098253
59dopamine transport (GO:0015872)2.75811468
60microtubule depolymerization (GO:0007019)2.74392499
61regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)2.74219019
62C-terminal protein lipidation (GO:0006501)2.73899350
63granulocyte activation (GO:0036230)2.73261373
64protein neddylation (GO:0045116)2.73188013
65positive regulation of mast cell activation (GO:0033005)2.72753454
66negative regulation of execution phase of apoptosis (GO:1900118)2.71914918
67purinergic nucleotide receptor signaling pathway (GO:0035590)2.71398660
68positive regulation of cAMP-mediated signaling (GO:0043950)2.70759266
69deoxyribonucleoside monophosphate metabolic process (GO:0009162)2.70531511
70negative regulation of heart rate (GO:0010459)2.69428589
71cellular response to arsenic-containing substance (GO:0071243)2.68436116
72DNA double-strand break processing (GO:0000729)2.66487725
73anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:02.64457318
74negative regulation of ligase activity (GO:0051352)2.64129338
75negative regulation of ubiquitin-protein transferase activity (GO:0051444)2.64129338
76protein K11-linked ubiquitination (GO:0070979)2.63874630
77intrinsic apoptotic signaling pathway in response to oxidative stress (GO:0008631)2.62597239
78pyrimidine deoxyribonucleotide metabolic process (GO:0009219)2.62279545
79mitochondrial respiratory chain complex assembly (GO:0033108)2.62093324
80DNA ligation (GO:0006266)2.61459209
81positive regulation of endothelial cell differentiation (GO:0045603)2.60943519
82DNA demethylation (GO:0080111)2.59778489
83DNA-dependent DNA replication (GO:0006261)2.59589561
84platelet dense granule organization (GO:0060155)2.58557531
85positive regulation of ubiquitin-protein transferase activity (GO:0051443)2.58396437
86peripheral nervous system neuron development (GO:0048935)2.57986687
87regulation of cellular amino acid metabolic process (GO:0006521)2.56674197
88mitochondrial calcium ion transport (GO:0006851)2.56649814
89amine biosynthetic process (GO:0009309)2.56060159
90GMP metabolic process (GO:0046037)2.55291933
91nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)2.55283640
92exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 2.54478604
93positive regulation of ligase activity (GO:0051351)2.54269838
94developmental pigmentation (GO:0048066)2.53008455
95intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)2.52629314
96signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)2.52629314
97blood coagulation, intrinsic pathway (GO:0007597)2.52518062
98purine-containing compound salvage (GO:0043101)2.51758280
99methionine metabolic process (GO:0006555)2.51118405
100regulation of chronic inflammatory response (GO:0002676)2.50558034
101CENP-A containing nucleosome assembly (GO:0034080)2.49881767
102methionine biosynthetic process (GO:0009086)2.49553895
103positive regulation of granulocyte differentiation (GO:0030854)2.49132873
104negative regulation of norepinephrine secretion (GO:0010700)2.49009035
105antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:2.47673875
106GDP-mannose metabolic process (GO:0019673)2.47649888
107enteric nervous system development (GO:0048484)2.47052700
108GTP biosynthetic process (GO:0006183)2.46937420
109keratinocyte development (GO:0003334)2.46911163
110deoxyribonucleoside diphosphate metabolic process (GO:0009186)2.46252746
111negative regulation of T-helper cell differentiation (GO:0045623)2.46195637
112negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371)2.46195637
113C-terminal protein amino acid modification (GO:0018410)2.46065320
114piRNA metabolic process (GO:0034587)2.45943727
115regulation of cilium movement (GO:0003352)2.45654724
116ribosomal small subunit biogenesis (GO:0042274)2.44835554
117intraciliary transport (GO:0042073)2.44796758
118adenosine receptor signaling pathway (GO:0001973)2.43933314
119neutrophil activation involved in immune response (GO:0002283)2.43868232
120generation of neurons (GO:0048699)2.42149907
121regulation of T-helper 1 cell differentiation (GO:0045625)2.41248859
122detection of bacterium (GO:0016045)2.40874809
123viral protein processing (GO:0019082)2.40442652
124cranial nerve structural organization (GO:0021604)2.40201528
125negative regulation of type 2 immune response (GO:0002829)2.40051145
126signal transduction involved in DNA damage checkpoint (GO:0072422)2.39841519
127signal transduction involved in DNA integrity checkpoint (GO:0072401)2.39841519
128axonemal dynein complex assembly (GO:0070286)2.38907822
129axoneme assembly (GO:0035082)2.38871773
130regulation of immunoglobulin secretion (GO:0051023)2.38527644
131mature B cell differentiation involved in immune response (GO:0002313)2.38284533
132positive regulation of mitochondrial calcium ion concentration (GO:0051561)2.37877711
133iron-sulfur cluster assembly (GO:0016226)2.37600515
134metallo-sulfur cluster assembly (GO:0031163)2.37600515
135signal transduction involved in cell cycle checkpoint (GO:0072395)2.37510625
136tRNA methylation (GO:0030488)2.37210488
137protein deneddylation (GO:0000338)2.36844399
138reactive oxygen species biosynthetic process (GO:1903409)2.35964575
139cullin deneddylation (GO:0010388)2.35147818
1402-deoxyribonucleotide biosynthetic process (GO:0009265)2.35026718
141deoxyribose phosphate biosynthetic process (GO:0046385)2.35026718
142meiosis I (GO:0007127)2.33970705
143regulation of double-strand break repair via homologous recombination (GO:0010569)2.33881047
144regulation of integrin-mediated signaling pathway (GO:2001044)2.33345355
145deoxyribonucleoside triphosphate metabolic process (GO:0009200)2.32996131
146response to folic acid (GO:0051593)2.32965994
147pyrimidine ribonucleoside catabolic process (GO:0046133)2.32940898
148antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590)2.32349417
149negative regulation of homotypic cell-cell adhesion (GO:0034111)2.32076704
150positive regulation of macrophage differentiation (GO:0045651)2.31921681
151preassembly of GPI anchor in ER membrane (GO:0016254)2.31750266
152pyrimidine deoxyribonucleotide catabolic process (GO:0009223)2.30804713
153regulation of regulatory T cell differentiation (GO:0045589)2.30354682
154L-methionine biosynthetic process (GO:0071265)2.29823443
155amino acid salvage (GO:0043102)2.29823443
156L-methionine salvage (GO:0071267)2.29823443
157single strand break repair (GO:0000012)2.29810261
158pyrimidine nucleoside catabolic process (GO:0046135)2.28548211
159mitochondrial DNA replication (GO:0006264)2.28287518
160histone mRNA catabolic process (GO:0071044)2.27926095
161mesonephros development (GO:0001823)2.25591755
162nucleoside diphosphate catabolic process (GO:0009134)2.24454415
163guanosine-containing compound biosynthetic process (GO:1901070)2.23747277
164epithelial cilium movement (GO:0003351)2.22324442
165tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)2.21664769
166RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)2.21664769
167adenosine metabolic process (GO:0046085)2.21642626
1682-deoxyribonucleotide metabolic process (GO:0009394)2.20245673
169negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515)2.20202650
170multicellular organism reproduction (GO:0032504)2.19116327
171DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:002.18857704
172sequestering of actin monomers (GO:0042989)2.18366193
173acrosome reaction (GO:0007340)2.17281713
174signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)2.15044322
175signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)2.15044322
176signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)2.15044322
177respiratory burst (GO:0045730)2.14590310
1787-methylguanosine RNA capping (GO:0009452)2.14352871

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human4.58743223
2SOX9_22984422_ChIP-ChIP_TESTIS_Rat4.42333244
3TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse3.41218481
4CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human3.15942555
5E2F7_22180533_ChIP-Seq_HELA_Human2.80230365
6ELF1_17652178_ChIP-ChIP_JURKAT_Human2.79604241
7ZFP57_27257070_Chip-Seq_ESCs_Mouse2.57123369
8E2F4_17652178_ChIP-ChIP_JURKAT_Human2.55549907
9GBX2_23144817_ChIP-Seq_PC3_Human2.53483314
10TAF15_26573619_Chip-Seq_HEK293_Human2.48951619
11NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.46382927
12PCGF2_27294783_Chip-Seq_ESCs_Mouse2.44498112
13CREB1_15753290_ChIP-ChIP_HEK293T_Human2.39049449
14GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.35084693
15FLI1_27457419_Chip-Seq_LIVER_Mouse2.34383555
16* KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.29309562
17BMI1_23680149_ChIP-Seq_NPCS_Mouse2.16314894
18HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.14286992
19* FOXP3_21729870_ChIP-Seq_TREG_Human2.11103108
20PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse2.08150965
21DCP1A_22483619_ChIP-Seq_HELA_Human2.04178578
22GATA1_22025678_ChIP-Seq_K562_Human1.94609407
23* JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.93998171
24FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.92854387
25* GABP_17652178_ChIP-ChIP_JURKAT_Human1.88052333
26MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.85835673
27LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.85402570
28IRF1_19129219_ChIP-ChIP_H3396_Human1.85170755
29SRF_21415370_ChIP-Seq_HL-1_Mouse1.79422750
30* EST1_17652178_ChIP-ChIP_JURKAT_Human1.76065019
31BP1_19119308_ChIP-ChIP_Hs578T_Human1.74540198
32VDR_22108803_ChIP-Seq_LS180_Human1.72555105
33IGF1R_20145208_ChIP-Seq_DFB_Human1.70628452
34POU3F2_20337985_ChIP-ChIP_501MEL_Human1.69052643
35PADI4_21655091_ChIP-ChIP_MCF-7_Human1.67975333
36RNF2_27304074_Chip-Seq_NSC_Mouse1.67015240
37MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.65151024
38IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.60738208
39NFE2_27457419_Chip-Seq_LIVER_Mouse1.59601681
40CBX2_27304074_Chip-Seq_ESCs_Mouse1.58019594
41GABP_19822575_ChIP-Seq_HepG2_Human1.57475966
42SUZ12_27294783_Chip-Seq_NPCs_Mouse1.57144209
43STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.50993736
44MYC_18555785_ChIP-Seq_MESCs_Mouse1.47782656
45P300_19829295_ChIP-Seq_ESCs_Human1.47086820
46IRF8_22096565_ChIP-ChIP_GC-B_Human1.46992789
47NOTCH1_21737748_ChIP-Seq_TLL_Human1.46543558
48IRF8_21731497_ChIP-ChIP_J774_Mouse1.45506077
49JARID2_20064375_ChIP-Seq_MESCs_Mouse1.45273373
50PCGF2_27294783_Chip-Seq_NPCs_Mouse1.43063144
51STAT3_18555785_Chip-Seq_ESCs_Mouse1.41527305
52ZNF274_21170338_ChIP-Seq_K562_Hela1.41055407
53RUNX1_27457419_Chip-Seq_LIVER_Mouse1.40363218
54TAL1_26923725_Chip-Seq_HPCs_Mouse1.39062502
55EZH2_27294783_Chip-Seq_NPCs_Mouse1.38773231
56SUZ12_18555785_Chip-Seq_ESCs_Mouse1.37785909
57P53_22387025_ChIP-Seq_ESCs_Mouse1.37180076
58MYC_19030024_ChIP-ChIP_MESCs_Mouse1.36626397
59PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.36144725
60EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.36108174
61EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.36040231
62TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.34793924
63E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.33689453
64IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.33276374
65THAP11_20581084_ChIP-Seq_MESCs_Mouse1.32748900
66NANOG_18555785_Chip-Seq_ESCs_Mouse1.30074966
67TTF2_22483619_ChIP-Seq_HELA_Human1.29864021
68* FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.29851390
69* HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.29471278
70EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.28756847
71NELFA_20434984_ChIP-Seq_ESCs_Mouse1.28462556
72EZH2_27304074_Chip-Seq_ESCs_Mouse1.28439466
73FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.27859309
74* SPI1_23547873_ChIP-Seq_NB4_Human1.27608505
75* YY1_21170310_ChIP-Seq_MESCs_Mouse1.27010300
76NMYC_18555785_Chip-Seq_ESCs_Mouse1.26983122
77CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.26768234
78ERG_20887958_ChIP-Seq_HPC-7_Mouse1.26318301
79P300_18555785_Chip-Seq_ESCs_Mouse1.26105124
80EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.26011337
81HTT_18923047_ChIP-ChIP_STHdh_Human1.25387415
82GATA3_26560356_Chip-Seq_TH2_Human1.25038292
83E2F1_18555785_ChIP-Seq_MESCs_Mouse1.23509063
84RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.21879359
85MYC_18358816_ChIP-ChIP_MESCs_Mouse1.21715907
86* E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.20441294
87CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.19646090
88CMYC_18555785_Chip-Seq_ESCs_Mouse1.18134634
89TFEB_21752829_ChIP-Seq_HELA_Human1.17939776
90E2F1_18555785_Chip-Seq_ESCs_Mouse1.16513863
91PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.16417629
92HOXB4_20404135_ChIP-ChIP_EML_Mouse1.16228413
93HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.16065509
94* FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.15937927
95* SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.15091427
96TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.14291370
97SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.14102531
98SOX2_18555785_Chip-Seq_ESCs_Mouse1.13201624
99MYB_21317192_ChIP-Seq_ERMYB_Mouse1.12493118
100SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.10897545
101CTBP1_25329375_ChIP-Seq_LNCAP_Human1.10795220
102FUS_26573619_Chip-Seq_HEK293_Human1.10669952
103OCT4_18555785_Chip-Seq_ESCs_Mouse1.10202757
104SMAD1_18555785_Chip-Seq_ESCs_Mouse1.09334254
105PU1_27457419_Chip-Seq_LIVER_Mouse1.09109375
106KLF4_18555785_Chip-Seq_ESCs_Mouse1.08655675
107EED_16625203_ChIP-ChIP_MESCs_Mouse1.08008912
108CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.07971172
109* SALL4_22934838_ChIP-ChIP_CD34+_Human1.07793141
110CRX_20693478_ChIP-Seq_RETINA_Mouse1.07272088
111SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.05788219
112JARID2_20075857_ChIP-Seq_MESCs_Mouse1.05228764
113FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.04272519
114RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.03944413
115KDM2B_26808549_Chip-Seq_REH_Human1.02251294
116ZFX_18555785_Chip-Seq_ESCs_Mouse1.01346931
117KAP1_22055183_ChIP-Seq_ESCs_Mouse1.00590316
118VDR_23849224_ChIP-Seq_CD4+_Human1.00305548
119MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.00168668
120PPARD_23208498_ChIP-Seq_MDA-MB-231_Human1.00071265
121* SPI1_22096565_ChIP-ChIP_GC-B_Mouse0.99994247
122CTBP2_25329375_ChIP-Seq_LNCAP_Human0.99957956
123ESRRB_18555785_Chip-Seq_ESCs_Mouse0.99476393
124TP53_22573176_ChIP-Seq_HFKS_Human0.99362562
125SCL_19346495_ChIP-Seq_HPC-7_Human0.99328134
126MYCN_18555785_ChIP-Seq_MESCs_Mouse0.99105512
127RUNX1_20887958_ChIP-Seq_HPC-7_Mouse0.98780921
128CTCF_18555785_Chip-Seq_ESCs_Mouse0.97929753
129CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.97561936
130MYBL2_22936984_ChIP-ChIP_MESCs_Mouse0.97406227
131STAT1_17558387_ChIP-Seq_HELA_Human0.97317552
132ELK1_19687146_ChIP-ChIP_HELA_Human0.96806395
133ETS1_20019798_ChIP-Seq_JURKAT_Human0.96476883
134POU5F1_16153702_ChIP-ChIP_HESCs_Human0.95826231
135* FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse0.95708560
136EWS_26573619_Chip-Seq_HEK293_Human0.95704079
137STAT4_19710469_ChIP-ChIP_TH1__Mouse0.95246727
138LMO2_20887958_ChIP-Seq_HPC-7_Mouse0.95100990
139MYC_18940864_ChIP-ChIP_HL60_Human0.95019105
140HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.94895761
141CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.93603537
142AR_20517297_ChIP-Seq_VCAP_Human0.93509291
143KDM5A_27292631_Chip-Seq_BREAST_Human0.92758710
144MEIS1_20887958_ChIP-Seq_HPC-7_Mouse0.92464795
145ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.92058897
146PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human0.92034128
147SOX2_19829295_ChIP-Seq_ESCs_Human0.91855398
148NANOG_19829295_ChIP-Seq_ESCs_Human0.91855398
149MYB_26560356_Chip-Seq_TH2_Human0.86866061
150MYC_19079543_ChIP-ChIP_MESCs_Mouse0.86526605
151ELK1_22589737_ChIP-Seq_MCF10A_Human0.85891638
152XRN2_22483619_ChIP-Seq_HELA_Human0.85886157
153FOXA1_25329375_ChIP-Seq_VCAP_Human0.85502326
154FOXA1_27270436_Chip-Seq_PROSTATE_Human0.85502326
155YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse0.85332224
156SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.85093504
157ER_23166858_ChIP-Seq_MCF-7_Human0.83155339
158EGR1_23403033_ChIP-Seq_LIVER_Mouse0.83086258

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005464_abnormal_platelet_physiology5.08947498
2MP0003136_yellow_coat_color3.75463209
3MP0001188_hyperpigmentation3.72481393
4MP0009379_abnormal_foot_pigmentation3.58579628
5MP0005409_darkened_coat_color3.44544242
6MP0006292_abnormal_olfactory_placode3.37365836
7MP0001986_abnormal_taste_sensitivity3.03493534
8MP0003880_abnormal_central_pattern2.96655165
9MP0000015_abnormal_ear_pigmentation2.95199414
10MP0008004_abnormal_stomach_pH2.82225667
11MP0004381_abnormal_hair_follicle2.72916377
12MP0005174_abnormal_tail_pigmentation2.67336180
13MP0000372_irregular_coat_pigmentation2.55780496
14MP0002876_abnormal_thyroid_physiology2.33248242
15MP0005075_abnormal_melanosome_morpholog2.25567741
16MP0010094_abnormal_chromosome_stability2.20498517
17MP0009785_altered_susceptibility_to2.02250461
18MP0006036_abnormal_mitochondrial_physio2.00469890
19MP0002751_abnormal_autonomic_nervous2.00210165
20MP0006035_abnormal_mitochondrial_morpho1.93378655
21MP0001984_abnormal_olfaction1.92684199
22MP0008260_abnormal_autophagy1.90689113
23MP0006276_abnormal_autonomic_nervous1.89846554
24MP0003724_increased_susceptibility_to1.88372852
25MP0002148_abnormal_hypersensitivity_rea1.80640629
26MP0000465_gastrointestinal_hemorrhage1.77709727
27MP0002638_abnormal_pupillary_reflex1.75071822
28MP0002735_abnormal_chemical_nociception1.74391124
29MP0008057_abnormal_DNA_replication1.69831185
30MP0003656_abnormal_erythrocyte_physiolo1.68937420
31MP0005410_abnormal_fertilization1.68198293
32MP0008872_abnormal_physiological_respon1.66239632
33MP0001905_abnormal_dopamine_level1.64005298
34MP0001835_abnormal_antigen_presentation1.61343258
35MP0004510_myositis1.59159648
36MP0002095_abnormal_skin_pigmentation1.58849256
37MP0000358_abnormal_cell_content/1.57582541
38MP0005171_absent_coat_pigmentation1.56120859
39MP0000343_altered_response_to1.54865534
40MP0005671_abnormal_response_to1.54623152
41MP0008789_abnormal_olfactory_epithelium1.53412454
42MP0002398_abnormal_bone_marrow1.51156139
43MP0001968_abnormal_touch/_nociception1.47253708
44MP0000566_synostosis1.46512650
45MP0008058_abnormal_DNA_repair1.45528035
46MP0002160_abnormal_reproductive_system1.43438852
47MP0004147_increased_porphyrin_level1.42883229
48MP0009764_decreased_sensitivity_to1.42678476
49MP0004957_abnormal_blastocyst_morpholog1.39287373
50MP0003077_abnormal_cell_cycle1.31630400
51MP0003111_abnormal_nucleus_morphology1.29871339
52MP0003693_abnormal_embryo_hatching1.28482422
53MP0002736_abnormal_nociception_after1.28398760
54MP0002272_abnormal_nervous_system1.28256780
55MP0000681_abnormal_thyroid_gland1.27970739
56MP0002102_abnormal_ear_morphology1.26913818
57MP0003718_maternal_effect1.26344316
58MP0000689_abnormal_spleen_morphology1.26103498
59MP0008932_abnormal_embryonic_tissue1.25297391
60MP0003828_pulmonary_edema1.25213177
61MP0001790_abnormal_immune_system1.24424432
62MP0005387_immune_system_phenotype1.24424432
63MP0002277_abnormal_respiratory_mucosa1.23729433
64MP0004142_abnormal_muscle_tone1.23726880
65MP0002132_abnormal_respiratory_system1.23554605
66MP0005025_abnormal_response_to1.23436211
67MP0003786_premature_aging1.21763377
68MP0009333_abnormal_splenocyte_physiolog1.21159203
69MP0005646_abnormal_pituitary_gland1.18794246
70MP0003879_abnormal_hair_cell1.17986698
71MP0005645_abnormal_hypothalamus_physiol1.14172533
72MP0000049_abnormal_middle_ear1.14002486
73MP0005000_abnormal_immune_tolerance1.12967680
74MP0004782_abnormal_surfactant_physiolog1.12334417
75MP0001929_abnormal_gametogenesis1.10844502
76MP0002722_abnormal_immune_system1.09587661
77MP0003195_calcinosis1.09387321
78MP0010155_abnormal_intestine_physiology1.09310217
79MP0002419_abnormal_innate_immunity1.09293248
80MP0002429_abnormal_blood_cell1.09157281
81MP0005499_abnormal_olfactory_system1.08642688
82MP0005394_taste/olfaction_phenotype1.08642688
83MP0000026_abnormal_inner_ear1.07991427
84MP0000716_abnormal_immune_system1.07183393
85MP0002210_abnormal_sex_determination1.06519597
86MP0003763_abnormal_thymus_physiology1.04413566
87MP0002184_abnormal_innervation1.03573818
88MP0001845_abnormal_inflammatory_respons1.02835625
89MP0000230_abnormal_systemic_arterial1.01223021
90MP0003221_abnormal_cardiomyocyte_apopto1.01168424
91MP0003938_abnormal_ear_development1.00037931
92MP0005058_abnormal_lysosome_morphology0.99841101
93MP0009763_increased_sensitivity_to0.99753328
94MP0008995_early_reproductive_senescence0.99726169
95MP0004270_analgesia0.99616632
96MP0002067_abnormal_sensory_capabilities0.98528202
97MP0000631_abnormal_neuroendocrine_gland0.98519678
98MP0001529_abnormal_vocalization0.98395464
99MP0002734_abnormal_mechanical_nocicepti0.96855232
100MP0009765_abnormal_xenobiotic_induced0.96290517
101MP0001963_abnormal_hearing_physiology0.96131440
102MP0003646_muscle_fatigue0.96123585
103MP0006082_CNS_inflammation0.95971134
104MP0001542_abnormal_bone_strength0.95546834
105MP0009046_muscle_twitch0.94629821
106MP0002177_abnormal_outer_ear0.94431371
107MP0003303_peritoneal_inflammation0.94036968
108MP0005389_reproductive_system_phenotype0.91970166
109MP0002723_abnormal_immune_serum0.91806851
110MP0000703_abnormal_thymus_morphology0.91751765
111MP0009745_abnormal_behavioral_response0.91589347
112MP0002009_preneoplasia0.91350093
113MP0005408_hypopigmentation0.91158980
114MP0003011_delayed_dark_adaptation0.90981176
115MP0002405_respiratory_system_inflammati0.90939478
116MP0002420_abnormal_adaptive_immunity0.89809938
117MP0003186_abnormal_redox_activity0.89523308
118MP0001819_abnormal_immune_cell0.88074626
119MP0003315_abnormal_perineum_morphology0.87615078
120MP0005310_abnormal_salivary_gland0.87380872
121MP0001970_abnormal_pain_threshold0.86587832
122MP0003436_decreased_susceptibility_to0.85980697
123MP0001919_abnormal_reproductive_system0.84338453
124MP0009697_abnormal_copulation0.82682362
125MP0005379_endocrine/exocrine_gland_phen0.82515373
126MP0001853_heart_inflammation0.81004150
127MP0005084_abnormal_gallbladder_morpholo0.80818772
128MP0002452_abnormal_antigen_presenting0.80800065
129MP0002019_abnormal_tumor_incidence0.79326561
130MP0002752_abnormal_somatic_nervous0.78894659
131MP0001486_abnormal_startle_reflex0.78521563
132MP0003950_abnormal_plasma_membrane0.78200768
133MP0002163_abnormal_gland_morphology0.78015463
134MP0006054_spinal_hemorrhage0.77745071
135MP0001764_abnormal_homeostasis0.77572445
136MP0000653_abnormal_sex_gland0.77505640
137MP0003638_abnormal_response/metabolism_0.77051319
138MP0001800_abnormal_humoral_immune0.77032942
139MP0001502_abnormal_circadian_rhythm0.76450385
140MP0003698_abnormal_male_reproductive0.76106803
141MP0008873_increased_physiological_sensi0.75870488
142MP0005266_abnormal_metabolism0.75012629
143MP0002090_abnormal_vision0.72832446
144MP0000313_abnormal_cell_death0.72618412
145MP0005397_hematopoietic_system_phenotyp0.72316363
146MP0001545_abnormal_hematopoietic_system0.72316363
147MP0008875_abnormal_xenobiotic_pharmacok0.71963267
148MP0002557_abnormal_social/conspecific_i0.70466571
149MP0008007_abnormal_cellular_replicative0.70359173
150MP0003806_abnormal_nucleotide_metabolis0.69245268
151MP0008877_abnormal_DNA_methylation0.68760195
152MP0008569_lethality_at_weaning0.68417500
153MP0000685_abnormal_immune_system0.67260849
154MP0004742_abnormal_vestibular_system0.67258803

Predicted human phenotypes

RankGene SetZ-score
1Petechiae (HP:0000967)6.14952035
2Prolonged bleeding time (HP:0003010)5.90691982
3Type I transferrin isoform profile (HP:0003642)5.36513715
4Menorrhagia (HP:0000132)4.84930293
5Hypothermia (HP:0002045)4.82614781
6Purpura (HP:0000979)4.78446704
7Reduced antithrombin III activity (HP:0001976)4.70364367
8Increased mean platelet volume (HP:0011877)4.41607695
9Abnormal platelet volume (HP:0011876)4.17375578
10Epistaxis (HP:0000421)3.74699709
11Abnormal glycosylation (HP:0012345)3.71255131
12Abnormal isoelectric focusing of serum transferrin (HP:0003160)3.71255131
13Abnormal protein N-linked glycosylation (HP:0012347)3.71255131
14Abnormal protein glycosylation (HP:0012346)3.71255131
15Gingival bleeding (HP:0000225)3.48993970
16Hepatocellular necrosis (HP:0001404)3.31709927
17Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)3.29452902
18Dyschromatopsia (HP:0007641)3.23805870
19Impaired platelet aggregation (HP:0003540)3.21191442
20Abnormal platelet function (HP:0011869)3.21191442
213-Methylglutaconic aciduria (HP:0003535)3.19647987
22Absent rod-and cone-mediated responses on ERG (HP:0007688)3.15387080
23Muscle abnormality related to mitochondrial dysfunction (HP:0003800)3.11569562
24Mitochondrial inheritance (HP:0001427)3.06310198
25Renal Fanconi syndrome (HP:0001994)3.02662911
26Increased hepatocellular lipid droplets (HP:0006565)2.95263937
27Upper limb muscle weakness (HP:0003484)2.92954352
28Absent/shortened dynein arms (HP:0200106)2.88408642
29Dynein arm defect of respiratory motile cilia (HP:0012255)2.88408642
30Thyroid-stimulating hormone excess (HP:0002925)2.88401372
31Abnormal number of erythroid precursors (HP:0012131)2.86385071
32Acute necrotizing encephalopathy (HP:0006965)2.85995270
33Abnormality of cells of the erythroid lineage (HP:0012130)2.81661296
34Hepatic necrosis (HP:0002605)2.79510729
35Nonprogressive disorder (HP:0003680)2.77227257
36Hyperlipoproteinemia (HP:0010980)2.77195165
37Type 2 muscle fiber atrophy (HP:0003554)2.75732554
38True hermaphroditism (HP:0010459)2.69093206
39Abnormal respiratory epithelium morphology (HP:0012253)2.65543547
40Abnormal respiratory motile cilium morphology (HP:0005938)2.65543547
41Increased IgM level (HP:0003496)2.63978578
42Respiratory insufficiency due to defective ciliary clearance (HP:0200073)2.62680432
43Lipid accumulation in hepatocytes (HP:0006561)2.59008101
44Severe visual impairment (HP:0001141)2.57208345
45Abnormality of lateral ventricle (HP:0030047)2.53898783
46Increased CSF lactate (HP:0002490)2.51818070
47Abnormal mitochondria in muscle tissue (HP:0008316)2.51054519
48Abnormality of secondary sexual hair (HP:0009888)2.47371262
49Abnormality of the axillary hair (HP:0100134)2.47371262
50Generalized aminoaciduria (HP:0002909)2.43576797
51Nausea (HP:0002018)2.43527866
52Acanthocytosis (HP:0001927)2.43444067
53Optic disc pallor (HP:0000543)2.42645954
54Abnormal ciliary motility (HP:0012262)2.40028035
55Poikilocytosis (HP:0004447)2.39035937
56Parakeratosis (HP:0001036)2.37778373
57Exertional dyspnea (HP:0002875)2.35527344
58Albinism (HP:0001022)2.33663657
59Aplastic anemia (HP:0001915)2.28780380
60Abnormal spermatogenesis (HP:0008669)2.27928241
61Muscle fiber atrophy (HP:0100295)2.25136538
62Abnormality of renal resorption (HP:0011038)2.24284112
63Abnormality of magnesium homeostasis (HP:0004921)2.24161775
64Progressive macrocephaly (HP:0004481)2.23555357
65Split foot (HP:0001839)2.22200393
66Abnormal rod and cone electroretinograms (HP:0008323)2.21240851
67Abnormal respiratory motile cilium physiology (HP:0012261)2.21223020
68Pancreatic fibrosis (HP:0100732)2.20927586
69Anhidrosis (HP:0000970)2.20682899
70Pancytopenia (HP:0001876)2.19035882
71Degeneration of anterior horn cells (HP:0002398)2.15229705
72Abnormality of the anterior horn cell (HP:0006802)2.15229705
73Tinnitus (HP:0000360)2.14599524
74Recurrent abscess formation (HP:0002722)2.14370175
75Conjunctival telangiectasia (HP:0000524)2.13681859
76Congenital nonbullous ichthyosiform erythroderma (HP:0007479)2.11619124
77Attenuation of retinal blood vessels (HP:0007843)2.11206712
78Respiratory difficulties (HP:0002880)2.10553196
79Aplasia/Hypoplasia of the sacrum (HP:0008517)2.10404853
80Birth length less than 3rd percentile (HP:0003561)2.08032468
81Abnormality of the vasculature of the conjunctiva (HP:0008054)2.07996163
82Obstructive lung disease (HP:0006536)2.06227348
83Chronic obstructive pulmonary disease (HP:0006510)2.06227348
84Focal motor seizures (HP:0011153)2.05647084
85IgG deficiency (HP:0004315)2.05573268
86Acute encephalopathy (HP:0006846)2.05317196
87Microvesicular hepatic steatosis (HP:0001414)2.04448865
88Patchy hypopigmentation of hair (HP:0011365)2.04022747
89Optic nerve hypoplasia (HP:0000609)2.03388196
90Encephalitis (HP:0002383)2.02725543
91Medial flaring of the eyebrow (HP:0010747)2.01937503
92Cerebral edema (HP:0002181)2.01702338
93Poor head control (HP:0002421)2.00723544
94Aplasia/Hypoplasia of the tibia (HP:0005772)2.00651150
95Dry hair (HP:0011359)2.00440579
96Meningitis (HP:0001287)2.00280042
97Abnormality of the labia minora (HP:0012880)2.00272511
98Abnormal pupillary function (HP:0007686)1.99689027
99Abnormal activity of mitochondrial respiratory chain (HP:0011922)1.98501630
100Decreased activity of mitochondrial respiratory chain (HP:0008972)1.98501630
101Increased serum lactate (HP:0002151)1.98009487
102Febrile seizures (HP:0002373)1.97686996
103Short tibia (HP:0005736)1.97047634
104Abnormality of alanine metabolism (HP:0010916)1.96336850
105Hyperalaninemia (HP:0003348)1.96336850
106Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.96336850
107Paralysis (HP:0003470)1.95804155
108Elevated erythrocyte sedimentation rate (HP:0003565)1.95704854
109Stomatitis (HP:0010280)1.95636902
110Renal tubular dysfunction (HP:0000124)1.95591975
111Postnatal microcephaly (HP:0005484)1.94899299
112Decreased central vision (HP:0007663)1.92838234
113Increased intramyocellular lipid droplets (HP:0012240)1.91529718
114Pancreatic cysts (HP:0001737)1.91168205
115Increased density of long bones (HP:0006392)1.91040256
116Atrophy/Degeneration involving motor neurons (HP:0007373)1.90957642
117Retinal dysplasia (HP:0007973)1.90620130
118Exercise intolerance (HP:0003546)1.88087888
119Mediastinal lymphadenopathy (HP:0100721)1.87698446
120Chromosomal breakage induced by crosslinking agents (HP:0003221)1.87573326
121Autoimmune hemolytic anemia (HP:0001890)1.86595356
122Abnormal hair whorl (HP:0010721)1.84999552
123Hyperglycinemia (HP:0002154)1.84138306
124Azoospermia (HP:0000027)1.83206433
125Abnormality of the prostate (HP:0008775)1.82469920
126Microretrognathia (HP:0000308)1.81240011
127Polyphagia (HP:0002591)1.80447666
128White forelock (HP:0002211)1.80375545
129Hepatosplenomegaly (HP:0001433)1.79274521
130Neutropenia (HP:0001875)1.77425402
131Abnormality of dental color (HP:0011073)1.77036205
132Lactic acidosis (HP:0003128)1.76471414
133Prolonged partial thromboplastin time (HP:0003645)1.75633612
134Abnormality of aromatic amino acid family metabolism (HP:0004338)1.74087862
135Abnormality of the columella (HP:0009929)1.73389295
136Myelodysplasia (HP:0002863)1.73095815
137Nephrogenic diabetes insipidus (HP:0009806)1.72903188
138Myositis (HP:0100614)1.72656439
139Recurrent bacterial skin infections (HP:0005406)1.72524831
140Median cleft lip (HP:0000161)1.71211823
141Vacuolated lymphocytes (HP:0001922)1.70024671
142Agnosia (HP:0010524)1.69746042
143Abnormality of macrophages (HP:0004311)1.69323746
144Optic neuritis (HP:0100653)1.68563488
145Retrobulbar optic neuritis (HP:0100654)1.68563488
146Abnormal auditory evoked potentials (HP:0006958)1.68189910
147Male pseudohermaphroditism (HP:0000037)1.66962642
148Abnormality of the heme biosynthetic pathway (HP:0010472)1.66365454
149Molar tooth sign on MRI (HP:0002419)1.64989935
150Abnormality of midbrain morphology (HP:0002418)1.64989935
151Hypomagnesemia (HP:0002917)1.64672949
152Reticulocytopenia (HP:0001896)1.64655729
153Concave nail (HP:0001598)1.64392514
154Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.63559882
155Agammaglobulinemia (HP:0004432)1.62967888
156Chromsome breakage (HP:0040012)1.60658938
157Acute hepatic failure (HP:0006554)1.59646530
158Lethargy (HP:0001254)1.58678038
159Lissencephaly (HP:0001339)1.57310710
160Degeneration of the lateral corticospinal tracts (HP:0002314)1.56615294
161Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)1.56615294
162X-linked dominant inheritance (HP:0001423)1.56120444
163Aplasia/hypoplasia of the uterus (HP:0008684)1.55156328

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CASK5.07402860
2TNIK4.53656549
3MUSK4.14596289
4EIF2AK14.13821959
5STK163.50244433
6TAOK32.92967204
7TRIM282.70646535
8EIF2AK32.64359966
9MKNK22.37813089
10PRPF4B2.24849707
11MAP2K72.17796082
12IRAK42.10202638
13VRK22.04344087
14MAP3K121.97081871
15NLK1.93069948
16YES11.89177599
17MKNK11.82557603
18EIF2AK21.76534565
19PIM21.71841128
20BMPR21.70319946
21ADRBK21.68067474
22MARK31.59709278
23MAP4K21.57779646
24SRPK11.52733658
25IRAK31.52267113
26ARAF1.44288853
27MAP3K141.41541121
28NME21.40366349
29TEC1.38421965
30TXK1.35453102
31PNCK1.33342347
32BMPR1B1.28926810
33BRSK21.27840420
34PLK31.22464156
35CLK11.19420456
36CDK191.17845216
37MAPK131.17561988
38MAP3K51.15870826
39GRK71.14150630
40VRK11.13616164
41CAMKK21.11609638
42RIPK41.10048240
43MST41.05765646
44STK31.02268688
45IKBKE1.00402259
46BMX0.96674034
47RAF10.96540174
48PBK0.96495555
49BLK0.95359231
50NEK10.94632397
51AKT30.94127473
52KIT0.93748134
53GRK60.91321404
54CDC70.90433003
55ZAK0.89305807
56BCKDK0.88019246
57TSSK60.83102165
58IKBKB0.82848689
59BRAF0.81750139
60PLK40.81523784
61MAPKAPK50.79114306
62STK240.79102870
63CDK30.78435591
64SIK30.78338994
65TAOK10.76354001
66ERBB30.75340177
67BTK0.75183895
68PDK20.75019206
69NEK60.73144310
70FES0.72817527
71PAK10.72503866
72IRAK10.72344434
73TLK10.72240259
74ILK0.71771340
75PLK10.71765912
76PINK10.71322738
77STK390.70129498
78SGK20.69579326
79DYRK20.68811239
80IRAK20.68744114
81TAF10.64963347
82KSR10.64903685
83MAPK150.63206360
84OXSR10.62227953
85SYK0.61586738
86TNK20.58602875
87BCR0.57242941
88PTK2B0.56711209
89PLK20.56710877
90RPS6KC10.55889609
91RPS6KL10.55889609
92STK40.54979297
93CSNK1A1L0.54043707
94LYN0.53971010
95CAMK10.53005787
96MELK0.52855411
97MYLK0.52747903
98CSF1R0.52723511
99WEE10.52691382
100HCK0.52565564
101RPS6KA60.52540987
102NTRK30.52465305
103GRK50.51548470
104CCNB10.51547254
105ADRBK10.51382408
106CAMK2B0.51244209
107NME10.51216458
108DAPK30.50810882
109WNK30.50660524
110BUB10.50372452
111SGK2230.50196350
112SGK4940.50196350
113TGFBR10.48379671
114MAP3K30.48142978
115FRK0.47432593
116NUAK10.47356997
117GRK10.47159954
118MAP3K90.46153496
119DMPK0.43751585
120MAPKAPK30.43340282
121CDK80.42686262
122TESK20.42589249
123TIE10.42435943
124MAPK40.42330298
125ATR0.42232362
126MAP2K60.39328859
127PIM10.38566855
128CSNK2A10.37279878
129CAMK2D0.37053892
130CAMK2A0.36614436
131DYRK30.36025336
132PRKCE0.35250878
133MATK0.34924732
134CSNK1G30.34345314
135UHMK10.33775782
136CSNK1G10.33032851
137CAMK2G0.32311662
138FGR0.30690235
139LCK0.30250560
140AURKA0.30165058
141TAOK20.29684487
142ACVR1B0.29299551
143EPHA40.28414779
144RPS6KB10.28042953

Predicted pathways (KEGG)

RankGene SetZ-score
1Protein export_Homo sapiens_hsa030603.10189162
2Ribosome_Homo sapiens_hsa030103.07398088
3Proteasome_Homo sapiens_hsa030503.01724012
4Oxidative phosphorylation_Homo sapiens_hsa001902.94745161
5Pathogenic Escherichia coli infection_Homo sapiens_hsa051302.41524799
6RNA polymerase_Homo sapiens_hsa030202.14200027
7Homologous recombination_Homo sapiens_hsa034402.09330920
8Parkinsons disease_Homo sapiens_hsa050122.09225568
9Cytosolic DNA-sensing pathway_Homo sapiens_hsa046232.06131844
10Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006012.02478459
11SNARE interactions in vesicular transport_Homo sapiens_hsa041301.98116090
12Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.89805299
13DNA replication_Homo sapiens_hsa030301.84451584
14Basal transcription factors_Homo sapiens_hsa030221.83794096
15Non-homologous end-joining_Homo sapiens_hsa034501.76428637
16Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.74946011
17Huntingtons disease_Homo sapiens_hsa050161.71345255
18Fatty acid elongation_Homo sapiens_hsa000621.71105514
19Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008601.68328674
20Alzheimers disease_Homo sapiens_hsa050101.64893629
21Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.64005909
22Pyrimidine metabolism_Homo sapiens_hsa002401.62535863
23Fanconi anemia pathway_Homo sapiens_hsa034601.61291571
24Phototransduction_Homo sapiens_hsa047441.58588232
25Base excision repair_Homo sapiens_hsa034101.57302720
26Platelet activation_Homo sapiens_hsa046111.56182711
27One carbon pool by folate_Homo sapiens_hsa006701.51213024
28Allograft rejection_Homo sapiens_hsa053301.48455715
29Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.47274160
30Sphingolipid metabolism_Homo sapiens_hsa006001.47067296
31Cell cycle_Homo sapiens_hsa041101.42970776
32RNA transport_Homo sapiens_hsa030131.41392100
33Arachidonic acid metabolism_Homo sapiens_hsa005901.40086616
34Graft-versus-host disease_Homo sapiens_hsa053321.39118587
35Legionellosis_Homo sapiens_hsa051341.38003419
36Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.30149309
37Purine metabolism_Homo sapiens_hsa002301.29239920
38Other glycan degradation_Homo sapiens_hsa005111.28763801
39Rheumatoid arthritis_Homo sapiens_hsa053231.27596856
40Collecting duct acid secretion_Homo sapiens_hsa049661.24865651
41Cysteine and methionine metabolism_Homo sapiens_hsa002701.17929716
42Nicotine addiction_Homo sapiens_hsa050331.16029403
43Asthma_Homo sapiens_hsa053101.15511956
44Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.14921548
45Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.14153995
46Selenocompound metabolism_Homo sapiens_hsa004501.13823380
47Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.13597927
48Ether lipid metabolism_Homo sapiens_hsa005651.12759322
49p53 signaling pathway_Homo sapiens_hsa041151.12051662
50Primary immunodeficiency_Homo sapiens_hsa053401.08533517
51Nucleotide excision repair_Homo sapiens_hsa034201.08512448
52Autoimmune thyroid disease_Homo sapiens_hsa053201.08453652
53Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050141.08020985
54N-Glycan biosynthesis_Homo sapiens_hsa005101.07614964
55Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.04834084
56Olfactory transduction_Homo sapiens_hsa047401.01844176
57Steroid hormone biosynthesis_Homo sapiens_hsa001401.01564489
58Mismatch repair_Homo sapiens_hsa034301.01267105
59Shigellosis_Homo sapiens_hsa051311.00277145
60Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.96951456
61Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.96849495
62Caffeine metabolism_Homo sapiens_hsa002320.94529471
63Intestinal immune network for IgA production_Homo sapiens_hsa046720.94213298
64Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.94109035
65Sulfur metabolism_Homo sapiens_hsa009200.94071833
66RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.90527393
67Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.89669325
68Nitrogen metabolism_Homo sapiens_hsa009100.87938699
69Hematopoietic cell lineage_Homo sapiens_hsa046400.87398732
70Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.85623171
71Taste transduction_Homo sapiens_hsa047420.84259454
72Linoleic acid metabolism_Homo sapiens_hsa005910.81206838
73Toll-like receptor signaling pathway_Homo sapiens_hsa046200.79501938
74Phagosome_Homo sapiens_hsa041450.79400527
75Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.79100037
76Serotonergic synapse_Homo sapiens_hsa047260.78358278
77RNA degradation_Homo sapiens_hsa030180.78242773
78NF-kappa B signaling pathway_Homo sapiens_hsa040640.76836534
79Measles_Homo sapiens_hsa051620.73450062
80Vibrio cholerae infection_Homo sapiens_hsa051100.72001303
81Metabolic pathways_Homo sapiens_hsa011000.69241403
82Chemokine signaling pathway_Homo sapiens_hsa040620.68986850
83Oocyte meiosis_Homo sapiens_hsa041140.65992126
84Type I diabetes mellitus_Homo sapiens_hsa049400.65603849
85Spliceosome_Homo sapiens_hsa030400.64767107
86Folate biosynthesis_Homo sapiens_hsa007900.63495205
87Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.63074297
88Steroid biosynthesis_Homo sapiens_hsa001000.62985923
89Histidine metabolism_Homo sapiens_hsa003400.62368448
90Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.61635471
91Glutathione metabolism_Homo sapiens_hsa004800.61173653
92Regulation of autophagy_Homo sapiens_hsa041400.61111541
93Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.55615322
94Malaria_Homo sapiens_hsa051440.53413441
95Propanoate metabolism_Homo sapiens_hsa006400.53137559
96Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.52354667
97Leishmaniasis_Homo sapiens_hsa051400.51594878
98Thyroid cancer_Homo sapiens_hsa052160.51069116
99T cell receptor signaling pathway_Homo sapiens_hsa046600.49397603
100Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.49204625
101Peroxisome_Homo sapiens_hsa041460.48994500
102Pentose and glucuronate interconversions_Homo sapiens_hsa000400.48745843
103Hepatitis B_Homo sapiens_hsa051610.48558785
104Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.48073684
105Viral carcinogenesis_Homo sapiens_hsa052030.47378237
106Herpes simplex infection_Homo sapiens_hsa051680.47226227
107Systemic lupus erythematosus_Homo sapiens_hsa053220.46988296
108African trypanosomiasis_Homo sapiens_hsa051430.46863321
109alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.46794996
110Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.45344132
111Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.45212285
112Apoptosis_Homo sapiens_hsa042100.44060028
113Vitamin digestion and absorption_Homo sapiens_hsa049770.43121289
114Morphine addiction_Homo sapiens_hsa050320.42079203
115Pertussis_Homo sapiens_hsa051330.41753299
116Synaptic vesicle cycle_Homo sapiens_hsa047210.40324335
117Retinol metabolism_Homo sapiens_hsa008300.39880653
118NOD-like receptor signaling pathway_Homo sapiens_hsa046210.39134532
119Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.38918591
120Jak-STAT signaling pathway_Homo sapiens_hsa046300.37723172
121Calcium signaling pathway_Homo sapiens_hsa040200.36683264
122Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.35078143
123Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.35059923
124Tuberculosis_Homo sapiens_hsa051520.34425564
125Osteoclast differentiation_Homo sapiens_hsa043800.34284126
126Alcoholism_Homo sapiens_hsa050340.33996476
127Epstein-Barr virus infection_Homo sapiens_hsa051690.33062267
128Chemical carcinogenesis_Homo sapiens_hsa052040.32654579
129Glutamatergic synapse_Homo sapiens_hsa047240.32580729
130Sulfur relay system_Homo sapiens_hsa041220.29906556
131Primary bile acid biosynthesis_Homo sapiens_hsa001200.29206072
132Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.28330064
133Drug metabolism - other enzymes_Homo sapiens_hsa009830.28168221

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