

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | eosinophil chemotaxis (GO:0048245) | 6.38289598 |
| 2 | negative regulation by host of viral transcription (GO:0043922) | 6.12911445 |
| 3 | eosinophil migration (GO:0072677) | 5.76877216 |
| 4 | regulation of T cell tolerance induction (GO:0002664) | 5.44240079 |
| 5 | regulation of regulatory T cell differentiation (GO:0045589) | 5.40581005 |
| 6 | positive regulation of tolerance induction (GO:0002645) | 5.34718794 |
| 7 | regulation of lymphocyte chemotaxis (GO:1901623) | 5.07290820 |
| 8 | pyrimidine nucleoside catabolic process (GO:0046135) | 4.99987244 |
| 9 | sequestering of actin monomers (GO:0042989) | 4.98825222 |
| 10 | positive regulation of calcium-mediated signaling (GO:0050850) | 4.93951952 |
| 11 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 4.93766635 |
| 12 | Arp2/3 complex-mediated actin nucleation (GO:0034314) | 4.93238987 |
| 13 | negative regulation of T cell apoptotic process (GO:0070233) | 4.91912876 |
| 14 | positive regulation of interleukin-8 secretion (GO:2000484) | 4.84921170 |
| 15 | positive T cell selection (GO:0043368) | 4.84363383 |
| 16 | macrophage chemotaxis (GO:0048246) | 4.82190582 |
| 17 | positive thymic T cell selection (GO:0045059) | 4.77654267 |
| 18 | negative regulation of viral genome replication (GO:0045071) | 4.50176227 |
| 19 | regulation of tolerance induction (GO:0002643) | 4.44962446 |
| 20 | actin nucleation (GO:0045010) | 4.39785311 |
| 21 | cytolysis (GO:0019835) | 4.32406222 |
| 22 | T cell migration (GO:0072678) | 4.32356535 |
| 23 | positive regulation of monocyte chemotaxis (GO:0090026) | 4.29536963 |
| 24 | regulation of activation of Janus kinase activity (GO:0010533) | 4.17889300 |
| 25 | regulation of T cell chemotaxis (GO:0010819) | 4.16710456 |
| 26 | positive regulation of T cell chemotaxis (GO:0010820) | 4.16710456 |
| 27 | regulation of chronic inflammatory response (GO:0002676) | 4.12965627 |
| 28 | positive regulation of lymphocyte migration (GO:2000403) | 3.98514647 |
| 29 | cellular response to interleukin-15 (GO:0071350) | 3.97623813 |
| 30 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 3.96760949 |
| 31 | positive regulation of gamma-delta T cell activation (GO:0046645) | 3.86399851 |
| 32 | positive regulation of T cell apoptotic process (GO:0070234) | 3.86294092 |
| 33 | positive regulation of natural killer cell mediated immunity (GO:0002717) | 3.84608532 |
| 34 | positive regulation of natural killer cell mediated cytotoxicity (GO:0045954) | 3.83776640 |
| 35 | regulation of interleukin-8 secretion (GO:2000482) | 3.69996681 |
| 36 | positive regulation of leukocyte mediated cytotoxicity (GO:0001912) | 3.68412396 |
| 37 | thymic T cell selection (GO:0045061) | 3.62902989 |
| 38 | regulation of mononuclear cell migration (GO:0071675) | 3.61915836 |
| 39 | negative T cell selection (GO:0043383) | 3.57890950 |
| 40 | regulation of calcium-mediated signaling (GO:0050848) | 3.57374080 |
| 41 | protein neddylation (GO:0045116) | 3.55971645 |
| 42 | positive regulation of B cell differentiation (GO:0045579) | 3.55024892 |
| 43 | modulation by host of viral transcription (GO:0043921) | 3.49441259 |
| 44 | modulation by host of symbiont transcription (GO:0052472) | 3.49441259 |
| 45 | positive regulation of defense response to virus by host (GO:0002230) | 3.47861387 |
| 46 | regulation of B cell receptor signaling pathway (GO:0050855) | 3.42356710 |
| 47 | T cell costimulation (GO:0031295) | 3.38581432 |
| 48 | modulation of transcription in other organism involved in symbiotic interaction (GO:0052312) | 3.37573599 |
| 49 | negative regulation of viral transcription (GO:0032897) | 3.37164522 |
| 50 | regulation of T cell apoptotic process (GO:0070232) | 3.36232670 |
| 51 | lymphocyte costimulation (GO:0031294) | 3.34401683 |
| 52 | positive regulation of T cell mediated cytotoxicity (GO:0001916) | 3.33627624 |
| 53 | negative regulation of lymphocyte apoptotic process (GO:0070229) | 3.32861573 |
| 54 | DNA demethylation (GO:0080111) | 3.32483206 |
| 55 | positive regulation of lamellipodium assembly (GO:0010592) | 3.32402571 |
| 56 | regulation of B cell differentiation (GO:0045577) | 3.32039553 |
| 57 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 3.29728655 |
| 58 | regulation of natural killer cell mediated cytotoxicity (GO:0042269) | 3.29446369 |
| 59 | regulation of natural killer cell mediated immunity (GO:0002715) | 3.29446369 |
| 60 | response to interleukin-15 (GO:0070672) | 3.28754756 |
| 61 | T cell selection (GO:0045058) | 3.28528267 |
| 62 | regulation of T cell receptor signaling pathway (GO:0050856) | 3.28363514 |
| 63 | positive regulation of cell killing (GO:0031343) | 3.25481682 |
| 64 | lymphocyte chemotaxis (GO:0048247) | 3.24825754 |
| 65 | regulation of macrophage chemotaxis (GO:0010758) | 3.23282751 |
| 66 | positive regulation of interleukin-4 production (GO:0032753) | 3.20914642 |
| 67 | regulation of gamma-delta T cell differentiation (GO:0045586) | 3.19019838 |
| 68 | T cell receptor signaling pathway (GO:0050852) | 3.18399174 |
| 69 | monocyte chemotaxis (GO:0002548) | 3.18320880 |
| 70 | antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590) | 3.16091346 |
| 71 | regulation of leukocyte mediated cytotoxicity (GO:0001910) | 3.15896003 |
| 72 | regulation of chemokine-mediated signaling pathway (GO:0070099) | 3.15485752 |
| 73 | regulation of interleukin-2 biosynthetic process (GO:0045076) | 3.15309411 |
| 74 | regulation of viral genome replication (GO:0045069) | 3.14504814 |
| 75 | pyrimidine-containing compound catabolic process (GO:0072529) | 3.14208774 |
| 76 | negative regulation of antigen receptor-mediated signaling pathway (GO:0050858) | 3.12533847 |
| 77 | regulation of antigen receptor-mediated signaling pathway (GO:0050854) | 3.09478458 |
| 78 | positive regulation of lymphocyte apoptotic process (GO:0070230) | 3.08806727 |
| 79 | positive regulation of interleukin-2 biosynthetic process (GO:0045086) | 3.07937975 |
| 80 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.06003336 |
| 81 | respiratory burst (GO:0045730) | 3.05908093 |
| 82 | negative regulation of calcium ion transport into cytosol (GO:0010523) | 3.03132936 |
| 83 | negative regulation of viral process (GO:0048525) | 3.00052213 |
| 84 | regulation of lymphocyte migration (GO:2000401) | 2.97203691 |
| 85 | positive regulation of translational initiation (GO:0045948) | 2.92781530 |
| 86 | natural killer cell activation (GO:0030101) | 2.88693701 |
| 87 | cellular defense response (GO:0006968) | 2.86797667 |
| 88 | positive regulation of T cell migration (GO:2000406) | 2.85895101 |
| 89 | regulation of cell killing (GO:0031341) | 2.85746223 |
| 90 | negative thymic T cell selection (GO:0045060) | 2.85057921 |
| 91 | DNA dealkylation (GO:0035510) | 2.84900872 |
| 92 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 2.84134387 |
| 93 | regulation of T cell mediated cytotoxicity (GO:0001914) | 2.83315872 |
| 94 | regulation of interleukin-12 biosynthetic process (GO:0045075) | 2.80005350 |
| 95 | cytidine metabolic process (GO:0046087) | 11.9208491 |
| 96 | cytidine catabolic process (GO:0006216) | 11.9208491 |
| 97 | cytidine deamination (GO:0009972) | 11.9208491 |
| 98 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 10.9187644 |
| 99 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 10.4412505 |
| 100 | DNA deamination (GO:0045006) | 10.2947781 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 4.04940304 |
| 2 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 3.69625944 |
| 3 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 3.40105897 |
| 4 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 3.36874536 |
| 5 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 3.12845434 |
| 6 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 3.07136458 |
| 7 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 3.03098967 |
| 8 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.92504733 |
| 9 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 2.60196626 |
| 10 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 2.56700445 |
| 11 | MYB_26560356_Chip-Seq_TH2_Human | 2.52668390 |
| 12 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 2.48709253 |
| 13 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 2.31921421 |
| 14 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 2.21708811 |
| 15 | VDR_22108803_ChIP-Seq_LS180_Human | 2.14093790 |
| 16 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 2.12351987 |
| 17 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 2.01016801 |
| 18 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 11.7573016 |
| 19 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 1.98008261 |
| 20 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.91370450 |
| 21 | RUNX_20019798_ChIP-Seq_JUKART_Human | 1.87708925 |
| 22 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 1.78405582 |
| 23 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.77390413 |
| 24 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 1.74300796 |
| 25 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.63460312 |
| 26 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 1.62927696 |
| 27 | GATA3_26560356_Chip-Seq_TH2_Human | 1.58664409 |
| 28 | MYB_26560356_Chip-Seq_TH1_Human | 1.56847322 |
| 29 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.56682546 |
| 30 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.54895292 |
| 31 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.52924567 |
| 32 | HTT_18923047_ChIP-ChIP_STHdh_Human | 1.44538202 |
| 33 | UTX_26944678_Chip-Seq_JUKART_Human | 1.44038948 |
| 34 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.40002436 |
| 35 | MAF_26560356_Chip-Seq_TH2_Human | 1.36405617 |
| 36 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.31605731 |
| 37 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 1.30949219 |
| 38 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 1.29900297 |
| 39 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.29251249 |
| 40 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.23482240 |
| 41 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.23111271 |
| 42 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.22981190 |
| 43 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.21785684 |
| 44 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 1.21440964 |
| 45 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 1.20741404 |
| 46 | MAF_26560356_Chip-Seq_TH1_Human | 1.18129559 |
| 47 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 1.16414032 |
| 48 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.15436873 |
| 49 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.09478474 |
| 50 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.08145158 |
| 51 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.08053044 |
| 52 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 1.07996185 |
| 53 | BCL6_27268052_Chip-Seq_Bcells_Human | 1.06072827 |
| 54 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.04868147 |
| 55 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 1.04689865 |
| 56 | TAF2_19829295_ChIP-Seq_ESCs_Human | 1.03622984 |
| 57 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.03226854 |
| 58 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.01544917 |
| 59 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.00940964 |
| 60 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 0.99976205 |
| 61 | SPI1_23547873_ChIP-Seq_NB4_Human | 0.99816073 |
| 62 | NANOG_20526341_ChIP-Seq_ESCs_Human | 0.99394526 |
| 63 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 0.98617326 |
| 64 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 0.95706892 |
| 65 | AR_20517297_ChIP-Seq_VCAP_Human | 0.94837959 |
| 66 | TP53_22573176_ChIP-Seq_HFKS_Human | 0.93904486 |
| 67 | BMI1_19503595_ChIP-Seq_MEFsC_Mouse | 0.93642178 |
| 68 | CTCF_20526341_ChIP-Seq_ESCs_Human | 0.92041782 |
| 69 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 0.91633380 |
| 70 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 0.91633380 |
| 71 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 0.91305406 |
| 72 | GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.91058680 |
| 73 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 0.90519307 |
| 74 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 0.90369803 |
| 75 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 0.88431401 |
| 76 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 0.88273415 |
| 77 | GATA6_21074721_ChIP-Seq_CACO-2_Mouse | 0.86429450 |
| 78 | P300_27268052_Chip-Seq_Bcells_Human | 0.85306850 |
| 79 | GATA3_26560356_Chip-Seq_TH1_Human | 0.85043863 |
| 80 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 0.84801257 |
| 81 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 0.84375300 |
| 82 | YY1_22570637_ChIP-Seq_MALME-3M_Human | 0.84273266 |
| 83 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 0.83097273 |
| 84 | RUNX1_17652178_ChIP-ChIP_JURKAT_Human | 0.82574429 |
| 85 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.82313090 |
| 86 | ER_23166858_ChIP-Seq_MCF-7_Human | 0.82207253 |
| 87 | ERG_20517297_ChIP-Seq_VCAP_Human | 0.81426904 |
| 88 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 0.80045822 |
| 89 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 0.79175641 |
| 90 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 0.78414261 |
| 91 | NANOG_19829295_ChIP-Seq_ESCs_Human | 0.78082132 |
| 92 | SOX2_19829295_ChIP-Seq_ESCs_Human | 0.78082132 |
| 93 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 0.77413717 |
| 94 | GATA6_21074721_ChIP-Seq_CACO-2_Human | 0.76289944 |
| 95 | NCOR_22424771_ChIP-Seq_293T_Human | 0.75365986 |
| 96 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 0.75332798 |
| 97 | FOXH1_21741376_ChIP-Seq_ESCs_Human | 0.74563357 |
| 98 | RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.74300063 |
| 99 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 0.74069955 |
| 100 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 0.74060823 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0005671_abnormal_response_to | 6.93460646 |
| 2 | MP0009785_altered_susceptibility_to | 3.90115052 |
| 3 | MP0006082_CNS_inflammation | 3.71192541 |
| 4 | MP0009333_abnormal_splenocyte_physiolog | 3.37686213 |
| 5 | MP0001835_abnormal_antigen_presentation | 2.96465113 |
| 6 | MP0001873_stomach_inflammation | 2.94423967 |
| 7 | MP0005000_abnormal_immune_tolerance | 2.93929894 |
| 8 | MP0003763_abnormal_thymus_physiology | 2.91610693 |
| 9 | MP0002148_abnormal_hypersensitivity_rea | 2.62415716 |
| 10 | MP0003866_abnormal_defecation | 2.51962047 |
| 11 | MP0001800_abnormal_humoral_immune | 2.51192124 |
| 12 | MP0002420_abnormal_adaptive_immunity | 2.49252346 |
| 13 | MP0005025_abnormal_response_to | 2.48920354 |
| 14 | MP0002723_abnormal_immune_serum | 2.46902952 |
| 15 | MP0001819_abnormal_immune_cell | 2.37394206 |
| 16 | MP0002166_altered_tumor_susceptibility | 2.33579641 |
| 17 | MP0005387_immune_system_phenotype | 2.32516743 |
| 18 | MP0001790_abnormal_immune_system | 2.32516743 |
| 19 | MP0002102_abnormal_ear_morphology | 2.08445696 |
| 20 | MP0002405_respiratory_system_inflammati | 1.99592418 |
| 21 | MP0010155_abnormal_intestine_physiology | 1.91899744 |
| 22 | MP0002452_abnormal_antigen_presenting | 1.91892039 |
| 23 | MP0000716_abnormal_immune_system | 1.87514093 |
| 24 | MP0003448_altered_tumor_morphology | 1.79564019 |
| 25 | MP0002876_abnormal_thyroid_physiology | 1.74312664 |
| 26 | MP0001845_abnormal_inflammatory_respons | 1.73111342 |
| 27 | MP0002398_abnormal_bone_marrow | 1.72813644 |
| 28 | MP0002006_tumorigenesis | 1.69693746 |
| 29 | MP0000685_abnormal_immune_system | 1.62857729 |
| 30 | MP0002933_joint_inflammation | 1.51510668 |
| 31 | MP0002419_abnormal_innate_immunity | 1.50618087 |
| 32 | MP0002722_abnormal_immune_system | 1.49776799 |
| 33 | MP0000703_abnormal_thymus_morphology | 1.49694414 |
| 34 | MP0004947_skin_inflammation | 1.43618932 |
| 35 | MP0001905_abnormal_dopamine_level | 1.43431449 |
| 36 | MP0000372_irregular_coat_pigmentation | 1.40381242 |
| 37 | MP0001853_heart_inflammation | 1.38817306 |
| 38 | MP0001919_abnormal_reproductive_system | 1.36147524 |
| 39 | MP0002429_abnormal_blood_cell | 1.35337436 |
| 40 | MP0003786_premature_aging | 1.34749308 |
| 41 | MP0000689_abnormal_spleen_morphology | 1.33769038 |
| 42 | MP0002877_abnormal_melanocyte_morpholog | 1.32684037 |
| 43 | MP0008469_abnormal_protein_level | 1.29001473 |
| 44 | MP0008995_early_reproductive_senescence | 1.28875336 |
| 45 | MP0005310_abnormal_salivary_gland | 1.24637407 |
| 46 | MP0005464_abnormal_platelet_physiology | 1.24554186 |
| 47 | MP0001984_abnormal_olfaction | 1.19384259 |
| 48 | MP0005377_hearing/vestibular/ear_phenot | 1.17175754 |
| 49 | MP0003878_abnormal_ear_physiology | 1.17175754 |
| 50 | MP0008872_abnormal_physiological_respon | 1.17051273 |
| 51 | MP0005645_abnormal_hypothalamus_physiol | 1.15031200 |
| 52 | MP0002277_abnormal_respiratory_mucosa | 1.14924289 |
| 53 | MP0003436_decreased_susceptibility_to | 1.13727927 |
| 54 | MP0003137_abnormal_impulse_conducting | 1.11616212 |
| 55 | MP0001485_abnormal_pinna_reflex | 1.09519620 |
| 56 | MP0009763_increased_sensitivity_to | 1.09299271 |
| 57 | MP0001661_extended_life_span | 1.09013956 |
| 58 | MP0002163_abnormal_gland_morphology | 1.04915900 |
| 59 | MP0002132_abnormal_respiratory_system | 1.04161654 |
| 60 | MP0001188_hyperpigmentation | 1.00054454 |
| 61 | MP0006072_abnormal_retinal_apoptosis | 0.99730306 |
| 62 | MP0004742_abnormal_vestibular_system | 0.97182465 |
| 63 | MP0001727_abnormal_embryo_implantation | 0.97097892 |
| 64 | MP0000858_altered_metastatic_potential | 0.95250596 |
| 65 | MP0002693_abnormal_pancreas_physiology | 0.94960002 |
| 66 | MP0005389_reproductive_system_phenotype | 0.85782789 |
| 67 | MP0009764_decreased_sensitivity_to | 0.84668632 |
| 68 | MP0005257_abnormal_intraocular_pressure | 0.83192054 |
| 69 | MP0004134_abnormal_chest_morphology | 0.82366886 |
| 70 | MP0006035_abnormal_mitochondrial_morpho | 0.81995665 |
| 71 | MP0003724_increased_susceptibility_to | 0.81842467 |
| 72 | MP0009697_abnormal_copulation | 0.78387036 |
| 73 | MP0002837_dystrophic_cardiac_calcinosis | 0.74184671 |
| 74 | MP0003787_abnormal_imprinting | 0.73783153 |
| 75 | MP0009745_abnormal_behavioral_response | 0.72013496 |
| 76 | MP0005253_abnormal_eye_physiology | 0.70376738 |
| 77 | MP0008873_increased_physiological_sensi | 0.69705918 |
| 78 | MP0003045_fibrosis | 0.69336566 |
| 79 | MP0008875_abnormal_xenobiotic_pharmacok | 0.69224597 |
| 80 | MP0002019_abnormal_tumor_incidence | 0.68861886 |
| 81 | MP0008877_abnormal_DNA_methylation | 0.68295916 |
| 82 | MP0010386_abnormal_urinary_bladder | 0.68061151 |
| 83 | MP0001529_abnormal_vocalization | 0.67668975 |
| 84 | MP0003195_calcinosis | 0.66305084 |
| 85 | MP0006036_abnormal_mitochondrial_physio | 0.65706986 |
| 86 | MP0004145_abnormal_muscle_electrophysio | 0.64592473 |
| 87 | MP0002733_abnormal_thermal_nociception | 0.64158829 |
| 88 | MP0008789_abnormal_olfactory_epithelium | 0.62780534 |
| 89 | MP0005166_decreased_susceptibility_to | 0.62227437 |
| 90 | MP0003075_altered_response_to | 0.61836048 |
| 91 | MP0002234_abnormal_pharynx_morphology | 0.61309684 |
| 92 | MP0001765_abnormal_ion_homeostasis | 0.59619970 |
| 93 | MP0005636_abnormal_mineral_homeostasis | 0.59304735 |
| 94 | MP0005551_abnormal_eye_electrophysiolog | 0.58875197 |
| 95 | MP0004142_abnormal_muscle_tone | 0.58697818 |
| 96 | MP0005379_endocrine/exocrine_gland_phen | 0.58011662 |
| 97 | MP0009379_abnormal_foot_pigmentation | 0.57661356 |
| 98 | MP0009765_abnormal_xenobiotic_induced | 0.57446700 |
| 99 | MP0001440_abnormal_grooming_behavior | 0.56500724 |
| 100 | MP0001968_abnormal_touch/_nociception | 0.55215175 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Abnormality of T cell number (HP:0011839) | 6.28407437 |
| 2 | T lymphocytopenia (HP:0005403) | 6.17972531 |
| 3 | Aplastic anemia (HP:0001915) | 5.71102953 |
| 4 | Autoimmune hemolytic anemia (HP:0001890) | 5.49438755 |
| 5 | Hypoproteinemia (HP:0003075) | 4.55138756 |
| 6 | Increased IgM level (HP:0003496) | 4.31146029 |
| 7 | Severe combined immunodeficiency (HP:0004430) | 4.28076148 |
| 8 | Elevated erythrocyte sedimentation rate (HP:0003565) | 4.10217233 |
| 9 | Abnormality of T cells (HP:0002843) | 4.08917465 |
| 10 | IgG deficiency (HP:0004315) | 4.02709143 |
| 11 | Chronic diarrhea (HP:0002028) | 3.93557372 |
| 12 | Abnormality of eosinophils (HP:0001879) | 3.86019832 |
| 13 | Abnormality of B cell number (HP:0010975) | 3.78008723 |
| 14 | Abnormality of macrophages (HP:0004311) | 3.71951899 |
| 15 | Thyroiditis (HP:0100646) | 3.68402323 |
| 16 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 3.63030385 |
| 17 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 3.63030385 |
| 18 | Eosinophilia (HP:0001880) | 3.53287015 |
| 19 | Combined immunodeficiency (HP:0005387) | 3.46479799 |
| 20 | Recurrent bacterial skin infections (HP:0005406) | 3.40638769 |
| 21 | Autoimmune thrombocytopenia (HP:0001973) | 3.39307485 |
| 22 | Mitochondrial inheritance (HP:0001427) | 3.36834448 |
| 23 | Increased intramyocellular lipid droplets (HP:0012240) | 3.23897194 |
| 24 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 3.23881662 |
| 25 | Recurrent abscess formation (HP:0002722) | 3.20989331 |
| 26 | Abnormality of the prostate (HP:0008775) | 3.14152288 |
| 27 | 3-Methylglutaconic aciduria (HP:0003535) | 2.99481145 |
| 28 | Renal Fanconi syndrome (HP:0001994) | 2.98462689 |
| 29 | Obstructive lung disease (HP:0006536) | 2.96848045 |
| 30 | Chronic obstructive pulmonary disease (HP:0006510) | 2.96848045 |
| 31 | Abnormality of cells of the lymphoid lineage (HP:0012140) | 2.96059672 |
| 32 | Lymphopenia (HP:0001888) | 2.92892540 |
| 33 | Congenital stationary night blindness (HP:0007642) | 2.92597210 |
| 34 | Hepatocellular necrosis (HP:0001404) | 2.92036063 |
| 35 | Leukocytosis (HP:0001974) | 2.89707881 |
| 36 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.88102336 |
| 37 | Meningitis (HP:0001287) | 2.83150340 |
| 38 | Recurrent gram-negative bacterial infections (HP:0005420) | 2.81421145 |
| 39 | Acute necrotizing encephalopathy (HP:0006965) | 2.75755500 |
| 40 | Recurrent viral infections (HP:0004429) | 2.74851401 |
| 41 | Granulocytopenia (HP:0001913) | 2.72351775 |
| 42 | Encephalitis (HP:0002383) | 2.71886605 |
| 43 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.71305271 |
| 44 | B lymphocytopenia (HP:0010976) | 2.68457817 |
| 45 | Amyotrophic lateral sclerosis (HP:0007354) | 2.66850929 |
| 46 | Increased hepatocellular lipid droplets (HP:0006565) | 2.65272716 |
| 47 | Recurrent fungal infections (HP:0002841) | 2.61746401 |
| 48 | Increased muscle lipid content (HP:0009058) | 2.60581898 |
| 49 | Abnormal mitochondria in muscle tissue (HP:0008316) | 2.59595222 |
| 50 | Hypoalbuminemia (HP:0003073) | 2.57382466 |
| 51 | Abnormal albumin level (HP:0012116) | 2.57382466 |
| 52 | Increased CSF lactate (HP:0002490) | 2.50757945 |
| 53 | Recurrent bronchitis (HP:0002837) | 2.43683259 |
| 54 | Recurrent skin infections (HP:0001581) | 2.39067194 |
| 55 | Recurrent cutaneous fungal infections (HP:0011370) | 2.38884833 |
| 56 | Chronic mucocutaneous candidiasis (HP:0002728) | 2.38884833 |
| 57 | Pancreatic cysts (HP:0001737) | 2.38742870 |
| 58 | Hepatic necrosis (HP:0002605) | 2.35153558 |
| 59 | Mediastinal lymphadenopathy (HP:0100721) | 2.34042623 |
| 60 | Progressive macrocephaly (HP:0004481) | 2.33196517 |
| 61 | Retrobulbar optic neuritis (HP:0100654) | 2.29060096 |
| 62 | Optic neuritis (HP:0100653) | 2.29060096 |
| 63 | Gangrene (HP:0100758) | 2.27480050 |
| 64 | Eczematoid dermatitis (HP:0000976) | 2.26192237 |
| 65 | Abnormality of T cell physiology (HP:0011840) | 2.25603923 |
| 66 | Pulmonary infiltrates (HP:0002113) | 2.25142211 |
| 67 | Lipid accumulation in hepatocytes (HP:0006561) | 2.21852854 |
| 68 | Hypergammaglobulinemia (HP:0010702) | 2.21418002 |
| 69 | Hemiplegia (HP:0002301) | 2.21105804 |
| 70 | Abnormality of midbrain morphology (HP:0002418) | 2.20993672 |
| 71 | Molar tooth sign on MRI (HP:0002419) | 2.20993672 |
| 72 | Recurrent otitis media (HP:0000403) | 2.20912308 |
| 73 | Stomatitis (HP:0010280) | 2.19432317 |
| 74 | Pustule (HP:0200039) | 2.19049751 |
| 75 | Hemoptysis (HP:0002105) | 2.17841607 |
| 76 | IgM deficiency (HP:0002850) | 2.17815653 |
| 77 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.17621657 |
| 78 | Cerebral edema (HP:0002181) | 2.12537859 |
| 79 | Stomach cancer (HP:0012126) | 2.09957548 |
| 80 | Joint swelling (HP:0001386) | 2.08398512 |
| 81 | Lymphoma (HP:0002665) | 2.06068728 |
| 82 | Myositis (HP:0100614) | 2.05982526 |
| 83 | Optic disc pallor (HP:0000543) | 2.00656274 |
| 84 | Acute encephalopathy (HP:0006846) | 2.00029405 |
| 85 | Agammaglobulinemia (HP:0004432) | 1.99197301 |
| 86 | Vasculitis (HP:0002633) | 1.98220622 |
| 87 | Aplasia/hypoplasia of the uterus (HP:0008684) | 1.98196200 |
| 88 | Ureteral stenosis (HP:0000071) | 1.97912745 |
| 89 | Hypoplasia of the thymus (HP:0000778) | 1.94207769 |
| 90 | Bronchitis (HP:0012387) | 1.93359143 |
| 91 | Abnormal rod and cone electroretinograms (HP:0008323) | 1.92744135 |
| 92 | Decreased central vision (HP:0007663) | 1.89818915 |
| 93 | Abnormality of renal resorption (HP:0011038) | 1.89258553 |
| 94 | Abnormality of the alveolar ridges (HP:0006477) | 1.88696062 |
| 95 | Exertional dyspnea (HP:0002875) | 1.87506690 |
| 96 | Ureteral obstruction (HP:0006000) | 1.87026765 |
| 97 | Hypoplasia of the uterus (HP:0000013) | 1.83853040 |
| 98 | Pancytopenia (HP:0001876) | 1.83502575 |
| 99 | True hermaphroditism (HP:0010459) | 1.82126918 |
| 100 | Pulmonary embolism (HP:0002204) | 1.81071167 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | KDR | 6.46864235 |
| 2 | TXK | 6.18609969 |
| 3 | TESK2 | 4.30868742 |
| 4 | ZAK | 3.49450866 |
| 5 | BCKDK | 3.32302977 |
| 6 | MAP4K1 | 2.67573398 |
| 7 | ITK | 2.39772944 |
| 8 | TLK1 | 2.27519069 |
| 9 | TESK1 | 2.17788634 |
| 10 | ADRBK2 | 2.07795578 |
| 11 | VRK2 | 1.78683669 |
| 12 | GRK7 | 1.78655947 |
| 13 | MAP3K11 | 1.77152419 |
| 14 | LIMK1 | 1.69860425 |
| 15 | VRK1 | 1.68800591 |
| 16 | PRKCQ | 1.68426904 |
| 17 | FRK | 1.66061354 |
| 18 | WNK4 | 1.61507718 |
| 19 | MAP3K12 | 1.60928039 |
| 20 | FES | 1.59187773 |
| 21 | MAP4K2 | 1.53702812 |
| 22 | MAPKAPK3 | 1.51847521 |
| 23 | CSK | 1.49177348 |
| 24 | TAOK3 | 1.48381395 |
| 25 | PINK1 | 1.47839795 |
| 26 | BUB1 | 1.46455787 |
| 27 | SYK | 1.43332935 |
| 28 | LCK | 1.34167151 |
| 29 | GRK1 | 1.26995304 |
| 30 | GRK6 | 1.26682772 |
| 31 | MST4 | 1.25141491 |
| 32 | TEC | 1.19336401 |
| 33 | PIK3CA | 1.15508816 |
| 34 | NUAK1 | 1.09865959 |
| 35 | TIE1 | 0.93196326 |
| 36 | MAP2K6 | 0.87099329 |
| 37 | MYLK | 0.85403709 |
| 38 | LYN | 0.83018736 |
| 39 | CAMKK2 | 0.80794037 |
| 40 | TRPM7 | 0.78101964 |
| 41 | TNK2 | 0.77644642 |
| 42 | ZAP70 | 0.76818376 |
| 43 | ERBB3 | 0.69276973 |
| 44 | SCYL2 | 0.68616419 |
| 45 | IKBKB | 0.67979445 |
| 46 | EIF2AK3 | 0.66600850 |
| 47 | JAK2 | 0.64757785 |
| 48 | BTK | 0.62895469 |
| 49 | FYN | 0.61762778 |
| 50 | PDK2 | 0.61364159 |
| 51 | DAPK1 | 0.59153810 |
| 52 | CSNK1G3 | 0.59017883 |
| 53 | ROCK1 | 0.58676997 |
| 54 | INSRR | 0.56584089 |
| 55 | IKBKE | 0.55689286 |
| 56 | PIM1 | 0.55385123 |
| 57 | INSR | 0.53673809 |
| 58 | CSF1R | 0.53478801 |
| 59 | IGF1R | 0.50519463 |
| 60 | CAMKK1 | 0.49748967 |
| 61 | JAK3 | 0.49271054 |
| 62 | WNK3 | 0.49188510 |
| 63 | BCR | 0.48052531 |
| 64 | PRKCA | 0.44039732 |
| 65 | RPS6KA4 | 0.43620774 |
| 66 | AURKA | 0.43388040 |
| 67 | OBSCN | 0.43147927 |
| 68 | TRIM28 | 0.41440869 |
| 69 | PIK3CG | 0.40106767 |
| 70 | PRKCH | 0.40050319 |
| 71 | PIM2 | 0.39696777 |
| 72 | MAP2K7 | 0.37990072 |
| 73 | TBK1 | 0.37910475 |
| 74 | CAMK2A | 0.37498673 |
| 75 | MATK | 0.36563334 |
| 76 | MAP3K5 | 0.35758780 |
| 77 | RPS6KA5 | 0.35500025 |
| 78 | PRKACA | 0.34106083 |
| 79 | PAK1 | 0.31660874 |
| 80 | CSNK1A1L | 0.31221637 |
| 81 | KIT | 0.31005806 |
| 82 | MUSK | 0.30869203 |
| 83 | FGFR1 | 0.29966027 |
| 84 | AKT3 | 0.29910587 |
| 85 | MAPK13 | 0.29090958 |
| 86 | CSNK1G1 | 0.28312587 |
| 87 | ADRBK1 | 0.28252455 |
| 88 | ABL2 | 0.27991518 |
| 89 | NME1 | 0.27719691 |
| 90 | OXSR1 | 0.27228997 |
| 91 | SRPK1 | 0.24902634 |
| 92 | ACVR1B | 0.24419985 |
| 93 | PRKCE | 0.24320728 |
| 94 | CSNK1G2 | 0.24141663 |
| 95 | CSNK2A1 | 0.23960401 |
| 96 | TYRO3 | 0.22299780 |
| 97 | PLK2 | 0.21131809 |
| 98 | BLK | 0.20714521 |
| 99 | ABL1 | 0.20437091 |
| 100 | IRAK4 | 0.20406674 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Primary immunodeficiency_Homo sapiens_hsa05340 | 6.10752617 |
| 2 | Proteasome_Homo sapiens_hsa03050 | 4.59839399 |
| 3 | Graft-versus-host disease_Homo sapiens_hsa05332 | 3.54205771 |
| 4 | Antigen processing and presentation_Homo sapiens_hsa04612 | 3.51954374 |
| 5 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 3.05371577 |
| 6 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.02181684 |
| 7 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 2.86653602 |
| 8 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 2.83361532 |
| 9 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 2.73842557 |
| 10 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 2.72986475 |
| 11 | Parkinsons disease_Homo sapiens_hsa05012 | 2.70211635 |
| 12 | Allograft rejection_Homo sapiens_hsa05330 | 2.69001326 |
| 13 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 2.37603830 |
| 14 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 2.15478719 |
| 15 | RNA polymerase_Homo sapiens_hsa03020 | 1.99653530 |
| 16 | Salmonella infection_Homo sapiens_hsa05132 | 1.89130675 |
| 17 | Alzheimers disease_Homo sapiens_hsa05010 | 1.82678254 |
| 18 | Protein export_Homo sapiens_hsa03060 | 1.78430959 |
| 19 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.69550356 |
| 20 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 1.58328030 |
| 21 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 1.57598625 |
| 22 | Huntingtons disease_Homo sapiens_hsa05016 | 1.45859045 |
| 23 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.41795995 |
| 24 | Measles_Homo sapiens_hsa05162 | 1.40808563 |
| 25 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 1.36234710 |
| 26 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 1.29166925 |
| 27 | Viral myocarditis_Homo sapiens_hsa05416 | 1.25635323 |
| 28 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 1.18687820 |
| 29 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 1.14582774 |
| 30 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.12552423 |
| 31 | Shigellosis_Homo sapiens_hsa05131 | 1.01846597 |
| 32 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.01170250 |
| 33 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.91972841 |
| 34 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.91507227 |
| 35 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.85144902 |
| 36 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.80371903 |
| 37 | Asthma_Homo sapiens_hsa05310 | 0.79652830 |
| 38 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 0.79146305 |
| 39 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.78824800 |
| 40 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.77422763 |
| 41 | Malaria_Homo sapiens_hsa05144 | 0.77279341 |
| 42 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.74376479 |
| 43 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.73248722 |
| 44 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.72671933 |
| 45 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.71049429 |
| 46 | Phototransduction_Homo sapiens_hsa04744 | 0.70631206 |
| 47 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.62524101 |
| 48 | Peroxisome_Homo sapiens_hsa04146 | 0.56487780 |
| 49 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.54907869 |
| 50 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.54748106 |
| 51 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.52536038 |
| 52 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.50602768 |
| 53 | Homologous recombination_Homo sapiens_hsa03440 | 0.49810515 |
| 54 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.48577395 |
| 55 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.46129327 |
| 56 | Ribosome_Homo sapiens_hsa03010 | 0.46103577 |
| 57 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.45170165 |
| 58 | Apoptosis_Homo sapiens_hsa04210 | 0.44967240 |
| 59 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.44669164 |
| 60 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.43723741 |
| 61 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.43368751 |
| 62 | Pertussis_Homo sapiens_hsa05133 | 0.42380722 |
| 63 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.41305200 |
| 64 | Osteoclast differentiation_Homo sapiens_hsa04380 | 0.40674692 |
| 65 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.39614223 |
| 66 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.39434026 |
| 67 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.38874013 |
| 68 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.37961478 |
| 69 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.37059851 |
| 70 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.35427587 |
| 71 | Prion diseases_Homo sapiens_hsa05020 | 0.35036886 |
| 72 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.33782905 |
| 73 | Leishmaniasis_Homo sapiens_hsa05140 | 0.33260752 |
| 74 | Phagosome_Homo sapiens_hsa04145 | 0.32871792 |
| 75 | Purine metabolism_Homo sapiens_hsa00230 | 0.32703535 |
| 76 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.31208455 |
| 77 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.31021587 |
| 78 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.30574220 |
| 79 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.30568724 |
| 80 | RNA degradation_Homo sapiens_hsa03018 | 0.30182794 |
| 81 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.30059412 |
| 82 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.26855208 |
| 83 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.25360736 |
| 84 | HTLV-I infection_Homo sapiens_hsa05166 | 0.24905301 |
| 85 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.24732858 |
| 86 | Olfactory transduction_Homo sapiens_hsa04740 | 0.24685234 |
| 87 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.22975045 |
| 88 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.21459003 |
| 89 | Legionellosis_Homo sapiens_hsa05134 | 0.18796581 |
| 90 | Endocytosis_Homo sapiens_hsa04144 | 0.17097546 |
| 91 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.16332586 |
| 92 | Metabolic pathways_Homo sapiens_hsa01100 | 0.16304680 |
| 93 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.16272785 |
| 94 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.12862902 |
| 95 | Nicotine addiction_Homo sapiens_hsa05033 | 0.12275393 |
| 96 | Retinol metabolism_Homo sapiens_hsa00830 | 0.12196120 |
| 97 | Tuberculosis_Homo sapiens_hsa05152 | 0.11246538 |
| 98 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.11110364 |
| 99 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.10394794 |
| 100 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.09971342 |

