Rank | Gene Set | Z-score |
---|---|---|
1 | * pigment biosynthetic process (GO:0046148) | 7.23679240 |
2 | regulation of endothelial cell chemotaxis (GO:2001026) | 6.02259283 |
3 | * pigment metabolic process (GO:0042440) | 5.57120478 |
4 | myotube differentiation (GO:0014902) | 5.53159745 |
5 | mesenchymal-epithelial cell signaling (GO:0060638) | 5.39048451 |
6 | endosome to melanosome transport (GO:0035646) | 5.34863176 |
7 | endosome to pigment granule transport (GO:0043485) | 5.34863176 |
8 | * melanocyte differentiation (GO:0030318) | 5.33440075 |
9 | negative regulation of hydrogen peroxide-induced cell death (GO:1903206) | 5.25805868 |
10 | pigmentation (GO:0043473) | 5.18808031 |
11 | positive regulation of neuroblast proliferation (GO:0002052) | 5.09000744 |
12 | * pigment cell differentiation (GO:0050931) | 4.84474695 |
13 | negative regulation of response to reactive oxygen species (GO:1901032) | 4.77305247 |
14 | calcium-mediated signaling using intracellular calcium source (GO:0035584) | 4.75070735 |
15 | pigment granule transport (GO:0051904) | 4.74861727 |
16 | aromatic amino acid family metabolic process (GO:0009072) | 4.74610902 |
17 | melanosome transport (GO:0032402) | 4.72555194 |
18 | regulation of hydrogen peroxide-induced cell death (GO:1903205) | 4.71294974 |
19 | establishment of pigment granule localization (GO:0051905) | 4.53014466 |
20 | establishment of melanosome localization (GO:0032401) | 4.49819718 |
21 | pigment granule localization (GO:0051875) | 4.44825384 |
22 | regulation of branching involved in salivary gland morphogenesis (GO:0060693) | 4.42373142 |
23 | melanosome localization (GO:0032400) | 4.41555653 |
24 | endothelial cell morphogenesis (GO:0001886) | 4.18778847 |
25 | * melanosome organization (GO:0032438) | 4.00330051 |
26 | * melanin biosynthetic process (GO:0042438) | 33.6385552 |
27 | * melanin metabolic process (GO:0006582) | 30.2483781 |
28 | nerve growth factor signaling pathway (GO:0038180) | 3.98945234 |
29 | regulation of integrin-mediated signaling pathway (GO:2001044) | 3.88814707 |
30 | * phenol-containing compound metabolic process (GO:0018958) | 3.80888614 |
31 | * pigment granule organization (GO:0048753) | 3.78997469 |
32 | somatic stem cell division (GO:0048103) | 3.76233963 |
33 | semaphorin-plexin signaling pathway (GO:0071526) | 3.73447297 |
34 | proline transport (GO:0015824) | 3.72449443 |
35 | vitamin A metabolic process (GO:0006776) | 3.66914261 |
36 | regulation of neuroblast proliferation (GO:1902692) | 3.57417085 |
37 | regulation of superoxide anion generation (GO:0032928) | 3.50016108 |
38 | mitotic G1 DNA damage checkpoint (GO:0031571) | 3.27403814 |
39 | negative regulation of DNA damage response, signal transduction by p53 class mediator (GO:0043518) | 3.25478046 |
40 | antigen processing and presentation via MHC class Ib (GO:0002475) | 3.25330210 |
41 | * neuroepithelial cell differentiation (GO:0060563) | 3.25142496 |
42 | positive regulation of receptor recycling (GO:0001921) | 3.21538262 |
43 | regulation of epithelial cell proliferation involved in prostate gland development (GO:0060768) | 3.20371078 |
44 | regulation of somitogenesis (GO:0014807) | 3.19899498 |
45 | muscle cell migration (GO:0014812) | 3.13847015 |
46 | regulation of protein sumoylation (GO:0033233) | 3.12346806 |
47 | G-protein coupled glutamate receptor signaling pathway (GO:0007216) | 3.10769695 |
48 | ventricular cardiac muscle cell development (GO:0055015) | 3.10304052 |
49 | negative regulation of tumor necrosis factor-mediated signaling pathway (GO:0010804) | 3.10016359 |
50 | negative regulation of interleukin-1 beta production (GO:0032691) | 3.10004076 |
51 | enteric nervous system development (GO:0048484) | 3.07596574 |
52 | barbed-end actin filament capping (GO:0051016) | 3.01839921 |
53 | * secondary metabolite biosynthetic process (GO:0044550) | 27.4695234 |
54 | regulation of antigen processing and presentation of peptide antigen (GO:0002583) | 2.95598663 |
55 | retinal rod cell development (GO:0046548) | 2.89023727 |
56 | positive regulation of DNA-dependent DNA replication (GO:2000105) | 2.88742521 |
57 | diterpenoid biosynthetic process (GO:0016102) | 2.87206007 |
58 | response to epinephrine (GO:0071871) | 2.85564380 |
59 | mitotic G1/S transition checkpoint (GO:0044819) | 2.82953591 |
60 | fibroblast migration (GO:0010761) | 2.80828485 |
61 | G1 DNA damage checkpoint (GO:0044783) | 2.78849676 |
62 | righting reflex (GO:0060013) | 2.75271013 |
63 | cell migration involved in heart development (GO:0060973) | 2.72164237 |
64 | dosage compensation (GO:0007549) | 2.71741003 |
65 | negative regulation of organelle assembly (GO:1902116) | 2.70417138 |
66 | response to iron ion (GO:0010039) | 2.69221534 |
67 | regulation of response to reactive oxygen species (GO:1901031) | 2.68757944 |
68 | cellular response to reactive nitrogen species (GO:1902170) | 2.62455166 |
69 | bone remodeling (GO:0046849) | 2.62337892 |
70 | response to magnesium ion (GO:0032026) | 2.59570950 |
71 | stress fiber assembly (GO:0043149) | 2.58294351 |
72 | positive regulation of neural precursor cell proliferation (GO:2000179) | 2.57263952 |
73 | mesenchymal to epithelial transition involved in metanephros morphogenesis (GO:0003337) | 2.56654230 |
74 | negative regulation of oxidative stress-induced cell death (GO:1903202) | 2.54509688 |
75 | cellular response to nitric oxide (GO:0071732) | 2.53394649 |
76 | negative regulation of JUN kinase activity (GO:0043508) | 2.53016497 |
77 | behavioral response to ethanol (GO:0048149) | 2.52675606 |
78 | Rap protein signal transduction (GO:0032486) | 2.51936074 |
79 | regulation of superoxide metabolic process (GO:0090322) | 2.50570725 |
80 | hair cell differentiation (GO:0035315) | 2.49993237 |
81 | polyol catabolic process (GO:0046174) | 2.49484169 |
82 | cellular response to thyroid hormone stimulus (GO:0097067) | 2.46460960 |
83 | negative regulation of response to oxidative stress (GO:1902883) | 2.44424662 |
84 | negative regulation of cellular response to oxidative stress (GO:1900408) | 2.44424662 |
85 | negative regulation of interleukin-1 production (GO:0032692) | 2.42690624 |
86 | peripheral nervous system development (GO:0007422) | 2.42431176 |
87 | negative regulation of fatty acid biosynthetic process (GO:0045717) | 2.42162645 |
88 | stem cell division (GO:0017145) | 2.40685093 |
89 | signal peptide processing (GO:0006465) | 2.40050869 |
90 | cellular response to oxygen radical (GO:0071450) | 2.37484479 |
91 | removal of superoxide radicals (GO:0019430) | 2.37484479 |
92 | cellular response to superoxide (GO:0071451) | 2.37484479 |
93 | pinocytosis (GO:0006907) | 2.37285790 |
94 | Rac protein signal transduction (GO:0016601) | 2.36857409 |
95 | regulation of sister chromatid cohesion (GO:0007063) | 2.36375872 |
96 | platelet dense granule organization (GO:0060155) | 2.35916917 |
97 | mitotic G2 DNA damage checkpoint (GO:0007095) | 2.34116432 |
98 | cellular response to nerve growth factor stimulus (GO:1990090) | 2.33129353 |
99 | response to nerve growth factor (GO:1990089) | 2.33129353 |
100 | auditory receptor cell stereocilium organization (GO:0060088) | 2.31275906 |
101 | regulation of DNA endoreduplication (GO:0032875) | 2.30680991 |
102 | negative regulation of cell cycle arrest (GO:0071157) | 2.30578611 |
103 | negative regulation of chemokine production (GO:0032682) | 2.30107994 |
104 | regulation of cellular respiration (GO:0043457) | 2.28687219 |
105 | establishment of nucleus localization (GO:0040023) | 2.23984164 |
106 | response to thyroid hormone (GO:0097066) | 2.23216531 |
107 | autophagic vacuole fusion (GO:0000046) | 2.22101847 |
108 | vesicle localization (GO:0051648) | 2.20609218 |
109 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 2.18859935 |
110 | regulation of centriole replication (GO:0046599) | 2.18367822 |
111 | negative regulation of TOR signaling (GO:0032007) | 2.17362249 |
112 | response to nitric oxide (GO:0071731) | 2.15922376 |
113 | alanine transport (GO:0032328) | 2.15742882 |
114 | regulation of clathrin-mediated endocytosis (GO:2000369) | 2.15468249 |
115 | piRNA metabolic process (GO:0034587) | 2.15207703 |
116 | 4-hydroxyproline metabolic process (GO:0019471) | 2.14977240 |
117 | regulation of lipoprotein metabolic process (GO:0050746) | 2.14710313 |
118 | intracellular pH reduction (GO:0051452) | 2.14021752 |
119 | terpenoid biosynthetic process (GO:0016114) | 2.10342091 |
120 | positive regulation of inositol phosphate biosynthetic process (GO:0060732) | 2.09769661 |
121 | osteoclast differentiation (GO:0030316) | 2.09023430 |
122 | mitotic sister chromatid segregation (GO:0000070) | 2.07536839 |
123 | * organic hydroxy compound biosynthetic process (GO:1901617) | 2.02753787 |
124 | positive regulation of glucose transport (GO:0010828) | 2.02709012 |
125 | tyrosine metabolic process (GO:0006570) | 15.4107738 |
126 | developmental pigmentation (GO:0048066) | 13.1548495 |
127 | * phenol-containing compound biosynthetic process (GO:0046189) | 10.4292678 |
128 | * secondary metabolic process (GO:0019748) | 10.1922321 |
129 | negative regulation of fatty acid metabolic process (GO:0045922) | 1.98240736 |
130 | myelin assembly (GO:0032288) | 1.93287061 |
131 | regulation of apoptotic cell clearance (GO:2000425) | 1.92841434 |
132 | regulation of early endosome to late endosome transport (GO:2000641) | 1.90621972 |
133 | peptidyl-lysine dimethylation (GO:0018027) | 1.87012199 |
134 | cellular glucuronidation (GO:0052695) | 1.86888130 |
135 | positive chemotaxis (GO:0050918) | 1.85886799 |
136 | positive regulation of osteoblast proliferation (GO:0033690) | 1.85785901 |
137 | * columnar/cuboidal epithelial cell differentiation (GO:0002065) | 1.84077573 |
138 | regulation of short-term neuronal synaptic plasticity (GO:0048172) | 1.79927221 |
139 | regulation of oxidative stress-induced cell death (GO:1903201) | 1.79544476 |
140 | establishment of mitotic spindle orientation (GO:0000132) | 1.77928466 |
141 | centrosome duplication (GO:0051298) | 1.76126727 |
142 | negative regulation of histone methylation (GO:0031061) | 1.74949740 |
143 | negative regulation of membrane potential (GO:0045837) | 1.73935604 |
144 | glycoprotein catabolic process (GO:0006516) | 1.73640498 |
145 | folic acid-containing compound biosynthetic process (GO:0009396) | 1.71932624 |
146 | positive regulation of Rap GTPase activity (GO:0032854) | 1.71267409 |
147 | protein K6-linked ubiquitination (GO:0085020) | 1.70135664 |
148 | glucuronate metabolic process (GO:0019585) | 1.67571097 |
149 | uronic acid metabolic process (GO:0006063) | 1.67571097 |
150 | organelle membrane fusion (GO:0090174) | 1.65655844 |
151 | glycolytic process (GO:0006096) | 1.65268944 |
152 | regulation of cellular response to oxidative stress (GO:1900407) | 1.63829646 |
153 | specification of organ identity (GO:0010092) | 1.61497009 |
154 | phosphorylated carbohydrate dephosphorylation (GO:0046838) | 1.60216085 |
155 | inositol phosphate dephosphorylation (GO:0046855) | 1.60216085 |
156 | angiogenesis involved in wound healing (GO:0060055) | 1.59566403 |
157 | inositol phosphate catabolic process (GO:0071545) | 1.58529238 |
158 | regulation of histone H3-K9 methylation (GO:0051570) | 1.57869878 |
159 | chondroitin sulfate biosynthetic process (GO:0030206) | 1.56838336 |
160 | establishment of mitotic spindle localization (GO:0040001) | 1.53894666 |
161 | centrosome localization (GO:0051642) | 1.53322444 |
162 | spinal cord association neuron differentiation (GO:0021527) | 1.52526971 |
163 | thymus development (GO:0048538) | 1.51842146 |
164 | glycogen biosynthetic process (GO:0005978) | 1.51422320 |
Rank | Gene Set | Z-score |
---|---|---|
1 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 8.85837147 |
2 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 7.38280908 |
3 | GATA1_22025678_ChIP-Seq_K562_Human | 4.51871361 |
4 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 4.27414444 |
5 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 3.93029761 |
6 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 3.81745880 |
7 | E2F7_22180533_ChIP-Seq_HELA_Human | 3.49468297 |
8 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 3.35826256 |
9 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 3.31286461 |
10 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 3.30647435 |
11 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 2.87259705 |
12 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 2.84701908 |
13 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 2.77058446 |
14 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 2.76286128 |
15 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 2.76119299 |
16 | HIF1A_21447827_ChIP-Seq_MCF-7_Human | 2.56801393 |
17 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 2.36608388 |
18 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.25036103 |
19 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.23183641 |
20 | EGR1_19032775_ChIP-ChIP_M12_Human | 2.15105421 |
21 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 2.02751096 |
22 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 10.3110953 |
23 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.89415139 |
24 | TFEB_21752829_ChIP-Seq_HELA_Human | 1.87989334 |
25 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 1.85507332 |
26 | * MITF_21258399_ChIP-Seq_MELANOMA_Human | 1.79552477 |
27 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.79408959 |
28 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 1.78071332 |
29 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.74526144 |
30 | ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 1.70695699 |
31 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 1.64784356 |
32 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.60678090 |
33 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.57066260 |
34 | CLOCK_20551151_ChIP-Seq_293T_Human | 1.52835382 |
35 | ESR1_17901129_ChIP-ChIP_LIVER_Mouse | 1.50333533 |
36 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.47339836 |
37 | * PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.41956761 |
38 | ZNF263_19887448_ChIP-Seq_K562_Human | 1.41210242 |
39 | FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human | 1.40647169 |
40 | * AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.39220640 |
41 | FUS_26573619_Chip-Seq_HEK293_Human | 1.37823469 |
42 | * RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse | 1.36616746 |
43 | DMRT1_23473982_ChIP-Seq_TESTES_Mouse | 1.36560232 |
44 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 1.35402034 |
45 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 1.32240083 |
46 | KAP1_22055183_ChIP-Seq_ESCs_Mouse | 1.32103213 |
47 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.30832027 |
48 | P300_19829295_ChIP-Seq_ESCs_Human | 1.28558871 |
49 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 1.27141889 |
50 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 1.26653958 |
51 | WT1_19549856_ChIP-ChIP_CCG9911_Human | 1.26638854 |
52 | CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse | 1.25125467 |
53 | ESR1_22446102_ChIP-Seq_UTERUS_Mouse | 1.24673156 |
54 | TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.23384126 |
55 | RUNX2_24764292_ChIP-Seq_MC3T3_Mouse | 1.21994433 |
56 | FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human | 1.21314018 |
57 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 1.20615969 |
58 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.19434710 |
59 | BRD4_25478319_ChIP-Seq_HGPS_Human | 1.19309069 |
60 | SMAD2_18955504_ChIP-ChIP_HaCaT_Human | 1.17916268 |
61 | SMAD3_18955504_ChIP-ChIP_HaCaT_Human | 1.17916268 |
62 | AR_21909140_ChIP-Seq_LNCAP_Human | 1.17643701 |
63 | TP53_18474530_ChIP-ChIP_U2OS_Human | 1.16586783 |
64 | KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 1.16032456 |
65 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 1.15982911 |
66 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.15097323 |
67 | CTNNB1_20460455_ChIP-Seq_HCT116_Human | 1.14919758 |
68 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.14411712 |
69 | * TAL1_26923725_Chip-Seq_HPCs_Mouse | 1.14291619 |
70 | FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.13608285 |
71 | TBX20_22080862_ChIP-Seq_HEART_Mouse | 1.12999298 |
72 | TBX20_22328084_ChIP-Seq_HEART_Mouse | 1.12999298 |
73 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.12790072 |
74 | E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 1.12299267 |
75 | PPAR_26484153_Chip-Seq_NCI-H1993_Human | 1.11786738 |
76 | FOXO1_23066095_ChIP-Seq_LIVER_Mouse | 1.11581089 |
77 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.10682498 |
78 | GATA3_20176728_ChIP-ChIP_TSCs_Mouse | 1.10573221 |
79 | RUNX1_17652178_ChIP-ChIP_JURKAT_Human | 1.08113930 |
80 | CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse | 1.06663179 |
81 | TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse | 1.06432544 |
82 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 1.05996416 |
83 | SMAD1_18555785_Chip-Seq_ESCs_Mouse | 1.03894804 |
84 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.03303997 |
85 | P300_27058665_Chip-Seq_ZR-75-30cells_Human | 1.02582438 |
86 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.02323438 |
87 | FOXA1_26743006_Chip-Seq_LNCaP-abl_Human | 1.01942818 |
88 | EOMES_20176728_ChIP-ChIP_TSCs_Mouse | 1.01617564 |
89 | SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse | 1.00806108 |
90 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 1.00628894 |
91 | ESRRB_18555785_ChIP-Seq_MESCs_Mouse | 1.00372675 |
92 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 1.00284651 |
93 | GATA1_26923725_Chip-Seq_HPCs_Mouse | 0.99979333 |
94 | SOX17_20123909_ChIP-Seq_XEN_Mouse | 0.99878896 |
95 | HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse | 0.99871678 |
96 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 0.98935098 |
97 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 0.97821711 |
98 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 0.95814031 |
99 | UBF1/2_26484160_Chip-Seq_HMECs_Human | 0.95234534 |
100 | ETS1_22383799_ChIP-Seq_G1ME_Mouse | 0.95001869 |
101 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 0.94956758 |
102 | JUN_21703547_ChIP-Seq_K562_Human | 0.94349544 |
103 | SOX2_18555785_Chip-Seq_ESCs_Mouse | 0.92309909 |
104 | TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 0.91700939 |
105 | NACC1_18358816_ChIP-ChIP_MESCs_Mouse | 0.91626773 |
106 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 0.91228716 |
107 | PRDM5_23873026_ChIP-Seq_MEFs_Mouse | 0.91056475 |
108 | OCT4_21477851_ChIP-Seq_ESCs_Mouse | 0.90944357 |
109 | ELK1_19687146_ChIP-ChIP_HELA_Human | 0.90333094 |
110 | * SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 0.89981641 |
111 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 0.89382303 |
112 | CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.89376316 |
113 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 0.89289711 |
114 | SOX2_22085726_ChIP-Seq_NPCs_Mouse | 0.89288500 |
115 | * SMAD3_21741376_ChIP-Seq_EPCs_Human | 0.89179080 |
116 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 0.88692417 |
117 | STAT3_18555785_Chip-Seq_ESCs_Mouse | 0.88474954 |
118 | * CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse | 0.88028502 |
119 | ZNF217_24962896_ChIP-Seq_MCF-7_Human | 0.87921606 |
120 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 0.87790545 |
121 | P53_22387025_ChIP-Seq_ESCs_Mouse | 0.87267099 |
122 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 0.86802391 |
123 | ISL1_27105846_Chip-Seq_CPCs_Mouse | 0.86236395 |
124 | ESRRB_18555785_Chip-Seq_ESCs_Mouse | 0.86121508 |
125 | NFE2L2_20460467_ChIP-Seq_MEFs_Mouse | 0.85981868 |
126 | NRF2_20460467_ChIP-Seq_MEFs_Mouse | 0.85981868 |
127 | FOXO3_23340844_ChIP-Seq_DLD1_Human | 0.85571522 |
128 | GATA3_24758297_ChIP-Seq_MCF-7_Human | 0.85278689 |
129 | BCAT_22108803_ChIP-Seq_LS180_Human | 0.84966823 |
130 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 0.84456376 |
131 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 0.84257757 |
132 | TP53_16413492_ChIP-PET_HCT116_Human | 0.84108136 |
133 | DCP1A_22483619_ChIP-Seq_HELA_Human | 0.83816214 |
134 | EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse | 0.83712519 |
135 | SMAD4_19686287_ChIP-ChIP_HaCaT_Human | 0.83651503 |
136 | ATF3_27146783_Chip-Seq_COLON_Human | 0.82687432 |
137 | * CJUN_26792858_Chip-Seq_BT549_Human | 0.82441382 |
138 | TCF7L2_21901280_ChIP-Seq_H4IIE_Rat | 0.82439136 |
139 | * TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 0.82387362 |
140 | PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse | 0.82157960 |
141 | TCF4_23295773_ChIP-Seq_U87_Human | 0.82148617 |
142 | FOXA2_19822575_ChIP-Seq_HepG2_Human | 0.82098958 |
143 | SOX9_24532713_ChIP-Seq_HFSC_Mouse | 0.81592571 |
144 | NMYC_18555785_Chip-Seq_ESCs_Mouse | 0.81346419 |
145 | SMAD4_21799915_ChIP-Seq_A2780_Human | 0.80727757 |
146 | GATA4_21415370_ChIP-Seq_HL-1_Mouse | 0.80664803 |
147 | AR_21915096_ChIP-Seq_LNCaP-1F5_Human | 0.80378193 |
148 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 0.80249006 |
149 | HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse | 0.79967155 |
150 | KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human | 0.79887111 |
151 | ZFX_18555785_Chip-Seq_ESCs_Mouse | 0.79705338 |
152 | PU1_27457419_Chip-Seq_LIVER_Mouse | 0.79277885 |
153 | STAT3_23295773_ChIP-Seq_U87_Human | 0.78729817 |
154 | GF1B_26923725_Chip-Seq_HPCs_Mouse | 0.78698146 |
155 | RXR_22158963_ChIP-Seq_LIVER_Mouse | 0.77596400 |
156 | NKX2-5_21415370_ChIP-Seq_HL-1_Mouse | 0.77502554 |
157 | PPARG_20176806_ChIP-Seq_3T3-L1_Mouse | 0.76389207 |
158 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 0.76163823 |
159 | PPARA_22158963_ChIP-Seq_LIVER_Mouse | 0.75493731 |
160 | KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human | 0.75452545 |
161 | PU_27001747_Chip-Seq_BMDM_Mouse | 0.74729805 |
162 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 0.70759867 |
163 | BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 0.70110033 |
164 | * OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 0.69451938 |
165 | RUNX1_27514584_Chip-Seq_MCF-7_Human | 0.69057886 |
166 | NFIB_24661679_ChIP-Seq_LUNG_Mouse | 0.68434727 |
167 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 0.68406738 |
168 | SOX9_26525672_Chip-Seq_Limbbuds_Mouse | 0.67723265 |
169 | NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human | 0.67267901 |
170 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 0.66871798 |
171 | * AR_25329375_ChIP-Seq_VCAP_Human | 0.66788650 |
172 | LXR_22158963_ChIP-Seq_LIVER_Mouse | 0.66008598 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0005171_absent_coat_pigmentation | 9.65020342 |
2 | MP0005408_hypopigmentation | 6.00812569 |
3 | MP0003136_yellow_coat_color | 5.60998187 |
4 | MP0004381_abnormal_hair_follicle | 4.31336470 |
5 | MP0005257_abnormal_intraocular_pressure | 4.25808576 |
6 | * MP0000371_diluted_coat_color | 3.91469209 |
7 | MP0002095_abnormal_skin_pigmentation | 3.50438996 |
8 | MP0002877_abnormal_melanocyte_morpholog | 3.40232251 |
9 | MP0000015_abnormal_ear_pigmentation | 3.38312692 |
10 | MP0005075_abnormal_melanosome_morpholog | 2.64073397 |
11 | * MP0001324_abnormal_eye_pigmentation | 2.39742812 |
12 | * MP0002075_abnormal_coat/hair_pigmentati | 2.28643667 |
13 | MP0005174_abnormal_tail_pigmentation | 2.20023635 |
14 | MP0000569_abnormal_digit_pigmentation | 2.19936371 |
15 | MP0000372_irregular_coat_pigmentation | 11.7032911 |
16 | * MP0001186_pigmentation_phenotype | 1.82675394 |
17 | MP0002938_white_spotting | 1.81213586 |
18 | MP0005248_abnormal_Harderian_gland | 1.74562871 |
19 | MP0003806_abnormal_nucleotide_metabolis | 1.42326098 |
20 | MP0002638_abnormal_pupillary_reflex | 1.33174812 |
21 | MP0002090_abnormal_vision | 1.26186149 |
22 | MP0003705_abnormal_hypodermis_morpholog | 1.21528227 |
23 | MP0005409_darkened_coat_color | 1.12444053 |
24 | MP0003646_muscle_fatigue | 1.12251470 |
25 | MP0003011_delayed_dark_adaptation | 1.08679250 |
26 | * MP0005197_abnormal_uvea_morphology | 0.91953149 |
27 | MP0010234_abnormal_vibrissa_follicle | 0.83780920 |
28 | MP0005253_abnormal_eye_physiology | 0.81959275 |
29 | MP0010094_abnormal_chromosome_stability | 0.79143912 |
30 | MP0000733_abnormal_muscle_development | 0.71208879 |
31 | MP0003453_abnormal_keratinocyte_physiol | 0.70891701 |
32 | MP0001293_anophthalmia | 0.69755192 |
33 | MP0002089_abnormal_postnatal_growth/wei | 0.65794894 |
34 | MP0005058_abnormal_lysosome_morphology | 0.62453260 |
35 | * MP0000367_abnormal_coat/_hair | 0.56115855 |
36 | MP0006054_spinal_hemorrhage | 0.53600665 |
37 | MP0000377_abnormal_hair_follicle | 0.50845913 |
38 | MP0002822_catalepsy | 0.50789463 |
39 | MP0000762_abnormal_tongue_morphology | 0.50320605 |
40 | MP0009697_abnormal_copulation | 0.50173098 |
41 | MP0001485_abnormal_pinna_reflex | 0.49829588 |
42 | MP0010030_abnormal_orbit_morphology | 0.48902832 |
43 | MP0005391_vision/eye_phenotype | 0.47456189 |
44 | MP0002092_abnormal_eye_morphology | 0.47269121 |
45 | MP0010307_abnormal_tumor_latency | 0.45558100 |
46 | MP0006138_congestive_heart_failure | 0.44808814 |
47 | MP0005551_abnormal_eye_electrophysiolog | 0.44753832 |
48 | MP0005023_abnormal_wound_healing | 0.43879224 |
49 | MP0009840_abnormal_foam_cell | 0.43717138 |
50 | MP0002177_abnormal_outer_ear | 0.42241926 |
51 | MP0003566_abnormal_cell_adhesion | 0.41296307 |
52 | MP0008260_abnormal_autophagy | 0.41192945 |
53 | MP0003943_abnormal_hepatobiliary_system | 0.38114137 |
54 | MP0005623_abnormal_meninges_morphology | 0.37842839 |
55 | MP0003186_abnormal_redox_activity | 0.36974960 |
56 | MP0000465_gastrointestinal_hemorrhage | 0.34817541 |
57 | MP0008438_abnormal_cutaneous_collagen | 0.34205227 |
58 | MP0000647_abnormal_sebaceous_gland | 0.34042533 |
59 | MP0003191_abnormal_cellular_cholesterol | 0.30408150 |
60 | MP0001849_ear_inflammation | 0.29953440 |
61 | MP0003091_abnormal_cell_migration | 0.29936852 |
62 | MP0008057_abnormal_DNA_replication | 0.29932853 |
63 | MP0003950_abnormal_plasma_membrane | 0.28879439 |
64 | MP0008770_decreased_survivor_rate | 0.28829508 |
65 | MP0004084_abnormal_cardiac_muscle | 0.28508321 |
66 | MP0000749_muscle_degeneration | 0.28310774 |
67 | MP0002837_dystrophic_cardiac_calcinosis | 0.27460169 |
68 | MP0003077_abnormal_cell_cycle | 0.27408129 |
69 | MP0001958_emphysema | 0.26721765 |
70 | MP0001984_abnormal_olfaction | 0.26022901 |
71 | MP0000358_abnormal_cell_content/ | 0.25741504 |
72 | MP0004233_abnormal_muscle_weight | 0.25019459 |
73 | * MP0005193_abnormal_anterior_eye | 0.24242765 |
74 | MP0001915_intracranial_hemorrhage | 0.23303516 |
75 | MP0002396_abnormal_hematopoietic_system | 0.22330131 |
76 | MP0009046_muscle_twitch | 0.21507000 |
77 | MP0001851_eye_inflammation | 0.20501743 |
78 | MP0003567_abnormal_fetal_cardiomyocyte | 0.20101270 |
79 | MP0005451_abnormal_body_composition | 0.19866852 |
80 | MP0003172_abnormal_lysosome_physiology | 0.19341354 |
81 | MP0010352_gastrointestinal_tract_polyps | 0.19196971 |
82 | MP0004197_abnormal_fetal_growth/weight/ | 0.17572426 |
83 | MP0001188_hyperpigmentation | 0.16139983 |
84 | MP0003111_abnormal_nucleus_morphology | 0.15960217 |
85 | MP0004484_altered_response_of | 0.15200023 |
86 | MP0002139_abnormal_hepatobiliary_system | 0.14734376 |
87 | MP0002697_abnormal_eye_size | 0.13582264 |
88 | MP0008932_abnormal_embryonic_tissue | 0.12396332 |
89 | MP0004808_abnormal_hematopoietic_stem | 0.12258560 |
90 | MP0003385_abnormal_body_wall | 0.11731040 |
91 | MP0001299_abnormal_eye_distance/ | 0.11598147 |
92 | MP0004272_abnormal_basement_membrane | 0.10068915 |
93 | MP0005164_abnormal_response_to | 0.10065050 |
94 | MP0006036_abnormal_mitochondrial_physio | 0.10058955 |
95 | MP0005384_cellular_phenotype | 0.09962325 |
96 | MP0000955_abnormal_spinal_cord | 0.07991858 |
97 | MP0003632_abnormal_nervous_system | 0.07703280 |
98 | MP0002229_neurodegeneration | 0.07430123 |
99 | MP0004147_increased_porphyrin_level | 0.07355692 |
100 | MP0005621_abnormal_cell_physiology | 0.07131387 |
101 | MP0008569_lethality_at_weaning | 0.06795401 |
102 | MP0005195_abnormal_posterior_eye | 0.06527285 |
103 | MP0004134_abnormal_chest_morphology | 0.06216856 |
104 | MP0000920_abnormal_myelination | 0.06031785 |
105 | MP0009703_decreased_birth_body | 0.05974033 |
106 | MP0003938_abnormal_ear_development | 0.05834777 |
107 | MP0000747_muscle_weakness | 0.05520025 |
108 | MP0003755_abnormal_palate_morphology | 0.05293711 |
109 | MP0010678_abnormal_skin_adnexa | 0.05214256 |
110 | MP0000432_abnormal_head_morphology | 0.05063659 |
111 | MP0003937_abnormal_limbs/digits/tail_de | 0.04998743 |
112 | MP0008007_abnormal_cellular_replicative | 0.04758795 |
113 | MP0002269_muscular_atrophy | 0.04385019 |
114 | MP0003045_fibrosis | 0.04271489 |
115 | MP0000427_abnormal_hair_cycle | 0.03870529 |
116 | MP0004036_abnormal_muscle_relaxation | 0.03683305 |
117 | MP0003137_abnormal_impulse_conducting | 0.03195312 |
118 | MP0008058_abnormal_DNA_repair | 0.03013886 |
119 | MP0009384_cardiac_valve_regurgitation | 0.02959978 |
120 | MP0005330_cardiomyopathy | 0.02875566 |
121 | MP0003718_maternal_effect | 0.02828020 |
122 | MP0003634_abnormal_glial_cell | 0.02680159 |
123 | MP0010329_abnormal_lipoprotein_level | 0.02558587 |
124 | MP0002751_abnormal_autonomic_nervous | 0.02558021 |
125 | MP0005187_abnormal_penis_morphology | 0.01854238 |
126 | MP0003300_gastrointestinal_ulcer | 0.01736151 |
127 | MP0005275_abnormal_skin_tensile | 0.01722483 |
128 | MP0002060_abnormal_skin_morphology | 0.01719532 |
129 | MP0004087_abnormal_muscle_fiber | 0.01266826 |
130 | MP0005165_increased_susceptibility_to | 0.01158409 |
131 | MP0003329_amyloid_beta_deposits | 0.00742442 |
132 | MP0000537_abnormal_urethra_morphology | 0.00585687 |
133 | MP0005083_abnormal_biliary_tract | 0.00130371 |
134 | MP0000681_abnormal_thyroid_gland | 0.00068039 |
135 | MP0002128_abnormal_blood_circulation | 0.00045949 |
136 | MP0002752_abnormal_somatic_nervous | -0.0011925 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Hypopigmentation of the fundus (HP:0007894) | 8.32917501 |
2 | * Ocular albinism (HP:0001107) | 7.71041188 |
3 | Generalized hypopigmentation (HP:0007513) | 7.13366574 |
4 | * Iris hypopigmentation (HP:0007730) | 6.71970951 |
5 | White forelock (HP:0002211) | 6.53003549 |
6 | Subacute progressive viral hepatitis (HP:0006572) | 6.37051820 |
7 | Congenital sensorineural hearing impairment (HP:0008527) | 6.18642939 |
8 | Patchy hypopigmentation of hair (HP:0011365) | 5.83567531 |
9 | Hypoplasia of the iris (HP:0007676) | 5.16001893 |
10 | Cutaneous melanoma (HP:0012056) | 4.74408908 |
11 | Heterochromia iridis (HP:0001100) | 4.64268010 |
12 | Generalized hypopigmentation of hair (HP:0011358) | 4.46750665 |
13 | Bilateral sensorineural hearing impairment (HP:0008619) | 4.09028339 |
14 | Aplasia/Hypoplasia affecting the fundus (HP:0008057) | 3.91216003 |
15 | Premature graying of hair (HP:0002216) | 3.75447388 |
16 | Viral hepatitis (HP:0006562) | 3.63115966 |
17 | Micronodular cirrhosis (HP:0001413) | 3.51601030 |
18 | Albinism (HP:0001022) | 3.36203249 |
19 | Hepatocellular carcinoma (HP:0001402) | 2.98308463 |
20 | * Freckling (HP:0001480) | 2.95754966 |
21 | Neoplasm of the adrenal cortex (HP:0100641) | 2.88993078 |
22 | Congenital stationary night blindness (HP:0007642) | 2.69340511 |
23 | Amblyopia (HP:0000646) | 2.67172741 |
24 | Melanoma (HP:0002861) | 2.48042422 |
25 | Horizontal nystagmus (HP:0000666) | 2.46863209 |
26 | Asymmetric septal hypertrophy (HP:0001670) | 2.34815241 |
27 | Abnormality of vision evoked potentials (HP:0000649) | 2.24431373 |
28 | Abnormal auditory evoked potentials (HP:0006958) | 2.23340838 |
29 | Abnormality of glycolipid metabolism (HP:0010969) | 2.03312517 |
30 | Abnormality of liposaccharide metabolism (HP:0010968) | 2.03312517 |
31 | Abnormality of glycosphingolipid metabolism (HP:0004343) | 2.03312517 |
32 | Aplasia/Hypoplasia of the macula (HP:0008059) | 12.7868036 |
33 | Aplasia/Hypoplasia affecting the retina (HP:0008061) | 11.9790033 |
34 | Hypoplasia of the fovea (HP:0007750) | 11.7930497 |
35 | Aplasia/Hypoplasia of the fovea (HP:0008060) | 11.7930497 |
36 | Blue irides (HP:0000635) | 11.7020752 |
37 | Abnormality of the fovea (HP:0000493) | 10.1297643 |
38 | Urinary glycosaminoglycan excretion (HP:0003541) | 1.99869135 |
39 | Mucopolysacchariduria (HP:0008155) | 1.99869135 |
40 | Scapular winging (HP:0003691) | 1.93910187 |
41 | Abnormal gallbladder physiology (HP:0012438) | 1.93775758 |
42 | Cholecystitis (HP:0001082) | 1.93775758 |
43 | Neoplasm of the adrenal gland (HP:0100631) | 1.90176580 |
44 | Abnormality of the anterior horn cell (HP:0006802) | 1.86894393 |
45 | Degeneration of anterior horn cells (HP:0002398) | 1.86894393 |
46 | Choroideremia (HP:0001139) | 1.85748480 |
47 | Renal cell carcinoma (HP:0005584) | 1.84596181 |
48 | Vertebral compression fractures (HP:0002953) | 1.84069254 |
49 | Epidermoid cyst (HP:0200040) | 1.82253389 |
50 | Spastic diplegia (HP:0001264) | 1.82203043 |
51 | Peripheral hypomyelination (HP:0007182) | 1.81615970 |
52 | Frequent falls (HP:0002359) | 1.81006633 |
53 | Rhabdomyosarcoma (HP:0002859) | 1.79680592 |
54 | Abnormality of mucopolysaccharide metabolism (HP:0011020) | 1.79355194 |
55 | Abnormality of polysaccharide metabolism (HP:0011012) | 1.79355194 |
56 | Abnormality of glycosaminoglycan metabolism (HP:0004371) | 1.79355194 |
57 | Synophrys (HP:0000664) | 1.73782152 |
58 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 1.71072946 |
59 | Astigmatism (HP:0000483) | 1.68124235 |
60 | Underdeveloped nasal alae (HP:0000430) | 1.65145120 |
61 | Melanocytic nevus (HP:0000995) | 1.62725689 |
62 | Tongue fasciculations (HP:0001308) | 1.62607758 |
63 | Hypermelanotic macule (HP:0001034) | 1.61810911 |
64 | Dysostosis multiplex (HP:0000943) | 1.60168484 |
65 | Hepatitis (HP:0012115) | 1.56179461 |
66 | Cerebral hypomyelination (HP:0006808) | 1.47665456 |
67 | Exercise-induced muscle cramps (HP:0003710) | 1.45856312 |
68 | Hypokinesia (HP:0002375) | 1.44043470 |
69 | Facial cleft (HP:0002006) | 1.42079952 |
70 | Tented upper lip vermilion (HP:0010804) | 1.41730373 |
71 | Adrenal hypoplasia (HP:0000835) | 1.41400739 |
72 | Alacrima (HP:0000522) | 1.40252729 |
73 | Intestinal atresia (HP:0011100) | 1.40162419 |
74 | Conjunctival hamartoma (HP:0100780) | 1.38437473 |
75 | Abnormal autonomic nervous system physiology (HP:0012332) | 1.36994514 |
76 | Muscle fibrillation (HP:0010546) | 1.36921158 |
77 | Megalencephaly (HP:0001355) | 1.35791447 |
78 | Abnormality of the pupil (HP:0000615) | 1.35423221 |
79 | Abnormality of the anterior chamber (HP:0000593) | 1.33368208 |
80 | Photophobia (HP:0000613) | 1.32810585 |
81 | Scotoma (HP:0000575) | 1.31720461 |
82 | Hamartoma of the eye (HP:0010568) | 1.31435346 |
83 | Fibular hypoplasia (HP:0003038) | 1.30673200 |
84 | Narrow nasal bridge (HP:0000446) | 1.30018720 |
85 | Cerebral inclusion bodies (HP:0100314) | 1.27808238 |
86 | Protrusio acetabuli (HP:0003179) | 1.27366245 |
87 | Decreased lacrimation (HP:0000633) | 1.26275017 |
88 | Abnormality of the left ventricular outflow tract (HP:0011103) | 1.26111855 |
89 | Subaortic stenosis (HP:0001682) | 1.26111855 |
90 | Aortic aneurysm (HP:0004942) | 1.25392089 |
91 | Neoplasm of the liver (HP:0002896) | 1.24643535 |
92 | Hand muscle atrophy (HP:0009130) | 1.24469503 |
93 | Long toe (HP:0010511) | 1.24237719 |
94 | Aplasia cutis congenita (HP:0001057) | 1.23785052 |
95 | Myelomeningocele (HP:0002475) | 1.21811485 |
96 | Neoplasm of striated muscle (HP:0009728) | 1.20952548 |
97 | Supernumerary ribs (HP:0005815) | 1.20933621 |
98 | Vascular tortuosity (HP:0004948) | 1.20223114 |
99 | Visual hallucinations (HP:0002367) | 1.19169090 |
100 | Anterior segment dysgenesis (HP:0007700) | 1.18760364 |
101 | Decreased central vision (HP:0007663) | 1.18090649 |
102 | Spastic paraplegia (HP:0001258) | 1.17306340 |
103 | Ulnar deviation of finger (HP:0009465) | 1.16896758 |
104 | Poor head control (HP:0002421) | 1.16295974 |
105 | Hypermetropia (HP:0000540) | 1.14290208 |
106 | Intestinal polyposis (HP:0200008) | 1.13758723 |
107 | Morphological abnormality of the inner ear (HP:0011390) | 1.12193210 |
108 | Spinal muscular atrophy (HP:0007269) | 1.08989984 |
109 | Decreased motor nerve conduction velocity (HP:0003431) | 1.08856743 |
110 | Asymmetry of the thorax (HP:0001555) | 1.07777223 |
111 | Atelectasis (HP:0100750) | 1.06867438 |
112 | Overlapping toe (HP:0001845) | 1.05296788 |
113 | Intestinal polyp (HP:0005266) | 1.04809166 |
114 | Coarse hair (HP:0002208) | 1.04555081 |
115 | Macular degeneration (HP:0000608) | 1.04481881 |
116 | Tracheomalacia (HP:0002779) | 1.04114238 |
117 | Loss of speech (HP:0002371) | 1.03381936 |
118 | Paraplegia (HP:0010550) | 1.03124519 |
119 | Synostosis of carpal bones (HP:0005048) | 1.02760876 |
120 | Paraparesis (HP:0002385) | 1.02688611 |
121 | Absent frontal sinuses (HP:0002688) | 1.02391768 |
122 | Distal upper limb amyotrophy (HP:0007149) | 1.01918678 |
123 | Upper limb amyotrophy (HP:0009129) | 1.01918678 |
124 | Supernumerary bones of the axial skeleton (HP:0009144) | 1.01697748 |
125 | Neoplasm of the oral cavity (HP:0100649) | 0.99497787 |
126 | Proximal amyotrophy (HP:0007126) | 0.99407025 |
127 | Bladder diverticulum (HP:0000015) | 0.99206876 |
128 | Abnormality of glycolysis (HP:0004366) | 0.99063520 |
129 | Ovoid vertebral bodies (HP:0003300) | 0.99057983 |
130 | Premature rupture of membranes (HP:0001788) | 0.98027985 |
131 | Abnormality of the shoulder girdle musculature (HP:0001435) | 0.97660627 |
132 | Long clavicles (HP:0000890) | 0.96830816 |
133 | Neoplasm of the colon (HP:0100273) | 0.96652461 |
134 | Parkinsonism with favorable response to dopaminergic medication (HP:0002548) | 0.96024664 |
135 | Distal sensory impairment (HP:0002936) | 0.94224059 |
136 | Large for gestational age (HP:0001520) | 0.93729206 |
137 | Spastic paraparesis (HP:0002313) | 0.93419091 |
138 | Dyschromatopsia (HP:0007641) | 0.93367922 |
139 | Osteolytic defects of the phalanges of the hand (HP:0009771) | 0.92754766 |
140 | Osteolytic defects of the hand bones (HP:0009699) | 0.92754766 |
141 | Uterine leiomyosarcoma (HP:0002891) | 0.92572379 |
142 | Leiomyosarcoma (HP:0100243) | 0.92572379 |
143 | Skin nodule (HP:0200036) | 0.91494467 |
144 | Ulnar deviation of the hand or of fingers of the hand (HP:0001193) | 0.91330233 |
145 | Carpal synostosis (HP:0009702) | 0.91114096 |
146 | Leukodystrophy (HP:0002415) | 0.91113630 |
147 | Upper limb muscle weakness (HP:0003484) | 0.90006374 |
148 | Exostoses (HP:0100777) | 0.88584905 |
149 | Cutaneous finger syndactyly (HP:0010554) | 0.87712447 |
150 | Macroorchidism (HP:0000053) | 0.86085078 |
151 | Hypopigmented skin patches (HP:0001053) | 0.85461275 |
152 | Enlarged penis (HP:0000040) | 0.85151006 |
153 | Bladder carcinoma (HP:0002862) | 0.84853429 |
154 | Bladder neoplasm (HP:0009725) | 0.84853429 |
155 | Attenuation of retinal blood vessels (HP:0007843) | 0.84671368 |
156 | Joint stiffness (HP:0001387) | 0.84187183 |
157 | Deep venous thrombosis (HP:0002625) | 0.83079122 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MET | 5.70737858 |
2 | PDK2 | 4.51539311 |
3 | BMX | 3.99220595 |
4 | MARK3 | 3.87245269 |
5 | PKN2 | 3.66749630 |
6 | WEE1 | 2.96666927 |
7 | TRIB3 | 2.58649799 |
8 | CDK3 | 2.34639324 |
9 | BMPR2 | 2.32091729 |
10 | EPHA3 | 2.19485923 |
11 | ERBB3 | 2.12830364 |
12 | EIF2AK1 | 2.03846949 |
13 | MST1R | 13.3347730 |
14 | BMPR1B | 1.90730021 |
15 | TRIM28 | 1.88792625 |
16 | PRKCH | 1.86490959 |
17 | ACVR1B | 1.67426771 |
18 | SCYL2 | 1.58884967 |
19 | EIF2AK3 | 1.47574328 |
20 | SIK3 | 1.35974933 |
21 | TGFBR2 | 1.27189327 |
22 | DDR2 | 1.21568402 |
23 | GRK6 | 1.18310761 |
24 | PTK2B | 1.15785422 |
25 | GRK5 | 1.12589038 |
26 | LATS1 | 1.05363281 |
27 | PLK3 | 1.03239727 |
28 | MAP3K3 | 0.97743186 |
29 | NEK6 | 0.96000194 |
30 | FLT3 | 0.92329786 |
31 | PTK6 | 0.87284482 |
32 | PRKD1 | 0.85766343 |
33 | ABL2 | 0.84562481 |
34 | PLK1 | 0.84300897 |
35 | TTN | 0.82787499 |
36 | NEK1 | 0.81743223 |
37 | PRKD3 | 0.78622293 |
38 | GSK3A | 0.77774033 |
39 | DAPK3 | 0.77743434 |
40 | LRRK2 | 0.74850249 |
41 | MAPKAPK3 | 0.72005221 |
42 | BRSK1 | 0.71889515 |
43 | STK38L | 0.71885876 |
44 | ATR | 0.68417915 |
45 | CAMKK1 | 0.67226883 |
46 | CCNB1 | 0.63746877 |
47 | CSNK1G1 | 0.60769085 |
48 | CDK18 | 0.58904139 |
49 | RET | 0.58437249 |
50 | KSR2 | 0.56368719 |
51 | CSNK1G3 | 0.54061462 |
52 | ADRBK1 | 0.52175389 |
53 | CSNK1A1L | 0.52171457 |
54 | PIM1 | 0.51864860 |
55 | KSR1 | 0.50087114 |
56 | RPS6KB1 | 0.49654964 |
57 | BCR | 0.49426269 |
58 | TGFBR1 | 0.49390085 |
59 | CDK15 | 0.48425943 |
60 | FER | 0.48385572 |
61 | MATK | 0.48103567 |
62 | KIT | 0.47936584 |
63 | PAK4 | 0.47190847 |
64 | ATM | 0.46864133 |
65 | ILK | 0.42869800 |
66 | STK38 | 0.42074145 |
67 | EIF2AK2 | 0.42016317 |
68 | CDK11A | 0.42004401 |
69 | FGFR4 | 0.41958967 |
70 | CDK14 | 0.41667293 |
71 | CSNK1G2 | 0.41621221 |
72 | PDGFRA | 0.41186744 |
73 | CAMKK2 | 0.39630065 |
74 | ICK | 0.39404989 |
75 | RPS6KB2 | 0.39402579 |
76 | KDR | 0.39210440 |
77 | MAP3K9 | 0.38838975 |
78 | BUB1 | 0.38458256 |
79 | TBK1 | 0.36218146 |
80 | PRKG2 | 0.35889841 |
81 | RIPK1 | 0.34974657 |
82 | MAP3K13 | 0.33970842 |
83 | AKT2 | 0.33885913 |
84 | DYRK1A | 0.33586438 |
85 | CSNK1A1 | 0.32597389 |
86 | FRK | 0.31978866 |
87 | EEF2K | 0.31409258 |
88 | PINK1 | 0.31146103 |
89 | MAPK12 | 0.30471243 |
90 | PAK6 | 0.29419901 |
91 | PRKCE | 0.29070181 |
92 | MELK | 0.27576837 |
93 | INSR | 0.26668933 |
94 | PRKCZ | 0.25787797 |
95 | MAP2K1 | 0.24859225 |
96 | CDK6 | 0.24749462 |
97 | CDK7 | 0.24637257 |
98 | PRKD2 | 0.23688107 |
99 | NTRK1 | 0.23172467 |
100 | FGFR3 | 0.22810473 |
101 | CAMK1D | 0.21951000 |
102 | LMTK2 | 0.20728439 |
103 | EGFR | 0.20423153 |
104 | MAP3K8 | 0.20018828 |
105 | MAPK7 | 0.19458184 |
106 | DMPK | 0.19350273 |
107 | MAP3K11 | 0.18923883 |
108 | PLK4 | 0.18519876 |
109 | RAF1 | 0.18130173 |
110 | CAMK2A | 0.17632101 |
111 | NME2 | 0.16941327 |
112 | STK39 | 0.16399857 |
113 | CHUK | 0.16112724 |
114 | FGR | 0.14761052 |
115 | EPHB1 | 0.13700795 |
116 | STK4 | 0.13688633 |
117 | SGK3 | 0.13302127 |
118 | ARAF | 0.13239252 |
119 | CDC7 | 0.13200912 |
120 | IGF1R | 0.12541547 |
121 | TYRO3 | 0.12477227 |
122 | ALK | 0.12414549 |
123 | TLK1 | 0.12157280 |
124 | FGFR1 | 0.11759277 |
125 | PLK2 | 0.11609689 |
126 | PAK3 | 0.11392392 |
127 | LATS2 | 0.11344123 |
128 | RPS6KA1 | 0.11242814 |
129 | STK3 | 0.11208854 |
130 | PAK2 | 0.11101484 |
131 | SGK2 | 0.10981761 |
132 | FGFR2 | 0.10897560 |
133 | PDGFRB | 0.10831943 |
134 | ABL1 | 0.10626158 |
135 | CHEK2 | 0.10598719 |
136 | SRC | 0.10505361 |
137 | BRSK2 | 0.09036007 |
138 | PTK2 | 0.08731450 |
139 | CDK4 | 0.08540233 |
140 | BLK | 0.08256993 |
141 | MAPK3 | 0.08146173 |
142 | CSNK1D | 0.08139296 |
143 | DYRK1B | 0.07460393 |
144 | ZAK | 0.07223221 |
145 | MAP4K1 | 0.05812506 |
146 | MOS | 0.05681505 |
147 | PRKACB | 0.05438807 |
148 | TRPM7 | 0.05191701 |
149 | SGK223 | 0.05142391 |
150 | SGK494 | 0.05142391 |
151 | MAP3K2 | 0.04269014 |
152 | PRKAA2 | 0.04168779 |
153 | NEK9 | 0.03543755 |
154 | PRKCQ | 0.03477866 |
155 | PDK1 | 0.03212764 |
156 | MAP3K1 | 0.02615976 |
157 | ERBB2 | 0.02468828 |
158 | NEK2 | 0.01939623 |
159 | WNK4 | 0.01667168 |
Rank | Gene Set | Z-score |
---|---|---|
1 | * Tyrosine metabolism_Homo sapiens_hsa00350 | 7.96634349 |
2 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 4.66154560 |
3 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 4.13538239 |
4 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 3.45126288 |
5 | * Melanogenesis_Homo sapiens_hsa04916 | 3.24261159 |
6 | Non-homologous end-joining_Homo sapiens_hsa03450 | 3.19948071 |
7 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 3.10317167 |
8 | Galactose metabolism_Homo sapiens_hsa00052 | 2.57453351 |
9 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 2.43904995 |
10 | Melanoma_Homo sapiens_hsa05218 | 2.27288470 |
11 | Renal cell carcinoma_Homo sapiens_hsa05211 | 2.24910552 |
12 | Other glycan degradation_Homo sapiens_hsa00511 | 2.22669594 |
13 | Proteasome_Homo sapiens_hsa03050 | 2.09590689 |
14 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 2.07835531 |
15 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 2.07442054 |
16 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.94512226 |
17 | Protein export_Homo sapiens_hsa03060 | 1.94384163 |
18 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.93617724 |
19 | p53 signaling pathway_Homo sapiens_hsa04115 | 1.83990240 |
20 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 1.82353273 |
21 | Adherens junction_Homo sapiens_hsa04520 | 1.71644938 |
22 | Histidine metabolism_Homo sapiens_hsa00340 | 1.65758744 |
23 | Homologous recombination_Homo sapiens_hsa03440 | 1.62593773 |
24 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 1.61666828 |
25 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 1.57572149 |
26 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 1.54731038 |
27 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 1.51633571 |
28 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 1.50335612 |
29 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 1.49763392 |
30 | Cell cycle_Homo sapiens_hsa04110 | 1.47962430 |
31 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 1.47428422 |
32 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 1.37960236 |
33 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 1.36289619 |
34 | Glutathione metabolism_Homo sapiens_hsa00480 | 1.34059241 |
35 | Malaria_Homo sapiens_hsa05144 | 1.32470658 |
36 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 1.29450068 |
37 | Parkinsons disease_Homo sapiens_hsa05012 | 1.26650758 |
38 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.23504547 |
39 | Carbon metabolism_Homo sapiens_hsa01200 | 1.18346232 |
40 | Mismatch repair_Homo sapiens_hsa03430 | 1.17906933 |
41 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 1.17530450 |
42 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.16874748 |
43 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 1.14808808 |
44 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 1.14517452 |
45 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 1.14148477 |
46 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.13567395 |
47 | Lysosome_Homo sapiens_hsa04142 | 1.12088791 |
48 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.09689652 |
49 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 1.02460618 |
50 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.98733333 |
51 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.98252510 |
52 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.98071873 |
53 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.97313403 |
54 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 0.96705827 |
55 | Glioma_Homo sapiens_hsa05214 | 0.94946201 |
56 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 0.94704033 |
57 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.94190081 |
58 | Focal adhesion_Homo sapiens_hsa04510 | 0.91873065 |
59 | Alzheimers disease_Homo sapiens_hsa05010 | 0.89260582 |
60 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.86119944 |
61 | Axon guidance_Homo sapiens_hsa04360 | 0.84967685 |
62 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.84694561 |
63 | Alcoholism_Homo sapiens_hsa05034 | 0.82432921 |
64 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.82131751 |
65 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.80394230 |
66 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.78241674 |
67 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.78035043 |
68 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.77998291 |
69 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.77007935 |
70 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.74425230 |
71 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.73162885 |
72 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.72950080 |
73 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.71040792 |
74 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.70673466 |
75 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.69603324 |
76 | Bile secretion_Homo sapiens_hsa04976 | 0.69570852 |
77 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.69102279 |
78 | Thyroid cancer_Homo sapiens_hsa05216 | 0.67258703 |
79 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.67248731 |
80 | * Metabolic pathways_Homo sapiens_hsa01100 | 0.67190020 |
81 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.65946635 |
82 | Huntingtons disease_Homo sapiens_hsa05016 | 0.65587805 |
83 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.64220458 |
84 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.62226138 |
85 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 0.59246677 |
86 | Bladder cancer_Homo sapiens_hsa05219 | 0.58413163 |
87 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.57894665 |
88 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.56376976 |
89 | DNA replication_Homo sapiens_hsa03030 | 0.55834396 |
90 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.55401917 |
91 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.54537881 |
92 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.54123074 |
93 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.54059718 |
94 | Lysine degradation_Homo sapiens_hsa00310 | 0.54043214 |
95 | Endometrial cancer_Homo sapiens_hsa05213 | 0.53086261 |
96 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.52471744 |
97 | Prostate cancer_Homo sapiens_hsa05215 | 0.52459387 |
98 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.51867141 |
99 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.51462050 |
100 | Retinol metabolism_Homo sapiens_hsa00830 | 0.49466127 |
101 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.49369802 |
102 | Osteoclast differentiation_Homo sapiens_hsa04380 | 0.48387552 |
103 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.47685100 |
104 | ABC transporters_Homo sapiens_hsa02010 | 0.47020136 |
105 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.46881395 |
106 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 0.46331345 |
107 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.46146464 |
108 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.45828805 |
109 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.45572069 |
110 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.45269825 |
111 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.44661771 |
112 | Endocytosis_Homo sapiens_hsa04144 | 0.44494169 |
113 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.44028961 |
114 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 0.43991393 |
115 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.42170754 |
116 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.40457725 |
117 | Tight junction_Homo sapiens_hsa04530 | 0.37468815 |
118 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.37065991 |
119 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.36646865 |
120 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.34830163 |
121 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.32237626 |
122 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.31820994 |
123 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 0.31377370 |
124 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.31319415 |
125 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.30264939 |
126 | Phagosome_Homo sapiens_hsa04145 | 0.29971267 |
127 | Insulin resistance_Homo sapiens_hsa04931 | 0.27756967 |
128 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.27575926 |
129 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.27377365 |
130 | Hepatitis B_Homo sapiens_hsa05161 | 0.26584920 |
131 | Peroxisome_Homo sapiens_hsa04146 | 0.26487658 |
132 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.26230015 |
133 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.25746684 |
134 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.24135441 |
135 | Sulfur relay system_Homo sapiens_hsa04122 | 0.24001063 |
136 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.23908440 |
137 | Pathways in cancer_Homo sapiens_hsa05200 | 0.23759741 |
138 | Colorectal cancer_Homo sapiens_hsa05210 | 0.23580338 |
139 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.23574390 |
140 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.23198241 |
141 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.22882779 |
142 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.21884716 |
143 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.21421068 |
144 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.21199458 |
145 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.20924777 |
146 | PI3K-Akt signaling pathway_Homo sapiens_hsa04151 | 0.20239467 |
147 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.20173860 |
148 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.18130911 |
149 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.17120708 |
150 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 0.16836550 |
151 | Mineral absorption_Homo sapiens_hsa04978 | 0.15636376 |
152 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.15244226 |
153 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.14565943 |
154 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.13628210 |