Rank | Gene Set | Z-score |
---|---|---|
1 | pre-miRNA processing (GO:0031054) | 4.93082636 |
2 | DNA unwinding involved in DNA replication (GO:0006268) | 4.68533886 |
3 | regulation of translational fidelity (GO:0006450) | 4.35002903 |
4 | nuclear pore complex assembly (GO:0051292) | 4.34569284 |
5 | protein localization to kinetochore (GO:0034501) | 4.28427064 |
6 | heterochromatin organization (GO:0070828) | 4.27233924 |
7 | nuclear pore organization (GO:0006999) | 4.23958834 |
8 | Golgi transport vesicle coating (GO:0048200) | 4.18416337 |
9 | COPI coating of Golgi vesicle (GO:0048205) | 4.18416337 |
10 | RNA stabilization (GO:0043489) | 4.02411868 |
11 | mRNA stabilization (GO:0048255) | 4.02411868 |
12 | regulation of mammary gland epithelial cell proliferation (GO:0033599) | 3.93514369 |
13 | negative regulation of erythrocyte differentiation (GO:0045647) | 3.89826414 |
14 | proline biosynthetic process (GO:0006561) | 3.83014276 |
15 | folic acid-containing compound biosynthetic process (GO:0009396) | 3.81896744 |
16 | regulation of gene silencing by RNA (GO:0060966) | 3.78088801 |
17 | regulation of posttranscriptional gene silencing (GO:0060147) | 3.78088801 |
18 | regulation of gene silencing by miRNA (GO:0060964) | 3.78088801 |
19 | negative regulation of histone methylation (GO:0031061) | 3.76875084 |
20 | peptidyl-lysine dimethylation (GO:0018027) | 3.76033346 |
21 | regulation of translational termination (GO:0006449) | 3.69049221 |
22 | spliceosomal tri-snRNP complex assembly (GO:0000244) | 3.60734949 |
23 | sister chromatid segregation (GO:0000819) | 3.60638911 |
24 | chromatin assembly (GO:0031497) | 3.60226248 |
25 | activation of Rac GTPase activity (GO:0032863) | 3.56375290 |
26 | protein localization to endosome (GO:0036010) | 3.52540563 |
27 | positive regulation of histone deacetylation (GO:0031065) | 3.48761249 |
28 | dosage compensation (GO:0007549) | 3.47372680 |
29 | mitotic nuclear envelope disassembly (GO:0007077) | 3.42239563 |
30 | regulation of histone H3-K27 methylation (GO:0061085) | 3.41764846 |
31 | protein localization to chromosome, centromeric region (GO:0071459) | 3.41224814 |
32 | pentose-phosphate shunt (GO:0006098) | 3.41213669 |
33 | DNA duplex unwinding (GO:0032508) | 3.41041852 |
34 | mitotic sister chromatid segregation (GO:0000070) | 3.40106409 |
35 | DNA geometric change (GO:0032392) | 3.37926588 |
36 | peptidyl-arginine omega-N-methylation (GO:0035247) | 3.35188414 |
37 | regulation of attachment of spindle microtubules to kinetochore (GO:0051988) | 3.34572186 |
38 | maternal placenta development (GO:0001893) | 3.31148469 |
39 | regulation of histone H3-K9 methylation (GO:0051570) | 3.30167697 |
40 | glucocorticoid receptor signaling pathway (GO:0042921) | 3.28800019 |
41 | regulation of NFAT protein import into nucleus (GO:0051532) | 3.28627445 |
42 | membrane disassembly (GO:0030397) | 3.27819612 |
43 | nuclear envelope disassembly (GO:0051081) | 3.27819612 |
44 | regulation of hippo signaling (GO:0035330) | 3.27608879 |
45 | DNA replication-dependent nucleosome organization (GO:0034723) | 3.25637968 |
46 | DNA replication-dependent nucleosome assembly (GO:0006335) | 3.25637968 |
47 | regulation of RNA export from nucleus (GO:0046831) | 3.24619818 |
48 | regulation of early endosome to late endosome transport (GO:2000641) | 3.24362461 |
49 | mitotic G1 DNA damage checkpoint (GO:0031571) | 3.22392362 |
50 | regulation of glucose import in response to insulin stimulus (GO:2001273) | 3.21165642 |
51 | establishment of apical/basal cell polarity (GO:0035089) | 3.19497586 |
52 | 3-UTR-mediated mRNA stabilization (GO:0070935) | 3.18815151 |
53 | NLS-bearing protein import into nucleus (GO:0006607) | 3.18041302 |
54 | mitotic chromosome condensation (GO:0007076) | 3.16859270 |
55 | * negative regulation of mRNA splicing, via spliceosome (GO:0048025) | 3.14640736 |
56 | regulation of sister chromatid cohesion (GO:0007063) | 3.13185757 |
57 | intracellular estrogen receptor signaling pathway (GO:0030520) | 3.07680674 |
58 | positive regulation of SMAD protein import into nucleus (GO:0060391) | 3.06335751 |
59 | retrograde vesicle-mediated transport, Golgi to ER (GO:0006890) | 3.06069278 |
60 | regulation of mRNA stability (GO:0043488) | 3.06035220 |
61 | pore complex assembly (GO:0046931) | 3.05968947 |
62 | cellular protein complex localization (GO:0034629) | 3.05673455 |
63 | histone H2A monoubiquitination (GO:0035518) | 3.05407636 |
64 | apoptotic process involved in morphogenesis (GO:0060561) | 3.04431694 |
65 | ribosomal small subunit biogenesis (GO:0042274) | 3.04024534 |
66 | protein complex localization (GO:0031503) | 3.02512517 |
67 | peptidyl-arginine methylation (GO:0018216) | 3.01913640 |
68 | peptidyl-arginine N-methylation (GO:0035246) | 3.01913640 |
69 | protein retention in ER lumen (GO:0006621) | 3.01061945 |
70 | polarized epithelial cell differentiation (GO:0030859) | 2.99409562 |
71 | mitotic sister chromatid cohesion (GO:0007064) | 2.99117573 |
72 | maintenance of protein localization in endoplasmic reticulum (GO:0035437) | 2.98904849 |
73 | positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling | 2.98138623 |
74 | alternative mRNA splicing, via spliceosome (GO:0000380) | 2.96863171 |
75 | formation of translation preinitiation complex (GO:0001731) | 2.95314973 |
76 | trophectodermal cell differentiation (GO:0001829) | 2.92550435 |
77 | cell-substrate junction assembly (GO:0007044) | 2.91337551 |
78 | NADPH regeneration (GO:0006740) | 2.90558229 |
79 | * negative regulation of RNA splicing (GO:0033119) | 2.90482350 |
80 | positive regulation of chromosome segregation (GO:0051984) | 2.89301841 |
81 | IMP biosynthetic process (GO:0006188) | 2.87904173 |
82 | glucose catabolic process (GO:0006007) | 2.86827471 |
83 | protein export from nucleus (GO:0006611) | 2.86030296 |
84 | mitotic G1/S transition checkpoint (GO:0044819) | 2.85871522 |
85 | regulation of RNA stability (GO:0043487) | 2.85415590 |
86 | embryonic process involved in female pregnancy (GO:0060136) | 2.84117923 |
87 | negative regulation of cell size (GO:0045792) | 2.82575528 |
88 | adherens junction assembly (GO:0034333) | 2.79821713 |
89 | paraxial mesoderm development (GO:0048339) | 2.78101933 |
90 | nuclear envelope organization (GO:0006998) | 2.77394919 |
91 | DNA topological change (GO:0006265) | 2.77157098 |
92 | regulation of chromatin binding (GO:0035561) | 2.73621531 |
93 | cytoplasmic mRNA processing body assembly (GO:0033962) | 2.73408790 |
94 | protein-DNA complex disassembly (GO:0032986) | 2.72205472 |
95 | nucleosome disassembly (GO:0006337) | 2.72205472 |
96 | glucose 6-phosphate metabolic process (GO:0051156) | 2.70579763 |
97 | mannose metabolic process (GO:0006013) | 2.70084404 |
98 | planar cell polarity pathway involved in neural tube closure (GO:0090179) | 2.69533112 |
99 | positive regulation of Cdc42 GTPase activity (GO:0043089) | 2.68320600 |
100 | regulation of nucleobase-containing compound transport (GO:0032239) | 2.67734184 |
101 | DNA replication initiation (GO:0006270) | 2.67596807 |
102 | gene silencing (GO:0016458) | 2.66348819 |
103 | chromatin silencing (GO:0006342) | 2.66321133 |
104 | G1 DNA damage checkpoint (GO:0044783) | 2.66296868 |
105 | corticosteroid receptor signaling pathway (GO:0031958) | 2.66220686 |
106 | DNA strand elongation involved in DNA replication (GO:0006271) | 2.65414873 |
107 | chromosome condensation (GO:0030261) | 2.64018649 |
108 | modulation by symbiont of host cellular process (GO:0044068) | 2.63930231 |
109 | DNA strand elongation (GO:0022616) | 2.62721869 |
110 | positive regulation of gene expression, epigenetic (GO:0045815) | 2.61878997 |
111 | positive regulation of type I interferon-mediated signaling pathway (GO:0060340) | 2.61565626 |
112 | regulation of SMAD protein import into nucleus (GO:0060390) | 2.60983254 |
113 | epithelial cell differentiation involved in prostate gland development (GO:0060742) | 2.60094011 |
114 | * negative regulation of mRNA metabolic process (GO:1903312) | 2.59888169 |
115 | modulation by virus of host process (GO:0019054) | 2.59587739 |
116 | * negative regulation of mRNA processing (GO:0050686) | 2.59121240 |
117 | regulation of establishment of planar polarity involved in neural tube closure (GO:0090178) | 2.59055778 |
118 | positive regulation of nuclease activity (GO:0032075) | 2.57031613 |
119 | activation of signaling protein activity involved in unfolded protein response (GO:0006987) | 2.56798223 |
120 | negative regulation of gene expression, epigenetic (GO:0045814) | 2.56245069 |
121 | establishment or maintenance of monopolar cell polarity (GO:0061339) | 2.53744191 |
122 | establishment of monopolar cell polarity (GO:0061162) | 2.53744191 |
123 | DNA conformation change (GO:0071103) | 2.53302380 |
124 | cell-substrate adherens junction assembly (GO:0007045) | 2.53182125 |
125 | focal adhesion assembly (GO:0048041) | 2.53182125 |
126 | negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471) | 2.52803677 |
127 | nuclear-transcribed mRNA poly(A) tail shortening (GO:0000289) | 2.52289439 |
128 | regulation of gene silencing (GO:0060968) | 2.51010046 |
129 | gene silencing by RNA (GO:0031047) | 2.50437192 |
130 | cellular response to epidermal growth factor stimulus (GO:0071364) | 2.50289387 |
131 | positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling | 2.49503501 |
132 | regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway | 2.49503501 |
133 | negative regulation of histone modification (GO:0031057) | 2.48713254 |
134 | cytoskeletal anchoring at plasma membrane (GO:0007016) | 2.48210438 |
135 | negative regulation of viral release from host cell (GO:1902187) | 2.47400901 |
136 | pinocytosis (GO:0006907) | 2.47061014 |
137 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 2.46804860 |
138 | positive regulation of protein deacetylation (GO:0090312) | 2.46773206 |
139 | hippo signaling (GO:0035329) | 2.46191036 |
140 | IMP metabolic process (GO:0046040) | 2.45470784 |
141 | chromatin assembly or disassembly (GO:0006333) | 2.45116541 |
142 | T cell apoptotic process (GO:0070231) | 2.45079978 |
143 | histone arginine methylation (GO:0034969) | 2.44633817 |
144 | stress fiber assembly (GO:0043149) | 2.44336905 |
145 | histone H4-K12 acetylation (GO:0043983) | 2.44334556 |
146 | protein localization to microtubule (GO:0035372) | 2.44324739 |
147 | histone H3-K36 demethylation (GO:0070544) | 2.43726475 |
148 | proline metabolic process (GO:0006560) | 2.42591413 |
149 | response to epidermal growth factor (GO:0070849) | 2.41324002 |
150 | response to laminar fluid shear stress (GO:0034616) | 2.41307318 |
151 | positive regulation of blood vessel endothelial cell migration (GO:0043536) | 2.39715874 |
152 | basement membrane organization (GO:0071711) | 2.36912725 |
153 | semaphorin-plexin signaling pathway (GO:0071526) | 2.36352676 |
154 | regulation of nuclease activity (GO:0032069) | 2.35691004 |
155 | nuclear envelope reassembly (GO:0031468) | 2.34519359 |
Rank | Gene Set | Z-score |
---|---|---|
1 | E2F7_22180533_ChIP-Seq_HELA_Human | 6.89045241 |
2 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 4.84370424 |
3 | MYC_22102868_ChIP-Seq_BL_Human | 3.82429480 |
4 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 3.75104935 |
5 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 3.28012429 |
6 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 2.57556516 |
7 | VDR_21846776_ChIP-Seq_THP-1_Human | 2.50871967 |
8 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 2.46239070 |
9 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.27007506 |
10 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 2.24401709 |
11 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 2.18778277 |
12 | KDM2B_26808549_Chip-Seq_DND41_Human | 2.17323586 |
13 | * TCF7_22412390_ChIP-Seq_EML_Mouse | 2.14941415 |
14 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 2.13780145 |
15 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 2.06172920 |
16 | * KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 1.97287136 |
17 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.95707344 |
18 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.95172956 |
19 | ZFP281_18358816_ChIP-ChIP_MESCs_Mouse | 1.94587349 |
20 | * ELK3_25401928_ChIP-Seq_HUVEC_Human | 1.89989795 |
21 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 1.88996045 |
22 | SMAD1_18555785_ChIP-Seq_MESCs_Mouse | 1.87568414 |
23 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 1.84251017 |
24 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 1.78737762 |
25 | * ZFP281_18757296_ChIP-ChIP_E14_Mouse | 1.74351625 |
26 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 1.72561208 |
27 | ZFP281_27345836_Chip-Seq_ESCs_Mouse | 1.67012943 |
28 | UTX_26944678_Chip-Seq_JUKART_Human | 1.64854301 |
29 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.61878562 |
30 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.59124961 |
31 | MAF_26560356_Chip-Seq_TH1_Human | 1.59005818 |
32 | * KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 1.55529878 |
33 | ZNF263_19887448_ChIP-Seq_K562_Human | 1.55006441 |
34 | KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.54891431 |
35 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 1.54533712 |
36 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.54051774 |
37 | ZIC3_20872845_ChIP-ChIP_MESCs_Mouse | 1.49295164 |
38 | CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat | 1.48785109 |
39 | EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.48537220 |
40 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 1.47674817 |
41 | * XRN2_22483619_ChIP-Seq_HELA_Human | 1.45586527 |
42 | KDM2B_26808549_Chip-Seq_JURKAT_Human | 1.45254427 |
43 | LXR_22292898_ChIP-Seq_THP-1_Human | 1.43825523 |
44 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.41794857 |
45 | P300_27058665_Chip-Seq_ZR-75-30cells_Human | 1.40797759 |
46 | CLOCK_20551151_ChIP-Seq_293T_Human | 1.38649986 |
47 | DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 1.37317012 |
48 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 1.36746506 |
49 | * RACK7_27058665_Chip-Seq_MCF-7_Human | 1.36171523 |
50 | * MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.35741944 |
51 | TET1_21451524_ChIP-Seq_MESCs_Mouse | 1.31868652 |
52 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 1.31631037 |
53 | * NCOR1_26117541_ChIP-Seq_K562_Human | 1.29785742 |
54 | SMAD3_22036565_ChIP-Seq_ESCs_Mouse | 1.29731406 |
55 | SALL4_18804426_ChIP-ChIP_MESCs_Mouse | 1.28894730 |
56 | HIF1A_21447827_ChIP-Seq_MCF-7_Human | 1.28865278 |
57 | KLF4_18358816_ChIP-ChIP_MESCs_Mouse | 1.28735671 |
58 | * ATF3_27146783_Chip-Seq_COLON_Human | 1.28597484 |
59 | KLF4_18555785_ChIP-Seq_MESCs_Mouse | 1.27970245 |
60 | UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human | 1.27853129 |
61 | KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.26510594 |
62 | * AR_21909140_ChIP-Seq_LNCAP_Human | 1.25743997 |
63 | * CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 1.25205277 |
64 | CTCF_27219007_Chip-Seq_ERYTHROID_Human | 1.24083840 |
65 | * RUNX2_24764292_ChIP-Seq_MC3T3_Mouse | 1.23432614 |
66 | * KDM5A_27292631_Chip-Seq_BREAST_Human | 1.23102383 |
67 | DMRT1_23473982_ChIP-Seq_TESTES_Mouse | 1.22633402 |
68 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 1.21801672 |
69 | KLF2_18264089_ChIP-ChIP_MESCs_Mouse | 1.21594527 |
70 | KLF5_18264089_ChIP-ChIP_MESCs_Mouse | 1.21594527 |
71 | KLF4_18264089_ChIP-ChIP_MESCs_Mouse | 1.21594527 |
72 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.21213905 |
73 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.20275825 |
74 | * ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.20098665 |
75 | SA1_27219007_Chip-Seq_ERYTHROID_Human | 1.19116192 |
76 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.18216417 |
77 | HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse | 1.17904312 |
78 | * EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human | 1.17643494 |
79 | NANOG_21062744_ChIP-ChIP_HESCs_Human | 1.15907645 |
80 | * VDR_24763502_ChIP-Seq_THP-1_Human | 1.15198775 |
81 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 1.12937615 |
82 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.12218197 |
83 | KDM2B_26808549_Chip-Seq_K562_Human | 1.11980513 |
84 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.11735700 |
85 | TCF3_18692474_ChIP-Seq_MEFs_Mouse | 1.11368553 |
86 | * RUNX1_22412390_ChIP-Seq_EML_Mouse | 1.11161569 |
87 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 1.10876486 |
88 | MAF_26560356_Chip-Seq_TH2_Human | 1.10796673 |
89 | * CHD1_26751641_Chip-Seq_LNCaP_Human | 1.10766925 |
90 | CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse | 1.10085017 |
91 | * WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse | 1.09574943 |
92 | SREBP2_21459322_ChIP-Seq_LIVER_Mouse | 1.09037777 |
93 | GATA1_22383799_ChIP-Seq_G1ME_Mouse | 1.08940196 |
94 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.08291816 |
95 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.06684208 |
96 | TCF3_18467660_ChIP-ChIP_MESCs_Mouse | 1.06669549 |
97 | CREB1_26743006_Chip-Seq_LNCaP_Human | 1.06623950 |
98 | ZFX_18555785_ChIP-Seq_MESCs_Mouse | 1.04661771 |
99 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.04190089 |
100 | SMC4_20622854_ChIP-Seq_HELA_Human | 1.04127006 |
101 | * TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 1.04122301 |
102 | PKCTHETA_26484144_Chip-Seq_BREAST_Human | 1.03615154 |
103 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.03474694 |
104 | ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.02818452 |
105 | TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 1.02778778 |
106 | TP53_22127205_ChIP-Seq_IMR90_Human | 1.02380379 |
107 | CNOT3_19339689_ChIP-ChIP_MESCs_Mouse | 1.02156234 |
108 | NANOG_18700969_ChIP-ChIP_MESCs_Mouse | 1.02023100 |
109 | MYB_26560356_Chip-Seq_TH1_Human | 1.01460591 |
110 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 1.01373380 |
111 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.01189603 |
112 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 1.00555458 |
113 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 0.99792208 |
114 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 0.99469942 |
115 | NANOG_18347094_ChIP-ChIP_MESCs_Mouse | 0.98843892 |
116 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 0.97209918 |
117 | NR0B1_18358816_ChIP-ChIP_MESCs_Mouse | 0.97023227 |
118 | P68_20966046_ChIP-Seq_HELA_Human | 0.96881307 |
119 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 0.95828745 |
120 | CREB1_26743006_Chip-Seq_LNCaP-abl_Human | 0.95398816 |
121 | TFEB_21752829_ChIP-Seq_HELA_Human | 0.94502221 |
122 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 0.94490925 |
123 | * MYB_26560356_Chip-Seq_TH2_Human | 0.93660214 |
124 | TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse | 0.93592657 |
125 | UBF1/2_26484160_Chip-Seq_HMECs_Human | 0.92097728 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0003705_abnormal_hypodermis_morpholog | 4.08229771 |
2 | MP0010352_gastrointestinal_tract_polyps | 3.31260718 |
3 | MP0005076_abnormal_cell_differentiation | 3.28349301 |
4 | MP0005451_abnormal_body_composition | 2.74487953 |
5 | MP0003111_abnormal_nucleus_morphology | 2.69685373 |
6 | MP0009278_abnormal_bone_marrow | 2.41517284 |
7 | MP0004957_abnormal_blastocyst_morpholog | 2.35400980 |
8 | MP0010234_abnormal_vibrissa_follicle | 2.27583470 |
9 | MP0001730_embryonic_growth_arrest | 2.25272531 |
10 | MP0003077_abnormal_cell_cycle | 2.22872688 |
11 | MP0010094_abnormal_chromosome_stability | 2.17717860 |
12 | MP0003300_gastrointestinal_ulcer | 2.17076857 |
13 | MP0010307_abnormal_tumor_latency | 2.14495538 |
14 | MP0000537_abnormal_urethra_morphology | 2.09522796 |
15 | MP0004197_abnormal_fetal_growth/weight/ | 2.06564026 |
16 | MP0001849_ear_inflammation | 2.03862074 |
17 | MP0003303_peritoneal_inflammation | 2.01724338 |
18 | MP0003693_abnormal_embryo_hatching | 2.00701246 |
19 | MP0003566_abnormal_cell_adhesion | 1.97655575 |
20 | MP0003123_paternal_imprinting | 1.97115511 |
21 | MP0000350_abnormal_cell_proliferation | 1.96792860 |
22 | MP0004858_abnormal_nervous_system | 1.90441269 |
23 | MP0002084_abnormal_developmental_patter | 1.87416138 |
24 | MP0005380_embryogenesis_phenotype | 1.82471069 |
25 | MP0001672_abnormal_embryogenesis/_devel | 1.82471069 |
26 | MP0000733_abnormal_muscle_development | 1.77783212 |
27 | MP0002796_impaired_skin_barrier | 1.76878001 |
28 | MP0005058_abnormal_lysosome_morphology | 1.76855257 |
29 | MP0002086_abnormal_extraembryonic_tissu | 1.74967979 |
30 | MP0009053_abnormal_anal_canal | 1.74534805 |
31 | MP0003984_embryonic_growth_retardation | 1.73649783 |
32 | MP0008057_abnormal_DNA_replication | 1.73514332 |
33 | MP0002085_abnormal_embryonic_tissue | 1.73184390 |
34 | MP0002088_abnormal_embryonic_growth/wei | 1.72361822 |
35 | MP0010030_abnormal_orbit_morphology | 1.72070330 |
36 | MP0004185_abnormal_adipocyte_glucose | 1.72001790 |
37 | MP0008260_abnormal_autophagy | 1.70938973 |
38 | MP0001697_abnormal_embryo_size | 1.65775963 |
39 | MP0000678_abnormal_parathyroid_gland | 1.62324363 |
40 | MP0004808_abnormal_hematopoietic_stem | 1.61594123 |
41 | MP0002396_abnormal_hematopoietic_system | 1.53917992 |
42 | MP0002080_prenatal_lethality | 1.53686141 |
43 | MP0008961_abnormal_basal_metabolism | 1.51808622 |
44 | MP0002653_abnormal_ependyma_morphology | 1.49593319 |
45 | MP0005409_darkened_coat_color | 1.46730439 |
46 | MP0002877_abnormal_melanocyte_morpholog | 1.34482476 |
47 | MP0000428_abnormal_craniofacial_morphol | 1.34421826 |
48 | MP0002249_abnormal_larynx_morphology | 1.34341751 |
49 | MP0008007_abnormal_cellular_replicative | 1.33840347 |
50 | MP0003119_abnormal_digestive_system | 1.33832191 |
51 | MP0005023_abnormal_wound_healing | 1.33363351 |
52 | MP0005623_abnormal_meninges_morphology | 1.31330827 |
53 | MP0003567_abnormal_fetal_cardiomyocyte | 1.28193803 |
54 | MP0003283_abnormal_digestive_organ | 1.26563551 |
55 | MP0003115_abnormal_respiratory_system | 1.24914429 |
56 | MP0000703_abnormal_thymus_morphology | 1.23339614 |
57 | MP0001915_intracranial_hemorrhage | 1.23098624 |
58 | MP0009672_abnormal_birth_weight | 1.21266652 |
59 | MP0002060_abnormal_skin_morphology | 1.21262824 |
60 | MP0003121_genomic_imprinting | 1.21243387 |
61 | MP0003436_decreased_susceptibility_to | 1.20487096 |
62 | MP0002925_abnormal_cardiovascular_devel | 1.18047874 |
63 | MP0000490_abnormal_crypts_of | 1.14333601 |
64 | MP0002697_abnormal_eye_size | 1.14131911 |
65 | MP0002092_abnormal_eye_morphology | 1.10138211 |
66 | MP0003091_abnormal_cell_migration | 1.07750989 |
67 | MP0009703_decreased_birth_body | 1.07673369 |
68 | MP0003890_abnormal_embryonic-extraembry | 1.06478869 |
69 | MP0002009_preneoplasia | 1.05809951 |
70 | MP0008770_decreased_survivor_rate | 1.05657080 |
71 | MP0004233_abnormal_muscle_weight | 1.05070651 |
72 | MP0005397_hematopoietic_system_phenotyp | 1.02995915 |
73 | MP0001545_abnormal_hematopoietic_system | 1.02995915 |
74 | MP0002019_abnormal_tumor_incidence | 1.00581354 |
75 | MP0008932_abnormal_embryonic_tissue | 0.99154173 |
76 | MP0003191_abnormal_cellular_cholesterol | 0.99100054 |
77 | MP0000313_abnormal_cell_death | 0.98619563 |
78 | MP0006054_spinal_hemorrhage | 0.98543453 |
79 | MP0003172_abnormal_lysosome_physiology | 0.97939869 |
80 | MP0001873_stomach_inflammation | 0.97016716 |
81 | MP0009840_abnormal_foam_cell | 0.96107507 |
82 | MP0002111_abnormal_tail_morphology | 0.95138327 |
83 | MP0003935_abnormal_craniofacial_develop | 0.95129583 |
84 | MP0001293_anophthalmia | 0.95128584 |
85 | MP0001216_abnormal_epidermal_layer | 0.94709016 |
86 | MP0002398_abnormal_bone_marrow | 0.94674996 |
87 | MP0010630_abnormal_cardiac_muscle | 0.94310456 |
88 | MP0003453_abnormal_keratinocyte_physiol | 0.91121601 |
89 | MP0009931_abnormal_skin_appearance | 0.90618528 |
90 | MP0004272_abnormal_basement_membrane | 0.90081604 |
91 | MP0001346_abnormal_lacrimal_gland | 0.87827302 |
92 | MP0003763_abnormal_thymus_physiology | 0.87058852 |
93 | MP0002722_abnormal_immune_system | 0.86716489 |
94 | MP0001348_abnormal_lacrimal_gland | 0.85973030 |
95 | MP0000266_abnormal_heart_morphology | 0.85963197 |
96 | MP0005666_abnormal_adipose_tissue | 0.85685450 |
97 | MP0004264_abnormal_extraembryonic_tissu | 0.85486889 |
98 | MP0005384_cellular_phenotype | 0.85314196 |
99 | MP0000569_abnormal_digit_pigmentation | 0.84037553 |
100 | MP0000477_abnormal_intestine_morphology | 0.83488757 |
101 | MP0009333_abnormal_splenocyte_physiolog | 0.83297873 |
102 | MP0000685_abnormal_immune_system | 0.83077156 |
103 | MP0003385_abnormal_body_wall | 0.82373794 |
104 | MP0004947_skin_inflammation | 0.81892739 |
105 | MP0000747_muscle_weakness | 0.81649786 |
106 | MP0005375_adipose_tissue_phenotype | 0.81604691 |
107 | MP0002932_abnormal_joint_morphology | 0.81183247 |
108 | MP0001784_abnormal_fluid_regulation | 0.80261377 |
109 | MP0008438_abnormal_cutaneous_collagen | 0.80218676 |
110 | MP0005621_abnormal_cell_physiology | 0.79445049 |
111 | MP0000432_abnormal_head_morphology | 0.78794231 |
112 | MP0003329_amyloid_beta_deposits | 0.78618023 |
113 | MP0000003_abnormal_adipose_tissue | 0.77815994 |
114 | MP0003861_abnormal_nervous_system | 0.77265020 |
115 | MP0005501_abnormal_skin_physiology | 0.77157533 |
116 | MP0000534_abnormal_ureter_morphology | 0.76194823 |
117 | MP0002089_abnormal_postnatal_growth/wei | 0.75794903 |
118 | MP0005187_abnormal_penis_morphology | 0.73010095 |
119 | MP0000689_abnormal_spleen_morphology | 0.73009799 |
120 | MP0000759_abnormal_skeletal_muscle | 0.72899491 |
121 | MP0003221_abnormal_cardiomyocyte_apopto | 0.72466418 |
122 | MP0003315_abnormal_perineum_morphology | 0.71705377 |
123 | MP0003942_abnormal_urinary_system | 0.70931403 |
124 | MP0002098_abnormal_vibrissa_morphology | 0.69636277 |
125 | MP0000858_altered_metastatic_potential | 0.68956518 |
126 | MP0004087_abnormal_muscle_fiber | 0.68766622 |
127 | MP0000467_abnormal_esophagus_morphology | 0.68766189 |
128 | MP0004782_abnormal_surfactant_physiolog | 0.68594824 |
129 | MP0005257_abnormal_intraocular_pressure | 0.68271221 |
130 | MP0000750_abnormal_muscle_regeneration | 0.67712715 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Hyperacusis (HP:0010780) | 3.64733723 |
2 | Ependymoma (HP:0002888) | 3.41106175 |
3 | Cerebral aneurysm (HP:0004944) | 3.12274522 |
4 | Short 4th metacarpal (HP:0010044) | 2.90266259 |
5 | Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042) | 2.90266259 |
6 | Renal duplication (HP:0000075) | 2.86310121 |
7 | Pseudobulbar signs (HP:0002200) | 2.86153756 |
8 | Abnormality of the astrocytes (HP:0100707) | 2.84823236 |
9 | Astrocytoma (HP:0009592) | 2.84823236 |
10 | Broad face (HP:0000283) | 2.82644550 |
11 | Ulnar bowing (HP:0003031) | 2.80708543 |
12 | Shallow orbits (HP:0000586) | 2.78112843 |
13 | Premature rupture of membranes (HP:0001788) | 2.70634778 |
14 | Distal lower limb amyotrophy (HP:0008944) | 2.69007411 |
15 | Increased nuchal translucency (HP:0010880) | 2.63627012 |
16 | Increased density of long bones (HP:0006392) | 2.62612734 |
17 | Long palpebral fissure (HP:0000637) | 2.59151981 |
18 | Selective tooth agenesis (HP:0001592) | 2.56941170 |
19 | Asymmetry of the thorax (HP:0001555) | 2.54025228 |
20 | Elfin facies (HP:0004428) | 2.44884470 |
21 | Abnormality of the 4th metacarpal (HP:0010012) | 2.42308485 |
22 | Increased connective tissue (HP:0009025) | 2.42071170 |
23 | Renovascular hypertension (HP:0100817) | 2.39334219 |
24 | Insomnia (HP:0100785) | 2.38754871 |
25 | Abnormality of the Achilles tendon (HP:0005109) | 2.36463024 |
26 | Overriding aorta (HP:0002623) | 2.30896370 |
27 | Protrusio acetabuli (HP:0003179) | 2.29472947 |
28 | Flat acetabular roof (HP:0003180) | 2.28995769 |
29 | Deviation of the thumb (HP:0009603) | 2.28586151 |
30 | Obstructive sleep apnea (HP:0002870) | 2.28454417 |
31 | Vertebral compression fractures (HP:0002953) | 2.28315444 |
32 | Basal cell carcinoma (HP:0002671) | 2.26330953 |
33 | Heterotopia (HP:0002282) | 2.25669578 |
34 | Upper limb amyotrophy (HP:0009129) | 2.23297352 |
35 | Distal upper limb amyotrophy (HP:0007149) | 2.23297352 |
36 | Proximal placement of thumb (HP:0009623) | 2.22692294 |
37 | Pointed chin (HP:0000307) | 2.21781340 |
38 | Abnormality of the distal phalanx of the thumb (HP:0009617) | 2.20675873 |
39 | Trismus (HP:0000211) | 2.19525085 |
40 | Genu recurvatum (HP:0002816) | 2.19180862 |
41 | Abnormality of the lower motor neuron (HP:0002366) | 2.16952001 |
42 | Bowel diverticulosis (HP:0005222) | 2.16403967 |
43 | Centrally nucleated skeletal muscle fibers (HP:0003687) | 2.15598672 |
44 | Progressive muscle weakness (HP:0003323) | 2.15183473 |
45 | Dysmetric saccades (HP:0000641) | 2.14131142 |
46 | Hand muscle atrophy (HP:0009130) | 2.13343606 |
47 | Macroorchidism (HP:0000053) | 2.13221062 |
48 | Mitral valve prolapse (HP:0001634) | 2.12529545 |
49 | Gastrointestinal carcinoma (HP:0002672) | 2.10744632 |
50 | Malignant gastrointestinal tract tumors (HP:0006749) | 2.10744632 |
51 | Abnormality of the fingertips (HP:0001211) | 2.05727179 |
52 | High pitched voice (HP:0001620) | 2.04864119 |
53 | Fragile skin (HP:0001030) | 2.04269168 |
54 | Broad distal phalanx of finger (HP:0009836) | 2.03980081 |
55 | Urethral obstruction (HP:0000796) | 2.03029289 |
56 | Subacute progressive viral hepatitis (HP:0006572) | 2.02877556 |
57 | Skin tags (HP:0010609) | 2.01082631 |
58 | Cellulitis (HP:0100658) | 2.00243289 |
59 | Bladder diverticulum (HP:0000015) | 2.00205237 |
60 | Patellar dislocation (HP:0002999) | 1.99356204 |
61 | Broad thumb (HP:0011304) | 1.97103732 |
62 | Sparse lateral eyebrow (HP:0005338) | 1.96987171 |
63 | Fibroma (HP:0010614) | 1.96792304 |
64 | Deep palmar crease (HP:0006191) | 1.96524182 |
65 | Abnormality of oral frenula (HP:0000190) | 1.96132808 |
66 | Glioma (HP:0009733) | 1.96064657 |
67 | Spinal cord lesions (HP:0100561) | 1.95625697 |
68 | Syringomyelia (HP:0003396) | 1.95625697 |
69 | Ankle contracture (HP:0006466) | 1.94974538 |
70 | Rectal prolapse (HP:0002035) | 1.94958246 |
71 | Ankyloglossia (HP:0010296) | 1.94869478 |
72 | Missing ribs (HP:0000921) | 1.94248210 |
73 | Fibrous tissue neoplasm (HP:0012316) | 1.93362196 |
74 | Medulloblastoma (HP:0002885) | 1.93269394 |
75 | Lower limb amyotrophy (HP:0007210) | 1.91844682 |
76 | Neoplasm of striated muscle (HP:0009728) | 1.90967380 |
77 | Hallux valgus (HP:0001822) | 1.90777656 |
78 | Deviation of the hallux (HP:0010051) | 1.89908797 |
79 | Back pain (HP:0003418) | 1.88326340 |
80 | Neoplasm of the oral cavity (HP:0100649) | 1.88227461 |
81 | Abnormality of the thoracic spine (HP:0100711) | 1.88107544 |
82 | Biconcave vertebral bodies (HP:0004586) | 1.86974272 |
83 | Abnormality of the distal phalanges of the toes (HP:0010182) | 1.86949869 |
84 | Mitral regurgitation (HP:0001653) | 1.86260239 |
85 | Aneurysm (HP:0002617) | 1.84416657 |
86 | Long eyelashes (HP:0000527) | 1.84036114 |
87 | Bowing of the arm (HP:0006488) | 1.83590058 |
88 | Bowed forearm bones (HP:0003956) | 1.83590058 |
89 | Adenoma sebaceum (HP:0009720) | 1.82171861 |
90 | Angiofibromas (HP:0010615) | 1.82171861 |
91 | Broad palm (HP:0001169) | 1.81491098 |
92 | Flat cornea (HP:0007720) | 1.80108754 |
93 | Hereditary nonpolyposis colorectal carcinoma (HP:0006716) | 1.79871489 |
94 | Spastic diplegia (HP:0001264) | 1.79592497 |
95 | Abnormal gallbladder physiology (HP:0012438) | 1.79272685 |
96 | Cholecystitis (HP:0001082) | 1.79272685 |
97 | Distal lower limb muscle weakness (HP:0009053) | 1.77745376 |
98 | Dislocated radial head (HP:0003083) | 1.77510893 |
99 | Enlarged penis (HP:0000040) | 1.77434602 |
100 | Radial bowing (HP:0002986) | 1.77015291 |
101 | Trigonocephaly (HP:0000243) | 1.76545547 |
102 | Hyperparathyroidism (HP:0000843) | 1.76095905 |
103 | Preauricular skin tag (HP:0000384) | 1.75415344 |
104 | Achilles tendon contracture (HP:0001771) | 1.75355024 |
105 | Dilatation of the ascending aorta (HP:0005111) | 1.75140916 |
106 | Reticulocytosis (HP:0001923) | 1.73882632 |
107 | Progressive external ophthalmoplegia (HP:0000590) | 1.73650183 |
108 | Turricephaly (HP:0000262) | 1.73365245 |
109 | Skull defect (HP:0001362) | 1.72733150 |
110 | Arnold-Chiari malformation (HP:0002308) | 1.72555928 |
111 | Polygenic inheritance (HP:0010982) | 1.72463493 |
112 | Abnormality of the diencephalon (HP:0010662) | 1.71984909 |
113 | Advanced eruption of teeth (HP:0006288) | 1.71275488 |
114 | Volvulus (HP:0002580) | 1.71058502 |
115 | Abnormality of the calcaneus (HP:0008364) | 1.70778978 |
116 | Bicuspid aortic valve (HP:0001647) | 1.70563402 |
117 | Lymphangioma (HP:0100764) | 1.70226128 |
118 | Blue sclerae (HP:0000592) | 1.69975864 |
119 | Premature skin wrinkling (HP:0100678) | 1.69025659 |
120 | Osteolytic defects of the phalanges of the hand (HP:0009771) | 1.68914737 |
121 | Osteolytic defects of the hand bones (HP:0009699) | 1.68914737 |
122 | Short nail (HP:0001799) | 1.68458930 |
123 | Abnormality of the peritoneum (HP:0002585) | 1.68116206 |
124 | Persistence of primary teeth (HP:0006335) | 1.67728915 |
125 | Annular pancreas (HP:0001734) | 1.67064241 |
126 | Difficulty climbing stairs (HP:0003551) | 1.66902400 |
127 | Prominent nose (HP:0000448) | 1.65712542 |
128 | Rhabdomyosarcoma (HP:0002859) | 1.65628339 |
129 | Vertebral arch anomaly (HP:0008438) | 1.65407717 |
130 | Sandal gap (HP:0001852) | 1.65345465 |
131 | Thin ribs (HP:0000883) | 1.64503184 |
132 | Aortic aneurysm (HP:0004942) | 1.64359517 |
133 | Abnormality of the radial head (HP:0003995) | 1.64327756 |
134 | Metaphyseal cupping (HP:0003021) | 1.64262491 |
135 | Rib fusion (HP:0000902) | 1.64020016 |
136 | Hemorrhage of the eye (HP:0011885) | 1.63743864 |
137 | Abnormality of the phalanges of the hallux (HP:0010057) | 1.62789329 |
138 | Disproportionate tall stature (HP:0001519) | 1.62554591 |
139 | Biliary tract neoplasm (HP:0100574) | 1.62220330 |
140 | Colon cancer (HP:0003003) | 1.61365333 |
141 | Insidious onset (HP:0003587) | 1.60910213 |
142 | Termporal pattern (HP:0011008) | 1.60910213 |
143 | Obsessive-compulsive behavior (HP:0000722) | 1.60601262 |
144 | Segmental peripheral demyelination/remyelination (HP:0003481) | 1.59733387 |
145 | Leiomyosarcoma (HP:0100243) | 1.59159009 |
146 | Uterine leiomyosarcoma (HP:0002891) | 1.59159009 |
147 | Short phalanx of the thumb (HP:0009660) | 1.58777881 |
148 | Broad phalanges of the hand (HP:0009768) | 1.58229497 |
149 | Supernumerary ribs (HP:0005815) | 1.58108200 |
150 | Large earlobe (HP:0009748) | 1.57621167 |
151 | Abnormal number of incisors (HP:0011064) | 1.57579532 |
152 | Thin bony cortex (HP:0002753) | 1.57389061 |
153 | Spina bifida occulta (HP:0003298) | 1.57296298 |
154 | Hypopigmentation of the fundus (HP:0007894) | 1.57199556 |
155 | Increased variability in muscle fiber diameter (HP:0003557) | 1.56660287 |
156 | Elbow flexion contracture (HP:0002987) | 1.56165086 |
157 | Abnormal ossification of hand bones (HP:0005921) | 1.55831023 |
158 | Spinal cord compression (HP:0002176) | 1.55240763 |
159 | Germ cell neoplasia (HP:0100728) | 1.54621637 |
160 | Spinal rigidity (HP:0003306) | 1.54380019 |
161 | High anterior hairline (HP:0009890) | 1.54099174 |
162 | Septate vagina (HP:0001153) | 1.52220206 |
163 | Natal tooth (HP:0000695) | 1.51712396 |
164 | Micronodular cirrhosis (HP:0001413) | 1.51221436 |
165 | Generalized amyotrophy (HP:0003700) | 1.51018544 |
166 | Stridor (HP:0010307) | 1.50930272 |
167 | Abnormality of skeletal muscle fiber size (HP:0012084) | 1.50561745 |
168 | Bowel incontinence (HP:0002607) | 1.49933821 |
Rank | Gene Set | Z-score |
---|---|---|
1 | EEF2K | 4.63161907 |
2 | SMG1 | 4.31676441 |
3 | TRIB3 | 4.27759008 |
4 | CDK12 | 3.87682673 |
5 | PKN2 | 3.82146421 |
6 | MAP3K10 | 3.79806744 |
7 | PRPF4B | 3.31323659 |
8 | IRAK3 | 2.76203504 |
9 | CDC7 | 2.31194601 |
10 | NEK2 | 2.06300129 |
11 | NME2 | 2.01359169 |
12 | ALK | 1.98383980 |
13 | TTN | 1.93296425 |
14 | ICK | 1.92773295 |
15 | PTK6 | 1.85867740 |
16 | RPS6KB2 | 1.85234639 |
17 | PDGFRA | 1.63271664 |
18 | STK10 | 1.61803676 |
19 | RIPK1 | 1.59292914 |
20 | MAP4K1 | 1.55190445 |
21 | BMX | 1.52504768 |
22 | LRRK2 | 1.51743106 |
23 | ERN1 | 1.44169093 |
24 | PAK4 | 1.39239338 |
25 | MTOR | 1.38636431 |
26 | CDK4 | 1.38521428 |
27 | PASK | 1.34324529 |
28 | SCYL2 | 1.33623049 |
29 | TYRO3 | 1.30929485 |
30 | SIK2 | 1.30430677 |
31 | GRK6 | 1.28646249 |
32 | MAP3K13 | 1.27536379 |
33 | NEK1 | 1.25359935 |
34 | CDK6 | 1.23234733 |
35 | MAP3K8 | 1.21348669 |
36 | BRD4 | 1.19486803 |
37 | SIK1 | 1.18323854 |
38 | TAOK2 | 1.16261862 |
39 | MST1R | 1.13525590 |
40 | PAK2 | 1.11021236 |
41 | TTK | 1.06162920 |
42 | LATS1 | 1.04820899 |
43 | TSSK6 | 1.02762044 |
44 | CDK7 | 0.95973102 |
45 | EPHA2 | 0.93361105 |
46 | CAMK1D | 0.92591435 |
47 | TESK2 | 0.91311295 |
48 | CHEK1 | 0.90518920 |
49 | TAOK1 | 0.85281559 |
50 | CAMK1G | 0.84733059 |
51 | LATS2 | 0.84554397 |
52 | ARAF | 0.84304815 |
53 | IRAK4 | 0.83083910 |
54 | IRAK2 | 0.81068568 |
55 | KSR2 | 0.79385083 |
56 | DDR2 | 0.78468360 |
57 | TGFBR1 | 0.77288431 |
58 | MAP2K2 | 0.76870791 |
59 | STK3 | 0.75049334 |
60 | FGFR1 | 0.74682911 |
61 | PDGFRB | 0.74535889 |
62 | MAP3K9 | 0.73329053 |
63 | ATR | 0.73120412 |
64 | MAP3K14 | 0.72264477 |
65 | SIK3 | 0.70837337 |
66 | RPS6KA4 | 0.70525602 |
67 | MARK2 | 0.69707404 |
68 | CDK2 | 0.69705474 |
69 | MAP3K1 | 0.68445943 |
70 | STK4 | 0.68329596 |
71 | BRAF | 0.67854260 |
72 | FLT3 | 0.67615953 |
73 | ILK | 0.67393199 |
74 | DMPK | 0.66629332 |
75 | RIPK4 | 0.66260742 |
76 | PRKD2 | 0.65547241 |
77 | LMTK2 | 0.64110278 |
78 | PDPK1 | 0.64097936 |
79 | PRKD3 | 0.63779672 |
80 | FGFR4 | 0.62707533 |
81 | TESK1 | 0.62403691 |
82 | PTK2 | 0.62147797 |
83 | PIM1 | 0.62129052 |
84 | RPS6KA2 | 0.60391832 |
85 | AURKB | 0.59273373 |
86 | RET | 0.58579581 |
87 | MAP3K7 | 0.56684880 |
88 | AKT2 | 0.56282531 |
89 | EPHB1 | 0.55933724 |
90 | MAP3K3 | 0.55131845 |
91 | NTRK1 | 0.54479554 |
92 | MAP3K11 | 0.53415408 |
93 | VRK2 | 0.53340201 |
94 | AURKA | 0.53294268 |
95 | MAP2K3 | 0.52884459 |
96 | PLK1 | 0.51109073 |
97 | RPS6KA1 | 0.51065393 |
98 | ATM | 0.51058288 |
99 | CSK | 0.50876301 |
100 | FGFR3 | 0.49110590 |
101 | WEE1 | 0.48481830 |
102 | CDK8 | 0.48285137 |
103 | CSF1R | 0.47996394 |
104 | CSNK1D | 0.47739907 |
105 | HCK | 0.46264987 |
106 | CDK9 | 0.45830789 |
107 | MKNK1 | 0.45523634 |
108 | ZAP70 | 0.45514887 |
109 | CHEK2 | 0.45208869 |
110 | PAK6 | 0.44249745 |
111 | DYRK1B | 0.44155443 |
112 | BUB1 | 0.43538601 |
113 | CSNK1E | 0.43419192 |
114 | MELK | 0.41441237 |
115 | CLK1 | 0.40971320 |
116 | PRKCH | 0.40654614 |
117 | * CDK1 | 0.40505157 |
118 | BTK | 0.39527118 |
119 | PRKDC | 0.39026380 |
120 | PAK1 | 0.38821168 |
121 | MAPK11 | 0.38752116 |
122 | MAPKAPK3 | 0.38553207 |
123 | TBK1 | 0.37280094 |
124 | MAPK14 | 0.37269947 |
125 | ITK | 0.37064343 |
126 | HIPK2 | 0.36910251 |
127 | JAK3 | 0.35554234 |
128 | RPS6KC1 | 0.35497668 |
129 | RPS6KL1 | 0.35497668 |
130 | CDC42BPA | 0.34779830 |
131 | BRSK1 | 0.34039354 |
132 | MET | 0.33274721 |
133 | RPS6KA6 | 0.32412515 |
134 | PRKG2 | 0.31532733 |
135 | MOS | 0.30974735 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 2.21361145 |
2 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 2.13880520 |
3 | One carbon pool by folate_Homo sapiens_hsa00670 | 2.08277779 |
4 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 2.00334966 |
5 | DNA replication_Homo sapiens_hsa03030 | 1.95074037 |
6 | * Spliceosome_Homo sapiens_hsa03040 | 1.94325534 |
7 | RNA transport_Homo sapiens_hsa03013 | 1.93379412 |
8 | mTOR signaling pathway_Homo sapiens_hsa04150 | 1.75325802 |
9 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 1.74461113 |
10 | Notch signaling pathway_Homo sapiens_hsa04330 | 1.68164602 |
11 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 1.66285264 |
12 | Cell cycle_Homo sapiens_hsa04110 | 1.65916490 |
13 | Other glycan degradation_Homo sapiens_hsa00511 | 1.62207821 |
14 | Mismatch repair_Homo sapiens_hsa03430 | 1.61029459 |
15 | Small cell lung cancer_Homo sapiens_hsa05222 | 1.55530044 |
16 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 1.54067554 |
17 | Lysine degradation_Homo sapiens_hsa00310 | 1.53812544 |
18 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 1.48810021 |
19 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 1.47543254 |
20 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.46602445 |
21 | Viral carcinogenesis_Homo sapiens_hsa05203 | 1.46108315 |
22 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 1.45153064 |
23 | Colorectal cancer_Homo sapiens_hsa05210 | 1.44456329 |
24 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 1.41985753 |
25 | Prion diseases_Homo sapiens_hsa05020 | 1.40512019 |
26 | Adherens junction_Homo sapiens_hsa04520 | 1.37661579 |
27 | Bladder cancer_Homo sapiens_hsa05219 | 1.36425426 |
28 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 1.36149067 |
29 | Endometrial cancer_Homo sapiens_hsa05213 | 1.35635557 |
30 | Basal cell carcinoma_Homo sapiens_hsa05217 | 1.34868393 |
31 | HTLV-I infection_Homo sapiens_hsa05166 | 1.34467634 |
32 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 1.34311040 |
33 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.33688142 |
34 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 1.32476127 |
35 | Hippo signaling pathway_Homo sapiens_hsa04390 | 1.29765038 |
36 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 1.29295805 |
37 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 1.21269519 |
38 | Pancreatic cancer_Homo sapiens_hsa05212 | 1.20952477 |
39 | Glioma_Homo sapiens_hsa05214 | 1.19704509 |
40 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 1.19365630 |
41 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 1.18490617 |
42 | VEGF signaling pathway_Homo sapiens_hsa04370 | 1.17984371 |
43 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 1.17636295 |
44 | Base excision repair_Homo sapiens_hsa03410 | 1.17066930 |
45 | Viral myocarditis_Homo sapiens_hsa05416 | 1.15541669 |
46 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 1.12895019 |
47 | Focal adhesion_Homo sapiens_hsa04510 | 1.12688735 |
48 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 1.12125416 |
49 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.10031935 |
50 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 1.07728584 |
51 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 1.06641644 |
52 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 1.06055698 |
53 | Thyroid cancer_Homo sapiens_hsa05216 | 1.05352656 |
54 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 1.04330896 |
55 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 1.04139975 |
56 | Renal cell carcinoma_Homo sapiens_hsa05211 | 1.03038709 |
57 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.99370435 |
58 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.98206535 |
59 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.97752295 |
60 | Galactose metabolism_Homo sapiens_hsa00052 | 0.93861225 |
61 | Apoptosis_Homo sapiens_hsa04210 | 0.89540406 |
62 | Hepatitis B_Homo sapiens_hsa05161 | 0.89265620 |
63 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.87946008 |
64 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.87791131 |
65 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.87780010 |
66 | Hepatitis C_Homo sapiens_hsa05160 | 0.86780496 |
67 | Prostate cancer_Homo sapiens_hsa05215 | 0.86563592 |
68 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.85331225 |
69 | Insulin resistance_Homo sapiens_hsa04931 | 0.82654168 |
70 | Influenza A_Homo sapiens_hsa05164 | 0.82226677 |
71 | Pathways in cancer_Homo sapiens_hsa05200 | 0.82121716 |
72 | Sulfur relay system_Homo sapiens_hsa04122 | 0.81510537 |
73 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.80959866 |
74 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.80917360 |
75 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 0.80325776 |
76 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.79844044 |
77 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.79673782 |
78 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.78979649 |
79 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.78970485 |
80 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.78480324 |
81 | Tight junction_Homo sapiens_hsa04530 | 0.77880321 |
82 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.77605219 |
83 | Osteoclast differentiation_Homo sapiens_hsa04380 | 0.76611413 |
84 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.76555808 |
85 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.76183687 |
86 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.76121784 |
87 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.74866567 |
88 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.73980266 |
89 | Carbon metabolism_Homo sapiens_hsa01200 | 0.73706969 |
90 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.73585669 |
91 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.73395143 |
92 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.73121960 |
93 | Shigellosis_Homo sapiens_hsa05131 | 0.71653534 |
94 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.70828745 |
95 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.70390438 |
96 | Platelet activation_Homo sapiens_hsa04611 | 0.70336876 |
97 | Amoebiasis_Homo sapiens_hsa05146 | 0.70064729 |
98 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.70027056 |
99 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.68125608 |
100 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.66847342 |
101 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.64925392 |
102 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.64479200 |
103 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.63494774 |
104 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.63479677 |
105 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.63160713 |
106 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.62758126 |
107 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.62165575 |
108 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.61645701 |
109 | Endocytosis_Homo sapiens_hsa04144 | 0.59363971 |
110 | ECM-receptor interaction_Homo sapiens_hsa04512 | 0.58759907 |
111 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.58407297 |
112 | Alcoholism_Homo sapiens_hsa05034 | 0.57780541 |
113 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.57632163 |
114 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.56243206 |
115 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.55820672 |
116 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.55678714 |
117 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.54840399 |
118 | Leishmaniasis_Homo sapiens_hsa05140 | 0.54017554 |
119 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 0.53232236 |
120 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.52491160 |
121 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.52387707 |
122 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.51962538 |
123 | Salmonella infection_Homo sapiens_hsa05132 | 0.51624945 |
124 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.51470237 |
125 | Measles_Homo sapiens_hsa05162 | 0.51197602 |
126 | RNA degradation_Homo sapiens_hsa03018 | 0.51113457 |
127 | Melanoma_Homo sapiens_hsa05218 | 0.49290531 |
128 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.48670909 |
129 | Long-term potentiation_Homo sapiens_hsa04720 | 0.47313548 |