UACA

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1plasma membrane repair (GO:0001778)5.75834937
2actin-myosin filament sliding (GO:0033275)5.10997285
3muscle filament sliding (GO:0030049)5.10997285
4glomerular visceral epithelial cell development (GO:0072015)4.96607003
5sarcomere organization (GO:0045214)4.93624393
6glomerular basement membrane development (GO:0032836)4.71542460
7vascular endothelial growth factor signaling pathway (GO:0038084)4.54495292
8actin-mediated cell contraction (GO:0070252)4.51946749
9regulation of skeletal muscle contraction (GO:0014819)4.46754856
10bundle of His cell to Purkinje myocyte communication (GO:0086069)4.46404448
11cardiac myofibril assembly (GO:0055003)4.40526926
12glomerular epithelial cell development (GO:0072310)4.32231282
13myofibril assembly (GO:0030239)4.20690350
14chondrocyte proliferation (GO:0035988)3.99148235
15negative regulation of potassium ion transmembrane transporter activity (GO:1901017)3.81158522
16actin filament-based movement (GO:0030048)3.75590585
17kidney mesenchyme development (GO:0072074)3.74216905
18actomyosin structure organization (GO:0031032)3.69820646
19cell migration involved in sprouting angiogenesis (GO:0002042)3.68677860
20carnitine shuttle (GO:0006853)3.59124998
21endodermal cell differentiation (GO:0035987)3.52909244
22negative regulation of potassium ion transmembrane transport (GO:1901380)3.52404472
23retina vasculature morphogenesis in camera-type eye (GO:0061299)3.52404050
24lymph vessel development (GO:0001945)3.51116843
25regulation of p38MAPK cascade (GO:1900744)3.48791769
26heart trabecula formation (GO:0060347)3.48094223
27epithelial cell-cell adhesion (GO:0090136)3.45931990
28cellular response to vascular endothelial growth factor stimulus (GO:0035924)3.43117647
29metanephric mesenchyme development (GO:0072075)3.41868960
30sequestering of extracellular ligand from receptor (GO:0035581)3.41226419
31cardiac muscle cell development (GO:0055013)3.26899049
32basement membrane organization (GO:0071711)3.26775493
33positive regulation of p38MAPK cascade (GO:1900745)3.25129758
34pericardium development (GO:0060039)3.24586997
35renal filtration (GO:0097205)3.23127586
36Golgi transport vesicle coating (GO:0048200)3.22859866
37COPI coating of Golgi vesicle (GO:0048205)3.22859866
38coronary vasculature morphogenesis (GO:0060977)3.22307101
39negative regulation of chondrocyte differentiation (GO:0032331)3.17558616
40endocardial cushion development (GO:0003197)3.16999024
41substrate adhesion-dependent cell spreading (GO:0034446)3.15628748
42cardiac cell development (GO:0055006)3.15184442
43blood vessel endothelial cell migration (GO:0043534)3.10018772
44fatty acid transmembrane transport (GO:1902001)3.09017399
45regulation of transforming growth factor beta2 production (GO:0032909)3.08493450
46positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316)3.08363018
47skeletal muscle adaptation (GO:0043501)3.06084393
48vascular endothelial growth factor receptor signaling pathway (GO:0048010)3.04655421
49hemidesmosome assembly (GO:0031581)3.04082378
50sarcoplasmic reticulum calcium ion transport (GO:0070296)3.03037389
51substrate-dependent cell migration (GO:0006929)3.02394763
52muscle cell migration (GO:0014812)3.00994002
53lymphangiogenesis (GO:0001946)3.00462652
54notochord development (GO:0030903)3.00350309
55paraxial mesoderm development (GO:0048339)2.99941843
56hippo signaling (GO:0035329)2.99714777
57skin morphogenesis (GO:0043589)2.99180723
58atrioventricular valve morphogenesis (GO:0003181)2.98464762
59venous blood vessel morphogenesis (GO:0048845)2.95175547
60tricarboxylic acid cycle (GO:0006099)2.91623681
61cardiac muscle contraction (GO:0060048)2.89314452
62bone trabecula formation (GO:0060346)2.88855754
63ventricular cardiac muscle cell development (GO:0055015)2.86700925
64cell-substrate junction assembly (GO:0007044)2.86656664
65endothelial cell morphogenesis (GO:0001886)2.85660237
66protein heterotrimerization (GO:0070208)2.84946948
67regulation of integrin-mediated signaling pathway (GO:2001044)2.83434906
68skeletal muscle contraction (GO:0003009)2.83011057
69cardiac muscle tissue morphogenesis (GO:0055008)2.82447899
70ventricular cardiac muscle cell action potential (GO:0086005)2.81875786
71mesenchymal-epithelial cell signaling (GO:0060638)2.81711426
72carnitine transmembrane transport (GO:1902603)2.78526534
73regulation of calcineurin-NFAT signaling cascade (GO:0070884)2.78056120
74adherens junction assembly (GO:0034333)2.77924696
75anterior/posterior axis specification, embryo (GO:0008595)2.77280834
76glomerular filtration (GO:0003094)2.76997210
77striated muscle contraction (GO:0006941)2.76664200
78negative regulation of protein localization to cell surface (GO:2000009)2.75148384
79negative regulation of axon extension involved in axon guidance (GO:0048843)2.74465228
80positive regulation of osteoblast proliferation (GO:0033690)2.73090631
81mesodermal cell differentiation (GO:0048333)2.72871155
82regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (GO:0010880)2.71114057
83muscle tissue morphogenesis (GO:0060415)2.70671881
84patterning of blood vessels (GO:0001569)2.69797345
85protein hydroxylation (GO:0018126)2.69458609
86regulation of cardioblast differentiation (GO:0051890)2.68156483
87carnitine transport (GO:0015879)2.67679853
88amino-acid betaine transport (GO:0015838)2.67679853
89polarized epithelial cell differentiation (GO:0030859)2.66973732
90desmosome organization (GO:0002934)2.66408678
91glomerulus development (GO:0032835)2.66293271
924-hydroxyproline metabolic process (GO:0019471)2.66151069
93wound healing, spreading of epidermal cells (GO:0035313)2.65953146
94smooth muscle tissue development (GO:0048745)2.65208095
95regulation of metanephric nephron tubule epithelial cell differentiation (GO:0072307)2.65072632
96regulation of branching involved in salivary gland morphogenesis (GO:0060693)2.64853468
97negative regulation of cell size (GO:0045792)2.63629449
98endoderm development (GO:0007492)2.62937913
99branching involved in salivary gland morphogenesis (GO:0060445)2.62727103
100embryonic foregut morphogenesis (GO:0048617)2.61709359
101trabecula formation (GO:0060343)2.60180386
102ventricular cardiac muscle tissue morphogenesis (GO:0055010)2.59777940
103cardiac muscle cell proliferation (GO:0060038)2.59386547
104insulin-like growth factor receptor signaling pathway (GO:0048009)2.57467101
105negative regulation of cardiac muscle tissue growth (GO:0055022)2.57279184
106negative regulation of heart growth (GO:0061117)2.57279184
107regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547)2.57237731
108activation of signaling protein activity involved in unfolded protein response (GO:0006987)2.57149616
109ventricular septum development (GO:0003281)2.56885153
110collagen metabolic process (GO:0032963)2.56772394
111stress fiber assembly (GO:0043149)2.55970734
112focal adhesion assembly (GO:0048041)2.55244177
113cell-substrate adherens junction assembly (GO:0007045)2.55244177
114regulation of Wnt signaling pathway, planar cell polarity pathway (GO:2000095)2.54770446
115regulation of tight junction assembly (GO:2000810)2.53466331
116negative regulation of cartilage development (GO:0061037)2.53407537
117regulation of actin filament-based movement (GO:1903115)2.51975308
118positive regulation of Rho protein signal transduction (GO:0035025)2.51893012
119regulation of axon extension involved in axon guidance (GO:0048841)2.51887257
120extracellular fibril organization (GO:0043206)2.51561119
121lung vasculature development (GO:0060426)2.51517328
122cell adhesion mediated by integrin (GO:0033627)2.51007837
123endocardial cushion morphogenesis (GO:0003203)2.49450762
124muscle contraction (GO:0006936)2.48507438
125endothelial cell chemotaxis (GO:0035767)2.47803585
126positive regulation of endothelial cell apoptotic process (GO:2000353)2.46739611
127collagen catabolic process (GO:0030574)2.46190244
128regulation of vascular endothelial growth factor signaling pathway (GO:1900746)2.46136522
129embryonic heart tube development (GO:0035050)2.45693699
130regulation of SMAD protein import into nucleus (GO:0060390)2.44960181
131positive regulation of nuclease activity (GO:0032075)2.44409896
132positive regulation of glycogen biosynthetic process (GO:0045725)2.43586517
133neuron projection extension involved in neuron projection guidance (GO:1902284)2.43229034
134axon extension involved in axon guidance (GO:0048846)2.43229034
135dermatan sulfate biosynthetic process (GO:0030208)2.42907818
136peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan (GO:0019800)2.42709293
137heart valve morphogenesis (GO:0003179)2.41691736
138multicellular organismal macromolecule metabolic process (GO:0044259)2.40377922
139regulation of chondrocyte differentiation (GO:0032330)2.40369371
140cell migration involved in heart development (GO:0060973)2.40254646
141endothelial cell migration (GO:0043542)2.40080505
142cellular response to vitamin (GO:0071295)2.39213867
143cardiac epithelial to mesenchymal transition (GO:0060317)2.39010071
144positive regulation of histone deacetylation (GO:0031065)2.38333715
145exocrine pancreas development (GO:0031017)2.38109840
146peptidyl-proline hydroxylation (GO:0019511)2.36701260
147positive regulation of cartilage development (GO:0061036)2.36666999
148growth hormone secretion (GO:0030252)2.36477528
149cartilage development involved in endochondral bone morphogenesis (GO:0060351)2.36340432
150gap junction assembly (GO:0016264)2.35962282
151negative regulation of cardiac muscle cell apoptotic process (GO:0010667)2.35861297
152regulation of heart morphogenesis (GO:2000826)2.34948235
153collagen fibril organization (GO:0030199)2.34396950
154neural crest cell development (GO:0014032)2.34170337
155myoblast fusion (GO:0007520)2.33979414
156regulation of cartilage development (GO:0061035)2.33217954
157multicellular organismal metabolic process (GO:0044236)2.32919841
158response to muscle activity (GO:0014850)2.32913345
159mesenchyme morphogenesis (GO:0072132)2.32882476
160positive regulation of catenin import into nucleus (GO:0035413)2.32714805
161chondrocyte development (GO:0002063)2.32461321
162extracellular matrix assembly (GO:0085029)2.32118625
163positive regulation of cardiac muscle tissue development (GO:0055025)2.32088029
164positive regulation of epithelial to mesenchymal transition (GO:0010718)2.31912481
165negative chemotaxis (GO:0050919)2.31565830
166multicellular organismal catabolic process (GO:0044243)2.30993230
167positive regulation of cardiac muscle cell proliferation (GO:0060045)2.30810330
168dermatan sulfate metabolic process (GO:0030205)2.29962707
169protein localization to cell surface (GO:0034394)2.29810816

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TP63_17297297_ChIP-ChIP_HaCaT_Human4.93151970
2TRIM28_21343339_ChIP-Seq_HEK293_Human3.76640150
3PPARG_19300518_ChIP-PET_3T3-L1_Mouse3.51404269
4CLOCK_20551151_ChIP-Seq_293T_Human3.47501468
5RARG_19884340_ChIP-ChIP_MEFs_Mouse3.41769533
6NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.98075311
7ZNF263_19887448_ChIP-Seq_K562_Human2.88069208
8ESR1_21235772_ChIP-Seq_MCF-7_Human2.82275540
9PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse2.79008772
10STAT6_21828071_ChIP-Seq_BEAS2B_Human2.55801055
11EP300_21415370_ChIP-Seq_HL-1_Mouse2.55572541
12CEBPD_23245923_ChIP-Seq_MEFs_Mouse2.55021349
13SMAD_19615063_ChIP-ChIP_OVARY_Human2.49450699
14TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse2.45458565
15ESR2_21235772_ChIP-Seq_MCF-7_Human2.37176763
16* TBX20_22328084_ChIP-Seq_HEART_Mouse2.34133845
17* TBX20_22080862_ChIP-Seq_HEART_Mouse2.34133845
18HIF1A_21447827_ChIP-Seq_MCF-7_Human2.33927162
19CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse2.30166941
20TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human2.27823806
21NRF2_20460467_ChIP-Seq_MEFs_Mouse2.10844529
22NFE2L2_20460467_ChIP-Seq_MEFs_Mouse2.10844529
23TP53_16413492_ChIP-PET_HCT116_Human2.07330760
24* KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human2.05667117
25ZIC3_20872845_ChIP-ChIP_MESCs_Mouse2.03467884
26FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.02532383
27* ZNF217_24962896_ChIP-Seq_MCF-7_Human2.01394723
28EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.99413953
29ESR1_20079471_ChIP-ChIP_T-47D_Human1.95948018
30RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.94888246
31RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.90753219
32ELK3_25401928_ChIP-Seq_HUVEC_Human1.83807316
33TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.79655928
34RBPJ_22232070_ChIP-Seq_NCS_Mouse1.79648825
35TP53_18474530_ChIP-ChIP_U2OS_Human1.79173768
36MEF2A_21415370_ChIP-Seq_HL-1_Mouse1.73342096
37GBX2_23144817_ChIP-Seq_PC3_Human1.72412700
38TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.71966801
39* PPAR_26484153_Chip-Seq_NCI-H1993_Human1.70505696
40SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.69387955
41ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.68609929
42NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.66565188
43PIAS1_25552417_ChIP-Seq_VCAP_Human1.66278307
44ATF3_27146783_Chip-Seq_COLON_Human1.65823259
45RACK7_27058665_Chip-Seq_MCF-7_Human1.65297657
46SALL1_21062744_ChIP-ChIP_HESCs_Human1.64099785
47EGR1_19374776_ChIP-ChIP_THP-1_Human1.56922929
48* SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.56570237
49GATA2_21666600_ChIP-Seq_HMVEC_Human1.53496954
50NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.53485212
51* KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.52251453
52GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.52183567
53P300_27058665_Chip-Seq_ZR-75-30cells_Human1.50765931
54WT1_19549856_ChIP-ChIP_CCG9911_Human1.49640391
55* FOXO3_23340844_ChIP-Seq_DLD1_Human1.49343152
56* PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.49307822
57WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.48066275
58* AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.47764428
59FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human1.45751041
60SOX2_27498859_Chip-Seq_STOMACH_Mouse1.45446899
61ZFP57_27257070_Chip-Seq_ESCs_Mouse1.43332411
62BP1_19119308_ChIP-ChIP_Hs578T_Human1.42956699
63STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.42951480
64* FOXM1_26456572_ChIP-Seq_MCF-7_Human1.40019509
65CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.39934403
66CJUN_26792858_Chip-Seq_BT549_Human1.39791357
67SOX9_24532713_ChIP-Seq_HFSC_Mouse1.38928473
68SALL4_18804426_ChIP-ChIP_XEN_Mouse1.37799356
69NFIB_24661679_ChIP-Seq_LUNG_Mouse1.37578521
70* RUNX1_27514584_Chip-Seq_MCF-7_Human1.34588631
71PPARA_22158963_ChIP-Seq_LIVER_Mouse1.34084461
72NKX2-5_21415370_ChIP-Seq_HL-1_Mouse1.33410652
73KDM2B_26808549_Chip-Seq_SUP-B15_Human1.32818222
74GATA6_25053715_ChIP-Seq_YYC3_Human1.32395343
75* SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.32282954
76ZFP281_18757296_ChIP-ChIP_E14_Mouse1.32009990
77* BRD4_25478319_ChIP-Seq_HGPS_Human1.31928427
78ISL1_27105846_Chip-Seq_CPCs_Mouse1.31481173
79TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.31283868
80LXR_22158963_ChIP-Seq_LIVER_Mouse1.31274321
81UBF1/2_26484160_Chip-Seq_HMECs_Human1.30332670
82PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.29658415
83ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.27329859
84KDM2B_26808549_Chip-Seq_DND41_Human1.27320450
85ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.26758777
86* SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.26644359
87* SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.26644359
88* TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.25858238
89DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.25105153
90CTNNB1_20460455_ChIP-Seq_HCT116_Human1.24974367
91CDX2_19796622_ChIP-Seq_MESCs_Mouse1.24791354
92CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.24190892
93SMAD4_21799915_ChIP-Seq_A2780_Human1.22773145
94TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.21671752
95ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.20361447
96STAT3_1855785_ChIP-Seq_MESCs_Mouse1.20182066
97KDM2B_26808549_Chip-Seq_K562_Human1.19599587
98KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.19399730
99KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.19399730
100KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.19399730
101CDX2_20551321_ChIP-Seq_CACO-2_Human1.19250995
102TCF3_18692474_ChIP-Seq_MEFs_Mouse1.16163096
103SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.15943033
104OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.15702021
105EED_16625203_ChIP-ChIP_MESCs_Mouse1.14580584
106* GATA4_25053715_ChIP-Seq_YYC3_Human1.14504536
107AR_21909140_ChIP-Seq_LNCAP_Human1.14346554
108JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.13689942
109SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.12761093
110TBX3_20139965_ChIP-Seq_ESCs_Mouse1.12381037
111POU3F2_20337985_ChIP-ChIP_501MEL_Human1.12372494
112* ATF3_23680149_ChIP-Seq_GBM1-GSC_Human1.12180419
113* AHR_22903824_ChIP-Seq_MCF-7_Human1.12032775
114TBX3_20139965_ChIP-Seq_MESCs_Mouse1.11355826
115TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.11026715
116ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.10089504
117SMAD3_21741376_ChIP-Seq_EPCs_Human1.09985975
118TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.09724874
119P300_19829295_ChIP-Seq_ESCs_Human1.08604933
120BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.08391158
121NR3C1_21868756_ChIP-Seq_MCF10A_Human1.08046111
122FOXM1_23109430_ChIP-Seq_U2OS_Human1.07927173
123SMAD3_21741376_ChIP-Seq_HESCs_Human1.07795188
124HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.07460574
125* PPARG_20176806_ChIP-Seq_3T3-L1_Mouse1.06989148
126POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.06853420
127LXR_22292898_ChIP-Seq_THP-1_Human1.06164410
128FUS_26573619_Chip-Seq_HEK293_Human1.06133329
129JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.05691303
130NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.05682423
131SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.05514818
132GATA3_24758297_ChIP-Seq_MCF-7_Human1.05313128
133* ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.05020221
134RXR_22158963_ChIP-Seq_LIVER_Mouse1.04746367
135CREB1_26743006_Chip-Seq_LNCaP_Human1.04616288
136TCF7_22412390_ChIP-Seq_EML_Mouse1.03943047
137FOXA2_19822575_ChIP-Seq_HepG2_Human1.03874184
138TRIM28_17542650_ChIP-ChIP_NTERA2_Human1.03531340
139YAP1_20516196_ChIP-Seq_MESCs_Mouse1.03516382
140UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.02995702
141NCOR1_26117541_ChIP-Seq_K562_Human1.02842344
142TCF4_18268006_ChIP-ChIP_LS174T_Human1.02215451
143PCGF2_27294783_Chip-Seq_ESCs_Mouse1.02086038
144* ARNT_22903824_ChIP-Seq_MCF-7_Human1.01162543
145TP63_23658742_ChIP-Seq_EP156T_Human1.00788805
146SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.00363285
147SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.00111225
148MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.99793836
149EZH2_27294783_Chip-Seq_NPCs_Mouse0.98534862
150* WT1_25993318_ChIP-Seq_PODOCYTE_Human0.98345770
151* SOX2_20726797_ChIP-Seq_SW620_Human0.97464456
152RNF2_16625203_ChIP-ChIP_MESCs_Mouse0.96409557
153* TOP2B_26459242_ChIP-Seq_MCF-7_Human0.95164963
154* STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse0.94372909
155RNF2_18974828_ChIP-Seq_MESCs_Mouse0.94021990
156EZH2_18974828_ChIP-Seq_MESCs_Mouse0.94021990
157CDX2_22108803_ChIP-Seq_LS180_Human0.93741302

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004084_abnormal_cardiac_muscle3.55575966
2MP0004272_abnormal_basement_membrane3.30707040
3MP0003705_abnormal_hypodermis_morpholog3.22150178
4MP0002837_dystrophic_cardiac_calcinosis3.18336422
5MP0000751_myopathy3.09526254
6MP0010368_abnormal_lymphatic_system2.90718046
7MP0000749_muscle_degeneration2.87986144
8MP0004036_abnormal_muscle_relaxation2.78528177
9MP0004145_abnormal_muscle_electrophysio2.46112343
10MP0008438_abnormal_cutaneous_collagen2.45726541
11MP0000750_abnormal_muscle_regeneration2.28664954
12MP0005257_abnormal_intraocular_pressure2.26847903
13MP0004087_abnormal_muscle_fiber2.23375754
14MP0005623_abnormal_meninges_morphology2.22683489
15MP0001879_abnormal_lymphatic_vessel2.12799468
16MP0003646_muscle_fatigue2.11580757
17MP0005275_abnormal_skin_tensile2.07005000
18MP0005330_cardiomyopathy1.98274469
19MP0002269_muscular_atrophy1.92104534
20MP0001299_abnormal_eye_distance/1.92004867
21MP0003566_abnormal_cell_adhesion1.88620362
22MP0004215_abnormal_myocardial_fiber1.87488504
23MP0000747_muscle_weakness1.83542073
24MP0010630_abnormal_cardiac_muscle1.81994577
25MP0002106_abnormal_muscle_physiology1.81385692
26MP0004233_abnormal_muscle_weight1.81048956
27MP0002877_abnormal_melanocyte_morpholog1.80892538
28MP0000013_abnormal_adipose_tissue1.80518783
29MP0005620_abnormal_muscle_contractility1.79011574
30MP0009250_abnormal_appendicular_skeleto1.76572546
31MP0003283_abnormal_digestive_organ1.72867688
32MP0003279_aneurysm1.70731220
33MP0000759_abnormal_skeletal_muscle1.64963193
34MP0002972_abnormal_cardiac_muscle1.64439131
35MP0008775_abnormal_heart_ventricle1.61240237
36MP0004130_abnormal_muscle_cell1.60380357
37MP0006054_spinal_hemorrhage1.60221011
38MP0001542_abnormal_bone_strength1.59503124
39MP0005369_muscle_phenotype1.58541414
40MP0000537_abnormal_urethra_morphology1.57957374
41MP0003828_pulmonary_edema1.57403068
42MP0010352_gastrointestinal_tract_polyps1.56514032
43MP0006138_congestive_heart_failure1.56351496
44MP0000733_abnormal_muscle_development1.55099314
45MP0005503_abnormal_tendon_morphology1.54903105
46MP0005385_cardiovascular_system_phenoty1.49501992
47MP0001544_abnormal_cardiovascular_syste1.49501992
48MP0004185_abnormal_adipocyte_glucose1.47562454
49MP0005666_abnormal_adipose_tissue1.38305661
50MP0002108_abnormal_muscle_morphology1.36717926
51MP0010030_abnormal_orbit_morphology1.36717125
52MP0000003_abnormal_adipose_tissue1.35417634
53MP0005375_adipose_tissue_phenotype1.30039331
54MP0000762_abnormal_tongue_morphology1.27793487
55MP0002295_abnormal_pulmonary_circulatio1.27112847
56MP0002896_abnormal_bone_mineralization1.26040470
57MP0005670_abnormal_white_adipose1.21176887
58MP0005167_abnormal_blood-brain_barrier1.19081404
59MP0005409_darkened_coat_color1.18656983
60MP0004484_altered_response_of1.17324814
61MP0005595_abnormal_vascular_smooth1.17051111
62MP0010234_abnormal_vibrissa_follicle1.16826243
63MP0003937_abnormal_limbs/digits/tail_de1.16669721
64MP0005171_absent_coat_pigmentation1.14358976
65MP0002234_abnormal_pharynx_morphology1.14280736
66MP0000266_abnormal_heart_morphology1.12648110
67MP0004264_abnormal_extraembryonic_tissu1.12339296
68MP0002127_abnormal_cardiovascular_syste1.10901254
69MP0003567_abnormal_fetal_cardiomyocyte1.10253224
70MP0005076_abnormal_cell_differentiation1.09976872
71MP0000767_abnormal_smooth_muscle1.09020048
72MP0002925_abnormal_cardiovascular_devel1.07875780
73MP0003300_gastrointestinal_ulcer1.07846523
74MP0002128_abnormal_blood_circulation1.05447533
75MP0003755_abnormal_palate_morphology1.00990249
76MP0003941_abnormal_skin_development1.00362673
77MP0005197_abnormal_uvea_morphology0.98535599
78MP0009384_cardiac_valve_regurgitation0.98411377
79MP0001849_ear_inflammation0.93072442
80MP0005023_abnormal_wound_healing0.93033493
81MP0000163_abnormal_cartilage_morphology0.92339612
82MP0000534_abnormal_ureter_morphology0.91376864
83MP0004085_abnormal_heartbeat0.89368844
84MP0008961_abnormal_basal_metabolism0.87769620
85MP0003137_abnormal_impulse_conducting0.87339716
86MP0004134_abnormal_chest_morphology0.87118465
87MP0000432_abnormal_head_morphology0.86286681
88MP0003984_embryonic_growth_retardation0.85663226
89MP0005508_abnormal_skeleton_morphology0.85477672
90MP0003385_abnormal_body_wall0.85087640
91MP0002088_abnormal_embryonic_growth/wei0.84965444
92MP0003045_fibrosis0.84517380
93MP0002932_abnormal_joint_morphology0.83904664
94* MP0001614_abnormal_blood_vessel0.83176110
95MP0002115_abnormal_skeleton_extremities0.83130148
96MP0001958_emphysema0.82718711
97MP0002697_abnormal_eye_size0.82688950
98MP0004197_abnormal_fetal_growth/weight/0.82684968
99MP0009053_abnormal_anal_canal0.82264984
100MP0009780_abnormal_chondrocyte_physiolo0.80649003
101MP0003091_abnormal_cell_migration0.80272328
102MP0003115_abnormal_respiratory_system0.79809732
103MP0002086_abnormal_extraembryonic_tissu0.79203213
104MP0002109_abnormal_limb_morphology0.79086760
105MP0003221_abnormal_cardiomyocyte_apopto0.78648908
106MP0001661_extended_life_span0.78474291
107MP0003935_abnormal_craniofacial_develop0.78245467
108MP0000428_abnormal_craniofacial_morphol0.78018924
109MP0003119_abnormal_digestive_system0.76825751
110MP0000462_abnormal_digestive_system0.74996746
111MP0001243_abnormal_dermal_layer0.74558935
112MP0000049_abnormal_middle_ear0.74531400
113MP0005165_increased_susceptibility_to0.73473256
114MP0001784_abnormal_fluid_regulation0.73409685
115MP0003942_abnormal_urinary_system0.73315583
116MP0002168_other_aberrant_phenotype0.72733291
117MP0002233_abnormal_nose_morphology0.71803368
118MP0002060_abnormal_skin_morphology0.71623576
119MP0003950_abnormal_plasma_membrane0.71233001
120MP0002332_abnormal_exercise_endurance0.71070143
121MP0002282_abnormal_trachea_morphology0.70939294
122MP0005380_embryogenesis_phenotype0.70869389
123MP0001672_abnormal_embryogenesis/_devel0.70869389
124MP0002114_abnormal_axial_skeleton0.70475431
125MP0002177_abnormal_outer_ear0.70407429
126MP0001915_intracranial_hemorrhage0.68041191
127MP0004043_abnormal_pH_regulation0.67720713
128MP0009379_abnormal_foot_pigmentation0.67484078
129MP0000516_abnormal_urinary_system0.67250467
130MP0005164_abnormal_response_to0.67208189
131MP0002116_abnormal_craniofacial_bone0.65432212
132MP0005193_abnormal_anterior_eye0.64232111

Predicted human phenotypes

RankGene SetZ-score
1Increased connective tissue (HP:0009025)4.90578695
2Exercise-induced muscle cramps (HP:0003710)4.90414974
3Muscle fiber splitting (HP:0003555)4.90265978
4Type 1 muscle fiber predominance (HP:0003803)4.58568139
5Hyporeflexia of lower limbs (HP:0002600)4.55955069
6Exercise-induced myalgia (HP:0003738)4.27331254
7Muscle fiber inclusion bodies (HP:0100299)4.19924937
8Muscle fiber cytoplasmatic inclusion bodies (HP:0100303)4.02901365
9Difficulty running (HP:0009046)4.00141112
10Vascular tortuosity (HP:0004948)3.97436525
11Right ventricular cardiomyopathy (HP:0011663)3.87227450
12Sudden death (HP:0001699)3.82527108
13Arterial tortuosity (HP:0005116)3.79560878
14Ventricular tachycardia (HP:0004756)3.70964457
15Myoglobinuria (HP:0002913)3.68890778
16Calf muscle hypertrophy (HP:0008981)3.64860040
17Muscle hypertrophy of the lower extremities (HP:0008968)3.59083995
18Subaortic stenosis (HP:0001682)3.51721635
19Abnormality of the left ventricular outflow tract (HP:0011103)3.51721635
20Difficulty climbing stairs (HP:0003551)3.49643093
21Soft skin (HP:0000977)3.40944611
22Nemaline bodies (HP:0003798)3.40896078
23Protrusio acetabuli (HP:0003179)3.29769011
24Distal arthrogryposis (HP:0005684)3.21504875
25Abnormality of the calf musculature (HP:0001430)3.12591740
26EMG: myopathic abnormalities (HP:0003458)3.12084279
27Mesangial abnormality (HP:0001966)3.07686373
28Round ear (HP:0100830)3.07053669
29Cerebral aneurysm (HP:0004944)3.01223651
30Increased variability in muscle fiber diameter (HP:0003557)2.94199576
31Asymmetric septal hypertrophy (HP:0001670)2.92665163
32Mildly elevated creatine phosphokinase (HP:0008180)2.91278431
33Abnormality of skeletal muscle fiber size (HP:0012084)2.86927565
34Spondylolisthesis (HP:0003302)2.81244414
35Myotonia (HP:0002486)2.79616794
36Rhabdomyolysis (HP:0003201)2.79164568
37Follicular hyperkeratosis (HP:0007502)2.79010144
38Overgrowth (HP:0001548)2.78327590
39Neonatal short-limb short stature (HP:0008921)2.78321838
40Spinal rigidity (HP:0003306)2.77378251
41Lipoatrophy (HP:0100578)2.73989622
42Broad metatarsal (HP:0001783)2.73589573
43Abnormality of dentin (HP:0010299)2.72241897
44Hypoplastic ischia (HP:0003175)2.71997525
45Myopathic facies (HP:0002058)2.68178215
46Wormian bones (HP:0002645)2.63349150
47Limited hip movement (HP:0008800)2.62709200
48Ulnar deviation of the wrist (HP:0003049)2.59854406
49Lymphangioma (HP:0100764)2.59523254
50Slender build (HP:0001533)2.58469842
51Hypoglycemic coma (HP:0001325)2.56347225
52Mitral valve prolapse (HP:0001634)2.55630819
53Abnormality of the ischium (HP:0003174)2.53475814
54Premature rupture of membranes (HP:0001788)2.49732679
55Hyperinsulinemic hypoglycemia (HP:0000825)2.47929835
56Rectal prolapse (HP:0002035)2.47581796
57Ankle contracture (HP:0006466)2.44314708
58Bundle branch block (HP:0011710)2.42790221
59Muscle stiffness (HP:0003552)2.39977861
60Focal segmental glomerulosclerosis (HP:0000097)2.36910409
61Atrial fibrillation (HP:0005110)2.35802779
62Aneurysm (HP:0002617)2.35190860
63Absent phalangeal crease (HP:0006109)2.30262947
64Dilated cardiomyopathy (HP:0001644)2.27226134
65Distal lower limb muscle weakness (HP:0009053)2.25454776
66Cervical subluxation (HP:0003308)2.25266105
67Scapular winging (HP:0003691)2.21195532
68Shallow orbits (HP:0000586)2.18137842
69Hyperglycemia (HP:0003074)2.17430928
70Blue sclerae (HP:0000592)2.14326222
71Bell-shaped thorax (HP:0001591)2.14321825
72Primary atrial arrhythmia (HP:0001692)2.14015324
73Supraventricular arrhythmia (HP:0005115)2.13515462
74Hypoplasia of the iris (HP:0007676)2.13338499
75Palpitations (HP:0001962)2.12494077
76Abnormal delivery (HP:0001787)2.05917124
77Areflexia of lower limbs (HP:0002522)2.05559874
78Aplasia/Hypoplasia of the pubic bone (HP:0009104)2.05345173
79Aortic regurgitation (HP:0001659)2.04949975
80Atrophic scars (HP:0001075)2.03896079
81Coronal craniosynostosis (HP:0004440)2.02889712
82Osteolytic defects of the hand bones (HP:0009699)2.02858093
83Osteolytic defects of the phalanges of the hand (HP:0009771)2.02858093
84Insulin-resistant diabetes mellitus (HP:0000831)2.01627458
85EMG: neuropathic changes (HP:0003445)2.01209148
86Supraventricular tachycardia (HP:0004755)2.00581840
87Neck muscle weakness (HP:0000467)1.99653306
88Hip contracture (HP:0003273)1.99464261
89Aortic aneurysm (HP:0004942)1.97191065
90Knee flexion contracture (HP:0006380)1.96937789
91Bladder diverticulum (HP:0000015)1.96182657
92Ventricular arrhythmia (HP:0004308)1.95151056
93Prolonged QT interval (HP:0001657)1.95041233
94Ketoacidosis (HP:0001993)1.93598851
95Wide anterior fontanel (HP:0000260)1.92862522
96Hypoalphalipoproteinemia (HP:0003233)1.91851279
97Limb-girdle muscle weakness (HP:0003325)1.91276621
98Metaphyseal cupping (HP:0003021)1.90705154
99Limb-girdle muscle atrophy (HP:0003797)1.89409862
100Generalized muscle weakness (HP:0003324)1.89343330
101Cardiovascular calcification (HP:0011915)1.88646783
102Abnormal atrioventricular conduction (HP:0005150)1.88569456
103Mitral regurgitation (HP:0001653)1.86986407
104Calcaneovalgus deformity (HP:0001848)1.86811177
105Genu recurvatum (HP:0002816)1.86157115
106Abnormality of the acetabulum (HP:0003170)1.85598785
107Vertebral arch anomaly (HP:0008438)1.85131563
108Joint laxity (HP:0001388)1.84083431
109Muscular dystrophy (HP:0003560)1.84003319
110Heart block (HP:0012722)1.83896445
111Dilatation of the ascending aorta (HP:0005111)1.83125411
112Syncope (HP:0001279)1.83057297
113Hematochezia (HP:0002573)1.82769012
114Mesomelia (HP:0003027)1.81912785
115Proximal amyotrophy (HP:0007126)1.81507045
116Breech presentation (HP:0001623)1.81035858
117Polycythemia (HP:0001901)1.80424302
118Abnormal finger flexion creases (HP:0006143)1.79376408
119Abnormality of the calcaneus (HP:0008364)1.79322589
120Frequent falls (HP:0002359)1.79176189
121Distal lower limb amyotrophy (HP:0008944)1.78959456
122Ulnar bowing (HP:0003031)1.78376069
123Atrioventricular block (HP:0001678)1.77702142
124Hyperextensible skin (HP:0000974)1.77400318
125Aortic valve stenosis (HP:0001650)1.76218215
126Elbow flexion contracture (HP:0002987)1.75932657
127Rimmed vacuoles (HP:0003805)1.75368926
128Bowel diverticulosis (HP:0005222)1.75171045
129Glomerulosclerosis (HP:0000096)1.74747293
130Mitral stenosis (HP:0001718)1.73831576
131Fragile skin (HP:0001030)1.73135621
132Ectopia lentis (HP:0001083)1.73129110
133Deformed tarsal bones (HP:0008119)1.72354375
134Pancreatic islet-cell hyperplasia (HP:0004510)1.72231129
135Aortic dissection (HP:0002647)1.71695426
136Wrist flexion contracture (HP:0001239)1.71359703
137Renal duplication (HP:0000075)1.71259265
138Absent frontal sinuses (HP:0002688)1.71223793
139Infantile muscular hypotonia (HP:0008947)1.68592568
140Facial diplegia (HP:0001349)1.67720024
141Large for gestational age (HP:0001520)1.67667365
142Ventricular fibrillation (HP:0001663)1.63731168
143Aplasia of the musculature (HP:0100854)1.60523422
144Delayed gross motor development (HP:0002194)1.57953160
145Coxa vara (HP:0002812)1.54453750

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TTN4.15797039
2TIE13.61864105
3TRIB33.60532934
4OBSCN3.35247870
5PKN22.88717485
6PDGFRA2.45710983
7LATS12.29397378
8PNCK2.19972577
9RIPK12.18852613
10AKT32.06774175
11EPHB22.04240120
12KDR2.00374699
13PDK31.99415492
14PDK41.99415492
15ERN11.93073113
16LMTK21.86996502
17NEK11.85320713
18PHKG21.81662686
19PHKG11.81662686
20PTK61.77734522
21WNK41.74439064
22DMPK1.73363107
23LIMK11.69626826
24EPHA21.63173528
25TGFBR21.59383437
26PDK21.51966523
27INSRR1.51255624
28CDK121.47849622
29PBK1.41451314
30ERBB41.41137661
31MAP3K101.39948784
32TGFBR11.36652603
33NTRK11.34798219
34FER1.29285232
35MAP2K31.27579759
36PAK41.27213104
37PRKD31.24423429
38MET1.23151206
39MYLK1.21229904
40SIK11.20296991
41MAP3K31.19072848
42DDR21.18970064
43PTK21.14986106
44STK38L1.12662514
45MAP3K121.12032671
46FRK1.08992531
47BCKDK1.08218266
48MUSK1.06652810
49MOS1.06467122
50EEF2K1.04416943
51MTOR1.03421354
52PIK3CA1.03163135
53LRRK21.00936912
54PINK10.98396324
55PAK20.94981856
56LATS20.93986634
57PASK0.93527447
58FLT30.93310484
59EPHB10.93058554
60MAP3K70.92405765
61MELK0.91708405
62PAK30.89245560
63PDGFRB0.86971389
64ACVR1B0.86066271
65PRKG20.82825144
66STK30.82572076
67ICK0.82374285
68TESK10.79722322
69ADRBK10.76881154
70WEE10.75712128
71NEK90.75075066
72BMX0.74268099
73MAP2K20.73210586
74PRKD10.73097509
75CDK80.72945236
76PIK3CG0.72702536
77ROCK10.72534739
78BMPR1B0.71884584
79TNIK0.71705983
80PTK2B0.71204501
81STK380.70766426
82ERBB30.70015002
83BRSK20.69836219
84MAPKAPK30.69454522
85SCYL20.68376872
86ABL20.67428532
87ROCK20.67276768
88NME10.65806133
89FGFR40.64701524
90TRPM70.64677292
91CAMK1D0.64188701
92RPS6KB20.64066262
93FGFR10.62501734
94CDC42BPA0.60930760
95ILK0.59533814
96PRKAA20.58993092
97MAPK70.58475245
98PRKAA10.57639140
99RET0.57626633
100DYRK1B0.55369005
101PRKCE0.55067014
102GRK10.53335675
103MAP3K20.52832780
104MAP2K10.51954919
105STK100.50863937
106CAMK1G0.50289488
107CAMK2G0.49962268
108MAPK150.49796443
109WNK10.49341229
110GSK3A0.48824257
111EPHA30.48021121
112AKT20.47813102
113NEK20.47792173
114NUAK10.47729996
115PRKD20.46284695
116STK390.44240089
117MAP3K10.44217625
118PLK20.43735141
119PRKG10.43596953
120BCR0.42667701
121FGFR30.42582821
122MAP3K80.42397287
123CDK60.42369846
124CAMK2D0.42015502
125DAPK30.38926792
126CDK90.37271290
127MARK30.35648147
128TAOK10.32775248
129MST1R0.32437807
130PAK60.32372461
131HIPK20.32083713
132PRKCH0.32034475
133GRK70.31419237
134MAP3K60.30518479
135STK240.29565290
136MAPK120.27769912
137CAMK2A0.26987598
138NLK0.25851132
139ZAK0.23712146
140TTK0.23552659
141KSR20.22750387

Predicted pathways (KEGG)

RankGene SetZ-score
1Citrate cycle (TCA cycle)_Homo sapiens_hsa000203.81405104
2Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054103.03069673
3Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054122.88528248
4Dilated cardiomyopathy_Homo sapiens_hsa054142.80986328
5ECM-receptor interaction_Homo sapiens_hsa045122.77183230
62-Oxocarboxylic acid metabolism_Homo sapiens_hsa012102.44415241
7Focal adhesion_Homo sapiens_hsa045102.28334587
8Maturity onset diabetes of the young_Homo sapiens_hsa049502.28170765
9Adherens junction_Homo sapiens_hsa045202.15980249
10Protein digestion and absorption_Homo sapiens_hsa049742.08014522
11Tight junction_Homo sapiens_hsa045301.77842685
12Insulin resistance_Homo sapiens_hsa049311.76149662
13Fatty acid degradation_Homo sapiens_hsa000711.73242295
14Propanoate metabolism_Homo sapiens_hsa006401.68663593
15Small cell lung cancer_Homo sapiens_hsa052221.57103221
16Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.53051411
17Starch and sucrose metabolism_Homo sapiens_hsa005001.50513537
18Proteoglycans in cancer_Homo sapiens_hsa052051.47973008
19Amoebiasis_Homo sapiens_hsa051461.46614257
20Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.45977594
21Cardiac muscle contraction_Homo sapiens_hsa042601.42672820
22Carbon metabolism_Homo sapiens_hsa012001.41992575
23Viral myocarditis_Homo sapiens_hsa054161.37164413
24Lysine degradation_Homo sapiens_hsa003101.36412628
25Glucagon signaling pathway_Homo sapiens_hsa049221.36304874
26Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.34814675
27Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.29368783
28Glycolysis / Gluconeogenesis_Homo sapiens_hsa000101.28562282
29Hippo signaling pathway_Homo sapiens_hsa043901.24787493
30Galactose metabolism_Homo sapiens_hsa000521.24069907
31Fat digestion and absorption_Homo sapiens_hsa049751.22407660
32AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.19116597
33Central carbon metabolism in cancer_Homo sapiens_hsa052301.18054269
34Insulin signaling pathway_Homo sapiens_hsa049101.17538991
35AMPK signaling pathway_Homo sapiens_hsa041521.16958614
36Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.15990882
37Bladder cancer_Homo sapiens_hsa052191.15478109
38Fatty acid metabolism_Homo sapiens_hsa012121.12331577
39Adipocytokine signaling pathway_Homo sapiens_hsa049201.09551989
40Basal cell carcinoma_Homo sapiens_hsa052171.09518013
41Leukocyte transendothelial migration_Homo sapiens_hsa046701.06369102
42Pyruvate metabolism_Homo sapiens_hsa006201.05850930
43Dorso-ventral axis formation_Homo sapiens_hsa043201.01108137
44Axon guidance_Homo sapiens_hsa043600.98710910
45Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.98693102
46Renin-angiotensin system_Homo sapiens_hsa046140.97631016
47Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.96459816
48PPAR signaling pathway_Homo sapiens_hsa033200.95466197
49Thyroid cancer_Homo sapiens_hsa052160.95246158
50mTOR signaling pathway_Homo sapiens_hsa041500.94521203
51HIF-1 signaling pathway_Homo sapiens_hsa040660.93141597
52Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.92462512
53Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.92154453
54PI3K-Akt signaling pathway_Homo sapiens_hsa041510.91684039
55cGMP-PKG signaling pathway_Homo sapiens_hsa040220.91673881
56MicroRNAs in cancer_Homo sapiens_hsa052060.90225382
57Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.88057487
58Notch signaling pathway_Homo sapiens_hsa043300.88011648
59Type II diabetes mellitus_Homo sapiens_hsa049300.83839716
60Gap junction_Homo sapiens_hsa045400.82762048
61Thyroid hormone signaling pathway_Homo sapiens_hsa049190.82680556
62TGF-beta signaling pathway_Homo sapiens_hsa043500.81256686
63Carbohydrate digestion and absorption_Homo sapiens_hsa049730.80571743
64Complement and coagulation cascades_Homo sapiens_hsa046100.78766714
65Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.78473792
66Selenocompound metabolism_Homo sapiens_hsa004500.77525640
67Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.76406787
68Longevity regulating pathway - mammal_Homo sapiens_hsa042110.76303586
69Calcium signaling pathway_Homo sapiens_hsa040200.75747226
70Hedgehog signaling pathway_Homo sapiens_hsa043400.75117168
71Regulation of actin cytoskeleton_Homo sapiens_hsa048100.74610030
72Glycosaminoglycan degradation_Homo sapiens_hsa005310.74312439
73Chronic myeloid leukemia_Homo sapiens_hsa052200.73963487
74Renal cell carcinoma_Homo sapiens_hsa052110.72786815
75Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.70692623
76Bile secretion_Homo sapiens_hsa049760.70626989
77Pathways in cancer_Homo sapiens_hsa052000.69602063
78Endometrial cancer_Homo sapiens_hsa052130.68988310
79Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.68738207
80Tryptophan metabolism_Homo sapiens_hsa003800.68702188
81Biosynthesis of amino acids_Homo sapiens_hsa012300.68596410
82Fructose and mannose metabolism_Homo sapiens_hsa000510.68508613
83Oxytocin signaling pathway_Homo sapiens_hsa049210.67123561
84Sulfur metabolism_Homo sapiens_hsa009200.64051633
85Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.63796215
86Glioma_Homo sapiens_hsa052140.62895002
87Glutathione metabolism_Homo sapiens_hsa004800.62200469
88Renin secretion_Homo sapiens_hsa049240.61899567
89Vascular smooth muscle contraction_Homo sapiens_hsa042700.61447119
90Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.61249974
91VEGF signaling pathway_Homo sapiens_hsa043700.61095462
92Prostate cancer_Homo sapiens_hsa052150.60658843
93Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.59663484
94Insulin secretion_Homo sapiens_hsa049110.59369532
95Rap1 signaling pathway_Homo sapiens_hsa040150.56757144
96FoxO signaling pathway_Homo sapiens_hsa040680.55114360
97Nitrogen metabolism_Homo sapiens_hsa009100.54644400
98Platelet activation_Homo sapiens_hsa046110.52999987
99Toxoplasmosis_Homo sapiens_hsa051450.52604831
100Estrogen signaling pathway_Homo sapiens_hsa049150.52587817
101Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.51820882
102Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.50622694
103Pancreatic secretion_Homo sapiens_hsa049720.49478388
104Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.49042319
105p53 signaling pathway_Homo sapiens_hsa041150.48961463
106Arginine biosynthesis_Homo sapiens_hsa002200.48851843
107Arginine and proline metabolism_Homo sapiens_hsa003300.48359294
108Circadian rhythm_Homo sapiens_hsa047100.48325024
109Melanoma_Homo sapiens_hsa052180.47802403
110Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.47776877
111Thyroid hormone synthesis_Homo sapiens_hsa049180.46831300
112Histidine metabolism_Homo sapiens_hsa003400.46766209
113Ras signaling pathway_Homo sapiens_hsa040140.45727873
114beta-Alanine metabolism_Homo sapiens_hsa004100.45153850
115cAMP signaling pathway_Homo sapiens_hsa040240.42969658
116Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.42624142
117HTLV-I infection_Homo sapiens_hsa051660.41828751
118Wnt signaling pathway_Homo sapiens_hsa043100.41612793
119Gastric acid secretion_Homo sapiens_hsa049710.41056132
120Melanogenesis_Homo sapiens_hsa049160.40692403
121Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.40020145
122Folate biosynthesis_Homo sapiens_hsa007900.37778806
123Phospholipase D signaling pathway_Homo sapiens_hsa040720.37507463
124Protein export_Homo sapiens_hsa030600.35751708
125Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.35497743
126Salivary secretion_Homo sapiens_hsa049700.34970922
127Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.33379377
128Prolactin signaling pathway_Homo sapiens_hsa049170.31403105
129Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.31025936
130Colorectal cancer_Homo sapiens_hsa052100.29782700

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