Rank | Gene Set | Z-score |
---|---|---|
1 | peptidyl-arginine omega-N-methylation (GO:0035247) | 4.50491240 |
2 | pre-miRNA processing (GO:0031054) | 4.43536116 |
3 | retrograde vesicle-mediated transport, Golgi to ER (GO:0006890) | 4.36821218 |
4 | regulation of translational fidelity (GO:0006450) | 4.33194280 |
5 | protein retention in ER lumen (GO:0006621) | 4.27776440 |
6 | regulation of translational termination (GO:0006449) | 4.26648559 |
7 | peptidyl-arginine N-methylation (GO:0035246) | 4.22990499 |
8 | peptidyl-arginine methylation (GO:0018216) | 4.22990499 |
9 | DNA unwinding involved in DNA replication (GO:0006268) | 4.14010086 |
10 | maintenance of protein localization in endoplasmic reticulum (GO:0035437) | 4.11214586 |
11 | spliceosomal tri-snRNP complex assembly (GO:0000244) | 3.86031280 |
12 | nuclear pore complex assembly (GO:0051292) | 3.85769488 |
13 | layer formation in cerebral cortex (GO:0021819) | 3.81389408 |
14 | regulation of mammary gland epithelial cell proliferation (GO:0033599) | 3.79471430 |
15 | nuclear pore organization (GO:0006999) | 3.76725817 |
16 | negative regulation of cell size (GO:0045792) | 3.68922997 |
17 | dosage compensation (GO:0007549) | 3.67490752 |
18 | peptidyl-lysine dimethylation (GO:0018027) | 3.62146439 |
19 | histone arginine methylation (GO:0034969) | 3.58486034 |
20 | proline biosynthetic process (GO:0006561) | 3.55091072 |
21 | glucocorticoid receptor signaling pathway (GO:0042921) | 3.53051348 |
22 | negative regulation of microtubule polymerization (GO:0031115) | 3.52572940 |
23 | regulation of NFAT protein import into nucleus (GO:0051532) | 3.51112768 |
24 | cell-substrate adherens junction assembly (GO:0007045) | 3.50748221 |
25 | focal adhesion assembly (GO:0048041) | 3.50748221 |
26 | heterochromatin organization (GO:0070828) | 3.50171442 |
27 | semaphorin-plexin signaling pathway (GO:0071526) | 3.43052455 |
28 | NLS-bearing protein import into nucleus (GO:0006607) | 3.38323095 |
29 | nuclear envelope disassembly (GO:0051081) | 3.33293744 |
30 | membrane disassembly (GO:0030397) | 3.33293744 |
31 | mitotic nuclear envelope disassembly (GO:0007077) | 3.31296697 |
32 | activation of Rac GTPase activity (GO:0032863) | 3.29929650 |
33 | negative regulation of mRNA splicing, via spliceosome (GO:0048025) | 3.28535676 |
34 | negative regulation of histone methylation (GO:0031061) | 3.24829454 |
35 | folic acid-containing compound biosynthetic process (GO:0009396) | 3.23831117 |
36 | COPI coating of Golgi vesicle (GO:0048205) | 3.22559905 |
37 | Golgi transport vesicle coating (GO:0048200) | 3.22559905 |
38 | convergent extension (GO:0060026) | 3.14644904 |
39 | cell-substrate junction assembly (GO:0007044) | 3.11812533 |
40 | apoptotic process involved in morphogenesis (GO:0060561) | 3.11294724 |
41 | protein localization to endosome (GO:0036010) | 3.06494340 |
42 | establishment of nucleus localization (GO:0040023) | 3.05213045 |
43 | pentose-phosphate shunt (GO:0006098) | 3.04315060 |
44 | Wnt signaling pathway, planar cell polarity pathway (GO:0060071) | 3.04184184 |
45 | regulation of RNA export from nucleus (GO:0046831) | 3.02883278 |
46 | protein-DNA complex disassembly (GO:0032986) | 3.02251646 |
47 | nucleosome disassembly (GO:0006337) | 3.02251646 |
48 | pyrimidine nucleobase catabolic process (GO:0006208) | 3.00337563 |
49 | protein localization to kinetochore (GO:0034501) | 3.00332771 |
50 | regulation of attachment of spindle microtubules to kinetochore (GO:0051988) | 3.00070513 |
51 | regulation of glucose import in response to insulin stimulus (GO:2001273) | 2.99545981 |
52 | epithelial cell-cell adhesion (GO:0090136) | 2.99123395 |
53 | positive regulation of RNA splicing (GO:0033120) | 2.97821191 |
54 | cytoskeletal anchoring at plasma membrane (GO:0007016) | 2.97184518 |
55 | regulation of Arp2/3 complex-mediated actin nucleation (GO:0034315) | 2.97182818 |
56 | histone H2A monoubiquitination (GO:0035518) | 2.96716594 |
57 | ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway (GO:004316 | 2.95761165 |
58 | cerebellar Purkinje cell layer development (GO:0021680) | 2.93699084 |
59 | cell migration in hindbrain (GO:0021535) | 2.92758540 |
60 | positive regulation of synapse maturation (GO:0090129) | 2.92293860 |
61 | basement membrane organization (GO:0071711) | 2.92001131 |
62 | regulation of establishment of planar polarity (GO:0090175) | 2.89747668 |
63 | cell-cell junction maintenance (GO:0045217) | 2.89624365 |
64 | hippo signaling (GO:0035329) | 2.89465445 |
65 | glucose 6-phosphate metabolic process (GO:0051156) | 2.87672921 |
66 | nuclear envelope organization (GO:0006998) | 2.87471295 |
67 | dichotomous subdivision of an epithelial terminal unit (GO:0060600) | 2.86997976 |
68 | intracellular estrogen receptor signaling pathway (GO:0030520) | 2.86765862 |
69 | corticosteroid receptor signaling pathway (GO:0031958) | 2.85994841 |
70 | mitotic nuclear envelope reassembly (GO:0007084) | 2.84395753 |
71 | nuclear envelope reassembly (GO:0031468) | 2.84395753 |
72 | alternative mRNA splicing, via spliceosome (GO:0000380) | 2.82630249 |
73 | polarized epithelial cell differentiation (GO:0030859) | 2.82597058 |
74 | negative regulation of RNA splicing (GO:0033119) | 2.80198958 |
75 | positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling | 2.79530688 |
76 | vesicle coating (GO:0006901) | 2.77800387 |
77 | hemidesmosome assembly (GO:0031581) | 2.76883082 |
78 | positive regulation of extrinsic apoptotic signaling pathway in absence of ligand (GO:2001241) | 2.76711614 |
79 | embryonic foregut morphogenesis (GO:0048617) | 2.76444378 |
80 | mRNA stabilization (GO:0048255) | 2.75074765 |
81 | RNA stabilization (GO:0043489) | 2.75074765 |
82 | DNA duplex unwinding (GO:0032508) | 2.71087814 |
83 | 3-UTR-mediated mRNA stabilization (GO:0070935) | 2.70619670 |
84 | barbed-end actin filament capping (GO:0051016) | 2.68946166 |
85 | protein localization to microtubule (GO:0035372) | 2.68747234 |
86 | DNA geometric change (GO:0032392) | 2.67577138 |
87 | negative regulation of mRNA metabolic process (GO:1903312) | 2.66835228 |
88 | cellular response to epidermal growth factor stimulus (GO:0071364) | 2.65974195 |
89 | epithelial cell differentiation involved in prostate gland development (GO:0060742) | 2.65363740 |
90 | adherens junction assembly (GO:0034333) | 2.63877055 |
91 | glucose catabolic process (GO:0006007) | 2.63297073 |
92 | protein maturation by protein folding (GO:0022417) | 2.62674723 |
93 | protein complex localization (GO:0031503) | 2.62610456 |
94 | NADPH regeneration (GO:0006740) | 2.62497231 |
95 | paraxial mesoderm development (GO:0048339) | 2.62292816 |
96 | regulation of early endosome to late endosome transport (GO:2000641) | 2.62091880 |
97 | sister chromatid segregation (GO:0000819) | 2.61470813 |
98 | cochlea morphogenesis (GO:0090103) | 2.60665741 |
99 | glial cell proliferation (GO:0014009) | 2.59991569 |
100 | planar cell polarity pathway involved in neural tube closure (GO:0090179) | 2.59110726 |
101 | regulation of translational elongation (GO:0006448) | 2.58349021 |
102 | establishment of apical/basal cell polarity (GO:0035089) | 2.58075670 |
103 | regulation of establishment of planar polarity involved in neural tube closure (GO:0090178) | 2.57774745 |
104 | mitotic sister chromatid cohesion (GO:0007064) | 2.57652049 |
105 | regulation of chromatin binding (GO:0035561) | 2.57103602 |
106 | negative regulation of mRNA processing (GO:0050686) | 2.56810521 |
107 | IMP biosynthetic process (GO:0006188) | 2.56479713 |
108 | gene silencing by RNA (GO:0031047) | 2.55841274 |
109 | regulation of branching involved in prostate gland morphogenesis (GO:0060687) | 2.55624618 |
110 | pore complex assembly (GO:0046931) | 2.55346653 |
111 | response to epidermal growth factor (GO:0070849) | 2.55058915 |
112 | amyloid precursor protein catabolic process (GO:0042987) | 2.54393128 |
113 | negative regulation of catenin import into nucleus (GO:0035414) | 2.53875163 |
114 | positive regulation of SMAD protein import into nucleus (GO:0060391) | 2.52730661 |
115 | stress fiber assembly (GO:0043149) | 2.52418789 |
116 | mitotic chromosome condensation (GO:0007076) | 2.52417929 |
117 | glycolytic process (GO:0006096) | 2.51842297 |
118 | protein export from nucleus (GO:0006611) | 2.51168339 |
119 | gene silencing (GO:0016458) | 2.49874541 |
120 | desmosome organization (GO:0002934) | 2.49302732 |
121 | sodium ion export (GO:0071436) | 2.48707908 |
122 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 2.48437380 |
123 | stress granule assembly (GO:0034063) | 2.47181914 |
124 | regulation of sister chromatid cohesion (GO:0007063) | 2.47125382 |
125 | peptidyl-arginine modification (GO:0018195) | 2.46559442 |
126 | ectodermal placode formation (GO:0060788) | 2.45885619 |
127 | regulation of nucleobase-containing compound transport (GO:0032239) | 2.43906848 |
128 | adherens junction organization (GO:0034332) | 2.43509204 |
129 | cellular protein complex localization (GO:0034629) | 2.43242763 |
130 | regulation of hippo signaling (GO:0035330) | 2.43081325 |
131 | regulation of SMAD protein import into nucleus (GO:0060390) | 2.42963127 |
132 | branching involved in mammary gland duct morphogenesis (GO:0060444) | 2.42522188 |
133 | regulation of mitotic spindle organization (GO:0060236) | 2.41274669 |
134 | cytoplasmic mRNA processing body assembly (GO:0033962) | 2.40111121 |
135 | mitotic spindle organization (GO:0007052) | 2.40003660 |
136 | chromatin assembly (GO:0031497) | 2.39855723 |
137 | modulation by virus of host morphology or physiology (GO:0019048) | 2.39475089 |
138 | positive regulation of receptor biosynthetic process (GO:0010870) | 2.38885468 |
139 | regulation of spindle organization (GO:0090224) | 2.38206444 |
140 | positive regulation of blood vessel endothelial cell migration (GO:0043536) | 2.37864746 |
141 | eye morphogenesis (GO:0048592) | 2.36546242 |
142 | regulation of DNA damage checkpoint (GO:2000001) | 2.36531605 |
143 | activation of signaling protein activity involved in unfolded protein response (GO:0006987) | 2.35886748 |
144 | camera-type eye morphogenesis (GO:0048593) | 2.35665004 |
145 | protein targeting to plasma membrane (GO:0072661) | 2.35302344 |
146 | positive regulation of nuclease activity (GO:0032075) | 2.34622189 |
147 | maternal placenta development (GO:0001893) | 2.34587900 |
148 | snRNA metabolic process (GO:0016073) | 2.34401024 |
149 | mitochondrion transport along microtubule (GO:0047497) | 2.33877619 |
150 | establishment of mitochondrion localization, microtubule-mediated (GO:0034643) | 2.33877619 |
151 | positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling | 2.32532884 |
152 | regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway | 2.32532884 |
153 | endoplasmic reticulum unfolded protein response (GO:0030968) | 2.32404977 |
154 | DNA replication-dependent nucleosome organization (GO:0034723) | 2.31706565 |
155 | DNA replication-dependent nucleosome assembly (GO:0006335) | 2.31706565 |
156 | regulation of protein heterodimerization activity (GO:0043497) | 2.31022537 |
157 | gastrulation with mouth forming second (GO:0001702) | 2.30812383 |
158 | negative regulation of organelle assembly (GO:1902116) | 2.29837089 |
Rank | Gene Set | Z-score |
---|---|---|
1 | E2F7_22180533_ChIP-Seq_HELA_Human | 5.94063591 |
2 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 4.09760844 |
3 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 3.90631073 |
4 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 3.46277258 |
5 | MYC_22102868_ChIP-Seq_BL_Human | 3.44073340 |
6 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 2.74979722 |
7 | ZFP281_18757296_ChIP-ChIP_E14_Mouse | 2.62109665 |
8 | ZFP281_18358816_ChIP-ChIP_MESCs_Mouse | 2.55646047 |
9 | ZNF263_19887448_ChIP-Seq_K562_Human | 2.34664980 |
10 | EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 2.33312385 |
11 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.25128126 |
12 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 2.24822325 |
13 | KDM2B_26808549_Chip-Seq_DND41_Human | 2.18715733 |
14 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 2.12203840 |
15 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 2.10984618 |
16 | CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat | 2.08600083 |
17 | * KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 2.03357286 |
18 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 2.03286860 |
19 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 2.00146585 |
20 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 1.99610443 |
21 | ZFP281_27345836_Chip-Seq_ESCs_Mouse | 1.96899776 |
22 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 1.93205113 |
23 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 1.91389366 |
24 | TCF3_18467660_ChIP-ChIP_MESCs_Mouse | 1.91118953 |
25 | SALL4_18804426_ChIP-ChIP_MESCs_Mouse | 1.89755865 |
26 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 1.87456070 |
27 | WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse | 1.83610847 |
28 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.83319805 |
29 | ZIC3_20872845_ChIP-ChIP_MESCs_Mouse | 1.79392036 |
30 | VDR_21846776_ChIP-Seq_THP-1_Human | 1.78312646 |
31 | DMRT1_23473982_ChIP-Seq_TESTES_Mouse | 1.76027386 |
32 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.76001150 |
33 | TCF7_22412390_ChIP-Seq_EML_Mouse | 1.73636084 |
34 | CLOCK_20551151_ChIP-Seq_293T_Human | 1.65478292 |
35 | SMAD3_22036565_ChIP-Seq_ESCs_Mouse | 1.65254588 |
36 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.65026835 |
37 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 1.63119200 |
38 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 1.62617633 |
39 | P300_27058665_Chip-Seq_ZR-75-30cells_Human | 1.62274740 |
40 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 1.61915511 |
41 | CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 1.61739647 |
42 | SMAD1_18555785_ChIP-Seq_MESCs_Mouse | 1.59280834 |
43 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.57846073 |
44 | KDM2B_26808549_Chip-Seq_JURKAT_Human | 1.57389305 |
45 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 1.56772835 |
46 | KDM2B_26808549_Chip-Seq_K562_Human | 1.54316224 |
47 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 1.53620317 |
48 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 1.51159848 |
49 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 1.49405128 |
50 | DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 1.49308063 |
51 | TET1_21451524_ChIP-Seq_MESCs_Mouse | 1.48008646 |
52 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 1.47166446 |
53 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 1.45867855 |
54 | LXR_22292898_ChIP-Seq_THP-1_Human | 1.45626879 |
55 | ATF3_27146783_Chip-Seq_COLON_Human | 1.44140546 |
56 | KLF4_18555785_ChIP-Seq_MESCs_Mouse | 1.43661869 |
57 | CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse | 1.43129056 |
58 | KLF4_18358816_ChIP-ChIP_MESCs_Mouse | 1.42725332 |
59 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.42423396 |
60 | ZFX_18555785_ChIP-Seq_MESCs_Mouse | 1.40511972 |
61 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 1.40057030 |
62 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.38563907 |
63 | EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human | 1.36570275 |
64 | AR_21909140_ChIP-Seq_LNCAP_Human | 1.36184509 |
65 | KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.36130766 |
66 | NANOG_21062744_ChIP-ChIP_HESCs_Human | 1.35093444 |
67 | EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse | 1.33334280 |
68 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.32145196 |
69 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 1.32102543 |
70 | PKCTHETA_26484144_Chip-Seq_BREAST_Human | 1.29859352 |
71 | SA1_27219007_Chip-Seq_ERYTHROID_Human | 1.29215882 |
72 | CREM_20920259_ChIP-Seq_GC1-SPG_Mouse | 1.28643928 |
73 | HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse | 1.28593742 |
74 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.27827551 |
75 | SMC4_20622854_ChIP-Seq_HELA_Human | 1.27816161 |
76 | CHD1_26751641_Chip-Seq_LNCaP_Human | 1.26868794 |
77 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.26741032 |
78 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.26411262 |
79 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.25993969 |
80 | CTCF_27219007_Chip-Seq_ERYTHROID_Human | 1.25696262 |
81 | * CREB1_26743006_Chip-Seq_LNCaP_Human | 1.25684628 |
82 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.24476237 |
83 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.23626874 |
84 | ZNF652_21678463_ChIP-ChIP_ZR75-1_Human | 1.23354999 |
85 | SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 1.21901299 |
86 | KDM5A_27292631_Chip-Seq_BREAST_Human | 1.21272005 |
87 | HIF1A_21447827_ChIP-Seq_MCF-7_Human | 1.19453811 |
88 | RUNX2_24764292_ChIP-Seq_MC3T3_Mouse | 1.18357334 |
89 | RACK7_27058665_Chip-Seq_MCF-7_Human | 1.18067340 |
90 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.17449509 |
91 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 1.17178955 |
92 | UTX_26944678_Chip-Seq_JUKART_Human | 1.16265812 |
93 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.15962807 |
94 | NANOG_18700969_ChIP-ChIP_MESCs_Mouse | 1.15882419 |
95 | * UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human | 1.15333556 |
96 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.14015961 |
97 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 1.12804206 |
98 | FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human | 1.12083497 |
99 | TP53_22127205_ChIP-Seq_IMR90_Human | 1.12061268 |
100 | SETDB1_19884255_ChIP-Seq_MESCs_Mouse | 1.11986602 |
101 | NANOG_18347094_ChIP-ChIP_MESCs_Mouse | 1.11884336 |
102 | DNAJC2_21179169_ChIP-ChIP_NT2_Human | 1.11881292 |
103 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 1.11567852 |
104 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.08521853 |
105 | TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 1.07350219 |
106 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 1.06781115 |
107 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 1.05988908 |
108 | TFAP2A_17053090_ChIP-ChIP_MCF-7_Human | 1.04720743 |
109 | HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse | 1.04602332 |
110 | NCOR1_26117541_ChIP-Seq_K562_Human | 1.04303377 |
111 | SOX2_18358816_ChIP-ChIP_MESCs_Mouse | 1.03600067 |
112 | OCT4_18692474_ChIP-Seq_MEFs_Mouse | 1.02445540 |
113 | KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.02235838 |
114 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.01317634 |
115 | P68_20966046_ChIP-Seq_HELA_Human | 1.00691412 |
116 | ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.00613880 |
117 | RUNX1_27514584_Chip-Seq_MCF-7_Human | 1.00045584 |
118 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 0.99644408 |
119 | FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human | 0.99621421 |
120 | PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse | 0.99370815 |
121 | SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 0.98958260 |
122 | CREB1_26743006_Chip-Seq_LNCaP-abl_Human | 0.98858545 |
123 | SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse | 0.98807870 |
124 | CNOT3_19339689_ChIP-ChIP_MESCs_Mouse | 0.98610408 |
125 | UBF1/2_26484160_Chip-Seq_HMECs_Human | 0.98585414 |
126 | MAF_26560356_Chip-Seq_TH1_Human | 0.98079852 |
127 | NACC1_18358816_ChIP-ChIP_MESCs_Mouse | 0.97785331 |
128 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 0.97525024 |
129 | TCF3_18692474_ChIP-Seq_MEFs_Mouse | 0.97430732 |
130 | SREBP1_19666523_ChIP-Seq_LIVER_Mouse | 0.97011349 |
131 | TET1_21490601_ChIP-Seq_MESCs_Mouse | 0.96890746 |
132 | RARB_27405468_Chip-Seq_BRAIN_Mouse | 0.95715482 |
133 | * CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 0.95094715 |
134 | NR0B1_18358816_ChIP-ChIP_MESCs_Mouse | 0.94081264 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0003705_abnormal_hypodermis_morpholog | 3.47624816 |
2 | MP0010352_gastrointestinal_tract_polyps | 3.42132253 |
3 | MP0000537_abnormal_urethra_morphology | 3.20090095 |
4 | MP0005076_abnormal_cell_differentiation | 2.99726171 |
5 | MP0008438_abnormal_cutaneous_collagen | 2.44940675 |
6 | MP0003123_paternal_imprinting | 2.42334937 |
7 | MP0000569_abnormal_digit_pigmentation | 2.39779025 |
8 | MP0001730_embryonic_growth_arrest | 2.25418904 |
9 | MP0003111_abnormal_nucleus_morphology | 2.21447596 |
10 | MP0005451_abnormal_body_composition | 2.20325653 |
11 | MP0010234_abnormal_vibrissa_follicle | 2.13404434 |
12 | MP0005257_abnormal_intraocular_pressure | 2.06455925 |
13 | MP0010030_abnormal_orbit_morphology | 2.02276452 |
14 | MP0001849_ear_inflammation | 2.01378432 |
15 | MP0000566_synostosis | 2.00733349 |
16 | MP0002084_abnormal_developmental_patter | 1.99444743 |
17 | MP0004957_abnormal_blastocyst_morpholog | 1.99128819 |
18 | MP0000579_abnormal_nail_morphology | 1.98088070 |
19 | MP0002249_abnormal_larynx_morphology | 1.95943176 |
20 | MP0004859_abnormal_synaptic_plasticity | 1.94588902 |
21 | MP0004272_abnormal_basement_membrane | 1.93791959 |
22 | MP0003283_abnormal_digestive_organ | 1.91269572 |
23 | MP0008961_abnormal_basal_metabolism | 1.91246137 |
24 | MP0004233_abnormal_muscle_weight | 1.87836566 |
25 | MP0004197_abnormal_fetal_growth/weight/ | 1.86001202 |
26 | MP0003119_abnormal_digestive_system | 1.85943339 |
27 | MP0005623_abnormal_meninges_morphology | 1.85775895 |
28 | MP0000350_abnormal_cell_proliferation | 1.84995415 |
29 | MP0002653_abnormal_ependyma_morphology | 1.84339953 |
30 | MP0005187_abnormal_penis_morphology | 1.81776658 |
31 | MP0003121_genomic_imprinting | 1.80442396 |
32 | MP0005409_darkened_coat_color | 1.79314363 |
33 | MP0004858_abnormal_nervous_system | 1.78186796 |
34 | MP0009053_abnormal_anal_canal | 1.76765297 |
35 | MP0002085_abnormal_embryonic_tissue | 1.74206465 |
36 | MP0003077_abnormal_cell_cycle | 1.72077169 |
37 | MP0001697_abnormal_embryo_size | 1.68438951 |
38 | MP0001346_abnormal_lacrimal_gland | 1.66963741 |
39 | MP0008260_abnormal_autophagy | 1.66371701 |
40 | MP0000733_abnormal_muscle_development | 1.65832132 |
41 | MP0005380_embryogenesis_phenotype | 1.64840264 |
42 | MP0001672_abnormal_embryogenesis/_devel | 1.64840264 |
43 | MP0000751_myopathy | 1.64783027 |
44 | MP0010094_abnormal_chromosome_stability | 1.64443894 |
45 | MP0003122_maternal_imprinting | 1.64323914 |
46 | MP0002088_abnormal_embryonic_growth/wei | 1.60420456 |
47 | MP0003984_embryonic_growth_retardation | 1.59864400 |
48 | MP0000678_abnormal_parathyroid_gland | 1.59847630 |
49 | MP0002796_impaired_skin_barrier | 1.57433327 |
50 | MP0010307_abnormal_tumor_latency | 1.51205204 |
51 | MP0002080_prenatal_lethality | 1.50872103 |
52 | MP0003115_abnormal_respiratory_system | 1.50691027 |
53 | MP0002086_abnormal_extraembryonic_tissu | 1.50254865 |
54 | MP0003861_abnormal_nervous_system | 1.50001040 |
55 | MP0003566_abnormal_cell_adhesion | 1.48592039 |
56 | MP0000428_abnormal_craniofacial_morphol | 1.47181678 |
57 | MP0002877_abnormal_melanocyte_morpholog | 1.47053515 |
58 | MP0002089_abnormal_postnatal_growth/wei | 1.46618517 |
59 | MP0003693_abnormal_embryo_hatching | 1.44132651 |
60 | MP0005058_abnormal_lysosome_morphology | 1.43316892 |
61 | MP0003890_abnormal_embryonic-extraembry | 1.42582674 |
62 | MP0003300_gastrointestinal_ulcer | 1.42520385 |
63 | MP0005501_abnormal_skin_physiology | 1.41633799 |
64 | MP0001348_abnormal_lacrimal_gland | 1.33621263 |
65 | MP0000762_abnormal_tongue_morphology | 1.31526540 |
66 | MP0003567_abnormal_fetal_cardiomyocyte | 1.31127878 |
67 | MP0000534_abnormal_ureter_morphology | 1.29767179 |
68 | MP0009278_abnormal_bone_marrow | 1.27992206 |
69 | MP0003091_abnormal_cell_migration | 1.26503314 |
70 | MP0000778_abnormal_nervous_system | 1.24651642 |
71 | MP0009672_abnormal_birth_weight | 1.23607091 |
72 | MP0003453_abnormal_keratinocyte_physiol | 1.22022099 |
73 | MP0004811_abnormal_neuron_physiology | 1.19882404 |
74 | MP0002909_abnormal_adrenal_gland | 1.18140710 |
75 | MP0004185_abnormal_adipocyte_glucose | 1.17154190 |
76 | MP0001299_abnormal_eye_distance/ | 1.17057710 |
77 | MP0003385_abnormal_body_wall | 1.15857135 |
78 | MP0008932_abnormal_embryonic_tissue | 1.15744514 |
79 | MP0002060_abnormal_skin_morphology | 1.15520955 |
80 | MP0008007_abnormal_cellular_replicative | 1.13560786 |
81 | MP0000462_abnormal_digestive_system | 1.12298684 |
82 | MP0002098_abnormal_vibrissa_morphology | 1.11859595 |
83 | MP0003303_peritoneal_inflammation | 1.11329823 |
84 | MP0000467_abnormal_esophagus_morphology | 1.11313273 |
85 | MP0003935_abnormal_craniofacial_develop | 1.11299388 |
86 | MP0008770_decreased_survivor_rate | 1.10804891 |
87 | MP0002234_abnormal_pharynx_morphology | 1.09368383 |
88 | MP0004264_abnormal_extraembryonic_tissu | 1.08989021 |
89 | MP0002925_abnormal_cardiovascular_devel | 1.06585592 |
90 | MP0003942_abnormal_urinary_system | 1.05295602 |
91 | MP0002697_abnormal_eye_size | 1.01562449 |
92 | MP0009703_decreased_birth_body | 0.99883558 |
93 | MP0002822_catalepsy | 0.99838792 |
94 | MP0010630_abnormal_cardiac_muscle | 0.97081733 |
95 | MP0002184_abnormal_innervation | 0.96768607 |
96 | MP0005666_abnormal_adipose_tissue | 0.95839508 |
97 | MP0006054_spinal_hemorrhage | 0.95419768 |
98 | MP0000759_abnormal_skeletal_muscle | 0.95358170 |
99 | MP0003221_abnormal_cardiomyocyte_apopto | 0.94147332 |
100 | MP0001915_intracranial_hemorrhage | 0.93994096 |
101 | MP0002081_perinatal_lethality | 0.93685286 |
102 | MP0005248_abnormal_Harderian_gland | 0.93187684 |
103 | MP0002152_abnormal_brain_morphology | 0.93013099 |
104 | MP0000003_abnormal_adipose_tissue | 0.92817958 |
105 | MP0005394_taste/olfaction_phenotype | 0.91740456 |
106 | MP0005499_abnormal_olfactory_system | 0.91740456 |
107 | MP0009780_abnormal_chondrocyte_physiolo | 0.90509940 |
108 | MP0002092_abnormal_eye_morphology | 0.90425001 |
109 | MP0000747_muscle_weakness | 0.89794622 |
110 | MP0005508_abnormal_skeleton_morphology | 0.89119560 |
111 | MP0002896_abnormal_bone_mineralization | 0.88821044 |
112 | MP0000955_abnormal_spinal_cord | 0.87620868 |
113 | MP0008789_abnormal_olfactory_epithelium | 0.87345694 |
114 | MP0003634_abnormal_glial_cell | 0.87085267 |
115 | MP0001661_extended_life_span | 0.86738060 |
116 | MP0004808_abnormal_hematopoietic_stem | 0.85732028 |
117 | MP0002114_abnormal_axial_skeleton | 0.85295801 |
118 | MP0000750_abnormal_muscle_regeneration | 0.84793312 |
119 | MP0003279_aneurysm | 0.84670673 |
120 | MP0004084_abnormal_cardiac_muscle | 0.83970063 |
121 | MP0000377_abnormal_hair_follicle | 0.80953611 |
122 | MP0009384_cardiac_valve_regurgitation | 0.80607172 |
123 | MP0003329_amyloid_beta_deposits | 0.80475664 |
124 | MP0000432_abnormal_head_morphology | 0.79869687 |
125 | MP0005023_abnormal_wound_healing | 0.78962847 |
126 | MP0000266_abnormal_heart_morphology | 0.78861814 |
127 | MP0003315_abnormal_perineum_morphology | 0.78194671 |
128 | MP0001293_anophthalmia | 0.77730833 |
129 | MP0002396_abnormal_hematopoietic_system | 0.77242148 |
130 | MP0002111_abnormal_tail_morphology | 0.76119101 |
131 | MP0003937_abnormal_limbs/digits/tail_de | 0.76021641 |
132 | MP0003755_abnormal_palate_morphology | 0.75570547 |
133 | MP0002116_abnormal_craniofacial_bone | 0.73950783 |
134 | MP0002932_abnormal_joint_morphology | 0.70871600 |
135 | MP0005375_adipose_tissue_phenotype | 0.69853232 |
136 | MP0005621_abnormal_cell_physiology | 0.68518423 |
137 | MP0004087_abnormal_muscle_fiber | 0.68360584 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Hyperacusis (HP:0010780) | 3.72494285 |
2 | Premature rupture of membranes (HP:0001788) | 3.52944411 |
3 | Ependymoma (HP:0002888) | 3.33175693 |
4 | Astrocytoma (HP:0009592) | 3.28768271 |
5 | Abnormality of the astrocytes (HP:0100707) | 3.28768271 |
6 | Short 4th metacarpal (HP:0010044) | 3.27355590 |
7 | Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042) | 3.27355590 |
8 | Ulnar bowing (HP:0003031) | 2.98894921 |
9 | Broad face (HP:0000283) | 2.96283196 |
10 | Shallow orbits (HP:0000586) | 2.89231355 |
11 | Abnormality of the lower motor neuron (HP:0002366) | 2.86831398 |
12 | Renal duplication (HP:0000075) | 2.85077265 |
13 | Insomnia (HP:0100785) | 2.83965426 |
14 | Distal lower limb amyotrophy (HP:0008944) | 2.77338753 |
15 | Pointed chin (HP:0000307) | 2.69845866 |
16 | Amyotrophic lateral sclerosis (HP:0007354) | 2.64381441 |
17 | Abnormality of the 4th metacarpal (HP:0010012) | 2.58376253 |
18 | Bowel diverticulosis (HP:0005222) | 2.56380451 |
19 | Hand muscle atrophy (HP:0009130) | 2.55862402 |
20 | Cerebral aneurysm (HP:0004944) | 2.54510819 |
21 | Increased nuchal translucency (HP:0010880) | 2.54142139 |
22 | Elfin facies (HP:0004428) | 2.53862734 |
23 | Heterotopia (HP:0002282) | 2.53800887 |
24 | Flat acetabular roof (HP:0003180) | 2.50375156 |
25 | Shoulder girdle muscle weakness (HP:0003547) | 2.48543692 |
26 | Overriding aorta (HP:0002623) | 2.47666403 |
27 | Pelvic girdle muscle weakness (HP:0003749) | 2.47057287 |
28 | Broad distal phalanx of finger (HP:0009836) | 2.44750917 |
29 | Neoplasm of the heart (HP:0100544) | 2.44694477 |
30 | Cortical dysplasia (HP:0002539) | 2.43621669 |
31 | Renovascular hypertension (HP:0100817) | 2.41384021 |
32 | Abnormality of the distal phalanx of the thumb (HP:0009617) | 2.40066709 |
33 | Protrusio acetabuli (HP:0003179) | 2.37351034 |
34 | Short nail (HP:0001799) | 2.37187222 |
35 | Macroorchidism (HP:0000053) | 2.36555313 |
36 | Glioma (HP:0009733) | 2.34041592 |
37 | Disproportionate tall stature (HP:0001519) | 2.33509003 |
38 | Upper limb amyotrophy (HP:0009129) | 2.30541573 |
39 | Distal upper limb amyotrophy (HP:0007149) | 2.30541573 |
40 | Cervical subluxation (HP:0003308) | 2.28574472 |
41 | Lower limb amyotrophy (HP:0007210) | 2.27916674 |
42 | Increased density of long bones (HP:0006392) | 2.23182052 |
43 | Trigonocephaly (HP:0000243) | 2.22860600 |
44 | Genu recurvatum (HP:0002816) | 2.21549792 |
45 | Vertebral compression fractures (HP:0002953) | 2.18539826 |
46 | Wrist flexion contracture (HP:0001239) | 2.18000162 |
47 | Spinal rigidity (HP:0003306) | 2.17706333 |
48 | Fibroma (HP:0010614) | 2.17697481 |
49 | Lymphangioma (HP:0100764) | 2.16580165 |
50 | Obstructive sleep apnea (HP:0002870) | 2.16443734 |
51 | Turricephaly (HP:0000262) | 2.14993916 |
52 | Abnormality of dentin (HP:0010299) | 2.14771363 |
53 | Abnormality of the labia minora (HP:0012880) | 2.14164530 |
54 | Arnold-Chiari malformation (HP:0002308) | 2.13322645 |
55 | Insidious onset (HP:0003587) | 2.12240651 |
56 | Termporal pattern (HP:0011008) | 2.12240651 |
57 | Adenoma sebaceum (HP:0009720) | 2.11193960 |
58 | Angiofibromas (HP:0010615) | 2.11193960 |
59 | Patellar dislocation (HP:0002999) | 2.11163311 |
60 | Subacute progressive viral hepatitis (HP:0006572) | 2.10672434 |
61 | Abnormality of the musculature of the pelvis (HP:0001469) | 2.09523135 |
62 | Abnormality of the hip-girdle musculature (HP:0001445) | 2.09523135 |
63 | Fibrous tissue neoplasm (HP:0012316) | 2.09073604 |
64 | Increased connective tissue (HP:0009025) | 2.08393833 |
65 | Sacral dimple (HP:0000960) | 2.08138836 |
66 | Centrally nucleated skeletal muscle fibers (HP:0003687) | 2.05331929 |
67 | Enlarged penis (HP:0000040) | 2.04741787 |
68 | High anterior hairline (HP:0009890) | 2.03964894 |
69 | Deep palmar crease (HP:0006191) | 2.03750400 |
70 | Mitral regurgitation (HP:0001653) | 2.03326543 |
71 | Ankle contracture (HP:0006466) | 2.03053798 |
72 | Megalocornea (HP:0000485) | 2.02747357 |
73 | Apathy (HP:0000741) | 2.02061943 |
74 | Bladder diverticulum (HP:0000015) | 2.02041104 |
75 | Fragile skin (HP:0001030) | 1.96841740 |
76 | Abnormality of the distal phalanges of the toes (HP:0010182) | 1.96162681 |
77 | Diminished motivation (HP:0000745) | 1.95775586 |
78 | Hallux valgus (HP:0001822) | 1.93936170 |
79 | Asymmetry of the thorax (HP:0001555) | 1.92842763 |
80 | Deviation of the hallux (HP:0010051) | 1.91743564 |
81 | Bronchomalacia (HP:0002780) | 1.91181952 |
82 | Advanced eruption of teeth (HP:0006288) | 1.90559671 |
83 | Premature skin wrinkling (HP:0100678) | 1.90389430 |
84 | Flat cornea (HP:0007720) | 1.90127015 |
85 | Broad palm (HP:0001169) | 1.88391078 |
86 | Atrophic scars (HP:0001075) | 1.87837532 |
87 | Overlapping toe (HP:0001845) | 1.86990649 |
88 | Mildly elevated creatine phosphokinase (HP:0008180) | 1.86472514 |
89 | Colon cancer (HP:0003003) | 1.85881824 |
90 | Achilles tendon contracture (HP:0001771) | 1.85858444 |
91 | Thin bony cortex (HP:0002753) | 1.84565107 |
92 | Back pain (HP:0003418) | 1.83724590 |
93 | Hammertoe (HP:0001765) | 1.80879327 |
94 | Increased variability in muscle fiber diameter (HP:0003557) | 1.80536453 |
95 | Cholecystitis (HP:0001082) | 1.80416736 |
96 | Abnormal gallbladder physiology (HP:0012438) | 1.80416736 |
97 | Gastrointestinal carcinoma (HP:0002672) | 1.79918098 |
98 | Malignant gastrointestinal tract tumors (HP:0006749) | 1.79918098 |
99 | Metaphyseal cupping (HP:0003021) | 1.79596784 |
100 | Trismus (HP:0000211) | 1.79512003 |
101 | Ankyloglossia (HP:0010296) | 1.78689932 |
102 | Abnormality of oral frenula (HP:0000190) | 1.78637785 |
103 | Selective tooth agenesis (HP:0001592) | 1.78595999 |
104 | Intellectual disability, profound (HP:0002187) | 1.77889354 |
105 | Dilatation of the ascending aorta (HP:0005111) | 1.77171479 |
106 | Aneurysm (HP:0002617) | 1.76800361 |
107 | Flattened epiphyses (HP:0003071) | 1.75996930 |
108 | Natal tooth (HP:0000695) | 1.75910805 |
109 | Medulloblastoma (HP:0002885) | 1.75612317 |
110 | Abnormality of the calcaneus (HP:0008364) | 1.75524371 |
111 | Biconcave vertebral bodies (HP:0004586) | 1.74138683 |
112 | Wormian bones (HP:0002645) | 1.73295186 |
113 | Abnormality of the phalanges of the hallux (HP:0010057) | 1.73216009 |
114 | Obsessive-compulsive behavior (HP:0000722) | 1.73007403 |
115 | Limb-girdle muscle atrophy (HP:0003797) | 1.71200178 |
116 | Pseudobulbar signs (HP:0002200) | 1.69783722 |
117 | Thin ribs (HP:0000883) | 1.69442063 |
118 | Congenital glaucoma (HP:0001087) | 1.68905586 |
119 | Blue sclerae (HP:0000592) | 1.68848115 |
120 | Distal lower limb muscle weakness (HP:0009053) | 1.68227793 |
121 | Neoplasm of striated muscle (HP:0009728) | 1.68185663 |
122 | Mitral valve prolapse (HP:0001634) | 1.67926210 |
123 | Dysmetric saccades (HP:0000641) | 1.67042189 |
124 | Facial hemangioma (HP:0000329) | 1.66784277 |
125 | Cerebral inclusion bodies (HP:0100314) | 1.66522041 |
126 | Abnormal ossification of hand bones (HP:0005921) | 1.65772161 |
127 | Vertebral arch anomaly (HP:0008438) | 1.65560383 |
128 | Broad thumb (HP:0011304) | 1.64889147 |
129 | Hyperparathyroidism (HP:0000843) | 1.63376005 |
130 | Urinary urgency (HP:0000012) | 1.63105196 |
131 | Long palpebral fissure (HP:0000637) | 1.62655247 |
132 | Hereditary nonpolyposis colorectal carcinoma (HP:0006716) | 1.62532021 |
133 | Generalized hypotonia (HP:0001290) | 1.61762000 |
134 | Sparse lateral eyebrow (HP:0005338) | 1.61296348 |
135 | Joint laxity (HP:0001388) | 1.61240935 |
136 | Rectal prolapse (HP:0002035) | 1.60836743 |
137 | Intestinal polyp (HP:0005266) | 1.60819139 |
138 | Neoplasm of the oral cavity (HP:0100649) | 1.60768948 |
139 | Broad metatarsal (HP:0001783) | 1.60410617 |
140 | Relative macrocephaly (HP:0004482) | 1.60141205 |
141 | Leiomyosarcoma (HP:0100243) | 1.59831960 |
142 | Uterine leiomyosarcoma (HP:0002891) | 1.59831960 |
143 | Abnormality of the aortic arch (HP:0012303) | 1.59426154 |
144 | Hepatoblastoma (HP:0002884) | 1.59266819 |
145 | Abnormality of the diencephalon (HP:0010662) | 1.59194541 |
146 | Difficulty climbing stairs (HP:0003551) | 1.58955524 |
147 | Spina bifida occulta (HP:0003298) | 1.58896240 |
148 | Long eyelashes (HP:0000527) | 1.58566892 |
149 | Midface retrusion (HP:0011800) | 1.58389155 |
150 | Annular pancreas (HP:0001734) | 1.57698510 |
151 | Rhizomelia (HP:0008905) | 1.57435407 |
152 | * Deviation of the thumb (HP:0009603) | 1.57259515 |
153 | Exostoses (HP:0100777) | 1.56780857 |
154 | Cutis marmorata (HP:0000965) | 1.56655379 |
155 | Abnormality of the Achilles tendon (HP:0005109) | 1.56589563 |
156 | Aplasia involving bones of the upper limbs (HP:0009823) | 1.55318359 |
157 | Aplasia of the phalanges of the hand (HP:0009802) | 1.55318359 |
158 | Aplasia involving bones of the extremities (HP:0009825) | 1.55318359 |
159 | Missing ribs (HP:0000921) | 1.55201678 |
160 | Precocious puberty (HP:0000826) | 1.55108772 |
161 | Attention deficit hyperactivity disorder (HP:0007018) | 1.55036749 |
162 | Basal cell carcinoma (HP:0002671) | 1.54559165 |
Rank | Gene Set | Z-score |
---|---|---|
1 | TRIB3 | 3.99693536 |
2 | EEF2K | 3.98295467 |
3 | SMG1 | 3.88368009 |
4 | PKN2 | 3.46153138 |
5 | CDK12 | 2.89964130 |
6 | MAP3K10 | 2.63203179 |
7 | PRPF4B | 2.61747039 |
8 | MARK1 | 2.58695420 |
9 | SCYL2 | 2.30884120 |
10 | NEK1 | 2.23724303 |
11 | MAP3K9 | 2.10593122 |
12 | LATS2 | 2.01950439 |
13 | KSR1 | 1.97198032 |
14 | ALK | 1.95826388 |
15 | PDGFRA | 1.92137730 |
16 | CDC7 | 1.87751795 |
17 | IRAK3 | 1.85149726 |
18 | ICK | 1.60166077 |
19 | TYRO3 | 1.59013197 |
20 | TSSK6 | 1.57367300 |
21 | TTN | 1.52347794 |
22 | TESK2 | 1.52185169 |
23 | KSR2 | 1.48751996 |
24 | PAK6 | 1.45475678 |
25 | PASK | 1.43172059 |
26 | RIPK1 | 1.42687776 |
27 | PTK6 | 1.40362137 |
28 | LMTK2 | 1.40147332 |
29 | NEK2 | 1.39812846 |
30 | MTOR | 1.31836287 |
31 | MINK1 | 1.30452229 |
32 | MST1R | 1.22902637 |
33 | EPHB1 | 1.21952904 |
34 | NME2 | 1.20453652 |
35 | RET | 1.17807716 |
36 | PRKD3 | 1.15394933 |
37 | FGFR1 | 1.13123309 |
38 | PAK4 | 1.12941240 |
39 | TAOK2 | 1.07098445 |
40 | ARAF | 1.05114849 |
41 | TESK1 | 1.04870413 |
42 | RPS6KB2 | 1.04862389 |
43 | EPHB2 | 1.04542844 |
44 | PAK2 | 1.02083977 |
45 | LIMK1 | 1.00943242 |
46 | TGFBR1 | 0.99896920 |
47 | TAOK1 | 0.99250057 |
48 | BRD4 | 0.92860331 |
49 | LRRK2 | 0.89463845 |
50 | SIK2 | 0.89384674 |
51 | MET | 0.86802802 |
52 | CDK6 | 0.85172855 |
53 | NTRK2 | 0.85091223 |
54 | FER | 0.84153394 |
55 | MAP3K8 | 0.83751979 |
56 | FGFR4 | 0.82591756 |
57 | PTK2 | 0.81519833 |
58 | PRKD2 | 0.79623962 |
59 | UHMK1 | 0.79607125 |
60 | PAK3 | 0.77842677 |
61 | EIF2AK1 | 0.77544955 |
62 | CDK14 | 0.76441596 |
63 | CDK4 | 0.75588221 |
64 | DDR2 | 0.73807822 |
65 | SIK1 | 0.73245797 |
66 | CDK18 | 0.73154812 |
67 | CDK15 | 0.73071368 |
68 | CHEK1 | 0.72493598 |
69 | BMX | 0.71049666 |
70 | DYRK2 | 0.70665677 |
71 | FGFR3 | 0.69448297 |
72 | PNCK | 0.69240806 |
73 | BRAF | 0.67595370 |
74 | LATS1 | 0.67398490 |
75 | MAP3K4 | 0.66734289 |
76 | CDK11A | 0.66261952 |
77 | CAMKK1 | 0.65551824 |
78 | ERBB2 | 0.65523153 |
79 | CDK2 | 0.64845660 |
80 | FGFR2 | 0.64508441 |
81 | CAMK1G | 0.64360709 |
82 | EPHA3 | 0.64269209 |
83 | PDGFRB | 0.63912301 |
84 | EPHA2 | 0.63500718 |
85 | MAP3K6 | 0.62778791 |
86 | PLK3 | 0.62197654 |
87 | NTRK1 | 0.60625600 |
88 | CSNK1E | 0.59106411 |
89 | ATR | 0.58881430 |
90 | CAMK1D | 0.56726041 |
91 | AURKA | 0.56691499 |
92 | ILK | 0.55979152 |
93 | BRSK1 | 0.55401119 |
94 | CDK9 | 0.55320827 |
95 | TTK | 0.55215775 |
96 | DYRK1B | 0.53153453 |
97 | BUB1 | 0.52663173 |
98 | RPS6KA2 | 0.51880396 |
99 | RPS6KC1 | 0.50106121 |
100 | RPS6KL1 | 0.50106121 |
101 | CDK7 | 0.48255066 |
102 | STK10 | 0.47948605 |
103 | CSNK1G2 | 0.47666594 |
104 | MAPK9 | 0.47311079 |
105 | MAP2K3 | 0.47215577 |
106 | PDPK1 | 0.46309194 |
107 | ERN1 | 0.45742143 |
108 | DMPK | 0.45432646 |
109 | CSNK1D | 0.45368319 |
110 | PLK1 | 0.45245550 |
111 | MAP3K11 | 0.45007862 |
112 | MAP2K2 | 0.44876516 |
113 | * CDK1 | 0.44847073 |
114 | PIM2 | 0.44439496 |
115 | CDC42BPA | 0.44231343 |
116 | VRK2 | 0.43992731 |
117 | SIK3 | 0.43874602 |
118 | MARK2 | 0.42927994 |
119 | WEE1 | 0.41748739 |
120 | IRAK2 | 0.41564376 |
121 | MAP3K2 | 0.41290764 |
122 | PAK1 | 0.40067665 |
123 | PRKDC | 0.39717843 |
124 | CSNK1A1L | 0.39276596 |
125 | CHEK2 | 0.38761664 |
126 | AKT2 | 0.38712382 |
127 | MAP3K13 | 0.38481899 |
128 | MAP3K1 | 0.36125179 |
129 | MAPK11 | 0.34863308 |
130 | SRPK1 | 0.32044335 |
131 | MAPK10 | 0.31949236 |
132 | MOS | 0.31488775 |
133 | STK38 | 0.30482529 |
134 | ROCK2 | 0.28833455 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 2.01382078 |
2 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 1.90953484 |
3 | mTOR signaling pathway_Homo sapiens_hsa04150 | 1.86500449 |
4 | RNA transport_Homo sapiens_hsa03013 | 1.84839535 |
5 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 1.84836850 |
6 | Colorectal cancer_Homo sapiens_hsa05210 | 1.81455645 |
7 | Endometrial cancer_Homo sapiens_hsa05213 | 1.78834659 |
8 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 1.73610990 |
9 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.67695994 |
10 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 1.66365278 |
11 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 1.64142965 |
12 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 1.62473095 |
13 | Glioma_Homo sapiens_hsa05214 | 1.58831698 |
14 | Hippo signaling pathway_Homo sapiens_hsa04390 | 1.56000486 |
15 | Cell cycle_Homo sapiens_hsa04110 | 1.55782760 |
16 | Oocyte meiosis_Homo sapiens_hsa04114 | 1.52332523 |
17 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 1.49953654 |
18 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 1.47455563 |
19 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 1.45731260 |
20 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 1.45706279 |
21 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 1.43805401 |
22 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 1.43452917 |
23 | Spliceosome_Homo sapiens_hsa03040 | 1.42986301 |
24 | Viral myocarditis_Homo sapiens_hsa05416 | 1.42625069 |
25 | Prion diseases_Homo sapiens_hsa05020 | 1.39107242 |
26 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 1.38403452 |
27 | Adherens junction_Homo sapiens_hsa04520 | 1.37031559 |
28 | Bladder cancer_Homo sapiens_hsa05219 | 1.33500617 |
29 | VEGF signaling pathway_Homo sapiens_hsa04370 | 1.33115236 |
30 | Renal cell carcinoma_Homo sapiens_hsa05211 | 1.32892488 |
31 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 1.32657195 |
32 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 1.30805364 |
33 | * Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 1.30175446 |
34 | Basal cell carcinoma_Homo sapiens_hsa05217 | 1.30152672 |
35 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 1.27694085 |
36 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 1.27419286 |
37 | Notch signaling pathway_Homo sapiens_hsa04330 | 1.27171424 |
38 | Thyroid cancer_Homo sapiens_hsa05216 | 1.24579999 |
39 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 1.24125009 |
40 | Galactose metabolism_Homo sapiens_hsa00052 | 1.20591838 |
41 | Pancreatic cancer_Homo sapiens_hsa05212 | 1.18046713 |
42 | DNA replication_Homo sapiens_hsa03030 | 1.16499054 |
43 | Carbon metabolism_Homo sapiens_hsa01200 | 1.16332361 |
44 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.16100950 |
45 | Other glycan degradation_Homo sapiens_hsa00511 | 1.14318739 |
46 | Gap junction_Homo sapiens_hsa04540 | 1.13570485 |
47 | Axon guidance_Homo sapiens_hsa04360 | 1.12591854 |
48 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 1.11170249 |
49 | HTLV-I infection_Homo sapiens_hsa05166 | 1.10364306 |
50 | Viral carcinogenesis_Homo sapiens_hsa05203 | 1.05468815 |
51 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 1.05350336 |
52 | ErbB signaling pathway_Homo sapiens_hsa04012 | 1.04384610 |
53 | Focal adhesion_Homo sapiens_hsa04510 | 1.04340994 |
54 | Insulin signaling pathway_Homo sapiens_hsa04910 | 1.03526629 |
55 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 1.03494841 |
56 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 1.01067741 |
57 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.98395250 |
58 | ECM-receptor interaction_Homo sapiens_hsa04512 | 0.97283184 |
59 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.95719098 |
60 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.95042465 |
61 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 0.92678977 |
62 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 0.92578445 |
63 | Tight junction_Homo sapiens_hsa04530 | 0.90926067 |
64 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.89628427 |
65 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.89533700 |
66 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.89516063 |
67 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.89230280 |
68 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.89088738 |
69 | Long-term potentiation_Homo sapiens_hsa04720 | 0.88301600 |
70 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.88125578 |
71 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.87699878 |
72 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.87410125 |
73 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.87176791 |
74 | Lysine degradation_Homo sapiens_hsa00310 | 0.86831183 |
75 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.85631962 |
76 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.84822219 |
77 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.84489265 |
78 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.83953936 |
79 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.82139219 |
80 | Endocytosis_Homo sapiens_hsa04144 | 0.81950649 |
81 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.81510489 |
82 | Amoebiasis_Homo sapiens_hsa05146 | 0.79866488 |
83 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.79356472 |
84 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.77932714 |
85 | Shigellosis_Homo sapiens_hsa05131 | 0.76634153 |
86 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 0.76309350 |
87 | Melanogenesis_Homo sapiens_hsa04916 | 0.75793736 |
88 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 0.73577050 |
89 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.72591891 |
90 | Prostate cancer_Homo sapiens_hsa05215 | 0.72459321 |
91 | Pathways in cancer_Homo sapiens_hsa05200 | 0.72125132 |
92 | Insulin resistance_Homo sapiens_hsa04931 | 0.71526426 |
93 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.71100974 |
94 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.71061751 |
95 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 0.71052470 |
96 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.70374472 |
97 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.70280580 |
98 | Mismatch repair_Homo sapiens_hsa03430 | 0.69689471 |
99 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.69601326 |
100 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.69434136 |
101 | Sulfur relay system_Homo sapiens_hsa04122 | 0.69303150 |
102 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.68627202 |
103 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.67839008 |
104 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.67606387 |
105 | Hepatitis B_Homo sapiens_hsa05161 | 0.66027539 |
106 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 0.65807665 |
107 | Apoptosis_Homo sapiens_hsa04210 | 0.65721406 |
108 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.64666270 |
109 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.63276795 |
110 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.62616152 |
111 | Base excision repair_Homo sapiens_hsa03410 | 0.62387266 |
112 | Salmonella infection_Homo sapiens_hsa05132 | 0.61307732 |
113 | Hepatitis C_Homo sapiens_hsa05160 | 0.61266543 |
114 | Melanoma_Homo sapiens_hsa05218 | 0.60647748 |
115 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.60420472 |
116 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.60217640 |
117 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.59769971 |
118 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.59688328 |
119 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.58399619 |
120 | Alcoholism_Homo sapiens_hsa05034 | 0.58335982 |
121 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.58252224 |
122 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.57307698 |
123 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.57283285 |
124 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.56804304 |
125 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.56221415 |