UBA52P5

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1mature B cell differentiation involved in immune response (GO:0002313)9.75160425
2female mating behavior (GO:0060180)9.17309054
3skeletal muscle tissue regeneration (GO:0043403)8.45277866
4phospholipase C-activating dopamine receptor signaling pathway (GO:0060158)8.27997404
5negative regulation of hematopoietic progenitor cell differentiation (GO:1901533)7.41104821
6mature B cell differentiation (GO:0002335)7.13163219
7positive regulation of inositol phosphate biosynthetic process (GO:0060732)7.00527640
8synaptic transmission, dopaminergic (GO:0001963)6.49696721
9adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191)6.37742061
10protein targeting to vacuole (GO:0006623)6.31845409
11protein targeting to lysosome (GO:0006622)6.31845409
12establishment of protein localization to vacuole (GO:0072666)6.31845409
13lipoxygenase pathway (GO:0019372)6.10234625
14cellular glucuronidation (GO:0052695)6.04332369
15detection of light stimulus involved in sensory perception (GO:0050962)5.90124321
16detection of light stimulus involved in visual perception (GO:0050908)5.90124321
17polarized epithelial cell differentiation (GO:0030859)5.87122582
18pantothenate metabolic process (GO:0015939)5.66770236
19embryonic heart tube development (GO:0035050)5.66275058
20glucuronate metabolic process (GO:0019585)5.61360855
21uronic acid metabolic process (GO:0006063)5.61360855
22positive regulation of cAMP-mediated signaling (GO:0043950)5.60567401
23regulation of inositol phosphate biosynthetic process (GO:0010919)5.59068476
24morphogenesis of an endothelium (GO:0003159)5.48018963
25endothelial tube morphogenesis (GO:0061154)5.48018963
26coenzyme catabolic process (GO:0009109)5.44635030
27negative regulation of oxidoreductase activity (GO:0051354)5.27923538
28long term synaptic depression (GO:0060292)5.12179989
29glycosphingolipid biosynthetic process (GO:0006688)5.08098142
30regulation of sensory perception (GO:0051931)4.93456524
31regulation of sensory perception of pain (GO:0051930)4.93456524
32protein localization to lysosome (GO:0061462)4.83361521
33protein localization to vacuole (GO:0072665)4.83361521
34lymphangiogenesis (GO:0001946)4.73351897
35regulation of antigen processing and presentation of peptide antigen (GO:0002583)4.72932686
36regulation of MHC class II biosynthetic process (GO:0045346)4.65516232
37collecting duct development (GO:0072044)4.47880696
38regulation of macrophage chemotaxis (GO:0010758)4.25808711
39positive regulation of chemokine secretion (GO:0090197)4.18646989
40GTP biosynthetic process (GO:0006183)4.17446672
41neuronal action potential (GO:0019228)4.07966846
42apical protein localization (GO:0045176)4.05108044
43transmission of nerve impulse (GO:0019226)4.03531790
44pericardium development (GO:0060039)3.97650510
45regulation of calcineurin-NFAT signaling cascade (GO:0070884)3.93371297
46DNA deamination (GO:0045006)3.87136797
47positive regulation of macrophage derived foam cell differentiation (GO:0010744)3.85096154
48nonmotile primary cilium assembly (GO:0035058)3.79658156
49positive regulation of macrophage differentiation (GO:0045651)3.77693688
50positive regulation of calcium-mediated signaling (GO:0050850)3.77189646
51receptor guanylyl cyclase signaling pathway (GO:0007168)3.73740096
52glycosylceramide metabolic process (GO:0006677)3.71140619
53UTP biosynthetic process (GO:0006228)3.69762091
54venous blood vessel morphogenesis (GO:0048845)3.67138842
55basic amino acid transport (GO:0015802)3.66503080
56primary amino compound metabolic process (GO:1901160)3.61243871
57regulation of chemokine secretion (GO:0090196)3.58113454
58multicellular organismal reproductive behavior (GO:0033057)3.56250404
59leukocyte tethering or rolling (GO:0050901)3.53929432
60endothelial cell development (GO:0001885)3.50745977
61regulation of germinal center formation (GO:0002634)3.40334280
62activation of adenylate cyclase activity (GO:0007190)3.34520418
63positive regulation of interleukin-8 secretion (GO:2000484)3.31991788
64UTP metabolic process (GO:0046051)3.26329591
65ATP synthesis coupled proton transport (GO:0015986)3.21696648
66energy coupled proton transport, down electrochemical gradient (GO:0015985)3.21696648
67positive regulation of phosphatase activity (GO:0010922)3.21680954
68B cell activation involved in immune response (GO:0002312)3.19321385
69regulation of transcription from RNA polymerase I promoter (GO:0006356)3.08338876
70tissue regeneration (GO:0042246)3.06124436
71negative regulation of dendrite development (GO:2000171)3.01415622
72protein polyglutamylation (GO:0018095)3.00453853
73regulation of calcium-mediated signaling (GO:0050848)2.99306625
74positive regulation of adenylate cyclase activity (GO:0045762)2.95385489
75indolalkylamine metabolic process (GO:0006586)2.95298718
76protein localization to cilium (GO:0061512)2.94104010
77negative regulation of monooxygenase activity (GO:0032769)2.91518545
78positive regulation of T cell migration (GO:2000406)2.91421833
79fat-soluble vitamin biosynthetic process (GO:0042362)2.90725678
80positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)2.89144964
81cofactor catabolic process (GO:0051187)2.88911613
82purine ribonucleotide transport (GO:0015868)2.88794200
83detection of chemical stimulus involved in sensory perception of smell (GO:0050911)2.88117809
84response to amphetamine (GO:0001975)2.87493072
85serotonin metabolic process (GO:0042428)2.86649378
86regulation of megakaryocyte differentiation (GO:0045652)2.84027489
87regulation of systemic arterial blood pressure by hormone (GO:0001990)2.83517712
88regulation of systemic arterial blood pressure mediated by a chemical signal (GO:0003044)2.83517712
89endocrine process (GO:0050886)2.83517712
90regulation of cAMP-mediated signaling (GO:0043949)2.80673716
91endothelial cell differentiation (GO:0045446)2.80095361
92cellular response to catecholamine stimulus (GO:0071870)2.77684129
93cellular response to monoamine stimulus (GO:0071868)2.77684129
94sensory perception of smell (GO:0007608)2.77052885
95L-fucose catabolic process (GO:0042355)2.74024430
96fucose catabolic process (GO:0019317)2.74024430
97L-fucose metabolic process (GO:0042354)2.74024430
98fat-soluble vitamin catabolic process (GO:0042363)11.4945041
99vitamin catabolic process (GO:0009111)11.4945041
100regulation of female receptivity (GO:0045924)10.3922530

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1NR4A2_19515692_ChIP-ChIP_MN9D_Mouse5.17098115
2IRF8_22096565_ChIP-ChIP_GC-B_Human3.90441250
3LYL1_20887958_ChIP-Seq_HPC-7_Mouse3.28336662
4IRF1_21803131_ChIP-Seq_MONOCYTES_Human2.94504266
5EED_16625203_ChIP-ChIP_MESCs_Mouse2.89775288
6ZNF652_21678463_ChIP-ChIP_ZR75-1_Human2.81696396
7ESR1_20079471_ChIP-ChIP_T-47D_Human2.72738503
8KLF2_18264089_ChIP-ChIP_MESCs_Mouse2.64182783
9KLF5_18264089_ChIP-ChIP_MESCs_Mouse2.64182783
10KLF4_18264089_ChIP-ChIP_MESCs_Mouse2.64182783
11PPARG_19300518_ChIP-PET_3T3-L1_Mouse2.60818381
12THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse2.52507830
13GBX2_23144817_ChIP-Seq_PC3_Human2.52491746
14SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.39287449
15STAT6_20620947_ChIP-Seq_CD4_POS_T_Human2.24816120
16JARID2_20064375_ChIP-Seq_MESCs_Mouse2.24256780
17SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.92378830
18JARID2_20075857_ChIP-Seq_MESCs_Mouse1.92063236
19RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.86510528
20ZFP57_27257070_Chip-Seq_ESCs_Mouse1.86478368
21LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.86118688
22FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.85387211
23DROSHA_22980978_ChIP-Seq_HELA_Human1.85021271
24TDRD3_21172665_ChIP-Seq_MCF-7_Human1.84655437
25IKZF1_21737484_ChIP-ChIP_HCT116_Human1.82215590
26CTBP2_25329375_ChIP-Seq_LNCAP_Human1.79241132
27EZH2_22144423_ChIP-Seq_EOC_Human1.76816576
28RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.75925281
29EWS_26573619_Chip-Seq_HEK293_Human1.75792355
30SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.74664023
31AUTS2_25519132_ChIP-Seq_293T-REX_Human1.72444915
32CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.71529127
33SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.70566586
34ARNT_22903824_ChIP-Seq_MCF-7_Human1.69745545
35NCOR_22424771_ChIP-Seq_293T_Human1.67459733
36SMAD3_21741376_ChIP-Seq_EPCs_Human1.66692398
37SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.65874037
38BCAT_22108803_ChIP-Seq_LS180_Human1.59706119
39POU5F1_16153702_ChIP-ChIP_HESCs_Human1.59030811
40CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.54704276
41EZH2_18974828_ChIP-Seq_MESCs_Mouse1.54660449
42RNF2_18974828_ChIP-Seq_MESCs_Mouse1.54660449
43GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.52625308
44SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.47250222
45P53_21459846_ChIP-Seq_SAOS-2_Human1.42028148
46GATA2_20887958_ChIP-Seq_HPC-7_Mouse1.41838309
47BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.40980086
48CTBP1_25329375_ChIP-Seq_LNCAP_Human1.39470158
49IRF8_27001747_Chip-Seq_BMDM_Mouse1.32574288
50SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.30355945
51UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.30136566
52POU3F2_20337985_ChIP-ChIP_501MEL_Human1.27522734
53SOX2_21211035_ChIP-Seq_LN229_Human1.27475912
54BMI1_23680149_ChIP-Seq_NPCS_Mouse1.27156071
55STAT3_23295773_ChIP-Seq_U87_Human1.26534586
56OCT4_19829295_ChIP-Seq_ESCs_Human1.24413287
57TP53_20018659_ChIP-ChIP_R1E_Mouse1.22601582
58EZH2_27304074_Chip-Seq_ESCs_Mouse1.21413085
59REST_21632747_ChIP-Seq_MESCs_Mouse1.17342817
60EBNA1_20929547_Chip-Seq_RAJI-cells_Human1.15720599
61CBX2_27304074_Chip-Seq_ESCs_Mouse1.11879403
62TAF2_19829295_ChIP-Seq_ESCs_Human1.11796525
63CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.11056586
64PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.09973331
65RAD21_21589869_ChIP-Seq_MESCs_Mouse1.09484329
66RAC3_21632823_ChIP-Seq_H3396_Human1.09405853
67PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.09250834
68FLI1_21867929_ChIP-Seq_TH2_Mouse1.09072664
69CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.08789835
70POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.08564748
71TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.08564748
72FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.07573547
73RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.07193636
74PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse1.07118990
75SMAD4_21741376_ChIP-Seq_EPCs_Human1.06449164
76CTCF_20526341_ChIP-Seq_ESCs_Human1.06416974
77SUZ12_27294783_Chip-Seq_ESCs_Mouse1.04941423
78CBP_20019798_ChIP-Seq_JUKART_Human1.04559725
79IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.04559725
80YY1_21170310_ChIP-Seq_MESCs_Mouse1.04308050
81HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.04299641
82FOXH1_21741376_ChIP-Seq_ESCs_Human1.02475530
83SMAD4_21799915_ChIP-Seq_A2780_Human1.00198690
84IGF1R_20145208_ChIP-Seq_DFB_Human0.99600741
85SPI1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.99590622
86PPARD_23208498_ChIP-Seq_MDA-MB-231_Human0.99381426
87SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.98563368
88TP53_22573176_ChIP-Seq_HFKS_Human0.98268318
89AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.97756157
90FUS_26573619_Chip-Seq_HEK293_Human0.96382466
91P68_20966046_ChIP-Seq_HELA_Human0.96251632
92TCF4_23295773_ChIP-Seq_U87_Human0.96190080
93AHR_22903824_ChIP-Seq_MCF-7_Human0.95624879
94TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse0.95276502
95FLI1_27457419_Chip-Seq_LIVER_Mouse0.94460760
96OCT1_27270436_Chip-Seq_PROSTATE_Human0.93863095
97TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.91960362
98MTF2_20144788_ChIP-Seq_MESCs_Mouse0.91258747
99BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.89290570
100SUZ12_20075857_ChIP-Seq_MESCs_Mouse0.87037198

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002653_abnormal_ependyma_morphology9.84322670
2MP0002736_abnormal_nociception_after6.24218555
3MP0005409_darkened_coat_color5.39012457
4MP0005360_urolithiasis5.10589510
5MP0001968_abnormal_touch/_nociception4.76378923
6MP0003172_abnormal_lysosome_physiology4.16278916
7MP0009840_abnormal_foam_cell4.14234509
8MP0000678_abnormal_parathyroid_gland3.34927565
9MP0002909_abnormal_adrenal_gland3.28774095
10MP0006276_abnormal_autonomic_nervous3.17218147
11MP0009697_abnormal_copulation3.07812640
12MP0005083_abnormal_biliary_tract2.61379829
13MP0002734_abnormal_mechanical_nocicepti2.54465407
14MP0003724_increased_susceptibility_to1.96137408
15MP0002277_abnormal_respiratory_mucosa1.94496319
16MP0009053_abnormal_anal_canal1.67744940
17MP0002928_abnormal_bile_duct1.65332688
18MP0003646_muscle_fatigue1.57780239
19MP0005646_abnormal_pituitary_gland1.47626463
20MP0001879_abnormal_lymphatic_vessel1.45413976
21MP0002148_abnormal_hypersensitivity_rea1.40742318
22MP0008789_abnormal_olfactory_epithelium1.36502961
23MP0004742_abnormal_vestibular_system1.32898076
24MP0001873_stomach_inflammation1.32550961
25MP0001984_abnormal_olfaction1.31654815
26MP0001970_abnormal_pain_threshold1.27738194
27MP0006292_abnormal_olfactory_placode1.09801473
28MP0002933_joint_inflammation1.02894881
29MP0003136_yellow_coat_color1.01240986
30MP0000534_abnormal_ureter_morphology0.99228037
31MP0005499_abnormal_olfactory_system0.98174227
32MP0005394_taste/olfaction_phenotype0.98174227
33MP0005671_abnormal_response_to0.96674062
34MP0003718_maternal_effect0.93171471
35MP0002127_abnormal_cardiovascular_syste0.92345215
36MP0000537_abnormal_urethra_morphology0.92315716
37MP0000049_abnormal_middle_ear0.91744620
38MP0003119_abnormal_digestive_system0.90234685
39MP0002735_abnormal_chemical_nociception0.86318428
40MP0002138_abnormal_hepatobiliary_system0.83562885
41MP0000613_abnormal_salivary_gland0.83196379
42MP0002098_abnormal_vibrissa_morphology0.80662468
43MP0003879_abnormal_hair_cell0.79478908
44MP0002249_abnormal_larynx_morphology0.77814296
45MP0000516_abnormal_urinary_system0.77686305
46MP0005367_renal/urinary_system_phenotyp0.77686305
47MP0001502_abnormal_circadian_rhythm0.76783097
48MP0004381_abnormal_hair_follicle0.76478968
49MP0002282_abnormal_trachea_morphology0.74768873
50MP0003938_abnormal_ear_development0.72443455
51MP0000631_abnormal_neuroendocrine_gland0.72343287
52MP0002132_abnormal_respiratory_system0.71756904
53MP0004859_abnormal_synaptic_plasticity0.70461417
54MP0000538_abnormal_urinary_bladder0.69162893
55MP0003195_calcinosis0.69140677
56MP0002272_abnormal_nervous_system0.67288180
57MP0003950_abnormal_plasma_membrane0.67095280
58MP0004085_abnormal_heartbeat0.66655981
59MP0009250_abnormal_appendicular_skeleto0.63735540
60MP0004130_abnormal_muscle_cell0.63694046
61MP0008872_abnormal_physiological_respon0.62947731
62MP0003868_abnormal_feces_composition0.62656206
63MP0010771_integument_phenotype0.61326191
64MP0000230_abnormal_systemic_arterial0.60731135
65MP0006072_abnormal_retinal_apoptosis0.60684612
66MP0009333_abnormal_splenocyte_physiolog0.60522101
67MP0002837_dystrophic_cardiac_calcinosis0.60443812
68MP0002405_respiratory_system_inflammati0.57554188
69MP0001963_abnormal_hearing_physiology0.56291973
70MP0000681_abnormal_thyroid_gland0.56083799
71MP0002733_abnormal_thermal_nociception0.55890373
72MP0000026_abnormal_inner_ear0.55699452
73MP0005332_abnormal_amino_acid0.53983341
74MP0002572_abnormal_emotion/affect_behav0.52344331
75MP0002160_abnormal_reproductive_system0.48918089
76MP0003075_altered_response_to0.48856202
77MP0000467_abnormal_esophagus_morphology0.48430636
78MP0009278_abnormal_bone_marrow0.48328320
79MP0000249_abnormal_blood_vessel0.47251841
80MP0002102_abnormal_ear_morphology0.45142840
81MP0002896_abnormal_bone_mineralization0.44993112
82MP0001663_abnormal_digestive_system0.41108545
83MP0000470_abnormal_stomach_morphology0.39904711
84MP0003252_abnormal_bile_duct0.39564908
85MP0001440_abnormal_grooming_behavior0.39460022
86MP0005551_abnormal_eye_electrophysiolog0.38796966
87MP0000377_abnormal_hair_follicle0.38777543
88MP0005389_reproductive_system_phenotype0.38591309
89MP0010386_abnormal_urinary_bladder0.38405068
90MP0009764_decreased_sensitivity_to0.37543520
91MP0003011_delayed_dark_adaptation0.37342228
92MP0000465_gastrointestinal_hemorrhage0.36974272
93MP0005390_skeleton_phenotype0.36863638
94MP0005253_abnormal_eye_physiology0.35703950
95MP0001800_abnormal_humoral_immune0.35552310
96MP0001533_abnormal_skeleton_physiology0.35375667
97MP0001853_heart_inflammation0.35159729
98MP0002419_abnormal_innate_immunity0.34412619
99MP0004134_abnormal_chest_morphology0.34273069
100MP0005645_abnormal_hypothalamus_physiol0.34035249

Predicted human phenotypes

RankGene SetZ-score
1Dynein arm defect of respiratory motile cilia (HP:0012255)8.31536130
2Absent/shortened dynein arms (HP:0200106)8.31536130
3Failure to thrive in infancy (HP:0001531)6.60191714
4Abnormality of cochlea (HP:0000375)6.59776022
5Dysautonomia (HP:0002459)6.31176813
6Poor head control (HP:0002421)6.07841565
7Keratoconjunctivitis sicca (HP:0001097)5.23875269
8Decreased central vision (HP:0007663)5.22207906
9Morphological abnormality of the inner ear (HP:0011390)5.21734119
10Follicular hyperkeratosis (HP:0007502)4.86635105
11Keratoconjunctivitis (HP:0001096)4.83230607
12Tinnitus (HP:0000360)4.60238506
13Bony spicule pigmentary retinopathy (HP:0007737)4.50213960
14Abolished electroretinogram (ERG) (HP:0000550)4.49904294
15Constricted visual fields (HP:0001133)4.47176561
16Lymphangioma (HP:0100764)4.45299635
17Abnormal respiratory motile cilium morphology (HP:0005938)4.42347412
18Abnormal respiratory epithelium morphology (HP:0012253)4.42347412
19Absent phalangeal crease (HP:0006109)4.31280478
20Abnormality of aspartate family amino acid metabolism (HP:0010899)4.18165631
21Abnormal ciliary motility (HP:0012262)4.03794034
22Abnormality of the costochondral junction (HP:0000919)3.87913234
23Cone-rod dystrophy (HP:0000548)3.81594411
24Generalized aminoaciduria (HP:0002909)3.72013917
25Nonimmune hydrops fetalis (HP:0001790)3.67902311
26Abnormal autonomic nervous system physiology (HP:0012332)3.61649202
27Attenuation of retinal blood vessels (HP:0007843)3.53467885
28Abnormal finger flexion creases (HP:0006143)3.53136820
29Ulnar deviation of the wrist (HP:0003049)3.52644608
30Abnormality of pain sensation (HP:0010832)3.50568576
31Impaired pain sensation (HP:0007328)3.50568576
32Morphological abnormality of the middle ear (HP:0008609)3.46542287
33Abnormality of the proximal phalanges of the hand (HP:0009834)3.35476479
34Round ear (HP:0100830)3.35291662
35Recurrent sinusitis (HP:0011108)3.26137823
36Distal arthrogryposis (HP:0005684)3.10803496
37Abnormal respiratory motile cilium physiology (HP:0012261)3.05945244
38Calcaneovalgus deformity (HP:0001848)3.03236829
39Absent eyebrow (HP:0002223)3.00646122
40Decreased electroretinogram (ERG) amplitude (HP:0000654)2.97231568
41Keratoconus (HP:0000563)2.86859449
42Increased corneal curvature (HP:0100692)2.86859449
43Absent eyelashes (HP:0000561)2.77353581
44Elevated circulating parathyroid hormone (PTH) level (HP:0003165)2.74122511
45Deformed tarsal bones (HP:0008119)2.70264868
46Mesangial abnormality (HP:0001966)2.66263152
47Progressive microcephaly (HP:0000253)2.60705963
48Chest pain (HP:0100749)2.50740819
49Pustule (HP:0200039)2.49682795
50Delayed epiphyseal ossification (HP:0002663)2.46174014
51Keratitis (HP:0000491)2.43879557
52Thin bony cortex (HP:0002753)2.39428555
53Abnormality of the nasal septum (HP:0000419)2.38843156
54Tibial bowing (HP:0002982)2.36955697
55Hypotrichosis (HP:0001006)2.35313686
56Stenosis of the external auditory canal (HP:0000402)2.32405171
57Abnormality of the middle phalanx of the 5th finger (HP:0004219)2.30099510
58Abnormality of the middle phalanges of the toes (HP:0010183)2.25428574
59B lymphocytopenia (HP:0010976)2.22219665
60Abnormality of the peritoneum (HP:0002585)2.19932524
61Enlarged epiphyses (HP:0010580)2.16770121
62Abnormality of the phalanges of the 5th finger (HP:0004213)2.14100046
63Poor suck (HP:0002033)2.12063324
64Thyroiditis (HP:0100646)2.11428250
65Short tibia (HP:0005736)2.04805288
66Short 1st metacarpal (HP:0010034)2.04379798
67Aplasia/Hypoplasia of the 1st metacarpal (HP:0010026)2.04379798
68Abnormality of glutamine family amino acid metabolism (HP:0010902)1.99820761
69Epiphyseal dysplasia (HP:0002656)1.97893914
70Abnormality of the renal collecting system (HP:0004742)1.96419281
71Epidermoid cyst (HP:0200040)1.96340573
72Arterial thrombosis (HP:0004420)1.93654451
73Autoimmune thrombocytopenia (HP:0001973)1.92190676
74Amaurosis fugax (HP:0100576)1.91637136
75Aplasia/Hypoplasia of the tibia (HP:0005772)1.90502937
76Cupped ribs (HP:0000887)1.89938215
77Severe Myopia (HP:0011003)1.86338864
78Symptomatic seizures (HP:0011145)1.85503254
79Abnormality of the 1st metacarpal (HP:0010009)1.83806366
80Long nose (HP:0003189)1.83357662
81Vertigo (HP:0002321)1.82648241
82Abnormality of B cell number (HP:0010975)1.81310155
83Severe combined immunodeficiency (HP:0004430)1.79554182
84Photophobia (HP:0000613)1.79405224
85Aplasia/Hypoplasia of the phalanges of the toes (HP:0010173)1.78728626
86Short hallux (HP:0010109)1.76477570
87Lip pit (HP:0100267)1.76477336
88Absent hair (HP:0002298)1.73211393
89Autoimmune hemolytic anemia (HP:0001890)1.73125114
90Symphalangism affecting the phalanges of the hand (HP:0009773)1.72572839
91Neoplasm of the adrenal cortex (HP:0100641)1.72419035
92Flat capital femoral epiphysis (HP:0003370)1.72203116
93Colon cancer (HP:0003003)1.70031369
94Opisthotonus (HP:0002179)1.68455383
95Humeroradial synostosis (HP:0003041)1.66910908
96Synostosis involving the elbow (HP:0003938)1.66910908
97Abnormality of the vertebral endplates (HP:0005106)1.64819398
98Porencephaly (HP:0002132)1.64155907
99Hamartoma of the eye (HP:0010568)1.63901302
100Synostosis of carpal bones (HP:0005048)1.63229170

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAP2K25.85899151
2NUAK14.07375837
3CDK43.48747326
4GRK13.28257702
5STK383.19220022
6ZAK3.13336245
7FRK2.99504103
8TAOK32.67191145
9MAP2K12.43502142
10BMPR1B2.37628338
11CDK122.16923397
12CSNK1G32.13823226
13PIK3CA2.11289806
14VRK22.11072592
15CSNK1A1L1.93490199
16CHEK21.86114857
17TAF11.85642421
18TXK1.74996716
19CSNK1G11.63283526
20CSNK1G21.59901638
21CAMKK21.58360953
22KDR1.55698965
23PLK21.55525523
24PTK21.47077424
25DAPK11.46155394
26CAMK1D1.27102234
27GRK51.25085828
28SMG11.25048240
29ADRBK21.15331179
30MAPK41.10097093
31MAPK151.02484537
32PAK41.00428856
33PRKCZ0.97329400
34ERBB20.96666745
35ZAP700.94550213
36CDK60.93511800
37INSRR0.93269394
38MYLK0.91619163
39PTK2B0.90553579
40SYK0.87746403
41MAP4K10.87729039
42CAMK2B0.83380735
43HIPK20.78654666
44OBSCN0.77931846
45BLK0.77904212
46ABL20.77511038
47VRK10.71953874
48IRAK40.71375472
49KIT0.71131650
50MAP4K20.70449670
51PRKCQ0.69857205
52ERN10.67455985
53MAPKAPK50.67420089
54MAPKAPK20.66283455
55CAMK10.64694786
56MAP2K60.62187110
57MUSK0.61578076
58LCK0.58910629
59GRK60.58427540
60EPHB20.55724896
61CSNK1A10.54997248
62IKBKB0.54830542
63AURKA0.52556313
64MATK0.50693573
65PRKCE0.50546878
66CAMK2A0.50306138
67TESK20.50001066
68PRKCA0.49006096
69ADRBK10.47545515
70MAPK10.45709973
71CAMK1G0.45255974
72CSK0.42635625
73TIE10.42498088
74WNK30.41643536
75PRKD20.41409092
76PRKCH0.40491287
77PRKCI0.40374696
78TEC0.39455256
79PLK30.38451029
80MAPK30.36595391
81MTOR0.35958954
82PRKACA0.35889646
83PRKCB0.34662282
84BTK0.34283476
85TGFBR10.34180721
86PRKACG0.33959911
87LYN0.33956639
88CDK150.32243888
89MAP3K110.32140530
90DAPK30.30606821
91GRK70.30462697
92CDK11A0.30075436
93PRKCG0.30039127
94GSK3A0.29444958
95PRKD10.29074652
96INSR0.29038509
97CDK180.28986474
98PRKCD0.28184714
99MAPK80.27770704
100FYN0.27278807

Predicted pathways (KEGG)

RankGene SetZ-score
1Ascorbate and aldarate metabolism_Homo sapiens_hsa000534.90304490
2Sulfur metabolism_Homo sapiens_hsa009204.35556606
3Pentose and glucuronate interconversions_Homo sapiens_hsa000403.90998224
4Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008603.23660718
5Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005633.09505821
6Olfactory transduction_Homo sapiens_hsa047402.98368043
7Starch and sucrose metabolism_Homo sapiens_hsa005002.97226063
8Steroid hormone biosynthesis_Homo sapiens_hsa001402.94026058
9Drug metabolism - cytochrome P450_Homo sapiens_hsa009822.83139584
10Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009802.80450919
11Retinol metabolism_Homo sapiens_hsa008302.76869709
12Drug metabolism - other enzymes_Homo sapiens_hsa009832.76709964
13Sulfur relay system_Homo sapiens_hsa041222.55887083
14Chemical carcinogenesis_Homo sapiens_hsa052042.55840750
15Intestinal immune network for IgA production_Homo sapiens_hsa046722.42429726
16Histidine metabolism_Homo sapiens_hsa003402.31643291
17Phototransduction_Homo sapiens_hsa047442.05450971
18Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.81011430
19Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.71446475
20SNARE interactions in vesicular transport_Homo sapiens_hsa041301.62753452
21Ether lipid metabolism_Homo sapiens_hsa005651.58793573
22Arachidonic acid metabolism_Homo sapiens_hsa005901.57609279
23Homologous recombination_Homo sapiens_hsa034401.54481266
24Primary immunodeficiency_Homo sapiens_hsa053401.51058002
25Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.48094885
26beta-Alanine metabolism_Homo sapiens_hsa004101.29642415
27Protein digestion and absorption_Homo sapiens_hsa049741.19447154
28Arginine and proline metabolism_Homo sapiens_hsa003301.08993977
29Asthma_Homo sapiens_hsa053101.06365190
30Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.95826341
31Steroid biosynthesis_Homo sapiens_hsa001000.94769387
32Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.94649931
33Tryptophan metabolism_Homo sapiens_hsa003800.94281884
34Lysine degradation_Homo sapiens_hsa003100.91618059
35Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.87010473
36Renin secretion_Homo sapiens_hsa049240.81962273
37Nicotine addiction_Homo sapiens_hsa050330.79523605
38Autoimmune thyroid disease_Homo sapiens_hsa053200.79144623
39ABC transporters_Homo sapiens_hsa020100.79090429
40Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.79009816
41Graft-versus-host disease_Homo sapiens_hsa053320.76366041
42Allograft rejection_Homo sapiens_hsa053300.73763614
43Staphylococcus aureus infection_Homo sapiens_hsa051500.72671494
44Calcium signaling pathway_Homo sapiens_hsa040200.72445310
45Legionellosis_Homo sapiens_hsa051340.70803791
46Hematopoietic cell lineage_Homo sapiens_hsa046400.68468457
47NOD-like receptor signaling pathway_Homo sapiens_hsa046210.67829404
48DNA replication_Homo sapiens_hsa030300.67632186
49Glycerophospholipid metabolism_Homo sapiens_hsa005640.65968866
50Insulin secretion_Homo sapiens_hsa049110.64163849
51Circadian entrainment_Homo sapiens_hsa047130.63696465
52Mismatch repair_Homo sapiens_hsa034300.62562482
53Glycerolipid metabolism_Homo sapiens_hsa005610.61808289
54Taste transduction_Homo sapiens_hsa047420.58990578
55Renin-angiotensin system_Homo sapiens_hsa046140.54582431
56Lysosome_Homo sapiens_hsa041420.52094667
57cAMP signaling pathway_Homo sapiens_hsa040240.51746508
58Alzheimers disease_Homo sapiens_hsa050100.49492705
59Glutathione metabolism_Homo sapiens_hsa004800.47226711
60Parkinsons disease_Homo sapiens_hsa050120.46664246
61ECM-receptor interaction_Homo sapiens_hsa045120.46624214
62Type I diabetes mellitus_Homo sapiens_hsa049400.46622583
63Gastric acid secretion_Homo sapiens_hsa049710.46004273
64Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.44247520
65NF-kappa B signaling pathway_Homo sapiens_hsa040640.42440460
66Dopaminergic synapse_Homo sapiens_hsa047280.42165113
67Rheumatoid arthritis_Homo sapiens_hsa053230.40435296
68Sphingolipid metabolism_Homo sapiens_hsa006000.38595789
69Metabolic pathways_Homo sapiens_hsa011000.36610339
70Nitrogen metabolism_Homo sapiens_hsa009100.36329277
71Maturity onset diabetes of the young_Homo sapiens_hsa049500.29813967
72Peroxisome_Homo sapiens_hsa041460.29663182
73Collecting duct acid secretion_Homo sapiens_hsa049660.29438464
74Oxidative phosphorylation_Homo sapiens_hsa001900.29061464
75Glycosaminoglycan degradation_Homo sapiens_hsa005310.27584681
76Complement and coagulation cascades_Homo sapiens_hsa046100.25293930
77Systemic lupus erythematosus_Homo sapiens_hsa053220.23220358
78Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.22866595
79Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.22414582
80Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.20019220
81Pertussis_Homo sapiens_hsa051330.18718185
82Base excision repair_Homo sapiens_hsa034100.16680750
83Aldosterone synthesis and secretion_Homo sapiens_hsa049250.16276780
84Cardiac muscle contraction_Homo sapiens_hsa042600.16028980
85Type II diabetes mellitus_Homo sapiens_hsa049300.15793010
86Cocaine addiction_Homo sapiens_hsa050300.14596467
87Cysteine and methionine metabolism_Homo sapiens_hsa002700.14593797
88Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.14084594
89Ribosome_Homo sapiens_hsa030100.13978417
90PPAR signaling pathway_Homo sapiens_hsa033200.13531413
91Serotonergic synapse_Homo sapiens_hsa047260.13440312
92Salmonella infection_Homo sapiens_hsa051320.13115825
93Primary bile acid biosynthesis_Homo sapiens_hsa001200.12931560
94Jak-STAT signaling pathway_Homo sapiens_hsa046300.12897077
95Fanconi anemia pathway_Homo sapiens_hsa034600.11611969
96Galactose metabolism_Homo sapiens_hsa000520.11434648
97Antigen processing and presentation_Homo sapiens_hsa046120.11221808
98Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.11213339
99Leishmaniasis_Homo sapiens_hsa051400.10951046
100T cell receptor signaling pathway_Homo sapiens_hsa046600.10411136

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »