UBAC1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1protoporphyrinogen IX biosynthetic process (GO:0006782)9.35083558
2porphyrin-containing compound biosynthetic process (GO:0006779)7.76849002
3heme biosynthetic process (GO:0006783)7.32021548
4oxygen transport (GO:0015671)7.17753060
5gas transport (GO:0015669)7.05940277
6tetrapyrrole biosynthetic process (GO:0033014)6.89267529
7porphyrin-containing compound metabolic process (GO:0006778)5.86084975
8heme metabolic process (GO:0042168)5.44666130
9negative regulation of erythrocyte differentiation (GO:0045647)5.12993184
10muscle filament sliding (GO:0030049)4.97340470
11actin-myosin filament sliding (GO:0033275)4.97340470
12erythrocyte maturation (GO:0043249)4.69278301
13creatine metabolic process (GO:0006600)4.66635393
14tricarboxylic acid cycle (GO:0006099)4.11699377
15sarcomere organization (GO:0045214)4.06483239
16hemoglobin metabolic process (GO:0020027)4.00564545
17DNA replication-dependent nucleosome organization (GO:0034723)3.98841184
18DNA replication-dependent nucleosome assembly (GO:0006335)3.98841184
19mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.98669501
20IMP biosynthetic process (GO:0006188)3.98359973
21proline biosynthetic process (GO:0006561)3.90944947
22IMP metabolic process (GO:0046040)3.88057950
23pigment biosynthetic process (GO:0046148)3.87853318
24erythrocyte development (GO:0048821)3.86255586
25oxidative phosphorylation (GO:0006119)3.83000799
26DNA topological change (GO:0006265)3.82527704
27DNA replication initiation (GO:0006270)3.80955548
28actin-mediated cell contraction (GO:0070252)3.80590793
29tetrapyrrole metabolic process (GO:0033013)3.74153657
30regulation of skeletal muscle contraction (GO:0014819)3.71606850
31nuclear pore complex assembly (GO:0051292)3.65790148
32DNA unwinding involved in DNA replication (GO:0006268)3.65328099
33plasma membrane repair (GO:0001778)3.63965886
34response to insecticide (GO:0017085)3.55003828
35negative regulation of potassium ion transmembrane transporter activity (GO:1901017)3.51096848
36DNA strand elongation involved in DNA replication (GO:0006271)3.48854586
37energy coupled proton transport, down electrochemical gradient (GO:0015985)3.47800365
38ATP synthesis coupled proton transport (GO:0015986)3.47800365
39mitotic sister chromatid segregation (GO:0000070)3.45339020
40oxaloacetate metabolic process (GO:0006107)3.44479341
41regulation of ventricular cardiac muscle cell membrane repolarization (GO:0060307)3.42652636
42myofibril assembly (GO:0030239)3.39859167
43cellular response to thyroid hormone stimulus (GO:0097067)3.36339796
44ribosomal small subunit biogenesis (GO:0042274)3.36205408
45DNA replication checkpoint (GO:0000076)3.34303027
46mitotic chromosome condensation (GO:0007076)3.29466349
47regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.28905130
48regulation of RNA export from nucleus (GO:0046831)3.27865767
49regulation of translational termination (GO:0006449)3.24413607
50DNA strand elongation (GO:0022616)3.23671580
51cardiac myofibril assembly (GO:0055003)3.21416106
52protein localization to kinetochore (GO:0034501)3.19231437
53skeletal muscle contraction (GO:0003009)3.16426781
54granulocyte differentiation (GO:0030851)3.16384822
55regulation of acetyl-CoA biosynthetic process from pyruvate (GO:0010510)3.15634619
56protein localization to chromosome, centromeric region (GO:0071459)3.15194339
57sarcoplasmic reticulum calcium ion transport (GO:0070296)3.14819713
58regulation of acyl-CoA biosynthetic process (GO:0050812)3.14056588
59telomere maintenance via semi-conservative replication (GO:0032201)3.08675864
60iron ion import (GO:0097286)3.08315588
61sister chromatid segregation (GO:0000819)3.07534489
62response to thyroid hormone (GO:0097066)3.07445910
63negative regulation of potassium ion transmembrane transport (GO:1901380)3.05367345
64formation of translation preinitiation complex (GO:0001731)3.04843202
65folic acid-containing compound biosynthetic process (GO:0009396)3.03093399
66regulation of coenzyme metabolic process (GO:0051196)3.02876848
67regulation of cofactor metabolic process (GO:0051193)3.02876848
68pigment metabolic process (GO:0042440)3.00023474
69positive regulation of chromosome segregation (GO:0051984)2.99346904
70definitive hemopoiesis (GO:0060216)2.98445413
71purine nucleotide salvage (GO:0032261)2.98407777
72positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316)2.97187507
73regulation of response to osmotic stress (GO:0047484)2.93173664
74regulation of nucleobase-containing compound transport (GO:0032239)2.92187985
75ribosomal small subunit assembly (GO:0000028)2.91663599
76mitochondrial fusion (GO:0008053)2.91558412
77regulation of histone H3-K4 methylation (GO:0051569)2.90491224
78chromosome condensation (GO:0030261)2.90354115
79succinate metabolic process (GO:0006105)2.89753042
80pentose-phosphate shunt (GO:0006098)2.89277437
81nucleobase-containing small molecule interconversion (GO:0015949)2.89147207
82mitotic nuclear envelope disassembly (GO:0007077)2.88476305
83regulation of mitotic spindle organization (GO:0060236)2.87917249
84NADH metabolic process (GO:0006734)2.87672757
85homocysteine metabolic process (GO:0050667)2.87637622
86response to methylmercury (GO:0051597)2.87522627
87response to lead ion (GO:0010288)2.86079607
88regulation of translational fidelity (GO:0006450)2.84704237
89myeloid cell development (GO:0061515)2.84207398
90aerobic respiration (GO:0009060)2.83196785
91regulation of early endosome to late endosome transport (GO:2000641)2.79636525
92striated muscle contraction (GO:0006941)2.79597784
93carnitine shuttle (GO:0006853)2.78805599
94negative regulation of fatty acid biosynthetic process (GO:0045717)2.76517198
95regulation of attachment of spindle microtubules to kinetochore (GO:0051988)2.76123807
96nuclear envelope disassembly (GO:0051081)2.74943801
97membrane disassembly (GO:0030397)2.74943801
98skeletal muscle tissue regeneration (GO:0043403)2.74094129
99nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)2.74070756
100translational elongation (GO:0006414)2.73341295
101motile cilium assembly (GO:0044458)2.72979245
102viral transcription (GO:0019083)2.70582745
103regulation of histone H3-K27 methylation (GO:0061085)2.70345059
104cardiac muscle cell development (GO:0055013)2.70313629
105erythrocyte differentiation (GO:0030218)2.70092388
106translational termination (GO:0006415)2.69231845
107deoxyribonucleoside monophosphate metabolic process (GO:0009162)2.67638923
108diterpenoid biosynthetic process (GO:0016102)2.67112081
109one-carbon compound transport (GO:0019755)2.66823479
110glycolytic process (GO:0006096)2.65319975
111cardiac muscle contraction (GO:0060048)2.64681194
112chromatin assembly (GO:0031497)2.64528936
113respiratory electron transport chain (GO:0022904)2.64170648
114heart process (GO:0003015)2.64074094
115heart contraction (GO:0060047)2.64074094
116peptidyl-arginine omega-N-methylation (GO:0035247)2.63300463
117mitotic G1 DNA damage checkpoint (GO:0031571)2.62390482
118actin filament-based movement (GO:0030048)2.62187620
119pore complex assembly (GO:0046931)2.60777573
120maturation of SSU-rRNA (GO:0030490)2.60337760
121attachment of spindle microtubules to kinetochore (GO:0008608)2.59934002
122purine nucleoside monophosphate biosynthetic process (GO:0009127)2.58415753
123purine ribonucleoside monophosphate biosynthetic process (GO:0009168)2.58415753
124protein export from nucleus (GO:0006611)2.58294704
125electron transport chain (GO:0022900)2.57562457
126nuclear pore organization (GO:0006999)2.56398892
127platelet formation (GO:0030220)2.56249879
128cellular protein complex disassembly (GO:0043624)2.56114275
129regulation of ryanodine-sensitive calcium-release channel activity (GO:0060314)2.55114286
130DNA packaging (GO:0006323)2.54453887
131telomere maintenance via recombination (GO:0000722)2.53843830
132actomyosin structure organization (GO:0031032)2.53563219
133protein complex disassembly (GO:0043241)2.53535075
134NADPH regeneration (GO:0006740)2.53507845
135skeletal muscle fiber development (GO:0048741)2.53167811
136kinetochore organization (GO:0051383)2.53122990
137potassium ion export (GO:0071435)2.53089188
138viral life cycle (GO:0019058)2.52952214
139negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471)2.52799024
140folic acid metabolic process (GO:0046655)2.52749839
141translational initiation (GO:0006413)2.52598258
142regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (GO:0010880)2.52388297
143regulation of histone H3-K9 methylation (GO:0051570)2.52153424
144anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:02.51597556
145response to arsenic-containing substance (GO:0046685)2.50830243
146nucleoside diphosphate biosynthetic process (GO:0009133)2.50735815
147positive regulation of megakaryocyte differentiation (GO:0045654)2.50563014
148mitotic metaphase plate congression (GO:0007080)2.50262560
149lysine metabolic process (GO:0006553)2.50216467
150protoporphyrinogen IX metabolic process (GO:0046501)10.1199549

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human7.11952062
2EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse5.60091155
3FOXM1_23109430_ChIP-Seq_U2OS_Human4.34764703
4MYC_18555785_ChIP-Seq_MESCs_Mouse3.45424241
5E2F4_17652178_ChIP-ChIP_JURKAT_Human3.08956133
6ZNF263_19887448_ChIP-Seq_K562_Human2.61623226
7FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.52948485
8MYC_19079543_ChIP-ChIP_MESCs_Mouse2.43682273
9MYC_18358816_ChIP-ChIP_MESCs_Mouse2.41257125
10PPARG_19300518_ChIP-PET_3T3-L1_Mouse2.37932683
11MYC_19030024_ChIP-ChIP_MESCs_Mouse2.32095280
12* NCOR1_26117541_ChIP-Seq_K562_Human2.26517805
13CREB1_15753290_ChIP-ChIP_HEK293T_Human2.24889174
14* ETS1_20019798_ChIP-Seq_JURKAT_Human2.21441737
15FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.03122268
16THAP11_20581084_ChIP-Seq_MESCs_Mouse2.02959272
17EGR1_19374776_ChIP-ChIP_THP-1_Human1.99767832
18ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.99284146
19NELFA_20434984_ChIP-Seq_ESCs_Mouse1.98909240
20XRN2_22483619_ChIP-Seq_HELA_Human1.92588176
21* JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.91550739
22* TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.91284220
23SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.90937457
24STAT3_1855785_ChIP-Seq_MESCs_Mouse1.87303514
25TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.84100078
26AR_21909140_ChIP-Seq_LNCAP_Human1.83877889
27EST1_17652178_ChIP-ChIP_JURKAT_Human1.83285343
28KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.82501247
29HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.79926066
30MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.78975075
31MYC_22102868_ChIP-Seq_BL_Human1.76697184
32* GATA1_19941826_ChIP-Seq_K562_Human1.74921789
33GATA1_22025678_ChIP-Seq_K562_Human1.69956573
34* LXR_22292898_ChIP-Seq_THP-1_Human1.69878024
35E2F1_21310950_ChIP-Seq_MCF-7_Human1.62816361
36E2F1_18555785_ChIP-Seq_MESCs_Mouse1.61979614
37CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.61960231
38* GATA2_19941826_ChIP-Seq_K562_Human1.58063002
39MYCN_18555785_ChIP-Seq_MESCs_Mouse1.57402198
40DCP1A_22483619_ChIP-Seq_HELA_Human1.53585961
41ZFX_18555785_ChIP-Seq_MESCs_Mouse1.52645025
42MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.51813093
43* KLF1_20508144_ChIP-Seq_FETAL-LIVER-ERYTHROID_Mouse1.51613495
44GABP_17652178_ChIP-ChIP_JURKAT_Human1.50230074
45KLF4_18555785_ChIP-Seq_MESCs_Mouse1.48999126
46GATA1_19941827_ChIP-Seq_MEL_Mouse1.48920590
47BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.48624030
48DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.47102591
49VDR_23849224_ChIP-Seq_CD4+_Human1.47098850
50CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.46634373
51SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.43156477
52KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.42689394
53NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.40362869
54NANOG_18555785_ChIP-Seq_MESCs_Mouse1.39674655
55ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.38421944
56GATA1_22383799_ChIP-Seq_G1ME_Mouse1.38308384
57* GABP_19822575_ChIP-Seq_HepG2_Human1.37826253
58TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.37678810
59TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.37030408
60TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.36483864
61POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.35685037
62NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.35285866
63CIITA_25753668_ChIP-Seq_RAJI_Human1.34345931
64YY1_21170310_ChIP-Seq_MESCs_Mouse1.34234301
65KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.34032845
66RACK7_27058665_Chip-Seq_MCF-7_Human1.30825626
67SCL_19346495_ChIP-Seq_HPC-7_Human1.26424722
68THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.25004580
69CTCF_27219007_Chip-Seq_ERYTHROID_Human1.24854954
70VDR_21846776_ChIP-Seq_THP-1_Human1.24336903
71FOXP3_21729870_ChIP-Seq_TREG_Human1.24013118
72TTF2_22483619_ChIP-Seq_HELA_Human1.23549956
73E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.23393574
74KDM5A_27292631_Chip-Seq_BREAST_Human1.23063435
75PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.19700722
76ELF1_17652178_ChIP-ChIP_JURKAT_Human1.19013297
77SRY_22984422_ChIP-ChIP_TESTIS_Rat1.16941996
78POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.16203168
79* TCF7_22412390_ChIP-Seq_EML_Mouse1.15945375
80SA1_27219007_Chip-Seq_ERYTHROID_Human1.15350671
81ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.14159661
82YY1_22570637_ChIP-Seq_MALME-3M_Human1.13778014
83NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.13341280
84MAF_26560356_Chip-Seq_TH1_Human1.13094877
85SPI1_23127762_ChIP-Seq_K562_Human1.12290466
86* CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.11432633
87YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.11393869
88ELF1_20517297_ChIP-Seq_JURKAT_Human1.11360181
89CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human1.04766085
90* PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.04699270
91SRF_21415370_ChIP-Seq_HL-1_Mouse1.04477100
92ATF3_27146783_Chip-Seq_COLON_Human1.04476324
93SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.04280541
94HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.04008930
95BCOR_27268052_Chip-Seq_Bcells_Human1.03619442
96ERG_20887958_ChIP-Seq_HPC-7_Mouse1.02529451
97E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.02482332
98NANOG_21062744_ChIP-ChIP_HESCs_Human1.02431383
99HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse1.02024148
100ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.01827834
101TET1_21451524_ChIP-Seq_MESCs_Mouse1.01675610
102ESR1_15608294_ChIP-ChIP_MCF-7_Human1.01528785
103MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.01505448
104CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.00063156
105* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.99704214
106RBPJ_22232070_ChIP-Seq_NCS_Mouse0.99565884
107SOX2_18555785_ChIP-Seq_MESCs_Mouse0.99505300
108POU5F1_18358816_ChIP-ChIP_MESCs_Mouse0.98340673
109CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.98078679
110TFEB_21752829_ChIP-Seq_HELA_Human0.97341524
111FLI1_20887958_ChIP-Seq_HPC-7_Mouse0.97106318
112* KDM2B_26808549_Chip-Seq_K562_Human0.96650955
113* P68_20966046_ChIP-Seq_HELA_Human0.96349386
114MAF_26560356_Chip-Seq_TH2_Human0.95686617
115* FOXP1_21924763_ChIP-Seq_HESCs_Human0.95661152
116EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human0.95050887
117GATA4_21415370_ChIP-Seq_HL-1_Mouse0.94932848
118KDM2B_26808549_Chip-Seq_DND41_Human0.92616628
119* CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.92129424
120KDM5B_21448134_ChIP-Seq_MESCs_Mouse0.90771221
121CTCF_21964334_Chip-Seq_Bcells_Human0.89071360
122OCT4_18692474_ChIP-Seq_MEFs_Mouse0.89015790
123SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse0.88265951
124SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.88211838
125TBX5_21415370_ChIP-Seq_HL-1_Mouse0.88130789
126KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.87877463
127PDX1_19855005_ChIP-ChIP_MIN6_Mouse0.87484438
128ELK3_25401928_ChIP-Seq_HUVEC_Human0.87226543
129ZNF652_21678463_ChIP-ChIP_ZR75-1_Human0.84233490

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003656_abnormal_erythrocyte_physiolo6.03450818
2MP0004147_increased_porphyrin_level5.51960232
3MP0003646_muscle_fatigue4.51462652
4MP0000749_muscle_degeneration4.00293030
5MP0005451_abnormal_body_composition4.00008372
6MP0000751_myopathy3.46013723
7MP0002837_dystrophic_cardiac_calcinosis3.31380176
8MP0004145_abnormal_muscle_electrophysio3.18035044
9MP0003111_abnormal_nucleus_morphology3.01377352
10MP0004084_abnormal_cardiac_muscle2.93377767
11MP0004036_abnormal_muscle_relaxation2.76197603
12MP0000747_muscle_weakness2.74431491
13MP0002269_muscular_atrophy2.57524903
14MP0006036_abnormal_mitochondrial_physio2.57040133
15MP0004215_abnormal_myocardial_fiber2.53504517
16MP0009278_abnormal_bone_marrow2.51952152
17MP0010094_abnormal_chromosome_stability2.46726184
18MP0003693_abnormal_embryo_hatching2.45266655
19MP0004087_abnormal_muscle_fiber2.41385295
20MP0002106_abnormal_muscle_physiology2.30914724
21MP0004957_abnormal_blastocyst_morpholog2.30796845
22MP0005330_cardiomyopathy2.28530833
23MP0000759_abnormal_skeletal_muscle2.25170079
24MP0003077_abnormal_cell_cycle2.14208791
25MP0000750_abnormal_muscle_regeneration2.11297600
26MP0004233_abnormal_muscle_weight2.11085498
27MP0000678_abnormal_parathyroid_gland2.05260139
28MP0008775_abnormal_heart_ventricle1.99871670
29MP0003221_abnormal_cardiomyocyte_apopto1.95455452
30MP0008995_early_reproductive_senescence1.93205475
31MP0004130_abnormal_muscle_cell1.92215084
32MP0005620_abnormal_muscle_contractility1.88434017
33MP0003806_abnormal_nucleotide_metabolis1.87393085
34MP0005369_muscle_phenotype1.79413043
35MP0002132_abnormal_respiratory_system1.78275319
36MP0001730_embryonic_growth_arrest1.72982989
37MP0006035_abnormal_mitochondrial_morpho1.67795225
38MP0003705_abnormal_hypodermis_morpholog1.61175474
39MP0002972_abnormal_cardiac_muscle1.57354274
40MP0005058_abnormal_lysosome_morphology1.49157085
41MP0010352_gastrointestinal_tract_polyps1.48615465
42MP0001544_abnormal_cardiovascular_syste1.48397929
43MP0005385_cardiovascular_system_phenoty1.48397929
44MP0010630_abnormal_cardiac_muscle1.46215720
45MP0005083_abnormal_biliary_tract1.46045208
46MP0003567_abnormal_fetal_cardiomyocyte1.41565718
47MP0002332_abnormal_exercise_endurance1.41530296
48MP0004185_abnormal_adipocyte_glucose1.40924350
49MP0002877_abnormal_melanocyte_morpholog1.39938255
50MP0003137_abnormal_impulse_conducting1.33186234
51MP0008057_abnormal_DNA_replication1.32407177
52MP0000350_abnormal_cell_proliferation1.25142000
53MP0008932_abnormal_embryonic_tissue1.23853905
54MP0003786_premature_aging1.23263144
55MP0005666_abnormal_adipose_tissue1.18641410
56MP0009379_abnormal_foot_pigmentation1.18286030
57MP0008260_abnormal_autophagy1.16854550
58MP0008877_abnormal_DNA_methylation1.15597105
59MP0010307_abnormal_tumor_latency1.15453480
60MP0001697_abnormal_embryo_size1.13810557
61MP0000733_abnormal_muscle_development1.13386969
62MP0002080_prenatal_lethality1.13163152
63MP0001661_extended_life_span1.10513522
64MP0005266_abnormal_metabolism1.10284995
65MP0000358_abnormal_cell_content/1.08991953
66MP0003123_paternal_imprinting1.06934971
67MP0001672_abnormal_embryogenesis/_devel1.05562674
68MP0005380_embryogenesis_phenotype1.05562674
69MP0006138_congestive_heart_failure1.04763943
70MP0008770_decreased_survivor_rate1.04166230
71MP0005464_abnormal_platelet_physiology1.03405736
72MP0004484_altered_response_of1.02855417
73MP0003984_embryonic_growth_retardation1.02631680
74MP0002088_abnormal_embryonic_growth/wei1.00322554
75MP0008058_abnormal_DNA_repair0.99641841
76MP0003191_abnormal_cellular_cholesterol0.98707916
77MP0004085_abnormal_heartbeat0.97486953
78MP0004197_abnormal_fetal_growth/weight/0.95065243
79MP0003172_abnormal_lysosome_physiology0.93788703
80MP0004808_abnormal_hematopoietic_stem0.92895322
81MP0000266_abnormal_heart_morphology0.92201221
82MP0001545_abnormal_hematopoietic_system0.91139213
83MP0005397_hematopoietic_system_phenotyp0.91139213
84MP0002086_abnormal_extraembryonic_tissu0.89272686
85MP0009697_abnormal_copulation0.88681906
86MP0001727_abnormal_embryo_implantation0.87969011
87MP0003718_maternal_effect0.87934008
88MP0000015_abnormal_ear_pigmentation0.81979463
89MP0000313_abnormal_cell_death0.81391675
90MP0009931_abnormal_skin_appearance0.79500133
91MP0002084_abnormal_developmental_patter0.78207408
92MP0002085_abnormal_embryonic_tissue0.76850357
93MP0009672_abnormal_birth_weight0.75898269
94MP0002127_abnormal_cardiovascular_syste0.74909476
95MP0005187_abnormal_penis_morphology0.72223702
96MP0002396_abnormal_hematopoietic_system0.70603514
97MP0005636_abnormal_mineral_homeostasis0.69684644
98MP0003950_abnormal_plasma_membrane0.69616535
99MP0000343_altered_response_to0.67612238
100MP0005375_adipose_tissue_phenotype0.67004344
101MP0009333_abnormal_splenocyte_physiolog0.65924563
102MP0003878_abnormal_ear_physiology0.65236205
103MP0005377_hearing/vestibular/ear_phenot0.65236205
104MP0003879_abnormal_hair_cell0.64786723
105MP0003453_abnormal_keratinocyte_physiol0.62517162
106MP0000609_abnormal_liver_physiology0.61731021
107MP0002019_abnormal_tumor_incidence0.61409135
108MP0005501_abnormal_skin_physiology0.61132659
109MP0003303_peritoneal_inflammation0.59201924
110MP0001529_abnormal_vocalization0.58742041
111MP0001929_abnormal_gametogenesis0.57793911
112MP0002653_abnormal_ependyma_morphology0.56062237
113MP0000490_abnormal_crypts_of0.55361115
114MP0002108_abnormal_muscle_morphology0.54114248
115MP0002971_abnormal_brown_adipose0.53336873
116MP0003566_abnormal_cell_adhesion0.52649698
117MP0003186_abnormal_redox_activity0.51538556
118MP0001849_ear_inflammation0.51211648
119MP0005076_abnormal_cell_differentiation0.51098147
120MP0005384_cellular_phenotype0.50691006
121MP0003828_pulmonary_edema0.50066292
122MP0002210_abnormal_sex_determination0.49343156
123MP0009840_abnormal_foam_cell0.48881600
124MP0008007_abnormal_cellular_replicative0.48125308
125MP0001145_abnormal_male_reproductive0.47133217
126MP0003329_amyloid_beta_deposits0.46446459
127MP0003698_abnormal_male_reproductive0.44497833
128MP0003315_abnormal_perineum_morphology0.43117874

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of the heme biosynthetic pathway (HP:0010472)6.90356065
2Poikilocytosis (HP:0004447)6.13473515
3Exercise-induced muscle cramps (HP:0003710)5.80214439
4Exercise-induced myalgia (HP:0003738)5.39210465
5Muscle fiber inclusion bodies (HP:0100299)5.09736521
6Reticulocytosis (HP:0001923)4.94949001
7Muscle fiber cytoplasmatic inclusion bodies (HP:0100303)4.90170777
8Paralysis (HP:0003470)4.51783912
9Nemaline bodies (HP:0003798)4.47470064
10Cholelithiasis (HP:0001081)4.39043822
11Abnormal hemoglobin (HP:0011902)4.36970941
12Myoglobinuria (HP:0002913)4.31991819
13Muscle hypertrophy of the lower extremities (HP:0008968)4.28055966
14Calf muscle hypertrophy (HP:0008981)4.12496501
15Truncus arteriosus (HP:0001660)4.05783949
16Hyperthyroidism (HP:0000836)3.95050935
17Centrally nucleated skeletal muscle fibers (HP:0003687)3.94944407
18Diaphragmatic weakness (HP:0009113)3.93636915
19Hypochromic microcytic anemia (HP:0004840)3.91663139
20Muscle fiber splitting (HP:0003555)3.91291949
21Distal arthrogryposis (HP:0005684)3.90016610
22Type 1 muscle fiber predominance (HP:0003803)3.88500960
23Acanthocytosis (HP:0001927)3.87798428
24Rhabdomyolysis (HP:0003201)3.79020068
25Abnormal gallbladder morphology (HP:0012437)3.76289356
26Hyporeflexia of lower limbs (HP:0002600)3.71616526
27Difficulty running (HP:0009046)3.58191454
28Myopathic facies (HP:0002058)3.52706651
29Sudden death (HP:0001699)3.52160631
30Abnormality of reticulocytes (HP:0004312)3.49787079
31Hypertensive crisis (HP:0100735)3.42399890
32Myotonia (HP:0002486)3.28756591
33Muscle stiffness (HP:0003552)3.24819416
34Bowel incontinence (HP:0002607)3.23948862
35Ulnar deviation of the wrist (HP:0003049)3.22417947
36Increased connective tissue (HP:0009025)3.22138795
37Insomnia (HP:0100785)3.19918276
38Abnormal large intestine physiology (HP:0012700)3.17023478
39Difficulty climbing stairs (HP:0003551)3.15450451
40EMG: myopathic abnormalities (HP:0003458)3.10828965
41Round ear (HP:0100830)3.10576647
42Pallor (HP:0000980)2.95730313
43Abnormality of the calf musculature (HP:0001430)2.94507706
44Calcaneovalgus deformity (HP:0001848)2.91627135
45Subaortic stenosis (HP:0001682)2.91351198
46Abnormality of the left ventricular outflow tract (HP:0011103)2.91351198
47Abnormality of cells of the erythroid lineage (HP:0012130)2.86962748
48Abnormal number of erythroid precursors (HP:0012131)2.85476883
49Abnormality of the tricuspid valve (HP:0001702)2.85389114
50Ragged-red muscle fibers (HP:0003200)2.78398794
51Atelectasis (HP:0100750)2.71989478
52Areflexia of lower limbs (HP:0002522)2.69569421
53Cholecystitis (HP:0001082)2.68151287
54Abnormal gallbladder physiology (HP:0012438)2.68151287
55Birth length less than 3rd percentile (HP:0003561)2.66908492
56Deformed tarsal bones (HP:0008119)2.62872649
57Ventricular tachycardia (HP:0004756)2.56172769
58Hypoparathyroidism (HP:0000829)2.55158074
59Hyperbilirubinemia (HP:0002904)2.54083419
60Seborrheic dermatitis (HP:0001051)2.48887243
61Rimmed vacuoles (HP:0003805)2.48762668
62Ventricular fibrillation (HP:0001663)2.46777738
63Abnormality of the gallbladder (HP:0005264)2.39762745
64Shoulder girdle muscle weakness (HP:0003547)2.35284791
65EMG: neuropathic changes (HP:0003445)2.27970850
66Distal lower limb amyotrophy (HP:0008944)2.27117278
67Absent phalangeal crease (HP:0006109)2.26819197
68Abnormality of homocysteine metabolism (HP:0010919)2.25739960
69Homocystinuria (HP:0002156)2.25739960
70Lipoatrophy (HP:0100578)2.24206657
71Abnormality of skeletal muscle fiber size (HP:0012084)2.24054876
72Abnormal mitochondria in muscle tissue (HP:0008316)2.21813298
73Decreased activity of mitochondrial respiratory chain (HP:0008972)2.20264858
74Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.20264858
75Ileus (HP:0002595)2.19290657
76Neoplasm of head and neck (HP:0012288)2.18425137
77Esophageal neoplasm (HP:0100751)2.18425137
78Adenoma sebaceum (HP:0009720)2.16173100
79Angiofibromas (HP:0010615)2.16173100
80Acute necrotizing encephalopathy (HP:0006965)2.15450121
81Pelvic girdle muscle weakness (HP:0003749)2.15269223
82Progressive muscle weakness (HP:0003323)2.14805663
83Increased variability in muscle fiber diameter (HP:0003557)2.12055572
84Neck muscle weakness (HP:0000467)2.11853431
85Multiple enchondromatosis (HP:0005701)2.09881337
86Nasal polyposis (HP:0100582)2.03282225
87Achilles tendon contracture (HP:0001771)2.03014737
88Asymmetric septal hypertrophy (HP:0001670)2.02103070
89Ependymoma (HP:0002888)2.01007381
90Ankyloglossia (HP:0010296)2.00592630
91Abnormality of the calcaneus (HP:0008364)2.00466106
92Hypochromic anemia (HP:0001931)1.99676515
93Abnormality of the hip-girdle musculature (HP:0001445)1.98916232
94Abnormality of the musculature of the pelvis (HP:0001469)1.98916232
95Aplasia/Hypoplasia of the sacrum (HP:0008517)1.97411200
96Foot dorsiflexor weakness (HP:0009027)1.95256888
97Increased serum ferritin (HP:0003281)1.93535061
98Nausea (HP:0002018)1.92996722
99Polycythemia (HP:0001901)1.92095094
100Increased muscle lipid content (HP:0009058)1.89784188
101Hepatic necrosis (HP:0002605)1.89368228
102Aplasia/Hypoplasia of the earlobes (HP:0009906)1.88930499
103Abnormality of glycolysis (HP:0004366)1.88582781
104Increased serum pyruvate (HP:0003542)1.88582781
105Nonimmune hydrops fetalis (HP:0001790)1.88164282
106Hepatocellular necrosis (HP:0001404)1.88158955
107Fatigue (HP:0012378)1.86355652
108Palpitations (HP:0001962)1.86080237
109Limb-girdle muscle weakness (HP:0003325)1.85862634
110Abnormal finger flexion creases (HP:0006143)1.85579835
111Distal lower limb muscle weakness (HP:0009053)1.85168207
112Abnormality of the foot musculature (HP:0001436)1.85071462
113Acute encephalopathy (HP:0006846)1.84130255
114Global brain atrophy (HP:0002283)1.83343616
115Abnormality of the nasal mucosa (HP:0000433)1.82733308
116Male infertility (HP:0003251)1.82189570
117Microcytic anemia (HP:0001935)1.81627182
118Abnormality of the Achilles tendon (HP:0005109)1.81466199
119Cutaneous photosensitivity (HP:0000992)1.80980073
120Breech presentation (HP:0001623)1.79160627
121Dilated cardiomyopathy (HP:0001644)1.78165311
122Abnormality of iron homeostasis (HP:0011031)1.78076241
123Frequent falls (HP:0002359)1.77845405
124Increased CSF lactate (HP:0002490)1.77803319
125Dysmetric saccades (HP:0000641)1.77098222
126Increased intramyocellular lipid droplets (HP:0012240)1.76834134
127Exercise intolerance (HP:0003546)1.74923299
128Bulbar palsy (HP:0001283)1.74211656
129Bundle branch block (HP:0011710)1.73857546
130Limb-girdle muscle atrophy (HP:0003797)1.73102362
131Reticulocytopenia (HP:0001896)1.69590354
132Lactic acidosis (HP:0003128)1.68944233
133Conjunctival hamartoma (HP:0100780)1.67744493
134Increased serum lactate (HP:0002151)1.67601291
135Progressive macrocephaly (HP:0004481)1.67343186
136Generalized muscle weakness (HP:0003324)1.67205058
137Peripheral hypomyelination (HP:0007182)1.65984490

Predicted kinase interactions (KEA)

RankGene SetZ-score
1EIF2AK13.88937278
2NEK13.82968645
3OBSCN3.54257090
4TTN3.35437780
5CDC73.17364886
6PDK42.62434811
7PDK32.62434811
8PHKG12.62189766
9PHKG22.62189766
10PRPF4B2.61933609
11TRIB32.59961564
12RIPK42.59786844
13BUB12.54848126
14PKN22.54559450
15NME22.37853758
16WEE12.26399526
17TLK12.20113765
18CLK12.07400480
19SMG11.99678986
20EEF2K1.97001296
21NME11.92931339
22NEK21.89018762
23PBK1.79700487
24MAPKAPK31.75474859
25BCKDK1.68848937
26CDK121.67642808
27IRAK31.65499556
28SCYL21.60832739
29RAF11.55662231
30ZAK1.54563292
31BRSK11.53849927
32STK41.46138203
33TTK1.44661425
34BMX1.42267010
35MAP3K21.40683525
36MAP2K31.32041273
37MAP3K101.25187139
38TRPM71.24790755
39RPS6KB21.24680249
40AURKA1.24462173
41MAP3K81.22491251
42PDK21.22147337
43ICK1.19809293
44ARAF1.15444726
45MAP3K111.15049764
46DYRK31.14087430
47PLK11.06324554
48LIMK11.04547462
49PINK11.02780868
50MAP3K11.02287396
51PLK40.98135514
52AURKB0.97809280
53TESK20.97147933
54CDK40.96449972
55LMTK20.85077023
56KSR10.83611780
57MAPK110.82816460
58MAPK120.82027442
59ILK0.81755209
60CHEK20.79573060
61VRK10.78311332
62PRKD30.77617750
63STK100.76306343
64MAP3K130.75479424
65CHEK10.74851621
66BRSK20.74567408
67AKT20.71605682
68BMPR20.71265619
69MAP3K70.70511635
70KSR20.67060341
71TAOK10.66917379
72SIK10.65843913
73PRKAA10.65208631
74MAP3K90.62874887
75GRK60.61555796
76LRRK20.61065031
77CDK70.60751886
78STK160.60021180
79PDPK10.60008850
80DMPK0.59834793
81PIK3CG0.59477867
82LATS20.56477006
83MUSK0.53005931
84PTK60.52009751
85CCNB10.51602346
86MAP2K20.51380590
87FLT30.51275749
88CDK190.51164227
89TESK10.49998318
90MARK20.49947186
91CDK20.48633538
92MAP2K10.47681063
93ATR0.47630647
94PLK30.47528684
95JAK20.47508709
96ERN10.47287528
97RPS6KC10.46879695
98RPS6KL10.46879695
99DAPK30.46285464
100RIPK10.45907452
101NTRK30.45872930
102CDK140.45351135
103PAK10.44753681
104GRK50.44456291
105MTOR0.44397715
106ALK0.43857159
107PIM10.43307963
108STK240.43075495
109CDK150.42720522
110TSSK60.42069119
111CDK11A0.41987204
112MELK0.40449185
113MAP2K60.40196960
114TAOK20.38707800
115CDC42BPA0.38035193
116CAMK2G0.37992863
117ATM0.37761587
118MAPK100.36959613
119CDK60.36338946
120CDK180.35983132
121CSNK1D0.35959241
122RPS6KA50.35384025
123PRKAA20.35080630
124CDK10.34644726
125MAP3K50.33655793
126SRPK10.33339039
127RET0.32662123
128MST40.32095012
129CSNK2A20.31403332
130RPS6KA40.31393924
131ABL20.31095294
132MAP2K40.30798625
133MARK30.30129285
134KDR0.28729188
135RPS6KA10.28369672
136DYRK1B0.26056387
137DYRK20.24592026
138PDK10.24567996
139BRAF0.23826670

Predicted pathways (KEGG)

RankGene SetZ-score
1Citrate cycle (TCA cycle)_Homo sapiens_hsa000204.21962444
2Butirosin and neomycin biosynthesis_Homo sapiens_hsa005244.03619335
3Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008603.56863400
4DNA replication_Homo sapiens_hsa030303.52420123
52-Oxocarboxylic acid metabolism_Homo sapiens_hsa012103.30310436
6Mismatch repair_Homo sapiens_hsa034302.66910481
7Vitamin B6 metabolism_Homo sapiens_hsa007502.64258067
8Parkinsons disease_Homo sapiens_hsa050122.58434512
9Systemic lupus erythematosus_Homo sapiens_hsa053222.57153154
10Cardiac muscle contraction_Homo sapiens_hsa042602.47715261
11Proteasome_Homo sapiens_hsa030502.40940801
12Carbon metabolism_Homo sapiens_hsa012002.28997641
13Ribosome_Homo sapiens_hsa030102.22473046
14Oxidative phosphorylation_Homo sapiens_hsa001902.11592713
15Cell cycle_Homo sapiens_hsa041102.02540838
16Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.97536925
17RNA transport_Homo sapiens_hsa030131.95290317
18Huntingtons disease_Homo sapiens_hsa050161.85986857
19Biosynthesis of amino acids_Homo sapiens_hsa012301.85145091
20Nucleotide excision repair_Homo sapiens_hsa034201.77971526
21Glycolysis / Gluconeogenesis_Homo sapiens_hsa000101.76044065
22Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.67752217
23Pyruvate metabolism_Homo sapiens_hsa006201.66870536
24Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.62298659
25Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.61317497
26Propanoate metabolism_Homo sapiens_hsa006401.58266043
27Spliceosome_Homo sapiens_hsa030401.58204005
28Alzheimers disease_Homo sapiens_hsa050101.57812550
29Base excision repair_Homo sapiens_hsa034101.57399792
30Acute myeloid leukemia_Homo sapiens_hsa052211.49343035
31One carbon pool by folate_Homo sapiens_hsa006701.47940485
32Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.40945555
33Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054101.40612787
34Other glycan degradation_Homo sapiens_hsa005111.35487181
35Oocyte meiosis_Homo sapiens_hsa041141.33754440
36Homologous recombination_Homo sapiens_hsa034401.32466904
37Alcoholism_Homo sapiens_hsa050341.29826772
38Pentose phosphate pathway_Homo sapiens_hsa000301.21159010
39Dilated cardiomyopathy_Homo sapiens_hsa054141.18947782
40Pyrimidine metabolism_Homo sapiens_hsa002401.15076806
41RNA polymerase_Homo sapiens_hsa030201.13625940
42Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.10865607
43Cysteine and methionine metabolism_Homo sapiens_hsa002701.09443488
44Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.06724843
45mRNA surveillance pathway_Homo sapiens_hsa030151.04478465
46Sulfur relay system_Homo sapiens_hsa041221.03483030
47Fructose and mannose metabolism_Homo sapiens_hsa000510.99721735
48Fatty acid degradation_Homo sapiens_hsa000710.97178371
49Pancreatic cancer_Homo sapiens_hsa052120.92391238
50Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.89523252
51Insulin signaling pathway_Homo sapiens_hsa049100.86945550
52AMPK signaling pathway_Homo sapiens_hsa041520.86863464
53Viral carcinogenesis_Homo sapiens_hsa052030.84884658
54Glucagon signaling pathway_Homo sapiens_hsa049220.84034091
55Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.83804087
56Central carbon metabolism in cancer_Homo sapiens_hsa052300.83216532
57Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.81513678
58p53 signaling pathway_Homo sapiens_hsa041150.80095145
59Fanconi anemia pathway_Homo sapiens_hsa034600.76705930
60Renal cell carcinoma_Homo sapiens_hsa052110.76576850
61Prion diseases_Homo sapiens_hsa050200.75686953
62RNA degradation_Homo sapiens_hsa030180.74057493
63Fatty acid metabolism_Homo sapiens_hsa012120.72481366
64Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.71204566
65Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.69523135
66Fatty acid elongation_Homo sapiens_hsa000620.68701319
67Endometrial cancer_Homo sapiens_hsa052130.68056017
68Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.67154486
69Purine metabolism_Homo sapiens_hsa002300.66400510
70Selenocompound metabolism_Homo sapiens_hsa004500.65647209
71Phenylalanine metabolism_Homo sapiens_hsa003600.63406345
72Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.57502821
73ErbB signaling pathway_Homo sapiens_hsa040120.56338983
74Folate biosynthesis_Homo sapiens_hsa007900.56330815
75Bladder cancer_Homo sapiens_hsa052190.56206072
76Galactose metabolism_Homo sapiens_hsa000520.54690382
77Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.53661601
78Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.53204499
79Viral myocarditis_Homo sapiens_hsa054160.51231612
80Glutathione metabolism_Homo sapiens_hsa004800.50329546
81Adipocytokine signaling pathway_Homo sapiens_hsa049200.49307716
82Insulin resistance_Homo sapiens_hsa049310.48501593
83Tight junction_Homo sapiens_hsa045300.47904095
84HIF-1 signaling pathway_Homo sapiens_hsa040660.47667649
85B cell receptor signaling pathway_Homo sapiens_hsa046620.47420688
86Arginine and proline metabolism_Homo sapiens_hsa003300.46962624
87Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.45881675
88Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.45415036
89Thyroid cancer_Homo sapiens_hsa052160.44447501
90Type II diabetes mellitus_Homo sapiens_hsa049300.42997193
91Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.42836559
92mTOR signaling pathway_Homo sapiens_hsa041500.42381540
93Basal transcription factors_Homo sapiens_hsa030220.42147641
94Carbohydrate digestion and absorption_Homo sapiens_hsa049730.41065567
95Metabolic pathways_Homo sapiens_hsa011000.39195685
96Epstein-Barr virus infection_Homo sapiens_hsa051690.39065581
97Cyanoamino acid metabolism_Homo sapiens_hsa004600.38955242
98Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.38583108
99Fatty acid biosynthesis_Homo sapiens_hsa000610.38277220
100Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.38053124
101Apoptosis_Homo sapiens_hsa042100.36276834
102Tyrosine metabolism_Homo sapiens_hsa003500.35584572
103Non-small cell lung cancer_Homo sapiens_hsa052230.35434316
104Synaptic vesicle cycle_Homo sapiens_hsa047210.34185827
105Longevity regulating pathway - mammal_Homo sapiens_hsa042110.33417295
106Non-homologous end-joining_Homo sapiens_hsa034500.33345697
107Thyroid hormone signaling pathway_Homo sapiens_hsa049190.32741249
108Oxytocin signaling pathway_Homo sapiens_hsa049210.32428408
109Neurotrophin signaling pathway_Homo sapiens_hsa047220.31430556
110Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.30874828
111Glycerophospholipid metabolism_Homo sapiens_hsa005640.30858250
112Long-term potentiation_Homo sapiens_hsa047200.28044670
113AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.26668217
114VEGF signaling pathway_Homo sapiens_hsa043700.25321165
115Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.24229803
116Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.24044623
117HTLV-I infection_Homo sapiens_hsa051660.22958925
118Prolactin signaling pathway_Homo sapiens_hsa049170.22211198
119Arginine biosynthesis_Homo sapiens_hsa002200.20591599
120Starch and sucrose metabolism_Homo sapiens_hsa005000.19619569
121Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.18933072
122PPAR signaling pathway_Homo sapiens_hsa033200.18361797
123Small cell lung cancer_Homo sapiens_hsa052220.18133898
124Chronic myeloid leukemia_Homo sapiens_hsa052200.17592375
125cGMP-PKG signaling pathway_Homo sapiens_hsa040220.15330207
126Gap junction_Homo sapiens_hsa045400.15092659
127Glioma_Homo sapiens_hsa052140.14796956
128FoxO signaling pathway_Homo sapiens_hsa040680.14437453
129Regulation of autophagy_Homo sapiens_hsa041400.13842015
130Lysine degradation_Homo sapiens_hsa003100.13541244

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