UBALD1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1modulation by virus of host process (GO:0019054)5.66042792
2synaptic vesicle maturation (GO:0016188)5.31657855
3negative regulation of erythrocyte differentiation (GO:0045647)5.27717254
4modulation by symbiont of host cellular process (GO:0044068)5.07224173
5regulation of short-term neuronal synaptic plasticity (GO:0048172)4.35395704
6positive regulation of excitatory postsynaptic membrane potential (GO:2000463)4.30158962
7poly(A)+ mRNA export from nucleus (GO:0016973)4.20765965
8dendritic spine morphogenesis (GO:0060997)4.18044147
9neuronal action potential propagation (GO:0019227)4.09902630
10regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act3.88927091
11locomotory exploration behavior (GO:0035641)3.87093418
12synaptic vesicle exocytosis (GO:0016079)3.84481784
13negative regulation of viral release from host cell (GO:1902187)3.83350917
14vocalization behavior (GO:0071625)3.83331780
15negative regulation of cell size (GO:0045792)3.81001042
16positive regulation of calcium ion-dependent exocytosis (GO:0045956)3.80870228
17dendritic spine organization (GO:0097061)3.80356283
18regulation of neuronal synaptic plasticity (GO:0048168)3.79625476
19regulation of mammary gland epithelial cell proliferation (GO:0033599)3.69523641
20regulation of long-term neuronal synaptic plasticity (GO:0048169)3.57614372
21apoptotic process involved in morphogenesis (GO:0060561)3.56031251
22glutamate secretion (GO:0014047)3.52219660
23modulation by virus of host morphology or physiology (GO:0019048)3.49924890
24regulation of chromatin binding (GO:0035561)3.48235765
25regulation of ARF GTPase activity (GO:0032312)3.48024092
26regulation of synapse structural plasticity (GO:0051823)3.47239189
273-UTR-mediated mRNA stabilization (GO:0070935)3.45295749
28regulation of glutamate receptor signaling pathway (GO:1900449)3.43517549
29regulation of synaptic vesicle exocytosis (GO:2000300)3.42410927
30mannose metabolic process (GO:0006013)3.40261191
31activation of MAPKKK activity (GO:0000185)3.37035518
32negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471)3.34767451
33positive regulation of neurotransmitter secretion (GO:0001956)3.32489994
34intracellular estrogen receptor signaling pathway (GO:0030520)3.31249712
35ionotropic glutamate receptor signaling pathway (GO:0035235)3.30340168
36regulation of early endosome to late endosome transport (GO:2000641)3.28696199
37neutrophil activation involved in immune response (GO:0002283)3.27588440
38neuromuscular process controlling posture (GO:0050884)3.22736825
39macrophage activation involved in immune response (GO:0002281)3.22167795
40NIK/NF-kappaB signaling (GO:0038061)3.19927592
41synaptic vesicle docking involved in exocytosis (GO:0016081)3.19192099
42regulation of synaptic vesicle transport (GO:1902803)3.14454000
43G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)3.14176320
44positive regulation of synaptic transmission, GABAergic (GO:0032230)3.13459868
45positive regulation of synaptic transmission, dopaminergic (GO:0032226)3.13324203
46activation of Rac GTPase activity (GO:0032863)3.11939332
47positive regulation of Cdc42 GTPase activity (GO:0043089)3.11044985
48glycine transport (GO:0015816)3.10793071
49positive regulation of histone deacetylation (GO:0031065)3.08351275
50cell-cell junction maintenance (GO:0045217)3.08296176
51protein localization to synapse (GO:0035418)3.05613026
52long-term memory (GO:0007616)3.04035253
53adherens junction assembly (GO:0034333)2.99827055
54stress fiber assembly (GO:0043149)2.98540399
55synaptic transmission, glutamatergic (GO:0035249)2.97455284
56modulation by organism of defense response of other organism involved in symbiotic interaction (GO:02.96526061
57positive regulation by organism of defense response of other organism involved in symbiotic interact2.96526061
58modulation by symbiont of host immune response (GO:0052553)2.96526061
59positive regulation by symbiont of host defense response (GO:0052509)2.96526061
60modulation by symbiont of host defense response (GO:0052031)2.96526061
61modulation by organism of immune response of other organism involved in symbiotic interaction (GO:002.96526061
62ribosomal small subunit biogenesis (GO:0042274)2.96436335
63positive T cell selection (GO:0043368)2.96042237
64cell migration in hindbrain (GO:0021535)2.95522405
65positive regulation of membrane potential (GO:0045838)2.95251071
66response to peptidoglycan (GO:0032494)2.92289496
67regulation of synaptic plasticity (GO:0048167)2.90619971
68positive regulation of neurotransmitter transport (GO:0051590)2.89999392
69regulation of excitatory postsynaptic membrane potential (GO:0060079)2.88281362
70focal adhesion assembly (GO:0048041)2.87893810
71cell-substrate adherens junction assembly (GO:0007045)2.87893810
72regulation of ARF protein signal transduction (GO:0032012)2.87639666
73positive regulation of synapse maturation (GO:0090129)2.86678081
74exploration behavior (GO:0035640)2.86347293
75synaptic vesicle endocytosis (GO:0048488)2.85948763
76neuromuscular process controlling balance (GO:0050885)2.85730779
77cerebellar Purkinje cell layer development (GO:0021680)2.85174576
78regulation of T-helper 2 cell differentiation (GO:0045628)2.84887272
79regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway (GO:19022352.84581775
80protein localization to endosome (GO:0036010)2.84108479
81sodium ion export (GO:0071436)2.83112822
82maternal placenta development (GO:0001893)2.81779812
83transmission of nerve impulse (GO:0019226)2.80901947
84regulation of autophagic vacuole assembly (GO:2000785)2.76246499
85regulation of dendritic spine morphogenesis (GO:0061001)2.74817824
86membrane depolarization during cardiac muscle cell action potential (GO:0086012)2.74715173
87regulation of vesicle fusion (GO:0031338)2.73901029
88regulation of translational fidelity (GO:0006450)2.73471416
89cerebellar Purkinje cell differentiation (GO:0021702)2.72780499
90negative regulation of cell killing (GO:0031342)2.71755044
91negative regulation of leukocyte mediated cytotoxicity (GO:0001911)2.71755044
92positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling2.67816639
93adult walking behavior (GO:0007628)2.67381025
94semaphorin-plexin signaling pathway (GO:0071526)2.66843252
95signal complex assembly (GO:0007172)2.66206514
96adenosine receptor signaling pathway (GO:0001973)2.65861361
97response to isoquinoline alkaloid (GO:0014072)2.65778959
98positive regulation of type I interferon-mediated signaling pathway (GO:0060340)2.64916268
99glutamate receptor signaling pathway (GO:0007215)2.64625959
100positive regulation of protein dephosphorylation (GO:0035307)2.63075933
101activation of JUN kinase activity (GO:0007257)2.62983975
102regulation of synapse maturation (GO:0090128)2.62911744
103negative regulation of viral entry into host cell (GO:0046597)2.62821509
104neuron-neuron synaptic transmission (GO:0007270)2.62778789
105neurotransmitter secretion (GO:0007269)2.62045799
106positive thymic T cell selection (GO:0045059)2.61865635
107L-amino acid import (GO:0043092)2.61555291
108regulation of viral release from host cell (GO:1902186)2.61316438
109atrioventricular valve morphogenesis (GO:0003181)2.61285296
110cellular potassium ion homeostasis (GO:0030007)2.60888895
111thymic T cell selection (GO:0045061)2.60607183
112regulation of postsynaptic membrane potential (GO:0060078)2.60485066
113peptidyl-tyrosine autophosphorylation (GO:0038083)2.60472770
114axon ensheathment in central nervous system (GO:0032291)2.58715309
115central nervous system myelination (GO:0022010)2.58715309
116negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665)2.56034625
117pentose-phosphate shunt (GO:0006098)2.55804150
118protein retention in ER lumen (GO:0006621)2.55479154
119positive regulation of receptor recycling (GO:0001921)2.55402123
120positive regulation of dendritic spine development (GO:0060999)2.54628121
121response to morphine (GO:0043278)2.54050433
122negative regulation of inclusion body assembly (GO:0090084)2.53955465
123protein targeting to plasma membrane (GO:0072661)2.52060078
124negative regulation of phosphatidylinositol 3-kinase signaling (GO:0014067)2.51531545
125retrograde transport, endosome to Golgi (GO:0042147)2.49542324
126vascular endothelial growth factor receptor signaling pathway (GO:0048010)2.49331782
127chemosensory behavior (GO:0007635)2.49231913
128negative regulation of calcium ion transport into cytosol (GO:0010523)2.49056686
129neuron cell-cell adhesion (GO:0007158)2.48964968
130neuronal ion channel clustering (GO:0045161)2.48825289
131germinal center formation (GO:0002467)2.48775948
132amyloid precursor protein catabolic process (GO:0042987)2.46780678
133long term synaptic depression (GO:0060292)2.44890968
134adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191)2.44856230
135regulation of necrotic cell death (GO:0010939)2.44694023
136GDP-mannose metabolic process (GO:0019673)2.44663846
137T cell selection (GO:0045058)2.44630917
138response to muramyl dipeptide (GO:0032495)2.44287398
139proline biosynthetic process (GO:0006561)2.44106858
140presynaptic membrane organization (GO:0097090)2.43856967
141regulation of monocyte differentiation (GO:0045655)2.43786567
142regulation of apoptotic process involved in morphogenesis (GO:1902337)2.43178347
143negative regulation of fatty acid transport (GO:2000192)2.42848893
144dopamine receptor signaling pathway (GO:0007212)2.42386760
145histone H4-K12 acetylation (GO:0043983)2.42217746
146response to laminar fluid shear stress (GO:0034616)2.42213118
147regulation of respiratory gaseous exchange by neurological system process (GO:0002087)2.41963711
148histone H4 deacetylation (GO:0070933)2.41745092
149positive regulation of Rap GTPase activity (GO:0032854)2.41502018
150keratinocyte development (GO:0003334)2.41143671
151membrane depolarization (GO:0051899)2.40784366
152layer formation in cerebral cortex (GO:0021819)2.40366047
153negative regulation of amyloid precursor protein catabolic process (GO:1902992)2.40060992
154modification by symbiont of host morphology or physiology (GO:0044003)2.39331015
155regulation of dendritic spine development (GO:0060998)2.38996690
156cellular response to virus (GO:0098586)2.38272864
157regulation of vacuole organization (GO:0044088)2.37896813
158auditory behavior (GO:0031223)2.37782423
159oxygen transport (GO:0015671)2.37417626
160learning (GO:0007612)2.36762195
161long-term synaptic potentiation (GO:0060291)2.36689734
162establishment of mitochondrion localization, microtubule-mediated (GO:0034643)2.35889684
163mitochondrion transport along microtubule (GO:0047497)2.35889684
164glucose catabolic process (GO:0006007)2.35737259
165embryonic process involved in female pregnancy (GO:0060136)2.35579272
166endoplasmic reticulum calcium ion homeostasis (GO:0032469)2.35114899
167regulation of respiratory system process (GO:0044065)2.34778202
168UV protection (GO:0009650)2.34565491
169regulation of leukocyte degranulation (GO:0043300)2.34425117
170antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G2.34120071
171protein insertion into membrane (GO:0051205)2.33523993
172positive regulation of fibroblast migration (GO:0010763)2.32368555
173regulation of type I interferon-mediated signaling pathway (GO:0060338)2.31878085
174regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)2.31592775
175respiratory system process (GO:0003016)2.31470989
176prepulse inhibition (GO:0060134)2.31321594
177apoptotic process involved in development (GO:1902742)2.30583887
178negative regulation of granulocyte differentiation (GO:0030853)2.29537760
179mechanosensory behavior (GO:0007638)2.29403669
180negative regulation of necroptotic process (GO:0060546)2.29283279
181protein complex localization (GO:0031503)2.28592881
182response to amphetamine (GO:0001975)2.28189151
183planar cell polarity pathway involved in neural tube closure (GO:0090179)2.27985469
184regulation of neurotransmitter secretion (GO:0046928)2.27831860
185positive regulation of protein deacetylation (GO:0090312)2.27010091
186regulation of hydrogen peroxide metabolic process (GO:0010310)2.26595464
187regulation of ruffle assembly (GO:1900027)2.26456159
188skin morphogenesis (GO:0043589)2.25789142
189Arp2/3 complex-mediated actin nucleation (GO:0034314)2.24987155
190positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S tr2.24467044
191regulation of myeloid leukocyte mediated immunity (GO:0002886)2.24401773
192membrane depolarization during action potential (GO:0086010)2.24155820
193cytoskeletal anchoring at plasma membrane (GO:0007016)2.24118348
194response to auditory stimulus (GO:0010996)2.23864741
195neuromuscular process (GO:0050905)2.23263283
196innervation (GO:0060384)2.22649561

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human3.60899295
2TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat3.56474830
3EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse3.32643069
4RARB_27405468_Chip-Seq_BRAIN_Mouse2.82584403
5STAT6_21828071_ChIP-Seq_BEAS2B_Human2.56813881
6KDM2B_26808549_Chip-Seq_SUP-B15_Human2.45575339
7TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse2.42594229
8SUZ12_27294783_Chip-Seq_ESCs_Mouse2.42018583
9ZFP281_18757296_ChIP-ChIP_E14_Mouse2.39230944
10DNAJC2_21179169_ChIP-ChIP_NT2_Human2.38176063
11RARG_19884340_ChIP-ChIP_MEFs_Mouse2.30514025
12EZH2_27294783_Chip-Seq_ESCs_Mouse2.25034919
13JARID2_20064375_ChIP-Seq_MESCs_Mouse2.24361372
14IKZF1_21737484_ChIP-ChIP_HCT116_Human2.17747680
15DROSHA_22980978_ChIP-Seq_HELA_Human2.11952232
16JARID2_20075857_ChIP-Seq_MESCs_Mouse2.11210881
17ZFP281_18358816_ChIP-ChIP_MESCs_Mouse2.07359259
18REST_21632747_ChIP-Seq_MESCs_Mouse2.06675585
19RNF2_18974828_ChIP-Seq_MESCs_Mouse2.06450351
20EZH2_18974828_ChIP-Seq_MESCs_Mouse2.06450351
21NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human2.04809504
22KDM2B_26808549_Chip-Seq_K562_Human2.04761375
23LXR_22292898_ChIP-Seq_THP-1_Human2.03148439
24SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.03065745
25SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.97867209
26KDM2B_26808549_Chip-Seq_DND41_Human1.95013998
27RNF2_27304074_Chip-Seq_ESCs_Mouse1.93934315
28MYC_22102868_ChIP-Seq_BL_Human1.91399662
29ZFP281_27345836_Chip-Seq_ESCs_Mouse1.88253959
30REST_18959480_ChIP-ChIP_MESCs_Mouse1.84714176
31SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.83987568
32VDR_21846776_ChIP-Seq_THP-1_Human1.80745937
33ERG_21242973_ChIP-ChIP_JURKAT_Human1.77852898
34EZH2_27304074_Chip-Seq_ESCs_Mouse1.77526733
35MTF2_20144788_ChIP-Seq_MESCs_Mouse1.77322367
36SRY_22984422_ChIP-ChIP_TESTIS_Rat1.75961873
37CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.72491641
38THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.71312777
39RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.71179479
40PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.69995475
41SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.68369811
42CTCF_27219007_Chip-Seq_Bcells_Human1.67858829
43MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.67181343
44SA1_27219007_Chip-Seq_ERYTHROID_Human1.64834687
45SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.63889863
46P68_20966046_ChIP-Seq_HELA_Human1.61249976
47SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.59905495
48ZNF263_19887448_ChIP-Seq_K562_Human1.59603686
49EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.59204173
50EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.59133298
51KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.56191730
52MAF_26560356_Chip-Seq_TH1_Human1.55925654
53RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.52995585
54TET1_21451524_ChIP-Seq_MESCs_Mouse1.52526429
55NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.51154996
56TCF7_22412390_ChIP-Seq_EML_Mouse1.50101281
57TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.47181030
58VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.45927641
59WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.45066557
60SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.43902058
61UTX_26944678_Chip-Seq_JUKART_Human1.43795499
62KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.43055829
63KDM2B_26808549_Chip-Seq_JURKAT_Human1.42920238
64RACK7_27058665_Chip-Seq_MCF-7_Human1.40864929
65BCL6_27268052_Chip-Seq_Bcells_Human1.39744928
66DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.39706084
67RING1B_27294783_Chip-Seq_ESCs_Mouse1.38637723
68CTCF_27219007_Chip-Seq_ERYTHROID_Human1.37463574
69YY1_22570637_ChIP-Seq_MALME-3M_Human1.34671732
70SMC4_20622854_ChIP-Seq_HELA_Human1.33274359
71RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.32913279
72ELF1_20517297_ChIP-Seq_JURKAT_Human1.32672454
73CREB1_26743006_Chip-Seq_LNCaP_Human1.32435139
74RUNX1_22412390_ChIP-Seq_EML_Mouse1.31813140
75ELK3_25401928_ChIP-Seq_HUVEC_Human1.31682750
76EED_16625203_ChIP-ChIP_MESCs_Mouse1.29307436
77GATA1_26923725_Chip-Seq_HPCs_Mouse1.28690423
78NCOR1_26117541_ChIP-Seq_K562_Human1.28601100
79TP53_20018659_ChIP-ChIP_R1E_Mouse1.28543140
80AR_21572438_ChIP-Seq_LNCaP_Human1.28216525
81OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.25868228
82SA1_27219007_Chip-Seq_Bcells_Human1.23569989
83CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.22452277
84E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.22304025
85KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.22271369
86MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human1.22021128
87RING1B_27294783_Chip-Seq_NPCs_Mouse1.21697195
88GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.20065931
89ESR2_21235772_ChIP-Seq_MCF-7_Human1.19041743
90TET1_21490601_ChIP-Seq_MESCs_Mouse1.18950321
91SREBP2_21459322_ChIP-Seq_LIVER_Mouse1.18918098
92TP53_22127205_ChIP-Seq_IMR90_Human1.18891248
93CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.18588958
94OCT4_19829295_ChIP-Seq_ESCs_Human1.18346342
95KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.16165407
96E2F1_20622854_ChIP-Seq_HELA_Human1.15462409
97PHF8_20622854_ChIP-Seq_HELA_Human1.15387868
98CTCF_26484167_Chip-Seq_Bcells_Mouse1.15029408
99UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.14522522
100CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.14256246
101EGR1_19374776_ChIP-ChIP_THP-1_Human1.14076556
102TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.13896277
103SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.13800899
104SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.13252495
105PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.13150902
106GATA1_22383799_ChIP-Seq_G1ME_Mouse1.13128885
107CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.12898900
108ATF3_27146783_Chip-Seq_COLON_Human1.12563539
109PU.1_20513432_ChIP-Seq_Bcells_Mouse1.12527489
110CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.12491107
111NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.11351164
112RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.11099047
113TP63_17297297_ChIP-ChIP_HaCaT_Human1.10994955
114BRD4_27068464_Chip-Seq_AML-cells_Mouse1.10961088
115SETDB1_19884255_ChIP-Seq_MESCs_Mouse1.10185953
116P300_27058665_Chip-Seq_ZR-75-30cells_Human1.09453743
117GATA1_19941827_ChIP-Seq_MEL_Mouse1.09427640
118PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.08461414
119CTCF_21964334_Chip-Seq_Bcells_Human1.08102063
120ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.07780538
121HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.07492918
122SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.07289369
123KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.06364340
124CTCF_21964334_ChIP-Seq_BJAB-B_Human1.05608552
125NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.04771627
126RUNX1_27514584_Chip-Seq_MCF-7_Human1.03326329
127RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.03182951
128SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.01788444
129CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.01246933
130TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.00355531
131ETS1_21867929_ChIP-Seq_TH2_Mouse0.99984360
132RARB_24833708_ChIP-Seq_LIVER_Mouse0.98173374
133TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.97811643
134SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.97803198
135FOXP1_21924763_ChIP-Seq_HESCs_Human0.97798265
136RARA_24833708_ChIP-Seq_LIVER_Mouse0.97418552
137EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse0.97366396
138BCOR_27268052_Chip-Seq_Bcells_Human0.97254509
139MAF_26560356_Chip-Seq_TH2_Human0.97043421
140CTCF_20526341_ChIP-Seq_ESCs_Human0.96530280
141MEIS1_20887958_ChIP-Seq_HPC-7_Mouse0.96396596
142TP63_22573176_ChIP-Seq_HFKS_Human0.94478478
143TP53_23651856_ChIP-Seq_MEFs_Mouse0.93988779
144DMRT1_23473982_ChIP-Seq_TESTES_Mouse0.93175648
145SMAD1_18555785_ChIP-Seq_MESCs_Mouse0.91210601
146WT1_25993318_ChIP-Seq_PODOCYTE_Human0.90550222
147VDR_24763502_ChIP-Seq_THP-1_Human0.90499705

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity5.57171298
2MP0003705_abnormal_hypodermis_morpholog3.82525906
3MP0003436_decreased_susceptibility_to3.31365324
4MP0003635_abnormal_synaptic_transmissio3.27166583
5MP0004270_analgesia3.26589163
6MP0003880_abnormal_central_pattern3.19491741
7MP0009278_abnormal_bone_marrow3.03528950
8MP0005423_abnormal_somatic_nervous2.99727777
9MP0005451_abnormal_body_composition2.99406671
10MP0005058_abnormal_lysosome_morphology2.80554519
11MP0008260_abnormal_autophagy2.71809318
12MP0009745_abnormal_behavioral_response2.60409262
13MP0002063_abnormal_learning/memory/cond2.59535418
14MP0005076_abnormal_cell_differentiation2.58157299
15MP0002653_abnormal_ependyma_morphology2.52959626
16MP0009840_abnormal_foam_cell2.43347296
17MP0002249_abnormal_larynx_morphology2.36480240
18MP0002064_seizures2.36098535
19MP0001486_abnormal_startle_reflex2.30926114
20MP0002572_abnormal_emotion/affect_behav2.28603071
21MP0008569_lethality_at_weaning2.24880582
22MP0002272_abnormal_nervous_system2.22422549
23MP0002822_catalepsy2.18859683
24MP0003283_abnormal_digestive_organ2.11184182
25MP0009046_muscle_twitch2.08068990
26MP0001501_abnormal_sleep_pattern2.04171596
27MP0008961_abnormal_basal_metabolism2.01991623
28MP0001968_abnormal_touch/_nociception1.99159756
29MP0001529_abnormal_vocalization1.98690013
30MP0001849_ear_inflammation1.92790515
31MP0003879_abnormal_hair_cell1.83779790
32MP0002734_abnormal_mechanical_nocicepti1.79459723
33MP0002557_abnormal_social/conspecific_i1.75511281
34MP0002089_abnormal_postnatal_growth/wei1.70858140
35MP0004185_abnormal_adipocyte_glucose1.70446681
36MP0001545_abnormal_hematopoietic_system1.68392556
37MP0005397_hematopoietic_system_phenotyp1.68392556
38MP0004811_abnormal_neuron_physiology1.66969926
39MP0004947_skin_inflammation1.66187430
40MP0001502_abnormal_circadian_rhythm1.64530671
41MP0001970_abnormal_pain_threshold1.63290343
42MP0009333_abnormal_splenocyte_physiolog1.57024141
43MP0002184_abnormal_innervation1.56513033
44MP0004142_abnormal_muscle_tone1.55976639
45MP0002733_abnormal_thermal_nociception1.55740613
46MP0004858_abnormal_nervous_system1.52940511
47MP0003329_amyloid_beta_deposits1.52938213
48MP0000858_altered_metastatic_potential1.50775048
49MP0005499_abnormal_olfactory_system1.49676903
50MP0005394_taste/olfaction_phenotype1.49676903
51MP0003191_abnormal_cellular_cholesterol1.49540313
52MP0002735_abnormal_chemical_nociception1.47692828
53MP0000681_abnormal_thyroid_gland1.46468439
54MP0002419_abnormal_innate_immunity1.45283007
55MP0002736_abnormal_nociception_after1.45243516
56MP0005375_adipose_tissue_phenotype1.43210223
57MP0005025_abnormal_response_to1.42182793
58MP0000003_abnormal_adipose_tissue1.41584939
59MP0004133_heterotaxia1.41285723
60MP0003566_abnormal_cell_adhesion1.40069889
61MP0000750_abnormal_muscle_regeneration1.38812733
62MP0000955_abnormal_spinal_cord1.32662363
63MP0003279_aneurysm1.30725549
64MP0005666_abnormal_adipose_tissue1.29050124
65MP0001533_abnormal_skeleton_physiology1.28705219
66MP0002751_abnormal_autonomic_nervous1.28432872
67MP0002067_abnormal_sensory_capabilities1.27284904
68MP0002882_abnormal_neuron_morphology1.27077360
69MP0000604_amyloidosis1.25036984
70MP0005000_abnormal_immune_tolerance1.22422815
71MP0002998_abnormal_bone_remodeling1.22061485
72MP0002877_abnormal_melanocyte_morpholog1.20885782
73MP0001485_abnormal_pinna_reflex1.20713763
74MP0002066_abnormal_motor_capabilities/c1.20563929
75MP0004381_abnormal_hair_follicle1.19453793
76MP0005645_abnormal_hypothalamus_physiol1.17179755
77MP0000685_abnormal_immune_system1.16143410
78MP0000778_abnormal_nervous_system1.15144053
79MP0006292_abnormal_olfactory_placode1.14350527
80MP0008789_abnormal_olfactory_epithelium1.13123729
81MP0003119_abnormal_digestive_system1.12037971
82MP0001440_abnormal_grooming_behavior1.11727886
83MP0000920_abnormal_myelination1.08820586
84MP0002420_abnormal_adaptive_immunity1.05910211
85MP0002152_abnormal_brain_morphology1.05832153
86MP0004510_myositis1.05174049
87MP0001819_abnormal_immune_cell1.04863081
88MP0003183_abnormal_peptide_metabolism1.03885974
89MP0005390_skeleton_phenotype1.03498318
90MP0004885_abnormal_endolymph1.03217462
91MP0002398_abnormal_bone_marrow1.03124445
92MP0005083_abnormal_biliary_tract1.02971138
93MP0005623_abnormal_meninges_morphology1.02891797
94MP0008872_abnormal_physiological_respon1.01631368
95MP0004145_abnormal_muscle_electrophysio1.01523413
96MP0001790_abnormal_immune_system1.00505687
97MP0005387_immune_system_phenotype1.00505687
98MP0002909_abnormal_adrenal_gland1.00454458
99MP0004742_abnormal_vestibular_system1.00398414
100MP0003123_paternal_imprinting0.98979266
101MP0002723_abnormal_immune_serum0.98870203
102MP0008007_abnormal_cellular_replicative0.98187010
103MP0001873_stomach_inflammation0.97997320
104MP0002254_reproductive_system_inflammat0.97091648
105MP0009384_cardiac_valve_regurgitation0.96890606
106MP0008995_early_reproductive_senescence0.96562994
107MP0004233_abnormal_muscle_weight0.96281186
108MP0003938_abnormal_ear_development0.95767385
109MP0005501_abnormal_skin_physiology0.95285490
110MP0003763_abnormal_thymus_physiology0.95104574
111MP0001984_abnormal_olfaction0.95042755
112MP0002796_impaired_skin_barrier0.93557790
113MP0004808_abnormal_hematopoietic_stem0.93497569
114MP0004924_abnormal_behavior0.93185677
115MP0005386_behavior/neurological_phenoty0.93185677
116MP0000751_myopathy0.92609761
117MP0002452_abnormal_antigen_presenting0.92534121
118MP0003656_abnormal_erythrocyte_physiolo0.90268114
119MP0001348_abnormal_lacrimal_gland0.89968152
120MP0002752_abnormal_somatic_nervous0.89737008
121MP0000716_abnormal_immune_system0.89609659
122MP0001905_abnormal_dopamine_level0.88531715
123MP0003172_abnormal_lysosome_physiology0.87368133
124MP0005171_absent_coat_pigmentation0.86968957
125MP0000733_abnormal_muscle_development0.86775588
126MP0002429_abnormal_blood_cell0.86736594
127MP0003300_gastrointestinal_ulcer0.86617865
128MP0000759_abnormal_skeletal_muscle0.86152034
129MP0003075_altered_response_to0.85817691
130MP0000703_abnormal_thymus_morphology0.85674739
131MP0005670_abnormal_white_adipose0.84890578
132MP0001800_abnormal_humoral_immune0.84838087
133MP0001963_abnormal_hearing_physiology0.84492094
134MP0002132_abnormal_respiratory_system0.84357222
135MP0009931_abnormal_skin_appearance0.83671538
136MP0005464_abnormal_platelet_physiology0.82443852
137MP0002933_joint_inflammation0.81720645
138MP0002932_abnormal_joint_morphology0.81526064
139MP0000767_abnormal_smooth_muscle0.81316931
140MP0009780_abnormal_chondrocyte_physiolo0.80595849
141MP0002069_abnormal_eating/drinking_beha0.79348420
142MP0003633_abnormal_nervous_system0.78971522
143MP0001188_hyperpigmentation0.78414035
144MP0002229_neurodegeneration0.78262013
145MP0005075_abnormal_melanosome_morpholog0.76643595
146MP0002722_abnormal_immune_system0.76532222
147MP0003634_abnormal_glial_cell0.76051577
148MP0008874_decreased_physiological_sensi0.75929008
149MP0003861_abnormal_nervous_system0.75750680
150MP0002234_abnormal_pharynx_morphology0.75568311
151MP0000747_muscle_weakness0.75447807
152MP0000566_synostosis0.74908959
153MP0005671_abnormal_response_to0.74769525
154MP0000678_abnormal_parathyroid_gland0.74330087
155MP0002405_respiratory_system_inflammati0.74269225
156MP0003303_peritoneal_inflammation0.73781797
157MP0009785_altered_susceptibility_to0.73631004
158MP0005409_darkened_coat_color0.73243094
159MP0005377_hearing/vestibular/ear_phenot0.72068590
160MP0003878_abnormal_ear_physiology0.72068590
161MP0003091_abnormal_cell_migration0.70994578
162MP0005166_decreased_susceptibility_to0.70905918
163MP0000343_altered_response_to0.70829551
164MP0010768_mortality/aging0.70491477
165MP0002148_abnormal_hypersensitivity_rea0.70092540
166MP0010769_abnormal_survival0.69427825
167MP0000026_abnormal_inner_ear0.68615946
168MP0008877_abnormal_DNA_methylation0.67884528
169MP0000613_abnormal_salivary_gland0.67468732
170MP0000383_abnormal_hair_follicle0.67362725
171MP0006276_abnormal_autonomic_nervous0.67333350
172MP0008770_decreased_survivor_rate0.65725167
173MP0000013_abnormal_adipose_tissue0.65383113
174MP0003866_abnormal_defecation0.65252894
175MP0003631_nervous_system_phenotype0.64412406
176MP0000631_abnormal_neuroendocrine_gland0.63957158
177MP0000467_abnormal_esophagus_morphology0.63427983
178MP0005410_abnormal_fertilization0.62904599
179MP0003453_abnormal_keratinocyte_physiol0.62247375

Predicted human phenotypes

RankGene SetZ-score
1Myokymia (HP:0002411)5.26027781
2Focal motor seizures (HP:0011153)4.26399867
3Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)3.74144899
4Supranuclear gaze palsy (HP:0000605)3.73819030
5Progressive cerebellar ataxia (HP:0002073)3.71664012
6Visual hallucinations (HP:0002367)3.50244406
7Annular pancreas (HP:0001734)3.45277299
8Focal seizures (HP:0007359)3.38845796
9Axonal loss (HP:0003447)3.26340606
10Obstructive sleep apnea (HP:0002870)3.24316123
11Sleep apnea (HP:0010535)3.04196681
12Epileptic encephalopathy (HP:0200134)3.02601144
13Ankle clonus (HP:0011448)3.00363702
14Intestinal fistula (HP:0100819)2.93722062
15Ventricular fibrillation (HP:0001663)2.84807009
16Stridor (HP:0010307)2.76124841
17Broad face (HP:0000283)2.74126666
18Hyperacusis (HP:0010780)2.69174632
19Myopathic facies (HP:0002058)2.67394005
20Febrile seizures (HP:0002373)2.66214054
21Achilles tendon contracture (HP:0001771)2.65188494
22Eczematoid dermatitis (HP:0000976)2.65122777
23Abnormality of liposaccharide metabolism (HP:0010968)2.55888102
24Abnormality of glycosphingolipid metabolism (HP:0004343)2.55888102
25Abnormality of glycolipid metabolism (HP:0010969)2.55888102
26Elevated erythrocyte sedimentation rate (HP:0003565)2.55723620
27Ulnar bowing (HP:0003031)2.49859536
28Distal lower limb muscle weakness (HP:0009053)2.47232027
29Cellulitis (HP:0100658)2.45077149
30Cerebral aneurysm (HP:0004944)2.42746085
31Neurofibrillary tangles (HP:0002185)2.42602148
32Upper motor neuron abnormality (HP:0002127)2.40905867
33Peripheral hypomyelination (HP:0007182)2.40833924
34Atonic seizures (HP:0010819)2.40107188
35Abnormality of the Achilles tendon (HP:0005109)2.37022102
36Lip pit (HP:0100267)2.35257805
37Increased connective tissue (HP:0009025)2.34809470
38Upper limb amyotrophy (HP:0009129)2.32600475
39Distal upper limb amyotrophy (HP:0007149)2.32600475
40Abnormality of binocular vision (HP:0011514)2.31141075
41Diplopia (HP:0000651)2.31141075
42Chronic obstructive pulmonary disease (HP:0006510)2.27801862
43Obstructive lung disease (HP:0006536)2.27801862
44Vertebral compression fractures (HP:0002953)2.26316438
45Degeneration of the lateral corticospinal tracts (HP:0002314)2.25981614
46Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)2.25981614
47Long palpebral fissure (HP:0000637)2.25877494
48Reticulocytosis (HP:0001923)2.25422248
49Progressive external ophthalmoplegia (HP:0000590)2.25264162
50Personality changes (HP:0000751)2.24067328
51Recurrent bacterial skin infections (HP:0005406)2.23984141
52Milia (HP:0001056)2.22588513
53Abnormality of the aortic arch (HP:0012303)2.22471891
54Protrusio acetabuli (HP:0003179)2.21735208
55Thin bony cortex (HP:0002753)2.20305729
56Recurrent abscess formation (HP:0002722)2.20286440
57Centrally nucleated skeletal muscle fibers (HP:0003687)2.20169191
58Abnormality of the thoracic spine (HP:0100711)2.18205171
59Hypertensive crisis (HP:0100735)2.17013604
60Pointed chin (HP:0000307)2.13998960
61Polygenic inheritance (HP:0010982)2.10671306
62Disproportionate tall stature (HP:0001519)2.09294566
63Insomnia (HP:0100785)2.08160710
64Abnormality of macrophages (HP:0004311)2.07847596
65Mutism (HP:0002300)2.07362474
66Cerebral hypomyelination (HP:0006808)2.06689498
67Increased cerebral lipofuscin (HP:0011813)2.06296132
68Depression (HP:0000716)2.04290538
69Thoracic kyphosis (HP:0002942)2.03863787
70Gastrointestinal infarctions (HP:0005244)2.03387472
71Hyperthyroidism (HP:0000836)2.03305810
72Abnormal eating behavior (HP:0100738)2.02263645
73Broad distal phalanx of finger (HP:0009836)2.01352900
74Biconcave vertebral bodies (HP:0004586)2.01069060
75Easy fatigability (HP:0003388)2.00430436
76Dysmetria (HP:0001310)2.00116155
77Trismus (HP:0000211)1.99797537
78Cerebral inclusion bodies (HP:0100314)1.98417667
79Dialeptic seizures (HP:0011146)1.98367813
80Increased IgE level (HP:0003212)1.97712019
81Hemorrhage of the eye (HP:0011885)1.96167496
82Hypertriglyceridemia (HP:0002155)1.94548351
83Bulbar palsy (HP:0001283)1.94360710
84Dysphonia (HP:0001618)1.93868632
85Stereotypic behavior (HP:0000733)1.93695940
86Distal lower limb amyotrophy (HP:0008944)1.93402220
87Lower limb amyotrophy (HP:0007210)1.93394489
88Megalencephaly (HP:0001355)1.93267723
89Sparse lateral eyebrow (HP:0005338)1.92779521
90Absence seizures (HP:0002121)1.92731021
91Increased serum ferritin (HP:0003281)1.92062199
92Mitral regurgitation (HP:0001653)1.91751627
93Abnormality of the columella (HP:0009929)1.91745133
94Carpal bone hypoplasia (HP:0001498)1.91510084
95Increased neuronal autofluorescent lipopigment (HP:0002074)1.90754400
96Increased variability in muscle fiber diameter (HP:0003557)1.90704570
97Mediastinal lymphadenopathy (HP:0100721)1.89865161
98Ragged-red muscle fibers (HP:0003200)1.89362103
99Amblyopia (HP:0000646)1.88513585
100Abnormality of the fingertips (HP:0001211)1.87484417
101Parakeratosis (HP:0001036)1.87346958
102Segmental peripheral demyelination/remyelination (HP:0003481)1.86562121
103Genetic anticipation (HP:0003743)1.85415720
104Abnormality of the corticospinal tract (HP:0002492)1.85381085
105Pathologic fracture (HP:0002756)1.85044988
106Abnormal gallbladder physiology (HP:0012438)1.84164903
107Cholecystitis (HP:0001082)1.84164903
108Nuclear cataract (HP:0100018)1.83710474
109Hypochromic anemia (HP:0001931)1.83463448
110Neuronal loss in central nervous system (HP:0002529)1.82493291
111Genu recurvatum (HP:0002816)1.81632569
112Generalized tonic-clonic seizures (HP:0002069)1.81451977
113Torticollis (HP:0000473)1.79238853
114Urinary urgency (HP:0000012)1.79110233
115Gastrointestinal inflammation (HP:0004386)1.78565274
116Cervical subluxation (HP:0003308)1.78464984
117Hyperparathyroidism (HP:0000843)1.76574954
118Postural instability (HP:0002172)1.76288133
119Slow saccadic eye movements (HP:0000514)1.75806015
120Abnormality of skeletal muscle fiber size (HP:0012084)1.75468542
121Deep venous thrombosis (HP:0002625)1.75355995
122Abnormal EKG (HP:0003115)1.74999881
123Anal stenosis (HP:0002025)1.74935982
124Hemiparesis (HP:0001269)1.74528587
125Myositis (HP:0100614)1.74056616
126Split foot (HP:0001839)1.73918110
127Emphysema (HP:0002097)1.73138801
128Progressive sensorineural hearing impairment (HP:0000408)1.73055506
129Rapidly progressive (HP:0003678)1.72611033
130Onion bulb formation (HP:0003383)1.71605744
131Fragile skin (HP:0001030)1.71151591
132Shallow orbits (HP:0000586)1.71093500
133Rectal prolapse (HP:0002035)1.69781637
134Fragile nails (HP:0001808)1.69404894
135Diminished motivation (HP:0000745)1.68776430
136Deep palmar crease (HP:0006191)1.68245561
137Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)1.68179442
138Joint stiffness (HP:0001387)1.68148932
139Atelectasis (HP:0100750)1.68096072
140Neoplasm of the heart (HP:0100544)1.67704840
141Spastic gait (HP:0002064)1.67614503
142Rectovaginal fistula (HP:0000143)1.67600713
143Rectal fistula (HP:0100590)1.67600713
144Focal dystonia (HP:0004373)1.67382316
145Round ear (HP:0100830)1.66841359
146Purpura (HP:0000979)1.66654787
147Lymphangioma (HP:0100764)1.66500921
148Limb dystonia (HP:0002451)1.66133824
149Mask-like facies (HP:0000298)1.66122107
150Concave nail (HP:0001598)1.65867862
151Progressive hearing impairment (HP:0001730)1.65505446
152Bowel incontinence (HP:0002607)1.64961666
153Hypercortisolism (HP:0001578)1.64647390
154Abnormal auditory evoked potentials (HP:0006958)1.63584533
155Anxiety (HP:0000739)1.62697157
156Iris hypopigmentation (HP:0007730)1.62508721
157Truncus arteriosus (HP:0001660)1.62197412
158Testicular atrophy (HP:0000029)1.62040126
159Anomalous pulmonary venous return (HP:0010772)1.62003859
160Termporal pattern (HP:0011008)1.60757124
161Insidious onset (HP:0003587)1.60757124
162Unilateral renal agenesis (HP:0000122)1.60577553
163Delusions (HP:0000746)1.59506421
164Depressed nasal tip (HP:0000437)1.59463865
165Action tremor (HP:0002345)1.57670405
166External ophthalmoplegia (HP:0000544)1.56558152
167Poor eye contact (HP:0000817)1.56146129
168Ocular albinism (HP:0001107)1.54850158
169Macroglossia (HP:0000158)1.54473174
170Aplasia/Hypoplasia involving the carpal bones (HP:0006502)1.53770208
171Palpebral edema (HP:0100540)1.53414305
172Upper limb muscle weakness (HP:0003484)1.52479486
173Dysostosis multiplex (HP:0000943)1.52421517
174J-shaped sella turcica (HP:0002680)1.52360768
175Urinary bladder sphincter dysfunction (HP:0002839)1.51741694
176Spinal canal stenosis (HP:0003416)1.49016770
177Generalized hypotonia (HP:0001290)1.48997358
178Broad alveolar ridges (HP:0000187)1.48861826
179Abnormality of dental color (HP:0011073)1.48064015

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TRIB34.27897537
2EPHA43.61565977
3ERN13.45120319
4SIK13.29915537
5SMG12.93525385
6MAPK152.92406106
7CDK192.71506873
8MAP3K92.50127609
9PRPF4B2.45440734
10NME22.43126968
11NTRK32.25159244
12PRKD32.23676374
13UHMK12.15817247
14EPHA22.08503605
15MAP3K112.08081402
16MAP2K32.06566226
17PRKD22.05893235
18TAOK21.93361242
19TESK21.89459457
20DAPK21.83815360
21PAK61.80559564
22MAP4K11.79486401
23BUB11.78384406
24CDK121.75015732
25RIPK11.66594160
26MARK11.65001158
27MAPKAPK51.61005270
28TAOK11.60989853
29MINK11.59678034
30MAP2K21.57779645
31DMPK1.50510550
32SIK21.43832793
33NTRK21.43053485
34MARK21.42787420
35PNCK1.37976210
36HIPK21.36339805
37IRAK41.34871145
38STK381.31676981
39CAMK11.30428444
40PKN21.29995724
41STK111.28975919
42MAP3K31.27923329
43GRK61.27833084
44KSR21.27739041
45ARAF1.25693466
46TNK21.24301642
47TTN1.21010832
48MAP3K11.17760186
49RIPK41.16585175
50SIK31.12452206
51NTRK11.12423082
52PIM21.10436854
53TBK11.05650017
54CDK51.04410388
55NME11.02041335
56ICK1.00847328
57DAPK11.00221547
58CLK10.98484873
59RPS6KA20.98123201
60PRKCH0.96251736
61ALK0.95604337
62FGFR40.95353365
63KDR0.93475337
64MAP3K100.92645493
65FES0.92636644
66TYRO30.92101460
67PDPK10.90801786
68MTOR0.90724612
69TESK10.90695575
70IRAK20.89289081
71SGK2230.88368390
72SGK4940.88368390
73MAPK120.88210117
74PTK60.87867035
75CAMKK10.86725715
76BRAF0.82777907
77CDK180.76931898
78CDK150.76642131
79BMX0.76403598
80CDK11A0.75733154
81CAMK2B0.74781593
82CAMK40.74781078
83CDK140.72901401
84IRAK30.71337024
85CDC42BPA0.71314551
86DYRK30.71070884
87DYRK1B0.71037809
88LIMK10.70749691
89RPS6KA60.68719221
90MAPKAPK30.68659472
91MAP3K130.67600726
92RPS6KA40.67010892
93MAP3K60.66935236
94PRKG20.65803009
95RPS6KC10.65674195
96RPS6KL10.65674195
97TLK10.64938248
98PKN10.63490908
99RAF10.60926338
100PRKCG0.60683107
101LRRK20.60042377
102PRKD10.59822791
103TYK20.59722972
104CAMK1D0.59035916
105ZAP700.58751681
106RPS6KA50.58710955
107MAP2K60.58635075
108DAPK30.58377708
109KSR10.57822025
110TNIK0.57060970
111MAP3K80.56939739
112PINK10.56518680
113PAK40.56429884
114RPS6KB20.55863073
115CAMK2D0.55713607
116PDK10.55263041
117RPS6KA10.54816371
118BRSK10.53133206
119CAMK2G0.52939760
120IKBKE0.52465654
121SYK0.52351595
122CSK0.52209076
123CDK40.52204284
124CAMK2A0.52001639
125OXSR10.51775982
126BCKDK0.51589983
127EPHB10.49967652
128PRKCZ0.49540170
129BLK0.47969933
130JAK30.47846001
131AURKA0.47791426
132EEF2K0.47690037
133MAPK110.47160815
134PAK30.46489117
135DDR20.45553460
136PTK20.45515004
137PLK20.45067822
138MATK0.44941735
139MAP3K70.44856727
140MAPK100.44634615
141SGK10.44079915
142LATS20.44019135
143MAPK70.43941524
144SGK20.40894808
145FGR0.40876398
146MAPK40.39089647
147BTK0.38879877
148SCYL20.38689816
149IKBKB0.38069636
150PDGFRA0.37785679
151MARK30.36284911
152HCK0.34680960
153CHUK0.34578217
154ABL20.33983392
155CDK70.33624115

Predicted pathways (KEGG)

RankGene SetZ-score
1Sulfur relay system_Homo sapiens_hsa041222.70282172
2Other glycan degradation_Homo sapiens_hsa005112.50133404
3Synaptic vesicle cycle_Homo sapiens_hsa047212.42118411
4Amphetamine addiction_Homo sapiens_hsa050312.22800811
5Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005322.22789958
6Olfactory transduction_Homo sapiens_hsa047402.17980373
7Nicotine addiction_Homo sapiens_hsa050332.14284661
8Circadian entrainment_Homo sapiens_hsa047132.08431964
9Cocaine addiction_Homo sapiens_hsa050301.95710951
10Long-term potentiation_Homo sapiens_hsa047201.92005605
11Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.88333187
12Bladder cancer_Homo sapiens_hsa052191.84143420
13Chronic myeloid leukemia_Homo sapiens_hsa052201.79500214
14Glutamatergic synapse_Homo sapiens_hsa047241.76449699
15Insulin secretion_Homo sapiens_hsa049111.74955429
16Morphine addiction_Homo sapiens_hsa050321.73848650
17Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.65503285
18Salivary secretion_Homo sapiens_hsa049701.63731279
19Dopaminergic synapse_Homo sapiens_hsa047281.61002805
20Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.56994696
21GABAergic synapse_Homo sapiens_hsa047271.55854327
22Aldosterone synthesis and secretion_Homo sapiens_hsa049251.51195178
23Gastric acid secretion_Homo sapiens_hsa049711.49385005
24Cholinergic synapse_Homo sapiens_hsa047251.46351492
25Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.46349413
26Toll-like receptor signaling pathway_Homo sapiens_hsa046201.44784201
27Oxytocin signaling pathway_Homo sapiens_hsa049211.39447589
28Phosphatidylinositol signaling system_Homo sapiens_hsa040701.36678589
29Central carbon metabolism in cancer_Homo sapiens_hsa052301.35640550
30Glycosaminoglycan degradation_Homo sapiens_hsa005311.33200650
31Fructose and mannose metabolism_Homo sapiens_hsa000511.31989480
32Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.28090596
33GnRH signaling pathway_Homo sapiens_hsa049121.24283762
34Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.24218186
35Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.23753130
36Taste transduction_Homo sapiens_hsa047421.23604750
37Long-term depression_Homo sapiens_hsa047301.23100539
38Calcium signaling pathway_Homo sapiens_hsa040201.22541043
39Melanogenesis_Homo sapiens_hsa049161.22205252
40Pancreatic cancer_Homo sapiens_hsa052121.21507545
41VEGF signaling pathway_Homo sapiens_hsa043701.20256172
42Pentose phosphate pathway_Homo sapiens_hsa000301.19834003
43Serotonergic synapse_Homo sapiens_hsa047261.19513352
44Estrogen signaling pathway_Homo sapiens_hsa049151.17353698
45mTOR signaling pathway_Homo sapiens_hsa041501.16200694
46Insulin signaling pathway_Homo sapiens_hsa049101.14668894
47Cyanoamino acid metabolism_Homo sapiens_hsa004601.13784545
48ErbB signaling pathway_Homo sapiens_hsa040121.13400239
49Leishmaniasis_Homo sapiens_hsa051401.12692526
50Hepatitis C_Homo sapiens_hsa051601.12083853
51Renin secretion_Homo sapiens_hsa049241.11054175
52T cell receptor signaling pathway_Homo sapiens_hsa046601.07783121
53TNF signaling pathway_Homo sapiens_hsa046681.07733233
54Endocytosis_Homo sapiens_hsa041441.07434140
55Axon guidance_Homo sapiens_hsa043601.06326524
56cAMP signaling pathway_Homo sapiens_hsa040241.04305133
57Malaria_Homo sapiens_hsa051441.03243409
58Tuberculosis_Homo sapiens_hsa051521.02570281
59Leukocyte transendothelial migration_Homo sapiens_hsa046701.01032816
60MAPK signaling pathway_Homo sapiens_hsa040101.00825509
61Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.99991622
62Adipocytokine signaling pathway_Homo sapiens_hsa049200.99790132
63Wnt signaling pathway_Homo sapiens_hsa043100.98993026
64Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.98970755
65Phospholipase D signaling pathway_Homo sapiens_hsa040720.98691311
66Galactose metabolism_Homo sapiens_hsa000520.97138264
67Lysosome_Homo sapiens_hsa041420.96716462
68Influenza A_Homo sapiens_hsa051640.96531964
69Glycerophospholipid metabolism_Homo sapiens_hsa005640.96417767
70Notch signaling pathway_Homo sapiens_hsa043300.94777321
71Apoptosis_Homo sapiens_hsa042100.94496752
72Choline metabolism in cancer_Homo sapiens_hsa052310.93713026
73Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.93392553
74Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.93209731
75Circadian rhythm_Homo sapiens_hsa047100.92450878
76Gap junction_Homo sapiens_hsa045400.92254851
77Hepatitis B_Homo sapiens_hsa051610.91242155
78Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.90692806
79AMPK signaling pathway_Homo sapiens_hsa041520.89863160
80Neurotrophin signaling pathway_Homo sapiens_hsa047220.89658097
81Inositol phosphate metabolism_Homo sapiens_hsa005620.89631757
82Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.85885662
83Renal cell carcinoma_Homo sapiens_hsa052110.84947652
84B cell receptor signaling pathway_Homo sapiens_hsa046620.84722742
85Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.84178696
86Dorso-ventral axis formation_Homo sapiens_hsa043200.83981569
87Thyroid cancer_Homo sapiens_hsa052160.83395085
88NF-kappa B signaling pathway_Homo sapiens_hsa040640.83326002
89Pancreatic secretion_Homo sapiens_hsa049720.82282248
90Hedgehog signaling pathway_Homo sapiens_hsa043400.81808313
91Oocyte meiosis_Homo sapiens_hsa041140.81684089
92Toxoplasmosis_Homo sapiens_hsa051450.81431856
93Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.81431077
94Glioma_Homo sapiens_hsa052140.80701820
95Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.79535054
96AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.79200605
97Type II diabetes mellitus_Homo sapiens_hsa049300.78537372
98Cardiac muscle contraction_Homo sapiens_hsa042600.78340185
99Ribosome_Homo sapiens_hsa030100.78012358
100Sphingolipid signaling pathway_Homo sapiens_hsa040710.77970864
101Colorectal cancer_Homo sapiens_hsa052100.77720370
102Insulin resistance_Homo sapiens_hsa049310.76946981
103cGMP-PKG signaling pathway_Homo sapiens_hsa040220.76895063
104Vascular smooth muscle contraction_Homo sapiens_hsa042700.75512050
105Rap1 signaling pathway_Homo sapiens_hsa040150.75445993
106Collecting duct acid secretion_Homo sapiens_hsa049660.75414588
107Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.74294722
108Vibrio cholerae infection_Homo sapiens_hsa051100.73873456
109Acute myeloid leukemia_Homo sapiens_hsa052210.73082074
110Basal cell carcinoma_Homo sapiens_hsa052170.72665651
111Salmonella infection_Homo sapiens_hsa051320.71468013
112Non-small cell lung cancer_Homo sapiens_hsa052230.70400206
113Amoebiasis_Homo sapiens_hsa051460.70231601
114Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.70150257
115Herpes simplex infection_Homo sapiens_hsa051680.69798577
116Endometrial cancer_Homo sapiens_hsa052130.68266669
117Prion diseases_Homo sapiens_hsa050200.68045048
118Ras signaling pathway_Homo sapiens_hsa040140.67477818
119RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.67421897
120Thyroid hormone signaling pathway_Homo sapiens_hsa049190.65675754
121Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.65408843
122Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.63634220
123Primary immunodeficiency_Homo sapiens_hsa053400.63603052
124Carbohydrate digestion and absorption_Homo sapiens_hsa049730.62500687
125HIF-1 signaling pathway_Homo sapiens_hsa040660.61880032
126Biosynthesis of amino acids_Homo sapiens_hsa012300.60877112
127Alcoholism_Homo sapiens_hsa050340.59901022
128Dilated cardiomyopathy_Homo sapiens_hsa054140.59253941
129Longevity regulating pathway - mammal_Homo sapiens_hsa042110.58601802
130Hippo signaling pathway_Homo sapiens_hsa043900.58517522
131Phenylalanine metabolism_Homo sapiens_hsa003600.57481194
132Regulation of actin cytoskeleton_Homo sapiens_hsa048100.57388840
133Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.56319969
134Focal adhesion_Homo sapiens_hsa045100.55418339
135Chemokine signaling pathway_Homo sapiens_hsa040620.54988943
136Viral myocarditis_Homo sapiens_hsa054160.52846350
137mRNA surveillance pathway_Homo sapiens_hsa030150.52511840
138Viral carcinogenesis_Homo sapiens_hsa052030.52335607
139Epstein-Barr virus infection_Homo sapiens_hsa051690.52169629
140Thyroid hormone synthesis_Homo sapiens_hsa049180.51085358
141Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.51044381
142Shigellosis_Homo sapiens_hsa051310.50350622
143Tight junction_Homo sapiens_hsa045300.50059564
144Osteoclast differentiation_Homo sapiens_hsa043800.49733279
145Prolactin signaling pathway_Homo sapiens_hsa049170.49602987
146Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.48293660
147Pertussis_Homo sapiens_hsa051330.47425631
148Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.47302685
149HTLV-I infection_Homo sapiens_hsa051660.46347427
150Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.46151641
151FoxO signaling pathway_Homo sapiens_hsa040680.46099519
152Prostate cancer_Homo sapiens_hsa052150.45356730
153Proteoglycans in cancer_Homo sapiens_hsa052050.42609039
154Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.41597198

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »