UBAP2L

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1Golgi transport vesicle coating (GO:0048200)5.71097268
2COPI coating of Golgi vesicle (GO:0048205)5.71097268
3nuclear pore complex assembly (GO:0051292)4.58065304
4spliceosomal tri-snRNP complex assembly (GO:0000244)4.48892704
5mitotic sister chromatid cohesion (GO:0007064)4.46426854
6nuclear pore organization (GO:0006999)4.29687600
7regulation of nucleobase-containing compound transport (GO:0032239)3.95695226
8retrograde vesicle-mediated transport, Golgi to ER (GO:0006890)3.84857112
9regulation of histone H3-K27 methylation (GO:0061085)3.83042632
10maintenance of protein localization in endoplasmic reticulum (GO:0035437)3.57009662
11pore complex assembly (GO:0046931)3.56198838
12regulation of NFAT protein import into nucleus (GO:0051532)3.53811975
13regulation of mammary gland epithelial cell proliferation (GO:0033599)3.53600638
14DNA unwinding involved in DNA replication (GO:0006268)3.49052593
15regulation of DNA endoreduplication (GO:0032875)3.47615720
16protein export from nucleus (GO:0006611)3.46450002
17peptidyl-arginine omega-N-methylation (GO:0035247)3.41239145
18mitotic nuclear envelope disassembly (GO:0007077)3.38353657
19protein retention in ER lumen (GO:0006621)3.38091474
20pre-miRNA processing (GO:0031054)3.34838831
21protein localization to kinetochore (GO:0034501)3.29864882
22protein complex localization (GO:0031503)3.26594878
23COPII vesicle coating (GO:0048208)3.21160060
24cellular protein complex localization (GO:0034629)3.17655327
25negative regulation of mRNA splicing, via spliceosome (GO:0048025)3.15274296
26vesicle coating (GO:0006901)3.11430690
27membrane disassembly (GO:0030397)3.10980158
28nuclear envelope disassembly (GO:0051081)3.10980158
29kinetochore organization (GO:0051383)3.10733672
30formation of translation preinitiation complex (GO:0001731)3.10026767
31adherens junction assembly (GO:0034333)3.09380071
32glucocorticoid receptor signaling pathway (GO:0042921)3.03134133
33planar cell polarity pathway involved in neural tube closure (GO:0090179)3.02715169
34heterochromatin organization (GO:0070828)3.01097203
35proline biosynthetic process (GO:0006561)2.98308432
36negative regulation of RNA splicing (GO:0033119)2.97428464
37DNA duplex unwinding (GO:0032508)2.96873212
38chromosome condensation (GO:0030261)2.96476848
39DNA geometric change (GO:0032392)2.95632323
40regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)2.93911808
41cell-substrate adherens junction assembly (GO:0007045)2.92732495
42focal adhesion assembly (GO:0048041)2.92732495
43activation of signaling protein activity involved in unfolded protein response (GO:0006987)2.92072820
44regulation of chromatin binding (GO:0035561)2.90431825
45positive regulation of nuclease activity (GO:0032075)2.88255856
46stress granule assembly (GO:0034063)2.88249911
47peptidyl-arginine methylation (GO:0018216)2.88212690
48peptidyl-arginine N-methylation (GO:0035246)2.88212690
49protein localization to chromosome, centromeric region (GO:0071459)2.86952042
50negative regulation of histone methylation (GO:0031061)2.85276649
51histone H2B ubiquitination (GO:0033523)2.83819868
52regulation of RNA export from nucleus (GO:0046831)2.83156856
53activation of Rac GTPase activity (GO:0032863)2.82699472
54dosage compensation (GO:0007549)2.82279118
55negative regulation of cell size (GO:0045792)2.81229569
56intracellular estrogen receptor signaling pathway (GO:0030520)2.81139022
57histone H3-K4 trimethylation (GO:0080182)2.79654111
58regulation of mitotic spindle organization (GO:0060236)2.79301517
59regulation of spindle organization (GO:0090224)2.78847081
60sister chromatid segregation (GO:0000819)2.77385883
61mitotic chromosome condensation (GO:0007076)2.77312682
62establishment of integrated proviral latency (GO:0075713)2.76270840
63mRNA stabilization (GO:0048255)2.75724645
64RNA stabilization (GO:0043489)2.75724645
65IMP biosynthetic process (GO:0006188)2.73826741
66regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450912.73670274
67cytoplasmic mRNA processing body assembly (GO:0033962)2.72405951
68regulation of stem cell maintenance (GO:2000036)2.71995475
69kinetochore assembly (GO:0051382)2.71652426
70negative regulation of mRNA processing (GO:0050686)2.71345247
71histone arginine methylation (GO:0034969)2.70974995
72pentose-phosphate shunt (GO:0006098)2.67955132
73endoplasmic reticulum unfolded protein response (GO:0030968)2.63824404
74regulation of histone H3-K9 methylation (GO:0051570)2.62358001
75DNA packaging (GO:0006323)2.62200340
76paraxial mesoderm development (GO:0048339)2.61858205
77histone H3-K4 methylation (GO:0051568)2.61243898
78histone H3-K9 methylation (GO:0051567)2.60923547
79folic acid-containing compound biosynthetic process (GO:0009396)2.60493784
80regulation of nuclease activity (GO:0032069)2.59407626
81regulation of translational termination (GO:0006449)2.58345985
82positive regulation of DNA-templated transcription, elongation (GO:0032786)2.57860643
83positive regulation of transcription from RNA polymerase III promoter (GO:0045945)2.57610968
84mitotic sister chromatid segregation (GO:0000070)2.57469517
85ER-nucleus signaling pathway (GO:0006984)2.56557484
86DNA strand elongation involved in DNA replication (GO:0006271)2.56258217
87mitotic recombination (GO:0006312)2.56064331
88histone mRNA catabolic process (GO:0071044)2.56029870
89basement membrane organization (GO:0071711)2.55426382
90peptidyl-lysine dimethylation (GO:0018027)2.55359673
91alternative mRNA splicing, via spliceosome (GO:0000380)2.54648604
92positive regulation of chromosome segregation (GO:0051984)2.54029240
93protein localization to microtubule (GO:0035372)2.53532642
94ribosome assembly (GO:0042255)2.53067977
95cellular response to epidermal growth factor stimulus (GO:0071364)2.52646079
96DNA conformation change (GO:0071103)2.51596872
97negative regulation of mRNA metabolic process (GO:1903312)2.51379653
98snRNA processing (GO:0016180)2.50568216
99histone H3-K36 demethylation (GO:0070544)2.50418263
100regulation of translational fidelity (GO:0006450)2.50261542
101maternal placenta development (GO:0001893)2.50137084
102negative regulation of DNA-dependent DNA replication (GO:2000104)2.50065889
103corticosteroid receptor signaling pathway (GO:0031958)2.49341163
104mitotic metaphase plate congression (GO:0007080)2.49031108
105DNA topological change (GO:0006265)2.48329418
106positive regulation of DNA-dependent DNA replication (GO:2000105)2.47800279
107peptidyl-lysine trimethylation (GO:0018023)2.47755103
108sister chromatid cohesion (GO:0007062)2.47609254
109viral mRNA export from host cell nucleus (GO:0046784)2.47328968
110DNA strand elongation (GO:0022616)2.46982205
111regulation of nuclear cell cycle DNA replication (GO:0033262)2.46590212
112NADPH regeneration (GO:0006740)2.44271192
113RNA localization (GO:0006403)2.43901860
1143-UTR-mediated mRNA stabilization (GO:0070935)2.43861085
115metaphase plate congression (GO:0051310)2.42844002
116positive regulation of gene expression, epigenetic (GO:0045815)2.41344780
117snRNA metabolic process (GO:0016073)2.41195898
118nuclear-transcribed mRNA poly(A) tail shortening (GO:0000289)2.40835805
119translesion synthesis (GO:0019985)2.40813605
120NLS-bearing protein import into nucleus (GO:0006607)2.40386644
121meiotic chromosome segregation (GO:0045132)2.40005137
122regulation of telomere maintenance (GO:0032204)2.39788830
123histone H4-K12 acetylation (GO:0043983)2.38910908
124DNA replication initiation (GO:0006270)2.38247521
125protein localization to chromosome (GO:0034502)2.37856532
126nuclear envelope organization (GO:0006998)2.37575432
127chromatin assembly (GO:0031497)2.36813107
128regulation of histone H3-K4 methylation (GO:0051569)2.36586047
129regulation of DNA damage checkpoint (GO:2000001)2.34711941
130chromatin assembly or disassembly (GO:0006333)2.33960040
131ATP-dependent chromatin remodeling (GO:0043044)2.33371022
132telomere maintenance via semi-conservative replication (GO:0032201)2.33300614
133positive regulation of histone H3-K4 methylation (GO:0051571)2.33146400
134positive regulation of mitotic metaphase/anaphase transition (GO:0045842)2.32962301
135positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)2.32962301
136positive regulation of mitotic sister chromatid separation (GO:1901970)2.32962301
137telomere maintenance via telomerase (GO:0007004)2.32346990
138protein-DNA complex disassembly (GO:0032986)2.31154428
139nucleosome disassembly (GO:0006337)2.31154428
140mRNA transport (GO:0051028)2.31012714
141histone lysine methylation (GO:0034968)2.30875856
142regulation of mRNA stability (GO:0043488)2.29475485
143telomere maintenance via telomere lengthening (GO:0010833)2.27856474
144histone H2A acetylation (GO:0043968)2.27424488
145positive regulation of SMAD protein import into nucleus (GO:0060391)2.25591037
146DNA replication-independent nucleosome assembly (GO:0006336)2.25352293
147DNA replication-independent nucleosome organization (GO:0034724)2.25352293
148telomere maintenance via recombination (GO:0000722)2.25265012
149histone H3-K9 modification (GO:0061647)2.25118497
150gene silencing by RNA (GO:0031047)2.24422430
151spindle assembly checkpoint (GO:0071173)2.24099667
152RNA splicing, via transesterification reactions with bulged adenosine as nucleophile (GO:0000377)2.23414010
153mRNA splicing, via spliceosome (GO:0000398)2.23414010
154establishment of chromosome localization (GO:0051303)2.23043236
155RNA splicing, via transesterification reactions (GO:0000375)2.22810267
156regulation of mitotic metaphase/anaphase transition (GO:0030071)2.21209950

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human9.90696535
2FOXM1_23109430_ChIP-Seq_U2OS_Human5.18691242
3EGR1_19374776_ChIP-ChIP_THP-1_Human4.92903916
4E2F4_17652178_ChIP-ChIP_JURKAT_Human3.71506517
5MYC_22102868_ChIP-Seq_BL_Human3.26200189
6FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human3.11128104
7TP63_19390658_ChIP-ChIP_HaCaT_Human3.03128401
8* KDM5B_21448134_ChIP-Seq_MESCs_Mouse2.64984089
9NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.62264785
10MYC_18555785_ChIP-Seq_MESCs_Mouse2.60885381
11E2F1_21310950_ChIP-Seq_MCF-7_Human2.40502253
12RBPJ_22232070_ChIP-Seq_NCS_Mouse2.15203642
13CIITA_25753668_ChIP-Seq_RAJI_Human2.13778193
14STAT6_20620947_ChIP-Seq_CD4_POS_T_Human2.13435223
15FOXP3_17237761_ChIP-ChIP_TREG_Mouse2.09504240
16ZNF263_19887448_ChIP-Seq_K562_Human2.03048906
17VDR_21846776_ChIP-Seq_THP-1_Human1.97788394
18* EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.97001321
19MYC_19079543_ChIP-ChIP_MESCs_Mouse1.95388980
20SCL_19346495_ChIP-Seq_HPC-7_Human1.89176044
21ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.89146464
22* CLOCK_20551151_ChIP-Seq_293T_Human1.86550878
23TP63_17297297_ChIP-ChIP_HaCaT_Human1.83881825
24SALL1_21062744_ChIP-ChIP_HESCs_Human1.79527048
25MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.76036481
26* MYC_19030024_ChIP-ChIP_MESCs_Mouse1.70520336
27* RACK7_27058665_Chip-Seq_MCF-7_Human1.65435903
28HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.65012109
29YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.64442276
30TCF7_22412390_ChIP-Seq_EML_Mouse1.64144255
31THAP11_20581084_ChIP-Seq_MESCs_Mouse1.63944780
32* MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.63366683
33NELFA_20434984_ChIP-Seq_ESCs_Mouse1.61563598
34KLF4_18555785_ChIP-Seq_MESCs_Mouse1.59720501
35ELF1_17652178_ChIP-ChIP_JURKAT_Human1.58360976
36AR_21909140_ChIP-Seq_LNCAP_Human1.57990168
37* SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.51408306
38* P300_27058665_Chip-Seq_ZR-75-30cells_Human1.48965952
39* XRN2_22483619_ChIP-Seq_HELA_Human1.45498832
40MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.43502835
41* ZFP281_18757296_ChIP-ChIP_E14_Mouse1.42954352
42TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.41036338
43MYCN_18555785_ChIP-Seq_MESCs_Mouse1.40736561
44DCP1A_22483619_ChIP-Seq_HELA_Human1.39383234
45EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.39233875
46LXR_22292898_ChIP-Seq_THP-1_Human1.38948558
47TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.38783478
48CREB1_15753290_ChIP-ChIP_HEK293T_Human1.38164035
49* WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.37401486
50SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.36083751
51UTX_26944678_Chip-Seq_JUKART_Human1.33878160
52MAF_26560356_Chip-Seq_TH1_Human1.33041266
53HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.32327352
54MYB_26560356_Chip-Seq_TH1_Human1.32202365
55MYB_26560356_Chip-Seq_TH2_Human1.32118290
56SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.31088835
57RARG_19884340_ChIP-ChIP_MEFs_Mouse1.30414499
58PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.30329272
59* KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.28165835
60NOTCH1_21737748_ChIP-Seq_TLL_Human1.26522109
61DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.25925124
62KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.24989103
63ESR1_15608294_ChIP-ChIP_MCF-7_Human1.24779230
64KDM2B_26808549_Chip-Seq_SUP-B15_Human1.23985475
65TFEB_21752829_ChIP-Seq_HELA_Human1.23747466
66STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.23004218
67FOXP3_21729870_ChIP-Seq_TREG_Human1.22528164
68* KDM5A_27292631_Chip-Seq_BREAST_Human1.22410818
69* CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.21964313
70ELK1_19687146_ChIP-ChIP_HELA_Human1.21921708
71KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.21042332
72* MYC_18358816_ChIP-ChIP_MESCs_Mouse1.20555018
73IRF8_22096565_ChIP-ChIP_GC-B_Human1.19940859
74* SPI1_23547873_ChIP-Seq_NB4_Human1.19727894
75HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse1.19608335
76CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.17621813
77EST1_17652178_ChIP-ChIP_JURKAT_Human1.17445840
78MYB_21317192_ChIP-Seq_ERMYB_Mouse1.17091527
79STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.16928605
80ATF3_27146783_Chip-Seq_COLON_Human1.16406699
81VDR_24763502_ChIP-Seq_THP-1_Human1.15946218
82FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.15732937
83STAT3_1855785_ChIP-Seq_MESCs_Mouse1.15009651
84KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.14997097
85GABP_19822575_ChIP-Seq_HepG2_Human1.13993207
86* NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.13931819
87* ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.13616400
88SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.13044218
89TTF2_22483619_ChIP-Seq_HELA_Human1.12915983
90* DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.12142212
91TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.11092018
92CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.10768882
93HIF1A_21447827_ChIP-Seq_MCF-7_Human1.10125634
94SREBP1_19666523_ChIP-Seq_LIVER_Mouse1.09772961
95* E2F1_18555785_ChIP-Seq_MESCs_Mouse1.09625987
96KDM2B_26808549_Chip-Seq_DND41_Human1.09605871
97* ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.08380119
98HOXB4_20404135_ChIP-ChIP_EML_Mouse1.08186555
99KDM2B_26808549_Chip-Seq_K562_Human1.07376592
100POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.07043664
101PKCTHETA_26484144_Chip-Seq_BREAST_Human1.06817497
102* UBF1/2_26484160_Chip-Seq_HMECs_Human1.06024346
103FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human1.05899209
104VDR_23849224_ChIP-Seq_CD4+_Human1.05053092
105JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.05023742
106NANOG_18555785_ChIP-Seq_MESCs_Mouse1.04651915
107IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.04066362
108ETS1_20019798_ChIP-Seq_JURKAT_Human1.03539519
109POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.03512143
110GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.03344918
111UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.03157946
112PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.02367253
113RUNX1_22412390_ChIP-Seq_EML_Mouse1.02320772
114E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.02262097
115BRD4_27068464_Chip-Seq_AML-cells_Mouse1.01215381
116NKX2-5_21415370_ChIP-Seq_HL-1_Mouse1.00157060
117HCFC1_20581084_ChIP-Seq_MESCs_Mouse0.99749279
118* TCF3_18467660_ChIP-ChIP_MESCs_Mouse0.98634645
119NOTCH1_17114293_ChIP-ChIP_T-ALL_Human0.97356736
120CREB1_26743006_Chip-Seq_LNCaP_Human0.97230619
121KDM2B_26808549_Chip-Seq_JURKAT_Human0.96908992
122* ZFX_18555785_ChIP-Seq_MESCs_Mouse0.96307971
123KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.95907193
124TFAP2C_20629094_ChIP-Seq_MCF-7_Human0.94982522
125DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.94403855
126ELK3_25401928_ChIP-Seq_HUVEC_Human0.94195604
127NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse0.93625440
128FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse0.93584208
129* BRD4_25478319_ChIP-Seq_HGPS_Human0.92808697
130PADI4_21655091_ChIP-ChIP_MCF-7_Human0.92377177
131ERG_20887958_ChIP-Seq_HPC-7_Mouse0.91626485
132NCOR1_26117541_ChIP-Seq_K562_Human0.90394134
133CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.90203291
134* SPI1_23127762_ChIP-Seq_K562_Human0.90124780
135ZFP281_27345836_Chip-Seq_ESCs_Mouse0.88271281
136KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human0.88167058
137* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.88064248
138* TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.87436470
139NANOG_21062744_ChIP-ChIP_HESCs_Human0.87199775
140CHD1_26751641_Chip-Seq_LNCaP_Human0.86550695
141PRDM5_23873026_ChIP-Seq_MEFs_Mouse0.84942242
142STAT6_21828071_ChIP-Seq_BEAS2B_Human0.84522659
143SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse0.83397687
144RUNX2_24764292_ChIP-Seq_MC3T3_Mouse0.81492765

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0010094_abnormal_chromosome_stability2.86139148
2MP0003111_abnormal_nucleus_morphology2.81519311
3MP0002396_abnormal_hematopoietic_system2.68898752
4MP0008057_abnormal_DNA_replication2.59517588
5MP0005451_abnormal_body_composition2.47127591
6MP0008007_abnormal_cellular_replicative2.45551564
7MP0003077_abnormal_cell_cycle2.43901458
8MP0005076_abnormal_cell_differentiation2.43595136
9MP0010352_gastrointestinal_tract_polyps2.36227036
10MP0003693_abnormal_embryo_hatching2.22287564
11MP0000569_abnormal_digit_pigmentation2.08440639
12MP0004808_abnormal_hematopoietic_stem2.03307721
13MP0010030_abnormal_orbit_morphology2.00486948
14MP0008058_abnormal_DNA_repair1.99995890
15MP0003121_genomic_imprinting1.92767543
16MP0004957_abnormal_blastocyst_morpholog1.91226101
17MP0005623_abnormal_meninges_morphology1.87169118
18MP0004185_abnormal_adipocyte_glucose1.83544720
19MP0004272_abnormal_basement_membrane1.82133478
20MP0003123_paternal_imprinting1.79400207
21MP0008877_abnormal_DNA_methylation1.77976095
22MP0002009_preneoplasia1.75540637
23MP0010307_abnormal_tumor_latency1.75315221
24MP0001849_ear_inflammation1.66039045
25MP0005367_renal/urinary_system_phenotyp1.64314994
26MP0000516_abnormal_urinary_system1.64314994
27MP0005409_darkened_coat_color1.60538536
28MP0000350_abnormal_cell_proliferation1.60310265
29MP0010234_abnormal_vibrissa_follicle1.53907028
30MP0004197_abnormal_fetal_growth/weight/1.53154381
31MP0006054_spinal_hemorrhage1.47191537
32MP0003984_embryonic_growth_retardation1.45439422
33MP0009278_abnormal_bone_marrow1.45364350
34MP0005380_embryogenesis_phenotype1.44829420
35MP0001672_abnormal_embryogenesis/_devel1.44829420
36MP0002088_abnormal_embryonic_growth/wei1.42809103
37MP0004858_abnormal_nervous_system1.41699326
38MP0003566_abnormal_cell_adhesion1.40515929
39MP0001730_embryonic_growth_arrest1.39056851
40MP0000003_abnormal_adipose_tissue1.37723635
41MP0001348_abnormal_lacrimal_gland1.37341735
42MP0002084_abnormal_developmental_patter1.36972712
43MP0002060_abnormal_skin_morphology1.36822041
44MP0002796_impaired_skin_barrier1.35741437
45MP0005501_abnormal_skin_physiology1.34916491
46MP0000678_abnormal_parathyroid_gland1.34264439
47MP0001293_anophthalmia1.31135127
48MP0001697_abnormal_embryo_size1.30392074
49MP0000703_abnormal_thymus_morphology1.30277066
50MP0003091_abnormal_cell_migration1.30037327
51MP0005621_abnormal_cell_physiology1.29757018
52MP0002086_abnormal_extraembryonic_tissu1.27842842
53MP0002085_abnormal_embryonic_tissue1.27328071
54MP0000733_abnormal_muscle_development1.26835007
55MP0009053_abnormal_anal_canal1.26793263
56MP0001545_abnormal_hematopoietic_system1.24565582
57MP0005397_hematopoietic_system_phenotyp1.24565582
58MP0003890_abnormal_embryonic-extraembry1.24055761
59MP0008932_abnormal_embryonic_tissue1.22926656
60MP0008260_abnormal_autophagy1.22187816
61MP0009703_decreased_birth_body1.21558970
62MP0003705_abnormal_hypodermis_morpholog1.19487574
63MP0003935_abnormal_craniofacial_develop1.17522394
64MP0003385_abnormal_body_wall1.17302043
65MP0002398_abnormal_bone_marrow1.17236245
66MP0000490_abnormal_crypts_of1.17222853
67MP0003122_maternal_imprinting1.16806450
68MP0003787_abnormal_imprinting1.15763009
69MP0003763_abnormal_thymus_physiology1.15354702
70MP0000428_abnormal_craniofacial_morphol1.14931411
71MP0002089_abnormal_postnatal_growth/wei1.14546107
72MP0001661_extended_life_span1.14136243
73MP0003567_abnormal_fetal_cardiomyocyte1.14126378
74MP0002938_white_spotting1.14102751
75MP0003453_abnormal_keratinocyte_physiol1.11060857
76MP0005257_abnormal_intraocular_pressure1.10696104
77MP0002080_prenatal_lethality1.09103474
78MP0002877_abnormal_melanocyte_morpholog1.08243924
79MP0005503_abnormal_tendon_morphology1.08103103
80MP0001915_intracranial_hemorrhage1.07301315
81MP0003279_aneurysm1.06542855
82MP0005384_cellular_phenotype1.05121225
83MP0003300_gastrointestinal_ulcer1.05083738
84MP0010630_abnormal_cardiac_muscle1.05004333
85MP0002925_abnormal_cardiovascular_devel1.04518304
86MP0000432_abnormal_head_morphology1.04496808
87MP0003941_abnormal_skin_development1.02139672
88MP0006292_abnormal_olfactory_placode1.01488050
89MP0005375_adipose_tissue_phenotype1.00900500
90MP0000579_abnormal_nail_morphology0.99774687
91MP0001346_abnormal_lacrimal_gland0.99655905
92MP0000858_altered_metastatic_potential0.99445028
93MP0003221_abnormal_cardiomyocyte_apopto0.98553227
94MP0000566_synostosis0.97726134
95MP0002722_abnormal_immune_system0.97596891
96MP0009672_abnormal_birth_weight0.97532711
97MP0000313_abnormal_cell_death0.97021203
98MP0002249_abnormal_larynx_morphology0.95996427
99MP0001216_abnormal_epidermal_layer0.95636641
100MP0002019_abnormal_tumor_incidence0.93718545
101MP0005058_abnormal_lysosome_morphology0.93348213
102MP0005023_abnormal_wound_healing0.92826708
103MP0003115_abnormal_respiratory_system0.91320388
104MP0003786_premature_aging0.90966242
105MP0005666_abnormal_adipose_tissue0.90398780
106MP0000689_abnormal_spleen_morphology0.89161356
107MP0008438_abnormal_cutaneous_collagen0.88726012
108MP0002166_altered_tumor_susceptibility0.88198084
109MP0000049_abnormal_middle_ear0.87683584
110MP0004264_abnormal_extraembryonic_tissu0.87004584
111MP0002932_abnormal_joint_morphology0.85905274
112MP0002697_abnormal_eye_size0.85730643
113MP0000534_abnormal_ureter_morphology0.84387729
114MP0001286_abnormal_eye_development0.84281451
115MP0000759_abnormal_skeletal_muscle0.83692809
116MP0003755_abnormal_palate_morphology0.83626392
117MP0002092_abnormal_eye_morphology0.83295178
118MP0003937_abnormal_limbs/digits/tail_de0.82772399
119MP0004782_abnormal_surfactant_physiolog0.82379671
120MP0001800_abnormal_humoral_immune0.82288578
121MP0000467_abnormal_esophagus_morphology0.81965967
122MP0002116_abnormal_craniofacial_bone0.81744623
123MP0002006_tumorigenesis0.81558921
124MP0000537_abnormal_urethra_morphology0.81027574
125MP0009333_abnormal_splenocyte_physiolog0.80785449
126MP0003950_abnormal_plasma_membrane0.80660324
127MP0003942_abnormal_urinary_system0.80460970
128MP0000747_muscle_weakness0.80411361
129MP0002114_abnormal_axial_skeleton0.80097392
130MP0000627_abnormal_mammary_gland0.79751518
131MP0005174_abnormal_tail_pigmentation0.79532142
132MP0000716_abnormal_immune_system0.79040600
133MP0003828_pulmonary_edema0.78889555
134MP0004087_abnormal_muscle_fiber0.78260447
135MP0000767_abnormal_smooth_muscle0.78236095
136MP0002098_abnormal_vibrissa_morphology0.78231437
137MP0004233_abnormal_muscle_weight0.77644523
138MP0002429_abnormal_blood_cell0.77464630
139MP0003943_abnormal_hepatobiliary_system0.77450971
140MP0005508_abnormal_skeleton_morphology0.77291735
141MP0000377_abnormal_hair_follicle0.75586086
142MP0000358_abnormal_cell_content/0.75488063
143MP0000762_abnormal_tongue_morphology0.74909202
144MP0001299_abnormal_eye_distance/0.74499057
145MP0003861_abnormal_nervous_system0.73361917
146MP0003656_abnormal_erythrocyte_physiolo0.73123442
147MP0005275_abnormal_skin_tensile0.72833867

Predicted human phenotypes

RankGene SetZ-score
1Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)3.92642037
2Short 4th metacarpal (HP:0010044)3.92642037
3Abnormality of the fingertips (HP:0001211)3.39718222
4Volvulus (HP:0002580)3.33821674
5Premature rupture of membranes (HP:0001788)3.07881937
6Chromsome breakage (HP:0040012)3.06108665
7Long eyelashes (HP:0000527)2.95228734
8Sparse lateral eyebrow (HP:0005338)2.84510688
9Insomnia (HP:0100785)2.69941651
10Chromosomal breakage induced by crosslinking agents (HP:0003221)2.66028135
11Abnormality of the 4th metacarpal (HP:0010012)2.65438087
12Termporal pattern (HP:0011008)2.64610325
13Insidious onset (HP:0003587)2.64610325
14Ectopic kidney (HP:0000086)2.60928275
15Hyperacusis (HP:0010780)2.60241022
16Syringomyelia (HP:0003396)2.60224696
17Spinal cord lesions (HP:0100561)2.60224696
18Trigonocephaly (HP:0000243)2.52285315
19Increased nuchal translucency (HP:0010880)2.47685969
20Supernumerary ribs (HP:0005815)2.42086498
21Dislocated radial head (HP:0003083)2.42044963
22Broad palm (HP:0001169)2.41837427
23Abnormal gallbladder physiology (HP:0012438)2.35622880
24Cholecystitis (HP:0001082)2.35622880
25Disproportionate tall stature (HP:0001519)2.30440769
26Trismus (HP:0000211)2.29771564
27Abnormality of the radial head (HP:0003995)2.27669935
28Deviation of the thumb (HP:0009603)2.26448291
29Long palpebral fissure (HP:0000637)2.26392588
30Shallow orbits (HP:0000586)2.26190804
31Supernumerary bones of the axial skeleton (HP:0009144)2.26085186
32Deep philtrum (HP:0002002)2.24207959
33Dysmetric saccades (HP:0000641)2.23611111
34Urethral obstruction (HP:0000796)2.22302954
35Proximal placement of thumb (HP:0009623)2.18355951
36Ulnar bowing (HP:0003031)2.17512229
37Flat acetabular roof (HP:0003180)2.17256528
38Renal duplication (HP:0000075)2.16019532
39Medulloblastoma (HP:0002885)2.15902386
40Obstructive sleep apnea (HP:0002870)2.15348953
41Advanced eruption of teeth (HP:0006288)2.13935560
42Cortical dysplasia (HP:0002539)2.12493305
43Ankyloglossia (HP:0010296)2.11346690
44Broad thumb (HP:0011304)2.09187057
45Vertebral compression fractures (HP:0002953)2.08162919
46Distal lower limb amyotrophy (HP:0008944)2.06771127
47Absent frontal sinuses (HP:0002688)2.05676437
48Selective tooth agenesis (HP:0001592)2.04559893
49Ependymoma (HP:0002888)2.04528191
50Upper limb amyotrophy (HP:0009129)2.03017307
51Distal upper limb amyotrophy (HP:0007149)2.03017307
52Abnormal number of incisors (HP:0011064)2.02911528
53Patellar dislocation (HP:0002999)1.99868882
54Broad face (HP:0000283)1.99107862
55Unilateral renal agenesis (HP:0000122)1.99036549
56Overriding aorta (HP:0002623)1.98429401
57Progressive muscle weakness (HP:0003323)1.97096194
58Abnormality of the metopic suture (HP:0005556)1.96752216
59Increased density of long bones (HP:0006392)1.96244926
60Hammertoe (HP:0001765)1.94829106
61Abnormality of the parietal bone (HP:0002696)1.94229199
62Natal tooth (HP:0000695)1.92777173
63Acute myeloid leukemia (HP:0004808)1.91836517
64Centrally nucleated skeletal muscle fibers (HP:0003687)1.91428077
65Persistence of primary teeth (HP:0006335)1.90835622
66Abnormality of the nasal septum (HP:0000419)1.90665874
67Acute lymphatic leukemia (HP:0006721)1.88430886
68Narrow palate (HP:0000189)1.87366082
69Heterotopia (HP:0002282)1.86718434
70Bladder diverticulum (HP:0000015)1.85052534
71Broad phalanges of the hand (HP:0009768)1.84935335
72Vertebral arch anomaly (HP:0008438)1.84760680
73Truncal obesity (HP:0001956)1.84023049
74Colon cancer (HP:0003003)1.82854488
75Hand muscle atrophy (HP:0009130)1.82692917
76Prominent nose (HP:0000448)1.82352110
77Mesomelia (HP:0003027)1.82344288
78Abnormality of the calcaneus (HP:0008364)1.80705470
79Abnormality of oral frenula (HP:0000190)1.80403786
80Elfin facies (HP:0004428)1.80094792
81Cervical subluxation (HP:0003308)1.80089580
82Relative macrocephaly (HP:0004482)1.80065569
83Pointed chin (HP:0000307)1.79754750
84Hypoplastic labia majora (HP:0000059)1.79737421
85Hypoplasia of the maxilla (HP:0000327)1.79587829
86Preauricular skin tag (HP:0000384)1.78572212
87Septate vagina (HP:0001153)1.77742631
88Achilles tendon contracture (HP:0001771)1.77369352
89Meckel diverticulum (HP:0002245)1.77194374
90Long clavicles (HP:0000890)1.76568729
91Protrusio acetabuli (HP:0003179)1.76001331
92Limited elbow extension (HP:0001377)1.75293951
93Abnormality of the astrocytes (HP:0100707)1.75104507
94Astrocytoma (HP:0009592)1.75104507
95Abnormality of the phalanges of the hallux (HP:0010057)1.75059342
96Low anterior hairline (HP:0000294)1.74231720
97Myelodysplasia (HP:0002863)1.73610997
98Short nail (HP:0001799)1.73430010
99Reticulocytosis (HP:0001923)1.73169560
100Osteolytic defects of the phalanges of the hand (HP:0009771)1.72955847
101Osteolytic defects of the hand bones (HP:0009699)1.72955847
102Abnormality of chromosome stability (HP:0003220)1.72483721
103Spinal rigidity (HP:0003306)1.72251450
104Abnormality of the distal phalanges of the toes (HP:0010182)1.71176056
105Skin tags (HP:0010609)1.70981203
106Overlapping toe (HP:0001845)1.70799217
107Abnormality of the distal phalanx of the thumb (HP:0009617)1.69947911
108Smooth philtrum (HP:0000319)1.69302648
109Short philtrum (HP:0000322)1.68996840
110Abnormality of the labia majora (HP:0012881)1.68988089
111Back pain (HP:0003418)1.68903671
112High pitched voice (HP:0001620)1.68735517
113Malignant gastrointestinal tract tumors (HP:0006749)1.68667555
114Gastrointestinal carcinoma (HP:0002672)1.68667555
115Increased connective tissue (HP:0009025)1.68458074
116Abnormality of the ileum (HP:0001549)1.68390429
117Entropion (HP:0000621)1.68242768
118Cutis marmorata (HP:0000965)1.68198010
119Neoplasm of the oral cavity (HP:0100649)1.68109254
120Skull defect (HP:0001362)1.67012778
121Synophrys (HP:0000664)1.66934516
122Lower limb amyotrophy (HP:0007210)1.66910057
123Spina bifida occulta (HP:0003298)1.65840301
124Cerebral aneurysm (HP:0004944)1.65773094
125Broad finger (HP:0001500)1.65714821
126Glioma (HP:0009733)1.65396002
127Abnormality of the carotid arteries (HP:0005344)1.64827781
128Bicuspid aortic valve (HP:0001647)1.64818909
129Asymmetry of the thorax (HP:0001555)1.64175603
130Abnormality of the thoracic spine (HP:0100711)1.63957748
131Biconcave vertebral bodies (HP:0004586)1.63806465
132Aplasia/Hypoplasia of the sternum (HP:0006714)1.63227605
133Upper limb muscle weakness (HP:0003484)1.63029481
134Abnormality of the umbilical cord (HP:0010881)1.62386016
135Broad phalanx (HP:0006009)1.62316449
136Slender long bone (HP:0003100)1.62133890
137Abnormality of dentin (HP:0010299)1.62023399
138Progressive hearing impairment (HP:0001730)1.61936504
139Thick eyebrow (HP:0000574)1.61851607
140Optic nerve coloboma (HP:0000588)1.61048418
141Abnormality of the salivary glands (HP:0010286)1.60952297
142Orthostatic hypotension (HP:0001278)1.60819905
143Pseudobulbar signs (HP:0002200)1.60618777
144Arnold-Chiari malformation (HP:0002308)1.60558088
145Aplasia/Hypoplasia of the uvula (HP:0010293)1.60312804
146Broad toe (HP:0001837)1.60161769
147Patellar aplasia (HP:0006443)1.59441685
148Rib fusion (HP:0000902)1.59302927
14911 pairs of ribs (HP:0000878)1.59121467
150Aortic aneurysm (HP:0004942)1.59015700
151Cone-shaped epiphyses of the phalanges of the hand (HP:0010230)1.58963666
152Hereditary nonpolyposis colorectal carcinoma (HP:0006716)1.58147290
153Macroorchidism (HP:0000053)1.58091773
154Progressive external ophthalmoplegia (HP:0000590)1.57878221
155High anterior hairline (HP:0009890)1.57482135
156Abnormality of pain sensation (HP:0010832)1.56830891
157Impaired pain sensation (HP:0007328)1.56830891
158Squamous cell carcinoma (HP:0002860)1.56786721
159Obsessive-compulsive behavior (HP:0000722)1.56053428
160Ureteral obstruction (HP:0006000)1.55512183
161Increased number of teeth (HP:0011069)1.55304173
162Spondylolisthesis (HP:0003302)1.55240640
163Flat cornea (HP:0007720)1.55154966
164Wormian bones (HP:0002645)1.55140403
165Agnosia (HP:0010524)1.55011522
166Elbow flexion contracture (HP:0002987)1.54614289
167Reticulocytopenia (HP:0001896)1.54356721
168Broad long bones (HP:0005622)1.53808047
169Atresia of the external auditory canal (HP:0000413)1.53718186
170Short middle phalanx of the 5th finger (HP:0004220)1.53445568
171Missing ribs (HP:0000921)1.53133827
172Abnormality of the intervertebral disk (HP:0005108)1.52654915
173Anal stenosis (HP:0002025)1.52395701
174Precocious puberty (HP:0000826)1.52158232
175Premature skin wrinkling (HP:0100678)1.52153803
176Renovascular hypertension (HP:0100817)1.51567104

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CDK125.14461158
2SMG13.69454532
3CDC73.29044612
4BRD43.24444719
5EEF2K2.56044323
6NEK22.06489587
7EIF2AK12.00093213
8PASK1.95940734
9PRPF4B1.92093562
10ATR1.85185793
11CAMK1D1.83338625
12FGFR41.78415379
13MKNK11.71851092
14MAP3K101.70533225
15CAMK1G1.69261199
16IRAK31.65510136
17FLT31.63359965
18RPS6KA41.61696631
19CDK71.60871277
20STK101.58244627
21TRIB31.56402335
22MAP4K11.56374563
23MKNK21.47819082
24NME21.47510964
25BRSK21.47279862
26PKN21.46382624
27MTOR1.40743912
28LATS11.40001020
29PRKD31.39315283
30JAK31.38433260
31CDK61.35773045
32CDK41.33143738
33TGFBR11.32995842
34LATS21.31000732
35SRPK11.27716064
36CHUK1.27640313
37CHEK11.27077769
38RPS6KB21.25362097
39TTK1.21886732
40TSSK61.20989430
41STK31.19047109
42TTN1.18273779
43STK41.15695450
44MST1R1.12507376
45NTRK11.12207790
46ATM1.10939946
47PAK41.09055047
48PTK21.07239312
49AURKB1.06229431
50WEE11.04715034
51CDK91.01978858
52PLK41.01936245
53CHEK21.00986517
54PLK31.00276367
55CLK10.98901727
56KIT0.98134158
57PIM10.97585410
58BUB10.97226710
59SIK30.96614916
60PLK10.94828301
61PTK60.92871465
62BTK0.91595830
63EPHA30.91147213
64EPHA20.90565340
65DMPK0.90114529
66PDGFRA0.89334624
67PRKD20.89030227
68SIK10.88107285
69CDK20.88097978
70KSR20.86885502
71ZAK0.86293316
72VRK20.85516676
73ALK0.84875007
74FGFR30.84300206
75SIK20.83153385
76MAP3K80.82827394
77TXK0.80385488
78MET0.78806134
79TESK10.78572926
80PAK20.77501377
81NUAK10.75892886
82SCYL20.74382402
83FGFR10.74358008
84ZAP700.73399270
85MAPK110.72761653
86PBK0.69496252
87MARK30.68292852
88ICK0.68032160
89CSF1R0.66352734
90NEK10.65048471
91* CDK10.64473864
92MARK20.64153061
93MELK0.63526052
94ERBB30.63055428
95TAF10.60863960
96TEC0.60771233
97LRRK20.60425952
98MAPK140.59958938
99WNK10.59802294
100DDR20.59778026
101VRK10.59604615
102TAOK30.59500085
103AKT10.55033817
104AKT20.54746678
105TAOK20.53770691
106* MAPK10.53591266
107MAPK100.53382627
108AURKA0.52785091
109NLK0.52606150
110NEK90.52371527
111ERN10.51600641
112BRSK10.51192174
113TYK20.50760491
114IKBKB0.49400556
115RPS6KL10.49096353
116RPS6KC10.49096353
117PDGFRB0.49089963
118RIPK10.48516205
119HIPK20.48349759
120PRKDC0.48184815
121RPS6KA60.47960907
122EPHB10.47915462
123ITK0.47314867
124AKT30.46510722
125YES10.45030956
126CDC42BPA0.44729986
127HCK0.44441295
128CDK80.44209980
129MAPKAPK20.44191000
130STK240.43611051
131STK380.43484563
132SGK30.43083771
133PIM20.41771589
134GSK3B0.41432677
135RPS6KA20.40640537
136ERBB40.39107254
137CDK11A0.38840987
138CDK150.36511465
139RET0.36429128
140BMX0.36269374
141CSNK1A1L0.35058958
142MAP3K90.35020798
143CSNK1E0.34457639
144CDK180.34431895

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030302.77618347
2Mismatch repair_Homo sapiens_hsa034302.44656952
3Cell cycle_Homo sapiens_hsa041102.28983326
4Base excision repair_Homo sapiens_hsa034102.13045407
5Spliceosome_Homo sapiens_hsa030402.12767431
6Homologous recombination_Homo sapiens_hsa034402.07231037
7Fanconi anemia pathway_Homo sapiens_hsa034602.02838964
8RNA transport_Homo sapiens_hsa030131.98100568
9Non-homologous end-joining_Homo sapiens_hsa034501.94561033
10Biosynthesis of amino acids_Homo sapiens_hsa012301.89784441
11Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.87501917
12Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.87338947
13Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.80436879
14One carbon pool by folate_Homo sapiens_hsa006701.79708885
15mRNA surveillance pathway_Homo sapiens_hsa030151.71101742
16Nucleotide excision repair_Homo sapiens_hsa034201.68501843
172-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.55063717
18Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.53768895
19MicroRNAs in cancer_Homo sapiens_hsa052061.51792619
20RNA degradation_Homo sapiens_hsa030181.50808663
21Chronic myeloid leukemia_Homo sapiens_hsa052201.50602835
22Herpes simplex infection_Homo sapiens_hsa051681.48797976
23Antigen processing and presentation_Homo sapiens_hsa046121.46424867
24p53 signaling pathway_Homo sapiens_hsa041151.44371237
25Pentose phosphate pathway_Homo sapiens_hsa000301.39290503
26Small cell lung cancer_Homo sapiens_hsa052221.38554856
27Notch signaling pathway_Homo sapiens_hsa043301.38289077
28HTLV-I infection_Homo sapiens_hsa051661.36787041
29Adherens junction_Homo sapiens_hsa045201.36430417
30Transcriptional misregulation in cancer_Homo sapiens_hsa052021.34376932
31Lysine degradation_Homo sapiens_hsa003101.33027668
32NF-kappa B signaling pathway_Homo sapiens_hsa040641.31377865
33Measles_Homo sapiens_hsa051621.28032126
34Primary immunodeficiency_Homo sapiens_hsa053401.27683638
35Carbon metabolism_Homo sapiens_hsa012001.22767141
36Basal cell carcinoma_Homo sapiens_hsa052171.19030651
37Viral carcinogenesis_Homo sapiens_hsa052031.18915580
38Acute myeloid leukemia_Homo sapiens_hsa052211.13930027
39Epstein-Barr virus infection_Homo sapiens_hsa051691.13774410
40Longevity regulating pathway - multiple species_Homo sapiens_hsa042131.13552613
41Viral myocarditis_Homo sapiens_hsa054161.13274283
42Renal cell carcinoma_Homo sapiens_hsa052111.11414994
43Colorectal cancer_Homo sapiens_hsa052101.09506462
44Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.08718769
45Hepatitis B_Homo sapiens_hsa051611.08446369
46B cell receptor signaling pathway_Homo sapiens_hsa046621.08314539
47Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.08268364
48Thyroid cancer_Homo sapiens_hsa052161.05687396
49Leishmaniasis_Homo sapiens_hsa051401.03628838
50Prostate cancer_Homo sapiens_hsa052151.03413471
51Fructose and mannose metabolism_Homo sapiens_hsa000511.03224788
52Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.02714759
53ErbB signaling pathway_Homo sapiens_hsa040121.01792082
54TGF-beta signaling pathway_Homo sapiens_hsa043501.00857264
55Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.98652507
56Pancreatic cancer_Homo sapiens_hsa052120.98617619
57Insulin signaling pathway_Homo sapiens_hsa049100.98116167
58Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.97888685
59Basal transcription factors_Homo sapiens_hsa030220.95097872
60Proteoglycans in cancer_Homo sapiens_hsa052050.94889522
61Prion diseases_Homo sapiens_hsa050200.92270491
62Apoptosis_Homo sapiens_hsa042100.91532829
63Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.91519690
64Hematopoietic cell lineage_Homo sapiens_hsa046400.91164313
65Osteoclast differentiation_Homo sapiens_hsa043800.90272143
66Thyroid hormone signaling pathway_Homo sapiens_hsa049190.89706405
67Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.89311341
68AMPK signaling pathway_Homo sapiens_hsa041520.89300635
69Influenza A_Homo sapiens_hsa051640.88506220
70Toxoplasmosis_Homo sapiens_hsa051450.88399082
71Hippo signaling pathway_Homo sapiens_hsa043900.87906057
72Endometrial cancer_Homo sapiens_hsa052130.87438564
73Pathways in cancer_Homo sapiens_hsa052000.87092023
74VEGF signaling pathway_Homo sapiens_hsa043700.86260415
75Jak-STAT signaling pathway_Homo sapiens_hsa046300.85731115
76Focal adhesion_Homo sapiens_hsa045100.85551067
77T cell receptor signaling pathway_Homo sapiens_hsa046600.83987633
78Neurotrophin signaling pathway_Homo sapiens_hsa047220.83577970
79N-Glycan biosynthesis_Homo sapiens_hsa005100.83380829
80Other glycan degradation_Homo sapiens_hsa005110.83268335
81Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.82273737
82RNA polymerase_Homo sapiens_hsa030200.82185233
83Hedgehog signaling pathway_Homo sapiens_hsa043400.82149409
84Non-small cell lung cancer_Homo sapiens_hsa052230.82037569
85mTOR signaling pathway_Homo sapiens_hsa041500.81914286
86Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.81548427
87AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.81530057
88Estrogen signaling pathway_Homo sapiens_hsa049150.80172204
89Leukocyte transendothelial migration_Homo sapiens_hsa046700.79668348
90Inositol phosphate metabolism_Homo sapiens_hsa005620.79491590
91Vibrio cholerae infection_Homo sapiens_hsa051100.79467468
92NOD-like receptor signaling pathway_Homo sapiens_hsa046210.78449667
93Wnt signaling pathway_Homo sapiens_hsa043100.77852693
94Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.76016382
95Shigellosis_Homo sapiens_hsa051310.75186337
96TNF signaling pathway_Homo sapiens_hsa046680.74257734
97ECM-receptor interaction_Homo sapiens_hsa045120.73478012
98Toll-like receptor signaling pathway_Homo sapiens_hsa046200.73158983
99Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.72123205
100Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.69773227
101Melanoma_Homo sapiens_hsa052180.69586694
102Pyrimidine metabolism_Homo sapiens_hsa002400.69564787
103Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.67419998
104Regulation of actin cytoskeleton_Homo sapiens_hsa048100.67120745
105Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.67028143
106FoxO signaling pathway_Homo sapiens_hsa040680.66574519
107Intestinal immune network for IgA production_Homo sapiens_hsa046720.65578400
108Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.65194553
109Glycosaminoglycan degradation_Homo sapiens_hsa005310.65178841
110Bladder cancer_Homo sapiens_hsa052190.64429108
111HIF-1 signaling pathway_Homo sapiens_hsa040660.64392027
112PI3K-Akt signaling pathway_Homo sapiens_hsa041510.63842104
113Central carbon metabolism in cancer_Homo sapiens_hsa052300.63580098
114Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.63151340
115Galactose metabolism_Homo sapiens_hsa000520.62532921
116Legionellosis_Homo sapiens_hsa051340.62243057
117Platelet activation_Homo sapiens_hsa046110.62081289
118Choline metabolism in cancer_Homo sapiens_hsa052310.60907498
119Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.59799712
120Cysteine and methionine metabolism_Homo sapiens_hsa002700.58797532
121Phosphatidylinositol signaling system_Homo sapiens_hsa040700.58126447
122Glucagon signaling pathway_Homo sapiens_hsa049220.57610993
123Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.57428428
124Oocyte meiosis_Homo sapiens_hsa041140.56638619
125Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.55675626
126Glioma_Homo sapiens_hsa052140.55279603
127Hepatitis C_Homo sapiens_hsa051600.54881597
128Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.54861438
129RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.54055534
130Vitamin B6 metabolism_Homo sapiens_hsa007500.53657556
131Ribosome_Homo sapiens_hsa030100.52516100
132Cyanoamino acid metabolism_Homo sapiens_hsa004600.52439640
133Selenocompound metabolism_Homo sapiens_hsa004500.50918022
134Fatty acid biosynthesis_Homo sapiens_hsa000610.50605499
135Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.50514504
136Longevity regulating pathway - mammal_Homo sapiens_hsa042110.48764493
137Prolactin signaling pathway_Homo sapiens_hsa049170.48578390
138Insulin resistance_Homo sapiens_hsa049310.48525050
139Endocytosis_Homo sapiens_hsa041440.47701589
140Gap junction_Homo sapiens_hsa045400.47379339
141Amoebiasis_Homo sapiens_hsa051460.46915486
142Tight junction_Homo sapiens_hsa045300.46759992

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »