

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | GDP-mannose metabolic process (GO:0019673) | 9.70429041 |
| 2 | mannose metabolic process (GO:0006013) | 9.04262623 |
| 3 | chaperone-mediated protein transport (GO:0072321) | 8.86386758 |
| 4 | DNA deamination (GO:0045006) | 7.67151994 |
| 5 | nucleoside transmembrane transport (GO:1901642) | 7.32930872 |
| 6 | nucleoside transport (GO:0015858) | 6.04967438 |
| 7 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 5.56875437 |
| 8 | ATP synthesis coupled proton transport (GO:0015986) | 5.56875437 |
| 9 | interferon-gamma production (GO:0032609) | 5.38841845 |
| 10 | cytidine metabolic process (GO:0046087) | 5.32159025 |
| 11 | cytidine catabolic process (GO:0006216) | 5.32159025 |
| 12 | cytidine deamination (GO:0009972) | 5.32159025 |
| 13 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 4.78053540 |
| 14 | behavioral response to nicotine (GO:0035095) | 4.72913871 |
| 15 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 4.52991891 |
| 16 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 4.33628397 |
| 17 | positive regulation of defense response to virus by host (GO:0002230) | 4.32183622 |
| 18 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 4.31383170 |
| 19 | regulation of immunoglobulin secretion (GO:0051023) | 4.23699269 |
| 20 | outer ear morphogenesis (GO:0042473) | 4.01163719 |
| 21 | endoderm formation (GO:0001706) | 3.90145755 |
| 22 | cofactor transport (GO:0051181) | 3.81082084 |
| 23 | response to pheromone (GO:0019236) | 3.80916675 |
| 24 | modified amino acid transport (GO:0072337) | 3.80082759 |
| 25 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.74679944 |
| 26 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.74679944 |
| 27 | viral transcription (GO:0019083) | 3.63801741 |
| 28 | reproduction (GO:0000003) | 3.61853649 |
| 29 | translational elongation (GO:0006414) | 3.53083371 |
| 30 | nucleotide-sugar biosynthetic process (GO:0009226) | 3.52379858 |
| 31 | translational termination (GO:0006415) | 3.49141655 |
| 32 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 3.48969565 |
| 33 | sulfur compound transport (GO:0072348) | 3.47392554 |
| 34 | ribosomal small subunit assembly (GO:0000028) | 3.46185686 |
| 35 | negative regulation of cAMP-mediated signaling (GO:0043951) | 3.45992220 |
| 36 | positive regulation of fatty acid transport (GO:2000193) | 3.44083882 |
| 37 | ribosomal small subunit biogenesis (GO:0042274) | 3.38911927 |
| 38 | peroxisome fission (GO:0016559) | 3.34350329 |
| 39 | chaperone mediated protein folding requiring cofactor (GO:0051085) | 3.32369077 |
| 40 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 3.24370072 |
| 41 | ATP biosynthetic process (GO:0006754) | 3.23567691 |
| 42 | positive regulation of icosanoid secretion (GO:0032305) | 3.22505335 |
| 43 | cotranslational protein targeting to membrane (GO:0006613) | 3.22430808 |
| 44 | amine catabolic process (GO:0009310) | 3.16040885 |
| 45 | cellular biogenic amine catabolic process (GO:0042402) | 3.16040885 |
| 46 | positive regulation of fatty acid oxidation (GO:0046321) | 3.15761074 |
| 47 | protein targeting to ER (GO:0045047) | 3.15642322 |
| 48 | positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523) | 3.15530403 |
| 49 | regulation of mitochondrial membrane potential (GO:0051881) | 3.12905886 |
| 50 | regulation of isotype switching to IgG isotypes (GO:0048302) | 3.09734429 |
| 51 | cellular response to interleukin-15 (GO:0071350) | 3.08858337 |
| 52 | intracellular protein transmembrane import (GO:0044743) | 3.07499209 |
| 53 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 3.07162556 |
| 54 | viral protein processing (GO:0019082) | 3.05201296 |
| 55 | somatic diversification of immunoglobulins involved in immune response (GO:0002208) | 3.03803708 |
| 56 | isotype switching (GO:0045190) | 3.03803708 |
| 57 | somatic recombination of immunoglobulin genes involved in immune response (GO:0002204) | 3.03803708 |
| 58 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 3.03265073 |
| 59 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 3.02894911 |
| 60 | cellular response to estradiol stimulus (GO:0071392) | 3.02317035 |
| 61 | protein localization to endoplasmic reticulum (GO:0070972) | 3.00628795 |
| 62 | pantothenate metabolic process (GO:0015939) | 2.99789412 |
| 63 | electron transport chain (GO:0022900) | 2.98444985 |
| 64 | translation (GO:0006412) | 2.98113403 |
| 65 | respiratory electron transport chain (GO:0022904) | 2.96443295 |
| 66 | coenzyme A biosynthetic process (GO:0015937) | 2.96233164 |
| 67 | monocyte chemotaxis (GO:0002548) | 2.95653175 |
| 68 | hydrogen ion transmembrane transport (GO:1902600) | 2.95489183 |
| 69 | carbohydrate derivative transport (GO:1901264) | 2.94788239 |
| 70 | positive regulation of insulin secretion involved in cellular response to glucose stimulus (GO:00357 | 2.94326432 |
| 71 | histone H2A acetylation (GO:0043968) | 2.86574082 |
| 72 | proton transport (GO:0015992) | 2.84752072 |
| 73 | hydrogen transport (GO:0006818) | 2.78116459 |
| 74 | regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522) | 2.76797139 |
| 75 | regulation of chronic inflammatory response (GO:0002676) | 2.75012816 |
| 76 | short-chain fatty acid metabolic process (GO:0046459) | 2.72743242 |
| 77 | dolichol-linked oligosaccharide biosynthetic process (GO:0006488) | 2.72353825 |
| 78 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 2.70149736 |
| 79 | deoxyribonucleoside triphosphate metabolic process (GO:0009200) | 2.66984864 |
| 80 | cobalamin metabolic process (GO:0009235) | 2.64422600 |
| 81 | indolalkylamine metabolic process (GO:0006586) | 2.63094306 |
| 82 | positive regulation of fatty acid beta-oxidation (GO:0032000) | 2.62932563 |
| 83 | viral life cycle (GO:0019058) | 2.61851347 |
| 84 | negative regulation of B cell apoptotic process (GO:0002903) | 2.60866996 |
| 85 | cellular protein complex disassembly (GO:0043624) | 2.60643425 |
| 86 | water-soluble vitamin biosynthetic process (GO:0042364) | 2.58379131 |
| 87 | purine deoxyribonucleoside triphosphate metabolic process (GO:0009215) | 2.55502130 |
| 88 | GTP biosynthetic process (GO:0006183) | 2.55212961 |
| 89 | indole-containing compound catabolic process (GO:0042436) | 2.51927595 |
| 90 | indolalkylamine catabolic process (GO:0046218) | 2.51927595 |
| 91 | tryptophan catabolic process (GO:0006569) | 2.51927595 |
| 92 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 2.51426794 |
| 93 | urinary tract smooth muscle contraction (GO:0014848) | 2.50676582 |
| 94 | negative regulation by host of viral transcription (GO:0043922) | 2.50503937 |
| 95 | ribonucleoside triphosphate biosynthetic process (GO:0009201) | 2.50076937 |
| 96 | regulation of defense response to virus by host (GO:0050691) | 2.49320371 |
| 97 | positive regulation of myoblast differentiation (GO:0045663) | 2.47937167 |
| 98 | regulation of receptor binding (GO:1900120) | 2.47667583 |
| 99 | otic vesicle formation (GO:0030916) | 2.46031933 |
| 100 | establishment of protein localization to peroxisome (GO:0072663) | 2.45342956 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 7.13392184 |
| 2 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 5.04084992 |
| 3 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 3.94394754 |
| 4 | EZH2_22144423_ChIP-Seq_EOC_Human | 3.04719837 |
| 5 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 2.85665949 |
| 6 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 2.30616228 |
| 7 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.24345901 |
| 8 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.19435570 |
| 9 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.14621637 |
| 10 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 2.12794272 |
| 11 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 2.11519729 |
| 12 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.10235039 |
| 13 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 2.08355093 |
| 14 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.08150672 |
| 15 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 2.05360393 |
| 16 | VDR_22108803_ChIP-Seq_LS180_Human | 2.05279753 |
| 17 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 2.02099721 |
| 18 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 1.90158151 |
| 19 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 1.67185184 |
| 20 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 1.66505357 |
| 21 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.66487672 |
| 22 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.65831664 |
| 23 | GATA6_21074721_ChIP-Seq_CACO-2_Mouse | 1.58213429 |
| 24 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 1.55756035 |
| 25 | RUNX_20019798_ChIP-Seq_JUKART_Human | 1.54411386 |
| 26 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.51029560 |
| 27 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.49802161 |
| 28 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.45136250 |
| 29 | HTT_18923047_ChIP-ChIP_STHdh_Human | 1.41009655 |
| 30 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.40690754 |
| 31 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.39950334 |
| 32 | EBNA1_20929547_Chip-Seq_RAJI-cells_Human | 1.33790930 |
| 33 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.33332313 |
| 34 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.32382294 |
| 35 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 1.31357029 |
| 36 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.28121625 |
| 37 | GATA6_21074721_ChIP-Seq_CACO-2_Human | 1.28085508 |
| 38 | PHF8_20622853_ChIP-Seq_HELA_Human | 1.26344757 |
| 39 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.25266398 |
| 40 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.24298504 |
| 41 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.24005189 |
| 42 | GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.22960361 |
| 43 | ETV1_20927104_ChIP-Seq_GIST48_Human | 1.21477297 |
| 44 | BMI1_19503595_ChIP-Seq_MEFsC_Mouse | 1.21422167 |
| 45 | MYC_19829295_ChIP-Seq_ESCs_Human | 1.19764973 |
| 46 | RBPJ_21746931_ChIP-Seq_IB4_Human | 1.19483327 |
| 47 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.19148383 |
| 48 | CDX2_21074721_ChIP-Seq_CACO-2_Mouse | 1.19070568 |
| 49 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.17834303 |
| 50 | EWS_26573619_Chip-Seq_HEK293_Human | 1.17675799 |
| 51 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.16339071 |
| 52 | TAF2_19829295_ChIP-Seq_ESCs_Human | 1.15981767 |
| 53 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.15231368 |
| 54 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.15084386 |
| 55 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 1.13602172 |
| 56 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.12490083 |
| 57 | NCOR_22424771_ChIP-Seq_293T_Human | 1.12062202 |
| 58 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.11671497 |
| 59 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.11660212 |
| 60 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 1.10855846 |
| 61 | GATA3_26560356_Chip-Seq_TH2_Human | 1.08889200 |
| 62 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.08368553 |
| 63 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 1.07531433 |
| 64 | NFYB_21822215_ChIP-Seq_K562_Human | 1.07431843 |
| 65 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 1.06482472 |
| 66 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 1.06353530 |
| 67 | NFYA_21822215_ChIP-Seq_K562_Human | 1.05936787 |
| 68 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 1.05517427 |
| 69 | PCGF4_22325352_ChIP-Seq_293T-Rex_Human | 1.04634690 |
| 70 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.03725389 |
| 71 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.03725389 |
| 72 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.03454205 |
| 73 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 1.02725623 |
| 74 | HOXB7_26014856_ChIP-Seq_BT474_Human | 1.02294823 |
| 75 | P53_21459846_ChIP-Seq_SAOS-2_Human | 1.02098814 |
| 76 | HNFA_21074721_ChIP-Seq_CACO-2_Human | 1.01875482 |
| 77 | FOXP3_21729870_ChIP-Seq_TREG_Human | 0.98461281 |
| 78 | CBX2_22325352_ChIP-Seq_293T-Rex_Human | 0.98039028 |
| 79 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 0.97947259 |
| 80 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 0.97537011 |
| 81 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 0.96833565 |
| 82 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 0.96825912 |
| 83 | RNF2_27304074_Chip-Seq_NSC_Mouse | 0.96655202 |
| 84 | ERA_21632823_ChIP-Seq_H3396_Human | 0.96317877 |
| 85 | E2F1_20622854_ChIP-Seq_HELA_Human | 0.96301462 |
| 86 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 0.95943357 |
| 87 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 0.95174382 |
| 88 | BCAT_22108803_ChIP-Seq_LS180_Human | 0.94985491 |
| 89 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 0.93294805 |
| 90 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 0.93261089 |
| 91 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 0.93261024 |
| 92 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 0.93098845 |
| 93 | ERG_20517297_ChIP-Seq_VCAP_Human | 0.92355896 |
| 94 | TBL1_22424771_ChIP-Seq_293T_Human | 0.90746731 |
| 95 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 0.90674891 |
| 96 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 0.90492060 |
| 97 | YY1_22570637_ChIP-Seq_MALME-3M_Human | 0.90049545 |
| 98 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 0.89167981 |
| 99 | BCL6_27268052_Chip-Seq_Bcells_Human | 0.88879432 |
| 100 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 0.88876863 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0002638_abnormal_pupillary_reflex | 5.64678870 |
| 2 | MP0005671_abnormal_response_to | 4.03357414 |
| 3 | MP0005360_urolithiasis | 3.86121980 |
| 4 | MP0006072_abnormal_retinal_apoptosis | 3.44451298 |
| 5 | MP0003646_muscle_fatigue | 3.35189698 |
| 6 | MP0004043_abnormal_pH_regulation | 3.20967091 |
| 7 | MP0009379_abnormal_foot_pigmentation | 3.05935164 |
| 8 | MP0004145_abnormal_muscle_electrophysio | 2.38698724 |
| 9 | MP0001873_stomach_inflammation | 2.34973469 |
| 10 | MP0005387_immune_system_phenotype | 2.27453237 |
| 11 | MP0001790_abnormal_immune_system | 2.27453237 |
| 12 | MP0002837_dystrophic_cardiac_calcinosis | 2.14555990 |
| 13 | MP0003011_delayed_dark_adaptation | 2.14060017 |
| 14 | MP0001835_abnormal_antigen_presentation | 2.07794706 |
| 15 | MP0008875_abnormal_xenobiotic_pharmacok | 2.05357020 |
| 16 | MP0002102_abnormal_ear_morphology | 1.97246198 |
| 17 | MP0008872_abnormal_physiological_respon | 1.81492191 |
| 18 | MP0000685_abnormal_immune_system | 1.74551679 |
| 19 | MP0001968_abnormal_touch/_nociception | 1.67885353 |
| 20 | MP0006292_abnormal_olfactory_placode | 1.65985831 |
| 21 | MP0005645_abnormal_hypothalamus_physiol | 1.65436088 |
| 22 | MP0003195_calcinosis | 1.62820592 |
| 23 | MP0001485_abnormal_pinna_reflex | 1.61758439 |
| 24 | MP0006082_CNS_inflammation | 1.59842450 |
| 25 | MP0000372_irregular_coat_pigmentation | 1.51454096 |
| 26 | MP0008260_abnormal_autophagy | 1.50721863 |
| 27 | MP0001905_abnormal_dopamine_level | 1.47070127 |
| 28 | MP0001727_abnormal_embryo_implantation | 1.46901868 |
| 29 | MP0009333_abnormal_splenocyte_physiolog | 1.45759662 |
| 30 | MP0001986_abnormal_taste_sensitivity | 1.45160759 |
| 31 | MP0000604_amyloidosis | 1.43592924 |
| 32 | MP0004142_abnormal_muscle_tone | 1.43151642 |
| 33 | MP0008877_abnormal_DNA_methylation | 1.40806384 |
| 34 | MP0002148_abnormal_hypersensitivity_rea | 1.40763007 |
| 35 | MP0005253_abnormal_eye_physiology | 1.35875998 |
| 36 | MP0002138_abnormal_hepatobiliary_system | 1.32659626 |
| 37 | MP0002163_abnormal_gland_morphology | 1.32526528 |
| 38 | MP0001853_heart_inflammation | 1.31886887 |
| 39 | MP0003283_abnormal_digestive_organ | 1.30777382 |
| 40 | MP0005551_abnormal_eye_electrophysiolog | 1.23981714 |
| 41 | MP0002653_abnormal_ependyma_morphology | 1.20226393 |
| 42 | MP0005379_endocrine/exocrine_gland_phen | 1.18608391 |
| 43 | MP0004885_abnormal_endolymph | 1.17462361 |
| 44 | MP0001529_abnormal_vocalization | 1.17342967 |
| 45 | MP0003329_amyloid_beta_deposits | 1.16878441 |
| 46 | MP0009785_altered_susceptibility_to | 1.12679863 |
| 47 | MP0005389_reproductive_system_phenotype | 1.11749450 |
| 48 | MP0002733_abnormal_thermal_nociception | 1.11304126 |
| 49 | MP0005377_hearing/vestibular/ear_phenot | 1.10283316 |
| 50 | MP0003878_abnormal_ear_physiology | 1.10283316 |
| 51 | MP0002160_abnormal_reproductive_system | 1.07196419 |
| 52 | MP0006276_abnormal_autonomic_nervous | 1.07086909 |
| 53 | MP0001800_abnormal_humoral_immune | 1.06410988 |
| 54 | MP0005000_abnormal_immune_tolerance | 1.06024170 |
| 55 | MP0002272_abnormal_nervous_system | 1.05421970 |
| 56 | MP0005084_abnormal_gallbladder_morpholo | 1.05336488 |
| 57 | MP0004742_abnormal_vestibular_system | 1.04131661 |
| 58 | MP0002095_abnormal_skin_pigmentation | 1.00508331 |
| 59 | MP0009745_abnormal_behavioral_response | 0.99085390 |
| 60 | MP0004133_heterotaxia | 0.98008136 |
| 61 | MP0003567_abnormal_fetal_cardiomyocyte | 0.97631811 |
| 62 | MP0002736_abnormal_nociception_after | 0.97609965 |
| 63 | MP0001542_abnormal_bone_strength | 0.97236065 |
| 64 | MP0002723_abnormal_immune_serum | 0.96390445 |
| 65 | MP0000049_abnormal_middle_ear | 0.95252959 |
| 66 | MP0009764_decreased_sensitivity_to | 0.93280095 |
| 67 | MP0005025_abnormal_response_to | 0.92537476 |
| 68 | MP0005195_abnormal_posterior_eye | 0.90742907 |
| 69 | MP0001970_abnormal_pain_threshold | 0.87176729 |
| 70 | MP0010386_abnormal_urinary_bladder | 0.86829787 |
| 71 | MP0005083_abnormal_biliary_tract | 0.83931672 |
| 72 | MP0005174_abnormal_tail_pigmentation | 0.80993557 |
| 73 | MP0008775_abnormal_heart_ventricle | 0.80966556 |
| 74 | MP0000778_abnormal_nervous_system | 0.78936019 |
| 75 | MP0002557_abnormal_social/conspecific_i | 0.75953558 |
| 76 | MP0002572_abnormal_emotion/affect_behav | 0.75130729 |
| 77 | MP0002277_abnormal_respiratory_mucosa | 0.72228855 |
| 78 | MP0002420_abnormal_adaptive_immunity | 0.71601044 |
| 79 | MP0002933_joint_inflammation | 0.71521069 |
| 80 | MP0010155_abnormal_intestine_physiology | 0.71479316 |
| 81 | MP0002735_abnormal_chemical_nociception | 0.71101708 |
| 82 | MP0005464_abnormal_platelet_physiology | 0.70707830 |
| 83 | MP0003122_maternal_imprinting | 0.70361939 |
| 84 | MP0005220_abnormal_exocrine_pancreas | 0.69321498 |
| 85 | MP0008007_abnormal_cellular_replicative | 0.68594222 |
| 86 | MP0005448_abnormal_energy_balance | 0.67863151 |
| 87 | MP0009250_abnormal_appendicular_skeleto | 0.67490087 |
| 88 | MP0001819_abnormal_immune_cell | 0.67054694 |
| 89 | MP0003787_abnormal_imprinting | 0.65472205 |
| 90 | MP0002210_abnormal_sex_determination | 0.65338308 |
| 91 | MP0000538_abnormal_urinary_bladder | 0.65303689 |
| 92 | MP0001845_abnormal_inflammatory_respons | 0.63713280 |
| 93 | MP0002234_abnormal_pharynx_morphology | 0.63593485 |
| 94 | MP0002693_abnormal_pancreas_physiology | 0.63222197 |
| 95 | MP0005085_abnormal_gallbladder_physiolo | 0.63025894 |
| 96 | MP0001919_abnormal_reproductive_system | 0.62609853 |
| 97 | MP0006036_abnormal_mitochondrial_physio | 0.62085381 |
| 98 | MP0000689_abnormal_spleen_morphology | 0.62039825 |
| 99 | MP0002752_abnormal_somatic_nervous | 0.61659661 |
| 100 | MP0005332_abnormal_amino_acid | 0.60536169 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Global brain atrophy (HP:0002283) | 5.84557218 |
| 2 | Hypobetalipoproteinemia (HP:0003563) | 4.76061682 |
| 3 | Methylmalonic acidemia (HP:0002912) | 4.32696650 |
| 4 | Congenital stationary night blindness (HP:0007642) | 4.18673078 |
| 5 | Akinesia (HP:0002304) | 4.11892926 |
| 6 | Methylmalonic aciduria (HP:0012120) | 3.88094516 |
| 7 | Stomatitis (HP:0010280) | 3.85815917 |
| 8 | Elevated erythrocyte sedimentation rate (HP:0003565) | 3.79760222 |
| 9 | Neurodegeneration (HP:0002180) | 3.74645453 |
| 10 | Acanthocytosis (HP:0001927) | 3.53835876 |
| 11 | Abnormality of midbrain morphology (HP:0002418) | 3.40579543 |
| 12 | Molar tooth sign on MRI (HP:0002419) | 3.40579543 |
| 13 | Hyperglycinemia (HP:0002154) | 3.39794615 |
| 14 | Increased CSF lactate (HP:0002490) | 3.36936154 |
| 15 | Abnormality of the phalanges of the 2nd finger (HP:0009541) | 3.27441849 |
| 16 | Patent foramen ovale (HP:0001655) | 3.21910508 |
| 17 | Hepatocellular necrosis (HP:0001404) | 3.14637114 |
| 18 | Hepatic necrosis (HP:0002605) | 3.14000779 |
| 19 | Mitochondrial inheritance (HP:0001427) | 3.09917045 |
| 20 | IgG deficiency (HP:0004315) | 3.09185254 |
| 21 | Dysphonia (HP:0001618) | 3.08797350 |
| 22 | Tongue fasciculations (HP:0001308) | 3.08195557 |
| 23 | Microretrognathia (HP:0000308) | 3.08172750 |
| 24 | Delayed CNS myelination (HP:0002188) | 3.07678380 |
| 25 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 3.06351318 |
| 26 | Abnormality of alanine metabolism (HP:0010916) | 3.06351318 |
| 27 | Hyperalaninemia (HP:0003348) | 3.06351318 |
| 28 | Diminished movement (HP:0002374) | 2.99279209 |
| 29 | Decreased muscle mass (HP:0003199) | 2.96835534 |
| 30 | Agitation (HP:0000713) | 2.92276836 |
| 31 | Dyskinesia (HP:0100660) | 2.88310494 |
| 32 | Hypoplasia of the pons (HP:0012110) | 2.72944461 |
| 33 | Increased IgM level (HP:0003496) | 2.71330283 |
| 34 | Muscle fibrillation (HP:0010546) | 2.61342449 |
| 35 | Abnormality of vitamin B metabolism (HP:0004340) | 2.61037300 |
| 36 | Increased hepatocellular lipid droplets (HP:0006565) | 2.56170934 |
| 37 | Acute necrotizing encephalopathy (HP:0006965) | 2.54166743 |
| 38 | Parakeratosis (HP:0001036) | 2.52466106 |
| 39 | Agammaglobulinemia (HP:0004432) | 2.51935534 |
| 40 | Congenital, generalized hypertrichosis (HP:0004540) | 2.48386400 |
| 41 | CNS demyelination (HP:0007305) | 2.47903779 |
| 42 | Abnormality of the vitamin B12 metabolism (HP:0004341) | 2.47284596 |
| 43 | Craniofacial dystonia (HP:0012179) | 2.44207789 |
| 44 | Partial duplication of the phalanx of hand (HP:0009999) | 2.39807524 |
| 45 | Morphological abnormality of the pyramidal tract (HP:0002062) | 2.38827879 |
| 46 | Abnormality of the pons (HP:0007361) | 2.38633355 |
| 47 | Tubulointerstitial nephritis (HP:0001970) | 2.30672114 |
| 48 | Focal dystonia (HP:0004373) | 2.30587971 |
| 49 | Ketoacidosis (HP:0001993) | 2.27127242 |
| 50 | Stenosis of the external auditory canal (HP:0000402) | 2.27004040 |
| 51 | Abnormality of the basal ganglia (HP:0002134) | 2.26933436 |
| 52 | Lipid accumulation in hepatocytes (HP:0006561) | 2.24979167 |
| 53 | Nephronophthisis (HP:0000090) | 2.24490441 |
| 54 | Hypolipoproteinemia (HP:0010981) | 2.22184463 |
| 55 | T lymphocytopenia (HP:0005403) | 2.21130120 |
| 56 | Increased serum lactate (HP:0002151) | 2.19473173 |
| 57 | Medial flaring of the eyebrow (HP:0010747) | 2.18970911 |
| 58 | Pancreatic cysts (HP:0001737) | 2.18714483 |
| 59 | Severe muscular hypotonia (HP:0006829) | 2.18503449 |
| 60 | Hemiplegia (HP:0002301) | 2.17944711 |
| 61 | Clumsiness (HP:0002312) | 2.11216630 |
| 62 | Brushfield spots (HP:0001088) | 2.10297086 |
| 63 | Large eyes (HP:0001090) | 2.09607433 |
| 64 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.09386562 |
| 65 | Ketosis (HP:0001946) | 2.08912117 |
| 66 | Abnormal mitochondria in muscle tissue (HP:0008316) | 2.06817095 |
| 67 | Abnormality of T cells (HP:0002843) | 2.04700778 |
| 68 | Abnormality of long-chain fatty-acid metabolism (HP:0010964) | 2.01228545 |
| 69 | True hermaphroditism (HP:0010459) | 1.98770147 |
| 70 | Renal cortical cysts (HP:0000803) | 1.98625618 |
| 71 | Progressive macrocephaly (HP:0004481) | 1.97766558 |
| 72 | Renal Fanconi syndrome (HP:0001994) | 1.97490335 |
| 73 | Abnormal rod and cone electroretinograms (HP:0008323) | 1.96168333 |
| 74 | Type 2 muscle fiber atrophy (HP:0003554) | 1.96140154 |
| 75 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 1.96117853 |
| 76 | Abnormality of T cell number (HP:0011839) | 1.93916927 |
| 77 | Abnormality of serum amino acid levels (HP:0003112) | 1.92236252 |
| 78 | Hypoalbuminemia (HP:0003073) | 1.91793907 |
| 79 | Abnormal albumin level (HP:0012116) | 1.91793907 |
| 80 | Pendular nystagmus (HP:0012043) | 1.91193538 |
| 81 | Recurrent bronchitis (HP:0002837) | 1.90918545 |
| 82 | Restlessness (HP:0000711) | 1.89579777 |
| 83 | Keratoconus (HP:0000563) | 1.86337643 |
| 84 | Increased corneal curvature (HP:0100692) | 1.86337643 |
| 85 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 1.85978254 |
| 86 | Dicarboxylic aciduria (HP:0003215) | 1.85978254 |
| 87 | Abnormality of the phalanges of the hallux (HP:0010057) | 1.85195269 |
| 88 | Generalized aminoaciduria (HP:0002909) | 1.82957089 |
| 89 | Renal tubular dysfunction (HP:0000124) | 1.82349472 |
| 90 | Broad distal phalanx of finger (HP:0009836) | 1.82044574 |
| 91 | Acute encephalopathy (HP:0006846) | 1.81848820 |
| 92 | Hypoproteinemia (HP:0003075) | 1.80575326 |
| 93 | Glycosuria (HP:0003076) | 1.79336467 |
| 94 | Abnormality of urine glucose concentration (HP:0011016) | 1.79336467 |
| 95 | Severe combined immunodeficiency (HP:0004430) | 1.75911234 |
| 96 | Respiratory difficulties (HP:0002880) | 1.75863246 |
| 97 | Amblyopia (HP:0000646) | 1.73218520 |
| 98 | Hypomagnesemia (HP:0002917) | 1.72297102 |
| 99 | Poor suck (HP:0002033) | 1.70258363 |
| 100 | Abnormality of the 2nd finger (HP:0004100) | 1.69740231 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TESK2 | 5.03699798 |
| 2 | PDK2 | 4.81118204 |
| 3 | GRK1 | 3.56819988 |
| 4 | BCKDK | 3.15196048 |
| 5 | ADRBK2 | 3.07386233 |
| 6 | TXK | 3.03155732 |
| 7 | ERN1 | 2.37164819 |
| 8 | ZAK | 1.98047149 |
| 9 | MST4 | 1.97176128 |
| 10 | TLK1 | 1.95743653 |
| 11 | MAP2K6 | 1.84083361 |
| 12 | PHKG2 | 1.69675213 |
| 13 | PHKG1 | 1.69675213 |
| 14 | MAP4K2 | 1.68367108 |
| 15 | LIMK1 | 1.67167856 |
| 16 | BMPR1B | 1.62658697 |
| 17 | WNK3 | 1.53281123 |
| 18 | TAOK3 | 1.45896165 |
| 19 | CDK8 | 1.38328791 |
| 20 | TGFBR1 | 1.37104412 |
| 21 | FRK | 1.30543981 |
| 22 | OBSCN | 1.29908351 |
| 23 | MAP3K12 | 1.24683175 |
| 24 | PASK | 1.22935970 |
| 25 | DYRK2 | 1.22109413 |
| 26 | WNK4 | 1.16605117 |
| 27 | DAPK2 | 1.16602529 |
| 28 | KDR | 1.13956648 |
| 29 | NME1 | 1.12228490 |
| 30 | TESK1 | 1.12135945 |
| 31 | INSRR | 1.09557380 |
| 32 | ITK | 1.07730130 |
| 33 | LCK | 1.05560469 |
| 34 | GRK7 | 1.05403225 |
| 35 | VRK1 | 1.04774159 |
| 36 | FES | 1.02982342 |
| 37 | VRK2 | 1.01087958 |
| 38 | EPHB2 | 1.00720076 |
| 39 | SYK | 1.00212167 |
| 40 | MAPKAPK3 | 0.97281277 |
| 41 | MAP2K7 | 0.97036003 |
| 42 | BUB1 | 0.93567551 |
| 43 | ADRBK1 | 0.91823143 |
| 44 | DAPK1 | 0.91002163 |
| 45 | PINK1 | 0.89214117 |
| 46 | PKN1 | 0.88248855 |
| 47 | TBK1 | 0.87086316 |
| 48 | PRKCQ | 0.84499012 |
| 49 | AKT2 | 0.81080325 |
| 50 | MAPK13 | 0.79923580 |
| 51 | PRKCG | 0.79497157 |
| 52 | TIE1 | 0.73290793 |
| 53 | TEC | 0.72216906 |
| 54 | PRKCI | 0.70541277 |
| 55 | ABL2 | 0.67641661 |
| 56 | DYRK1B | 0.66063229 |
| 57 | PRKACA | 0.65181480 |
| 58 | IKBKB | 0.63438548 |
| 59 | STK38 | 0.62955784 |
| 60 | MAPK7 | 0.60133507 |
| 61 | MAP2K2 | 0.59832620 |
| 62 | PRKCE | 0.59775591 |
| 63 | PRKD2 | 0.59508437 |
| 64 | CAMK2A | 0.58953380 |
| 65 | AURKA | 0.57884652 |
| 66 | CCNB1 | 0.57307991 |
| 67 | IKBKE | 0.56417558 |
| 68 | PRKCH | 0.54631430 |
| 69 | PIK3CA | 0.54332991 |
| 70 | MUSK | 0.53338393 |
| 71 | PRKCA | 0.51530922 |
| 72 | NUAK1 | 0.51440423 |
| 73 | CSNK2A1 | 0.49161263 |
| 74 | DAPK3 | 0.48580232 |
| 75 | PAK3 | 0.44824710 |
| 76 | MINK1 | 0.44577182 |
| 77 | ROCK1 | 0.41786768 |
| 78 | MAP3K11 | 0.41662583 |
| 79 | PIK3CG | 0.40298359 |
| 80 | NTRK2 | 0.40170519 |
| 81 | MAP3K4 | 0.39682427 |
| 82 | PIM2 | 0.39421098 |
| 83 | TRIM28 | 0.38919643 |
| 84 | STK38L | 0.38668598 |
| 85 | PLK2 | 0.36842276 |
| 86 | GRK5 | 0.36732806 |
| 87 | RPS6KA5 | 0.36552923 |
| 88 | CSK | 0.36514313 |
| 89 | CAMK2G | 0.36334417 |
| 90 | CSNK2A2 | 0.36136576 |
| 91 | PRKCD | 0.34933471 |
| 92 | BTK | 0.33675543 |
| 93 | EIF2AK3 | 0.31301370 |
| 94 | ATR | 0.30913130 |
| 95 | INSR | 0.30470361 |
| 96 | PRKD3 | 0.29520053 |
| 97 | PIM1 | 0.29516496 |
| 98 | RPS6KA1 | 0.29225207 |
| 99 | NME2 | 0.29055640 |
| 100 | PRKG1 | 0.28095574 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Ribosome_Homo sapiens_hsa03010 | 4.19306487 |
| 2 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.43533678 |
| 3 | Primary immunodeficiency_Homo sapiens_hsa05340 | 3.09568864 |
| 4 | Allograft rejection_Homo sapiens_hsa05330 | 2.98178707 |
| 5 | Parkinsons disease_Homo sapiens_hsa05012 | 2.97393977 |
| 6 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.95306438 |
| 7 | Asthma_Homo sapiens_hsa05310 | 2.92184255 |
| 8 | Proteasome_Homo sapiens_hsa03050 | 2.87302098 |
| 9 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 2.35199909 |
| 10 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 2.19824388 |
| 11 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 2.17364470 |
| 12 | Alzheimers disease_Homo sapiens_hsa05010 | 2.09904981 |
| 13 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 2.06951660 |
| 14 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.93687373 |
| 15 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.89190606 |
| 16 | Regulation of autophagy_Homo sapiens_hsa04140 | 1.85639905 |
| 17 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.80049931 |
| 18 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.79463664 |
| 19 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 1.74131927 |
| 20 | Huntingtons disease_Homo sapiens_hsa05016 | 1.71432898 |
| 21 | Protein export_Homo sapiens_hsa03060 | 1.71217298 |
| 22 | RNA degradation_Homo sapiens_hsa03018 | 1.67509314 |
| 23 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.65511726 |
| 24 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.55548054 |
| 25 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 1.50661932 |
| 26 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 1.47183058 |
| 27 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.45842291 |
| 28 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.41597913 |
| 29 | Phototransduction_Homo sapiens_hsa04744 | 1.39991751 |
| 30 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.38788841 |
| 31 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.33889581 |
| 32 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 1.29785135 |
| 33 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 1.29140651 |
| 34 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.26754251 |
| 35 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.21673934 |
| 36 | Peroxisome_Homo sapiens_hsa04146 | 1.20668113 |
| 37 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.17942998 |
| 38 | RNA polymerase_Homo sapiens_hsa03020 | 1.16917098 |
| 39 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.12859828 |
| 40 | Folate biosynthesis_Homo sapiens_hsa00790 | 1.11616099 |
| 41 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.09155473 |
| 42 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 1.05191549 |
| 43 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.03510485 |
| 44 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.98811569 |
| 45 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.94247266 |
| 46 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.93107148 |
| 47 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.87810186 |
| 48 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.81877409 |
| 49 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.80918899 |
| 50 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.79639260 |
| 51 | Taste transduction_Homo sapiens_hsa04742 | 0.79137399 |
| 52 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.78891653 |
| 53 | Viral myocarditis_Homo sapiens_hsa05416 | 0.72747226 |
| 54 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.72358759 |
| 55 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.70909912 |
| 56 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.67135842 |
| 57 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.65739526 |
| 58 | Olfactory transduction_Homo sapiens_hsa04740 | 0.65605833 |
| 59 | Insulin secretion_Homo sapiens_hsa04911 | 0.64267497 |
| 60 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.64056196 |
| 61 | Homologous recombination_Homo sapiens_hsa03440 | 0.62640513 |
| 62 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.60420206 |
| 63 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.59958651 |
| 64 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.58855951 |
| 65 | Basal transcription factors_Homo sapiens_hsa03022 | 0.55739884 |
| 66 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.55694195 |
| 67 | Retinol metabolism_Homo sapiens_hsa00830 | 0.55406364 |
| 68 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.53893717 |
| 69 | Metabolic pathways_Homo sapiens_hsa01100 | 0.53159202 |
| 70 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.51637884 |
| 71 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.51439515 |
| 72 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.51335821 |
| 73 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.50586567 |
| 74 | Purine metabolism_Homo sapiens_hsa00230 | 0.50060757 |
| 75 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.47517563 |
| 76 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.46583792 |
| 77 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.45611992 |
| 78 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.43796571 |
| 79 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.43656109 |
| 80 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.43629502 |
| 81 | Salivary secretion_Homo sapiens_hsa04970 | 0.41742960 |
| 82 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.39857071 |
| 83 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.36444261 |
| 84 | Nicotine addiction_Homo sapiens_hsa05033 | 0.35427786 |
| 85 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.31986056 |
| 86 | GABAergic synapse_Homo sapiens_hsa04727 | 0.31032990 |
| 87 | Malaria_Homo sapiens_hsa05144 | 0.30077322 |
| 88 | Morphine addiction_Homo sapiens_hsa05032 | 0.30036832 |
| 89 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.28067638 |
| 90 | PPAR signaling pathway_Homo sapiens_hsa03320 | 0.26581881 |
| 91 | Mineral absorption_Homo sapiens_hsa04978 | 0.26342921 |
| 92 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.26234267 |
| 93 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.25321296 |
| 94 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.22098957 |
| 95 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 0.19009727 |
| 96 | Mismatch repair_Homo sapiens_hsa03430 | 0.18282427 |
| 97 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.17821094 |
| 98 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.16253372 |
| 99 | Measles_Homo sapiens_hsa05162 | 0.14598687 |
| 100 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.13321820 |

