

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | DNA deamination (GO:0045006) | 4.87926933 |
| 2 | L-serine transport (GO:0015825) | 4.79011552 |
| 3 | behavioral response to nicotine (GO:0035095) | 4.68509450 |
| 4 | somite rostral/caudal axis specification (GO:0032525) | 4.02498436 |
| 5 | serine transport (GO:0032329) | 3.98399376 |
| 6 | ATP synthesis coupled proton transport (GO:0015986) | 3.91759027 |
| 7 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 3.91759027 |
| 8 | ribosomal small subunit assembly (GO:0000028) | 3.82107705 |
| 9 | indolalkylamine metabolic process (GO:0006586) | 3.73286879 |
| 10 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.72335064 |
| 11 | kidney morphogenesis (GO:0060993) | 3.71513897 |
| 12 | regulation of mesoderm development (GO:2000380) | 3.69860352 |
| 13 | negative regulation of activin receptor signaling pathway (GO:0032926) | 3.68057819 |
| 14 | platelet dense granule organization (GO:0060155) | 3.64205275 |
| 15 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 3.64119530 |
| 16 | glycerophospholipid catabolic process (GO:0046475) | 3.60665084 |
| 17 | neuron fate determination (GO:0048664) | 3.54269881 |
| 18 | photoreceptor cell maintenance (GO:0045494) | 3.53058841 |
| 19 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 3.52963919 |
| 20 | maturation of SSU-rRNA (GO:0030490) | 3.46223026 |
| 21 | chromatin remodeling at centromere (GO:0031055) | 3.39564859 |
| 22 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.32786155 |
| 23 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.30185996 |
| 24 | termination of RNA polymerase III transcription (GO:0006386) | 3.30185996 |
| 25 | regulation of male gonad development (GO:2000018) | 3.28678384 |
| 26 | rRNA catabolic process (GO:0016075) | 3.26619322 |
| 27 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.26111415 |
| 28 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.19377750 |
| 29 | protein neddylation (GO:0045116) | 3.18493996 |
| 30 | lateral ventricle development (GO:0021670) | 3.17294694 |
| 31 | detection of mechanical stimulus involved in sensory perception of sound (GO:0050910) | 3.15137042 |
| 32 | CENP-A containing nucleosome assembly (GO:0034080) | 3.12891999 |
| 33 | positive regulation of gastrulation (GO:2000543) | 3.11929380 |
| 34 | cellular biogenic amine biosynthetic process (GO:0042401) | 3.05581463 |
| 35 | chaperone-mediated protein transport (GO:0072321) | 3.04460508 |
| 36 | anterograde synaptic vesicle transport (GO:0048490) | 3.03017352 |
| 37 | replication fork processing (GO:0031297) | 3.02500319 |
| 38 | phosphatidylserine metabolic process (GO:0006658) | 3.01420178 |
| 39 | regulation of action potential (GO:0098900) | 3.00164214 |
| 40 | ribosomal small subunit biogenesis (GO:0042274) | 2.99678502 |
| 41 | primitive streak formation (GO:0090009) | 2.96707279 |
| 42 | transmission of nerve impulse (GO:0019226) | 2.95675078 |
| 43 | translational termination (GO:0006415) | 2.95561053 |
| 44 | histone exchange (GO:0043486) | 2.94743727 |
| 45 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 2.93735855 |
| 46 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 2.93735855 |
| 47 | NADH dehydrogenase complex assembly (GO:0010257) | 2.93735855 |
| 48 | viral transcription (GO:0019083) | 2.92254449 |
| 49 | protein complex biogenesis (GO:0070271) | 2.90264900 |
| 50 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 2.89566846 |
| 51 | preassembly of GPI anchor in ER membrane (GO:0016254) | 2.88791245 |
| 52 | endoderm formation (GO:0001706) | 2.88285348 |
| 53 | cotranslational protein targeting to membrane (GO:0006613) | 2.88250691 |
| 54 | protein targeting to ER (GO:0045047) | 2.86420454 |
| 55 | parturition (GO:0007567) | 2.86347982 |
| 56 | DNA methylation involved in gamete generation (GO:0043046) | 2.85234540 |
| 57 | amine biosynthetic process (GO:0009309) | 2.81184845 |
| 58 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 2.77021870 |
| 59 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 2.77021870 |
| 60 | synaptic transmission, cholinergic (GO:0007271) | 2.75568236 |
| 61 | synapsis (GO:0007129) | 2.73059464 |
| 62 | intracellular protein transmembrane import (GO:0044743) | 2.72915986 |
| 63 | RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503) | 2.72754992 |
| 64 | protein localization to endoplasmic reticulum (GO:0070972) | 2.72027909 |
| 65 | signal transduction involved in regulation of gene expression (GO:0023019) | 2.71768103 |
| 66 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 2.70621032 |
| 67 | mitochondrial respiratory chain complex assembly (GO:0033108) | 2.69023989 |
| 68 | respiratory chain complex IV assembly (GO:0008535) | 2.68606794 |
| 69 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 2.66070399 |
| 70 | pyrimidine nucleobase catabolic process (GO:0006208) | 2.65730163 |
| 71 | regulation of cilium movement (GO:0003352) | 2.64422483 |
| 72 | embryonic axis specification (GO:0000578) | 2.63504675 |
| 73 | piRNA metabolic process (GO:0034587) | 2.61340618 |
| 74 | epithelial cilium movement (GO:0003351) | 2.61056007 |
| 75 | glycosphingolipid biosynthetic process (GO:0006688) | 2.60287269 |
| 76 | protein K6-linked ubiquitination (GO:0085020) | 2.60215417 |
| 77 | GTP biosynthetic process (GO:0006183) | 2.58564841 |
| 78 | translation (GO:0006412) | 2.57919587 |
| 79 | termination of RNA polymerase I transcription (GO:0006363) | 2.57631551 |
| 80 | positive regulation of protein autophosphorylation (GO:0031954) | 2.57440539 |
| 81 | ketone body metabolic process (GO:1902224) | 2.57318407 |
| 82 | brain morphogenesis (GO:0048854) | 2.56785931 |
| 83 | cell migration involved in gastrulation (GO:0042074) | 2.56234204 |
| 84 | anterior/posterior axis specification (GO:0009948) | 2.54451589 |
| 85 | anterior/posterior axis specification, embryo (GO:0008595) | 2.52099599 |
| 86 | ncRNA catabolic process (GO:0034661) | 2.51537224 |
| 87 | retinal rod cell development (GO:0046548) | 2.50782438 |
| 88 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 2.48407068 |
| 89 | translational elongation (GO:0006414) | 2.47288402 |
| 90 | sensory perception of smell (GO:0007608) | 2.45511023 |
| 91 | anterograde axon cargo transport (GO:0008089) | 2.44018697 |
| 92 | startle response (GO:0001964) | 2.43655530 |
| 93 | short-chain fatty acid metabolic process (GO:0046459) | 2.42651652 |
| 94 | regulation of acetyl-CoA biosynthetic process from pyruvate (GO:0010510) | 2.42221854 |
| 95 | proton transport (GO:0015992) | 2.41914290 |
| 96 | cellular response to cholesterol (GO:0071397) | 2.41163662 |
| 97 | negative regulation of DNA-dependent DNA replication (GO:2000104) | 2.41024663 |
| 98 | tRNA processing (GO:0008033) | 2.39672713 |
| 99 | negative regulation of intracellular estrogen receptor signaling pathway (GO:0033147) | 2.39631657 |
| 100 | electron transport chain (GO:0022900) | 2.39402267 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | EZH2_22144423_ChIP-Seq_EOC_Human | 4.76718149 |
| 2 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 3.33602940 |
| 3 | VDR_22108803_ChIP-Seq_LS180_Human | 3.25446780 |
| 4 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 3.20078814 |
| 5 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 2.98620595 |
| 6 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.67860276 |
| 7 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.59359554 |
| 8 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 2.54024250 |
| 9 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 2.53755654 |
| 10 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.51950652 |
| 11 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.51434462 |
| 12 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.47634313 |
| 13 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.26128927 |
| 14 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 2.23316674 |
| 15 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 2.14413064 |
| 16 | P300_19829295_ChIP-Seq_ESCs_Human | 2.08794205 |
| 17 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.95742758 |
| 18 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.88029078 |
| 19 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.80140700 |
| 20 | FUS_26573619_Chip-Seq_HEK293_Human | 1.79477810 |
| 21 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.76661873 |
| 22 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 1.75003301 |
| 23 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.73862766 |
| 24 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.71637489 |
| 25 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.69290079 |
| 26 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.66582263 |
| 27 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.61412105 |
| 28 | EWS_26573619_Chip-Seq_HEK293_Human | 1.59401311 |
| 29 | SMAD3_21741376_ChIP-Seq_HESCs_Human | 1.56962980 |
| 30 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 1.55987493 |
| 31 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.54731255 |
| 32 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.54627141 |
| 33 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.50208057 |
| 34 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.49581018 |
| 35 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.47192753 |
| 36 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.42171988 |
| 37 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.40931556 |
| 38 | SMAD4_21741376_ChIP-Seq_EPCs_Human | 1.36785816 |
| 39 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.34235634 |
| 40 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 1.34133790 |
| 41 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.32436282 |
| 42 | SMAD4_21741376_ChIP-Seq_HESCs_Human | 1.32146788 |
| 43 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.30376731 |
| 44 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.28430714 |
| 45 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.27663872 |
| 46 | TCF4_22108803_ChIP-Seq_LS180_Human | 1.26345745 |
| 47 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.24740051 |
| 48 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.24593490 |
| 49 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.24396774 |
| 50 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.22857850 |
| 51 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.19448622 |
| 52 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.18354800 |
| 53 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 1.18014349 |
| 54 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.17982582 |
| 55 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.17860300 |
| 56 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.17070200 |
| 57 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.16886981 |
| 58 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.16679769 |
| 59 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.14670410 |
| 60 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.14263836 |
| 61 | KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse | 1.14160746 |
| 62 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.12851155 |
| 63 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.12195428 |
| 64 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.12195428 |
| 65 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 1.11854026 |
| 66 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.11429519 |
| 67 | REST_21632747_ChIP-Seq_MESCs_Mouse | 1.09966529 |
| 68 | RUNX2_22187159_ChIP-Seq_PCA_Human | 1.07713825 |
| 69 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.07470923 |
| 70 | NCOR_22424771_ChIP-Seq_293T_Human | 1.05466673 |
| 71 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.05451174 |
| 72 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.04201817 |
| 73 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.02030911 |
| 74 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 0.99481329 |
| 75 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 0.99374773 |
| 76 | STAT3_23295773_ChIP-Seq_U87_Human | 0.97945974 |
| 77 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 0.97876239 |
| 78 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 0.97773162 |
| 79 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 0.96641345 |
| 80 | JUN_21703547_ChIP-Seq_K562_Human | 0.95545527 |
| 81 | AR_25329375_ChIP-Seq_VCAP_Human | 0.95543943 |
| 82 | AR_20517297_ChIP-Seq_VCAP_Human | 0.94740446 |
| 83 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 0.94716583 |
| 84 | CDX2_22108803_ChIP-Seq_LS180_Human | 0.94255579 |
| 85 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 0.93698732 |
| 86 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 0.92130842 |
| 87 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 0.91985681 |
| 88 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 0.91525112 |
| 89 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 0.91383797 |
| 90 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 0.91383797 |
| 91 | SMAD3_21741376_ChIP-Seq_ESCs_Human | 0.90811643 |
| 92 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 0.90032206 |
| 93 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 0.89747903 |
| 94 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 0.89556352 |
| 95 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 0.88933301 |
| 96 | RNF2_27304074_Chip-Seq_NSC_Mouse | 0.88470798 |
| 97 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 0.87919563 |
| 98 | ETV1_20927104_ChIP-Seq_GIST48_Human | 0.87006574 |
| 99 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 0.86149022 |
| 100 | TCF4_23295773_ChIP-Seq_U87_Human | 0.85909588 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0005499_abnormal_olfactory_system | 4.45941904 |
| 2 | MP0005394_taste/olfaction_phenotype | 4.45941904 |
| 3 | MP0006292_abnormal_olfactory_placode | 4.20136911 |
| 4 | MP0003890_abnormal_embryonic-extraembry | 3.64489241 |
| 5 | MP0002102_abnormal_ear_morphology | 3.62005260 |
| 6 | MP0003787_abnormal_imprinting | 3.49778135 |
| 7 | MP0009379_abnormal_foot_pigmentation | 3.41066783 |
| 8 | MP0001984_abnormal_olfaction | 3.39587647 |
| 9 | MP0004145_abnormal_muscle_electrophysio | 3.36254567 |
| 10 | MP0008789_abnormal_olfactory_epithelium | 3.27906986 |
| 11 | MP0008877_abnormal_DNA_methylation | 3.13041151 |
| 12 | MP0003136_yellow_coat_color | 2.82316138 |
| 13 | MP0003122_maternal_imprinting | 2.19710576 |
| 14 | MP0003121_genomic_imprinting | 2.08839495 |
| 15 | MP0001968_abnormal_touch/_nociception | 2.01065220 |
| 16 | MP0002234_abnormal_pharynx_morphology | 1.94757765 |
| 17 | MP0008872_abnormal_physiological_respon | 1.88705335 |
| 18 | MP0005084_abnormal_gallbladder_morpholo | 1.80288841 |
| 19 | MP0004133_heterotaxia | 1.77852126 |
| 20 | MP0008058_abnormal_DNA_repair | 1.76231175 |
| 21 | MP0003119_abnormal_digestive_system | 1.75506168 |
| 22 | MP0000372_irregular_coat_pigmentation | 1.75352197 |
| 23 | MP0005174_abnormal_tail_pigmentation | 1.73043924 |
| 24 | MP0002736_abnormal_nociception_after | 1.72877071 |
| 25 | MP0002837_dystrophic_cardiac_calcinosis | 1.67695161 |
| 26 | MP0004885_abnormal_endolymph | 1.66659882 |
| 27 | MP0006276_abnormal_autonomic_nervous | 1.66132684 |
| 28 | MP0002938_white_spotting | 1.64161230 |
| 29 | MP0008875_abnormal_xenobiotic_pharmacok | 1.63354870 |
| 30 | MP0002184_abnormal_innervation | 1.49235369 |
| 31 | MP0001188_hyperpigmentation | 1.48778865 |
| 32 | MP0002138_abnormal_hepatobiliary_system | 1.45021676 |
| 33 | MP0001986_abnormal_taste_sensitivity | 1.44765453 |
| 34 | MP0005551_abnormal_eye_electrophysiolog | 1.42618422 |
| 35 | MP0001529_abnormal_vocalization | 1.41670003 |
| 36 | MP0001293_anophthalmia | 1.37914771 |
| 37 | MP0004147_increased_porphyrin_level | 1.37357208 |
| 38 | MP0001485_abnormal_pinna_reflex | 1.35557861 |
| 39 | MP0005075_abnormal_melanosome_morpholog | 1.34055334 |
| 40 | MP0003718_maternal_effect | 1.32952907 |
| 41 | MP0004742_abnormal_vestibular_system | 1.30136092 |
| 42 | MP0009745_abnormal_behavioral_response | 1.26841454 |
| 43 | MP0005645_abnormal_hypothalamus_physiol | 1.20199081 |
| 44 | MP0006035_abnormal_mitochondrial_morpho | 1.20177407 |
| 45 | MP0002272_abnormal_nervous_system | 1.19431749 |
| 46 | MP0003880_abnormal_central_pattern | 1.18962061 |
| 47 | MP0005377_hearing/vestibular/ear_phenot | 1.16527241 |
| 48 | MP0003878_abnormal_ear_physiology | 1.16527241 |
| 49 | MP0002254_reproductive_system_inflammat | 1.13611900 |
| 50 | MP0010030_abnormal_orbit_morphology | 1.13608474 |
| 51 | MP0008004_abnormal_stomach_pH | 1.12796960 |
| 52 | MP0006036_abnormal_mitochondrial_physio | 1.08876717 |
| 53 | MP0002557_abnormal_social/conspecific_i | 1.05998966 |
| 54 | MP0006072_abnormal_retinal_apoptosis | 1.05886364 |
| 55 | MP0005253_abnormal_eye_physiology | 1.05458775 |
| 56 | MP0001970_abnormal_pain_threshold | 1.01932394 |
| 57 | MP0003646_muscle_fatigue | 1.01040138 |
| 58 | MP0000015_abnormal_ear_pigmentation | 0.99571022 |
| 59 | MP0009046_muscle_twitch | 0.97867308 |
| 60 | MP0002572_abnormal_emotion/affect_behav | 0.93515995 |
| 61 | MP0006054_spinal_hemorrhage | 0.92943603 |
| 62 | MP0002733_abnormal_thermal_nociception | 0.92626698 |
| 63 | MP0004142_abnormal_muscle_tone | 0.92569174 |
| 64 | MP0002067_abnormal_sensory_capabilities | 0.90681883 |
| 65 | MP0003635_abnormal_synaptic_transmissio | 0.89997457 |
| 66 | MP0002928_abnormal_bile_duct | 0.89195749 |
| 67 | MP0002752_abnormal_somatic_nervous | 0.87943516 |
| 68 | MP0001324_abnormal_eye_pigmentation | 0.85421849 |
| 69 | MP0004381_abnormal_hair_follicle | 0.84530214 |
| 70 | MP0005195_abnormal_posterior_eye | 0.84452741 |
| 71 | MP0004924_abnormal_behavior | 0.84321705 |
| 72 | MP0005386_behavior/neurological_phenoty | 0.84321705 |
| 73 | MP0002095_abnormal_skin_pigmentation | 0.84170980 |
| 74 | MP0005409_darkened_coat_color | 0.83709913 |
| 75 | MP0002638_abnormal_pupillary_reflex | 0.81601271 |
| 76 | MP0003137_abnormal_impulse_conducting | 0.80459761 |
| 77 | MP0003252_abnormal_bile_duct | 0.80422053 |
| 78 | MP0002233_abnormal_nose_morphology | 0.79882104 |
| 79 | MP0005187_abnormal_penis_morphology | 0.78819716 |
| 80 | MP0002751_abnormal_autonomic_nervous | 0.78326440 |
| 81 | MP0003315_abnormal_perineum_morphology | 0.76422521 |
| 82 | MP0003186_abnormal_redox_activity | 0.75816650 |
| 83 | MP0001286_abnormal_eye_development | 0.74219101 |
| 84 | MP0005423_abnormal_somatic_nervous | 0.72654091 |
| 85 | MP0005391_vision/eye_phenotype | 0.71472216 |
| 86 | MP0003567_abnormal_fetal_cardiomyocyte | 0.69947526 |
| 87 | MP0005389_reproductive_system_phenotype | 0.68922661 |
| 88 | MP0002063_abnormal_learning/memory/cond | 0.68279508 |
| 89 | MP0000049_abnormal_middle_ear | 0.67806132 |
| 90 | MP0004019_abnormal_vitamin_homeostasis | 0.67496725 |
| 91 | MP0002210_abnormal_sex_determination | 0.67430883 |
| 92 | MP0000653_abnormal_sex_gland | 0.65110010 |
| 93 | MP0001486_abnormal_startle_reflex | 0.64780414 |
| 94 | MP0003879_abnormal_hair_cell | 0.64202636 |
| 95 | MP0001440_abnormal_grooming_behavior | 0.63864717 |
| 96 | MP0008775_abnormal_heart_ventricle | 0.63860086 |
| 97 | MP0002734_abnormal_mechanical_nocicepti | 0.63264810 |
| 98 | MP0001929_abnormal_gametogenesis | 0.63245648 |
| 99 | MP0002160_abnormal_reproductive_system | 0.63135931 |
| 100 | MP0000026_abnormal_inner_ear | 0.63020745 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Asplenia (HP:0001746) | 3.86721608 |
| 2 | Pancreatic fibrosis (HP:0100732) | 3.84261980 |
| 3 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 3.81097029 |
| 4 | Supernumerary spleens (HP:0009799) | 3.78455875 |
| 5 | Abnormality of the labia minora (HP:0012880) | 3.57762764 |
| 6 | Pancreatic cysts (HP:0001737) | 3.44936818 |
| 7 | Septo-optic dysplasia (HP:0100842) | 3.43611024 |
| 8 | Abdominal situs inversus (HP:0003363) | 3.31778230 |
| 9 | Abnormality of abdominal situs (HP:0011620) | 3.31778230 |
| 10 | Reticulocytopenia (HP:0001896) | 3.17241285 |
| 11 | Acute necrotizing encephalopathy (HP:0006965) | 3.11242089 |
| 12 | Nephronophthisis (HP:0000090) | 3.07753847 |
| 13 | Molar tooth sign on MRI (HP:0002419) | 3.05923503 |
| 14 | Abnormality of midbrain morphology (HP:0002418) | 3.05923503 |
| 15 | Hypoplastic pelvis (HP:0008839) | 3.02856952 |
| 16 | Oligodactyly (hands) (HP:0001180) | 2.97036315 |
| 17 | Colon cancer (HP:0003003) | 2.94260794 |
| 18 | Acute encephalopathy (HP:0006846) | 2.92256171 |
| 19 | Methylmalonic acidemia (HP:0002912) | 2.89042249 |
| 20 | Increased hepatocellular lipid droplets (HP:0006565) | 2.84804568 |
| 21 | Bile duct proliferation (HP:0001408) | 2.84572339 |
| 22 | Abnormal biliary tract physiology (HP:0012439) | 2.84572339 |
| 23 | Abnormality of the renal medulla (HP:0100957) | 2.81929133 |
| 24 | Type II lissencephaly (HP:0007260) | 2.80960125 |
| 25 | Abolished electroretinogram (ERG) (HP:0000550) | 2.75839869 |
| 26 | Renal Fanconi syndrome (HP:0001994) | 2.74557400 |
| 27 | Methylmalonic aciduria (HP:0012120) | 2.71226681 |
| 28 | Progressive macrocephaly (HP:0004481) | 2.70467104 |
| 29 | Lipid accumulation in hepatocytes (HP:0006561) | 2.68200588 |
| 30 | Hyperglycinemia (HP:0002154) | 2.65904426 |
| 31 | Abnormality of the renal cortex (HP:0011035) | 2.58936513 |
| 32 | Increased CSF lactate (HP:0002490) | 2.55647535 |
| 33 | Abnormal mitochondria in muscle tissue (HP:0008316) | 2.53234597 |
| 34 | True hermaphroditism (HP:0010459) | 2.53082568 |
| 35 | Mitochondrial inheritance (HP:0001427) | 2.50723197 |
| 36 | Chronic hepatic failure (HP:0100626) | 2.45061493 |
| 37 | Cystic liver disease (HP:0006706) | 2.44962183 |
| 38 | Adrenal hypoplasia (HP:0000835) | 2.44186834 |
| 39 | Abnormality of DNA repair (HP:0003254) | 2.40364772 |
| 40 | Double outlet right ventricle (HP:0001719) | 2.38295915 |
| 41 | Congenital malformation of the right heart (HP:0011723) | 2.38295915 |
| 42 | Optic disc pallor (HP:0000543) | 2.38230134 |
| 43 | Aplasia/Hypoplasia of the optic nerve (HP:0008058) | 2.33794796 |
| 44 | Optic nerve hypoplasia (HP:0000609) | 2.33386108 |
| 45 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.32771712 |
| 46 | Abnormality of alanine metabolism (HP:0010916) | 2.32771712 |
| 47 | Hyperalaninemia (HP:0003348) | 2.32771712 |
| 48 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.27056564 |
| 49 | Anencephaly (HP:0002323) | 2.26417046 |
| 50 | Congenital stationary night blindness (HP:0007642) | 2.24037824 |
| 51 | Medial flaring of the eyebrow (HP:0010747) | 2.22085050 |
| 52 | Occipital encephalocele (HP:0002085) | 2.21139731 |
| 53 | Respiratory difficulties (HP:0002880) | 2.19571764 |
| 54 | Progressive inability to walk (HP:0002505) | 2.18608704 |
| 55 | Neoplasm of the adrenal cortex (HP:0100641) | 2.17955626 |
| 56 | Tubular atrophy (HP:0000092) | 2.17399067 |
| 57 | Entropion (HP:0000621) | 2.15602344 |
| 58 | Congenital hepatic fibrosis (HP:0002612) | 2.13264514 |
| 59 | Inability to walk (HP:0002540) | 2.08153712 |
| 60 | Congenital, generalized hypertrichosis (HP:0004540) | 2.06639426 |
| 61 | Oligodactyly (HP:0012165) | 2.03315486 |
| 62 | Hyperglycinuria (HP:0003108) | 2.02762019 |
| 63 | Agitation (HP:0000713) | 2.01322534 |
| 64 | Chorioretinal atrophy (HP:0000533) | 1.98642545 |
| 65 | Retinal dysplasia (HP:0007973) | 1.97874814 |
| 66 | Abnormal rod and cone electroretinograms (HP:0008323) | 1.97064895 |
| 67 | Cerebral edema (HP:0002181) | 1.95892046 |
| 68 | Aplasia/Hypoplasia of the tongue (HP:0010295) | 1.95767100 |
| 69 | Delayed CNS myelination (HP:0002188) | 1.94885047 |
| 70 | Abnormality of serine family amino acid metabolism (HP:0010894) | 1.94808953 |
| 71 | Abnormality of glycine metabolism (HP:0010895) | 1.94808953 |
| 72 | Anophthalmia (HP:0000528) | 1.94514748 |
| 73 | Genital tract atresia (HP:0001827) | 1.93479228 |
| 74 | Polydipsia (HP:0001959) | 1.89908983 |
| 75 | Abnormal drinking behavior (HP:0030082) | 1.89908983 |
| 76 | Pancreatic islet-cell hyperplasia (HP:0004510) | 1.89387827 |
| 77 | Myokymia (HP:0002411) | 1.89123040 |
| 78 | Status epilepticus (HP:0002133) | 1.88766143 |
| 79 | Sclerocornea (HP:0000647) | 1.88598476 |
| 80 | Pachygyria (HP:0001302) | 1.87030653 |
| 81 | Lissencephaly (HP:0001339) | 1.86618698 |
| 82 | Renal cortical cysts (HP:0000803) | 1.86457512 |
| 83 | Preaxial hand polydactyly (HP:0001177) | 1.84547531 |
| 84 | Pendular nystagmus (HP:0012043) | 1.82915035 |
| 85 | Exertional dyspnea (HP:0002875) | 1.81360533 |
| 86 | Polyuria (HP:0000103) | 1.81222127 |
| 87 | Postaxial foot polydactyly (HP:0001830) | 1.80515344 |
| 88 | Leukodystrophy (HP:0002415) | 1.80203592 |
| 89 | 3-Methylglutaconic aciduria (HP:0003535) | 1.77524059 |
| 90 | Abnormality of renal resorption (HP:0011038) | 1.77045577 |
| 91 | Abnormal lung lobation (HP:0002101) | 1.76982110 |
| 92 | Optic nerve coloboma (HP:0000588) | 1.76942940 |
| 93 | Vaginal atresia (HP:0000148) | 1.76568932 |
| 94 | Lethargy (HP:0001254) | 1.74700306 |
| 95 | Abnormal hair whorl (HP:0010721) | 1.74480251 |
| 96 | Dandy-Walker malformation (HP:0001305) | 1.74163756 |
| 97 | Labial hypoplasia (HP:0000066) | 1.73622442 |
| 98 | Abnormality of urine glucose concentration (HP:0011016) | 1.72208470 |
| 99 | Glycosuria (HP:0003076) | 1.72208470 |
| 100 | Absent septum pellucidum (HP:0001331) | 1.71875361 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | STK16 | 5.42309039 |
| 2 | BMPR1B | 3.39571911 |
| 3 | ACVR1B | 3.39445143 |
| 4 | TIE1 | 3.14161415 |
| 5 | GRK1 | 3.07830445 |
| 6 | ADRBK2 | 2.46217078 |
| 7 | WNK4 | 2.41701328 |
| 8 | NUAK1 | 2.26154284 |
| 9 | TRIM28 | 1.95298632 |
| 10 | EIF2AK1 | 1.95271372 |
| 11 | MKNK2 | 1.86951845 |
| 12 | FRK | 1.79428395 |
| 13 | ERBB4 | 1.77279103 |
| 14 | PINK1 | 1.77096114 |
| 15 | TNIK | 1.76711187 |
| 16 | TGFBR1 | 1.74823242 |
| 17 | CSNK1G1 | 1.71083712 |
| 18 | CSNK1G3 | 1.70387653 |
| 19 | CSNK1G2 | 1.66986088 |
| 20 | PDK2 | 1.62021984 |
| 21 | PLK2 | 1.49441171 |
| 22 | OXSR1 | 1.46418547 |
| 23 | CSNK1A1L | 1.42608048 |
| 24 | WNK3 | 1.39294526 |
| 25 | STK39 | 1.36650893 |
| 26 | EIF2AK3 | 1.29083425 |
| 27 | MAPK13 | 1.29061869 |
| 28 | VRK2 | 1.27557638 |
| 29 | BUB1 | 1.25549292 |
| 30 | PLK3 | 1.17952809 |
| 31 | BCKDK | 1.15813608 |
| 32 | ADRBK1 | 1.08507082 |
| 33 | DYRK2 | 1.06516932 |
| 34 | PRKCG | 1.04843446 |
| 35 | ZAK | 1.04370418 |
| 36 | PLK4 | 1.02775771 |
| 37 | NEK1 | 1.02769346 |
| 38 | VRK1 | 1.01131195 |
| 39 | PHKG1 | 1.00237985 |
| 40 | PHKG2 | 1.00237985 |
| 41 | INSRR | 0.96391973 |
| 42 | MKNK1 | 0.92053307 |
| 43 | NTRK2 | 0.88737913 |
| 44 | PRKD3 | 0.88501652 |
| 45 | TYRO3 | 0.88030410 |
| 46 | PBK | 0.86872596 |
| 47 | WNK1 | 0.81160554 |
| 48 | TGFBR2 | 0.79889348 |
| 49 | CASK | 0.79784172 |
| 50 | DAPK3 | 0.78839267 |
| 51 | PLK1 | 0.77299437 |
| 52 | PAK3 | 0.74353685 |
| 53 | ERBB3 | 0.73207565 |
| 54 | DMPK | 0.72776706 |
| 55 | CAMKK2 | 0.72735707 |
| 56 | PRKCQ | 0.70604618 |
| 57 | TLK1 | 0.68716838 |
| 58 | CDK19 | 0.68596709 |
| 59 | PRKCH | 0.68482169 |
| 60 | MAP3K13 | 0.63739742 |
| 61 | MAP2K7 | 0.63344945 |
| 62 | CHEK2 | 0.62753962 |
| 63 | PRKCE | 0.61266439 |
| 64 | EPHA4 | 0.59681894 |
| 65 | PIK3CA | 0.59290731 |
| 66 | BRSK1 | 0.55013494 |
| 67 | CLK1 | 0.54604643 |
| 68 | CSNK1E | 0.52499235 |
| 69 | CSNK1A1 | 0.51766779 |
| 70 | BRSK2 | 0.51201572 |
| 71 | TEC | 0.48767553 |
| 72 | LRRK2 | 0.48738663 |
| 73 | EIF2AK2 | 0.48530547 |
| 74 | ATR | 0.48529314 |
| 75 | WEE1 | 0.48226377 |
| 76 | MINK1 | 0.48224144 |
| 77 | ATM | 0.45549400 |
| 78 | EPHB2 | 0.45264777 |
| 79 | PRKCD | 0.44462136 |
| 80 | PRKDC | 0.43762775 |
| 81 | MST4 | 0.43264267 |
| 82 | FLT3 | 0.43082264 |
| 83 | MAPKAPK3 | 0.41674929 |
| 84 | NTRK1 | 0.40486032 |
| 85 | DAPK2 | 0.40029645 |
| 86 | MAP4K2 | 0.39020024 |
| 87 | MAP3K4 | 0.38269253 |
| 88 | CSNK1D | 0.37071773 |
| 89 | PRKACA | 0.36742669 |
| 90 | TAF1 | 0.36570324 |
| 91 | SGK1 | 0.35795130 |
| 92 | RPS6KB1 | 0.32933463 |
| 93 | STK10 | 0.32419499 |
| 94 | PRKACB | 0.32235785 |
| 95 | CSNK2A2 | 0.32186551 |
| 96 | AURKA | 0.31867748 |
| 97 | PRKCA | 0.30514275 |
| 98 | CAMK2A | 0.29595266 |
| 99 | FES | 0.29477522 |
| 100 | PIM1 | 0.28467392 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Ribosome_Homo sapiens_hsa03010 | 3.56389298 |
| 2 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.17063318 |
| 3 | Protein export_Homo sapiens_hsa03060 | 3.14625842 |
| 4 | Parkinsons disease_Homo sapiens_hsa05012 | 2.63621313 |
| 5 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 2.49716885 |
| 6 | Butanoate metabolism_Homo sapiens_hsa00650 | 2.47039433 |
| 7 | Basal transcription factors_Homo sapiens_hsa03022 | 2.36432344 |
| 8 | Homologous recombination_Homo sapiens_hsa03440 | 2.35740091 |
| 9 | Proteasome_Homo sapiens_hsa03050 | 2.27928090 |
| 10 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 2.10962946 |
| 11 | RNA polymerase_Homo sapiens_hsa03020 | 2.09740362 |
| 12 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 2.09731525 |
| 13 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 2.07549903 |
| 14 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.96384840 |
| 15 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.87472571 |
| 16 | RNA degradation_Homo sapiens_hsa03018 | 1.81307173 |
| 17 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.77984442 |
| 18 | Huntingtons disease_Homo sapiens_hsa05016 | 1.74489756 |
| 19 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.74321712 |
| 20 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.74092658 |
| 21 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.68080049 |
| 22 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.67153773 |
| 23 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.65343790 |
| 24 | Alzheimers disease_Homo sapiens_hsa05010 | 1.64903667 |
| 25 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.62780843 |
| 26 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.52018300 |
| 27 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.51051990 |
| 28 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.46284287 |
| 29 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.45108317 |
| 30 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.42216708 |
| 31 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.41532287 |
| 32 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.40725976 |
| 33 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 1.40193891 |
| 34 | Peroxisome_Homo sapiens_hsa04146 | 1.38945027 |
| 35 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 1.38925974 |
| 36 | Mismatch repair_Homo sapiens_hsa03430 | 1.38596509 |
| 37 | Olfactory transduction_Homo sapiens_hsa04740 | 1.37286583 |
| 38 | Phototransduction_Homo sapiens_hsa04744 | 1.29091039 |
| 39 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.28565932 |
| 40 | Ether lipid metabolism_Homo sapiens_hsa00565 | 1.12131999 |
| 41 | Nicotine addiction_Homo sapiens_hsa05033 | 1.11155809 |
| 42 | Regulation of autophagy_Homo sapiens_hsa04140 | 1.05704014 |
| 43 | Fatty acid metabolism_Homo sapiens_hsa01212 | 1.02166981 |
| 44 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.01295244 |
| 45 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.99420904 |
| 46 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.97657940 |
| 47 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.97607465 |
| 48 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.96037704 |
| 49 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.95707428 |
| 50 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.92744999 |
| 51 | RNA transport_Homo sapiens_hsa03013 | 0.87274944 |
| 52 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.86253427 |
| 53 | Retinol metabolism_Homo sapiens_hsa00830 | 0.84895499 |
| 54 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.83649012 |
| 55 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.83385273 |
| 56 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 0.80811988 |
| 57 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.80201808 |
| 58 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.77706157 |
| 59 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.76477450 |
| 60 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.76067101 |
| 61 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.75980445 |
| 62 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.73167309 |
| 63 | Metabolic pathways_Homo sapiens_hsa01100 | 0.72929373 |
| 64 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.72540494 |
| 65 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.71196386 |
| 66 | Insulin secretion_Homo sapiens_hsa04911 | 0.70399373 |
| 67 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.68799161 |
| 68 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.66165856 |
| 69 | Purine metabolism_Homo sapiens_hsa00230 | 0.65852933 |
| 70 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.65415036 |
| 71 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.60967701 |
| 72 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.59926587 |
| 73 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.59778498 |
| 74 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.55606681 |
| 75 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.55012854 |
| 76 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.54565520 |
| 77 | Taste transduction_Homo sapiens_hsa04742 | 0.54036501 |
| 78 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.53263219 |
| 79 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.53118087 |
| 80 | DNA replication_Homo sapiens_hsa03030 | 0.51103946 |
| 81 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.50256277 |
| 82 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.49267750 |
| 83 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.46809562 |
| 84 | Glutamatergic synapse_Homo sapiens_hsa04724 | 0.45469376 |
| 85 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.40833441 |
| 86 | Sulfur relay system_Homo sapiens_hsa04122 | 0.40682832 |
| 87 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.38516939 |
| 88 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.38395475 |
| 89 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.37992150 |
| 90 | Morphine addiction_Homo sapiens_hsa05032 | 0.37524860 |
| 91 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.35134124 |
| 92 | Base excision repair_Homo sapiens_hsa03410 | 0.34340321 |
| 93 | ABC transporters_Homo sapiens_hsa02010 | 0.33743498 |
| 94 | GABAergic synapse_Homo sapiens_hsa04727 | 0.33663978 |
| 95 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.33387354 |
| 96 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.31267345 |
| 97 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.31135347 |
| 98 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.30652806 |
| 99 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.29372753 |
| 100 | Cell cycle_Homo sapiens_hsa04110 | 0.28873269 |

