Rank | Gene Set | Z-score |
---|---|---|
1 | mitotic metaphase plate congression (GO:0007080) | 4.71509315 |
2 | mitotic chromosome condensation (GO:0007076) | 4.44675793 |
3 | metaphase plate congression (GO:0051310) | 4.17967097 |
4 | proteasome assembly (GO:0043248) | 4.11643011 |
5 | establishment of chromosome localization (GO:0051303) | 3.91905747 |
6 | mitotic nuclear envelope disassembly (GO:0007077) | 3.90707283 |
7 | CENP-A containing nucleosome assembly (GO:0034080) | 3.90283033 |
8 | attachment of spindle microtubules to kinetochore (GO:0008608) | 3.87733386 |
9 | DNA double-strand break processing (GO:0000729) | 3.85731404 |
10 | chromatin remodeling at centromere (GO:0031055) | 3.83881799 |
11 | nuclear pore complex assembly (GO:0051292) | 3.79042876 |
12 | nuclear pore organization (GO:0006999) | 3.75502275 |
13 | protein localization to kinetochore (GO:0034501) | 3.74113365 |
14 | DNA replication-independent nucleosome assembly (GO:0006336) | 3.73219669 |
15 | DNA replication-independent nucleosome organization (GO:0034724) | 3.73219669 |
16 | membrane disassembly (GO:0030397) | 3.72955026 |
17 | nuclear envelope disassembly (GO:0051081) | 3.72955026 |
18 | meiotic chromosome segregation (GO:0045132) | 3.71329576 |
19 | DNA replication checkpoint (GO:0000076) | 3.68672932 |
20 | mitotic sister chromatid cohesion (GO:0007064) | 3.68386032 |
21 | cullin deneddylation (GO:0010388) | 3.62570260 |
22 | kinetochore organization (GO:0051383) | 3.58819190 |
23 | regulation of spindle organization (GO:0090224) | 3.58009470 |
24 | protein localization to chromosome, centromeric region (GO:0071459) | 3.57730722 |
25 | regulation of helicase activity (GO:0051095) | 3.40598285 |
26 | regulation of sister chromatid cohesion (GO:0007063) | 3.33318860 |
27 | ribosome assembly (GO:0042255) | 3.31892555 |
28 | regulation of attachment of spindle microtubules to kinetochore (GO:0051988) | 3.31124728 |
29 | protein deneddylation (GO:0000338) | 3.29879653 |
30 | histone exchange (GO:0043486) | 3.28115923 |
31 | DNA ligation (GO:0006266) | 3.26725402 |
32 | spindle checkpoint (GO:0031577) | 3.26419329 |
33 | DNA replication initiation (GO:0006270) | 3.24206617 |
34 | positive regulation of mitotic metaphase/anaphase transition (GO:0045842) | 3.24058951 |
35 | positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101) | 3.24058951 |
36 | positive regulation of mitotic sister chromatid separation (GO:1901970) | 3.24058951 |
37 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.22975844 |
38 | negative regulation of DNA recombination (GO:0045910) | 3.15665406 |
39 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.15434963 |
40 | regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083) | 3.13582045 |
41 | regulation of mitotic metaphase/anaphase transition (GO:0030071) | 3.13527463 |
42 | regulation of metaphase/anaphase transition of cell cycle (GO:1902099) | 3.13412860 |
43 | regulation of chromosome segregation (GO:0051983) | 3.13258378 |
44 | kinetochore assembly (GO:0051382) | 3.11981575 |
45 | positive regulation of gamma-delta T cell activation (GO:0046645) | 3.10941572 |
46 | folic acid-containing compound biosynthetic process (GO:0009396) | 3.10775198 |
47 | negative regulation of mitotic sister chromatid separation (GO:2000816) | 3.09180709 |
48 | negative regulation of mitotic sister chromatid segregation (GO:0033048) | 3.09180709 |
49 | negative regulation of mitotic metaphase/anaphase transition (GO:0045841) | 3.09180709 |
50 | negative regulation of sister chromatid segregation (GO:0033046) | 3.09180709 |
51 | negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100) | 3.09160245 |
52 | spindle assembly checkpoint (GO:0071173) | 3.08633896 |
53 | DNA replication-dependent nucleosome assembly (GO:0006335) | 3.07847325 |
54 | DNA replication-dependent nucleosome organization (GO:0034723) | 3.07847325 |
55 | mitotic sister chromatid segregation (GO:0000070) | 3.07288231 |
56 | protein localization to chromosome (GO:0034502) | 3.06923031 |
57 | regulation of mitotic spindle organization (GO:0060236) | 3.06751975 |
58 | somatic diversification of immunoglobulins involved in immune response (GO:0002208) | 3.06554765 |
59 | isotype switching (GO:0045190) | 3.06554765 |
60 | somatic recombination of immunoglobulin genes involved in immune response (GO:0002204) | 3.06554765 |
61 | mitotic G2/M transition checkpoint (GO:0044818) | 3.05983979 |
62 | mitotic spindle assembly checkpoint (GO:0007094) | 3.05875876 |
63 | negative regulation of chromosome segregation (GO:0051985) | 3.04775947 |
64 | monoubiquitinated protein deubiquitination (GO:0035520) | 3.04461494 |
65 | DNA strand elongation involved in DNA replication (GO:0006271) | 3.02852819 |
66 | positive regulation of chromosome segregation (GO:0051984) | 3.02640644 |
67 | sister chromatid segregation (GO:0000819) | 3.02192122 |
68 | histone H2A monoubiquitination (GO:0035518) | 3.01316381 |
69 | negative regulation of retinoic acid receptor signaling pathway (GO:0048387) | 3.00659276 |
70 | mitotic spindle checkpoint (GO:0071174) | 3.00105103 |
71 | chromosome segregation (GO:0007059) | 2.99463221 |
72 | protein K6-linked ubiquitination (GO:0085020) | 2.97553640 |
73 | neutrophil activation involved in immune response (GO:0002283) | 2.97285371 |
74 | chromatin assembly or disassembly (GO:0006333) | 2.96005133 |
75 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 2.95418154 |
76 | telomere maintenance via recombination (GO:0000722) | 2.93677010 |
77 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 2.93436191 |
78 | regulation of sister chromatid segregation (GO:0033045) | 2.93028644 |
79 | regulation of mitotic sister chromatid separation (GO:0010965) | 2.93028644 |
80 | regulation of mitotic sister chromatid segregation (GO:0033047) | 2.93028644 |
81 | regulation of centrosome cycle (GO:0046605) | 2.92705696 |
82 | nuclear envelope organization (GO:0006998) | 2.92577632 |
83 | DNA unwinding involved in DNA replication (GO:0006268) | 2.90400036 |
84 | DNA strand elongation (GO:0022616) | 2.90215280 |
85 | regulation of centriole replication (GO:0046599) | 2.89676755 |
86 | mitotic G2 DNA damage checkpoint (GO:0007095) | 2.88386123 |
87 | mitotic recombination (GO:0006312) | 2.87639144 |
88 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 2.87001943 |
89 | negative regulation of ligase activity (GO:0051352) | 2.87001943 |
90 | pore complex assembly (GO:0046931) | 2.81943311 |
91 | telomere maintenance via semi-conservative replication (GO:0032201) | 2.81399159 |
92 | regulation of telomere maintenance via telomerase (GO:0032210) | 2.79611343 |
93 | positive regulation of granulocyte differentiation (GO:0030854) | 2.79118928 |
94 | regulation of double-strand break repair via homologous recombination (GO:0010569) | 2.78015731 |
95 | establishment of integrated proviral latency (GO:0075713) | 2.77597412 |
96 | regulation of histone H3-K27 methylation (GO:0061085) | 2.76562714 |
97 | maturation of 5.8S rRNA (GO:0000460) | 2.76042718 |
98 | histone mRNA catabolic process (GO:0071044) | 2.74911593 |
99 | DNA damage induced protein phosphorylation (GO:0006975) | 2.72960561 |
100 | regulation of B cell receptor signaling pathway (GO:0050855) | 2.72631218 |
101 | purine nucleobase biosynthetic process (GO:0009113) | 2.72417176 |
102 | DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 cla | 2.68206148 |
103 | sister chromatid cohesion (GO:0007062) | 2.65354773 |
104 | IMP metabolic process (GO:0046040) | 2.64662979 |
105 | negative regulation of meiosis (GO:0045835) | 2.62030394 |
106 | RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503) | 2.60688933 |
107 | DNA damage response, signal transduction resulting in transcription (GO:0042772) | 2.59979065 |
108 | DNA catabolic process, exonucleolytic (GO:0000738) | 2.59958629 |
109 | positive regulation of interleukin-2 biosynthetic process (GO:0045086) | 2.59801431 |
110 | double-strand break repair via nonhomologous end joining (GO:0006303) | 2.58492630 |
111 | non-recombinational repair (GO:0000726) | 2.58492630 |
112 | somatic cell DNA recombination (GO:0016444) | 2.57807133 |
113 | somatic diversification of immune receptors via germline recombination within a single locus (GO:000 | 2.57807133 |
114 | dosage compensation (GO:0007549) | 2.57791821 |
115 | negative regulation of histone methylation (GO:0031061) | 2.57713147 |
116 | ATP-dependent chromatin remodeling (GO:0043044) | 2.56705389 |
117 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 2.55786167 |
118 | Arp2/3 complex-mediated actin nucleation (GO:0034314) | 2.55433825 |
119 | translesion synthesis (GO:0019985) | 2.53651470 |
120 | histone mRNA metabolic process (GO:0008334) | 2.52985013 |
121 | regulation of mitotic spindle checkpoint (GO:1903504) | 2.52871405 |
122 | regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266) | 2.52871405 |
123 | histone H2A ubiquitination (GO:0033522) | 2.52857533 |
124 | IMP biosynthetic process (GO:0006188) | 2.52596452 |
125 | positive regulation of mitochondrial membrane permeability involved in apoptotic process (GO:1902110 | 2.52479731 |
126 | mitochondrial outer membrane permeabilization involved in programmed cell death (GO:1902686) | 2.52479731 |
127 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 2.51991452 |
128 | telomere maintenance via telomere lengthening (GO:0010833) | 2.51630625 |
129 | organelle disassembly (GO:1903008) | 2.50865968 |
130 | protein neddylation (GO:0045116) | 2.49680415 |
131 | N-terminal protein amino acid acetylation (GO:0006474) | 2.49099999 |
132 | DNA duplex unwinding (GO:0032508) | 2.47179521 |
133 | piRNA metabolic process (GO:0034587) | 2.46928694 |
134 | positive regulation of ligase activity (GO:0051351) | 2.46881073 |
135 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 2.46526689 |
136 | negative regulation of mitosis (GO:0045839) | 2.46019672 |
137 | DNA geometric change (GO:0032392) | 2.45691406 |
138 | nuclear-transcribed mRNA poly(A) tail shortening (GO:0000289) | 2.45332462 |
139 | negative regulation of cell division (GO:0051782) | 2.43978142 |
140 | positive regulation of B cell differentiation (GO:0045579) | 2.43807218 |
141 | regulation of cellular amino acid metabolic process (GO:0006521) | 2.43585016 |
142 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 2.42986806 |
143 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 2.42986806 |
144 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 2.42986806 |
145 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 2.42361396 |
146 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 2.42361396 |
147 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 2.41296705 |
148 | regulation of ubiquitin-protein transferase activity (GO:0051438) | 2.41275189 |
149 | negative regulation of nuclear division (GO:0051784) | 2.41117234 |
150 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 2.40972305 |
151 | somatic diversification of immune receptors (GO:0002200) | 2.40452796 |
152 | regulation of chromatin silencing (GO:0031935) | 2.39920331 |
153 | B cell mediated immunity (GO:0019724) | 2.39877136 |
154 | positive regulation of alpha-beta T cell proliferation (GO:0046641) | 2.38213853 |
155 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 2.36564973 |
156 | establishment of viral latency (GO:0019043) | 2.36222861 |
157 | antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590) | 2.35150603 |
158 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 2.34738284 |
159 | regulation of ligase activity (GO:0051340) | 2.34379780 |
Rank | Gene Set | Z-score |
---|---|---|
1 | E2F7_22180533_ChIP-Seq_HELA_Human | 8.75232737 |
2 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 5.14354970 |
3 | * E2F4_17652178_ChIP-ChIP_JURKAT_Human | 3.75926033 |
4 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 3.52886552 |
5 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 3.30183355 |
6 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 3.06149023 |
7 | AR_21909140_ChIP-Seq_LNCAP_Human | 2.70893138 |
8 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 2.55704168 |
9 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 2.32172909 |
10 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 2.25517532 |
11 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 2.23803443 |
12 | * KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 2.22572311 |
13 | * NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 2.10349704 |
14 | * GABP_17652178_ChIP-ChIP_JURKAT_Human | 2.08197666 |
15 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 2.07534434 |
16 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 2.07061385 |
17 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 2.04635507 |
18 | * MYC_19030024_ChIP-ChIP_MESCs_Mouse | 2.00793783 |
19 | * POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.92401892 |
20 | MYC_22102868_ChIP-Seq_BL_Human | 1.91624031 |
21 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.87613167 |
22 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.87481808 |
23 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.87090470 |
24 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.86229371 |
25 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 1.79730199 |
26 | * MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.79440375 |
27 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.78878955 |
28 | * ELK1_19687146_ChIP-ChIP_HELA_Human | 1.67848914 |
29 | * FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.67495978 |
30 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.63758468 |
31 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.62947121 |
32 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 1.61247087 |
33 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.60602091 |
34 | * SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.60459528 |
35 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.60394051 |
36 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.57481260 |
37 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 1.55352301 |
38 | * ZFX_18555785_ChIP-Seq_MESCs_Mouse | 1.54307520 |
39 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.51498019 |
40 | EWS_26573619_Chip-Seq_HEK293_Human | 1.50098470 |
41 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.49519844 |
42 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.48733981 |
43 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.48525909 |
44 | * SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.47970711 |
45 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.47232327 |
46 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.46314893 |
47 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 1.43034475 |
48 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 1.41330041 |
49 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.41151544 |
50 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 1.41080575 |
51 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 1.39502983 |
52 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.39089355 |
53 | * TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.38837180 |
54 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.38729035 |
55 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.38497850 |
56 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.38382007 |
57 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.38273585 |
58 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.38202736 |
59 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.36942794 |
60 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 1.36176391 |
61 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.35254194 |
62 | KLF2_18264089_ChIP-ChIP_MESCs_Mouse | 1.34449532 |
63 | KLF5_18264089_ChIP-ChIP_MESCs_Mouse | 1.34449532 |
64 | KLF4_18264089_ChIP-ChIP_MESCs_Mouse | 1.34449532 |
65 | KDM5A_27292631_Chip-Seq_BREAST_Human | 1.33277217 |
66 | PRDM5_23873026_ChIP-Seq_MEFs_Mouse | 1.32803709 |
67 | MYB_26560356_Chip-Seq_TH2_Human | 1.32664611 |
68 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.31496213 |
69 | RUNX1_17652178_ChIP-ChIP_JURKAT_Human | 1.30894844 |
70 | TFEB_21752829_ChIP-Seq_HELA_Human | 1.28946675 |
71 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.28854104 |
72 | * SPI1_23547873_ChIP-Seq_NB4_Human | 1.26697674 |
73 | * TTF2_22483619_ChIP-Seq_HELA_Human | 1.26599592 |
74 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.24932263 |
75 | FUS_26573619_Chip-Seq_HEK293_Human | 1.24292032 |
76 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.23627642 |
77 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.23370324 |
78 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 1.23081862 |
79 | E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 1.22423137 |
80 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.22114735 |
81 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 1.21494487 |
82 | MYB_26560356_Chip-Seq_TH1_Human | 1.20932737 |
83 | * KLF4_18555785_ChIP-Seq_MESCs_Mouse | 1.20466552 |
84 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 1.19427021 |
85 | * CREM_20920259_ChIP-Seq_GC1-SPG_Mouse | 1.18409327 |
86 | * PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.17910743 |
87 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.16910182 |
88 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.13847495 |
89 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.12888957 |
90 | * FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.11992674 |
91 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 1.07988824 |
92 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.07740079 |
93 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 1.07574170 |
94 | GATA3_26560356_Chip-Seq_TH2_Human | 1.07437952 |
95 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 1.04492915 |
96 | * GATA3_27048872_Chip-Seq_THYMUS_Human | 1.02859909 |
97 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 1.02708727 |
98 | * GFI1B_20887958_ChIP-Seq_HPC-7_Mouse | 1.02121783 |
99 | WT1_19549856_ChIP-ChIP_CCG9911_Human | 1.01710788 |
100 | DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 1.01138130 |
101 | * SALL4_22934838_ChIP-ChIP_CD34+_Human | 0.98698904 |
102 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 0.98166723 |
103 | CNOT3_19339689_ChIP-ChIP_MESCs_Mouse | 0.97835387 |
104 | FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human | 0.97781322 |
105 | RUNX_20019798_ChIP-Seq_JUKART_Human | 0.96751075 |
106 | IRF1_19129219_ChIP-ChIP_H3396_Human | 0.96072130 |
107 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 0.94710867 |
108 | UTX_26944678_Chip-Seq_JUKART_Human | 0.94351917 |
109 | * CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 0.93618441 |
110 | RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse | 0.91585173 |
111 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 0.90855023 |
112 | CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat | 0.90657304 |
113 | ZNF274_21170338_ChIP-Seq_K562_Hela | 0.89963729 |
114 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 0.89883724 |
115 | * SRF_21415370_ChIP-Seq_HL-1_Mouse | 0.89781470 |
116 | P300_19829295_ChIP-Seq_ESCs_Human | 0.89555724 |
117 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 0.89205607 |
118 | SOX2_19030024_ChIP-ChIP_MESCs_Mouse | 0.88976841 |
119 | MAF_26560356_Chip-Seq_TH1_Human | 0.88752238 |
120 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 0.88284089 |
121 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 0.87006165 |
122 | CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse | 0.86268857 |
123 | MYC_18940864_ChIP-ChIP_HL60_Human | 0.84449580 |
124 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 0.84212228 |
125 | * HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 0.82370459 |
126 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 0.80575387 |
127 | * RUNX1_22412390_ChIP-Seq_EML_Mouse | 0.79961145 |
128 | GATA1_22025678_ChIP-Seq_K562_Human | 0.79825774 |
129 | VDR_21846776_ChIP-Seq_THP-1_Human | 0.79220945 |
130 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 0.78764019 |
131 | NKX2-5_21415370_ChIP-Seq_HL-1_Mouse | 0.78242954 |
132 | * SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 0.78197643 |
133 | NANOG_18700969_ChIP-ChIP_MESCs_Mouse | 0.77241203 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0003693_abnormal_embryo_hatching | 4.44291429 |
2 | MP0010094_abnormal_chromosome_stability | 3.53982702 |
3 | MP0003111_abnormal_nucleus_morphology | 3.34351003 |
4 | MP0003077_abnormal_cell_cycle | 3.22885143 |
5 | MP0004957_abnormal_blastocyst_morpholog | 3.13704367 |
6 | MP0008057_abnormal_DNA_replication | 2.84703434 |
7 | MP0003221_abnormal_cardiomyocyte_apopto | 2.79063493 |
8 | MP0002009_preneoplasia | 2.75884626 |
9 | MP0008007_abnormal_cellular_replicative | 2.42641376 |
10 | MP0010352_gastrointestinal_tract_polyps | 2.20762437 |
11 | MP0008058_abnormal_DNA_repair | 2.19855499 |
12 | MP0003763_abnormal_thymus_physiology | 2.01318215 |
13 | MP0002396_abnormal_hematopoietic_system | 1.96129364 |
14 | MP0009697_abnormal_copulation | 1.91854923 |
15 | MP0008260_abnormal_autophagy | 1.81330078 |
16 | MP0010307_abnormal_tumor_latency | 1.77211927 |
17 | MP0000350_abnormal_cell_proliferation | 1.74752885 |
18 | MP0008932_abnormal_embryonic_tissue | 1.74427825 |
19 | MP0003718_maternal_effect | 1.73393419 |
20 | MP0008877_abnormal_DNA_methylation | 1.71042167 |
21 | MP0003123_paternal_imprinting | 1.70393486 |
22 | MP0005075_abnormal_melanosome_morpholog | 1.69970399 |
23 | MP0002254_reproductive_system_inflammat | 1.65266067 |
24 | MP0000490_abnormal_crypts_of | 1.64128962 |
25 | MP0001730_embryonic_growth_arrest | 1.63903456 |
26 | MP0005076_abnormal_cell_differentiation | 1.63507666 |
27 | MP0006082_CNS_inflammation | 1.60299292 |
28 | MP0004808_abnormal_hematopoietic_stem | 1.59784516 |
29 | MP0010234_abnormal_vibrissa_follicle | 1.54296143 |
30 | MP0002006_tumorigenesis | 1.42757773 |
31 | MP0000569_abnormal_digit_pigmentation | 1.42178591 |
32 | MP0002019_abnormal_tumor_incidence | 1.39569099 |
33 | MP0001697_abnormal_embryo_size | 1.38625117 |
34 | MP0006054_spinal_hemorrhage | 1.38089571 |
35 | MP0005397_hematopoietic_system_phenotyp | 1.33536197 |
36 | MP0001545_abnormal_hematopoietic_system | 1.33536197 |
37 | MP0002398_abnormal_bone_marrow | 1.32697646 |
38 | MP0001835_abnormal_antigen_presentation | 1.32444779 |
39 | MP0000703_abnormal_thymus_morphology | 1.30954448 |
40 | MP0005387_immune_system_phenotype | 1.30773704 |
41 | MP0005380_embryogenesis_phenotype | 1.30668672 |
42 | MP0001672_abnormal_embryogenesis/_devel | 1.30668672 |
43 | MP0002877_abnormal_melanocyte_morpholog | 1.27705156 |
44 | MP0003656_abnormal_erythrocyte_physiolo | 1.27531669 |
45 | MP0003300_gastrointestinal_ulcer | 1.26468580 |
46 | MP0009333_abnormal_splenocyte_physiolog | 1.24155744 |
47 | MP0002166_altered_tumor_susceptibility | 1.23566032 |
48 | MP0002148_abnormal_hypersensitivity_rea | 1.21896835 |
49 | MP0001800_abnormal_humoral_immune | 1.21200281 |
50 | MP0003984_embryonic_growth_retardation | 1.20535390 |
51 | MP0006035_abnormal_mitochondrial_morpho | 1.19819293 |
52 | MP0002086_abnormal_extraembryonic_tissu | 1.19378323 |
53 | MP0001119_abnormal_female_reproductive | 1.18976736 |
54 | MP0002088_abnormal_embryonic_growth/wei | 1.18367020 |
55 | MP0002796_impaired_skin_barrier | 1.16488764 |
56 | MP0000689_abnormal_spleen_morphology | 1.16248592 |
57 | MP0002085_abnormal_embryonic_tissue | 1.16070175 |
58 | MP0003436_decreased_susceptibility_to | 1.16008221 |
59 | MP0001853_heart_inflammation | 1.15899711 |
60 | MP0002722_abnormal_immune_system | 1.15561487 |
61 | MP0005671_abnormal_response_to | 1.15246336 |
62 | MP0002084_abnormal_developmental_patter | 1.14404514 |
63 | MP0000858_altered_metastatic_potential | 1.14265734 |
64 | MP0008789_abnormal_olfactory_epithelium | 1.13255862 |
65 | MP0003806_abnormal_nucleotide_metabolis | 1.13242573 |
66 | MP0001188_hyperpigmentation | 1.13082103 |
67 | MP0002102_abnormal_ear_morphology | 1.12620615 |
68 | MP0002080_prenatal_lethality | 1.10274031 |
69 | MP0004264_abnormal_extraembryonic_tissu | 1.08332246 |
70 | MP0002452_abnormal_antigen_presenting | 1.08323345 |
71 | MP0000313_abnormal_cell_death | 1.07041131 |
72 | MP0000685_abnormal_immune_system | 1.04971368 |
73 | MP0004947_skin_inflammation | 1.04786858 |
74 | MP0006036_abnormal_mitochondrial_physio | 1.03955100 |
75 | MP0003566_abnormal_cell_adhesion | 1.02602821 |
76 | MP0002405_respiratory_system_inflammati | 1.01842652 |
77 | MP0005023_abnormal_wound_healing | 1.01497713 |
78 | MP0002420_abnormal_adaptive_immunity | 1.01479088 |
79 | MP0000716_abnormal_immune_system | 1.00966251 |
80 | MP0001819_abnormal_immune_cell | 1.00936361 |
81 | MP0005000_abnormal_immune_tolerance | 0.98631433 |
82 | MP0003787_abnormal_imprinting | 0.97744106 |
83 | MP0001873_stomach_inflammation | 0.97203983 |
84 | MP0002723_abnormal_immune_serum | 0.97085916 |
85 | MP0002429_abnormal_blood_cell | 0.95981163 |
86 | MP0003786_premature_aging | 0.95556704 |
87 | MP0001915_intracranial_hemorrhage | 0.95333867 |
88 | MP0002210_abnormal_sex_determination | 0.94489316 |
89 | MP0003121_genomic_imprinting | 0.93604921 |
90 | MP0003646_muscle_fatigue | 0.93088804 |
91 | MP0005621_abnormal_cell_physiology | 0.93058563 |
92 | MP0010155_abnormal_intestine_physiology | 0.91993181 |
93 | MP0005395_other_phenotype | 0.91733499 |
94 | MP0001191_abnormal_skin_condition | 0.91595967 |
95 | MP0004197_abnormal_fetal_growth/weight/ | 0.90301696 |
96 | MP0004484_altered_response_of | 0.89385626 |
97 | MP0003724_increased_susceptibility_to | 0.88812375 |
98 | MP0005408_hypopigmentation | 0.88663745 |
99 | MP0003448_altered_tumor_morphology | 0.88203439 |
100 | MP0003699_abnormal_female_reproductive | 0.86959695 |
101 | MP0003941_abnormal_skin_development | 0.86948553 |
102 | MP0003828_pulmonary_edema | 0.86629110 |
103 | MP0000653_abnormal_sex_gland | 0.86216900 |
104 | MP0001929_abnormal_gametogenesis | 0.85237763 |
105 | MP0003705_abnormal_hypodermis_morpholog | 0.83709294 |
106 | MP0001177_atelectasis | 0.83170108 |
107 | MP0009278_abnormal_bone_marrow | 0.80509248 |
108 | MP0003453_abnormal_keratinocyte_physiol | 0.80348171 |
109 | MP0008995_early_reproductive_senescence | 0.79861154 |
110 | MP0001529_abnormal_vocalization | 0.79520243 |
111 | MP0005084_abnormal_gallbladder_morpholo | 0.79365563 |
112 | MP0002138_abnormal_hepatobiliary_system | 0.79362858 |
113 | MP0009785_altered_susceptibility_to | 0.79265116 |
114 | MP0002277_abnormal_respiratory_mucosa | 0.79026193 |
115 | MP0002132_abnormal_respiratory_system | 0.77985123 |
116 | MP0001145_abnormal_male_reproductive | 0.77940194 |
117 | MP0005501_abnormal_skin_physiology | 0.77719243 |
118 | MP0005384_cellular_phenotype | 0.77192839 |
119 | MP0000427_abnormal_hair_cycle | 0.76731950 |
120 | MP0005464_abnormal_platelet_physiology | 0.76691221 |
121 | MP0005499_abnormal_olfactory_system | 0.76587446 |
122 | MP0005394_taste/olfaction_phenotype | 0.76587446 |
123 | MP0004147_increased_porphyrin_level | 0.76469817 |
124 | MP0003890_abnormal_embryonic-extraembry | 0.76118732 |
125 | MP0002419_abnormal_innate_immunity | 0.74154853 |
126 | MP0000465_gastrointestinal_hemorrhage | 0.74011224 |
127 | MP0001845_abnormal_inflammatory_respons | 0.72469170 |
128 | MP0001293_anophthalmia | 0.70554419 |
129 | MP0005025_abnormal_response_to | 0.69778873 |
130 | MP0003567_abnormal_fetal_cardiomyocyte | 0.69341639 |
131 | MP0001790_abnormal_immune_system | 0.69126886 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Birth length less than 3rd percentile (HP:0003561) | 4.78050210 |
2 | Chromsome breakage (HP:0040012) | 3.90212356 |
3 | Stomatitis (HP:0010280) | 3.61831228 |
4 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 3.47197336 |
5 | Breast hypoplasia (HP:0003187) | 3.33161545 |
6 | B lymphocytopenia (HP:0010976) | 3.32474853 |
7 | Abnormality of the fingertips (HP:0001211) | 3.21361182 |
8 | Abnormality of B cell number (HP:0010975) | 3.09604725 |
9 | Abnormality of chromosome stability (HP:0003220) | 3.03749017 |
10 | Amyotrophic lateral sclerosis (HP:0007354) | 2.92910881 |
11 | Acute myeloid leukemia (HP:0004808) | 2.92473792 |
12 | Gonadotropin excess (HP:0000837) | 2.90886265 |
13 | Thyroiditis (HP:0100646) | 2.71085966 |
14 | Aplastic anemia (HP:0001915) | 2.67041833 |
15 | Atrophy/Degeneration involving motor neurons (HP:0007373) | 2.65167368 |
16 | Thyroid carcinoma (HP:0002890) | 2.61513627 |
17 | Facial hemangioma (HP:0000329) | 2.59490096 |
18 | Embryonal renal neoplasm (HP:0011794) | 2.57926923 |
19 | Patellar aplasia (HP:0006443) | 2.57849427 |
20 | Myelodysplasia (HP:0002863) | 2.57028404 |
21 | Nephroblastoma (Wilms tumor) (HP:0002667) | 2.48628413 |
22 | Abnormality of the preputium (HP:0100587) | 2.47756986 |
23 | Meckel diverticulum (HP:0002245) | 2.45440636 |
24 | Papillary thyroid carcinoma (HP:0002895) | 2.42100351 |
25 | Hypoplasia of the thymus (HP:0000778) | 2.42013670 |
26 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 2.41674400 |
27 | IgM deficiency (HP:0002850) | 2.39215887 |
28 | Oral leukoplakia (HP:0002745) | 2.38605164 |
29 | Ectopic kidney (HP:0000086) | 2.35919626 |
30 | Aplasia/Hypoplasia of the patella (HP:0006498) | 2.35534627 |
31 | Carpal bone hypoplasia (HP:0001498) | 2.30176887 |
32 | Increased IgM level (HP:0003496) | 2.27993838 |
33 | Overlapping toe (HP:0001845) | 2.27314189 |
34 | Capillary hemangiomas (HP:0005306) | 2.27188906 |
35 | Acute hepatic failure (HP:0006554) | 2.26505470 |
36 | Abnormality of the ileum (HP:0001549) | 2.25732165 |
37 | Posterior subcapsular cataract (HP:0007787) | 2.24758514 |
38 | Methylmalonic acidemia (HP:0002912) | 2.24005595 |
39 | Recurrent bacterial skin infections (HP:0005406) | 2.20530789 |
40 | Abnormality of methionine metabolism (HP:0010901) | 2.19987732 |
41 | Panhypogammaglobulinemia (HP:0003139) | 2.19748707 |
42 | Ovarian neoplasm (HP:0100615) | 2.17375676 |
43 | Hypoproteinemia (HP:0003075) | 2.14962193 |
44 | Abnormality of eosinophils (HP:0001879) | 2.14606241 |
45 | Reticulocytopenia (HP:0001896) | 2.14439641 |
46 | Flat capital femoral epiphysis (HP:0003370) | 2.12587523 |
47 | Cortical dysplasia (HP:0002539) | 2.11586835 |
48 | Autoimmune hemolytic anemia (HP:0001890) | 2.09980136 |
49 | Colon cancer (HP:0003003) | 2.09930757 |
50 | Lip pit (HP:0100267) | 2.09608323 |
51 | Recurrent viral infections (HP:0004429) | 2.08533566 |
52 | Premature ovarian failure (HP:0008209) | 2.06373976 |
53 | Prominent nose (HP:0000448) | 2.06169851 |
54 | Chronic diarrhea (HP:0002028) | 2.06005914 |
55 | Duodenal stenosis (HP:0100867) | 2.04585908 |
56 | Small intestinal stenosis (HP:0012848) | 2.04585908 |
57 | Amaurosis fugax (HP:0100576) | 2.04376341 |
58 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 2.04229994 |
59 | Prostate neoplasm (HP:0100787) | 2.03893021 |
60 | Neoplasm of the colon (HP:0100273) | 2.03057836 |
61 | Neoplasm of the small intestine (HP:0100833) | 2.02629929 |
62 | Disinhibition (HP:0000734) | 2.00107346 |
63 | Neoplasm of the pancreas (HP:0002894) | 1.99457019 |
64 | Abnormality of the musculature of the pelvis (HP:0001469) | 1.98813613 |
65 | Abnormality of the hip-girdle musculature (HP:0001445) | 1.98813613 |
66 | Leukocytosis (HP:0001974) | 1.98648152 |
67 | Abnormality of the labia minora (HP:0012880) | 1.98633326 |
68 | Thrombocytosis (HP:0001894) | 1.98404850 |
69 | Lymphoma (HP:0002665) | 1.97949663 |
70 | T lymphocytopenia (HP:0005403) | 1.97754576 |
71 | Abnormal lung lobation (HP:0002101) | 1.97534032 |
72 | Pelvic girdle muscle weakness (HP:0003749) | 1.97384051 |
73 | Medulloblastoma (HP:0002885) | 1.97051682 |
74 | Microretrognathia (HP:0000308) | 1.96471961 |
75 | Sparse lateral eyebrow (HP:0005338) | 1.96295759 |
76 | Pancreatic islet-cell hyperplasia (HP:0004510) | 1.96276049 |
77 | Abnormality of T cells (HP:0002843) | 1.96226799 |
78 | Postnatal microcephaly (HP:0005484) | 1.96001879 |
79 | Biliary tract neoplasm (HP:0100574) | 1.95368497 |
80 | Secondary amenorrhea (HP:0000869) | 1.93964220 |
81 | Abnormality of DNA repair (HP:0003254) | 1.92653901 |
82 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 1.92619409 |
83 | Abnormal protein N-linked glycosylation (HP:0012347) | 1.92619409 |
84 | Abnormal protein glycosylation (HP:0012346) | 1.92619409 |
85 | Abnormal glycosylation (HP:0012345) | 1.92619409 |
86 | Encephalitis (HP:0002383) | 1.92174257 |
87 | Sandal gap (HP:0001852) | 1.91474592 |
88 | Clubbing of toes (HP:0100760) | 1.90617343 |
89 | Abnormal spermatogenesis (HP:0008669) | 1.90576420 |
90 | Hematochezia (HP:0002573) | 1.89710194 |
91 | Combined immunodeficiency (HP:0005387) | 1.89341351 |
92 | Abnormality of T cell number (HP:0011839) | 1.89268167 |
93 | Premature graying of hair (HP:0002216) | 1.89236736 |
94 | Myositis (HP:0100614) | 1.88256378 |
95 | High pitched voice (HP:0001620) | 1.87865983 |
96 | Aseptic necrosis (HP:0010885) | 1.87532976 |
97 | Pulmonary fibrosis (HP:0002206) | 1.87215846 |
98 | Rhabdomyosarcoma (HP:0002859) | 1.86998222 |
99 | Bone marrow hypocellularity (HP:0005528) | 1.86938687 |
100 | Abnormality of T cell physiology (HP:0011840) | 1.86254431 |
101 | Blepharitis (HP:0000498) | 1.85687364 |
102 | Selective tooth agenesis (HP:0001592) | 1.84263403 |
103 | Absent radius (HP:0003974) | 1.83305196 |
104 | Rough bone trabeculation (HP:0100670) | 1.83092333 |
105 | Abnormal hair whorl (HP:0010721) | 1.81856700 |
106 | Slender long bone (HP:0003100) | 1.80526341 |
107 | Eczematoid dermatitis (HP:0000976) | 1.80481661 |
108 | Keratoconjunctivitis sicca (HP:0001097) | 1.80379097 |
109 | Abnormality of serum amino acid levels (HP:0003112) | 1.79958634 |
110 | Cellular immunodeficiency (HP:0005374) | 1.79930125 |
111 | Spondylolisthesis (HP:0003302) | 1.79108983 |
112 | Exercise-induced muscle cramps (HP:0003710) | 1.78542951 |
113 | Volvulus (HP:0002580) | 1.78517332 |
114 | Facial diplegia (HP:0001349) | 1.77771615 |
115 | Recurrent fungal infections (HP:0002841) | 1.77626892 |
116 | Sloping forehead (HP:0000340) | 1.77248681 |
117 | Neoplasm of the rectum (HP:0100743) | 1.76463848 |
118 | Cafe-au-lait spot (HP:0000957) | 1.76183632 |
119 | Microvesicular hepatic steatosis (HP:0001414) | 1.75931974 |
120 | Multiple enchondromatosis (HP:0005701) | 1.75754858 |
121 | Neoplasm of the adrenal gland (HP:0100631) | 1.75577708 |
122 | Deep philtrum (HP:0002002) | 1.75501376 |
123 | Long clavicles (HP:0000890) | 1.74608104 |
124 | Entropion (HP:0000621) | 1.74566035 |
125 | Broad palm (HP:0001169) | 1.74114268 |
126 | Abnormal biliary tract morphology (HP:0012440) | 1.73846659 |
127 | Basal cell carcinoma (HP:0002671) | 1.73184981 |
128 | Granulocytopenia (HP:0001913) | 1.72795884 |
129 | Abnormality of the vitamin B12 metabolism (HP:0004341) | 1.71684222 |
130 | Severe combined immunodeficiency (HP:0004430) | 1.71678075 |
131 | Urticaria (HP:0001025) | 1.71653994 |
132 | Erythroderma (HP:0001019) | 1.69416463 |
133 | Agnosia (HP:0010524) | 1.69093099 |
134 | Retrobulbar optic neuritis (HP:0100654) | 1.68884517 |
135 | Optic neuritis (HP:0100653) | 1.68884517 |
136 | Short 4th metacarpal (HP:0010044) | 1.68881237 |
137 | Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042) | 1.68881237 |
138 | Median cleft lip (HP:0000161) | 1.68645244 |
139 | IgA deficiency (HP:0002720) | 1.68614432 |
140 | Autoimmune thrombocytopenia (HP:0001973) | 1.68499367 |
141 | Leukopenia (HP:0001882) | 1.68414825 |
142 | Abnormality of the anterior horn cell (HP:0006802) | 1.68120704 |
143 | Degeneration of anterior horn cells (HP:0002398) | 1.68120704 |
144 | Malignant gastrointestinal tract tumors (HP:0006749) | 1.67918014 |
145 | Gastrointestinal carcinoma (HP:0002672) | 1.67918014 |
146 | Bicuspid aortic valve (HP:0001647) | 1.67275232 |
147 | Osteomyelitis (HP:0002754) | 1.67008154 |
148 | Hypochromic microcytic anemia (HP:0004840) | 1.67005965 |
149 | Aplasia involving forearm bones (HP:0009822) | 1.66889146 |
150 | Absent forearm bone (HP:0003953) | 1.66889146 |
151 | Ankle contracture (HP:0006466) | 1.66343129 |
152 | Absent thumb (HP:0009777) | 1.66330697 |
153 | Recurrent abscess formation (HP:0002722) | 1.66236299 |
154 | Abnormality of the prostate (HP:0008775) | 1.66152219 |
155 | Abnormality of the carotid arteries (HP:0005344) | 1.66084466 |
156 | Long eyelashes (HP:0000527) | 1.65848474 |
157 | Type I transferrin isoform profile (HP:0003642) | 1.65729990 |
158 | Increased density of long bones (HP:0006392) | 1.65462179 |
159 | Abnormality of the calcaneus (HP:0008364) | 1.65431942 |
160 | Eosinophilia (HP:0001880) | 1.65419609 |
161 | Curly hair (HP:0002212) | 1.64991979 |
162 | IgG deficiency (HP:0004315) | 1.64388710 |
Rank | Gene Set | Z-score |
---|---|---|
1 | TRIM28 | 4.55844665 |
2 | CDC7 | 3.55488901 |
3 | BCR | 3.31374604 |
4 | PLK4 | 3.25363762 |
5 | MST4 | 3.21933269 |
6 | SIK3 | 3.10830895 |
7 | ACVR1B | 2.93055765 |
8 | BUB1 | 2.56497959 |
9 | EIF2AK1 | 2.51621722 |
10 | ERBB3 | 2.48125708 |
11 | RPS6KA4 | 2.46347758 |
12 | LATS1 | 2.39369242 |
13 | WEE1 | 2.38071466 |
14 | STK10 | 2.32574708 |
15 | TTK | 2.27957394 |
16 | NEK2 | 2.26283688 |
17 | MAP4K2 | 2.08979882 |
18 | TSSK6 | 2.02604966 |
19 | BRSK2 | 2.00411490 |
20 | CDK19 | 1.95790612 |
21 | EEF2K | 1.95294078 |
22 | MAPKAPK3 | 1.80721937 |
23 | BMPR2 | 1.76979592 |
24 | JAK3 | 1.71226992 |
25 | SRPK1 | 1.64391287 |
26 | TAOK3 | 1.63871391 |
27 | IRAK3 | 1.62514797 |
28 | PBK | 1.61577763 |
29 | DYRK3 | 1.60163793 |
30 | SCYL2 | 1.53572880 |
31 | MAP3K8 | 1.52453352 |
32 | PLK1 | 1.51807081 |
33 | EIF2AK3 | 1.51556939 |
34 | RPS6KB2 | 1.51242153 |
35 | STK3 | 1.49745824 |
36 | BRD4 | 1.47258144 |
37 | AURKB | 1.42668708 |
38 | WNK3 | 1.37850987 |
39 | MELK | 1.34717266 |
40 | TESK2 | 1.34038676 |
41 | ATR | 1.32867002 |
42 | MAP4K1 | 1.32078009 |
43 | RAF1 | 1.27755655 |
44 | CHEK2 | 1.23771368 |
45 | NEK9 | 1.16264710 |
46 | MAP3K6 | 1.15426557 |
47 | ZAK | 1.15357076 |
48 | TGFBR1 | 1.14908488 |
49 | CDK12 | 1.14398330 |
50 | KDR | 1.12823890 |
51 | TYK2 | 1.12531535 |
52 | FLT3 | 1.12262956 |
53 | KSR2 | 1.11625754 |
54 | MAP3K13 | 1.10280959 |
55 | CDK8 | 1.08953349 |
56 | NUAK1 | 1.07440920 |
57 | LATS2 | 1.05566443 |
58 | NLK | 1.01694473 |
59 | FRK | 1.01411024 |
60 | CDK9 | 1.00749461 |
61 | CDK4 | 1.00460509 |
62 | EPHA2 | 0.97977694 |
63 | VRK1 | 0.97529735 |
64 | PLK3 | 0.96615979 |
65 | TEC | 0.93879117 |
66 | BCKDK | 0.92184208 |
67 | STK38L | 0.91565178 |
68 | MAP3K12 | 0.90792969 |
69 | TXK | 0.90229968 |
70 | ZAP70 | 0.89188573 |
71 | MAP3K4 | 0.88979214 |
72 | ERBB4 | 0.88370517 |
73 | TAOK1 | 0.87342392 |
74 | BRAF | 0.86460045 |
75 | CDK7 | 0.86055837 |
76 | NEK1 | 0.85605033 |
77 | LRRK2 | 0.85022492 |
78 | FGR | 0.84339446 |
79 | ATM | 0.83557045 |
80 | CHEK1 | 0.82741208 |
81 | CSNK1G1 | 0.81753170 |
82 | CDK6 | 0.81174373 |
83 | BRSK1 | 0.80095046 |
84 | PASK | 0.79452005 |
85 | PIM1 | 0.77914187 |
86 | CSNK1G3 | 0.77740327 |
87 | MAP3K3 | 0.75854140 |
88 | CSNK1A1L | 0.75090268 |
89 | MAP3K5 | 0.74861016 |
90 | RIPK4 | 0.73706164 |
91 | STK4 | 0.73040893 |
92 | ITK | 0.70972559 |
93 | BMPR1B | 0.70580361 |
94 | EGFR | 0.69201875 |
95 | CHUK | 0.68380606 |
96 | IRAK4 | 0.67110004 |
97 | YES1 | 0.66921986 |
98 | CLK1 | 0.66034583 |
99 | AURKA | 0.63953961 |
100 | CSK | 0.62256473 |
101 | PKN2 | 0.61092698 |
102 | AKT3 | 0.60438251 |
103 | TNIK | 0.60015955 |
104 | EPHA3 | 0.59621414 |
105 | MAP3K10 | 0.59515575 |
106 | CSNK1G2 | 0.59393540 |
107 | MARK3 | 0.57747876 |
108 | FES | 0.57475219 |
109 | FGFR3 | 0.56773850 |
110 | MKNK1 | 0.55775050 |
111 | MAP2K7 | 0.54828548 |
112 | TRPM7 | 0.54742994 |
113 | BTK | 0.54162254 |
114 | EIF2AK2 | 0.53489188 |
115 | STK24 | 0.53118038 |
116 | LCK | 0.52939341 |
117 | MKNK2 | 0.52860645 |
118 | GRK6 | 0.52624640 |
119 | HCK | 0.52162449 |
120 | IRAK1 | 0.52104449 |
121 | PIK3CG | 0.50550475 |
122 | MATK | 0.50006031 |
123 | JAK2 | 0.49384244 |
124 | OXSR1 | 0.49372526 |
125 | MOS | 0.49165547 |
126 | STK16 | 0.49162572 |
127 | LYN | 0.48943130 |
128 | CDK2 | 0.48598679 |
129 | RPS6KA5 | 0.48238370 |
130 | PAK4 | 0.48088288 |
131 | NEK6 | 0.47940847 |
132 | KIT | 0.47292654 |
133 | KSR1 | 0.47190048 |
134 | PLK2 | 0.46929177 |
135 | MAP2K3 | 0.46397949 |
136 | SYK | 0.45607420 |
137 | TBK1 | 0.44239905 |
138 | MAP3K14 | 0.43722347 |
139 | IKBKE | 0.43112699 |
140 | JAK1 | 0.42019543 |
141 | TAOK2 | 0.41680851 |
142 | TESK1 | 0.41548852 |
143 | TLK1 | 0.41235587 |
144 | MAPK11 | 0.38914095 |
145 | HIPK2 | 0.36906337 |
146 | CAMKK2 | 0.36457506 |
Rank | Gene Set | Z-score |
---|---|---|
1 | DNA replication_Homo sapiens_hsa03030 | 3.42964717 |
2 | Cell cycle_Homo sapiens_hsa04110 | 3.21840748 |
3 | Mismatch repair_Homo sapiens_hsa03430 | 2.74974629 |
4 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.58095525 |
5 | RNA transport_Homo sapiens_hsa03013 | 2.42954655 |
6 | Homologous recombination_Homo sapiens_hsa03440 | 2.30691146 |
7 | RNA degradation_Homo sapiens_hsa03018 | 2.28055857 |
8 | p53 signaling pathway_Homo sapiens_hsa04115 | 2.25288281 |
9 | Base excision repair_Homo sapiens_hsa03410 | 2.22806466 |
10 | Non-homologous end-joining_Homo sapiens_hsa03450 | 2.17779041 |
11 | Nucleotide excision repair_Homo sapiens_hsa03420 | 2.06760713 |
12 | Spliceosome_Homo sapiens_hsa03040 | 2.06742830 |
13 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 2.06317102 |
14 | Allograft rejection_Homo sapiens_hsa05330 | 1.92627176 |
15 | Basal transcription factors_Homo sapiens_hsa03022 | 1.86637086 |
16 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.84110401 |
17 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.82838204 |
18 | RNA polymerase_Homo sapiens_hsa03020 | 1.78584765 |
19 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.65567654 |
20 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.59204903 |
21 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.54902527 |
22 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 1.54589450 |
23 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.53754566 |
24 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.49667526 |
25 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.46544983 |
26 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 1.45699224 |
27 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.45344601 |
28 | Asthma_Homo sapiens_hsa05310 | 1.42865796 |
29 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.39171574 |
30 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 1.36923940 |
31 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.34878856 |
32 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 1.34024785 |
33 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 1.28754797 |
34 | Viral carcinogenesis_Homo sapiens_hsa05203 | 1.27640272 |
35 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.27602538 |
36 | Pancreatic cancer_Homo sapiens_hsa05212 | 1.24570053 |
37 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 1.23500189 |
38 | Measles_Homo sapiens_hsa05162 | 1.22693858 |
39 | HTLV-I infection_Homo sapiens_hsa05166 | 1.20761891 |
40 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 1.20563178 |
41 | Proteasome_Homo sapiens_hsa03050 | 1.19462152 |
42 | Small cell lung cancer_Homo sapiens_hsa05222 | 1.17482644 |
43 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.16066926 |
44 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 1.15185901 |
45 | Regulation of autophagy_Homo sapiens_hsa04140 | 1.14196405 |
46 | Hepatitis B_Homo sapiens_hsa05161 | 1.12992266 |
47 | Legionellosis_Homo sapiens_hsa05134 | 1.12511838 |
48 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 1.11357737 |
49 | * Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 1.08900160 |
50 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 1.08134917 |
51 | Oocyte meiosis_Homo sapiens_hsa04114 | 1.04315624 |
52 | Shigellosis_Homo sapiens_hsa05131 | 1.02405799 |
53 | Apoptosis_Homo sapiens_hsa04210 | 1.00783318 |
54 | Leishmaniasis_Homo sapiens_hsa05140 | 1.00537085 |
55 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 1.00401033 |
56 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.98012356 |
57 | Influenza A_Homo sapiens_hsa05164 | 0.97132667 |
58 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.96504160 |
59 | Colorectal cancer_Homo sapiens_hsa05210 | 0.96295627 |
60 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.94437582 |
61 | Thyroid cancer_Homo sapiens_hsa05216 | 0.94358432 |
62 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.94268881 |
63 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.92186238 |
64 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.91791809 |
65 | * Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.91772955 |
66 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.91454426 |
67 | Adherens junction_Homo sapiens_hsa04520 | 0.89891511 |
68 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.89530750 |
69 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.88889718 |
70 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.86811311 |
71 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.82622221 |
72 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.81651314 |
73 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.81328350 |
74 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.81006262 |
75 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.78129537 |
76 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.76931754 |
77 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.76767247 |
78 | Circadian rhythm_Homo sapiens_hsa04710 | 0.74830786 |
79 | Viral myocarditis_Homo sapiens_hsa05416 | 0.73901885 |
80 | Osteoclast differentiation_Homo sapiens_hsa04380 | 0.73830005 |
81 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.71213078 |
82 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 0.70902752 |
83 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.70788911 |
84 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.69929804 |
85 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.69887068 |
86 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.68646344 |
87 | Purine metabolism_Homo sapiens_hsa00230 | 0.68014713 |
88 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.67074923 |
89 | Salmonella infection_Homo sapiens_hsa05132 | 0.66444450 |
90 | Ribosome_Homo sapiens_hsa03010 | 0.65839069 |
91 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.65819418 |
92 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.64976198 |
93 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 0.64131937 |
94 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.63810579 |
95 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.61613389 |
96 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.61222376 |
97 | Bladder cancer_Homo sapiens_hsa05219 | 0.57173982 |
98 | Protein export_Homo sapiens_hsa03060 | 0.56298383 |
99 | Prostate cancer_Homo sapiens_hsa05215 | 0.55977749 |
100 | Malaria_Homo sapiens_hsa05144 | 0.53363716 |
101 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.53016738 |
102 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.52412405 |
103 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.50501023 |
104 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.49995918 |
105 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 0.47176408 |
106 | Carbon metabolism_Homo sapiens_hsa01200 | 0.47104081 |
107 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.45838904 |
108 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.45693279 |
109 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.44344919 |
110 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 0.43082156 |
111 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.42997220 |
112 | Lysine degradation_Homo sapiens_hsa00310 | 0.42843088 |
113 | Tuberculosis_Homo sapiens_hsa05152 | 0.41727744 |
114 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.40365113 |
115 | Hepatitis C_Homo sapiens_hsa05160 | 0.40341827 |
116 | Pathways in cancer_Homo sapiens_hsa05200 | 0.40010232 |
117 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.39832525 |
118 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.39223744 |
119 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.38949960 |
120 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 0.38124336 |
121 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.37785605 |
122 | Endometrial cancer_Homo sapiens_hsa05213 | 0.37680266 |
123 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.37395068 |
124 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.36131508 |
125 | Other glycan degradation_Homo sapiens_hsa00511 | 0.35782799 |
126 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.34788622 |
127 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.34464393 |
128 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.33914211 |
129 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.29462165 |
130 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.29412361 |
131 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.28632895 |
132 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.28587717 |
133 | Pertussis_Homo sapiens_hsa05133 | 0.27496210 |
134 | Phagosome_Homo sapiens_hsa04145 | 0.26802753 |