

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 8.00465425 |
| 2 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 6.72336718 |
| 3 | ATP synthesis coupled proton transport (GO:0015986) | 6.72336718 |
| 4 | negative regulation of heart rate (GO:0010459) | 6.66649726 |
| 5 | membrane repolarization during cardiac muscle cell action potential (GO:0086013) | 6.58489948 |
| 6 | regulation of hypersensitivity (GO:0002883) | 6.52379358 |
| 7 | neuronal action potential propagation (GO:0019227) | 6.40168661 |
| 8 | positive regulation of protein homodimerization activity (GO:0090073) | 6.13796143 |
| 9 | potassium ion export (GO:0071435) | 6.09330619 |
| 10 | membrane repolarization during action potential (GO:0086011) | 5.79614089 |
| 11 | platelet dense granule organization (GO:0060155) | 5.70251184 |
| 12 | positive regulation of mast cell activation involved in immune response (GO:0033008) | 5.44230747 |
| 13 | positive regulation of mast cell degranulation (GO:0043306) | 5.44230747 |
| 14 | positive regulation of inflammatory response to antigenic stimulus (GO:0002863) | 5.38629098 |
| 15 | negative regulation of calcium ion transport into cytosol (GO:0010523) | 5.33577883 |
| 16 | preassembly of GPI anchor in ER membrane (GO:0016254) | 5.07235789 |
| 17 | positive regulation of granulocyte macrophage colony-stimulating factor production (GO:0032725) | 5.01248068 |
| 18 | hepatocyte differentiation (GO:0070365) | 4.77196510 |
| 19 | response to vitamin E (GO:0033197) | 4.75111122 |
| 20 | spermatid nucleus differentiation (GO:0007289) | 4.70288779 |
| 21 | pyrimidine nucleobase catabolic process (GO:0006208) | 4.70042867 |
| 22 | regulation of acute inflammatory response to antigenic stimulus (GO:0002864) | 4.59201913 |
| 23 | regulation of granulocyte macrophage colony-stimulating factor production (GO:0032645) | 4.55582965 |
| 24 | positive regulation of leukocyte degranulation (GO:0043302) | 4.49928226 |
| 25 | negative regulation of phosphoprotein phosphatase activity (GO:0032515) | 4.45542854 |
| 26 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 4.40352475 |
| 27 | positive regulation of mast cell activation (GO:0033005) | 4.38389795 |
| 28 | protein maturation by protein folding (GO:0022417) | 4.37007161 |
| 29 | acrosome assembly (GO:0001675) | 4.20392525 |
| 30 | membrane repolarization (GO:0086009) | 4.17402317 |
| 31 | positive regulation of potassium ion transmembrane transport (GO:1901381) | 4.08932990 |
| 32 | nucleobase catabolic process (GO:0046113) | 4.06630080 |
| 33 | dopamine transport (GO:0015872) | 4.06331921 |
| 34 | regulation of ventricular cardiac muscle cell membrane repolarization (GO:0060307) | 4.05666953 |
| 35 | monoamine transport (GO:0015844) | 3.97447419 |
| 36 | sarcoplasmic reticulum calcium ion transport (GO:0070296) | 3.95397182 |
| 37 | negative regulation of ryanodine-sensitive calcium-release channel activity (GO:0060315) | 3.93315830 |
| 38 | negative regulation of mast cell activation (GO:0033004) | 3.92147977 |
| 39 | neurotransmitter uptake (GO:0001504) | 3.91408637 |
| 40 | ATP biosynthetic process (GO:0006754) | 3.90534091 |
| 41 | behavioral response to nicotine (GO:0035095) | 3.90248754 |
| 42 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 3.87370648 |
| 43 | respiratory electron transport chain (GO:0022904) | 3.86211522 |
| 44 | electron transport chain (GO:0022900) | 3.82946430 |
| 45 | protein refolding (GO:0042026) | 3.77468822 |
| 46 | synaptic transmission, cholinergic (GO:0007271) | 3.75079689 |
| 47 | postsynaptic membrane organization (GO:0001941) | 3.74840894 |
| 48 | positive regulation of myeloid leukocyte mediated immunity (GO:0002888) | 3.63115244 |
| 49 | positive regulation of cellular response to oxidative stress (GO:1900409) | 3.57500627 |
| 50 | positive regulation of response to oxidative stress (GO:1902884) | 3.57500627 |
| 51 | mitochondrial genome maintenance (GO:0000002) | 3.53411069 |
| 52 | GPI anchor biosynthetic process (GO:0006506) | 3.52427000 |
| 53 | regulation of neuron projection regeneration (GO:0070570) | 3.47253598 |
| 54 | regulation of axon regeneration (GO:0048679) | 3.47253598 |
| 55 | axonemal dynein complex assembly (GO:0070286) | 3.43826016 |
| 56 | kynurenine metabolic process (GO:0070189) | 3.41769590 |
| 57 | positive regulation of T cell cytokine production (GO:0002726) | 3.41595183 |
| 58 | forebrain neuron differentiation (GO:0021879) | 3.39764522 |
| 59 | calcium-mediated signaling using intracellular calcium source (GO:0035584) | 3.38263106 |
| 60 | positive regulation of regulated secretory pathway (GO:1903307) | 3.36022584 |
| 61 | centriole replication (GO:0007099) | 3.31677173 |
| 62 | cell communication by electrical coupling involved in cardiac conduction (GO:0086064) | 3.31225491 |
| 63 | sequestering of actin monomers (GO:0042989) | 3.31021224 |
| 64 | interkinetic nuclear migration (GO:0022027) | 3.24506149 |
| 65 | GPI anchor metabolic process (GO:0006505) | 3.22691978 |
| 66 | regulation of oxidative stress-induced neuron death (GO:1903203) | 3.18329770 |
| 67 | protein localization to cilium (GO:0061512) | 3.18087453 |
| 68 | positive regulation of vesicle fusion (GO:0031340) | 3.17679229 |
| 69 | lactate metabolic process (GO:0006089) | 3.15040299 |
| 70 | chaperone-mediated protein transport (GO:0072321) | 3.14495322 |
| 71 | DNA double-strand break processing (GO:0000729) | 3.14119381 |
| 72 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.05716548 |
| 73 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 3.02569340 |
| 74 | response to redox state (GO:0051775) | 3.00934203 |
| 75 | protein peptidyl-prolyl isomerization (GO:0000413) | 3.00714597 |
| 76 | protein polyglutamylation (GO:0018095) | 2.94481180 |
| 77 | regulation of membrane repolarization (GO:0060306) | 2.94421870 |
| 78 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 2.92741837 |
| 79 | cell communication by electrical coupling (GO:0010644) | 2.90131966 |
| 80 | microtubule anchoring (GO:0034453) | 2.90031559 |
| 81 | epithelial cilium movement (GO:0003351) | 2.89555760 |
| 82 | response to lipoprotein particle (GO:0055094) | 2.89347412 |
| 83 | regulation of mast cell activation (GO:0033003) | 2.87491174 |
| 84 | protein localization to synapse (GO:0035418) | 2.84348877 |
| 85 | forebrain morphogenesis (GO:0048853) | 2.83348398 |
| 86 | cell morphogenesis involved in neuron differentiation (GO:0048667) | 2.83133856 |
| 87 | galactose catabolic process (GO:0019388) | 2.81279000 |
| 88 | negative regulation of cation channel activity (GO:2001258) | 2.79879971 |
| 89 | regulation of autophagic vacuole assembly (GO:2000785) | 2.78341024 |
| 90 | axoneme assembly (GO:0035082) | 2.75653465 |
| 91 | positive regulation of transcription regulatory region DNA binding (GO:2000679) | 2.74692263 |
| 92 | endocrine hormone secretion (GO:0060986) | 2.70247050 |
| 93 | hydrogen ion transmembrane transport (GO:1902600) | 2.69240137 |
| 94 | negative regulation of axon extension involved in axon guidance (GO:0048843) | 2.67637797 |
| 95 | aldehyde catabolic process (GO:0046185) | 2.66888779 |
| 96 | negative regulation of calcium ion transmembrane transporter activity (GO:1901020) | 2.65797118 |
| 97 | negative regulation of calcium ion transmembrane transport (GO:1903170) | 2.65797118 |
| 98 | positive regulation of steroid hormone secretion (GO:2000833) | 2.65764778 |
| 99 | prenylation (GO:0097354) | 2.62050527 |
| 100 | protein prenylation (GO:0018342) | 2.62050527 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TAF15_26573619_Chip-Seq_HEK293_Human | 4.57504597 |
| 2 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 3.72879244 |
| 3 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 3.34142125 |
| 4 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 3.17703612 |
| 5 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.81081285 |
| 6 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 2.76636829 |
| 7 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 2.59009580 |
| 8 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.52882630 |
| 9 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.43367224 |
| 10 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 2.37753466 |
| 11 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 2.30162495 |
| 12 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 2.19558343 |
| 13 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.15008259 |
| 14 | P300_19829295_ChIP-Seq_ESCs_Human | 2.08996338 |
| 15 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 2.07511948 |
| 16 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.01320502 |
| 17 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.96886630 |
| 18 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.96508328 |
| 19 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.95373153 |
| 20 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.91149383 |
| 21 | EWS_26573619_Chip-Seq_HEK293_Human | 1.90174047 |
| 22 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.89831736 |
| 23 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.88266175 |
| 24 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 1.81918551 |
| 25 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.77946520 |
| 26 | EZH2_22144423_ChIP-Seq_EOC_Human | 1.77422582 |
| 27 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 1.76891683 |
| 28 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.75317856 |
| 29 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 1.73029032 |
| 30 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.68228360 |
| 31 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.61560856 |
| 32 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.61061214 |
| 33 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.56080691 |
| 34 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.52170353 |
| 35 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.50975846 |
| 36 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.50666929 |
| 37 | RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse | 1.48449214 |
| 38 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 1.46770430 |
| 39 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.46301703 |
| 40 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.44835984 |
| 41 | HTT_18923047_ChIP-ChIP_STHdh_Human | 1.44546974 |
| 42 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 1.42293447 |
| 43 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 1.37569110 |
| 44 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.36157911 |
| 45 | ERG_20517297_ChIP-Seq_VCAP_Human | 1.33571230 |
| 46 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 1.32494638 |
| 47 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 1.32203308 |
| 48 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.30208360 |
| 49 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.28486004 |
| 50 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.28486004 |
| 51 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.28226877 |
| 52 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.27320602 |
| 53 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.27320602 |
| 54 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.26683681 |
| 55 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 1.26093749 |
| 56 | VDR_22108803_ChIP-Seq_LS180_Human | 1.22510555 |
| 57 | AR_25329375_ChIP-Seq_VCAP_Human | 1.20353372 |
| 58 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.18684097 |
| 59 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 1.18361026 |
| 60 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 1.16498360 |
| 61 | SOX9_26525672_Chip-Seq_Limbbuds_Mouse | 1.14552786 |
| 62 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 1.14133566 |
| 63 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 1.13846903 |
| 64 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.12085953 |
| 65 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.12085953 |
| 66 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 1.11931779 |
| 67 | FUS_26573619_Chip-Seq_HEK293_Human | 1.11795666 |
| 68 | NCOR_22424771_ChIP-Seq_293T_Human | 1.11233403 |
| 69 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.10868254 |
| 70 | P300_18555785_Chip-Seq_ESCs_Mouse | 1.09813993 |
| 71 | NANOG_16153702_ChIP-ChIP_HESCs_Human | 1.09539523 |
| 72 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.07827363 |
| 73 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 1.06763217 |
| 74 | NANOG_18700969_ChIP-ChIP_MESCs_Mouse | 1.06369860 |
| 75 | KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse | 1.05835200 |
| 76 | EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse | 1.05611152 |
| 77 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.04563059 |
| 78 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 1.04519285 |
| 79 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 1.04063617 |
| 80 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.03259731 |
| 81 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.02641168 |
| 82 | P53_22387025_ChIP-Seq_ESCs_Mouse | 1.02407158 |
| 83 | GATA6_21074721_ChIP-Seq_CACO-2_Mouse | 1.02377116 |
| 84 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.02366524 |
| 85 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.01635625 |
| 86 | CMYC_18555785_Chip-Seq_ESCs_Mouse | 1.00334736 |
| 87 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 1.00169338 |
| 88 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 0.99938226 |
| 89 | RBPJ_21746931_ChIP-Seq_IB4_Human | 0.98144241 |
| 90 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 0.98110725 |
| 91 | KAP1_22055183_ChIP-Seq_ESCs_Mouse | 0.97444631 |
| 92 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 0.97277864 |
| 93 | SOX2_18555785_Chip-Seq_ESCs_Mouse | 0.96138709 |
| 94 | TP53_22573176_ChIP-Seq_HFKS_Human | 0.95651195 |
| 95 | AR_20517297_ChIP-Seq_VCAP_Human | 0.95629316 |
| 96 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 0.95344440 |
| 97 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 0.95328002 |
| 98 | ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 0.95321816 |
| 99 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 0.94721657 |
| 100 | REST_21632747_ChIP-Seq_MESCs_Mouse | 0.93720287 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003878_abnormal_ear_physiology | 6.15162938 |
| 2 | MP0005377_hearing/vestibular/ear_phenot | 6.15162938 |
| 3 | MP0002102_abnormal_ear_morphology | 3.79043674 |
| 4 | MP0001485_abnormal_pinna_reflex | 3.10211019 |
| 5 | MP0005084_abnormal_gallbladder_morpholo | 3.02657667 |
| 6 | MP0006292_abnormal_olfactory_placode | 2.83481380 |
| 7 | MP0003787_abnormal_imprinting | 2.55180884 |
| 8 | MP0003122_maternal_imprinting | 2.52935876 |
| 9 | MP0006276_abnormal_autonomic_nervous | 2.46239151 |
| 10 | MP0004147_increased_porphyrin_level | 2.43363747 |
| 11 | MP0003136_yellow_coat_color | 2.41471485 |
| 12 | MP0008961_abnormal_basal_metabolism | 2.24919949 |
| 13 | MP0001919_abnormal_reproductive_system | 2.24476228 |
| 14 | MP0009046_muscle_twitch | 2.12890688 |
| 15 | MP0003137_abnormal_impulse_conducting | 2.02194914 |
| 16 | MP0005187_abnormal_penis_morphology | 1.95013667 |
| 17 | MP0005423_abnormal_somatic_nervous | 1.83411783 |
| 18 | MP0008995_early_reproductive_senescence | 1.80501800 |
| 19 | MP0003724_increased_susceptibility_to | 1.80025136 |
| 20 | MP0003880_abnormal_central_pattern | 1.78593560 |
| 21 | MP0003121_genomic_imprinting | 1.76284713 |
| 22 | MP0005645_abnormal_hypothalamus_physiol | 1.74806031 |
| 23 | MP0008872_abnormal_physiological_respon | 1.67443179 |
| 24 | MP0006072_abnormal_retinal_apoptosis | 1.66632858 |
| 25 | MP0004142_abnormal_muscle_tone | 1.65517338 |
| 26 | MP0000778_abnormal_nervous_system | 1.62634226 |
| 27 | MP0000631_abnormal_neuroendocrine_gland | 1.54261439 |
| 28 | MP0002751_abnormal_autonomic_nervous | 1.51046324 |
| 29 | MP0002735_abnormal_chemical_nociception | 1.46659957 |
| 30 | MP0002928_abnormal_bile_duct | 1.43142671 |
| 31 | MP0001286_abnormal_eye_development | 1.41984351 |
| 32 | MP0000372_irregular_coat_pigmentation | 1.38289287 |
| 33 | MP0000026_abnormal_inner_ear | 1.35104373 |
| 34 | MP0002067_abnormal_sensory_capabilities | 1.33229418 |
| 35 | MP0005367_renal/urinary_system_phenotyp | 1.33032421 |
| 36 | MP0000516_abnormal_urinary_system | 1.33032421 |
| 37 | MP0005389_reproductive_system_phenotype | 1.31803336 |
| 38 | MP0008877_abnormal_DNA_methylation | 1.30267035 |
| 39 | MP0003221_abnormal_cardiomyocyte_apopto | 1.27192237 |
| 40 | MP0000647_abnormal_sebaceous_gland | 1.24177429 |
| 41 | MP0005253_abnormal_eye_physiology | 1.24166632 |
| 42 | MP0009745_abnormal_behavioral_response | 1.20626145 |
| 43 | MP0004215_abnormal_myocardial_fiber | 1.20046694 |
| 44 | MP0002160_abnormal_reproductive_system | 1.18210010 |
| 45 | MP0001486_abnormal_startle_reflex | 1.17915281 |
| 46 | MP0003879_abnormal_hair_cell | 1.15431692 |
| 47 | MP0003786_premature_aging | 1.15201855 |
| 48 | MP0003195_calcinosis | 1.15002016 |
| 49 | MP0001963_abnormal_hearing_physiology | 1.09949390 |
| 50 | MP0001661_extended_life_span | 1.06506253 |
| 51 | MP0003635_abnormal_synaptic_transmissio | 1.05515122 |
| 52 | MP0002557_abnormal_social/conspecific_i | 1.05478096 |
| 53 | MP0002064_seizures | 1.05147562 |
| 54 | MP0004270_analgesia | 1.04762899 |
| 55 | MP0006054_spinal_hemorrhage | 1.02038808 |
| 56 | MP0002184_abnormal_innervation | 0.99297284 |
| 57 | MP0001905_abnormal_dopamine_level | 0.96570164 |
| 58 | MP0009333_abnormal_splenocyte_physiolog | 0.92876834 |
| 59 | MP0002752_abnormal_somatic_nervous | 0.92428271 |
| 60 | MP0001765_abnormal_ion_homeostasis | 0.89851973 |
| 61 | MP0002272_abnormal_nervous_system | 0.88432804 |
| 62 | MP0002277_abnormal_respiratory_mucosa | 0.88087973 |
| 63 | MP0001835_abnormal_antigen_presentation | 0.87531113 |
| 64 | MP0002229_neurodegeneration | 0.84088036 |
| 65 | MP0002882_abnormal_neuron_morphology | 0.83955998 |
| 66 | MP0008775_abnormal_heart_ventricle | 0.83338690 |
| 67 | MP0000579_abnormal_nail_morphology | 0.83257127 |
| 68 | MP0002822_catalepsy | 0.83055762 |
| 69 | MP0001800_abnormal_humoral_immune | 0.82238581 |
| 70 | MP0005386_behavior/neurological_phenoty | 0.79271270 |
| 71 | MP0004924_abnormal_behavior | 0.79271270 |
| 72 | MP0002063_abnormal_learning/memory/cond | 0.78830616 |
| 73 | MP0002638_abnormal_pupillary_reflex | 0.77618468 |
| 74 | MP0000343_altered_response_to | 0.77455829 |
| 75 | MP0005195_abnormal_posterior_eye | 0.76165329 |
| 76 | MP0003633_abnormal_nervous_system | 0.75304692 |
| 77 | MP0002572_abnormal_emotion/affect_behav | 0.75023737 |
| 78 | MP0005636_abnormal_mineral_homeostasis | 0.75022851 |
| 79 | MP0001293_anophthalmia | 0.72774618 |
| 80 | MP0001502_abnormal_circadian_rhythm | 0.72716271 |
| 81 | MP0005391_vision/eye_phenotype | 0.69980290 |
| 82 | MP0001970_abnormal_pain_threshold | 0.69760259 |
| 83 | MP0001663_abnormal_digestive_system | 0.66317027 |
| 84 | MP0006035_abnormal_mitochondrial_morpho | 0.64833488 |
| 85 | MP0000955_abnormal_spinal_cord | 0.64797452 |
| 86 | MP0000685_abnormal_immune_system | 0.64169496 |
| 87 | MP0004043_abnormal_pH_regulation | 0.63289714 |
| 88 | MP0003329_amyloid_beta_deposits | 0.62624004 |
| 89 | MP0004085_abnormal_heartbeat | 0.62440400 |
| 90 | MP0002069_abnormal_eating/drinking_beha | 0.61933289 |
| 91 | MP0004742_abnormal_vestibular_system | 0.61495307 |
| 92 | MP0002972_abnormal_cardiac_muscle | 0.61261204 |
| 93 | MP0004484_altered_response_of | 0.60404850 |
| 94 | MP0010307_abnormal_tumor_latency | 0.60281429 |
| 95 | MP0004811_abnormal_neuron_physiology | 0.60254796 |
| 96 | MP0002234_abnormal_pharynx_morphology | 0.58332806 |
| 97 | MP0005551_abnormal_eye_electrophysiolog | 0.56553179 |
| 98 | MP0002152_abnormal_brain_morphology | 0.55787176 |
| 99 | MP0005499_abnormal_olfactory_system | 0.55667919 |
| 100 | MP0005394_taste/olfaction_phenotype | 0.55667919 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Degeneration of the lateral corticospinal tracts (HP:0002314) | 6.32553296 |
| 2 | Atrophy/Degeneration involving the corticospinal tracts (HP:0007372) | 6.32553296 |
| 3 | Abnormality of the corticospinal tract (HP:0002492) | 5.35281271 |
| 4 | Large eyes (HP:0001090) | 5.14593616 |
| 5 | Lipid accumulation in hepatocytes (HP:0006561) | 4.80200049 |
| 6 | Insidious onset (HP:0003587) | 4.77925958 |
| 7 | Termporal pattern (HP:0011008) | 4.77925958 |
| 8 | Increased hepatocellular lipid droplets (HP:0006565) | 4.73706427 |
| 9 | Chronic sinusitis (HP:0011109) | 4.43404626 |
| 10 | Urinary bladder sphincter dysfunction (HP:0002839) | 3.91033594 |
| 11 | Azoospermia (HP:0000027) | 3.80287527 |
| 12 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 3.68415631 |
| 13 | Absent/shortened dynein arms (HP:0200106) | 3.68415631 |
| 14 | Ventricular fibrillation (HP:0001663) | 3.63794863 |
| 15 | Abnormal ciliary motility (HP:0012262) | 3.56518278 |
| 16 | Impaired vibration sensation in the lower limbs (HP:0002166) | 3.52042154 |
| 17 | Methylmalonic acidemia (HP:0002912) | 3.46421069 |
| 18 | Renal Fanconi syndrome (HP:0001994) | 3.29557571 |
| 19 | Arthropathy (HP:0003040) | 3.21346354 |
| 20 | Exertional dyspnea (HP:0002875) | 3.19561113 |
| 21 | Abnormal respiratory motile cilium morphology (HP:0005938) | 3.16556060 |
| 22 | Abnormal respiratory epithelium morphology (HP:0012253) | 3.16556060 |
| 23 | Abnormal respiratory motile cilium physiology (HP:0012261) | 3.09160679 |
| 24 | Morphological abnormality of the pyramidal tract (HP:0002062) | 3.07453725 |
| 25 | Supernumerary spleens (HP:0009799) | 3.07258945 |
| 26 | Increased intramyocellular lipid droplets (HP:0012240) | 2.99617945 |
| 27 | Urinary urgency (HP:0000012) | 2.92042621 |
| 28 | Type II lissencephaly (HP:0007260) | 2.90206021 |
| 29 | Increased muscle lipid content (HP:0009058) | 2.80949971 |
| 30 | Increased CSF lactate (HP:0002490) | 2.75791206 |
| 31 | Hyperphosphaturia (HP:0003109) | 2.70267752 |
| 32 | Birth length less than 3rd percentile (HP:0003561) | 2.68945061 |
| 33 | Congenital, generalized hypertrichosis (HP:0004540) | 2.65829558 |
| 34 | Prolonged QT interval (HP:0001657) | 2.59087020 |
| 35 | Anteriorly placed anus (HP:0001545) | 2.56458217 |
| 36 | Mitochondrial inheritance (HP:0001427) | 2.53739602 |
| 37 | Abnormal spermatogenesis (HP:0008669) | 2.51627499 |
| 38 | Brittle hair (HP:0002299) | 2.50414192 |
| 39 | Septo-optic dysplasia (HP:0100842) | 2.45770535 |
| 40 | Syncope (HP:0001279) | 2.43432103 |
| 41 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.38506447 |
| 42 | Medulloblastoma (HP:0002885) | 2.36722612 |
| 43 | Hypomagnesemia (HP:0002917) | 2.34156737 |
| 44 | Volvulus (HP:0002580) | 2.33449712 |
| 45 | Abnormality of urine glucose concentration (HP:0011016) | 2.25378986 |
| 46 | Glycosuria (HP:0003076) | 2.25378986 |
| 47 | Renal tubular dysfunction (HP:0000124) | 2.24735914 |
| 48 | Optic nerve hypoplasia (HP:0000609) | 2.24352325 |
| 49 | Decreased subcutaneous fat (HP:0001002) | 2.19786360 |
| 50 | Intestinal atresia (HP:0011100) | 2.17822317 |
| 51 | Methylmalonic aciduria (HP:0012120) | 2.16836629 |
| 52 | Long nose (HP:0003189) | 2.15856229 |
| 53 | Tented upper lip vermilion (HP:0010804) | 2.15575035 |
| 54 | Hemivertebrae (HP:0002937) | 2.13752321 |
| 55 | Polyphagia (HP:0002591) | 2.13229594 |
| 56 | Respiratory difficulties (HP:0002880) | 2.12957699 |
| 57 | Breast hypoplasia (HP:0003187) | 2.12681890 |
| 58 | Acute necrotizing encephalopathy (HP:0006965) | 2.12226981 |
| 59 | Abnormal urine phosphate concentration (HP:0012599) | 2.09196193 |
| 60 | Aplasia/Hypoplasia of the optic nerve (HP:0008058) | 2.08515691 |
| 61 | Bilateral microphthalmos (HP:0007633) | 2.08184975 |
| 62 | Lissencephaly (HP:0001339) | 2.07894375 |
| 63 | Cerebellar dysplasia (HP:0007033) | 2.06801708 |
| 64 | Congenital nonbullous ichthyosiform erythroderma (HP:0007479) | 2.05369668 |
| 65 | Autoamputation (HP:0001218) | 2.04536329 |
| 66 | B lymphocytopenia (HP:0010976) | 2.03220295 |
| 67 | Abnormality of magnesium homeostasis (HP:0004921) | 2.02386010 |
| 68 | Fragile nails (HP:0001808) | 1.99369019 |
| 69 | Mutism (HP:0002300) | 1.98968063 |
| 70 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 1.98032167 |
| 71 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 1.98032167 |
| 72 | Double outlet right ventricle (HP:0001719) | 1.97558968 |
| 73 | Congenital malformation of the right heart (HP:0011723) | 1.97558968 |
| 74 | True hermaphroditism (HP:0010459) | 1.96241984 |
| 75 | Impaired vibratory sensation (HP:0002495) | 1.95348823 |
| 76 | Abnormality of renal resorption (HP:0011038) | 1.94464079 |
| 77 | Abnormality of the vitamin B12 metabolism (HP:0004341) | 1.93746816 |
| 78 | Aplasia/Hypoplasia of the brainstem (HP:0007362) | 1.90738656 |
| 79 | Hypoplasia of the brainstem (HP:0002365) | 1.90738656 |
| 80 | Abnormality of homocysteine metabolism (HP:0010919) | 1.86862261 |
| 81 | Homocystinuria (HP:0002156) | 1.86862261 |
| 82 | Genetic anticipation (HP:0003743) | 1.85264854 |
| 83 | 3-Methylglutaconic aciduria (HP:0003535) | 1.84746566 |
| 84 | Large for gestational age (HP:0001520) | 1.82117935 |
| 85 | Tetany (HP:0001281) | 1.81364705 |
| 86 | Delayed closure of the anterior fontanelle (HP:0001476) | 1.80371965 |
| 87 | Tubular atrophy (HP:0000092) | 1.80328224 |
| 88 | Oligodactyly (hands) (HP:0001180) | 1.80301265 |
| 89 | Muscle hypertrophy of the lower extremities (HP:0008968) | 1.80097506 |
| 90 | Abnormality of vitamin B metabolism (HP:0004340) | 1.79883076 |
| 91 | Abnormal mitochondria in muscle tissue (HP:0008316) | 1.79778124 |
| 92 | Progressive macrocephaly (HP:0004481) | 1.78774996 |
| 93 | Testicular atrophy (HP:0000029) | 1.76766953 |
| 94 | Limb dystonia (HP:0002451) | 1.75523100 |
| 95 | Lower limb muscle weakness (HP:0007340) | 1.74876400 |
| 96 | Pachygyria (HP:0001302) | 1.74075885 |
| 97 | Absent speech (HP:0001344) | 1.73997362 |
| 98 | Calf muscle hypertrophy (HP:0008981) | 1.73035029 |
| 99 | Partial agenesis of the corpus callosum (HP:0001338) | 1.72687049 |
| 100 | Abnormality of B cell number (HP:0010975) | 1.72165177 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MAP3K12 | 4.74284448 |
| 2 | SCYL2 | 4.30360339 |
| 3 | TLK1 | 3.48358089 |
| 4 | ERBB3 | 3.45496287 |
| 5 | BMPR2 | 3.32791030 |
| 6 | NEK2 | 3.16937026 |
| 7 | ZAK | 2.52672096 |
| 8 | CASK | 2.51870628 |
| 9 | TRPM7 | 2.28637567 |
| 10 | MAP4K2 | 2.20464404 |
| 11 | MAP3K4 | 2.20012793 |
| 12 | GRK1 | 2.06601531 |
| 13 | NTRK1 | 1.77075794 |
| 14 | CDK19 | 1.65009726 |
| 15 | ADRBK2 | 1.63535454 |
| 16 | MARK1 | 1.62468883 |
| 17 | TNIK | 1.52930923 |
| 18 | TYRO3 | 1.51641541 |
| 19 | MAP2K7 | 1.48405569 |
| 20 | FES | 1.48245977 |
| 21 | MAP3K6 | 1.47446286 |
| 22 | MAPK15 | 1.40989368 |
| 23 | BUB1 | 1.39094702 |
| 24 | NLK | 1.38287052 |
| 25 | PLK2 | 1.33256392 |
| 26 | CAMKK2 | 1.28297781 |
| 27 | VRK1 | 1.27333709 |
| 28 | MYLK | 1.23988364 |
| 29 | WEE1 | 1.23179154 |
| 30 | PLK4 | 1.13037813 |
| 31 | MINK1 | 1.10742565 |
| 32 | EPHA3 | 1.07806908 |
| 33 | NEK1 | 1.06693844 |
| 34 | ILK | 1.06373542 |
| 35 | NUAK1 | 1.05515258 |
| 36 | PHKG2 | 1.04351379 |
| 37 | PHKG1 | 1.04351379 |
| 38 | BCR | 1.01263288 |
| 39 | PLK3 | 0.98620116 |
| 40 | PNCK | 0.97294712 |
| 41 | PINK1 | 0.96589421 |
| 42 | AURKB | 0.95433545 |
| 43 | FER | 0.94122836 |
| 44 | ALK | 0.91799707 |
| 45 | MAP2K4 | 0.90709808 |
| 46 | NTRK2 | 0.87242433 |
| 47 | EIF2AK2 | 0.86271920 |
| 48 | CCNB1 | 0.84756098 |
| 49 | MAPKAPK3 | 0.83753789 |
| 50 | EIF2AK3 | 0.82828406 |
| 51 | DYRK2 | 0.79428106 |
| 52 | DYRK1B | 0.78086086 |
| 53 | BMPR1B | 0.74449488 |
| 54 | GRK6 | 0.74009546 |
| 55 | MAP3K5 | 0.73082731 |
| 56 | WNK1 | 0.71884291 |
| 57 | PRKCG | 0.67635317 |
| 58 | ROCK1 | 0.67250024 |
| 59 | JAK1 | 0.67121280 |
| 60 | PKN1 | 0.66974888 |
| 61 | CSNK1G2 | 0.66396137 |
| 62 | CSNK1A1L | 0.66018448 |
| 63 | WNK4 | 0.62598329 |
| 64 | HCK | 0.61820138 |
| 65 | TAOK3 | 0.61391865 |
| 66 | FRK | 0.59159584 |
| 67 | CSNK1G3 | 0.58506995 |
| 68 | MKNK2 | 0.58240852 |
| 69 | EPHB2 | 0.56412657 |
| 70 | CSNK1G1 | 0.56391786 |
| 71 | WNK3 | 0.56001305 |
| 72 | MAP3K11 | 0.54875961 |
| 73 | DMPK | 0.54103261 |
| 74 | ERBB2 | 0.53186872 |
| 75 | RPS6KA5 | 0.47935595 |
| 76 | MAP2K6 | 0.46891355 |
| 77 | PTK6 | 0.46867225 |
| 78 | TRIM28 | 0.46107687 |
| 79 | STK11 | 0.45649312 |
| 80 | DAPK2 | 0.45567637 |
| 81 | PRKG1 | 0.44295794 |
| 82 | OXSR1 | 0.42248239 |
| 83 | INSRR | 0.41914839 |
| 84 | MATK | 0.41225714 |
| 85 | NEK9 | 0.37868029 |
| 86 | ADRBK1 | 0.37703256 |
| 87 | PTK2B | 0.36606924 |
| 88 | PRKACA | 0.32828332 |
| 89 | CDK14 | 0.32398741 |
| 90 | MAPK12 | 0.32000515 |
| 91 | PRKCQ | 0.30597925 |
| 92 | MARK3 | 0.29633018 |
| 93 | DAPK3 | 0.28839923 |
| 94 | EIF2AK1 | 0.26254363 |
| 95 | ROCK2 | 0.25981128 |
| 96 | EPHB1 | 0.24828601 |
| 97 | PRKACG | 0.24125539 |
| 98 | EPHA4 | 0.23967547 |
| 99 | MAPK13 | 0.23702833 |
| 100 | PRKCA | 0.23449394 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 4.88193971 |
| 2 | Asthma_Homo sapiens_hsa05310 | 4.45455267 |
| 3 | Parkinsons disease_Homo sapiens_hsa05012 | 4.28321964 |
| 4 | Alzheimers disease_Homo sapiens_hsa05010 | 3.24343006 |
| 5 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 2.92156013 |
| 6 | Huntingtons disease_Homo sapiens_hsa05016 | 2.64800020 |
| 7 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 2.59500025 |
| 8 | Proteasome_Homo sapiens_hsa03050 | 2.49748315 |
| 9 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 2.35202202 |
| 10 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 2.19726316 |
| 11 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 2.19514614 |
| 12 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 1.98226168 |
| 13 | Homologous recombination_Homo sapiens_hsa03440 | 1.98191975 |
| 14 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.95375719 |
| 15 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.94945168 |
| 16 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 1.92721031 |
| 17 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.87680565 |
| 18 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.80987294 |
| 19 | Allograft rejection_Homo sapiens_hsa05330 | 1.77906590 |
| 20 | Protein export_Homo sapiens_hsa03060 | 1.76686302 |
| 21 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.58887743 |
| 22 | Alcoholism_Homo sapiens_hsa05034 | 1.46833669 |
| 23 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 1.43671024 |
| 24 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.41092078 |
| 25 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.40506839 |
| 26 | GABAergic synapse_Homo sapiens_hsa04727 | 1.35030849 |
| 27 | Nicotine addiction_Homo sapiens_hsa05033 | 1.34730247 |
| 28 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.34429288 |
| 29 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 1.11447960 |
| 30 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.09649967 |
| 31 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 1.06403781 |
| 32 | Ribosome_Homo sapiens_hsa03010 | 1.04007964 |
| 33 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 1.02910203 |
| 34 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 1.00193096 |
| 35 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.92484847 |
| 36 | Viral myocarditis_Homo sapiens_hsa05416 | 0.91693018 |
| 37 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.90235354 |
| 38 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.88932660 |
| 39 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.88456269 |
| 40 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.86724968 |
| 41 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.84664608 |
| 42 | Morphine addiction_Homo sapiens_hsa05032 | 0.83665738 |
| 43 | RNA polymerase_Homo sapiens_hsa03020 | 0.82835424 |
| 44 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.79413217 |
| 45 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.77110392 |
| 46 | Circadian entrainment_Homo sapiens_hsa04713 | 0.75850358 |
| 47 | Malaria_Homo sapiens_hsa05144 | 0.73522967 |
| 48 | Glutamatergic synapse_Homo sapiens_hsa04724 | 0.70750329 |
| 49 | Amphetamine addiction_Homo sapiens_hsa05031 | 0.70403151 |
| 50 | Leishmaniasis_Homo sapiens_hsa05140 | 0.66837576 |
| 51 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.65319960 |
| 52 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 0.61919848 |
| 53 | Basal transcription factors_Homo sapiens_hsa03022 | 0.61185467 |
| 54 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.60557074 |
| 55 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.59428497 |
| 56 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.58487488 |
| 57 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.57679999 |
| 58 | Tuberculosis_Homo sapiens_hsa05152 | 0.57021609 |
| 59 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.56392021 |
| 60 | Gastric acid secretion_Homo sapiens_hsa04971 | 0.55817740 |
| 61 | Phototransduction_Homo sapiens_hsa04744 | 0.55702836 |
| 62 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.54875035 |
| 63 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.54625706 |
| 64 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.54380637 |
| 65 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.53225593 |
| 66 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.52330853 |
| 67 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.51639757 |
| 68 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.49827002 |
| 69 | Salmonella infection_Homo sapiens_hsa05132 | 0.48752716 |
| 70 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.46147916 |
| 71 | Peroxisome_Homo sapiens_hsa04146 | 0.45430539 |
| 72 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.42090009 |
| 73 | Spliceosome_Homo sapiens_hsa03040 | 0.41591733 |
| 74 | Axon guidance_Homo sapiens_hsa04360 | 0.41277842 |
| 75 | Phagosome_Homo sapiens_hsa04145 | 0.37889065 |
| 76 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 0.36674461 |
| 77 | Salivary secretion_Homo sapiens_hsa04970 | 0.36504498 |
| 78 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.34030807 |
| 79 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.31797426 |
| 80 | Olfactory transduction_Homo sapiens_hsa04740 | 0.31494263 |
| 81 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.31025419 |
| 82 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.29517770 |
| 83 | RNA degradation_Homo sapiens_hsa03018 | 0.29304487 |
| 84 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.28309185 |
| 85 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.28298375 |
| 86 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.28116449 |
| 87 | Insulin secretion_Homo sapiens_hsa04911 | 0.24126344 |
| 88 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.23672666 |
| 89 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.23284932 |
| 90 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.22872464 |
| 91 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.22715295 |
| 92 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.21885274 |
| 93 | Metabolic pathways_Homo sapiens_hsa01100 | 0.20897758 |
| 94 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.20599922 |
| 95 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.19293406 |
| 96 | ABC transporters_Homo sapiens_hsa02010 | 0.18776509 |
| 97 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.18726136 |
| 98 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.18153146 |
| 99 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.17098706 |
| 100 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.13621971 |

