UBN2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1cytoplasmic mRNA processing body assembly (GO:0033962)5.54223020
2histone H3-K4 trimethylation (GO:0080182)5.14526854
3establishment of protein localization to Golgi (GO:0072600)4.61929152
4negative regulation of translation involved in gene silencing by miRNA (GO:0035278)4.52557864
5negative regulation of translation, ncRNA-mediated (GO:0040033)4.52557864
6regulation of translation, ncRNA-mediated (GO:0045974)4.52557864
7protein targeting to Golgi (GO:0000042)4.23544663
8regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060211)4.17242827
9positive regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060213)4.17242827
10positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO3.86567838
11regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO:1900151)3.86567838
12response to pheromone (GO:0019236)3.82870721
13pre-miRNA processing (GO:0031054)3.77633553
14monoubiquitinated protein deubiquitination (GO:0035520)3.73631571
15peptidyl-lysine trimethylation (GO:0018023)3.69582088
16histone H3-K4 methylation (GO:0051568)3.69027514
17mitotic sister chromatid cohesion (GO:0007064)3.41024463
18histone H3-K36 demethylation (GO:0070544)3.33772401
19regulation of mRNA catabolic process (GO:0061013)3.24042468
20positive regulation of mRNA catabolic process (GO:0061014)3.21752949
21protein localization to Golgi apparatus (GO:0034067)3.21112164
22epithelial cilium movement (GO:0003351)3.14806569
23cilium movement (GO:0003341)3.14266176
24nuclear pore complex assembly (GO:0051292)3.14093466
25interkinetic nuclear migration (GO:0022027)3.11692400
26histone lysine methylation (GO:0034968)3.07498230
27regulation of centriole replication (GO:0046599)3.04632974
28eye photoreceptor cell differentiation (GO:0001754)3.04462403
29photoreceptor cell differentiation (GO:0046530)3.04462403
30acrosome reaction (GO:0007340)2.96470629
31startle response (GO:0001964)2.94853040
32photoreceptor cell maintenance (GO:0045494)2.94729637
33histone H3-K9 methylation (GO:0051567)2.92954958
34sperm motility (GO:0030317)2.89472788
35mRNA splice site selection (GO:0006376)2.87054671
36microtubule anchoring (GO:0034453)2.86675443
37positive regulation of mRNA 3-end processing (GO:0031442)2.85575255
38cerebellar Purkinje cell differentiation (GO:0021702)2.82822150
39retina layer formation (GO:0010842)2.82076487
40positive regulation of mRNA processing (GO:0050685)2.81509550
41presynaptic membrane assembly (GO:0097105)2.81454088
42embryonic retina morphogenesis in camera-type eye (GO:0060059)2.80417473
43histone H3-K9 modification (GO:0061647)2.80126196
44eye photoreceptor cell development (GO:0042462)2.79721547
45regulation of mRNA 3-end processing (GO:0031440)2.76596030
46behavioral response to nicotine (GO:0035095)2.75786793
47nuclear pore organization (GO:0006999)2.74009997
48protein polyglutamylation (GO:0018095)2.69945659
49atrial cardiac muscle cell action potential (GO:0086014)2.68677371
50photoreceptor cell development (GO:0042461)2.68111097
51prostate gland growth (GO:0060736)2.66276102
52musculoskeletal movement (GO:0050881)2.64861769
53multicellular organismal movement (GO:0050879)2.64861769
54cilium or flagellum-dependent cell motility (GO:0001539)2.63729119
55motile cilium assembly (GO:0044458)2.63634558
56negative regulation of cytosolic calcium ion concentration (GO:0051481)2.62493596
57axonemal dynein complex assembly (GO:0070286)2.61991272
58snRNA transcription (GO:0009301)2.61588875
59microtubule polymerization or depolymerization (GO:0031109)2.59930999
60peptidyl-lysine methylation (GO:0018022)2.58541662
61regulation of DNA endoreduplication (GO:0032875)2.56695799
62regulation of posttranscriptional gene silencing (GO:0060147)2.54599546
63regulation of gene silencing by miRNA (GO:0060964)2.54599546
64regulation of gene silencing by RNA (GO:0060966)2.54599546
65cerebral cortex radially oriented cell migration (GO:0021799)2.53381897
66axoneme assembly (GO:0035082)2.51578475
67microtubule depolymerization (GO:0007019)2.51074384
68nonmotile primary cilium assembly (GO:0035058)2.49671938
69cAMP catabolic process (GO:0006198)2.49559145
70negative regulation of histone methylation (GO:0031061)2.49086231
71regulation of meiosis I (GO:0060631)2.48205872
72positive regulation of mRNA metabolic process (GO:1903313)2.47301278
73regulation of sarcomere organization (GO:0060297)2.47214744
74appendage development (GO:0048736)2.45700652
75limb development (GO:0060173)2.45700652
76ncRNA catabolic process (GO:0034661)2.45162125
77regulation of protein polyubiquitination (GO:1902914)2.44493450
78histone H3-K9 demethylation (GO:0033169)2.44145095
79peptidyl-threonine dephosphorylation (GO:0035970)2.42963997
80histone lysine demethylation (GO:0070076)2.42917250
81presynaptic membrane organization (GO:0097090)2.42209576
82retinal cone cell development (GO:0046549)2.41754336
83microtubule nucleation (GO:0007020)2.40118545
84embryonic camera-type eye morphogenesis (GO:0048596)2.37645561
85kidney morphogenesis (GO:0060993)2.37176635
86histone mRNA catabolic process (GO:0071044)2.36727711
87intra-Golgi vesicle-mediated transport (GO:0006891)2.35857779
88centriole assembly (GO:0098534)2.35332930
89centriole replication (GO:0007099)2.33545464
90synaptic vesicle endocytosis (GO:0048488)2.33093263
91Golgi to endosome transport (GO:0006895)2.31813136
92establishment of nucleus localization (GO:0040023)2.31490288
93stress granule assembly (GO:0034063)2.30885802
94single strand break repair (GO:0000012)2.30642185
95epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)2.30553060
96neural tube formation (GO:0001841)2.30516066
97replicative senescence (GO:0090399)2.30304386
98histone demethylation (GO:0016577)2.29870702
99spinal cord motor neuron differentiation (GO:0021522)2.29536198
100regulation of gene expression by genetic imprinting (GO:0006349)2.29181820
101protein K11-linked deubiquitination (GO:0035871)2.28594519
102regulation of establishment of cell polarity (GO:2000114)2.27925512
103mesenchymal cell differentiation (GO:0048762)2.27325670
104limb bud formation (GO:0060174)2.26949356
105regulation of inhibitory postsynaptic membrane potential (GO:0060080)2.26870741
106neurological system process involved in regulation of systemic arterial blood pressure (GO:0001976)2.26590228
107histone methylation (GO:0016571)2.26053523
108regulation of pigment cell differentiation (GO:0050932)2.26047138
109ventricular system development (GO:0021591)2.25657749
110cellular component assembly involved in morphogenesis (GO:0010927)2.25581800
111somite rostral/caudal axis specification (GO:0032525)2.25177281
112central nervous system neuron axonogenesis (GO:0021955)2.24919650
113vesicle transport along microtubule (GO:0047496)2.24383205
114microtubule organizing center organization (GO:0031023)2.23235386
115olfactory bulb development (GO:0021772)2.22745905
116calcium ion import (GO:0070509)2.22535941
117regulation of centrosome duplication (GO:0010824)2.21770934
118positive regulation of DNA-dependent DNA replication (GO:2000105)2.21593634
119negative regulation of neurotransmitter transport (GO:0051589)2.21211159
120pore complex assembly (GO:0046931)2.19740007
121regulation of non-canonical Wnt signaling pathway (GO:2000050)2.19607335
122negative regulation of keratinocyte proliferation (GO:0010839)2.18709566
123regulation of establishment or maintenance of cell polarity (GO:0032878)2.18689703
124protein K63-linked deubiquitination (GO:0070536)2.18348984
125dentate gyrus development (GO:0021542)2.18276981
126RNA localization (GO:0006403)2.18126661
127sister chromatid cohesion (GO:0007062)2.17011289
128detection of light stimulus involved in visual perception (GO:0050908)2.16761191
129detection of light stimulus involved in sensory perception (GO:0050962)2.16761191
130head development (GO:0060322)2.16021746
131somite development (GO:0061053)2.15669786
132negative regulation of DNA-dependent DNA replication (GO:2000104)2.10759886
133poly(A)+ mRNA export from nucleus (GO:0016973)2.10544445
134cell morphogenesis involved in neuron differentiation (GO:0048667)2.09632798
135central nervous system projection neuron axonogenesis (GO:0021952)2.09208797
136nucleus localization (GO:0051647)2.08948024
137retrograde transport, vesicle recycling within Golgi (GO:0000301)2.05511470
138negative regulation of osteoblast proliferation (GO:0033689)2.04454918
139reflex (GO:0060004)2.02893560
140cilium assembly (GO:0042384)2.02346015
141regulation of telomere maintenance (GO:0032204)2.01955320
142protein localization to microtubule cytoskeleton (GO:0072698)2.01806201
143cilium organization (GO:0044782)2.01634127
144inner ear receptor cell differentiation (GO:0060113)2.00931525
145cyclic nucleotide catabolic process (GO:0009214)1.99974555
146genitalia morphogenesis (GO:0035112)1.99960502
147cell proliferation in forebrain (GO:0021846)1.99376552
148phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092)1.98802649
149positive regulation of meiosis (GO:0045836)1.98479386
150protein K48-linked deubiquitination (GO:0071108)1.98475124
151regulation of rhodopsin mediated signaling pathway (GO:0022400)1.98447544
152G-protein coupled receptor internalization (GO:0002031)1.98356706
153negative regulation of neurotransmitter secretion (GO:0046929)1.98339896
154lateral sprouting from an epithelium (GO:0060601)1.97363460

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1GBX2_23144817_ChIP-Seq_PC3_Human3.34681455
2CEBPD_23245923_ChIP-Seq_MEFs_Mouse2.55248093
3GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.55111446
4POU3F2_20337985_ChIP-ChIP_501MEL_Human2.37802309
5EZH2_22144423_ChIP-Seq_EOC_Human2.29498371
6ZNF274_21170338_ChIP-Seq_K562_Hela2.26787044
7ZFP57_27257070_Chip-Seq_ESCs_Mouse2.26385609
8VDR_22108803_ChIP-Seq_LS180_Human2.25711210
9SMARCD1_25818293_ChIP-Seq_ESCs_Mouse2.25534540
10ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.14136544
11SALL1_21062744_ChIP-ChIP_HESCs_Human2.12892313
12SMAD_19615063_ChIP-ChIP_OVARY_Human1.94317326
13AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.88866419
14TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.88610277
15PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.85925389
16FLI1_27457419_Chip-Seq_LIVER_Mouse1.85525662
17PCGF2_27294783_Chip-Seq_ESCs_Mouse1.78480990
18FUS_26573619_Chip-Seq_HEK293_Human1.75681064
19NANOG_18555785_Chip-Seq_ESCs_Mouse1.75171371
20GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.73774363
21PIAS1_25552417_ChIP-Seq_VCAP_Human1.71998108
22AR_21572438_ChIP-Seq_LNCaP_Human1.71472571
23P300_19829295_ChIP-Seq_ESCs_Human1.71422030
24BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.71058284
25ZNF217_24962896_ChIP-Seq_MCF-7_Human1.70105201
26SUZ12_27294783_Chip-Seq_NPCs_Mouse1.69912171
27TAF15_26573619_Chip-Seq_HEK293_Human1.69134806
28* SMAD4_21799915_ChIP-Seq_A2780_Human1.68780259
29STAT3_23295773_ChIP-Seq_U87_Human1.68593910
30RBPJ_22232070_ChIP-Seq_NCS_Mouse1.65903121
31IGF1R_20145208_ChIP-Seq_DFB_Human1.63014366
32E2F1_18555785_Chip-Seq_ESCs_Mouse1.61924184
33* UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.61056136
34RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.60634149
35EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.60208671
36NFE2_27457419_Chip-Seq_LIVER_Mouse1.59477132
37MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.59312566
38IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.58722776
39CBP_20019798_ChIP-Seq_JUKART_Human1.58722776
40ARNT_22903824_ChIP-Seq_MCF-7_Human1.58353073
41CDX2_19796622_ChIP-Seq_MESCs_Mouse1.57991520
42EWS_26573619_Chip-Seq_HEK293_Human1.57826337
43TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.57432450
44POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.57432450
45AHR_22903824_ChIP-Seq_MCF-7_Human1.56498108
46ER_23166858_ChIP-Seq_MCF-7_Human1.56446619
47PCGF2_27294783_Chip-Seq_NPCs_Mouse1.55393175
48EZH2_27294783_Chip-Seq_NPCs_Mouse1.52777291
49* TCF4_23295773_ChIP-Seq_U87_Human1.51229031
50CBX2_27304074_Chip-Seq_ESCs_Mouse1.50595767
51TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.49704805
52SUZ12_18555785_Chip-Seq_ESCs_Mouse1.49438111
53SMAD3_21741376_ChIP-Seq_EPCs_Human1.47775435
54FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.47339758
55VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.47066327
56P53_22387025_ChIP-Seq_ESCs_Mouse1.46940841
57CMYC_18555785_Chip-Seq_ESCs_Mouse1.45889617
58* OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.43784807
59FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.43678148
60TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.42379447
61CTBP2_25329375_ChIP-Seq_LNCAP_Human1.39817320
62HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.39759626
63CTBP1_25329375_ChIP-Seq_LNCAP_Human1.37543018
64TP63_19390658_ChIP-ChIP_HaCaT_Human1.37122519
65CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.36411151
66PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.35691059
67P300_18555785_Chip-Seq_ESCs_Mouse1.34589180
68MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.33099224
69EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.32871405
70SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.31537284
71JARID2_20064375_ChIP-Seq_MESCs_Mouse1.31125319
72STAT3_18555785_Chip-Seq_ESCs_Mouse1.30580221
73RNF2_27304074_Chip-Seq_NSC_Mouse1.30214177
74BCAT_22108803_ChIP-Seq_LS180_Human1.29743171
75OCT4_18555785_Chip-Seq_ESCs_Mouse1.28911883
76BMI1_23680149_ChIP-Seq_NPCS_Mouse1.27364275
77TP53_16413492_ChIP-PET_HCT116_Human1.25919534
78SOX2_18555785_Chip-Seq_ESCs_Mouse1.25767383
79NMYC_18555785_Chip-Seq_ESCs_Mouse1.25692327
80HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.24219156
81DROSHA_22980978_ChIP-Seq_HELA_Human1.24053070
82RUNX2_22187159_ChIP-Seq_PCA_Human1.23846802
83FOXM1_26456572_ChIP-Seq_MCF-7_Human1.23510221
84SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.22772453
85REST_21632747_ChIP-Seq_MESCs_Mouse1.21603051
86EZH2_27304074_Chip-Seq_ESCs_Mouse1.21207776
87KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.20995023
88SMAD4_21741376_ChIP-Seq_EPCs_Human1.20697205
89TBL1_22424771_ChIP-Seq_293T_Human1.19232422
90FLI1_21867929_ChIP-Seq_TH2_Mouse1.19135635
91TCF4_22108803_ChIP-Seq_LS180_Human1.18683259
92STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.17959315
93* TOP2B_26459242_ChIP-Seq_MCF-7_Human1.17623028
94YAP1_20516196_ChIP-Seq_MESCs_Mouse1.17201208
95CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.16302282
96KLF5_20875108_ChIP-Seq_MESCs_Mouse1.16022699
97AR_25329375_ChIP-Seq_VCAP_Human1.15975541
98PRDM14_20953172_ChIP-Seq_ESCs_Human1.15644786
99TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.15604242
100TAL1_26923725_Chip-Seq_HPCs_Mouse1.15227412
101RUNX1_27457419_Chip-Seq_LIVER_Mouse1.14657422
102SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.12786679
103RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.12709298
104LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse1.12576456
105CTNNB1_20460455_ChIP-Seq_HCT116_Human1.12535693
106ZFX_18555785_Chip-Seq_ESCs_Mouse1.12344455
107NR3C1_21868756_ChIP-Seq_MCF10A_Human1.11989299
108CTCF_18555785_Chip-Seq_ESCs_Mouse1.11582367
109RNF2_27304074_Chip-Seq_ESCs_Mouse1.11277561
110TCF4_18268006_ChIP-ChIP_LS174T_Human1.11228774
111PU1_27457419_Chip-Seq_LIVER_Mouse1.11024740
112SOX2_21211035_ChIP-Seq_LN229_Gbm1.10269066
113TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.09568995
114SMAD3_21741376_ChIP-Seq_ESCs_Human1.09519448
115* TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.09250404
116LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.08864546
117* CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.08670899
118SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.08623162
119ESRRB_18555785_Chip-Seq_ESCs_Mouse1.08342317
120KLF4_18555785_Chip-Seq_ESCs_Mouse1.08268490
121RXR_22108803_ChIP-Seq_LS180_Human1.07966862
122KDM2B_26808549_Chip-Seq_REH_Human1.06107680
123FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.05826073
124CDX2_22108803_ChIP-Seq_LS180_Human1.01951827
125JUN_21703547_ChIP-Seq_K562_Human1.00336081
126AR_19668381_ChIP-Seq_PC3_Human0.99999548
127SMAD4_21741376_ChIP-Seq_HESCs_Human0.98829893
128FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human0.97172585

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0000569_abnormal_digit_pigmentation3.88411177
2MP0006292_abnormal_olfactory_placode3.60239421
3MP0000566_synostosis3.47021385
4MP0003787_abnormal_imprinting3.28146216
5MP0005409_darkened_coat_color3.16427655
6MP0005551_abnormal_eye_electrophysiolog2.26231588
7MP0001188_hyperpigmentation2.16528319
8MP0002009_preneoplasia2.06707024
9MP0004043_abnormal_pH_regulation2.04630031
10MP0004381_abnormal_hair_follicle2.02152810
11MP0000383_abnormal_hair_follicle2.01714139
12MP0003890_abnormal_embryonic-extraembry1.99346148
13MP0008057_abnormal_DNA_replication1.98596103
14MP0003136_yellow_coat_color1.94459549
15MP0006072_abnormal_retinal_apoptosis1.84298485
16MP0003195_calcinosis1.77064973
17MP0000015_abnormal_ear_pigmentation1.74589457
18MP0003646_muscle_fatigue1.73629954
19MP0001346_abnormal_lacrimal_gland1.73263169
20MP0005248_abnormal_Harderian_gland1.72759251
21MP0005253_abnormal_eye_physiology1.69655538
22MP0008877_abnormal_DNA_methylation1.65480274
23MP0005646_abnormal_pituitary_gland1.63355991
24MP0001486_abnormal_startle_reflex1.62755516
25MP0003121_genomic_imprinting1.60332623
26MP0002638_abnormal_pupillary_reflex1.58468853
27MP0008995_early_reproductive_senescence1.58214044
28MP0005645_abnormal_hypothalamus_physiol1.56533994
29MP0000631_abnormal_neuroendocrine_gland1.54842295
30MP0000778_abnormal_nervous_system1.52593441
31MP0010678_abnormal_skin_adnexa1.52090052
32MP0005410_abnormal_fertilization1.51913338
33MP0001984_abnormal_olfaction1.49140509
34MP0005174_abnormal_tail_pigmentation1.47625495
35MP0004147_increased_porphyrin_level1.45734676
36MP0003950_abnormal_plasma_membrane1.42641532
37MP0005367_renal/urinary_system_phenotyp1.42177389
38MP0000516_abnormal_urinary_system1.42177389
39MP0000427_abnormal_hair_cycle1.41616257
40MP0001502_abnormal_circadian_rhythm1.41383436
41MP0005187_abnormal_penis_morphology1.40285678
42MP0001501_abnormal_sleep_pattern1.38802876
43MP0005171_absent_coat_pigmentation1.38401896
44MP0002735_abnormal_chemical_nociception1.34725619
45MP0002938_white_spotting1.33809316
46MP0002095_abnormal_skin_pigmentation1.30882911
47MP0004145_abnormal_muscle_electrophysio1.29360585
48MP0002272_abnormal_nervous_system1.27456361
49MP0003635_abnormal_synaptic_transmissio1.27197638
50MP0005423_abnormal_somatic_nervous1.26770474
51MP0003941_abnormal_skin_development1.23814727
52MP0009745_abnormal_behavioral_response1.22844123
53MP0001929_abnormal_gametogenesis1.22818908
54MP0002063_abnormal_learning/memory/cond1.21465833
55MP0000955_abnormal_spinal_cord1.20935609
56MP0003045_fibrosis1.19657672
57MP0004742_abnormal_vestibular_system1.19138366
58MP0001299_abnormal_eye_distance/1.17908601
59MP0002734_abnormal_mechanical_nocicepti1.16529120
60MP0005670_abnormal_white_adipose1.15603272
61MP0003183_abnormal_peptide_metabolism1.13708843
62MP0002184_abnormal_innervation1.13478379
63MP0002822_catalepsy1.12089794
64MP0003935_abnormal_craniofacial_develop1.11967800
65MP0003718_maternal_effect1.11834589
66MP0005195_abnormal_posterior_eye1.10075258
67MP0005391_vision/eye_phenotype1.09948106
68MP0003937_abnormal_limbs/digits/tail_de1.08652227
69MP0008961_abnormal_basal_metabolism1.08475787
70MP0004270_analgesia1.07766351
71MP0004885_abnormal_endolymph1.07304073
72MP0001324_abnormal_eye_pigmentation1.07090148
73MP0006276_abnormal_autonomic_nervous1.06876168
74MP0002098_abnormal_vibrissa_morphology1.06490152
75MP0001986_abnormal_taste_sensitivity1.03972170
76MP0002177_abnormal_outer_ear1.03071372
77MP0002102_abnormal_ear_morphology1.02920252
78MP0000647_abnormal_sebaceous_gland1.02915065
79MP0001968_abnormal_touch/_nociception1.02445518
80MP0002928_abnormal_bile_duct1.01351601
81MP0009780_abnormal_chondrocyte_physiolo1.00856180
82MP0005377_hearing/vestibular/ear_phenot1.00734060
83MP0003878_abnormal_ear_physiology1.00734060
84MP0001177_atelectasis1.00695957
85MP0009046_muscle_twitch1.00008638
86MP0000579_abnormal_nail_morphology0.99388704
87MP0004859_abnormal_synaptic_plasticity0.98588274
88MP0000432_abnormal_head_morphology0.97506476
89MP0010386_abnormal_urinary_bladder0.97458432
90MP0002152_abnormal_brain_morphology0.96574012
91MP0003755_abnormal_palate_morphology0.96533132
92MP0000428_abnormal_craniofacial_morphol0.95677027
93MP0003880_abnormal_central_pattern0.95051825
94MP0002557_abnormal_social/conspecific_i0.94880757
95MP0004085_abnormal_heartbeat0.94555308
96MP0002064_seizures0.94281782
97MP0003119_abnormal_digestive_system0.93906348
98MP0001293_anophthalmia0.91881407
99MP0005394_taste/olfaction_phenotype0.91705988
100MP0005499_abnormal_olfactory_system0.91705988
101MP0002210_abnormal_sex_determination0.91513662
102MP0005257_abnormal_intraocular_pressure0.90655403
103MP0004215_abnormal_myocardial_fiber0.90629756
104MP0005379_endocrine/exocrine_gland_phen0.90302533
105MP0004133_heterotaxia0.89760268
106MP0002084_abnormal_developmental_patter0.87956821
107MP0003938_abnormal_ear_development0.87156025
108MP0002075_abnormal_coat/hair_pigmentati0.87106369
109MP0004811_abnormal_neuron_physiology0.86760596
110MP0002116_abnormal_craniofacial_bone0.86540385
111MP0008058_abnormal_DNA_repair0.84972589
112MP0001286_abnormal_eye_development0.84858695
113MP0009703_decreased_birth_body0.83442975
114MP0004134_abnormal_chest_morphology0.83302057
115MP0000462_abnormal_digestive_system0.83217117
116MP0004084_abnormal_cardiac_muscle0.82618967
117MP0000653_abnormal_sex_gland0.82346764
118MP0001485_abnormal_pinna_reflex0.81324044
119MP0002752_abnormal_somatic_nervous0.80339844
120MP0003943_abnormal_hepatobiliary_system0.80110640
121MP0005075_abnormal_melanosome_morpholog0.79776156
122MP0010307_abnormal_tumor_latency0.79667424
123MP0002837_dystrophic_cardiac_calcinosis0.78858204
124MP0003632_abnormal_nervous_system0.78402505
125MP0001186_pigmentation_phenotype0.77998764
126MP0002229_neurodegeneration0.77692550
127MP0002909_abnormal_adrenal_gland0.77121357
128MP0003861_abnormal_nervous_system0.76758722
129MP0003567_abnormal_fetal_cardiomyocyte0.75660602
130MP0001970_abnormal_pain_threshold0.75617523
131MP0002067_abnormal_sensory_capabilities0.75520113
132MP0002572_abnormal_emotion/affect_behav0.75109536
133MP0000026_abnormal_inner_ear0.74720708
134MP0004924_abnormal_behavior0.74599160
135MP0005386_behavior/neurological_phenoty0.74599160
136MP0003656_abnormal_erythrocyte_physiolo0.74550869
137MP0001145_abnormal_male_reproductive0.73938836
138MP0008789_abnormal_olfactory_epithelium0.73807043
139MP0003122_maternal_imprinting0.73316161
140MP0002233_abnormal_nose_morphology0.73285272
141MP0002882_abnormal_neuron_morphology0.73186248
142MP0009697_abnormal_copulation0.73134570
143MP0001851_eye_inflammation0.72835343
144MP0003698_abnormal_male_reproductive0.71884568
145MP0002697_abnormal_eye_size0.70913599
146MP0002109_abnormal_limb_morphology0.70690454
147MP0001879_abnormal_lymphatic_vessel0.69057020
148MP0001963_abnormal_hearing_physiology0.69032107

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of the fingertips (HP:0001211)3.62020757
2Hyperventilation (HP:0002883)3.51016876
3Abnormal hair whorl (HP:0010721)2.90027321
4Progressive cerebellar ataxia (HP:0002073)2.89259121
5Congenital stationary night blindness (HP:0007642)2.83874819
6Abnormality of the renal cortex (HP:0011035)2.77702543
7Abnormality of the nasal septum (HP:0000419)2.76788576
8Respiratory insufficiency due to defective ciliary clearance (HP:0200073)2.74605159
9Volvulus (HP:0002580)2.74562349
10Abnormality of incisor morphology (HP:0011063)2.70120826
11Gaze-evoked nystagmus (HP:0000640)2.64806502
12Midline defect of the nose (HP:0004122)2.63762866
13Lip pit (HP:0100267)2.63134207
14Hepatoblastoma (HP:0002884)2.62997631
15Hyperkalemia (HP:0002153)2.60900022
16Febrile seizures (HP:0002373)2.57121050
17Absent/shortened dynein arms (HP:0200106)2.56648144
18Dynein arm defect of respiratory motile cilia (HP:0012255)2.56648144
19Chromosomal breakage induced by crosslinking agents (HP:0003221)2.51850238
20Chronic hepatic failure (HP:0100626)2.50031672
21Dyschromatopsia (HP:0007641)2.39847105
22Chromsome breakage (HP:0040012)2.37974477
23Birth length less than 3rd percentile (HP:0003561)2.34852001
24Pancreatic fibrosis (HP:0100732)2.33630324
25True hermaphroditism (HP:0010459)2.31369300
26Acute myeloid leukemia (HP:0004808)2.29651586
27Urethral obstruction (HP:0000796)2.24571856
28Widely spaced teeth (HP:0000687)2.21647815
29Aplasia/Hypoplasia of the sternum (HP:0006714)2.21367640
30Abnormality of the parietal bone (HP:0002696)2.20880296
31Anal stenosis (HP:0002025)2.18580009
32Aplasia cutis congenita (HP:0001057)2.17438711
33Abnormality of the columella (HP:0009929)2.16704370
34Abnormal respiratory motile cilium physiology (HP:0012261)2.16460707
35Ectopic kidney (HP:0000086)2.16175003
36Abnormality of the parathyroid morphology (HP:0011766)2.14964868
37Tubular atrophy (HP:0000092)2.13724416
38Abnormal ciliary motility (HP:0012262)2.13076221
39Long nose (HP:0003189)2.11597627
40Narrow palate (HP:0000189)2.10694502
41Poor coordination (HP:0002370)2.09697000
42Astrocytoma (HP:0009592)2.09241839
43Abnormality of the astrocytes (HP:0100707)2.09241839
44Abnormality of the ischium (HP:0003174)2.09205748
45Bony spicule pigmentary retinopathy (HP:0007737)2.09059140
46Protruding tongue (HP:0010808)2.08583902
47Decreased central vision (HP:0007663)2.08297718
48Congenital sensorineural hearing impairment (HP:0008527)2.08081183
49Papillary thyroid carcinoma (HP:0002895)2.07937919
50Abnormal respiratory epithelium morphology (HP:0012253)2.07534187
51Abnormal respiratory motile cilium morphology (HP:0005938)2.07534187
52Long eyelashes (HP:0000527)2.07522331
53Aqueductal stenosis (HP:0002410)2.07207934
54Macroorchidism (HP:0000053)2.04777915
55Abnormal pancreas size (HP:0012094)2.03035703
56Diastasis recti (HP:0001540)2.01779704
57Genital tract atresia (HP:0001827)2.01706859
58Absent eyebrow (HP:0002223)2.01476384
59Abnormality of the renal medulla (HP:0100957)2.00162021
60Aplasia/Hypoplasia of the tongue (HP:0010295)1.99786455
61Abnormality of the labia minora (HP:0012880)1.99515485
62Tubulointerstitial nephritis (HP:0001970)1.99312813
63Glioma (HP:0009733)1.98026902
64Cystic liver disease (HP:0006706)1.96978034
65Nephronophthisis (HP:0000090)1.94659332
66Neoplasm of the adrenal cortex (HP:0100641)1.94564893
67Abnormality of midbrain morphology (HP:0002418)1.93579321
68Molar tooth sign on MRI (HP:0002419)1.93579321
69Tubulointerstitial abnormality (HP:0001969)1.92657584
70Abnormality of the aortic arch (HP:0012303)1.92234350
71Cupped ear (HP:0000378)1.91475900
72Abnormal rod and cone electroretinograms (HP:0008323)1.90138332
73Focal seizures (HP:0007359)1.89538610
74Labial hypoplasia (HP:0000066)1.88667082
75Abnormality of the incisor (HP:0000676)1.88457585
76Attenuation of retinal blood vessels (HP:0007843)1.87982541
77Polydipsia (HP:0001959)1.86515363
78Abnormal drinking behavior (HP:0030082)1.86515363
79Oligodactyly (hands) (HP:0001180)1.85847032
80Fair hair (HP:0002286)1.84494201
81Generalized hypopigmentation of hair (HP:0011358)1.84362286
82Trigonocephaly (HP:0000243)1.84343039
83Exotropia (HP:0000577)1.84040024
84Vaginal atresia (HP:0000148)1.82827278
85Neonatal hypoglycemia (HP:0001998)1.82328230
86Absent rod-and cone-mediated responses on ERG (HP:0007688)1.81916108
87Truncal obesity (HP:0001956)1.81477654
88Hypoplastic labia majora (HP:0000059)1.81477313
89Hypoplastic iliac wings (HP:0002866)1.79301688
90Occipital encephalocele (HP:0002085)1.77729269
91Abnormality of the pubic bones (HP:0003172)1.77596640
92Anteriorly placed anus (HP:0001545)1.77086271
93Partial agenesis of the corpus callosum (HP:0001338)1.76951040
94Absent speech (HP:0001344)1.76132612
95Renal cortical cysts (HP:0000803)1.75597428
96Long clavicles (HP:0000890)1.75323459
97Preaxial hand polydactyly (HP:0001177)1.75186244
98Pancreatic cysts (HP:0001737)1.73831197
99Hypoplasia of the maxilla (HP:0000327)1.73620214
100Rhabdomyosarcoma (HP:0002859)1.73460903
101Absent frontal sinuses (HP:0002688)1.73066112
102Decreased circulating renin level (HP:0003351)1.72963208
103Supernumerary ribs (HP:0005815)1.72565604
104Submucous cleft hard palate (HP:0000176)1.72120071
105Gait imbalance (HP:0002141)1.71613421
106Aplasia/Hypoplasia of the tibia (HP:0005772)1.71590926
107Rhinitis (HP:0012384)1.71073238
108Stomach cancer (HP:0012126)1.71046606
109Neoplasm of the oral cavity (HP:0100649)1.70873147
110Thyroid carcinoma (HP:0002890)1.70122112
111Blue irides (HP:0000635)1.70024556
112Atonic seizures (HP:0010819)1.69508021
113Neoplasm of striated muscle (HP:0009728)1.68891541
114Colon cancer (HP:0003003)1.68430925
115Aplasia/Hypoplasia of the pubic bone (HP:0009104)1.68336086
116Hypoplastic ischia (HP:0003175)1.68078583
117Chorioretinal atrophy (HP:0000533)1.67957447
118Intestinal fistula (HP:0100819)1.67442063
119Small hand (HP:0200055)1.67048429
120Depressed nasal tip (HP:0000437)1.66921682
121Central scotoma (HP:0000603)1.66522255
122Ectropion (HP:0000656)1.66381203
123Dialeptic seizures (HP:0011146)1.65249974
124Sandal gap (HP:0001852)1.64849096
125Genetic anticipation (HP:0003743)1.64695754
126Drooling (HP:0002307)1.64482909
127Excessive salivation (HP:0003781)1.64482909
128Patellar aplasia (HP:0006443)1.64181137
129Bell-shaped thorax (HP:0001591)1.63820510
130Median cleft lip (HP:0000161)1.63195808
131Obsessive-compulsive behavior (HP:0000722)1.63005493
132Prostate neoplasm (HP:0100787)1.62490151
133Decreased lacrimation (HP:0000633)1.62470099
134Abnormality of the labia majora (HP:0012881)1.62167787
135Duplicated collecting system (HP:0000081)1.61708272
136Intestinal atresia (HP:0011100)1.60903054
137Abnormality of the renal collecting system (HP:0004742)1.60570955
138Highly arched eyebrow (HP:0002553)1.60028264
139Epileptic encephalopathy (HP:0200134)1.58331770
140Deep philtrum (HP:0002002)1.56904397
141Septo-optic dysplasia (HP:0100842)1.56645771
142Renal dysplasia (HP:0000110)1.54764089
143Pendular nystagmus (HP:0012043)1.54291240
144Aplasia/Hypoplasia of the fovea (HP:0008060)1.54018941
145Hypoplasia of the fovea (HP:0007750)1.54018941
146Cutaneous finger syndactyly (HP:0010554)1.53360714
147Supernumerary bones of the axial skeleton (HP:0009144)1.53218733
148Abnormality of macular pigmentation (HP:0008002)1.53187227
149Abnormality of the right ventricle (HP:0001707)1.52881142
150Medial flaring of the eyebrow (HP:0010747)1.52579634
151Postaxial foot polydactyly (HP:0001830)1.51741038
152Broad-based gait (HP:0002136)1.50254824
153Hypoplastic nipples (HP:0002557)1.50037951

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MKNK24.19105676
2TNIK3.95737452
3BRD43.23075945
4LATS12.92193472
5MKNK12.72160636
6INSRR2.71653257
7ACVR1B2.61749113
8NUAK12.31584612
9CASK2.31234499
10CDK122.30909550
11CAMK1G2.27117076
12SGK21.86465169
13CAMK1D1.81832925
14PLK41.81568592
15AKT31.74612753
16ZAK1.65847529
17MARK11.62511761
18CDK31.62299351
19YES11.60109384
20STK38L1.59094494
21NEK61.52068208
22TAOK31.47684933
23FRK1.47229327
24SRPK11.44933472
25WNK11.43987345
26BRSK21.42751874
27WNK31.39829009
28SGK31.38344352
29FGFR21.35036982
30NTRK31.33642176
31WNK41.31163305
32PRPF4B1.26035838
33SGK2231.24632949
34SGK4941.24632949
35GRK11.19153919
36MAPK131.12538710
37PIK3CA1.11470500
38BMPR1B1.11139294
39MAP4K21.08989300
40CSNK1A1L1.06869916
41OBSCN1.06808946
42PNCK1.05185329
43PLK21.04216280
44HIPK21.03019828
45TXK1.02420166
46MAP3K141.01680933
47MAP3K20.99826312
48MAP2K70.96987224
49CDK90.95579495
50PKN10.92688253
51SGK10.90963022
52MARK20.89663994
53SIK20.88805699
54STK30.87162634
55ERBB30.86006827
56NTRK20.83308820
57ATM0.82820179
58PAK30.80952050
59MAPK70.80191310
60DYRK1A0.79051123
61OXSR10.78147754
62PINK10.73787356
63PRKAA20.73603739
64EIF2AK20.72454492
65PIK3CG0.71651203
66DMPK0.69143782
67IRAK40.69061234
68FGFR30.69045310
69IRAK20.68956462
70MAP3K100.68113885
71BCR0.67393211
72CHUK0.66403144
73ATR0.65980436
74DAPK20.64952500
75IRAK30.64293751
76STK390.63516628
77SIK30.62841364
78CDC70.62826298
79FGFR10.62259156
80CSNK1E0.61504767
81EPHA40.60644147
82STK240.60498116
83RPS6KB10.59897733
84BMPR20.59129099
85NLK0.58941910
86GSK3B0.58005815
87EPHA30.57907283
88MAPK100.57060916
89NEK20.56781175
90CDC42BPA0.55856309
91CAMK40.55411606
92PRKD20.55075435
93MAPK140.54827346
94PRKG10.53064639
95PDGFRB0.52450158
96IRAK10.52409532
97MINK10.51864583
98JAK10.51566631
99CLK10.50826096
100CSNK1D0.48172976
101TGFBR10.48080803
102CHEK10.48059585
103CSNK1G10.47786526
104PRKCE0.47575161
105MTOR0.46589343
106MAP2K40.46214982
107PRKDC0.45745916
108CDK10.45727390
109MAPK150.45637018
110CAMKK20.44089067
111FER0.43739987
112MAPK80.43730903
113RIPK10.43676082
114DYRK30.42960240
115AKT10.42866044
116SIK10.42813896
117MAP3K40.42804706
118EEF2K0.42768732
119CHEK20.42629913
120PHKG10.42048083
121PHKG20.42048083
122ERBB20.41353375
123PRKCG0.41004857
124TEC0.40658527
125CDK60.40015153
126CDK20.39886228
127CAMK10.39642291
128ADRBK20.39158147
129MAP3K70.39145916
130CSNK1G20.38680550
131TRPM70.37920252
132CDK80.37899353
133MAP3K130.37241397
134PRKAA10.35477211
135STK110.34600899
136MAPK10.34424049
137RPS6KA30.34419872

Predicted pathways (KEGG)

RankGene SetZ-score
1Phototransduction_Homo sapiens_hsa047442.82008653
2Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.85449840
3Lysine degradation_Homo sapiens_hsa003101.75187954
4Fatty acid biosynthesis_Homo sapiens_hsa000611.74218187
5Butanoate metabolism_Homo sapiens_hsa006501.69372546
6Nicotine addiction_Homo sapiens_hsa050331.58638615
7Circadian rhythm_Homo sapiens_hsa047101.52020415
8Fanconi anemia pathway_Homo sapiens_hsa034601.47307063
9Type II diabetes mellitus_Homo sapiens_hsa049301.41843322
10Glutamatergic synapse_Homo sapiens_hsa047241.38967863
11Phosphatidylinositol signaling system_Homo sapiens_hsa040701.37950200
12Morphine addiction_Homo sapiens_hsa050321.36246541
13Insulin secretion_Homo sapiens_hsa049111.31901213
14Circadian entrainment_Homo sapiens_hsa047131.31895351
15Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.29891057
16Linoleic acid metabolism_Homo sapiens_hsa005911.28140657
17Selenocompound metabolism_Homo sapiens_hsa004501.26680876
18alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.25749015
19Taste transduction_Homo sapiens_hsa047421.25135651
20Propanoate metabolism_Homo sapiens_hsa006401.25080056
21Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.21958118
22Olfactory transduction_Homo sapiens_hsa047401.18436354
23Wnt signaling pathway_Homo sapiens_hsa043101.17258638
24Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.17234023
25Nitrogen metabolism_Homo sapiens_hsa009101.16864220
26Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.16691140
27Transcriptional misregulation in cancer_Homo sapiens_hsa052021.15553281
28Serotonergic synapse_Homo sapiens_hsa047261.15421308
29Basal cell carcinoma_Homo sapiens_hsa052171.14686001
30Maturity onset diabetes of the young_Homo sapiens_hsa049501.14060097
31Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.13588575
32Inositol phosphate metabolism_Homo sapiens_hsa005621.12404003
33Axon guidance_Homo sapiens_hsa043601.12210507
34Renin secretion_Homo sapiens_hsa049241.11519968
35cAMP signaling pathway_Homo sapiens_hsa040241.08716048
36Ovarian steroidogenesis_Homo sapiens_hsa049131.08398295
37Cholinergic synapse_Homo sapiens_hsa047251.07020870
38Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.05792252
39Dorso-ventral axis formation_Homo sapiens_hsa043201.05534435
40Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.02980893
41Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.02407873
42Autoimmune thyroid disease_Homo sapiens_hsa053201.02052089
43Non-homologous end-joining_Homo sapiens_hsa034501.01782686
44Aldosterone synthesis and secretion_Homo sapiens_hsa049251.01336932
45Prostate cancer_Homo sapiens_hsa052151.01020172
46Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.99810888
47RNA degradation_Homo sapiens_hsa030180.98976212
48Long-term depression_Homo sapiens_hsa047300.97847560
49Amphetamine addiction_Homo sapiens_hsa050310.97207381
50GABAergic synapse_Homo sapiens_hsa047270.97195869
51Notch signaling pathway_Homo sapiens_hsa043300.93698461
52ErbB signaling pathway_Homo sapiens_hsa040120.93482993
53Long-term potentiation_Homo sapiens_hsa047200.91683104
54Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.91229312
55cGMP-PKG signaling pathway_Homo sapiens_hsa040220.90830844
56MicroRNAs in cancer_Homo sapiens_hsa052060.89845545
57Calcium signaling pathway_Homo sapiens_hsa040200.89845461
58Cocaine addiction_Homo sapiens_hsa050300.88948733
59Adherens junction_Homo sapiens_hsa045200.88188739
60Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.87283727
61Hedgehog signaling pathway_Homo sapiens_hsa043400.87159504
62Dopaminergic synapse_Homo sapiens_hsa047280.86850561
63Thyroid hormone signaling pathway_Homo sapiens_hsa049190.85799027
64Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.85341837
65Choline metabolism in cancer_Homo sapiens_hsa052310.85208517
66mRNA surveillance pathway_Homo sapiens_hsa030150.84432465
67MAPK signaling pathway_Homo sapiens_hsa040100.83467442
68NF-kappa B signaling pathway_Homo sapiens_hsa040640.82721753
69Homologous recombination_Homo sapiens_hsa034400.82049509
70Ether lipid metabolism_Homo sapiens_hsa005650.81924346
71Sphingolipid metabolism_Homo sapiens_hsa006000.81395578
72Salivary secretion_Homo sapiens_hsa049700.80605392
73Thyroid hormone synthesis_Homo sapiens_hsa049180.78592789
74Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.78548579
75Dilated cardiomyopathy_Homo sapiens_hsa054140.76876547
76Hematopoietic cell lineage_Homo sapiens_hsa046400.76110475
77Melanogenesis_Homo sapiens_hsa049160.75765114
78Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.75595339
79TGF-beta signaling pathway_Homo sapiens_hsa043500.75274602
80Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.74733948
81Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.74200468
82NOD-like receptor signaling pathway_Homo sapiens_hsa046210.73035539
83SNARE interactions in vesicular transport_Homo sapiens_hsa041300.72925440
84RNA transport_Homo sapiens_hsa030130.72246857
85Oocyte meiosis_Homo sapiens_hsa041140.71985743
86Vascular smooth muscle contraction_Homo sapiens_hsa042700.71477614
87Jak-STAT signaling pathway_Homo sapiens_hsa046300.70071673
88Estrogen signaling pathway_Homo sapiens_hsa049150.69805887
89Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.69695970
90Endometrial cancer_Homo sapiens_hsa052130.69664203
91Regulation of autophagy_Homo sapiens_hsa041400.69620455
92FoxO signaling pathway_Homo sapiens_hsa040680.69204983
93Oxytocin signaling pathway_Homo sapiens_hsa049210.68881965
94Ras signaling pathway_Homo sapiens_hsa040140.68871394
95T cell receptor signaling pathway_Homo sapiens_hsa046600.68479153
96Melanoma_Homo sapiens_hsa052180.68433715
97Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.68392600
98ABC transporters_Homo sapiens_hsa020100.67250409
99Carbohydrate digestion and absorption_Homo sapiens_hsa049730.66512513
100Longevity regulating pathway - mammal_Homo sapiens_hsa042110.66198171
101Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.66172884
102Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.65866048
103Herpes simplex infection_Homo sapiens_hsa051680.65832940
104Tryptophan metabolism_Homo sapiens_hsa003800.65335808
105Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.64691630
106Gastric acid secretion_Homo sapiens_hsa049710.64317677
107Prolactin signaling pathway_Homo sapiens_hsa049170.64230735
108GnRH signaling pathway_Homo sapiens_hsa049120.63803085
109Measles_Homo sapiens_hsa051620.63515406
110Glucagon signaling pathway_Homo sapiens_hsa049220.63481501
111Tight junction_Homo sapiens_hsa045300.63410176
112Basal transcription factors_Homo sapiens_hsa030220.63259216
113Pathways in cancer_Homo sapiens_hsa052000.62563741
114Glycerophospholipid metabolism_Homo sapiens_hsa005640.61391125
115Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.59457672
116ECM-receptor interaction_Homo sapiens_hsa045120.59423939
117Chemokine signaling pathway_Homo sapiens_hsa040620.59355004
118Primary immunodeficiency_Homo sapiens_hsa053400.58980996
119Pancreatic secretion_Homo sapiens_hsa049720.58889794
120Steroid biosynthesis_Homo sapiens_hsa001000.58646679
121Small cell lung cancer_Homo sapiens_hsa052220.58211578
122Hippo signaling pathway_Homo sapiens_hsa043900.56668295
123mTOR signaling pathway_Homo sapiens_hsa041500.55180351
124Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.54670225
125Rap1 signaling pathway_Homo sapiens_hsa040150.53882704
126PI3K-Akt signaling pathway_Homo sapiens_hsa041510.53609891
127Gap junction_Homo sapiens_hsa045400.53423883
128Colorectal cancer_Homo sapiens_hsa052100.52838522
129Insulin resistance_Homo sapiens_hsa049310.52491800

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