UBQLN4

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1daunorubicin metabolic process (GO:0044597)8.67333043
2polyketide metabolic process (GO:0030638)8.67333043
3doxorubicin metabolic process (GO:0044598)8.67333043
4protein localization to kinetochore (GO:0034501)6.45513676
5maintenance of protein location in nucleus (GO:0051457)5.92408244
6regulation of mammary gland epithelial cell proliferation (GO:0033599)5.76197339
7aminoglycoside antibiotic metabolic process (GO:0030647)5.61569094
8regulation of telomere maintenance via telomerase (GO:0032210)5.57624412
9histone H4-K12 acetylation (GO:0043983)5.54336654
10histone H4-K5 acetylation (GO:0043981)5.52765724
11histone H4-K8 acetylation (GO:0043982)5.52765724
12negative regulation of G2/M transition of mitotic cell cycle (GO:0010972)5.49558761
13negative regulation of telomerase activity (GO:0051974)5.46003957
14somite rostral/caudal axis specification (GO:0032525)5.36875405
15heterochromatin organization (GO:0070828)5.30619062
16regulation of nuclear cell cycle DNA replication (GO:0033262)5.30531824
17negative regulation of epidermis development (GO:0045683)5.29116075
18negative regulation of intracellular estrogen receptor signaling pathway (GO:0033147)5.27327777
19pre-miRNA processing (GO:0031054)5.01550005
20mitotic sister chromatid segregation (GO:0000070)5.00843388
21regulation of response to osmotic stress (GO:0047484)4.95537984
22negative regulation of cell cycle G2/M phase transition (GO:1902750)4.94785069
23nuclear pore complex assembly (GO:0051292)4.93259399
24rRNA transcription (GO:0009303)4.77250835
25notochord development (GO:0030903)4.74906508
26protein localization to chromosome, centromeric region (GO:0071459)4.69167719
27muscle organ morphogenesis (GO:0048644)4.63227713
28DNA replication-dependent nucleosome assembly (GO:0006335)4.54851134
29DNA replication-dependent nucleosome organization (GO:0034723)4.54851134
30nuclear pore organization (GO:0006999)4.54387134
31chromatin assembly (GO:0031497)4.46586712
32negative regulation of potassium ion transmembrane transporter activity (GO:1901017)4.38996370
33Golgi transport vesicle coating (GO:0048200)4.36130652
34COPI coating of Golgi vesicle (GO:0048205)4.36130652
35sister chromatid segregation (GO:0000819)4.32291643
36regulation of translational fidelity (GO:0006450)4.26507054
37regulation of posttranscriptional gene silencing (GO:0060147)4.24569615
38regulation of gene silencing by miRNA (GO:0060964)4.24569615
39regulation of gene silencing by RNA (GO:0060966)4.24569615
40histone H4-K16 acetylation (GO:0043984)4.24197718
41regulation of MHC class I biosynthetic process (GO:0045343)4.16761002
42positive regulation of DNA-dependent DNA replication (GO:2000105)4.10517487
43hormone catabolic process (GO:0042447)4.09237683
44proline biosynthetic process (GO:0006561)4.09117783
45negative regulation of epidermal cell differentiation (GO:0045605)3.91833058
46primitive streak formation (GO:0090009)3.89688796
47planar cell polarity pathway involved in neural tube closure (GO:0090179)3.83013682
48mRNA stabilization (GO:0048255)3.81269533
49RNA stabilization (GO:0043489)3.81269533
50maternal placenta development (GO:0001893)3.77402984
51regulation of translation in response to stress (GO:0043555)3.73135166
52branching involved in mammary gland duct morphogenesis (GO:0060444)3.71003730
53negative regulation of telomere maintenance (GO:0032205)3.70051521
54cell fate commitment involved in formation of primary germ layer (GO:0060795)3.63979241
55cellular modified amino acid catabolic process (GO:0042219)3.61332429
56regulation of hippo signaling (GO:0035330)3.60739064
57regulation of intracellular estrogen receptor signaling pathway (GO:0033146)3.58770459
58DNA duplex unwinding (GO:0032508)3.57640126
59positive regulation of protein deacetylation (GO:0090312)3.56454908
60regulation of apoptotic process involved in morphogenesis (GO:1902337)3.54988422
61DNA geometric change (GO:0032392)3.53554339
62cytidine metabolic process (GO:0046087)3.53180794
63cytidine catabolic process (GO:0006216)3.53180794
64cytidine deamination (GO:0009972)3.53180794
65positive regulation of histone deacetylation (GO:0031065)3.52732028
66DNA unwinding involved in DNA replication (GO:0006268)3.52101433
67regulation of early endosome to late endosome transport (GO:2000641)3.51983623
68response to dietary excess (GO:0002021)3.50848265
69cytoskeletal anchoring at plasma membrane (GO:0007016)3.50783553
70pore complex assembly (GO:0046931)3.48541670
71DNA replication checkpoint (GO:0000076)3.47737324
72regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)3.46799540
73negative regulation of potassium ion transmembrane transport (GO:1901380)3.46538142
74intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator (GO:0042771)3.46038348
75adherens junction assembly (GO:0034333)3.45490182
76NLS-bearing protein import into nucleus (GO:0006607)3.44077050
77spliceosomal tri-snRNP complex assembly (GO:0000244)3.43833832
78coenzyme catabolic process (GO:0009109)3.43085727
79regulation of telomere maintenance (GO:0032204)3.42345483
80nucleoside transmembrane transport (GO:1901642)3.41948315
81retrograde vesicle-mediated transport, Golgi to ER (GO:0006890)3.41462770
82maintenance of protein localization in organelle (GO:0072595)3.41136480
83intestinal epithelial cell development (GO:0060576)3.37878629
84rRNA methylation (GO:0031167)3.36810535
85regulation of cilium movement (GO:0003352)3.35622734
86protein retention in ER lumen (GO:0006621)3.35497679
87trophectodermal cell differentiation (GO:0001829)3.34895028
88phenol-containing compound catabolic process (GO:0019336)3.34353379
89retinoic acid receptor signaling pathway (GO:0048384)3.33513178
90maintenance of protein localization in endoplasmic reticulum (GO:0035437)3.32035696
91regulation of NFAT protein import into nucleus (GO:0051532)3.31499921
92intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress (GO:0070059)3.30427034
93protein complex localization (GO:0031503)3.29796151
94mitochondrion distribution (GO:0048311)3.28402627
95intracellular estrogen receptor signaling pathway (GO:0030520)3.23601210
96cardiovascular system development (GO:0072358)3.22598922
97proline transport (GO:0015824)3.22570322
98nucleosome disassembly (GO:0006337)3.22217120
99protein-DNA complex disassembly (GO:0032986)3.22217120
100regulation of telomerase activity (GO:0051972)3.20426589
101mitotic chromosome condensation (GO:0007076)3.19964020
102focal adhesion assembly (GO:0048041)3.19870421
103cell-substrate adherens junction assembly (GO:0007045)3.19870421
104formation of translation preinitiation complex (GO:0001731)3.19628323
105regulation of RNA export from nucleus (GO:0046831)3.19291445
106cellular protein complex localization (GO:0034629)3.17154778
107activation of Rac GTPase activity (GO:0032863)3.16805219
108transcription from mitochondrial promoter (GO:0006390)3.14680120
109positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling3.14649886
110ribosome biogenesis (GO:0042254)3.13225057
111rRNA modification (GO:0000154)3.11603475
112regulation of nucleobase-containing compound transport (GO:0032239)3.11291104
113negative regulation of mRNA splicing, via spliceosome (GO:0048025)3.11112303
114histone arginine methylation (GO:0034969)3.05875940
115apoptotic process involved in morphogenesis (GO:0060561)3.05679160
116quinone metabolic process (GO:1901661)3.04104968
117apoptotic DNA fragmentation (GO:0006309)3.03910824
118negative regulation of cell size (GO:0045792)3.02145661
119cell migration involved in gastrulation (GO:0042074)3.00092637
120interferon-gamma production (GO:0032609)2.97134154
121cell migration in hindbrain (GO:0021535)2.94840664
122proline metabolic process (GO:0006560)2.92558812
123peptidyl-arginine omega-N-methylation (GO:0035247)2.92233875
124anterior/posterior axis specification, embryo (GO:0008595)2.89053600
125regulation of mitotic spindle organization (GO:0060236)2.87063027
126protein export from nucleus (GO:0006611)2.86320079
127vitamin A metabolic process (GO:0006776)2.85222045
128negative regulation of gene silencing (GO:0060969)2.84802625
129DNA topological change (GO:0006265)2.84144338
130epoxygenase P450 pathway (GO:0019373)2.83560222
131microtubule severing (GO:0051013)2.83278280
132anterior/posterior axis specification (GO:0009948)2.82963134
133sodium ion export (GO:0071436)2.81392213
134convergent extension (GO:0060026)2.81319439
135regulation of glucose import in response to insulin stimulus (GO:2001273)2.79459265
136regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway 2.79177137
137positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling2.79177137
138layer formation in cerebral cortex (GO:0021819)2.77806779
139positive regulation of synapse maturation (GO:0090129)2.76282384
140semaphorin-plexin signaling pathway (GO:0071526)2.72308508
141regulation of branching involved in prostate gland morphogenesis (GO:0060687)2.71959400
142mitotic sister chromatid cohesion (GO:0007064)2.71661781
1433-UTR-mediated mRNA stabilization (GO:0070935)2.67405206
144L-serine metabolic process (GO:0006563)2.66245848
145peptidyl-lysine dimethylation (GO:0018027)2.65004513
146protein localization to endosome (GO:0036010)2.63359182
147regulation of histone H3-K27 methylation (GO:0061085)2.62531548
148RNA localization (GO:0006403)2.61699751
149histone H2B ubiquitination (GO:0033523)2.60972539
150glucocorticoid receptor signaling pathway (GO:0042921)2.60877774
151ribosomal small subunit biogenesis (GO:0042274)2.60841081
152activation of signaling protein activity involved in unfolded protein response (GO:0006987)2.60167150
153Wnt signaling pathway, planar cell polarity pathway (GO:0060071)2.56397889
154positive regulation of nuclease activity (GO:0032075)2.56215654
155pentose-phosphate shunt (GO:0006098)2.55321531
156cerebellar granule cell differentiation (GO:0021707)2.54437108
157cochlea morphogenesis (GO:0090103)2.53111320
158synaptic vesicle docking involved in exocytosis (GO:0016081)2.52381621
159glucose 6-phosphate metabolic process (GO:0051156)2.50717155
160cellular response to epidermal growth factor stimulus (GO:0071364)2.50535404
161negative regulation of microtubule polymerization (GO:0031115)2.50228332
162protein localization to microtubule (GO:0035372)2.50040398
163peptidyl-arginine N-methylation (GO:0035246)2.48673154
164peptidyl-arginine methylation (GO:0018216)2.48673154
165DNA replication initiation (GO:0006270)2.44809884
166regulation of chromatin binding (GO:0035561)2.43351027
167cell-substrate junction assembly (GO:0007044)2.43025611
168stress granule assembly (GO:0034063)2.41385348
169regulation of establishment of planar polarity (GO:0090175)2.39859533
170modulation by virus of host morphology or physiology (GO:0019048)2.39086446
171regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway 2.38872283
172negative regulation of mRNA processing (GO:0050686)2.37128493
173chromosome condensation (GO:0030261)2.36932779
174negative regulation of mRNA metabolic process (GO:1903312)2.36528181
175nucleobase-containing small molecule interconversion (GO:0015949)2.35530618
176response to epidermal growth factor (GO:0070849)2.34733540
177mitotic G1 DNA damage checkpoint (GO:0031571)2.30792096
178epithelial cell differentiation involved in prostate gland development (GO:0060742)2.29970907
179response to parathyroid hormone (GO:0071107)2.28870628
180paraxial mesoderm development (GO:0048339)2.28226797
181DNA strand elongation involved in DNA replication (GO:0006271)2.28163906
182G1 DNA damage checkpoint (GO:0044783)2.26644466
183DNA strand elongation (GO:0022616)2.25729940

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1KLF5_18264089_ChIP-ChIP_MESCs_Mouse5.52083041
2KLF4_18264089_ChIP-ChIP_MESCs_Mouse5.52083041
3KLF2_18264089_ChIP-ChIP_MESCs_Mouse5.52083041
4E2F7_22180533_ChIP-Seq_HELA_Human5.06894420
5BP1_19119308_ChIP-ChIP_Hs578T_Human4.23708340
6NACC1_18358816_ChIP-ChIP_MESCs_Mouse3.17291016
7SMAD1_18555785_ChIP-Seq_MESCs_Mouse3.02861002
8POU5F1_18700969_ChIP-ChIP_MESCs_Mouse3.01417642
9NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.92680370
10SMAD3_22036565_ChIP-Seq_ESCs_Mouse2.86353419
11SOX2_18358816_ChIP-ChIP_MESCs_Mouse2.72826353
12FOXM1_23109430_ChIP-Seq_U2OS_Human2.62120978
13ZFP281_18358816_ChIP-ChIP_MESCs_Mouse2.50211137
14NANOG_18700969_ChIP-ChIP_MESCs_Mouse2.46282011
15TP63_17297297_ChIP-ChIP_HaCaT_Human2.43121577
16TP63_19390658_ChIP-ChIP_HaCaT_Human2.42497768
17TCF3_18692474_ChIP-Seq_MEFs_Mouse2.39548169
18TCF3_18692474_ChIP-Seq_MESCs_Mouse2.38787262
19HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.33345040
20ZNF263_19887448_ChIP-Seq_K562_Human2.29074977
21THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse2.28348983
22E2F4_17652178_ChIP-ChIP_JURKAT_Human2.28031639
23MYC_22102868_ChIP-Seq_BL_Human2.02820864
24STAT3_1855785_ChIP-Seq_MESCs_Mouse2.02724898
25NR0B1_18358816_ChIP-ChIP_MESCs_Mouse2.02427178
26MYC_18555785_ChIP-Seq_MESCs_Mouse1.96956929
27NANOG_18347094_ChIP-ChIP_MESCs_Mouse1.96809187
28ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.96521773
29VDR_21846776_ChIP-Seq_THP-1_Human1.96049613
30ZFP281_18757296_ChIP-ChIP_E14_Mouse1.94047735
31MYC_19079543_ChIP-ChIP_MESCs_Mouse1.90646738
32SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.84568576
33KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.84307501
34* CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.80350926
35NANOG_18358816_ChIP-ChIP_MESCs_Mouse1.78266260
36DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.77951736
37PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.77585211
38ERG_21242973_ChIP-ChIP_JURKAT_Human1.77356437
39HIF1A_21447827_ChIP-Seq_MCF-7_Human1.73552658
40* EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.71519285
41ZFP281_27345836_Chip-Seq_ESCs_Mouse1.70439469
42TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.70039510
43* POU5F1_16518401_ChIP-PET_MESCs_Mouse1.68899204
44RARG_19884340_ChIP-ChIP_MEFs_Mouse1.68375976
45FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.67690308
46ZFX_18555785_ChIP-Seq_MESCs_Mouse1.64224635
47POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.63475316
48SRY_22984422_ChIP-ChIP_TESTIS_Rat1.60956211
49CLOCK_20551151_ChIP-Seq_293T_Human1.60844696
50NANOG_18555785_ChIP-Seq_MESCs_Mouse1.60454551
51CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.56467346
52TCF3_18347094_ChIP-ChIP_MESCs_Mouse1.52300813
53EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.51101295
54* P300_27058665_Chip-Seq_ZR-75-30cells_Human1.50259954
55RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.49623597
56* KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.47045597
57UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.46720119
58* MYC_19030024_ChIP-ChIP_MESCs_Mouse1.46310662
59SOX2_18555785_ChIP-Seq_MESCs_Mouse1.45667503
60TET1_21451524_ChIP-Seq_MESCs_Mouse1.45636091
61ESR2_21235772_ChIP-Seq_MCF-7_Human1.42978864
62NANOG_18692474_ChIP-Seq_MESCs_Mouse1.41955328
63TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.41626218
64* NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.40074384
65POU5F1_18692474_ChIP-Seq_MESCs_Mouse1.39020929
66POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.38131615
67OCT4_18692474_ChIP-Seq_MEFs_Mouse1.37877438
68NANOG_18692474_ChIP-Seq_MEFs_Mouse1.37852732
69PRDM14_21183938_ChIP-Seq_MESCs_Mouse1.37516715
70CREB1_26743006_Chip-Seq_LNCaP_Human1.34849001
71SOX2_18692474_ChIP-Seq_MESCs_Mouse1.33157669
72* EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.33123591
73ESR1_15608294_ChIP-ChIP_MCF-7_Human1.31597641
74KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.31140631
75* THAP11_20581084_ChIP-Seq_MESCs_Mouse1.31030161
76EGR1_19374776_ChIP-ChIP_THP-1_Human1.30319844
77TCF7_22412390_ChIP-Seq_EML_Mouse1.28371288
78MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.27742942
79KDM2B_26808549_Chip-Seq_JURKAT_Human1.27165568
80KDM2B_26808549_Chip-Seq_SUP-B15_Human1.26791578
81KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.25351994
82NANOG_21062744_ChIP-ChIP_HESCs_Human1.24262948
83RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.23893930
84CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.22702000
85SA1_27219007_Chip-Seq_ERYTHROID_Human1.22679769
86* CTCF_27219007_Chip-Seq_ERYTHROID_Human1.22618567
87SOX2_18692474_ChIP-Seq_MEFs_Mouse1.22108614
88* MYCN_18555785_ChIP-Seq_MESCs_Mouse1.20241396
89* MYC_18358816_ChIP-ChIP_MESCs_Mouse1.18464296
90DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.17036925
91SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.15388715
92* SREBP1_19666523_ChIP-Seq_LIVER_Mouse1.14909088
93NELFA_20434984_ChIP-Seq_ESCs_Mouse1.13929987
94* NANOG_16518401_ChIP-PET_MESCs_Mouse1.13394683
95E2F1_17053090_ChIP-ChIP_MCF-7_Human1.13375070
96KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.11155871
97RARB_27405468_Chip-Seq_BRAIN_Mouse1.10348086
98MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.10137261
99NCOR1_26117541_ChIP-Seq_K562_Human1.09988446
100SREBP2_21459322_ChIP-Seq_LIVER_Mouse1.09714583
101TP53_22127205_ChIP-Seq_IMR90_Human1.09177705
102ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.08286216
103DNAJC2_21179169_ChIP-ChIP_NT2_Human1.07227323
104ELK3_25401928_ChIP-Seq_HUVEC_Human1.07177994
105WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.06461406
106* KLF4_18555785_ChIP-Seq_MESCs_Mouse1.05173722
107* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.03825718
108E2F1_21310950_ChIP-Seq_MCF-7_Human1.03077832
109RACK7_27058665_Chip-Seq_MCF-7_Human1.02850129
110CHD1_26751641_Chip-Seq_LNCaP_Human1.02787517
111LXR_22292898_ChIP-Seq_THP-1_Human1.02712032
112KDM2B_26808549_Chip-Seq_K562_Human1.01641409
113YY1_21170310_ChIP-Seq_MESCs_Mouse1.01581347
114ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.01529587
115CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.01382620
116IRF1_19129219_ChIP-ChIP_H3396_Human1.01309215
117POU5F1_18347094_ChIP-ChIP_MESCs_Mouse1.01077541
118CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.00816687
119PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.00489721
120TFAP2A_17053090_ChIP-ChIP_MCF-7_Human0.98910790
121* MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human0.98447039
122SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.98096564
123RUNX1_27514584_Chip-Seq_MCF-7_Human0.97705907
124CDX2_20551321_ChIP-Seq_CACO-2_Human0.97494060
125NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse0.96903905
126KDM2B_26808549_Chip-Seq_DND41_Human0.91857118
127SMC4_20622854_ChIP-Seq_HELA_Human0.91609067
128ESRRB_18555785_ChIP-Seq_MESCs_Mouse0.90173574
129KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.89542305
130P68_20966046_ChIP-Seq_HELA_Human0.89126425
131TCF3_18467660_ChIP-ChIP_MESCs_Mouse0.88700015
132CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.88344597
133SETDB1_19884255_ChIP-Seq_MESCs_Mouse0.88142909
134TBX3_20139965_ChIP-Seq_ESCs_Mouse0.87456482
135TBX3_20139965_ChIP-Seq_MESCs_Mouse0.85720921
136* NANOG_16153702_ChIP-ChIP_HESCs_Human0.84755991
137AR_21909140_ChIP-Seq_LNCAP_Human0.84293947
138KAP1_27257070_Chip-Seq_ESCs_Mouse0.84293022
139ELF1_20517297_ChIP-Seq_JURKAT_Human0.83688476
140KDM2B_26808549_Chip-Seq_HPB-ALL_Human0.82835536
141TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.80511410
142XRN2_22483619_ChIP-Seq_HELA_Human0.80013352
143TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.80002538
144STAT6_21828071_ChIP-Seq_BEAS2B_Human0.79923986
145KDM5A_27292631_Chip-Seq_BREAST_Human0.78600407
146YY1_22570637_ChIP-Seq_MALME-3M_Human0.76862558
147STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse0.76491349
148ATF3_27146783_Chip-Seq_COLON_Human0.76390922

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004264_abnormal_extraembryonic_tissu3.99891835
2MP0002254_reproductive_system_inflammat3.80137806
3MP0003705_abnormal_hypodermis_morpholog3.47769996
4MP0003890_abnormal_embryonic-extraembry3.47351743
5MP0003011_delayed_dark_adaptation3.38023666
6MP0004858_abnormal_nervous_system3.22267797
7MP0006292_abnormal_olfactory_placode3.21336589
8MP0004957_abnormal_blastocyst_morpholog2.91270090
9MP0008057_abnormal_DNA_replication2.86152674
10MP0005499_abnormal_olfactory_system2.83028221
11MP0005394_taste/olfaction_phenotype2.83028221
12MP0010352_gastrointestinal_tract_polyps2.79036774
13MP0003122_maternal_imprinting2.67962222
14MP0005451_abnormal_body_composition2.66738853
15MP0002653_abnormal_ependyma_morphology2.47783802
16MP0002332_abnormal_exercise_endurance2.45114086
17MP0004233_abnormal_muscle_weight2.40922554
18MP0000537_abnormal_urethra_morphology2.30544748
19MP0003121_genomic_imprinting2.26772703
20MP0010234_abnormal_vibrissa_follicle2.18572673
21MP0008961_abnormal_basal_metabolism2.18341155
22MP0000566_synostosis2.18116871
23MP0005075_abnormal_melanosome_morpholog2.15565803
24MP0005380_embryogenesis_phenotype2.13995506
25MP0001672_abnormal_embryogenesis/_devel2.13995506
26MP0001346_abnormal_lacrimal_gland2.11440133
27MP0003123_paternal_imprinting2.06490842
28MP0009672_abnormal_birth_weight2.03385156
29MP0006035_abnormal_mitochondrial_morpho2.02828468
30MP0002088_abnormal_embryonic_growth/wei2.01269897
31MP0003984_embryonic_growth_retardation2.00083332
32MP0001849_ear_inflammation1.90633485
33MP0010030_abnormal_orbit_morphology1.88328182
34MP0005409_darkened_coat_color1.87521864
35MP0004859_abnormal_synaptic_plasticity1.85712336
36MP0003283_abnormal_digestive_organ1.82254849
37MP0000350_abnormal_cell_proliferation1.72214666
38MP0009053_abnormal_anal_canal1.68501143
39MP0005257_abnormal_intraocular_pressure1.68307277
40MP0000579_abnormal_nail_morphology1.67638355
41MP0002086_abnormal_extraembryonic_tissu1.64863255
42MP0002796_impaired_skin_barrier1.63639394
43MP0000678_abnormal_parathyroid_gland1.62506458
44MP0003077_abnormal_cell_cycle1.61522122
45MP0002084_abnormal_developmental_patter1.60810652
46MP0002085_abnormal_embryonic_tissue1.59143760
47MP0003111_abnormal_nucleus_morphology1.58826535
48MP0001293_anophthalmia1.58444529
49MP0002127_abnormal_cardiovascular_syste1.55278970
50MP0003119_abnormal_digestive_system1.53835244
51MP0004133_heterotaxia1.50522306
52MP0001730_embryonic_growth_arrest1.49156168
53MP0004197_abnormal_fetal_growth/weight/1.48412273
54MP0005058_abnormal_lysosome_morphology1.47963463
55MP0000751_myopathy1.47089035
56MP0000733_abnormal_muscle_development1.45995699
57MP0003453_abnormal_keratinocyte_physiol1.45389320
58MP0003942_abnormal_urinary_system1.44830053
59MP0002089_abnormal_postnatal_growth/wei1.42483154
60MP0005501_abnormal_skin_physiology1.41801011
61MP0003938_abnormal_ear_development1.40169507
62MP0000534_abnormal_ureter_morphology1.37751351
63MP0005266_abnormal_metabolism1.36476911
64MP0002092_abnormal_eye_morphology1.33944793
65MP0002269_muscular_atrophy1.33630046
66MP0003329_amyloid_beta_deposits1.32271123
67MP0005666_abnormal_adipose_tissue1.31833593
68MP0002932_abnormal_joint_morphology1.29148921
69MP0010094_abnormal_chromosome_stability1.28214182
70MP0002697_abnormal_eye_size1.27500972
71MP0001697_abnormal_embryo_size1.26645363
72MP0003115_abnormal_respiratory_system1.25045187
73MP0000750_abnormal_muscle_regeneration1.21619292
74MP0008770_decreased_survivor_rate1.19157293
75MP0000747_muscle_weakness1.17483015
76MP0004270_analgesia1.16299419
77MP0003137_abnormal_impulse_conducting1.15760124
78MP0002080_prenatal_lethality1.15129969
79MP0000762_abnormal_tongue_morphology1.14452333
80MP0000462_abnormal_digestive_system1.14398948
81MP0002396_abnormal_hematopoietic_system1.13020849
82MP0000428_abnormal_craniofacial_morphol1.12732436
83MP0000749_muscle_degeneration1.08294703
84MP0003385_abnormal_body_wall1.06705895
85MP0000003_abnormal_adipose_tissue1.06428064
86MP0002114_abnormal_axial_skeleton1.04978288
87MP0003935_abnormal_craniofacial_develop1.04640805
88MP0009780_abnormal_chondrocyte_physiolo1.03743494
89MP0002925_abnormal_cardiovascular_devel1.03015048
90MP0002970_abnormal_white_adipose1.02191129
91MP0000467_abnormal_esophagus_morphology1.01590335
92MP0005375_adipose_tissue_phenotype1.01298631
93MP0000049_abnormal_middle_ear1.01252634
94MP0002233_abnormal_nose_morphology1.00983651
95MP0008789_abnormal_olfactory_epithelium1.00277456
96MP0002098_abnormal_vibrissa_morphology0.99769656
97MP0001348_abnormal_lacrimal_gland0.98813117
98MP0005248_abnormal_Harderian_gland0.97471156
99MP0000432_abnormal_head_morphology0.96059956
100MP0008260_abnormal_autophagy0.94907973
101MP0005623_abnormal_meninges_morphology0.93849692
102MP0009703_decreased_birth_body0.93822719
103MP0000313_abnormal_cell_death0.93686112
104MP0003787_abnormal_imprinting0.92644787
105MP0003634_abnormal_glial_cell0.91592624
106MP0004782_abnormal_surfactant_physiolog0.90709302
107MP0003755_abnormal_palate_morphology0.85286761
108MP0004043_abnormal_pH_regulation0.84715725
109MP0000377_abnormal_hair_follicle0.84001191
110MP0002249_abnormal_larynx_morphology0.83652222
111MP0010630_abnormal_cardiac_muscle0.82701895
112MP0005621_abnormal_cell_physiology0.82077606
113MP0004087_abnormal_muscle_fiber0.81627241
114MP0002060_abnormal_skin_morphology0.81439191
115MP0000627_abnormal_mammary_gland0.80817461
116MP0000759_abnormal_skeletal_muscle0.80793668
117MP0005023_abnormal_wound_healing0.80643773
118MP0003861_abnormal_nervous_system0.78548713
119MP0008932_abnormal_embryonic_tissue0.78271307
120MP0001340_abnormal_eyelid_morphology0.78014678
121MP0001915_intracranial_hemorrhage0.77746210
122MP0000490_abnormal_crypts_of0.75763024
123MP0009278_abnormal_bone_marrow0.75455947
124MP0004084_abnormal_cardiac_muscle0.75415738
125MP0005423_abnormal_somatic_nervous0.74720963
126MP0004272_abnormal_basement_membrane0.74409889
127MP0002152_abnormal_brain_morphology0.73956897
128MP0008007_abnormal_cellular_replicative0.73718466
129MP0000358_abnormal_cell_content/0.73268306
130MP0003693_abnormal_embryo_hatching0.72865622
131MP0005076_abnormal_cell_differentiation0.72515775
132MP0004185_abnormal_adipocyte_glucose0.72402504
133MP0006138_congestive_heart_failure0.71870197
134MP0002877_abnormal_melanocyte_morpholog0.71613339
135MP0000266_abnormal_heart_morphology0.70921276
136MP0002081_perinatal_lethality0.70784888
137MP0005330_cardiomyopathy0.70387158
138MP0003091_abnormal_cell_migration0.70278762
139MP0003566_abnormal_cell_adhesion0.70113683
140MP0000681_abnormal_thyroid_gland0.69718054
141MP0000778_abnormal_nervous_system0.69012087
142MP0002116_abnormal_craniofacial_bone0.68962820
143MP0002111_abnormal_tail_morphology0.68607430
144MP0003315_abnormal_perineum_morphology0.67490785
145MP0002277_abnormal_respiratory_mucosa0.66631917
146MP0005391_vision/eye_phenotype0.64854979
147MP0002909_abnormal_adrenal_gland0.61017384
148MP0003183_abnormal_peptide_metabolism0.58881109
149MP0005384_cellular_phenotype0.58733893
150MP0001286_abnormal_eye_development0.58121217

Predicted human phenotypes

RankGene SetZ-score
1Bilateral microphthalmos (HP:0007633)6.57271594
2Hypochromic microcytic anemia (HP:0004840)5.64605345
3Abnormality of the lower motor neuron (HP:0002366)5.44383258
4Hepatoblastoma (HP:0002884)5.15181702
5Ependymoma (HP:0002888)5.13153953
6Multiple enchondromatosis (HP:0005701)5.02114735
7Rib fusion (HP:0000902)4.43192685
8Hyperacusis (HP:0010780)4.29540336
9Neoplasm of striated muscle (HP:0009728)3.96666285
10Astrocytoma (HP:0009592)3.86007972
11Abnormality of the astrocytes (HP:0100707)3.86007972
12Rhabdomyosarcoma (HP:0002859)3.72964106
13Insomnia (HP:0100785)3.38124996
14Testicular atrophy (HP:0000029)3.22301945
15Amyotrophic lateral sclerosis (HP:0007354)3.13744596
16Nephroblastoma (Wilms tumor) (HP:0002667)3.12475268
17Abnormality of the salivary glands (HP:0010286)3.10371101
18Ragged-red muscle fibers (HP:0003200)3.02895910
19Difficulty running (HP:0009046)2.94632031
20Fused cervical vertebrae (HP:0002949)2.94543693
21Embryonal renal neoplasm (HP:0011794)2.87881061
22Short humerus (HP:0005792)2.86164305
23Increased connective tissue (HP:0009025)2.85485430
24Horizontal nystagmus (HP:0000666)2.82916204
25Aplasia/hypoplasia of the humerus (HP:0006507)2.81913125
26Glioma (HP:0009733)2.78381366
27Hyperinsulinemic hypoglycemia (HP:0000825)2.75909986
28Rectovaginal fistula (HP:0000143)2.72945620
29Rectal fistula (HP:0100590)2.72945620
30Abnormal cartilage morphology (HP:0002763)2.71539778
31Trismus (HP:0000211)2.63885864
32Shawl scrotum (HP:0000049)2.63615126
33Chromosomal breakage induced by crosslinking agents (HP:0003221)2.63581632
34Asymmetry of the thorax (HP:0001555)2.61603060
35Preauricular skin tag (HP:0000384)2.59605271
36Resting tremor (HP:0002322)2.58241028
37Renal duplication (HP:0000075)2.57941492
38Pseudobulbar signs (HP:0002200)2.55636667
39Broad face (HP:0000283)2.55402390
40Overriding aorta (HP:0002623)2.53872806
41Achilles tendon contracture (HP:0001771)2.53070301
42Intestinal fistula (HP:0100819)2.52358936
43Neoplasm of the heart (HP:0100544)2.51784439
44Increased nuchal translucency (HP:0010880)2.51545681
45Large earlobe (HP:0009748)2.50372941
46Obstructive sleep apnea (HP:0002870)2.49800959
47Distal lower limb amyotrophy (HP:0008944)2.47133960
48Centrally nucleated skeletal muscle fibers (HP:0003687)2.44962137
49Ulnar bowing (HP:0003031)2.44025620
50Angiofibromas (HP:0010615)2.43088003
51Adenoma sebaceum (HP:0009720)2.43088003
52Hand muscle atrophy (HP:0009130)2.43052082
53Progressive muscle weakness (HP:0003323)2.42994123
54Skin tags (HP:0010609)2.42615127
55Partial duplication of thumb phalanx (HP:0009944)2.42500088
56Elfin facies (HP:0004428)2.39225876
57Generalized hypotonia (HP:0001290)2.38495423
58Vaginal fistula (HP:0004320)2.37094303
59Ankyloglossia (HP:0010296)2.36160412
60Myopathic facies (HP:0002058)2.35112509
61Abnormality of the Achilles tendon (HP:0005109)2.32553437
62Abnormal lung lobation (HP:0002101)2.32190320
63Long palpebral fissure (HP:0000637)2.31726337
64Abnormality of chromosome segregation (HP:0002916)2.29647356
65Malignant neoplasm of the central nervous system (HP:0100836)2.26336629
66Medulloblastoma (HP:0002885)2.25510233
67Hypochromic anemia (HP:0001931)2.23589918
68Chromsome breakage (HP:0040012)2.23286180
69Distal upper limb amyotrophy (HP:0007149)2.23171560
70Upper limb amyotrophy (HP:0009129)2.23171560
71Bifid tongue (HP:0010297)2.22631459
72Truncus arteriosus (HP:0001660)2.22621869
73Hypoplasia of the fovea (HP:0007750)2.22450878
74Aplasia/Hypoplasia of the fovea (HP:0008060)2.22450878
75Tetraplegia (HP:0002445)2.22295901
76Hypopigmentation of the fundus (HP:0007894)2.21375635
77Disproportionate tall stature (HP:0001519)2.20568507
78Abnormality of the pubic bones (HP:0003172)2.19818499
79Patellar dislocation (HP:0002999)2.19324758
80Pointed chin (HP:0000307)2.18600418
81Abnormality of the musculature of the hand (HP:0001421)2.18334681
82Partial duplication of the phalanx of hand (HP:0009999)2.16572642
83Bowel incontinence (HP:0002607)2.15700554
84Flat acetabular roof (HP:0003180)2.13229792
85Supernumerary spleens (HP:0009799)2.13194850
86Aplasia/Hypoplasia of the sternum (HP:0006714)2.11939648
87Vertebral fusion (HP:0002948)2.11922314
88Shallow orbits (HP:0000586)2.11031485
89Exercise-induced muscle cramps (HP:0003710)2.08757654
90Broad distal phalanx of finger (HP:0009836)2.06302622
91Missing ribs (HP:0000921)2.05569471
92Abnormal gallbladder physiology (HP:0012438)2.05549738
93Cholecystitis (HP:0001082)2.05549738
94Short 5th finger (HP:0009237)2.05223871
95Abnormal large intestine physiology (HP:0012700)2.03067339
96Lower limb amyotrophy (HP:0007210)2.03023798
97Upper motor neuron abnormality (HP:0002127)2.02803496
98Hyperparathyroidism (HP:0000843)2.02564865
99Turricephaly (HP:0000262)2.02248360
100Neoplasm of the oral cavity (HP:0100649)2.01969819
101Protrusio acetabuli (HP:0003179)2.00636053
102EMG: neuropathic changes (HP:0003445)2.00427368
103Preauricular pit (HP:0004467)1.99945590
104Periauricular skin pits (HP:0100277)1.99945590
105Cerebral inclusion bodies (HP:0100314)1.99098464
106Heterotopia (HP:0002282)1.98723105
107Distal lower limb muscle weakness (HP:0009053)1.98625839
108Supernumerary ribs (HP:0005815)1.98608582
109Macroorchidism (HP:0000053)1.98353294
110Impulsivity (HP:0100710)1.97307534
111Atrophy/Degeneration involving motor neurons (HP:0007373)1.96789275
112Unilateral renal agenesis (HP:0000122)1.96214676
113Abnormality of the calcaneus (HP:0008364)1.96143019
114Arnold-Chiari malformation (HP:0002308)1.95955070
115Hyperthyroidism (HP:0000836)1.92591478
116Abnormality of the distal phalanx of the thumb (HP:0009617)1.91498465
117Mildly elevated creatine phosphokinase (HP:0008180)1.91425451
118Abnormality of oral frenula (HP:0000190)1.90387189
119Neuroectodermal neoplasm (HP:0030061)1.88699410
120Neuroepithelial neoplasm (HP:0030063)1.88699410
121Nervous tissue neoplasm (HP:0030060)1.88699410
122Obsessive-compulsive behavior (HP:0000722)1.88047256
123Renovascular hypertension (HP:0100817)1.87972429
124Decreased number of large peripheral myelinated nerve fibers (HP:0003387)1.87570305
125Vertebral compression fractures (HP:0002953)1.87410710
126Back pain (HP:0003418)1.87218959
127Anomalous pulmonary venous return (HP:0010772)1.87214556
128Glossoptosis (HP:0000162)1.86550519
129Termporal pattern (HP:0011008)1.86303201
130Insidious onset (HP:0003587)1.86303201
131Pendular nystagmus (HP:0012043)1.86276293
132Aplasia/Hypoplasia of the 5th finger (HP:0006262)1.85669078
133Meckel diverticulum (HP:0002245)1.83818352
134Fasciculations (HP:0002380)1.82269400
135Parkinsonism with favorable response to dopaminergic medication (HP:0002548)1.80861201
136Supernumerary nipples (HP:0002558)1.79940853
137Abnormality of the distal phalanges of the toes (HP:0010182)1.79886824
138Deep palmar crease (HP:0006191)1.79614259
139Malnutrition (HP:0004395)1.79111406
140Thin ribs (HP:0000883)1.79058798
141Reticulocytosis (HP:0001923)1.79002272
142Muscle fibrillation (HP:0010546)1.78796414
143Tongue fasciculations (HP:0001308)1.78624488
144Deviation of the thumb (HP:0009603)1.77652510
145Germ cell neoplasia (HP:0100728)1.77598236
146Hyperventilation (HP:0002883)1.76876179
147Skin pits (HP:0100276)1.76852049
148Overlapping toe (HP:0001845)1.76725501
149Selective tooth agenesis (HP:0001592)1.76284490
150Supernumerary bones of the axial skeleton (HP:0009144)1.75982932
151Exercise-induced myalgia (HP:0003738)1.75908059
152Premature rupture of membranes (HP:0001788)1.75188446
153Amblyopia (HP:0000646)1.74998632
154Abnormality of the phalanges of the hallux (HP:0010057)1.74896937
155Mitral regurgitation (HP:0001653)1.72580908
156Proximal placement of thumb (HP:0009623)1.71882923
157Supranuclear gaze palsy (HP:0000605)1.71712919
158Dysmetric saccades (HP:0000641)1.70996033
159Hammertoe (HP:0001765)1.69902604
160Premature skin wrinkling (HP:0100678)1.69259312
161Cerebral aneurysm (HP:0004944)1.69140652
162Abnormality of the aortic arch (HP:0012303)1.68292879
163Advanced eruption of teeth (HP:0006288)1.67273801
164Septate vagina (HP:0001153)1.66832821
165Deep venous thrombosis (HP:0002625)1.63483820
166Abnormality of the thoracic spine (HP:0100711)1.62955341
167Precocious puberty (HP:0000826)1.62820959
168Urethral obstruction (HP:0000796)1.62104455
169Hypercalcemia (HP:0003072)1.61739646
170Flat cornea (HP:0007720)1.59836066
171Short nail (HP:0001799)1.59824102
172Hypercortisolism (HP:0001578)1.58869615
173Depression (HP:0000716)1.58284537
174Foot dorsiflexor weakness (HP:0009027)1.57962956
175Spinal rigidity (HP:0003306)1.57303945
176Attention deficit hyperactivity disorder (HP:0007018)1.56535478
177Transposition of the great arteries (HP:0001669)1.56501719
178Abnormal connection of the cardiac segments (HP:0011545)1.56501719
179Abnormal ventriculo-arterial connection (HP:0011563)1.56501719
180Midface retrusion (HP:0011800)1.56410178
181Peripheral hypomyelination (HP:0007182)1.53749033
182Spinal cord compression (HP:0002176)1.53737378
183Neurofibrillary tangles (HP:0002185)1.53511428
184Calcaneovalgus deformity (HP:0001848)1.53331839
185Abnormality of skeletal muscle fiber size (HP:0012084)1.52867845
186Aplasia of the phalanges of the hand (HP:0009802)1.51755749

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CDK128.10241408
2GRK54.21405532
3ERN14.19911806
4SMG13.74157781
5GRK63.48373957
6TYRO32.93576935
7TTK2.58086498
8PRPF4B2.50387342
9IRAK32.29093126
10CSF1R2.23623020
11TGFBR22.06491436
12NME22.05515736
13MATK1.98641283
14STK101.95665167
15MAPK71.94603155
16GRK11.87866171
17ADRBK21.87005328
18MAP3K101.74880381
19WNK11.70430483
20GRK71.62386425
21EPHA21.61965027
22MOS1.61567884
23NEK11.55844796
24CDK71.52869600
25NTRK11.48599193
26MST1R1.45623247
27PAK41.44295801
28FGFR41.40477838
29ALK1.39360126
30CAMK41.39177829
31MAP2K41.33077600
32TRIB31.27021465
33LATS21.23901986
34MAP3K91.21312720
35PRKG21.19687949
36BRSK11.15738725
37MARK21.15381868
38RIPK11.14757407
39CDC71.12227984
40CHEK21.12195584
41ARAF1.11347234
42PKN21.10595809
43BRAF1.07714367
44EIF2AK11.06804577
45PLK11.02175679
46MAP3K70.97398269
47MTOR0.96712641
48PDGFRA0.96346474
49ICK0.94007209
50PBK0.92661868
51AKT20.92188453
52HIPK20.91716381
53SIK30.91651948
54NEK20.91459404
55TESK10.90931824
56CHEK10.90464558
57TAOK10.85235266
58EEF2K0.84870765
59FGFR30.84750673
60RPS6KB20.84365913
61AKT30.83035014
62MET0.78469505
63TAF10.77182870
64LRRK20.75201857
65PTK60.73912324
66ADRBK10.72028731
67TTN0.70082944
68CDK40.69741193
69BMX0.69326860
70CAMK1D0.67400925
71CDK90.65117658
72DMPK0.65076714
73CDK80.64827006
74PAK60.64759041
75MAP2K60.64419540
76CDK20.63796150
77CAMK1G0.62420163
78VRK20.62314834
79STK380.62215550
80TSSK60.61691836
81WEE10.61450490
82MAPK120.59010795
83MARK10.58107388
84MAP3K130.55848682
85IRAK20.55713252
86MAP2K30.55635290
87RPS6KA20.55295534
88PTK20.54323747
89KSR10.53950044
90PRKD30.53745921
91PDPK10.52861543
92MAPK110.52677379
93LMTK20.52328763
94CSNK1E0.52289133
95DDR20.51772134
96PDK40.51719314
97PDK30.51719314
98MAP3K10.51484760
99MAP2K20.50201553
100ILK0.49407756
101CSK0.47877551
102UHMK10.47804776
103RET0.46440992
104TAOK20.46256972
105CAMKK10.45827329
106SIK20.45396677
107SIK10.42969627
108EPHA40.42764822
109PRKCI0.41960233
110ERBB40.41945014
111ERBB20.41190978
112MAPK100.40615009
113ATM0.39510846
114AURKA0.39499600
115MAPKAPK30.39096706
116PHKG20.38874124
117PHKG10.38874124
118SGK30.38643260
119KSR20.37657696
120MAP3K80.37269884
121CDK150.35112102
122CDK10.34627226
123SRPK10.34469303
124PAK10.33498291
125AURKB0.33166169
126DAPK10.32269044
127CDK11A0.32141114
128PAK20.31848839
129SCYL20.31257475
130GSK3B0.30841318
131CDK180.29723026
132MAPK140.28092733
133PRKAA10.26139901
134MAPK10.26008378
135RPS6KA30.24659434
136PAK30.23765899
137FLT30.23547963
138LATS10.23485636
139CSNK1D0.22620408
140CDK140.22039694
141BUB10.21944156
142BRD40.20250803
143ATR0.20078655
144PRKACG0.19888198
145IGF1R0.19265823

Predicted pathways (KEGG)

RankGene SetZ-score
1Vitamin B6 metabolism_Homo sapiens_hsa007504.47060229
2Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006034.23686033
3Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.59893785
4Fructose and mannose metabolism_Homo sapiens_hsa000513.48443993
5Galactose metabolism_Homo sapiens_hsa000522.35324658
6mTOR signaling pathway_Homo sapiens_hsa041502.17569549
7RNA transport_Homo sapiens_hsa030132.10854189
8Chronic myeloid leukemia_Homo sapiens_hsa052202.08245207
92-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.95599797
10Thyroid cancer_Homo sapiens_hsa052161.83344072
11Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.81220019
12mRNA surveillance pathway_Homo sapiens_hsa030151.80327230
13One carbon pool by folate_Homo sapiens_hsa006701.79831369
14Glycolysis / Gluconeogenesis_Homo sapiens_hsa000101.60479760
15Central carbon metabolism in cancer_Homo sapiens_hsa052301.52152173
16Prion diseases_Homo sapiens_hsa050201.51161192
17DNA replication_Homo sapiens_hsa030301.50561407
18Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.50033330
19Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.48775615
20Pancreatic cancer_Homo sapiens_hsa052121.48288638
21Biosynthesis of amino acids_Homo sapiens_hsa012301.47758904
22Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.46640988
23ErbB signaling pathway_Homo sapiens_hsa040121.45111689
24Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.37897506
25Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.35148629
26Mismatch repair_Homo sapiens_hsa034301.32016083
27Renal cell carcinoma_Homo sapiens_hsa052111.29351067
28Carbon metabolism_Homo sapiens_hsa012001.28429289
29Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.24206245
30Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.21707915
31Cell cycle_Homo sapiens_hsa041101.20713254
32Nitrogen metabolism_Homo sapiens_hsa009101.20473632
33Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.19439848
34Thyroid hormone signaling pathway_Homo sapiens_hsa049191.18335669
35Basal cell carcinoma_Homo sapiens_hsa052171.17804273
36Arachidonic acid metabolism_Homo sapiens_hsa005901.12128806
37Pentose and glucuronate interconversions_Homo sapiens_hsa000401.11096440
38Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.07957248
39Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.07646504
40Estrogen signaling pathway_Homo sapiens_hsa049151.06726736
41Longevity regulating pathway - multiple species_Homo sapiens_hsa042131.05986713
42Hippo signaling pathway_Homo sapiens_hsa043901.05081940
43Other types of O-glycan biosynthesis_Homo sapiens_hsa005141.04621147
44Spliceosome_Homo sapiens_hsa030401.04447179
45* Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.04340094
46Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.03310272
47Prostate cancer_Homo sapiens_hsa052150.99132721
48Non-small cell lung cancer_Homo sapiens_hsa052230.98640336
49Bladder cancer_Homo sapiens_hsa052190.98215988
50MicroRNAs in cancer_Homo sapiens_hsa052060.97604794
51Other glycan degradation_Homo sapiens_hsa005110.95046171
52Phospholipase D signaling pathway_Homo sapiens_hsa040720.93770798
53alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.91268168
54Hedgehog signaling pathway_Homo sapiens_hsa043400.90604432
55Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.90554746
56Melanogenesis_Homo sapiens_hsa049160.90295736
57Linoleic acid metabolism_Homo sapiens_hsa005910.88989180
58AMPK signaling pathway_Homo sapiens_hsa041520.88392693
59Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.86666612
60Lysine degradation_Homo sapiens_hsa003100.86466276
61Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.84965430
62Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.83410885
63RNA degradation_Homo sapiens_hsa030180.82038815
64Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.81786583
65Regulation of actin cytoskeleton_Homo sapiens_hsa048100.81361686
66Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.81214077
67Acute myeloid leukemia_Homo sapiens_hsa052210.80988178
68Cyanoamino acid metabolism_Homo sapiens_hsa004600.80410245
69Notch signaling pathway_Homo sapiens_hsa043300.79228412
70Inositol phosphate metabolism_Homo sapiens_hsa005620.77873831
71Transcriptional misregulation in cancer_Homo sapiens_hsa052020.77342021
72Synaptic vesicle cycle_Homo sapiens_hsa047210.75765600
73Pentose phosphate pathway_Homo sapiens_hsa000300.75715148
74VEGF signaling pathway_Homo sapiens_hsa043700.75220692
75Proteoglycans in cancer_Homo sapiens_hsa052050.74987169
76Vibrio cholerae infection_Homo sapiens_hsa051100.74861538
77Rap1 signaling pathway_Homo sapiens_hsa040150.74344466
78Fanconi anemia pathway_Homo sapiens_hsa034600.73738729
79Glucagon signaling pathway_Homo sapiens_hsa049220.72114302
80Pathways in cancer_Homo sapiens_hsa052000.71968135
81N-Glycan biosynthesis_Homo sapiens_hsa005100.71731572
82AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.71363817
83Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.69820809
84Tight junction_Homo sapiens_hsa045300.69240295
85Axon guidance_Homo sapiens_hsa043600.68215050
86Base excision repair_Homo sapiens_hsa034100.68198484
87Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.67730764
88Choline metabolism in cancer_Homo sapiens_hsa052310.66826008
89Dilated cardiomyopathy_Homo sapiens_hsa054140.66824155
90Melanoma_Homo sapiens_hsa052180.65546425
91Longevity regulating pathway - mammal_Homo sapiens_hsa042110.64406103
92Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.64197328
93Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.62905832
94Adherens junction_Homo sapiens_hsa045200.62057414
95Selenocompound metabolism_Homo sapiens_hsa004500.61199044
96Arginine biosynthesis_Homo sapiens_hsa002200.61010188
97Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.60065249
98Oocyte meiosis_Homo sapiens_hsa041140.59923369
99Arginine and proline metabolism_Homo sapiens_hsa003300.59916648
100Prolactin signaling pathway_Homo sapiens_hsa049170.59458708
101Sulfur relay system_Homo sapiens_hsa041220.59403131
102Wnt signaling pathway_Homo sapiens_hsa043100.58568321
103Cysteine and methionine metabolism_Homo sapiens_hsa002700.58400837
104p53 signaling pathway_Homo sapiens_hsa041150.58135316
105Sphingolipid signaling pathway_Homo sapiens_hsa040710.57491177
106Gap junction_Homo sapiens_hsa045400.56349316
107Colorectal cancer_Homo sapiens_hsa052100.55790870
108Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.54853985
109Endocytosis_Homo sapiens_hsa041440.54433723
110Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.54107250
111Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.53855159
112Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.52955014
113Phosphatidylinositol signaling system_Homo sapiens_hsa040700.52939489
114Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.50580909
115Thyroid hormone synthesis_Homo sapiens_hsa049180.50514832
116Bile secretion_Homo sapiens_hsa049760.50293298
117Tryptophan metabolism_Homo sapiens_hsa003800.50284188
118GnRH signaling pathway_Homo sapiens_hsa049120.50127171
119Aldosterone synthesis and secretion_Homo sapiens_hsa049250.49875026
120Hepatitis B_Homo sapiens_hsa051610.49062090
121Insulin resistance_Homo sapiens_hsa049310.48826626
122Long-term potentiation_Homo sapiens_hsa047200.48068558
123Neurotrophin signaling pathway_Homo sapiens_hsa047220.47577906
124Endometrial cancer_Homo sapiens_hsa052130.44185849
125Ovarian steroidogenesis_Homo sapiens_hsa049130.43921553
126HTLV-I infection_Homo sapiens_hsa051660.41499435
127Glioma_Homo sapiens_hsa052140.40768511
128Homologous recombination_Homo sapiens_hsa034400.40296686
129Adipocytokine signaling pathway_Homo sapiens_hsa049200.39901296
130Small cell lung cancer_Homo sapiens_hsa052220.38082394
131HIF-1 signaling pathway_Homo sapiens_hsa040660.37049500
132Chemical carcinogenesis_Homo sapiens_hsa052040.34847237
133Oxytocin signaling pathway_Homo sapiens_hsa049210.33128563
134Insulin signaling pathway_Homo sapiens_hsa049100.31459326
135Focal adhesion_Homo sapiens_hsa045100.31195395

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