UBXN10

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1sperm-egg recognition (GO:0035036)9.73371528
2acrosome assembly (GO:0001675)9.62281524
3epithelial cilium movement (GO:0003351)9.51098844
4cell wall macromolecule catabolic process (GO:0016998)9.19087315
5cell wall macromolecule metabolic process (GO:0044036)9.19087315
6multicellular organism reproduction (GO:0032504)9.02643666
7motile cilium assembly (GO:0044458)9.01840469
8binding of sperm to zona pellucida (GO:0007339)8.95367023
9spermatid development (GO:0007286)8.86410322
10cell-cell recognition (GO:0009988)8.64747202
11cilium movement (GO:0003341)8.63831470
12plasma membrane fusion (GO:0045026)8.41294645
13regulation of cilium movement (GO:0003352)8.33719714
14epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)7.96381601
15piRNA metabolic process (GO:0034587)7.88853465
16reproduction (GO:0000003)7.73457646
17primary alcohol catabolic process (GO:0034310)7.69012578
18negative regulation of inclusion body assembly (GO:0090084)7.22512969
19male meiosis (GO:0007140)7.06370854
20synaptonemal complex organization (GO:0070193)7.04830631
21vitamin transmembrane transport (GO:0035461)6.79519175
22ethanol metabolic process (GO:0006067)6.59261303
23synaptonemal complex assembly (GO:0007130)6.58564429
24microtubule bundle formation (GO:0001578)6.56208013
25single fertilization (GO:0007338)6.46921276
26diterpenoid biosynthetic process (GO:0016102)6.27082069
27sperm capacitation (GO:0048240)6.15091177
28spermatogenesis (GO:0007283)5.91611811
29male gamete generation (GO:0048232)5.89041051
30organic cation transport (GO:0015695)5.85571078
31regulation of inclusion body assembly (GO:0090083)5.79078765
32fertilization (GO:0009566)5.73708281
33regulation of microtubule-based movement (GO:0060632)5.66520337
34gamete generation (GO:0007276)5.41278378
35ventricular system development (GO:0021591)5.32100890
36left/right pattern formation (GO:0060972)5.27147458
37response to xenobiotic stimulus (GO:0009410)5.26306736
38pyrimidine-containing compound transmembrane transport (GO:0072531)5.19927657
39calcium ion-dependent exocytosis (GO:0017156)5.19343320
40ethanol oxidation (GO:0006069)5.18153941
41centriole assembly (GO:0098534)5.18098849
42male meiosis I (GO:0007141)5.17242650
43one-carbon compound transport (GO:0019755)5.11949447
44germ cell development (GO:0007281)5.09445264
45DNA methylation involved in gamete generation (GO:0043046)4.98714563
46tolerance induction (GO:0002507)4.91261086
47cellular process involved in reproduction in multicellular organism (GO:0022412)4.87929700
48lung epithelium development (GO:0060428)4.86745304
49negative regulation of toll-like receptor 4 signaling pathway (GO:0034144)4.63268708
50regulation of interleukin-5 production (GO:0032674)4.62927907
51seminiferous tubule development (GO:0072520)4.59207361
52negative regulation of immunoglobulin mediated immune response (GO:0002890)4.55749603
53negative regulation of B cell mediated immunity (GO:0002713)4.55749603
54glomerular epithelial cell development (GO:0072310)4.51702550
55negative regulation of humoral immune response (GO:0002921)4.51560955
56negative regulation of T cell differentiation in thymus (GO:0033085)4.47929516
57microtubule depolymerization (GO:0007019)4.47396539
58terpenoid biosynthetic process (GO:0016114)4.46512695
59establishment of apical/basal cell polarity (GO:0035089)4.43783928
60retinoic acid metabolic process (GO:0042573)4.27358692
61multicellular organismal reproductive process (GO:0048609)4.27167691
62chromosome organization involved in meiosis (GO:0070192)4.26907295
63cell projection assembly (GO:0030031)4.19996690
64meiosis I (GO:0007127)4.19617217
65regulation of interleukin-13 production (GO:0032656)4.17685971
66meiotic nuclear division (GO:0007126)4.12964554
67lactate metabolic process (GO:0006089)4.12471938
68intraciliary transport (GO:0042073)4.10242110
69genitalia morphogenesis (GO:0035112)4.10135983
70glycerol ether metabolic process (GO:0006662)4.10110432
71cell recognition (GO:0008037)4.05733999
72regulation of germinal center formation (GO:0002634)3.93504391
73positive regulation of tolerance induction (GO:0002645)3.92005048
74microtubule severing (GO:0051013)3.89937976
75establishment or maintenance of monopolar cell polarity (GO:0061339)3.84190558
76establishment of monopolar cell polarity (GO:0061162)3.84190558
77axoneme assembly (GO:0035082)3.81831116
78ether metabolic process (GO:0018904)3.77444800
79cytoplasmic microtubule organization (GO:0031122)3.74743813
80exogenous drug catabolic process (GO:0042738)3.65907455
81lateral ventricle development (GO:0021670)3.62582875
82protein refolding (GO:0042026)3.60223333
83protein localization to cilium (GO:0061512)3.58810204
84primary alcohol metabolic process (GO:0034308)3.51283076
85chromosome condensation (GO:0030261)3.50528454
86meiotic cell cycle (GO:0051321)3.49831372
87amino-acid betaine transport (GO:0015838)3.49271916
88carnitine transport (GO:0015879)3.49271916
89microtubule polymerization or depolymerization (GO:0031109)3.45855826
90DNA packaging (GO:0006323)3.44209738
91cilium organization (GO:0044782)3.41655731
92multicellular organismal development (GO:0007275)3.39391169
93carnitine transmembrane transport (GO:1902603)3.38930807
94retinol metabolic process (GO:0042572)3.37594142
95protein polyglutamylation (GO:0018095)3.34365867
96O-glycan processing (GO:0016266)3.32872737
97cilium assembly (GO:0042384)3.28684740
98cilium morphogenesis (GO:0060271)3.25450820
99sexual reproduction (GO:0019953)3.21306580
100spermatid nucleus differentiation (GO:0007289)3.19402731
101chaperone-mediated protein complex assembly (GO:0051131)3.18639428
102glutathione derivative biosynthetic process (GO:1901687)3.18029187
103glutathione derivative metabolic process (GO:1901685)3.18029187
104microtubule-based movement (GO:0007018)3.17058749
105establishment of tissue polarity (GO:0007164)3.14380708
106establishment of planar polarity (GO:0001736)3.14380708
107nucleoside diphosphate catabolic process (GO:0009134)3.08677106
108aldehyde catabolic process (GO:0046185)3.02235133
109hydrogen peroxide biosynthetic process (GO:0050665)3.01443734
110positive regulation of smoothened signaling pathway (GO:0045880)2.99524192
111cellular component assembly involved in morphogenesis (GO:0010927)2.98125913
112gene silencing by RNA (GO:0031047)2.97849581
113retinal rod cell development (GO:0046548)2.96992940
114determination of left/right symmetry (GO:0007368)2.94611216
115centriole replication (GO:0007099)2.93417783
116drug catabolic process (GO:0042737)2.92119586
117polyol catabolic process (GO:0046174)2.91613669
118nucleoside diphosphate phosphorylation (GO:0006165)2.91040807
119regulation of tolerance induction (GO:0002643)2.88840633
120regulation of cilium assembly (GO:1902017)2.86463062
121determination of bilateral symmetry (GO:0009855)2.86405788
122apical protein localization (GO:0045176)2.84764564
123multicellular organismal water homeostasis (GO:0050891)2.83281643
124carnitine metabolic process (GO:0009437)2.81475793
125regulation of autophagic vacuole assembly (GO:2000785)2.80587594
126regulation of microtubule depolymerization (GO:0031114)2.79752422
127specification of symmetry (GO:0009799)2.79610950
128microtubule-based process (GO:0007017)2.79153977
129left/right axis specification (GO:0070986)2.78953107
130COPI coating of Golgi vesicle (GO:0048205)2.76343177
131Golgi transport vesicle coating (GO:0048200)2.76343177
132lateral sprouting from an epithelium (GO:0060601)2.75718639
133regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)2.75332558
134progesterone metabolic process (GO:0042448)2.75246153
135glycolytic process (GO:0006096)2.72669565
136smoothened signaling pathway (GO:0007224)2.72640892
137phospholipase C-activating dopamine receptor signaling pathway (GO:0060158)2.69130735
138alditol metabolic process (GO:0019400)2.67703578
139reactive oxygen species biosynthetic process (GO:1903409)2.65897673
140gas transport (GO:0015669)2.64060700
141negative regulation of organelle assembly (GO:1902116)2.63785865
142hydrogen peroxide catabolic process (GO:0042744)2.63734485
143excretion (GO:0007588)2.63533983
144RNA destabilization (GO:0050779)2.62973653
145endocrine pancreas development (GO:0031018)2.62656515
146calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules (GO:0016338)2.62057740
147cell redox homeostasis (GO:0045454)2.59617442
148interferon-gamma secretion (GO:0072643)2.58897118
149organelle assembly (GO:0070925)2.58220026
150macroautophagy (GO:0016236)2.57736976
151oocyte development (GO:0048599)2.56099188
152phosphatidylcholine biosynthetic process (GO:0006656)2.55708905
153CDP-diacylglycerol biosynthetic process (GO:0016024)2.54016151
154sodium ion homeostasis (GO:0055078)2.52227386
155regulation of response to osmotic stress (GO:0047484)2.51756695
156quaternary ammonium group transport (GO:0015697)2.51560651
157iron ion import (GO:0097286)2.49666473
158regulation of spindle checkpoint (GO:0090231)2.49263061
159positive regulation of glycolytic process (GO:0045821)2.49046060
160RNA localization (GO:0006403)2.46911420
161meiotic cell cycle process (GO:1903046)2.45084565
162regulation of meiosis I (GO:0060631)2.44855914
163water homeostasis (GO:0030104)2.43869582
164regulation of protein kinase C signaling (GO:0090036)2.43566290
165peptidyl-glutamic acid modification (GO:0018200)2.42986988
166protein O-linked glycosylation (GO:0006493)2.40702464
167regulation of vacuole organization (GO:0044088)2.40684584
168oligosaccharide biosynthetic process (GO:0009312)2.40633178
169peptide hormone processing (GO:0016486)2.40471604
170GTP biosynthetic process (GO:0006183)2.39674079
171regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator 2.37272192
172sperm motility (GO:0030317)12.0541468
173fusion of sperm to egg plasma membrane (GO:0007342)11.0588819
174axonemal dynein complex assembly (GO:0070286)10.7217909
175cilium or flagellum-dependent cell motility (GO:0001539)10.4596711
176acrosome reaction (GO:0007340)10.3798113

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse8.49211504
2EZH2_22144423_ChIP-Seq_EOC_Human4.85905623
3TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse4.41801023
4DROSHA_22980978_ChIP-Seq_HELA_Human3.47094770
5TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse3.27815101
6* FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human3.24543824
7STAT6_21828071_ChIP-Seq_BEAS2B_Human3.10814124
8PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse2.93812290
9GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.63534538
10BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse2.54810293
11VDR_22108803_ChIP-Seq_LS180_Human2.48987156
12TRIM28_21343339_ChIP-Seq_HEK293_Human2.45798086
13ZNF274_21170338_ChIP-Seq_K562_Hela2.31340280
14DMRT1_21621532_ChIP-ChIP_FETAL_Ovary2.26816883
15CREM_20920259_ChIP-Seq_GC1-SPG_Mouse2.19709119
16ESR1_20079471_ChIP-ChIP_T-47D_Human2.13879359
17FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human2.06860595
18AHR_22903824_ChIP-Seq_MCF-7_Human2.01767774
19SOX2_27498859_Chip-Seq_STOMACH_Mouse1.94766403
20EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.92975716
21ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.88247805
22ESR1_21235772_ChIP-Seq_MCF-7_Human1.87074353
23TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.85449112
24PIAS1_25552417_ChIP-Seq_VCAP_Human1.85111127
25* RUNX1_27514584_Chip-Seq_MCF-7_Human1.80480753
26ESR2_21235772_ChIP-Seq_MCF-7_Human1.79844784
27GATA1_26923725_Chip-Seq_HPCs_Mouse1.79260654
28GATA1_19941826_ChIP-Seq_K562_Human1.76790331
29STAT1_20625510_ChIP-Seq_HELA_Human1.75803135
30AR_21915096_ChIP-Seq_LNCaP-1F5_Human1.75758692
31FOXM1_26456572_ChIP-Seq_MCF-7_Human1.74790249
32ARNT_22903824_ChIP-Seq_MCF-7_Human1.71057040
33TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.68420383
34ELK4_26923725_Chip-Seq_MESODERM_Mouse1.66639673
35* TP63_23658742_ChIP-Seq_EP156T_Human1.60660979
36* REST_21632747_ChIP-Seq_MESCs_Mouse1.58607896
37FLI1_27457419_Chip-Seq_LIVER_Mouse1.58458441
38CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.56480039
39WDR5_24793694_ChIP-Seq_LNCAP_Human1.55157568
40ZNF217_24962896_ChIP-Seq_MCF-7_Human1.53572947
41KLF5_25053715_ChIP-Seq_YYC3_Human1.50919943
42CDX2_20551321_ChIP-Seq_CACO-2_Human1.50847893
43TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.48893894
44MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.48354092
45* ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.47953750
46* SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.47249610
47SOX2_22085726_ChIP-Seq_NPCs_Mouse1.47120239
48TP63_22573176_ChIP-Seq_HFKS_Human1.46649697
49SOX2_20726797_ChIP-Seq_SW620_Human1.44464052
50FLI1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.44091747
51STAT1_17558387_ChIP-Seq_HELA_Human1.43622292
52* ETV1_20927104_ChIP-Seq_GIST48_Human1.42994999
53SOX9_24532713_ChIP-Seq_HFSC_Mouse1.42418732
54CTNNB1_20460455_ChIP-Seq_HCT116_Human1.41766554
55NR3C1_21868756_ChIP-Seq_MCF10A_Human1.40938378
56* FOXA1_25552417_ChIP-Seq_VCAP_Human1.40463963
57GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.39257657
58GATA3_21867929_ChIP-Seq_CD8_Mouse1.38482648
59KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.37618532
60P63_26484246_Chip-Seq_KERATINOCYTES_Human1.37316794
61* PCGF4_22325352_ChIP-Seq_293T-Rex_Human1.37107205
62ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.36478996
63FLI1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.35846141
64TDRD3_21172665_ChIP-Seq_MCF-7_Human1.34537811
65* PHF8_20622853_ChIP-Seq_HELA_Human1.34059850
66SMRT_27268052_Chip-Seq_Bcells_Human1.34039322
67SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.33929974
68TP53_18474530_ChIP-ChIP_U2OS_Human1.33806849
69STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.33041640
70PCGF2_27294783_Chip-Seq_ESCs_Mouse1.32531248
71PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.32170269
72* CDX2_21074721_ChIP-Seq_CACO-2_Mouse1.31843512
73RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.31769443
74TAL1_26923725_Chip-Seq_HPCs_Mouse1.30514964
75CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.29692980
76* HNFA_21074721_ChIP-Seq_CACO-2_Human1.29658948
77GATA2_21186366_ChIP-Seq_BM-HSCs_Mouse1.28714784
78CTBP2_25329375_ChIP-Seq_LNCAP_Human1.28396555
79FOXO3_23340844_ChIP-Seq_DLD1_Human1.27369471
80* KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.27263824
81EBNA1_20929547_Chip-Seq_RAJI-cells_Human1.26787285
82TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.25837811
83IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.23211894
84CBP_20019798_ChIP-Seq_JUKART_Human1.23211894
85* RBPJ_21746931_ChIP-Seq_IB4_Human1.22865519
86LUZP1_20508642_ChIP-Seq_ESCs_Mouse1.20400541
87YY1_22570637_ChIP-Seq_MALME-3M_Human1.20218750
88RUNX1_26923725_Chip-Seq_HPCs_Mouse1.19930751
89P53_21459846_ChIP-Seq_SAOS-2_Human1.19317965
90KDM2B_26808549_Chip-Seq_REH_Human1.18950115
91* FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human1.17203207
92GATA4_25053715_ChIP-Seq_YYC3_Human1.16345611
93FOXA2_19822575_ChIP-Seq_HepG2_Human1.15835410
94* RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.15402591
95* CBX2_22325352_ChIP-Seq_293T-Rex_Human1.14758245
96CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.14563533
97FLI1_21867929_ChIP-Seq_TH2_Mouse1.14551232
98RAD21_21589869_ChIP-Seq_MESCs_Mouse1.14130217
99TOP2B_26459242_ChIP-Seq_MCF-7_Human1.13934663
100NFIB_24661679_ChIP-Seq_LUNG_Mouse1.12366574
101ERG_20517297_ChIP-Seq_VCAP_Human1.12201029
102GF1_26923725_Chip-Seq_HPCs_Mouse1.11545392
103GATA3_24758297_ChIP-Seq_MCF-7_Human1.11134751
104* GATA2_19941826_ChIP-Seq_K562_Human1.10771984
105FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.09990401
106P68_20966046_ChIP-Seq_HELA_Human1.09886089
107* GATA6_21074721_ChIP-Seq_CACO-2_Human1.09383325
108CREB1_26743006_Chip-Seq_LNCaP_Human1.08920208
109SPI1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.08677254
110TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.08086515
111CEBPB_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.07999098
112* FOXA1_26743006_Chip-Seq_LNCaP-abl_Human1.07707536
113NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.06293489
114* NFYA_21822215_ChIP-Seq_K562_Human1.06164338
115* GATA6_21074721_ChIP-Seq_CACO-2_Mouse1.05655954
116PPARG_20176806_ChIP-Seq_3T3-L1_Mouse1.05378700
117SETDB1_19884257_ChIP-Seq_MESCs_Mouse1.05158535
118TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.03960718
119PHF8_20622854_ChIP-Seq_HELA_Human1.03843531
120CEBPB_22108803_ChIP-Seq_LS180_Human1.03651459
121SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.03600211
122EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.03085928
123LXR_22158963_ChIP-Seq_LIVER_Mouse1.02292263
124TET1_21451524_ChIP-Seq_MESCs_Mouse1.02260932
125NFE2_27457419_Chip-Seq_LIVER_Mouse1.02122637
126PPAR_26484153_Chip-Seq_NCI-H1993_Human1.00670142
127SMAD3_21741376_ChIP-Seq_HESCs_Human1.00399726
128MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.00173334
129SPI1_26923725_Chip-Seq_HPCs_Mouse0.99355332
130PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.99177898
131RARA_24833708_ChIP-Seq_LIVER_Mouse0.99101738
132PCGF2_27294783_Chip-Seq_NPCs_Mouse0.99072154
133CTCF_27219007_Chip-Seq_Bcells_Human0.98902081
134CTCF_20526341_ChIP-Seq_ESCs_Human0.98664352
135ZNF652_21678463_ChIP-ChIP_ZR75-1_Human0.98411424
136SMAD4_21799915_ChIP-Seq_A2780_Human0.98290880
137NANOG_18555785_Chip-Seq_ESCs_Mouse0.98286914
138ZNF263_19887448_ChIP-Seq_K562_Human0.98124562
139GATA3_21867929_ChIP-Seq_TH1_Mouse0.96797225
140CEBPB_26923725_Chip-Seq_MACROPHAGESS_Mouse0.96456834
141SMAD3_21741376_ChIP-Seq_ESCs_Human0.96112029
142TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.95579990
143CREB1_26743006_Chip-Seq_LNCaP-abl_Human0.95221320
144RACK7_27058665_Chip-Seq_MCF-7_Human0.95140049
145P300_27268052_Chip-Seq_Bcells_Human0.94957712
146MYC_27129775_Chip-Seq_CORNEA_Mouse0.94541026
147TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human0.94408514
148KAP1_22055183_ChIP-Seq_ESCs_Mouse0.94193828
149SUZ12_27294783_Chip-Seq_NPCs_Mouse0.92559323
150TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.92079446
151POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.92079446
152CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.92029115
153ESET_19884257_ChIP-Seq_ESCs_Mouse0.91761008
154RXRA_24833708_ChIP-Seq_LIVER_Mouse0.90884782
155AR_21572438_ChIP-Seq_LNCaP_Human0.90553198
156KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human0.90457365
157CRX_20693478_ChIP-Seq_RETINA_Mouse0.90393919
158BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.90164598
159SOX2_21211035_ChIP-Seq_LN229_Human0.89904809
160* NFYB_21822215_ChIP-Seq_K562_Human0.89374983
161CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.89098907
162CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse0.88745570
163ELF1_20517297_ChIP-Seq_JURKAT_Human0.88526050
164JARID1B-DAIN_22020125_ChIP-Seq_ESCs_Mouse0.87951257
165GF1B_26923725_Chip-Seq_HPCs_Mouse0.87814647
166NEUROD2_26341353_ChIP-Seq_CORTEX_Mouse0.87010129
167BCAT_22108803_ChIP-Seq_LS180_Human0.86252293
168* SMC4_20622854_ChIP-Seq_HELA_Human0.85811834
169P53_22387025_ChIP-Seq_ESCs_Mouse0.85634246
170SMAD4_19686287_ChIP-ChIP_HaCaT_Human0.85200466
171SOX11_22085726_ChIP-Seq_ESNs_Mouse0.85174779
172SMAD3_22036565_ChIP-Seq_ESCs_Mouse0.84833840
173GATA1_19941827_ChIP-Seq_MEL86_Mouse0.84186339
174CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons0.83742415
175RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human0.83475854
176* TBL1_22424771_ChIP-Seq_293T_Human0.83048359
177RCOR2_21632747_ChIP-Seq_MESCs_Mouse0.82529288
178STAT3_18555785_ChIP-Seq_MESCs_Mouse0.81958644
179SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.81934486
180FOXA1_27270436_Chip-Seq_PROSTATE_Human0.81679997

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002132_abnormal_respiratory_system5.84412573
2MP0003698_abnormal_male_reproductive5.06659002
3MP0001929_abnormal_gametogenesis4.66517499
4MP0008877_abnormal_DNA_methylation3.88667054
5MP0002277_abnormal_respiratory_mucosa3.57686230
6MP0008789_abnormal_olfactory_epithelium3.04870174
7MP0002210_abnormal_sex_determination2.82956863
8MP0003656_abnormal_erythrocyte_physiolo2.75280339
9MP0002653_abnormal_ependyma_morphology2.75091040
10MP0003283_abnormal_digestive_organ2.69976263
11MP0002161_abnormal_fertility/fecundity2.67942595
12MP0000013_abnormal_adipose_tissue2.64125866
13MP0004043_abnormal_pH_regulation2.62107362
14MP0005670_abnormal_white_adipose2.54147088
15MP0001145_abnormal_male_reproductive2.42685522
16MP0005083_abnormal_biliary_tract2.28036366
17MP0003878_abnormal_ear_physiology2.27562434
18MP0005377_hearing/vestibular/ear_phenot2.27562434
19MP0002909_abnormal_adrenal_gland2.25845330
20MP0000383_abnormal_hair_follicle2.19238212
21MP0000653_abnormal_sex_gland2.09113420
22MP0002693_abnormal_pancreas_physiology2.07183312
23MP0010678_abnormal_skin_adnexa2.03079402
24MP0005394_taste/olfaction_phenotype2.02142545
25MP0005499_abnormal_olfactory_system2.02142545
26MP0005410_abnormal_fertilization13.5558192
27MP0001765_abnormal_ion_homeostasis1.94866403
28MP0002877_abnormal_melanocyte_morpholog1.86098721
29MP0000678_abnormal_parathyroid_gland1.83127250
30MP0001944_abnormal_pancreas_morphology1.82257123
31MP0006072_abnormal_retinal_apoptosis1.67222935
32MP0001346_abnormal_lacrimal_gland1.66892843
33MP0010234_abnormal_vibrissa_follicle1.65279797
34MP0002837_dystrophic_cardiac_calcinosis1.55579332
35MP0005379_endocrine/exocrine_gland_phen1.46932369
36MP0010386_abnormal_urinary_bladder1.43313139
37MP0004264_abnormal_extraembryonic_tissu1.43253194
38MP0005248_abnormal_Harderian_gland1.34543939
39MP0002234_abnormal_pharynx_morphology1.32336791
40MP0005395_other_phenotype1.32216367
41MP0002160_abnormal_reproductive_system1.30219986
42MP0002249_abnormal_larynx_morphology1.26524504
43MP0008961_abnormal_basal_metabolism1.24827739
44MP0001986_abnormal_taste_sensitivity1.23157687
45MP0005165_increased_susceptibility_to1.22086662
46MP0003195_calcinosis1.12865172
47MP0004233_abnormal_muscle_weight1.11446449
48MP0002078_abnormal_glucose_homeostasis1.10112604
49MP0000569_abnormal_digit_pigmentation1.08445014
50MP0003183_abnormal_peptide_metabolism1.06561492
51MP0009780_abnormal_chondrocyte_physiolo1.06103519
52MP0001661_extended_life_span1.05136138
53MP0008995_early_reproductive_senescence1.04307047
54MP0005636_abnormal_mineral_homeostasis1.03238570
55MP0005085_abnormal_gallbladder_physiolo1.03235153
56MP0010155_abnormal_intestine_physiology1.03149052
57MP0002928_abnormal_bile_duct1.01547859
58MP0000003_abnormal_adipose_tissue1.00180118
59MP0002734_abnormal_mechanical_nocicepti0.99475063
60MP0009379_abnormal_foot_pigmentation0.98748519
61MP0000681_abnormal_thyroid_gland0.97581151
62MP0005220_abnormal_exocrine_pancreas0.97496856
63MP0000465_gastrointestinal_hemorrhage0.94931636
64MP0005666_abnormal_adipose_tissue0.94849249
65MP0005253_abnormal_eye_physiology0.92428531
66MP0005623_abnormal_meninges_morphology0.87906016
67MP0005164_abnormal_response_to0.86205144
68MP0003329_amyloid_beta_deposits0.86035160
69MP0001984_abnormal_olfaction0.85068400
70MP0002233_abnormal_nose_morphology0.84629453
71MP0002139_abnormal_hepatobiliary_system0.84333851
72MP0005408_hypopigmentation0.84276646
73MP0003646_muscle_fatigue0.83621669
74MP0000462_abnormal_digestive_system0.82911603
75MP0002735_abnormal_chemical_nociception0.80419257
76MP0000566_synostosis0.79893977
77MP0004883_abnormal_blood_vessel0.79767703
78MP0009046_muscle_twitch0.78771491
79MP0002136_abnormal_kidney_physiology0.78674684
80MP0001485_abnormal_pinna_reflex0.78428274
81MP0004270_analgesia0.78347151
82MP0005375_adipose_tissue_phenotype0.78205968
83MP0002282_abnormal_trachea_morphology0.78047340
84MP0002638_abnormal_pupillary_reflex0.77614012
85MP0010030_abnormal_orbit_morphology0.75718000
86MP0005389_reproductive_system_phenotype0.75151730
87MP0009765_abnormal_xenobiotic_induced0.75108109
88MP0003953_abnormal_hormone_level0.74064626
89MP0003303_peritoneal_inflammation0.73598522
90MP0003959_abnormal_lean_body0.66176787
91MP0003136_yellow_coat_color0.65981415
92MP0003115_abnormal_respiratory_system0.65341777
93MP0009643_abnormal_urine_homeostasis0.64203268
94MP0003453_abnormal_keratinocyte_physiol0.63485861
95MP0002295_abnormal_pulmonary_circulatio0.63072487
96MP0005257_abnormal_intraocular_pressure0.62553595
97MP0003172_abnormal_lysosome_physiology0.61886032
98MP0002405_respiratory_system_inflammati0.61513241
99MP0003787_abnormal_imprinting0.61490394
100MP0003879_abnormal_hair_cell0.61323349
101MP0002876_abnormal_thyroid_physiology0.60966496
102MP0009763_increased_sensitivity_to0.60384298
103MP0004133_heterotaxia0.60288621
104MP0005646_abnormal_pituitary_gland0.59555104
105MP0003075_altered_response_to0.57249816
106MP0005535_abnormal_body_temperature0.56652617
107MP0000358_abnormal_cell_content/0.56610272
108MP0009703_decreased_birth_body0.56553286
109MP0001666_abnormal_nutrient_absorption0.56504056
110MP0003122_maternal_imprinting0.56346054
111MP0002229_neurodegeneration0.55759941
112MP0005310_abnormal_salivary_gland0.54369712
113MP0003866_abnormal_defecation0.53872394
114MP0005365_abnormal_bile_salt0.53241743
115MP0002896_abnormal_bone_mineralization0.53181440
116MP0004019_abnormal_vitamin_homeostasis0.53021139
117MP0002098_abnormal_vibrissa_morphology0.51589727
118MP0006036_abnormal_mitochondrial_physio0.51522583
119MP0003119_abnormal_digestive_system0.50835980
120MP0000026_abnormal_inner_ear0.49736308
121MP0000467_abnormal_esophagus_morphology0.49494892
122MP0005645_abnormal_hypothalamus_physiol0.49053482
123MP0002133_abnormal_respiratory_system0.48787642
124MP0005388_respiratory_system_phenotype0.48787642
125MP0005391_vision/eye_phenotype0.48300586
126MP0000631_abnormal_neuroendocrine_gland0.48094523
127MP0003045_fibrosis0.47995603
128MP0005551_abnormal_eye_electrophysiolog0.46836535
129MP0001270_distended_abdomen0.46789986
130MP0001324_abnormal_eye_pigmentation0.46441004
131MP0001299_abnormal_eye_distance/0.46366214
132MP0006082_CNS_inflammation0.46309345
133MP0000534_abnormal_ureter_morphology0.44832192
134MP0004036_abnormal_muscle_relaxation0.44433302
135MP0002168_other_aberrant_phenotype0.43962497
136MP0004782_abnormal_surfactant_physiolog0.43946532
137MP0005174_abnormal_tail_pigmentation0.43496023
138MP0001664_abnormal_digestion0.42751218
139MP0001293_anophthalmia0.42344202
140MP0002084_abnormal_developmental_patter0.41243749
141MP0005503_abnormal_tendon_morphology0.40954161
142MP0002116_abnormal_craniofacial_bone0.40544000
143MP0001663_abnormal_digestive_system0.40354705
144MP0003942_abnormal_urinary_system0.40180972
145MP0002163_abnormal_gland_morphology0.40139133
146MP0002135_abnormal_kidney_morphology0.40134358
147MP0002971_abnormal_brown_adipose0.39648641
148MP0001756_abnormal_urination0.39302873
149MP0001963_abnormal_hearing_physiology0.39019011
150MP0002118_abnormal_lipid_homeostasis0.38209394
151MP0008875_abnormal_xenobiotic_pharmacok0.38183725
152MP0003300_gastrointestinal_ulcer0.38046168
153MP0001849_ear_inflammation0.37633115
154MP0002138_abnormal_hepatobiliary_system0.37271908
155MP0002177_abnormal_outer_ear0.36090741
156MP0000015_abnormal_ear_pigmentation0.35182366
157MP0002269_muscular_atrophy0.33592085
158MP0001502_abnormal_circadian_rhythm0.33123889
159MP0003633_abnormal_nervous_system0.31571714
160MP0005647_abnormal_sex_gland0.28634599

Predicted human phenotypes

RankGene SetZ-score
1Abnormal respiratory motile cilium physiology (HP:0012261)9.00072832
2Abnormal respiratory epithelium morphology (HP:0012253)8.24381650
3Abnormal respiratory motile cilium morphology (HP:0005938)8.24381650
4Chronic bronchitis (HP:0004469)7.83374353
5Rhinitis (HP:0012384)7.42892729
6Abnormal ciliary motility (HP:0012262)7.26232466
7Infertility (HP:0000789)6.17582879
8Nasal polyposis (HP:0100582)5.67728242
9Abnormality of the nasal mucosa (HP:0000433)4.80062741
10Bronchiectasis (HP:0002110)4.67691887
11Bronchitis (HP:0012387)4.51701911
12Nephronophthisis (HP:0000090)4.06079518
13Male infertility (HP:0003251)3.73471208
14Occipital encephalocele (HP:0002085)3.56146480
15Abnormality of the renal medulla (HP:0100957)3.18218677
16Chronic otitis media (HP:0000389)3.17243695
17Atelectasis (HP:0100750)3.09353793
18Hyperactive renin-angiotensin system (HP:0000841)3.05832118
19Abnormality of midbrain morphology (HP:0002418)2.96139927
20Molar tooth sign on MRI (HP:0002419)2.96139927
21Tubulointerstitial nephritis (HP:0001970)2.87781296
22Recurrent otitis media (HP:0000403)2.82987743
23Hyperinsulinemic hypoglycemia (HP:0000825)2.80682922
24Abnormal spermatogenesis (HP:0008669)2.51321927
25Recurrent sinusitis (HP:0011108)2.49644386
26Chronic hepatic failure (HP:0100626)2.44799050
27Tubular atrophy (HP:0000092)2.41138053
28Tubulointerstitial abnormality (HP:0001969)2.36383088
29Recurrent bronchitis (HP:0002837)2.30586949
30Medial flaring of the eyebrow (HP:0010747)2.22976481
31Abnormal drinking behavior (HP:0030082)2.20858135
32Polydipsia (HP:0001959)2.20858135
33Gonadotropin excess (HP:0000837)2.19952719
34Cystic liver disease (HP:0006706)2.15992466
35Hyperkalemia (HP:0002153)2.01617140
36Elevated circulating parathyroid hormone (PTH) level (HP:0003165)2.00623262
37Tubulointerstitial fibrosis (HP:0005576)2.00581403
38Abnormality of the renal cortex (HP:0011035)2.00270210
39Respiratory insufficiency due to defective ciliary clearance (HP:0200073)11.9562352
40Absent/shortened dynein arms (HP:0200106)11.4404371
41Dynein arm defect of respiratory motile cilia (HP:0012255)11.4404371
42Insulin-resistant diabetes mellitus (HP:0000831)1.98341919
43Congenital hepatic fibrosis (HP:0002612)1.94232368
44Stage 5 chronic kidney disease (HP:0003774)1.92436400
45Hypoglycemic seizures (HP:0002173)1.91010378
46Abnormality of renal excretion (HP:0011036)1.90182038
47Hypoplastic labia majora (HP:0000059)1.88085630
48Aplasia/Hypoplasia of the tongue (HP:0010295)1.87591058
49Anencephaly (HP:0002323)1.85556062
50Male pseudohermaphroditism (HP:0000037)1.84956214
51Renal salt wasting (HP:0000127)1.83571666
52Abnormal gallbladder physiology (HP:0012438)1.82947161
53Cholecystitis (HP:0001082)1.82947161
54Impulsivity (HP:0100710)1.80090594
55Absent frontal sinuses (HP:0002688)1.79903863
56Symptomatic seizures (HP:0011145)1.75693168
57Postaxial foot polydactyly (HP:0001830)1.75687078
58Retinal atrophy (HP:0001105)1.75261500
59Abnormality of the intrinsic pathway (HP:0010989)1.74964270
60Abnormality of the anterior horn cell (HP:0006802)1.73837067
61Degeneration of anterior horn cells (HP:0002398)1.73837067
62Asplenia (HP:0001746)1.70173727
63Pancreatic fibrosis (HP:0100732)1.70132518
64Asymmetric septal hypertrophy (HP:0001670)1.70112305
65Aplasia/Hypoplasia of the spleen (HP:0010451)1.69271319
66Abnormal urine output (HP:0012590)1.68177538
67Oculomotor apraxia (HP:0000657)1.68054944
68Abnormality of the labia majora (HP:0012881)1.67686970
69Congenital primary aphakia (HP:0007707)1.66309480
70Dyschromatopsia (HP:0007641)1.64956470
71Gait imbalance (HP:0002141)1.63933099
72Facial cleft (HP:0002006)1.61593342
73Furrowed tongue (HP:0000221)1.61285959
74Nephropathy (HP:0000112)1.60973399
75Neurofibrillary tangles (HP:0002185)1.60792666
76Bell-shaped thorax (HP:0001591)1.59913162
77Median cleft lip (HP:0000161)1.59356189
78Myoglobinuria (HP:0002913)1.58278974
79Hypoglycemic coma (HP:0001325)1.56586698
80Hyperparathyroidism (HP:0000843)1.56176522
81Abnormality of dentin (HP:0010299)1.54941386
82Decreased circulating renin level (HP:0003351)1.53167713
83Sclerocornea (HP:0000647)1.53126282
84Polyuria (HP:0000103)1.52448884
85Aplasia/Hypoplasia of the lens (HP:0008063)1.51959018
86Choroideremia (HP:0001139)1.51760714
87Truncal obesity (HP:0001956)1.50519386
88Azoospermia (HP:0000027)1.49837184
89Large for gestational age (HP:0001520)1.49659071
90Hyperphosphatemia (HP:0002905)1.49094593
91True hermaphroditism (HP:0010459)1.48275148
92Hyperaldosteronism (HP:0000859)1.48240891
93Abnormality of the dental root (HP:0006486)1.47591628
94Taurodontia (HP:0000679)1.47591628
95Abnormality of permanent molar morphology (HP:0011071)1.47591628
96Decreased central vision (HP:0007663)1.47164315
97Bundle branch block (HP:0011710)1.45722700
98Nephrogenic diabetes insipidus (HP:0009806)1.45267461
99EMG: neuropathic changes (HP:0003445)1.44838896
100Prolonged partial thromboplastin time (HP:0003645)1.44386055
101Chronic sinusitis (HP:0011109)1.44250672
102Abnormality of the dental pulp (HP:0006479)1.43056998
103Neoplasm of the heart (HP:0100544)1.42014251
104Postaxial hand polydactyly (HP:0001162)1.41453542
105Amyotrophic lateral sclerosis (HP:0007354)1.41215549
106Abnormality of renin-angiotensin system (HP:0000847)1.40649604
107Short thorax (HP:0010306)1.40551483
108Spastic tetraparesis (HP:0001285)1.39946950
109Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)1.38418974
110Pancreatic cysts (HP:0001737)1.37568474
111Short ribs (HP:0000773)1.37417955
112Abnormality of calcium-phosphate metabolism (HP:0100530)1.36113849
113Fibular hypoplasia (HP:0003038)1.35900470
114Abnormality of chloride homeostasis (HP:0011422)1.35332010
115Abnormality of the lower motor neuron (HP:0002366)1.35310420
116Type II lissencephaly (HP:0007260)1.35219448
117Late onset (HP:0003584)1.34993815
118Absent rod-and cone-mediated responses on ERG (HP:0007688)1.34975562
119Hemiparesis (HP:0001269)1.34621701
120Renal dysplasia (HP:0000110)1.34358356
121Abnormality of molar (HP:0011077)1.33331531
122Abnormality of molar morphology (HP:0011070)1.33331531
123Short nail (HP:0001799)1.25726974
124Glucose intolerance (HP:0000833)1.24592737
125Preaxial hand polydactyly (HP:0001177)1.23349968
126Hand muscle atrophy (HP:0009130)1.20352472
127Cone-rod dystrophy (HP:0000548)1.20078707
128Hypokalemic alkalosis (HP:0001949)1.19819397
129Hyponatremia (HP:0002902)1.19025621
130Abnormality of monocarboxylic acid metabolism (HP:0010996)1.16906251
131Poor coordination (HP:0002370)1.16358787
132Genital tract atresia (HP:0001827)1.15003856
133Bifid scrotum (HP:0000048)1.14375322
134Abnormality of the distal phalanges of the toes (HP:0010182)1.12136170
135Vaginal atresia (HP:0000148)1.11077035
136Aplasia/Hypoplasia involving the sinuses (HP:0009120)1.08946639
137Fetal akinesia sequence (HP:0001989)1.08850114
138Abnormality of the frontal sinuses (HP:0002687)1.08481465
139Obstructive sleep apnea (HP:0002870)1.08000824
140Spinal muscular atrophy (HP:0007269)1.03959924
141Lip pit (HP:0100267)1.01516976
142Popliteal pterygium (HP:0009756)0.97187136
143Cone-shaped epiphyses of the phalanges of the hand (HP:0010230)0.96262950
144Aplasia of the musculature (HP:0100854)0.94678457
145Flat acetabular roof (HP:0003180)0.94007540
146Abnormal rod and cone electroretinograms (HP:0008323)0.92957581
147Vascular calcification (HP:0004934)0.91805334
148Muscle fiber splitting (HP:0003555)0.91569817

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PDK46.99562824
2PDK36.99562824
3PRKD35.99944827
4TESK15.64965604
5PDK24.31898584
6ICK3.71598578
7MAPK153.65798413
8WNK43.00619764
9PASK2.73993553
10PNCK2.22312652
11NME12.17095744
12MAPKAPK32.02965844
13DYRK1B1.79794666
14SMG11.75793745
15STK241.75327624
16PTK2B1.70980942
17INSRR1.64086652
18EEF2K1.61787457
19BCR1.61332854
20STK381.60175861
21STK391.56704337
22MAP3K31.47228388
23MAP3K71.37600306
24LRRK21.35087758
25MST1R1.23363530
26STK161.23360509
27STK101.23202270
28EPHA31.20995006
29NEK21.20020509
30TRPM71.16968139
31WNK11.16382690
32TAOK31.12271936
33TAOK11.11293807
34WNK30.99235379
35IRAK10.98041554
36PDK10.93073351
37PTK60.84844170
38TLK10.78250349
39DYRK30.78029705
40MAP3K120.77012089
41MAP3K20.74942884
42PRKCI0.74678313
43TBK10.74354257
44ERBB20.72855537
45NTRK20.68855195
46TRIB30.66915480
47PDPK10.66774452
48ERBB30.64931363
49MST40.64703972
50HIPK20.61955275
51IRAK20.60785509
52CAMK1G0.60684236
53ERN10.59714904
54NLK0.59165965
55VRK10.57695107
56FLT30.53814997
57PINK10.53479112
58STK30.51781382
59SGK10.51670367
60FRK0.51494477
61TYRO30.50810207
62NTRK10.50313680
63FGFR30.50133192
64MAP3K40.48684620
65BRAF0.47322848
66PRKCQ0.46960185
67PRKAA20.45065353
68PRKCD0.42859837
69MAP3K10.41933564
70CAMK2G0.40324353
71AURKA0.40260633
72MTOR0.40073488
73CDC42BPA0.38957787
74MARK20.38774851
75MAP2K40.35856625
76BMPR1B0.35544219
77UHMK10.34602142
78RPS6KB20.33203757
79AKT30.33017911
80PRKAA10.32974323
81MET0.31955038
82TSSK60.31262282
83PTK20.30942560
84LMTK20.30085003
85OXSR10.28375933
86MUSK0.27497617
87TYK20.27035233
88STK38L0.26934167
89STK110.26398150
90CHEK10.25807100
91GRK60.25737781
92PDGFRB0.25385455
93CAMKK10.25165452
94ROCK20.24961165
95AKT20.23584757
96CAMKK20.23564068
97MAP2K60.23159483
98RIPK40.22997014
99CHEK20.22791206
100SGK4940.22286980
101SGK2230.22286980
102GSK3A0.22111198
103MATK0.21564578
104PRKCG0.20738609
105PLK10.20254109
106DYRK1A0.20198749
107NEK90.20084803
108ROCK10.20084188
109RET0.19725619
110SGK20.19028244
111LATS10.18990427
112PDGFRA0.18778439
113PAK40.18716758
114MAP2K70.18308910
115TTK0.18282395
116PAK20.18105971
117RIPK10.17755274
118FYN0.17489481
119ADRBK10.17174900
120ABL10.17089551
121ATM0.16832814
122PRKACG0.16623990
123SRC0.16288869
124ZAP700.16065299
125RPS6KB10.15795275
126NTRK30.15545745
127PRKCZ0.15489841
128PAK10.15090584
129PRKD20.14952097
130MAP3K80.14864484
131PBK0.14555854
132PRKDC0.14478058
133MAP2K20.14472731
134BRSK20.13097019
135MAPKAPK50.12494017
136EPHA40.12451083
137RPS6KA20.12420299
138NEK60.11988006
139FER0.11817951
140MARK30.11425501
141CCNB10.10062465
142MAPK100.09781782
143GSK3B0.08747069
144TIE10.08082762
145PRKACA0.07641375
146EPHB10.06375219
147GRK10.06177299
148PRKG10.05693218
149CDK90.05242432
150PAK30.05176099
151CSK0.03832102
152EPHA20.03589251
153ATR0.03283507
154RPS6KA30.03228453
155PRKCA0.02602327
156DAPK20.02354975
157EGFR0.01423201
158PRKCB0.01307641

Predicted pathways (KEGG)

RankGene SetZ-score
1Maturity onset diabetes of the young_Homo sapiens_hsa049505.15601417
2Chemical carcinogenesis_Homo sapiens_hsa052044.67526096
3Tyrosine metabolism_Homo sapiens_hsa003504.03836862
4Glycolysis / Gluconeogenesis_Homo sapiens_hsa000103.13697703
5beta-Alanine metabolism_Homo sapiens_hsa004103.12735207
6Protein processing in endoplasmic reticulum_Homo sapiens_hsa041413.11885782
7Carbohydrate digestion and absorption_Homo sapiens_hsa049732.77594576
8Glucagon signaling pathway_Homo sapiens_hsa049222.71615365
9Insulin secretion_Homo sapiens_hsa049112.66366661
10Retinol metabolism_Homo sapiens_hsa008302.52891434
11Pyruvate metabolism_Homo sapiens_hsa006202.50941049
12Caffeine metabolism_Homo sapiens_hsa002322.48454543
13Fatty acid biosynthesis_Homo sapiens_hsa000612.35654173
14Selenocompound metabolism_Homo sapiens_hsa004502.32179694
15alpha-Linolenic acid metabolism_Homo sapiens_hsa005922.22553205
16Protein export_Homo sapiens_hsa030602.22273208
17Vitamin B6 metabolism_Homo sapiens_hsa007502.19330754
18Linoleic acid metabolism_Homo sapiens_hsa005912.14442378
19Sulfur metabolism_Homo sapiens_hsa009202.02205222
20Dorso-ventral axis formation_Homo sapiens_hsa043201.95977387
21Propanoate metabolism_Homo sapiens_hsa006401.90851860
22Amphetamine addiction_Homo sapiens_hsa050311.87973865
23Glycosaminoglycan degradation_Homo sapiens_hsa005311.80986155
24Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.78464589
25Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.76894917
26Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.76479232
27Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.64369599
28Steroid hormone biosynthesis_Homo sapiens_hsa001401.61231838
29Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.59429025
30Fatty acid degradation_Homo sapiens_hsa000711.48030220
31Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.46690740
32Longevity regulating pathway - multiple species_Homo sapiens_hsa042131.40089770
33Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.36686880
34Tight junction_Homo sapiens_hsa045301.35073758
35Basal transcription factors_Homo sapiens_hsa030221.34420850
36Glycerolipid metabolism_Homo sapiens_hsa005611.30405803
37Renin secretion_Homo sapiens_hsa049241.29202552
38Type II diabetes mellitus_Homo sapiens_hsa049301.29164467
39N-Glycan biosynthesis_Homo sapiens_hsa005101.25262480
40Fructose and mannose metabolism_Homo sapiens_hsa000511.23627944
41Collecting duct acid secretion_Homo sapiens_hsa049661.23071116
42Fatty acid metabolism_Homo sapiens_hsa012121.19443462
43Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.15901412
44Fat digestion and absorption_Homo sapiens_hsa049751.15255103
45PPAR signaling pathway_Homo sapiens_hsa033201.13839014
46Peroxisome_Homo sapiens_hsa041461.12021486
47Vibrio cholerae infection_Homo sapiens_hsa051101.11123347
48Cocaine addiction_Homo sapiens_hsa050301.08758049
49Taste transduction_Homo sapiens_hsa047421.08294084
50Glycerophospholipid metabolism_Homo sapiens_hsa005641.08250445
51Thyroid hormone synthesis_Homo sapiens_hsa049181.05650653
52Mineral absorption_Homo sapiens_hsa049781.05422884
53Long-term potentiation_Homo sapiens_hsa047201.02173853
54Starch and sucrose metabolism_Homo sapiens_hsa005000.97019564
55Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.96568992
56Sphingolipid metabolism_Homo sapiens_hsa006000.93013785
57Pancreatic secretion_Homo sapiens_hsa049720.93009583
58Oocyte meiosis_Homo sapiens_hsa041140.92951910
59Ether lipid metabolism_Homo sapiens_hsa005650.90314831
60Histidine metabolism_Homo sapiens_hsa003400.89432313
61Adipocytokine signaling pathway_Homo sapiens_hsa049200.89416624
62Estrogen signaling pathway_Homo sapiens_hsa049150.89300728
63ABC transporters_Homo sapiens_hsa020100.89296298
64Huntingtons disease_Homo sapiens_hsa050160.88010430
65Hedgehog signaling pathway_Homo sapiens_hsa043400.87711706
66Drug metabolism - other enzymes_Homo sapiens_hsa009830.87365659
67cGMP-PKG signaling pathway_Homo sapiens_hsa040220.86085491
68Primary bile acid biosynthesis_Homo sapiens_hsa001200.83358688
69Complement and coagulation cascades_Homo sapiens_hsa046100.80090119
70Synaptic vesicle cycle_Homo sapiens_hsa047210.79546291
71Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.78260575
72Pentose phosphate pathway_Homo sapiens_hsa000300.78236445
73Type I diabetes mellitus_Homo sapiens_hsa049400.77407303
74Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.77205285
75Cardiac muscle contraction_Homo sapiens_hsa042600.77127159
76Antigen processing and presentation_Homo sapiens_hsa046120.73125182
77Insulin resistance_Homo sapiens_hsa049310.71777442
78Vascular smooth muscle contraction_Homo sapiens_hsa042700.70421443
79Carbon metabolism_Homo sapiens_hsa012000.68667137
80Other glycan degradation_Homo sapiens_hsa005110.66113537
81Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.63876194
82AMPK signaling pathway_Homo sapiens_hsa041520.63632502
83Hepatitis C_Homo sapiens_hsa051600.60947663
84Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.58378342
85Leukocyte transendothelial migration_Homo sapiens_hsa046700.57614569
86Purine metabolism_Homo sapiens_hsa002300.57608463
87Choline metabolism in cancer_Homo sapiens_hsa052310.57334511
88Aldosterone synthesis and secretion_Homo sapiens_hsa049250.57102990
89Notch signaling pathway_Homo sapiens_hsa043300.54759492
90Circadian entrainment_Homo sapiens_hsa047130.53651948
91Olfactory transduction_Homo sapiens_hsa047400.52803435
92Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.52305871
93Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.51921779
94Gastric acid secretion_Homo sapiens_hsa049710.51895583
95Protein digestion and absorption_Homo sapiens_hsa049740.50279451
96Adherens junction_Homo sapiens_hsa045200.49357416
97Alcoholism_Homo sapiens_hsa050340.48323524
98Inositol phosphate metabolism_Homo sapiens_hsa005620.45107435
99Lysosome_Homo sapiens_hsa041420.43488682
100Tryptophan metabolism_Homo sapiens_hsa003800.43029323
101Arachidonic acid metabolism_Homo sapiens_hsa005900.42772495
102Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.42540598
103Phosphatidylinositol signaling system_Homo sapiens_hsa040700.42525583
104Dopaminergic synapse_Homo sapiens_hsa047280.42242219
105Bile secretion_Homo sapiens_hsa049760.40489326
106Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.40474565
107Pentose and glucuronate interconversions_Homo sapiens_hsa000400.40017617
108Endocytosis_Homo sapiens_hsa041440.39187387
109Cysteine and methionine metabolism_Homo sapiens_hsa002700.39089790
110Glutathione metabolism_Homo sapiens_hsa004800.38660626
111cAMP signaling pathway_Homo sapiens_hsa040240.38184979
112Salivary secretion_Homo sapiens_hsa049700.37398641
113Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.36820390
114Arginine and proline metabolism_Homo sapiens_hsa003300.35984156
115Calcium signaling pathway_Homo sapiens_hsa040200.35602551
116Circadian rhythm_Homo sapiens_hsa047100.35418374
117Insulin signaling pathway_Homo sapiens_hsa049100.34338224
118Thyroid hormone signaling pathway_Homo sapiens_hsa049190.34248403
119Hematopoietic cell lineage_Homo sapiens_hsa046400.33523986
120Longevity regulating pathway - mammal_Homo sapiens_hsa042110.33471579
121mRNA surveillance pathway_Homo sapiens_hsa030150.33413012
122Nicotine addiction_Homo sapiens_hsa050330.33395207
123Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.30451284
124Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.30444873
125Butanoate metabolism_Homo sapiens_hsa006500.28552666
126Fanconi anemia pathway_Homo sapiens_hsa034600.28498568
127Central carbon metabolism in cancer_Homo sapiens_hsa052300.27290660
128Transcriptional misregulation in cancer_Homo sapiens_hsa052020.26823178
129Arginine biosynthesis_Homo sapiens_hsa002200.26513186
130Cyanoamino acid metabolism_Homo sapiens_hsa004600.26486845
131Vitamin digestion and absorption_Homo sapiens_hsa049770.25091741
132Metabolic pathways_Homo sapiens_hsa011000.24990280
133Phototransduction_Homo sapiens_hsa047440.23154806
134Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.23024536
135Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.22942877
136Basal cell carcinoma_Homo sapiens_hsa052170.22767805
137Phenylalanine metabolism_Homo sapiens_hsa003600.21475997
138Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.19021529
139Amoebiasis_Homo sapiens_hsa051460.18688828
140Serotonergic synapse_Homo sapiens_hsa047260.18572819
141Regulation of autophagy_Homo sapiens_hsa041400.16527056
142Sphingolipid signaling pathway_Homo sapiens_hsa040710.15223408
143Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.14255148
144Jak-STAT signaling pathway_Homo sapiens_hsa046300.13217340
145Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.12863948
146Hippo signaling pathway_Homo sapiens_hsa043900.10675935
147Ovarian steroidogenesis_Homo sapiens_hsa049130.09345685
148Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.08787269
149Nitrogen metabolism_Homo sapiens_hsa009100.07515580
150Prostate cancer_Homo sapiens_hsa052150.04984333
151Phagosome_Homo sapiens_hsa041450.04877196
152Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.03615660

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