UBXN2B

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1pyrimidine nucleobase catabolic process (GO:0006208)5.53677031
2neural tube formation (GO:0001841)5.41223068
3positive regulation of excitatory postsynaptic membrane potential (GO:2000463)4.91040269
4regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act4.85671226
5vocalization behavior (GO:0071625)4.68469051
6regulation of glutamate receptor signaling pathway (GO:1900449)4.59665871
7regulation of short-term neuronal synaptic plasticity (GO:0048172)4.57291225
8synaptic vesicle docking involved in exocytosis (GO:0016081)4.55991397
9DNA double-strand break processing (GO:0000729)4.44467477
10synaptic vesicle exocytosis (GO:0016079)4.40400696
11regulation of synaptic vesicle exocytosis (GO:2000300)4.40355259
12ionotropic glutamate receptor signaling pathway (GO:0035235)4.37965942
13synaptic vesicle maturation (GO:0016188)4.37672829
14neuron cell-cell adhesion (GO:0007158)4.36984571
15positive regulation of neurotransmitter secretion (GO:0001956)4.30359374
16nucleobase catabolic process (GO:0046113)4.28425525
17protein localization to synapse (GO:0035418)4.21551632
18locomotory exploration behavior (GO:0035641)4.21528348
19regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)4.20533350
20regulation of synaptic vesicle transport (GO:1902803)4.15263871
21synaptic transmission, glutamatergic (GO:0035249)4.14591176
22glutamate secretion (GO:0014047)4.09825321
23neuron-neuron synaptic transmission (GO:0007270)4.04412338
24positive regulation of neurotransmitter transport (GO:0051590)3.93024346
25negative regulation of translation involved in gene silencing by miRNA (GO:0035278)3.92920268
26negative regulation of translation, ncRNA-mediated (GO:0040033)3.92920268
27regulation of translation, ncRNA-mediated (GO:0045974)3.92920268
28postsynaptic membrane organization (GO:0001941)3.91813624
29neurotransmitter-gated ion channel clustering (GO:0072578)3.90056516
30glutamate receptor signaling pathway (GO:0007215)3.86521306
31neutrophil mediated immunity (GO:0002446)3.85398467
32positive regulation of calcium ion-dependent exocytosis (GO:0045956)3.83346640
33regulation of long-term neuronal synaptic plasticity (GO:0048169)3.75257781
34negative regulation of synaptic transmission, glutamatergic (GO:0051967)3.69429890
35positive regulation of membrane potential (GO:0045838)3.62471499
36presynaptic membrane assembly (GO:0097105)3.58601999
37neuronal action potential propagation (GO:0019227)3.56823328
38exploration behavior (GO:0035640)3.55159649
39olfactory bulb development (GO:0021772)3.52491265
40regulation of neuronal synaptic plasticity (GO:0048168)3.49654753
41nonmotile primary cilium assembly (GO:0035058)3.48297341
42polyketide metabolic process (GO:0030638)3.47253065
43doxorubicin metabolic process (GO:0044598)3.47253065
44daunorubicin metabolic process (GO:0044597)3.47253065
45startle response (GO:0001964)3.45519384
46neurotransmitter secretion (GO:0007269)3.41647172
47negative regulation of synaptic transmission, GABAergic (GO:0032229)3.41428321
48myeloid leukocyte mediated immunity (GO:0002444)3.40421402
49protein localization to cilium (GO:0061512)3.37976794
50regulation of synapse structural plasticity (GO:0051823)3.37443435
51long-term synaptic potentiation (GO:0060291)3.35598588
52regulation of excitatory postsynaptic membrane potential (GO:0060079)3.34021003
53regulation of neurotransmitter secretion (GO:0046928)3.33033132
54negative regulation of B cell mediated immunity (GO:0002713)3.29725704
55negative regulation of immunoglobulin mediated immune response (GO:0002890)3.29725704
56presynaptic membrane organization (GO:0097090)3.26849563
57regulation of synaptic transmission, glutamatergic (GO:0051966)3.25397465
58long-term memory (GO:0007616)3.23492000
59negative regulation of DNA recombination (GO:0045910)3.22236119
60limb bud formation (GO:0060174)3.20831114
61adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191)3.20454621
62regulation of neurotransmitter transport (GO:0051588)3.20065774
63positive regulation of synaptic transmission, GABAergic (GO:0032230)3.19437355
64regulation of respiratory system process (GO:0044065)3.18553908
65membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.18391756
66neuron recognition (GO:0008038)3.16159221
67gamma-aminobutyric acid signaling pathway (GO:0007214)3.15190360
68positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)3.14924532
69regulation of postsynaptic membrane potential (GO:0060078)3.13206674
70positive regulation of synaptic transmission, glutamatergic (GO:0051968)3.12328674
71regulation of respiratory gaseous exchange by neurological system process (GO:0002087)3.11929351
72leukocyte migration involved in inflammatory response (GO:0002523)3.10472946
73transmission of nerve impulse (GO:0019226)3.10237092
74striatum development (GO:0021756)3.09297674
75regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.07347666
76synaptic vesicle endocytosis (GO:0048488)3.05169728
77behavioral defense response (GO:0002209)3.02765157
78behavioral fear response (GO:0001662)3.02765157
79regulation of synaptic plasticity (GO:0048167)3.00400077
80G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.99476939
81histone mRNA catabolic process (GO:0071044)2.99128093
82G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)2.97873965
83innervation (GO:0060384)2.96137331
84mechanosensory behavior (GO:0007638)2.96054119
85negative regulation of DNA-dependent DNA replication (GO:2000104)2.95734094
86microglial cell activation (GO:0001774)2.95207387
87response to histamine (GO:0034776)2.93199323
88axonal fasciculation (GO:0007413)2.93027860
89detection of molecule of bacterial origin (GO:0032490)2.89669938
90modulation by organism of immune response of other organism involved in symbiotic interaction (GO:002.87537050
91modulation by organism of defense response of other organism involved in symbiotic interaction (GO:02.87537050
92positive regulation by organism of defense response of other organism involved in symbiotic interact2.87537050
93modulation by symbiont of host immune response (GO:0052553)2.87537050
94positive regulation by symbiont of host defense response (GO:0052509)2.87537050
95modulation by symbiont of host defense response (GO:0052031)2.87537050
96learning (GO:0007612)2.86558463
97regulation of catecholamine uptake involved in synaptic transmission (GO:0051940)2.86209418
98regulation of dopamine uptake involved in synaptic transmission (GO:0051584)2.86209418
99synaptic transmission, dopaminergic (GO:0001963)2.85044613
100retinal ganglion cell axon guidance (GO:0031290)2.84728464
101response to amphetamine (GO:0001975)2.80761673
102regulation of meiosis I (GO:0060631)2.77835107
103dendritic spine morphogenesis (GO:0060997)2.77250180
104positive regulation of synapse maturation (GO:0090129)2.76791133
105regulation of dendritic spine morphogenesis (GO:0061001)2.76442409
106neurotransmitter transport (GO:0006836)2.75934029
107regulation of synaptic transmission, GABAergic (GO:0032228)2.75734053
108regulation of neurotransmitter uptake (GO:0051580)2.75086203
109positive regulation of synaptic transmission (GO:0050806)2.75021886
110serotonin metabolic process (GO:0042428)2.74569883
111negative regulation of dendrite development (GO:2000171)2.73805687
112auditory behavior (GO:0031223)2.73728186
113regulation of respiratory gaseous exchange (GO:0043576)2.72768112
114fear response (GO:0042596)2.72181895
115positive regulation of oligodendrocyte differentiation (GO:0048714)2.71968374
116membrane hyperpolarization (GO:0060081)2.71939048
117dendrite development (GO:0016358)2.71912939
118protein K11-linked deubiquitination (GO:0035871)2.71525857
119regulation of alternative mRNA splicing, via spliceosome (GO:0000381)2.70730199
120positive regulation of mRNA processing (GO:0050685)2.70274718
121response to auditory stimulus (GO:0010996)2.69475217
122regulation of female receptivity (GO:0045924)2.69022072
123neutrophil activation (GO:0042119)2.68976415
124respiratory burst (GO:0045730)2.68847427
125regulation of Arp2/3 complex-mediated actin nucleation (GO:0034315)2.67739101
126dopamine receptor signaling pathway (GO:0007212)2.67379362
127activated T cell proliferation (GO:0050798)2.66305629
128membrane depolarization (GO:0051899)2.65255103
129synaptic transmission (GO:0007268)2.64478056
130positive regulation of dendritic spine morphogenesis (GO:0061003)2.63842287
131microtubule depolymerization (GO:0007019)2.63524129
132serotonin receptor signaling pathway (GO:0007210)2.63371563
133microtubule anchoring (GO:0034453)2.63321726
134regulation of MHC class II biosynthetic process (GO:0045346)2.63316145
135regulation of glutamate secretion (GO:0014048)2.62685649
136pantothenate metabolic process (GO:0015939)2.61447518
137synapse assembly (GO:0007416)2.59658251
138cerebral cortex radially oriented cell migration (GO:0021799)2.59650153
139neutrophil activation involved in immune response (GO:0002283)2.59073442
140visual learning (GO:0008542)2.59009676
141regulation of synaptic transmission (GO:0050804)2.58828940
142cAMP catabolic process (GO:0006198)2.58591630
143regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)2.58578231
144regulation of telomere maintenance (GO:0032204)2.57554858
145gamma-aminobutyric acid transport (GO:0015812)2.57179749
146sequestering of actin monomers (GO:0042989)2.56232664
147negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515)2.54241901
148cell wall macromolecule catabolic process (GO:0016998)2.53948265
149phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092)2.52602916
150histone mRNA metabolic process (GO:0008334)2.48415435
151regulation of B cell receptor signaling pathway (GO:0050855)2.47822958
152intraciliary transport (GO:0042073)2.47330560
153cellular extravasation (GO:0045123)2.46355708
154adaptation of signaling pathway (GO:0023058)2.43388149
155RNA destabilization (GO:0050779)2.40882967
156regulation of collateral sprouting (GO:0048670)2.40498048
157negative regulation of lymphocyte mediated immunity (GO:0002707)2.40161025
158regulation of interferon-beta biosynthetic process (GO:0045357)2.39376303
159regulation of feeding behavior (GO:0060259)2.38579994
160negative regulation of alpha-beta T cell differentiation (GO:0046639)2.38351329
161positive regulation of mRNA metabolic process (GO:1903313)2.37926457
162negative regulation of T-helper cell differentiation (GO:0045623)2.37897786
163negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371)2.37897786
164glial cell proliferation (GO:0014009)2.37869503
165positive regulation of microtubule polymerization or depolymerization (GO:0031112)2.37083349
166positive regulation of potassium ion transmembrane transporter activity (GO:1901018)2.36111863
167DNA demethylation (GO:0080111)2.36032897
168response to host immune response (GO:0052572)2.34587655
169response to immune response of other organism involved in symbiotic interaction (GO:0052564)2.34587655
170positive regulation of interleukin-8 biosynthetic process (GO:0045416)2.33595391
171acrosome assembly (GO:0001675)2.32531746
172regulation of cilium movement (GO:0003352)2.31926246
173mRNA splice site selection (GO:0006376)2.31786710
174negative regulation of adaptive immune response based on somatic recombination of immune receptors b2.31002172
175forebrain neuron differentiation (GO:0021879)2.30902741
176regulation of nitric-oxide synthase biosynthetic process (GO:0051769)2.29290450
177negative regulation of calcium ion-dependent exocytosis (GO:0045955)2.29103342
178central nervous system projection neuron axonogenesis (GO:0021952)2.28929379
179central nervous system neuron axonogenesis (GO:0021955)2.27399391
180cullin deneddylation (GO:0010388)2.26889605
181alkaloid metabolic process (GO:0009820)2.26359098
182sympathetic nervous system development (GO:0048485)2.25878427
183dendrite morphogenesis (GO:0048813)2.25435796
184layer formation in cerebral cortex (GO:0021819)2.24608190
185cilium morphogenesis (GO:0060271)2.23243859
186positive regulation of microtubule polymerization (GO:0031116)2.22899354
187establishment of mitochondrion localization (GO:0051654)2.22805458
188protein neddylation (GO:0045116)2.22794198
189negative regulation of leukocyte mediated cytotoxicity (GO:0001911)2.22693201
190negative regulation of cell killing (GO:0031342)2.22693201

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.96567371
2GBX2_23144817_ChIP-Seq_PC3_Human4.50725061
3SALL1_21062744_ChIP-ChIP_HESCs_Human3.12683724
4GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.89803513
5SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.60602983
6JARID2_20064375_ChIP-Seq_MESCs_Mouse2.58184973
7RBPJ_22232070_ChIP-Seq_NCS_Mouse2.53080771
8IGF1R_20145208_ChIP-Seq_DFB_Human2.39327544
9REST_21632747_ChIP-Seq_MESCs_Mouse2.35373967
10CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.33165491
11TAF15_26573619_Chip-Seq_HEK293_Human2.25760687
12ZFP57_27257070_Chip-Seq_ESCs_Mouse2.19454268
13SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.15005377
14FUS_26573619_Chip-Seq_HEK293_Human2.05498019
15EZH2_27304074_Chip-Seq_ESCs_Mouse2.04250299
16SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.03517961
17CTBP2_25329375_ChIP-Seq_LNCAP_Human2.02007127
18RARB_27405468_Chip-Seq_BRAIN_Mouse2.01384246
19POU3F2_20337985_ChIP-ChIP_501MEL_Human1.99374724
20GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.95870656
21JARID2_20075857_ChIP-Seq_MESCs_Mouse1.93797601
22REST_18959480_ChIP-ChIP_MESCs_Mouse1.93238996
23P300_19829295_ChIP-Seq_ESCs_Human1.93209462
24CTBP1_25329375_ChIP-Seq_LNCAP_Human1.91277080
25SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.90154181
26SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.90086274
27EZH2_18974828_ChIP-Seq_MESCs_Mouse1.88498730
28RNF2_18974828_ChIP-Seq_MESCs_Mouse1.88498730
29MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.85760067
30SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.81441146
31EED_16625203_ChIP-ChIP_MESCs_Mouse1.79760350
32AR_21572438_ChIP-Seq_LNCaP_Human1.74702996
33ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.74181156
34BMI1_23680149_ChIP-Seq_NPCS_Mouse1.70674877
35* SMAD4_21799915_ChIP-Seq_A2780_Human1.70448885
36SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.69210899
37MTF2_20144788_ChIP-Seq_MESCs_Mouse1.67000068
38NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.66541135
39EWS_26573619_Chip-Seq_HEK293_Human1.61931112
40IKZF1_21737484_ChIP-ChIP_HCT116_Human1.55547901
41EZH2_27294783_Chip-Seq_ESCs_Mouse1.53611802
42PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.53282607
43FLI1_27457419_Chip-Seq_LIVER_Mouse1.53021447
44RNF2_27304074_Chip-Seq_ESCs_Mouse1.52777899
45CBX2_27304074_Chip-Seq_ESCs_Mouse1.52218332
46IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.51610037
47CBP_20019798_ChIP-Seq_JUKART_Human1.51610037
48RNF2_27304074_Chip-Seq_NSC_Mouse1.50208092
49SUZ12_27294783_Chip-Seq_ESCs_Mouse1.49970978
50DROSHA_22980978_ChIP-Seq_HELA_Human1.44911425
51SMAD3_21741376_ChIP-Seq_EPCs_Human1.44078123
52EZH2_27294783_Chip-Seq_NPCs_Mouse1.43949385
53ELK1_19687146_ChIP-ChIP_HELA_Human1.42369801
54PCGF2_27294783_Chip-Seq_ESCs_Mouse1.41667930
55IRF8_21731497_ChIP-ChIP_J774_Mouse1.41518949
56OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.36608892
57PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.35542424
58STAT3_23295773_ChIP-Seq_U87_Human1.34545665
59TOP2B_26459242_ChIP-Seq_MCF-7_Human1.33714262
60TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.32857204
61NANOG_18555785_Chip-Seq_ESCs_Mouse1.31657969
62POU5F1_16153702_ChIP-ChIP_HESCs_Human1.31504499
63CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.30069861
64BCAT_22108803_ChIP-Seq_LS180_Human1.29170548
65HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.29161678
66ZNF274_21170338_ChIP-Seq_K562_Hela1.28727750
67FLI1_21867929_ChIP-Seq_TH2_Mouse1.28645675
68JUN_21703547_ChIP-Seq_K562_Human1.28274692
69CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.27646659
70E2F4_17652178_ChIP-ChIP_JURKAT_Human1.26392142
71TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.25974176
72TCF4_23295773_ChIP-Seq_U87_Human1.25549784
73WT1_19549856_ChIP-ChIP_CCG9911_Human1.24816389
74SOX9_26525672_Chip-Seq_HEART_Mouse1.24348582
75KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.23588672
76E2F1_18555785_Chip-Seq_ESCs_Mouse1.23378460
77KLF5_20875108_ChIP-Seq_MESCs_Mouse1.22495558
78* AR_25329375_ChIP-Seq_VCAP_Human1.22025681
79* P53_22387025_ChIP-Seq_ESCs_Mouse1.21909989
80CDX2_19796622_ChIP-Seq_MESCs_Mouse1.20931460
81SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.20132173
82RUNX1_17652178_ChIP-ChIP_JURKAT_Human1.19930861
83EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.19343218
84PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.18736732
85RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.18010793
86PCGF2_27294783_Chip-Seq_NPCs_Mouse1.17516032
87SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.17259651
88TCF4_22108803_ChIP-Seq_LS180_Human1.16580795
89CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.15857359
90* PIAS1_25552417_ChIP-Seq_VCAP_Human1.14753850
91CRX_20693478_ChIP-Seq_RETINA_Mouse1.14163073
92HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.13739852
93IRF1_19129219_ChIP-ChIP_H3396_Human1.13336462
94CMYC_18555785_Chip-Seq_ESCs_Mouse1.12578063
95GABP_17652178_ChIP-ChIP_JURKAT_Human1.12188023
96OCT4_21477851_ChIP-Seq_ESCs_Mouse1.11691983
97HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.11025563
98GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.10182924
99ER_23166858_ChIP-Seq_MCF-7_Human1.09874073
100NR3C1_21868756_ChIP-Seq_MCF10A_Human1.09793454
101* PRDM14_20953172_ChIP-Seq_ESCs_Human1.09724513
102PADI4_21655091_ChIP-ChIP_MCF-7_Human1.09484422
103* RUNX2_22187159_ChIP-Seq_PCA_Human1.08333134
104TAL1_26923725_Chip-Seq_HPCs_Mouse1.08159033
105PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.07631763
106SUZ12_18555785_Chip-Seq_ESCs_Mouse1.07238408
107SOX2_21211035_ChIP-Seq_LN229_Gbm1.07163683
108SOX2_19829295_ChIP-Seq_ESCs_Human1.05083700
109NANOG_19829295_ChIP-Seq_ESCs_Human1.05083700
110P53_22127205_ChIP-Seq_FIBROBLAST_Human1.04118216
111STAT3_18555785_Chip-Seq_ESCs_Mouse1.03939426
112EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.03781788
113RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.03248663
114KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.03215314
115SUZ12_27294783_Chip-Seq_NPCs_Mouse1.03082013
116VDR_22108803_ChIP-Seq_LS180_Human1.02930643
117* YAP1_20516196_ChIP-Seq_MESCs_Mouse1.02695482
118SOX2_18555785_Chip-Seq_ESCs_Mouse1.02202563
119* TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.02072957
120SALL4_22934838_ChIP-ChIP_CD34+_Human1.01109747
121NMYC_18555785_Chip-Seq_ESCs_Mouse1.00366347
122EST1_17652178_ChIP-ChIP_JURKAT_Human1.00299728
123CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.00150955
124TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse0.99981519
125P300_18555785_Chip-Seq_ESCs_Mouse0.99853902
126TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.99459521
127NFE2_27457419_Chip-Seq_LIVER_Mouse0.98954314
128FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse0.98323811
129THAP11_20581084_ChIP-Seq_MESCs_Mouse0.98283632
130MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.97835915
131TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.97334423
132POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.97334423
133MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.97292594
134UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.97223104
135SMAD_19615063_ChIP-ChIP_OVARY_Human0.97212817
136* AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.95446689
137RUNX1_27457419_Chip-Seq_LIVER_Mouse0.95005342

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity5.22259470
2MP0003880_abnormal_central_pattern4.77474238
3MP0003635_abnormal_synaptic_transmissio3.41992929
4MP0009745_abnormal_behavioral_response2.96118147
5MP0002063_abnormal_learning/memory/cond2.88568247
6MP0001968_abnormal_touch/_nociception2.77927360
7MP0003724_increased_susceptibility_to2.75522184
8MP0002822_catalepsy2.61253695
9MP0001188_hyperpigmentation2.59927129
10MP0005248_abnormal_Harderian_gland2.57829614
11MP0003787_abnormal_imprinting2.56706275
12MP0005646_abnormal_pituitary_gland2.56667350
13MP0002572_abnormal_emotion/affect_behav2.55137574
14MP0002064_seizures2.49861848
15MP0004270_analgesia2.47469348
16MP0009046_muscle_twitch2.45801912
17MP0005423_abnormal_somatic_nervous2.44483332
18MP0005645_abnormal_hypothalamus_physiol2.44363370
19MP0002736_abnormal_nociception_after2.41733708
20MP0001486_abnormal_startle_reflex2.34754144
21MP0001529_abnormal_vocalization2.28876411
22MP0002272_abnormal_nervous_system2.20184069
23MP0002735_abnormal_chemical_nociception2.09356894
24MP0002734_abnormal_mechanical_nocicepti1.96531721
25MP0006292_abnormal_olfactory_placode1.95171701
26MP0008057_abnormal_DNA_replication1.86272683
27MP0003890_abnormal_embryonic-extraembry1.86124100
28MP0008877_abnormal_DNA_methylation1.84439683
29MP0002067_abnormal_sensory_capabilities1.82772208
30MP0003122_maternal_imprinting1.79163728
31MP0002184_abnormal_innervation1.77937291
32MP0006276_abnormal_autonomic_nervous1.77371435
33MP0002557_abnormal_social/conspecific_i1.72580695
34MP0003221_abnormal_cardiomyocyte_apopto1.70428523
35MP0004924_abnormal_behavior1.64131299
36MP0005386_behavior/neurological_phenoty1.64131299
37MP0001984_abnormal_olfaction1.63435224
38MP0001501_abnormal_sleep_pattern1.63115144
39MP0005174_abnormal_tail_pigmentation1.61266673
40MP0004147_increased_porphyrin_level1.60452626
41MP0000778_abnormal_nervous_system1.60046169
42MP0003879_abnormal_hair_cell1.57903972
43MP0004811_abnormal_neuron_physiology1.49131294
44MP0003121_genomic_imprinting1.47329872
45MP0002638_abnormal_pupillary_reflex1.47286557
46MP0001970_abnormal_pain_threshold1.44652458
47MP0001440_abnormal_grooming_behavior1.43962105
48MP0000631_abnormal_neuroendocrine_gland1.43142187
49MP0008569_lethality_at_weaning1.42164991
50MP0002653_abnormal_ependyma_morphology1.41595720
51MP0003567_abnormal_fetal_cardiomyocyte1.40948965
52MP0000516_abnormal_urinary_system1.40508913
53MP0005367_renal/urinary_system_phenotyp1.40508913
54MP0003195_calcinosis1.38167041
55MP0000955_abnormal_spinal_cord1.35454750
56MP0001293_anophthalmia1.35077680
57MP0003123_paternal_imprinting1.31300611
58MP0002733_abnormal_thermal_nociception1.30018116
59MP0001905_abnormal_dopamine_level1.28116353
60MP0001986_abnormal_taste_sensitivity1.25303777
61MP0009780_abnormal_chondrocyte_physiolo1.24491398
62MP0002882_abnormal_neuron_morphology1.21350155
63MP0002234_abnormal_pharynx_morphology1.16943201
64MP0002066_abnormal_motor_capabilities/c1.15681271
65MP0002277_abnormal_respiratory_mucosa1.12657070
66MP0000015_abnormal_ear_pigmentation1.10391187
67MP0004142_abnormal_muscle_tone1.08521114
68MP0005499_abnormal_olfactory_system1.06878951
69MP0005394_taste/olfaction_phenotype1.06878951
70MP0005075_abnormal_melanosome_morpholog1.06675439
71MP0010386_abnormal_urinary_bladder1.05484452
72MP0001963_abnormal_hearing_physiology1.05369809
73MP0002152_abnormal_brain_morphology1.04302903
74MP0001485_abnormal_pinna_reflex1.04228808
75MP0002090_abnormal_vision1.01163120
76MP0004742_abnormal_vestibular_system0.99016940
77MP0002009_preneoplasia0.98739949
78MP0000427_abnormal_hair_cycle0.97503931
79MP0002102_abnormal_ear_morphology0.97382712
80MP0002909_abnormal_adrenal_gland0.97022713
81MP0001324_abnormal_eye_pigmentation0.95048964
82MP0001502_abnormal_circadian_rhythm0.94879532
83MP0005551_abnormal_eye_electrophysiolog0.94449187
84MP0004885_abnormal_endolymph0.93588481
85MP0002928_abnormal_bile_duct0.93441665
86MP0003183_abnormal_peptide_metabolism0.93051116
87MP0002751_abnormal_autonomic_nervous0.87191541
88MP0008872_abnormal_physiological_respon0.85353979
89MP0005171_absent_coat_pigmentation0.85179156
90MP0005379_endocrine/exocrine_gland_phen0.84856484
91MP0002752_abnormal_somatic_nervous0.84293407
92MP0003632_abnormal_nervous_system0.83710976
93MP0003938_abnormal_ear_development0.82826004
94MP0000026_abnormal_inner_ear0.82392094
95MP0009697_abnormal_copulation0.82275216
96MP0008058_abnormal_DNA_repair0.81997256
97MP0003119_abnormal_digestive_system0.81149038
98MP0002069_abnormal_eating/drinking_beha0.80368223
99MP0000647_abnormal_sebaceous_gland0.79036001
100MP0006035_abnormal_mitochondrial_morpho0.78972824
101MP0001286_abnormal_eye_development0.78290575
102MP0002876_abnormal_thyroid_physiology0.78216129
103MP0005409_darkened_coat_color0.77996076
104MP0002095_abnormal_skin_pigmentation0.77865278
105MP0002229_neurodegeneration0.76959197
106MP0004043_abnormal_pH_regulation0.76882294
107MP0001177_atelectasis0.76115595
108MP0004858_abnormal_nervous_system0.75772385
109MP0002132_abnormal_respiratory_system0.75608615
110MP0000465_gastrointestinal_hemorrhage0.74066639
111MP0005195_abnormal_posterior_eye0.73840368
112MP0004883_abnormal_blood_vessel0.72851321
113MP0000569_abnormal_digit_pigmentation0.72742263
114MP0009703_decreased_birth_body0.70688903
115MP0004484_altered_response_of0.70623049
116MP0005391_vision/eye_phenotype0.70255889
117MP0006072_abnormal_retinal_apoptosis0.69877959
118MP0004085_abnormal_heartbeat0.68730450
119MP0003690_abnormal_glial_cell0.68201347
120MP0003861_abnormal_nervous_system0.67060122
121MP0001664_abnormal_digestion0.66669870
122MP0000681_abnormal_thyroid_gland0.66199176
123MP0002163_abnormal_gland_morphology0.64540245
124MP0004215_abnormal_myocardial_fiber0.63656523
125MP0003633_abnormal_nervous_system0.63266450
126MP0008789_abnormal_olfactory_epithelium0.60177416
127MP0003631_nervous_system_phenotype0.58486146
128MP0010770_preweaning_lethality0.57601286
129MP0002082_postnatal_lethality0.57601286
130MP0005253_abnormal_eye_physiology0.57582537
131MP0000678_abnormal_parathyroid_gland0.56791847
132MP0010769_abnormal_survival0.55554874
133MP0010768_mortality/aging0.54745726
134MP0010094_abnormal_chromosome_stability0.54445897

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)6.41663827
2Epileptic encephalopathy (HP:0200134)4.42347320
3Myokymia (HP:0002411)4.30487951
4Febrile seizures (HP:0002373)4.29089311
5Focal seizures (HP:0007359)3.98679736
6Visual hallucinations (HP:0002367)3.57806840
7Atonic seizures (HP:0010819)3.44655311
8Hypochromic microcytic anemia (HP:0004840)3.33067702
9Abnormal hair whorl (HP:0010721)3.29408072
10Broad-based gait (HP:0002136)3.19257857
11Hyperventilation (HP:0002883)3.17333919
12Volvulus (HP:0002580)3.00551324
13Medial flaring of the eyebrow (HP:0010747)2.95486107
14Progressive cerebellar ataxia (HP:0002073)2.91833360
15Absence seizures (HP:0002121)2.90424352
16Gait imbalance (HP:0002141)2.89493749
17Papillary thyroid carcinoma (HP:0002895)2.87646750
18Amyotrophic lateral sclerosis (HP:0007354)2.79306032
19Protruding tongue (HP:0010808)2.77827331
20Aqueductal stenosis (HP:0002410)2.73086971
21Abnormality of the heme biosynthetic pathway (HP:0010472)2.71281931
22Nephrogenic diabetes insipidus (HP:0009806)2.68101608
23Dialeptic seizures (HP:0011146)2.63252890
24Anxiety (HP:0000739)2.63081734
25Gaze-evoked nystagmus (HP:0000640)2.61606385
26Congenital primary aphakia (HP:0007707)2.60908310
27Generalized tonic-clonic seizures (HP:0002069)2.57076963
28Poor eye contact (HP:0000817)2.56234206
29Optic neuritis (HP:0100653)2.54892208
30Retrobulbar optic neuritis (HP:0100654)2.54892208
31Progressive inability to walk (HP:0002505)2.47909592
32Intestinal atresia (HP:0011100)2.40300136
33Impaired vibration sensation in the lower limbs (HP:0002166)2.36690203
34Oligodactyly (hands) (HP:0001180)2.36223603
35Thyroid carcinoma (HP:0002890)2.33151738
36Genetic anticipation (HP:0003743)2.31786511
37Absent eyebrow (HP:0002223)2.31333152
38Truncal ataxia (HP:0002078)2.29632488
39Abnormal ciliary motility (HP:0012262)2.29422696
40Failure to thrive in infancy (HP:0001531)2.27703052
41Inappropriate behavior (HP:0000719)2.24450103
42Absent speech (HP:0001344)2.23128567
43Inability to walk (HP:0002540)2.22878582
44Medulloblastoma (HP:0002885)2.21096426
45Patchy hypopigmentation of hair (HP:0011365)2.20510382
46Orchitis (HP:0100796)2.19397672
47Pancreatic fibrosis (HP:0100732)2.19227764
48Abnormality of macular pigmentation (HP:0008002)2.18615646
49Impaired smooth pursuit (HP:0007772)2.16644616
50Dynein arm defect of respiratory motile cilia (HP:0012255)2.15291492
51Absent/shortened dynein arms (HP:0200106)2.15291492
52Fetal akinesia sequence (HP:0001989)2.15111080
53True hermaphroditism (HP:0010459)2.12851768
54Degeneration of the lateral corticospinal tracts (HP:0002314)2.12641578
55Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)2.12641578
56Abnormal respiratory epithelium morphology (HP:0012253)2.12374311
57Abnormal respiratory motile cilium morphology (HP:0005938)2.12374311
58Split foot (HP:0001839)2.11876174
59Epileptiform EEG discharges (HP:0011182)2.09434848
60Abnormality of chromosome stability (HP:0003220)2.09272582
61Stomatitis (HP:0010280)2.08410941
62Curly hair (HP:0002212)2.08084548
63Cortical dysplasia (HP:0002539)2.07500982
64Nephroblastoma (Wilms tumor) (HP:0002667)2.03209653
65Depression (HP:0000716)2.02734469
66Stomach cancer (HP:0012126)2.02696898
67Abnormal eating behavior (HP:0100738)2.01177716
68Growth hormone deficiency (HP:0000824)2.00779131
69Exotropia (HP:0000577)2.00594245
70Genital tract atresia (HP:0001827)1.99222602
71Hyperglycinemia (HP:0002154)1.96231954
72Drooling (HP:0002307)1.95600418
73Excessive salivation (HP:0003781)1.95600418
74Colon cancer (HP:0003003)1.95414069
75Disinhibition (HP:0000734)1.95230082
76Dyskinesia (HP:0100660)1.95074993
77Renal hypoplasia (HP:0000089)1.94915865
78Oligodactyly (HP:0012165)1.94220146
79Poor coordination (HP:0002370)1.93381798
80Severe visual impairment (HP:0001141)1.92664763
81Keratoconjunctivitis (HP:0001096)1.91382194
82Ankle clonus (HP:0011448)1.91338424
83EEG with generalized epileptiform discharges (HP:0011198)1.91049021
84Hypoplasia of the pons (HP:0012110)1.90808434
85Abnormality of the corticospinal tract (HP:0002492)1.90361734
86Keratoconjunctivitis sicca (HP:0001097)1.90270892
87Myositis (HP:0100614)1.89496014
88Agitation (HP:0000713)1.89210433
89Amblyopia (HP:0000646)1.88829167
90Recurrent gram-negative bacterial infections (HP:0005420)1.88733172
91Neuroendocrine neoplasm (HP:0100634)1.88354374
92Hepatoblastoma (HP:0002884)1.88137009
93Birth length less than 3rd percentile (HP:0003561)1.87774901
94Hypothermia (HP:0002045)1.87352522
95Vaginal atresia (HP:0000148)1.87055613
96Urinary urgency (HP:0000012)1.86972993
97Abnormal lung lobation (HP:0002101)1.86317498
98Stereotypic behavior (HP:0000733)1.85848415
99Encephalitis (HP:0002383)1.85142069
100Impaired social interactions (HP:0000735)1.84838748
101Abnormal social behavior (HP:0012433)1.84838748
102Methylmalonic acidemia (HP:0002912)1.84675152
103Specific learning disability (HP:0001328)1.83669732
104Hip dysplasia (HP:0001385)1.83555802
105Papilledema (HP:0001085)1.82920660
106Spinal canal stenosis (HP:0003416)1.82405760
107Narrow forehead (HP:0000341)1.82374518
108Abnormal respiratory motile cilium physiology (HP:0012261)1.81085917
109Atrophy/Degeneration involving motor neurons (HP:0007373)1.80491764
110Generalized hypopigmentation of hair (HP:0011358)1.80066776
111Agnosia (HP:0010524)1.80046423
112Microvesicular hepatic steatosis (HP:0001414)1.79273865
113Poor suck (HP:0002033)1.78829854
114Abnormality of the pons (HP:0007361)1.78540883
115Cupped ear (HP:0000378)1.78477330
116Chromsome breakage (HP:0040012)1.78295341
117Hypsarrhythmia (HP:0002521)1.77937451
118Fair hair (HP:0002286)1.77820147
119Abnormality of ocular smooth pursuit (HP:0000617)1.76333410
120Chromosomal breakage induced by crosslinking agents (HP:0003221)1.75843383
121Postaxial hand polydactyly (HP:0001162)1.75827668
122Polyphagia (HP:0002591)1.75351690
123Pheochromocytoma (HP:0002666)1.74819267
124Broad foot (HP:0001769)1.74550556
125Spastic gait (HP:0002064)1.74133571
126Bradykinesia (HP:0002067)1.73701770
127Abnormality of salivation (HP:0100755)1.72489485
128Abolished electroretinogram (ERG) (HP:0000550)1.71735885
129Megalencephaly (HP:0001355)1.71487727
130Abnormality of the labia minora (HP:0012880)1.71468832
131Limb hypertonia (HP:0002509)1.70904657
132Renal cortical cysts (HP:0000803)1.70750613
133Limb dystonia (HP:0002451)1.70008635
134Aplasia/Hypoplasia of the uvula (HP:0010293)1.69855781
135Macroglossia (HP:0000158)1.69104457
136Abnormality of dental color (HP:0011073)1.67972985
137Blue irides (HP:0000635)1.67307177
138Aplasia/Hypoplasia of the sternum (HP:0006714)1.66663269
139Lissencephaly (HP:0001339)1.66488047
140Recurrent bacterial skin infections (HP:0005406)1.65593638
141Astigmatism (HP:0000483)1.65060229
142Rhinitis (HP:0012384)1.64841063
143Abnormality of the renal medulla (HP:0100957)1.64704884
144Pancreatic cysts (HP:0001737)1.64537555
145Rhabdomyosarcoma (HP:0002859)1.63909569
146Absent eyelashes (HP:0000561)1.63775260
147Decreased central vision (HP:0007663)1.63766152
148Urinary bladder sphincter dysfunction (HP:0002839)1.63534984
149Postural instability (HP:0002172)1.63417326
150Decreased testicular size (HP:0008734)1.63370315
151Diplopia (HP:0000651)1.61950255
152Abnormality of binocular vision (HP:0011514)1.61950255
153Decreased circulating renin level (HP:0003351)1.61811492
154Nephronophthisis (HP:0000090)1.60385084
155Median cleft lip (HP:0000161)1.60294080
156Widely spaced teeth (HP:0000687)1.58670417
157Sleep apnea (HP:0010535)1.56542037
158Scanning speech (HP:0002168)1.56328188
159Embryonal renal neoplasm (HP:0011794)1.54859341
160Dysdiadochokinesis (HP:0002075)1.53561308
161Annular pancreas (HP:0001734)1.53301677
162Esotropia (HP:0000565)1.52514899
163Gastroesophageal reflux (HP:0002020)1.52197216
164Optic nerve hypoplasia (HP:0000609)1.51763833
165Abnormality of midbrain morphology (HP:0002418)1.50791158
166Molar tooth sign on MRI (HP:0002419)1.50791158

Predicted kinase interactions (KEA)

RankGene SetZ-score
1EPHA44.36346328
2NTRK34.28419930
3SIK33.55970413
4CASK3.39277841
5MAP2K72.98987179
6MAP3K42.72640726
7MAP3K122.71419846
8TNIK2.57668074
9PRPF4B2.55240357
10FRK2.50728514
11MARK12.44835359
12TRIM282.43599806
13EIF2AK12.18590580
14MINK12.14084586
15NUAK12.02109818
16MAP3K91.99462402
17VRK11.90901286
18MAPK131.76667987
19KSR11.69792638
20DAPK11.62978952
21PLK21.62398345
22CDK191.56772169
23SGK21.55988869
24DYRK21.55767862
25NTRK21.55680118
26IRAK21.51169552
27SIK21.50709815
28DAPK21.50161670
29BMPR21.47691687
30RIPK41.47074399
31MAP2K41.40841125
32AKT31.34868063
33STK161.33880086
34DYRK31.30501712
35IRAK11.28946874
36IRAK41.25874848
37MAP4K21.24008201
38MUSK1.23648506
39EPHA31.14414667
40SRPK11.12442363
41BRD41.12162745
42SGK2231.11717172
43SGK4941.11717172
44MKNK21.11463203
45CDK51.10680987
46PLK31.09011545
47PRKCG1.02121016
48RPS6KA41.00187660
49BRSK20.99352862
50CCNB10.96883504
51BRAF0.96410670
52CAMKK10.92980493
53PAK30.92462369
54ERBB30.91405763
55ADRBK20.90398926
56CSNK1A1L0.90189300
57NME10.89677574
58MAP3K50.89154725
59CAMKK20.88768582
60MAP2K60.88355425
61PAK60.86494846
62PLK40.86185021
63CSNK1G10.85025562
64SGK30.84777856
65CSNK1G30.84331901
66FGR0.80894017
67GRK50.80294385
68MAP3K130.80026728
69TAOK20.79516288
70GRK70.79011589
71BCR0.76212450
72CDK180.75778590
73PRKD30.74829757
74BLK0.73934803
75CDC70.73755413
76DYRK1A0.73490216
77TNK20.71749546
78CAMK2A0.70727958
79FES0.70224884
80STK380.69743627
81NEK60.68128332
82STK38L0.66989425
83ARAF0.66765153
84TAOK30.66661042
85ACVR1B0.66633375
86TSSK60.65161250
87SGK10.64747433
88CAMK10.64715572
89BRSK10.64610933
90CAMK2B0.64274155
91CDK80.64153019
92CAMK1G0.64084557
93WEE10.63606686
94MKNK10.62672719
95MAP3K20.62244623
96MARK30.61845715
97CDK150.61361518
98UHMK10.60594190
99TAOK10.59219831
100PRKCE0.59194731
101YES10.58468020
102RAF10.58296579
103CDK140.58035147
104MAP3K60.57555045
105NTRK10.57257141
106JAK20.56493783
107DYRK1B0.55322232
108CSK0.54743110
109CDK11A0.54374589
110CDK30.52184837
111CAMK1D0.52083160
112HCK0.51910870
113PNCK0.50678161
114NLK0.49973149
115TAF10.49873647
116BUB10.49463068
117FGFR20.48604144
118LATS10.47681971
119OXSR10.47670741
120NEK10.47066440
121STK110.46582086
122GRK60.45290508
123SYK0.45218858
124EIF2AK20.44974481
125PKN10.44535469
126TXK0.43373478
127ERBB20.42106895
128WNK30.41509893
129LYN0.41307824
130FGFR30.40124237
131RPS6KB10.39530456
132EIF2AK30.39207374
133CSNK1G20.38710851
134BMPR1B0.37279755
135ADRBK10.36935883
136KSR20.36130891
137CAMK40.33410144
138PRKCB0.32958688
139PINK10.32649288
140RPS6KA30.30874188
141ATR0.29965802
142PRKCZ0.29184038
143MAPK100.29005619
144PRKCH0.28546471
145MARK20.28437974
146CSNK1A10.28267040

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050333.80797871
2Synthesis and degradation of ketone bodies_Homo sapiens_hsa000723.40068670
3Pantothenate and CoA biosynthesis_Homo sapiens_hsa007703.00168273
4Synaptic vesicle cycle_Homo sapiens_hsa047212.84648782
5Olfactory transduction_Homo sapiens_hsa047402.78314764
6Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.74943634
7Circadian entrainment_Homo sapiens_hsa047132.66273451
8Morphine addiction_Homo sapiens_hsa050322.64191335
9Long-term potentiation_Homo sapiens_hsa047202.62379128
10Propanoate metabolism_Homo sapiens_hsa006402.49502190
11Amphetamine addiction_Homo sapiens_hsa050312.43540302
12GABAergic synapse_Homo sapiens_hsa047272.43228335
13Glutamatergic synapse_Homo sapiens_hsa047242.39486162
14Dopaminergic synapse_Homo sapiens_hsa047282.28754040
15Protein export_Homo sapiens_hsa030602.27831160
16Taste transduction_Homo sapiens_hsa047421.90345375
17Serotonergic synapse_Homo sapiens_hsa047261.85343557
18Butanoate metabolism_Homo sapiens_hsa006501.84911019
19Insulin secretion_Homo sapiens_hsa049111.75978936
20Steroid biosynthesis_Homo sapiens_hsa001001.75596499
21Salivary secretion_Homo sapiens_hsa049701.70263963
22Cholinergic synapse_Homo sapiens_hsa047251.70232751
23Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.69398151
24Cocaine addiction_Homo sapiens_hsa050301.69259908
25Collecting duct acid secretion_Homo sapiens_hsa049661.67741831
26Long-term depression_Homo sapiens_hsa047301.65837054
27Renin secretion_Homo sapiens_hsa049241.64066299
28Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.62700226
29Calcium signaling pathway_Homo sapiens_hsa040201.59839217
30Aldosterone synthesis and secretion_Homo sapiens_hsa049251.56314548
31Phototransduction_Homo sapiens_hsa047441.53006974
32Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.47376522
33Gastric acid secretion_Homo sapiens_hsa049711.43139983
34Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.42363806
35Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.40098474
36Oxytocin signaling pathway_Homo sapiens_hsa049211.35243150
37Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.32511745
38SNARE interactions in vesicular transport_Homo sapiens_hsa041301.31932834
39Oocyte meiosis_Homo sapiens_hsa041141.25228558
40Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.23900719
41NOD-like receptor signaling pathway_Homo sapiens_hsa046211.20419192
42Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.20380686
43Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.18890887
44Vibrio cholerae infection_Homo sapiens_hsa051101.13090676
45Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.12854746
46Regulation of autophagy_Homo sapiens_hsa041401.10751524
47GnRH signaling pathway_Homo sapiens_hsa049121.10726661
48cAMP signaling pathway_Homo sapiens_hsa040241.10298663
49Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.07803104
50Gap junction_Homo sapiens_hsa045401.06489677
51Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.03914648
52Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050141.00114768
53Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.98985271
54Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.98346300
55Type I diabetes mellitus_Homo sapiens_hsa049400.97475825
56Alcoholism_Homo sapiens_hsa050340.96850340
57Legionellosis_Homo sapiens_hsa051340.96840147
58Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.96098237
59Chemokine signaling pathway_Homo sapiens_hsa040620.93974499
60Phosphatidylinositol signaling system_Homo sapiens_hsa040700.93659567
61Osteoclast differentiation_Homo sapiens_hsa043800.93204257
62Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.91447515
63ErbB signaling pathway_Homo sapiens_hsa040120.90988640
64cGMP-PKG signaling pathway_Homo sapiens_hsa040220.88242962
65Axon guidance_Homo sapiens_hsa043600.85683675
66Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.85334923
67Melanogenesis_Homo sapiens_hsa049160.83702206
68Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.82155680
69Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.81567425
70RNA degradation_Homo sapiens_hsa030180.79897638
71Carbohydrate digestion and absorption_Homo sapiens_hsa049730.79546303
72Fatty acid biosynthesis_Homo sapiens_hsa000610.77729376
73Glioma_Homo sapiens_hsa052140.77160580
74Estrogen signaling pathway_Homo sapiens_hsa049150.76669666
75Fatty acid elongation_Homo sapiens_hsa000620.76152066
76Dorso-ventral axis formation_Homo sapiens_hsa043200.74334652
77Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.74308497
78Homologous recombination_Homo sapiens_hsa034400.73935024
79Peroxisome_Homo sapiens_hsa041460.73926220
80Ether lipid metabolism_Homo sapiens_hsa005650.71911694
81FoxO signaling pathway_Homo sapiens_hsa040680.70749086
82DNA replication_Homo sapiens_hsa030300.67257906
83Purine metabolism_Homo sapiens_hsa002300.66842456
84Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.66759834
85Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.66623670
86RNA polymerase_Homo sapiens_hsa030200.66086254
87Wnt signaling pathway_Homo sapiens_hsa043100.65956219
88Basal transcription factors_Homo sapiens_hsa030220.65478268
89Type II diabetes mellitus_Homo sapiens_hsa049300.65103741
90Vascular smooth muscle contraction_Homo sapiens_hsa042700.64676256
91Cardiac muscle contraction_Homo sapiens_hsa042600.64498572
92Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.63818967
93Neurotrophin signaling pathway_Homo sapiens_hsa047220.63377349
94Nitrogen metabolism_Homo sapiens_hsa009100.62732424
95Thyroid hormone synthesis_Homo sapiens_hsa049180.62317797
96Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.62316874
97Fanconi anemia pathway_Homo sapiens_hsa034600.62157879
98Fatty acid metabolism_Homo sapiens_hsa012120.62008999
99Mismatch repair_Homo sapiens_hsa034300.60951366
100mRNA surveillance pathway_Homo sapiens_hsa030150.60426888
101RNA transport_Homo sapiens_hsa030130.60072753
102Tuberculosis_Homo sapiens_hsa051520.59977291
103MAPK signaling pathway_Homo sapiens_hsa040100.58764832
104Parkinsons disease_Homo sapiens_hsa050120.58599488
105Pyruvate metabolism_Homo sapiens_hsa006200.57696871
106Huntingtons disease_Homo sapiens_hsa050160.55157612
107Alzheimers disease_Homo sapiens_hsa050100.54505141
108Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.53525405
109Linoleic acid metabolism_Homo sapiens_hsa005910.53343022
110Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.51990145
111N-Glycan biosynthesis_Homo sapiens_hsa005100.50523607
112Primary bile acid biosynthesis_Homo sapiens_hsa001200.50465386
113Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.49970124
114Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.48896939
115Prolactin signaling pathway_Homo sapiens_hsa049170.48593146
116Base excision repair_Homo sapiens_hsa034100.47733606
117Colorectal cancer_Homo sapiens_hsa052100.47723349
118Cell cycle_Homo sapiens_hsa041100.47562987
119Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.47486817
120Renal cell carcinoma_Homo sapiens_hsa052110.47478176
121Oxidative phosphorylation_Homo sapiens_hsa001900.46865591
122Circadian rhythm_Homo sapiens_hsa047100.46516062
123Nucleotide excision repair_Homo sapiens_hsa034200.46451372
124Measles_Homo sapiens_hsa051620.46377720
125Ras signaling pathway_Homo sapiens_hsa040140.45170892
126Endometrial cancer_Homo sapiens_hsa052130.44795980
127Cysteine and methionine metabolism_Homo sapiens_hsa002700.44646334
128Pancreatic secretion_Homo sapiens_hsa049720.44451264
129Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.41990529
130T cell receptor signaling pathway_Homo sapiens_hsa046600.41962398
131Sphingolipid signaling pathway_Homo sapiens_hsa040710.41737931
132Choline metabolism in cancer_Homo sapiens_hsa052310.41672127
133Rap1 signaling pathway_Homo sapiens_hsa040150.41066565
134Caffeine metabolism_Homo sapiens_hsa002320.40504821
135Pyrimidine metabolism_Homo sapiens_hsa002400.40472946
136Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.40308854
137Non-homologous end-joining_Homo sapiens_hsa034500.39675910
138Jak-STAT signaling pathway_Homo sapiens_hsa046300.39383343
139Platelet activation_Homo sapiens_hsa046110.38575362
140Non-small cell lung cancer_Homo sapiens_hsa052230.37446502
141Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.37099606
142Spliceosome_Homo sapiens_hsa030400.36080792
143Inositol phosphate metabolism_Homo sapiens_hsa005620.34288916
144African trypanosomiasis_Homo sapiens_hsa051430.34173757
145Phospholipase D signaling pathway_Homo sapiens_hsa040720.34160142
146Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.33967488

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