UCHL5

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1DNA deamination (GO:0045006)5.41177210
2telomere maintenance via semi-conservative replication (GO:0032201)5.01141973
3nuclear pore organization (GO:0006999)4.87929784
4DNA strand elongation involved in DNA replication (GO:0006271)4.80147577
5DNA replication checkpoint (GO:0000076)4.74975220
6proteasome assembly (GO:0043248)4.59651484
7DNA strand elongation (GO:0022616)4.57509841
8DNA replication initiation (GO:0006270)4.56991969
9ribosome assembly (GO:0042255)4.55805044
10telomere maintenance via recombination (GO:0000722)4.50164127
11CENP-A containing nucleosome assembly (GO:0034080)4.22969734
12chromatin remodeling at centromere (GO:0031055)4.16165284
13mitotic recombination (GO:0006312)4.15620266
14ribosome biogenesis (GO:0042254)4.13865139
15regulation of nuclear cell cycle DNA replication (GO:0033262)4.11478505
16maturation of SSU-rRNA (GO:0030490)4.08435555
17telomere maintenance via telomere lengthening (GO:0010833)4.03978767
18nuclear pore complex assembly (GO:0051292)4.03724378
19mitotic metaphase plate congression (GO:0007080)3.99776470
20termination of RNA polymerase III transcription (GO:0006386)3.99382734
21transcription elongation from RNA polymerase III promoter (GO:0006385)3.99382734
22deoxyribonucleotide biosynthetic process (GO:0009263)3.98418765
23nucleobase biosynthetic process (GO:0046112)3.97176033
24ribonucleoprotein complex biogenesis (GO:0022613)3.95762538
25mitotic sister chromatid segregation (GO:0000070)3.93420845
26ribosomal large subunit biogenesis (GO:0042273)3.91595947
27ribosomal small subunit assembly (GO:0000028)3.90157796
28kinetochore organization (GO:0051383)3.89492408
29purine nucleobase biosynthetic process (GO:0009113)3.88268152
30sister chromatid segregation (GO:0000819)3.84626253
31kinetochore assembly (GO:0051382)3.81555766
32rRNA modification (GO:0000154)3.81265469
33formation of translation preinitiation complex (GO:0001731)3.78414402
34ribosomal small subunit biogenesis (GO:0042274)3.70087661
35negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.69277978
36spliceosomal snRNP assembly (GO:0000387)3.69066858
37deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.67993359
38double-strand break repair via nonhomologous end joining (GO:0006303)3.62079555
39non-recombinational repair (GO:0000726)3.62079555
40anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.59673502
41folic acid-containing compound biosynthetic process (GO:0009396)3.59415135
42regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.58079610
43DNA replication-independent nucleosome organization (GO:0034724)3.57743588
44DNA replication-independent nucleosome assembly (GO:0006336)3.57743588
45maturation of 5.8S rRNA (GO:0000460)3.56968635
46positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.56962402
47regulation of double-strand break repair via homologous recombination (GO:0010569)3.56544653
48pseudouridine synthesis (GO:0001522)3.56318905
49nucleotide-excision repair, DNA gap filling (GO:0006297)3.55105558
50transcription-coupled nucleotide-excision repair (GO:0006283)3.53905418
51rRNA processing (GO:0006364)3.51735369
527-methylguanosine mRNA capping (GO:0006370)3.50374479
53mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.47490109
54histone exchange (GO:0043486)3.46847196
557-methylguanosine RNA capping (GO:0009452)3.45082264
56RNA capping (GO:0036260)3.45082264
57metaphase plate congression (GO:0051310)3.43252052
58mitotic sister chromatid cohesion (GO:0007064)3.43136060
59DNA-dependent DNA replication (GO:0006261)3.41741336
60rRNA metabolic process (GO:0016072)3.41291932
61protein localization to chromosome, centromeric region (GO:0071459)3.41062607
62regulation of mitochondrial translation (GO:0070129)3.37710953
63transcription from mitochondrial promoter (GO:0006390)3.36798751
64nucleobase-containing small molecule interconversion (GO:0015949)3.35969206
65meiotic chromosome segregation (GO:0045132)3.33748825
66spliceosomal complex assembly (GO:0000245)3.33601904
67regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.33247616
68IMP biosynthetic process (GO:0006188)3.33009393
69mitotic nuclear envelope disassembly (GO:0007077)3.32468500
70attachment of spindle microtubules to kinetochore (GO:0008608)3.32110619
71negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.31729741
72negative regulation of ligase activity (GO:0051352)3.31729741
73tRNA aminoacylation for protein translation (GO:0006418)3.31515379
74mitochondrial DNA replication (GO:0006264)3.31371362
75amino acid activation (GO:0043038)3.30921400
76tRNA aminoacylation (GO:0043039)3.30921400
77oxidative phosphorylation (GO:0006119)3.29984848
78resolution of meiotic recombination intermediates (GO:0000712)3.29460754
79DNA catabolic process, exonucleolytic (GO:0000738)3.26752293
80signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)3.25438913
81signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)3.25438913
82signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)3.25438913
83deoxyribonucleoside triphosphate metabolic process (GO:0009200)3.24911446
84exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.22074424
85protein localization to kinetochore (GO:0034501)3.21442489
86establishment of chromosome localization (GO:0051303)3.20631510
87regulation of centriole replication (GO:0046599)3.19524023
88G1/S transition of mitotic cell cycle (GO:0000082)3.19164235
89cell cycle G1/S phase transition (GO:0044843)3.19164235
90regulation of DNA endoreduplication (GO:0032875)3.19140658
91signal transduction involved in DNA integrity checkpoint (GO:0072401)3.18799049
92signal transduction involved in DNA damage checkpoint (GO:0072422)3.18799049
93cellular component biogenesis (GO:0044085)3.18494795
94DNA damage response, detection of DNA damage (GO:0042769)3.18274346
95DNA unwinding involved in DNA replication (GO:0006268)3.18117545
96transcription from RNA polymerase I promoter (GO:0006360)3.17276616
97DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:003.17091447
98mitochondrial RNA metabolic process (GO:0000959)3.15792361
99signal transduction involved in cell cycle checkpoint (GO:0072395)3.15517013
100establishment of viral latency (GO:0019043)3.14063044
101positive regulation of ubiquitin-protein transferase activity (GO:0051443)3.14049134
102DNA ligation (GO:0006266)3.13768531
103intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)3.12966472
104signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)3.12966472
105DNA replication-dependent nucleosome assembly (GO:0006335)3.12429268
106DNA replication-dependent nucleosome organization (GO:0034723)3.12429268
107regulation of cellular amino acid metabolic process (GO:0006521)3.11867087
108termination of RNA polymerase I transcription (GO:0006363)3.11248576
109establishment of integrated proviral latency (GO:0075713)3.11082447
110cullin deneddylation (GO:0010388)3.10647922
111mitotic chromosome condensation (GO:0007076)3.10540776
112deoxyribonucleoside diphosphate metabolic process (GO:0009186)3.09257470
113negative regulation of DNA-dependent DNA replication (GO:2000104)3.08784862
114nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.08708061
115viral transcription (GO:0019083)3.08083100
116translational termination (GO:0006415)3.07760722
117tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.07733001
118RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.07733001
119regulation of translational fidelity (GO:0006450)3.07619812
120nuclear envelope disassembly (GO:0051081)3.05458798
121membrane disassembly (GO:0030397)3.05458798
122viral mRNA export from host cell nucleus (GO:0046784)3.05221384
123L-methionine biosynthetic process from methylthioadenosine (GO:0019509)3.04468366
124transcription elongation from RNA polymerase I promoter (GO:0006362)3.03722769
125chaperone-mediated protein transport (GO:0072321)3.03367496
126negative regulation of mitotic sister chromatid separation (GO:2000816)3.03125025
127negative regulation of mitotic sister chromatid segregation (GO:0033048)3.03125025
128negative regulation of mitotic metaphase/anaphase transition (GO:0045841)3.03125025
129negative regulation of sister chromatid segregation (GO:0033046)3.03125025
130IMP metabolic process (GO:0046040)3.02916445
131histone mRNA metabolic process (GO:0008334)3.00794103
132pore complex assembly (GO:0046931)2.99777930
133protein deneddylation (GO:0000338)2.99541451
134regulation of attachment of spindle microtubules to kinetochore (GO:0051988)2.97693146
135spindle checkpoint (GO:0031577)2.97669477
136tetrahydrofolate metabolic process (GO:0046653)2.95504155
137DNA double-strand break processing (GO:0000729)2.95301389
138regulation of centrosome cycle (GO:0046605)2.94909262
139regulation of mitotic spindle checkpoint (GO:1903504)2.94575701
140regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)2.94575701
141mitotic spindle checkpoint (GO:0071174)2.90370447
142RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503)2.90130267
143negative regulation of chromosome segregation (GO:0051985)2.89497149
144postreplication repair (GO:0006301)2.89234577
145DNA topological change (GO:0006265)2.87418244

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human7.65021376
2MYC_18555785_ChIP-Seq_MESCs_Mouse4.45837828
3KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human4.19902812
4GABP_17652178_ChIP-ChIP_JURKAT_Human3.71104303
5* E2F4_17652178_ChIP-ChIP_JURKAT_Human3.67651589
6EST1_17652178_ChIP-ChIP_JURKAT_Human3.63966085
7* EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.52599526
8JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.51560882
9* ETS1_20019798_ChIP-Seq_JURKAT_Human3.32073089
10FOXM1_23109430_ChIP-Seq_U2OS_Human3.20117527
11FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human3.07499358
12* MYC_18358816_ChIP-ChIP_MESCs_Mouse3.04079566
13CREB1_15753290_ChIP-ChIP_HEK293T_Human3.02662487
14* MYC_19030024_ChIP-ChIP_MESCs_Mouse3.00892925
15* MYC_19079543_ChIP-ChIP_MESCs_Mouse2.95560289
16NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.83607758
17HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.78551887
18ELF1_17652178_ChIP-ChIP_JURKAT_Human2.60620391
19* VDR_23849224_ChIP-Seq_CD4+_Human2.59297768
20NELFA_20434984_ChIP-Seq_ESCs_Mouse2.45477181
21CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.45247191
22HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.43927280
23MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.35320305
24XRN2_22483619_ChIP-Seq_HELA_Human2.34640517
25CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.29901595
26E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.28102816
27E2F1_18555785_ChIP-Seq_MESCs_Mouse2.20062956
28DCP1A_22483619_ChIP-Seq_HELA_Human2.11717343
29* FOXP3_21729870_ChIP-Seq_TREG_Human2.10885478
30MYBL2_22936984_ChIP-ChIP_MESCs_Mouse2.04245801
31PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse2.03075380
32MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.02830323
33ELK1_19687146_ChIP-ChIP_HELA_Human2.01383542
34* TTF2_22483619_ChIP-Seq_HELA_Human1.97230094
35* THAP11_20581084_ChIP-Seq_MESCs_Mouse1.96395461
36YY1_21170310_ChIP-Seq_MESCs_Mouse1.96097995
37GABP_19822575_ChIP-Seq_HepG2_Human1.95211730
38* MYCN_18555785_ChIP-Seq_MESCs_Mouse1.87511461
39SRF_21415370_ChIP-Seq_HL-1_Mouse1.86589429
40SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.86512757
41AR_21909140_ChIP-Seq_LNCAP_Human1.86417339
42FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.85351628
43NANOG_18555785_ChIP-Seq_MESCs_Mouse1.80092649
44SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.76203114
45E2F1_21310950_ChIP-Seq_MCF-7_Human1.75789358
46* YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.71255042
47POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.69026839
48ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.66379921
49HOXB4_20404135_ChIP-ChIP_EML_Mouse1.64607489
50* TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.48400061
51CIITA_25753668_ChIP-Seq_RAJI_Human1.46101620
52ZFX_18555785_ChIP-Seq_MESCs_Mouse1.44885733
53* KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.44579844
54* FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.43516237
55PADI4_21655091_ChIP-ChIP_MCF-7_Human1.42002852
56POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.40862339
57PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.40225341
58NOTCH1_21737748_ChIP-Seq_TLL_Human1.37726947
59PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.35891238
60* SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.34481481
61EWS_26573619_Chip-Seq_HEK293_Human1.29274906
62KDM5A_27292631_Chip-Seq_BREAST_Human1.27645845
63TP63_19390658_ChIP-ChIP_HaCaT_Human1.25845309
64SALL1_21062744_ChIP-ChIP_HESCs_Human1.24695461
65ERG_20887958_ChIP-Seq_HPC-7_Mouse1.20620001
66TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.19558634
67ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.17178168
68MYC_18940864_ChIP-ChIP_HL60_Human1.12788618
69CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.11952976
70RBPJ_22232070_ChIP-Seq_NCS_Mouse1.10859372
71ELK1_22589737_ChIP-Seq_MCF10A_Human1.09541337
72STAT3_1855785_ChIP-Seq_MESCs_Mouse1.08798803
73* E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.06188899
74CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.05403245
75HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.04466557
76FUS_26573619_Chip-Seq_HEK293_Human1.03013461
77HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.02909364
78BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.02239276
79CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.01796726
80KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.99460976
81POU5F1_18700969_ChIP-ChIP_MESCs_Mouse0.98102585
82POU3F2_20337985_ChIP-ChIP_501MEL_Human0.95056741
83SPI1_22096565_ChIP-ChIP_GC-B_Mouse0.93172725
84ASXL1_24218140_ChIP-Seq_BMDM_Mouse0.93043642
85VDR_22108803_ChIP-Seq_LS180_Human0.90871093
86* KLF4_18555785_ChIP-Seq_MESCs_Mouse0.90531841
87SMAD1_18555785_ChIP-Seq_MESCs_Mouse0.90224403
88* SPI1_23547873_ChIP-Seq_NB4_Human0.90219100
89TFEB_21752829_ChIP-Seq_HELA_Human0.88795817
90DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.88193785
91SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.87709954
92* GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.87476085
93SOX2_18555785_ChIP-Seq_MESCs_Mouse0.87210476
94CEBPB_24764292_ChIP-Seq_MC3T3_Mouse0.86297501
95IGF1R_20145208_ChIP-Seq_DFB_Human0.85811640
96ESRRB_18555785_ChIP-Seq_MESCs_Mouse0.85662215
97CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.84231762
98FLI1_27457419_Chip-Seq_LIVER_Mouse0.81071998
99CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.80554081
100NANOG_18358816_ChIP-ChIP_MESCs_Mouse0.80026629
101HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.80004361
102EGR1_19374776_ChIP-ChIP_THP-1_Human0.78970036
103FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.78658584
104RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.77863597
105* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.77517027
106* TRIM28_19339689_ChIP-ChIP_MESCs_Mouse0.74301286
107* CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.73746781
108SOX17_20123909_ChIP-Seq_XEN_Mouse0.71308955
109KLF5_18264089_ChIP-ChIP_MESCs_Mouse0.70418627
110KLF4_18264089_ChIP-ChIP_MESCs_Mouse0.70418627
111KLF2_18264089_ChIP-ChIP_MESCs_Mouse0.70418627
112ELF5_23300383_ChIP-Seq_T47D_Human0.70342532
113SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.69385423
114* RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse0.67889151
115CHD1_26751641_Chip-Seq_LNCaP_Human0.66356671
116TBX5_21415370_ChIP-Seq_HL-1_Mouse0.66150616
117* CTCF_18555785_ChIP-Seq_MESCs_Mouse0.65157120
118KLF4_18358816_ChIP-ChIP_MESCs_Mouse0.65083321
119NANOG_16153702_ChIP-ChIP_HESCs_Human0.62699236
120* RBPJ_21746931_ChIP-Seq_IB4_Human0.57861121
121ZNF263_19887448_ChIP-Seq_K562_Human0.57190495
122TP53_22573176_ChIP-Seq_HFKS_Human0.57112645

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching6.01254881
2MP0010094_abnormal_chromosome_stability4.87341824
3MP0003111_abnormal_nucleus_morphology4.77297274
4MP0008058_abnormal_DNA_repair4.38624642
5MP0004957_abnormal_blastocyst_morpholog4.34764266
6MP0008057_abnormal_DNA_replication4.25690564
7MP0003077_abnormal_cell_cycle4.04909448
8MP0008877_abnormal_DNA_methylation3.32725639
9MP0008007_abnormal_cellular_replicative3.18981866
10MP0008932_abnormal_embryonic_tissue3.01418748
11MP0003786_premature_aging2.85764921
12MP0003718_maternal_effect2.48209472
13MP0001529_abnormal_vocalization2.15751973
14MP0002396_abnormal_hematopoietic_system2.08196865
15MP0002160_abnormal_reproductive_system1.99253731
16MP0003123_paternal_imprinting1.96233010
17MP0006292_abnormal_olfactory_placode1.84797486
18MP0000350_abnormal_cell_proliferation1.83754549
19MP0001730_embryonic_growth_arrest1.75319753
20MP0003186_abnormal_redox_activity1.74164435
21MP0003941_abnormal_skin_development1.71468519
22MP0000490_abnormal_crypts_of1.67187756
23MP0002210_abnormal_sex_determination1.66207742
24MP0001853_heart_inflammation1.63142041
25MP0009379_abnormal_foot_pigmentation1.58968200
26MP0001188_hyperpigmentation1.56494036
27MP0005389_reproductive_system_phenotype1.54925419
28MP0002837_dystrophic_cardiac_calcinosis1.54224298
29MP0000313_abnormal_cell_death1.53828075
30MP0003221_abnormal_cardiomyocyte_apopto1.53049308
31MP0005623_abnormal_meninges_morphology1.50170564
32MP0002102_abnormal_ear_morphology1.43208483
33MP0001145_abnormal_male_reproductive1.43134178
34MP0003806_abnormal_nucleotide_metabolis1.41025294
35MP0002877_abnormal_melanocyte_morpholog1.37535373
36MP0002163_abnormal_gland_morphology1.35927206
37MP0002019_abnormal_tumor_incidence1.34387896
38MP0003315_abnormal_perineum_morphology1.34382763
39MP0006035_abnormal_mitochondrial_morpho1.33226523
40MP0001697_abnormal_embryo_size1.29314111
41MP0004215_abnormal_myocardial_fiber1.29013038
42MP0002132_abnormal_respiratory_system1.28326952
43MP0005075_abnormal_melanosome_morpholog1.28187881
44MP0001929_abnormal_gametogenesis1.26647768
45MP0000566_synostosis1.26304224
46MP0000653_abnormal_sex_gland1.25985371
47MP0004084_abnormal_cardiac_muscle1.24183924
48MP0004145_abnormal_muscle_electrophysio1.23514925
49MP0006072_abnormal_retinal_apoptosis1.22975544
50MP0006036_abnormal_mitochondrial_physio1.21692279
51MP0004808_abnormal_hematopoietic_stem1.18512467
52MP0009333_abnormal_splenocyte_physiolog1.17676124
53MP0002277_abnormal_respiratory_mucosa1.16848933
54* MP0002080_prenatal_lethality1.16633078
55MP0001986_abnormal_taste_sensitivity1.14388079
56* MP0005380_embryogenesis_phenotype1.13376615
57* MP0001672_abnormal_embryogenesis/_devel1.13376615
58MP0010307_abnormal_tumor_latency1.13073902
59MP0001661_extended_life_span1.12061183
60MP0001919_abnormal_reproductive_system1.10147871
61MP0002009_preneoplasia1.09795506
62MP0010352_gastrointestinal_tract_polyps1.08932028
63MP0000358_abnormal_cell_content/1.08906003
64MP0001119_abnormal_female_reproductive1.07096620
65MP0003763_abnormal_thymus_physiology1.06816220
66MP0002085_abnormal_embryonic_tissue1.02549020
67MP0000703_abnormal_thymus_morphology1.02294418
68MP0008995_early_reproductive_senescence1.01771991
69MP0000015_abnormal_ear_pigmentation0.98751233
70MP0004133_heterotaxia0.97306138
71MP0002722_abnormal_immune_system0.96331742
72MP0002938_white_spotting0.96124320
73MP0000689_abnormal_spleen_morphology0.95367797
74MP0005408_hypopigmentation0.95313133
75MP0003567_abnormal_fetal_cardiomyocyte0.93006777
76MP0002269_muscular_atrophy0.92770009
77MP0000749_muscle_degeneration0.92298808
78* MP0003984_embryonic_growth_retardation0.90092287
79MP0002398_abnormal_bone_marrow0.89998844
80MP0002095_abnormal_skin_pigmentation0.89421457
81MP0001764_abnormal_homeostasis0.88608450
82MP0005379_endocrine/exocrine_gland_phen0.87797944
83MP0000858_altered_metastatic_potential0.85863727
84MP0005187_abnormal_penis_morphology0.85843656
85* MP0002088_abnormal_embryonic_growth/wei0.85529695
86MP0005384_cellular_phenotype0.84727886
87MP0005171_absent_coat_pigmentation0.84335064
88MP0003890_abnormal_embryonic-extraembry0.84092743
89MP0009697_abnormal_copulation0.83688335
90MP0001545_abnormal_hematopoietic_system0.81585185
91MP0005397_hematopoietic_system_phenotyp0.81585185
92MP0002234_abnormal_pharynx_morphology0.80568987
93MP0004233_abnormal_muscle_weight0.79995367
94MP0003121_genomic_imprinting0.79721986
95MP0005266_abnormal_metabolism0.79293510
96MP0009046_muscle_twitch0.76806453
97MP0005174_abnormal_tail_pigmentation0.76617648
98MP0001293_anophthalmia0.76377573
99MP0003646_muscle_fatigue0.76197690
100MP0003698_abnormal_male_reproductive0.75839056
101MP0001186_pigmentation_phenotype0.73125046
102MP0002086_abnormal_extraembryonic_tissu0.72826487
103MP0002429_abnormal_blood_cell0.72801168
104MP0005330_cardiomyopathy0.70962361
105MP0005621_abnormal_cell_physiology0.70445512
106MP0008260_abnormal_autophagy0.69205568
107MP0005499_abnormal_olfactory_system0.69131731
108MP0005394_taste/olfaction_phenotype0.69131731
109MP0002177_abnormal_outer_ear0.68809463
110MP0003656_abnormal_erythrocyte_physiolo0.68541108
111MP0005253_abnormal_eye_physiology0.68415356
112MP0004197_abnormal_fetal_growth/weight/0.67867777
113MP0002084_abnormal_developmental_patter0.67517759
114MP0004147_increased_porphyrin_level0.66718795
115MP0005395_other_phenotype0.65410395
116MP0010030_abnormal_orbit_morphology0.64563134
117MP0005501_abnormal_skin_physiology0.64346604
118MP0000372_irregular_coat_pigmentation0.64249652
119MP0002075_abnormal_coat/hair_pigmentati0.64027781
120MP0005332_abnormal_amino_acid0.63891278
121MP0003137_abnormal_impulse_conducting0.63815199
122MP0000647_abnormal_sebaceous_gland0.63353644
123MP0000716_abnormal_immune_system0.61855426
124MP0001346_abnormal_lacrimal_gland0.61307916
125MP0005377_hearing/vestibular/ear_phenot0.61243913
126MP0003878_abnormal_ear_physiology0.61243913
127MP0003937_abnormal_limbs/digits/tail_de0.60974138
128MP0008770_decreased_survivor_rate0.60576076
129MP0008789_abnormal_olfactory_epithelium0.60064941
130MP0002751_abnormal_autonomic_nervous0.59819577
131MP0005636_abnormal_mineral_homeostasis0.59112207
132MP0001542_abnormal_bone_strength0.58306509
133MP0001835_abnormal_antigen_presentation0.57686752
134MP0002111_abnormal_tail_morphology0.53854614
135MP0001286_abnormal_eye_development0.52626834
136MP0000678_abnormal_parathyroid_gland0.52102396
137MP0003936_abnormal_reproductive_system0.51710588
138MP0002161_abnormal_fertility/fecundity0.51217040

Predicted human phenotypes

RankGene SetZ-score
1Birth length less than 3rd percentile (HP:0003561)5.57221620
2Breast hypoplasia (HP:0003187)4.84886274
3Chromsome breakage (HP:0040012)4.24573039
4Chromosomal breakage induced by crosslinking agents (HP:0003221)4.15759850
5Progressive external ophthalmoplegia (HP:0000590)3.93889402
6Muscle abnormality related to mitochondrial dysfunction (HP:0003800)3.93844859
7Reticulocytopenia (HP:0001896)3.84697780
8Abnormal number of erythroid precursors (HP:0012131)3.67606066
9Abnormality of cells of the erythroid lineage (HP:0012130)3.61553396
10Oral leukoplakia (HP:0002745)3.52525251
11Carpal bone hypoplasia (HP:0001498)3.42144137
12Abnormality of glycolysis (HP:0004366)3.41425417
13Aplastic anemia (HP:0001915)3.31150710
14Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)3.30886779
15Abnormality of the preputium (HP:0100587)3.27389738
16Meckel diverticulum (HP:0002245)3.24067862
17Increased serum pyruvate (HP:0003542)3.22156591
18Rough bone trabeculation (HP:0100670)3.20920865
19Abnormality of chromosome stability (HP:0003220)3.20329133
20Patellar aplasia (HP:0006443)3.17416006
21Volvulus (HP:0002580)3.13785969
22Hypoplasia of the pons (HP:0012110)3.08083995
23Cerebral hypomyelination (HP:0006808)3.07650414
24Methylmalonic acidemia (HP:0002912)3.05842672
25Abnormality of the ileum (HP:0001549)3.04575452
26Aplasia/Hypoplasia of the patella (HP:0006498)3.01812849
27Abnormality of the pons (HP:0007361)3.01155051
28Abnormality of the anterior horn cell (HP:0006802)2.98349006
29Degeneration of anterior horn cells (HP:0002398)2.98349006
30Cerebral edema (HP:0002181)2.86866080
31Increased serum lactate (HP:0002151)2.81357609
32Macrocytic anemia (HP:0001972)2.80583244
33Abnormality of alanine metabolism (HP:0010916)2.78304959
34Hyperalaninemia (HP:0003348)2.78304959
35Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.78304959
36Absent thumb (HP:0009777)2.76918899
37Progressive muscle weakness (HP:0003323)2.76812377
38Premature graying of hair (HP:0002216)2.73960260
39Type 2 muscle fiber atrophy (HP:0003554)2.73244920
40Aplasia/Hypoplasia of the uvula (HP:0010293)2.73049732
41Lipid accumulation in hepatocytes (HP:0006561)2.71264827
42Abnormal spermatogenesis (HP:0008669)2.70104890
43Microretrognathia (HP:0000308)2.69380701
44Abnormality of methionine metabolism (HP:0010901)2.63763099
45Type I transferrin isoform profile (HP:0003642)2.63331906
46Bone marrow hypocellularity (HP:0005528)2.60728263
47Acute necrotizing encephalopathy (HP:0006965)2.58828314
48Microvesicular hepatic steatosis (HP:0001414)2.56631518
49Duplicated collecting system (HP:0000081)2.56600112
50Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.56327460
51Decreased activity of mitochondrial respiratory chain (HP:0008972)2.56327460
52Absent radius (HP:0003974)2.53773031
53Granulocytopenia (HP:0001913)2.52202003
54Mitochondrial inheritance (HP:0001427)2.51977741
55Muscle fiber atrophy (HP:0100295)2.49983797
56Cerebellar dysplasia (HP:0007033)2.49775964
57Increased CSF lactate (HP:0002490)2.47645891
58Colon cancer (HP:0003003)2.46246006
59Pallor (HP:0000980)2.45731319
60Hyperglycinemia (HP:0002154)2.43811400
61Aplasia/Hypoplasia involving the carpal bones (HP:0006502)2.43663484
62Cholecystitis (HP:0001082)2.41938427
63Abnormal gallbladder physiology (HP:0012438)2.41938427
64Small intestinal stenosis (HP:0012848)2.41531195
65Duodenal stenosis (HP:0100867)2.41531195
66Hepatocellular necrosis (HP:0001404)2.39156637
67Absent forearm bone (HP:0003953)2.38378841
68Aplasia involving forearm bones (HP:0009822)2.38378841
69Impulsivity (HP:0100710)2.37136550
70Myelodysplasia (HP:0002863)2.36726517
71Abnormality of the renal collecting system (HP:0004742)2.36174878
72Abnormal trabecular bone morphology (HP:0100671)2.35986028
73Exercise intolerance (HP:0003546)2.34372423
74Methylmalonic aciduria (HP:0012120)2.32979245
75Horseshoe kidney (HP:0000085)2.32859807
76Selective tooth agenesis (HP:0001592)2.30785880
77Abnormality of serum amino acid levels (HP:0003112)2.29853314
78Abnormal mitochondria in muscle tissue (HP:0008316)2.29154610
79Aplasia/Hypoplasia of the sacrum (HP:0008517)2.29066471
80Proximal tubulopathy (HP:0000114)2.27874857
81Exertional dyspnea (HP:0002875)2.24768663
823-Methylglutaconic aciduria (HP:0003535)2.23157518
83Neoplasm of the pancreas (HP:0002894)2.22632975
84Pancytopenia (HP:0001876)2.22403731
85Multiple enchondromatosis (HP:0005701)2.21379824
86Increased hepatocellular lipid droplets (HP:0006565)2.19191187
87Triphalangeal thumb (HP:0001199)2.18621621
88Aplasia/Hypoplasia of the earlobes (HP:0009906)2.18239549
89Pancreatic islet-cell hyperplasia (HP:0004510)2.17180986
90Cleft eyelid (HP:0000625)2.16764619
91Abnormal lung lobation (HP:0002101)2.15707366
92Trismus (HP:0000211)2.15029212
93External ophthalmoplegia (HP:0000544)2.14958882
94Agnosia (HP:0010524)2.13811735
95Sparse eyelashes (HP:0000653)2.13290645
96Abnormality of DNA repair (HP:0003254)2.12975353
97Cellular immunodeficiency (HP:0005374)2.12874649
98Clubbing of toes (HP:0100760)2.12313955
99Hypoglycemic coma (HP:0001325)2.11675841
100Hepatic necrosis (HP:0002605)2.11437956
101Abnormal protein N-linked glycosylation (HP:0012347)2.09895774
102Abnormal protein glycosylation (HP:0012346)2.09895774
103Abnormal glycosylation (HP:0012345)2.09895774
104Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.09895774
10511 pairs of ribs (HP:0000878)2.09558699
106Reduced antithrombin III activity (HP:0001976)2.08516737
107Abnormality of the vitamin B12 metabolism (HP:0004341)2.08512079
108Homocystinuria (HP:0002156)2.07862571
109Abnormality of homocysteine metabolism (HP:0010919)2.07862571
110Secondary amenorrhea (HP:0000869)2.04873354
111Sloping forehead (HP:0000340)2.04021435
112Atrophy/Degeneration involving motor neurons (HP:0007373)2.03382085
113IgM deficiency (HP:0002850)2.02878300
114Megaloblastic anemia (HP:0001889)2.02690569
115Premature ovarian failure (HP:0008209)2.02483568
116Leukodystrophy (HP:0002415)2.02197236
117Tracheoesophageal fistula (HP:0002575)2.01536041
118Increased intramyocellular lipid droplets (HP:0012240)2.00323726
119Fatigue (HP:0012378)2.00052518
120Pancreatic cysts (HP:0001737)2.00040037
121Abnormality of the labia minora (HP:0012880)1.99622754
122Supernumerary spleens (HP:0009799)1.98569380
123Lactic acidosis (HP:0003128)1.97468170
124Azoospermia (HP:0000027)1.97271101
125Progressive macrocephaly (HP:0004481)1.95675155
126Abnormality of vitamin B metabolism (HP:0004340)1.95078307
127Nephroblastoma (Wilms tumor) (HP:0002667)1.95069458
128CNS hypomyelination (HP:0003429)1.93459340
129Unsteady gait (HP:0002317)1.91219879
130Septate vagina (HP:0001153)1.90443050
131Ectopic kidney (HP:0000086)1.89690093
132Type II lissencephaly (HP:0007260)1.89279071
133Abnormality of the duodenum (HP:0002246)1.88985455
134Aplasia/hypoplasia of the uterus (HP:0008684)1.88362604
135Acute encephalopathy (HP:0006846)1.87924202
136Abnormality of aspartate family amino acid metabolism (HP:0010899)1.87876060
137Medulloblastoma (HP:0002885)1.86828246
138Lymphoma (HP:0002665)1.86274980
139CNS demyelination (HP:0007305)1.86098312
140Embryonal renal neoplasm (HP:0011794)1.85700051
141Severe combined immunodeficiency (HP:0004430)1.85523961
142Renal cortical cysts (HP:0000803)1.84612652
143Postnatal microcephaly (HP:0005484)1.84233269
144Prominent metopic ridge (HP:0005487)1.83853222
145Combined immunodeficiency (HP:0005387)1.82426075
146Lethargy (HP:0001254)1.81899568
147Exercise-induced muscle cramps (HP:0003710)1.80672180
148Respiratory failure (HP:0002878)1.77972495
149Increased nuchal translucency (HP:0010880)1.75515237
150Retinal dysplasia (HP:0007973)1.75136217
151Renal Fanconi syndrome (HP:0001994)1.73563912
152Palpitations (HP:0001962)1.70944839
153Abnormality of the carotid arteries (HP:0005344)1.70938880
154Gout (HP:0001997)1.69340833

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BUB14.78642453
2IRAK34.41312079
3PLK44.35671741
4WEE13.75366132
5EIF2AK13.65478281
6STK163.52851610
7ZAK3.22800606
8CDC72.76133633
9SRPK12.59129573
10EIF2AK32.58163615
11IRAK42.50111660
12TRIM282.33439091
13TTK2.30488012
14VRK22.24453262
15TSSK62.07020619
16VRK11.95729373
17PDK21.83529615
18NEK11.81171212
19PLK11.78671398
20BRSK21.76666589
21MARK11.70207602
22NUAK11.65718443
23TESK21.64519600
24ACVR1B1.64008384
25PLK31.63540769
26IRAK21.63447600
27NEK21.51483204
28IRAK11.51038992
29TLK11.46714419
30NME21.44034927
31ATR1.43556907
32CCNB11.42588105
33BCR1.42257995
34MKNK11.39523561
35DYRK31.35271324
36EPHA21.33300394
37NME11.25596639
38MKNK21.24689545
39AURKB1.20958891
40EIF2AK21.13734030
41CHEK21.11676110
42BRSK11.06689182
43AURKA1.02757771
44CDK71.01507626
45MUSK0.99169095
46PIM20.96432177
47MARK30.95417726
48MAP4K20.94365470
49KDR0.94142488
50TAF10.93223836
51RPS6KB20.92715444
52PINK10.87002229
53ALK0.82751388
54RPS6KA40.81955820
55PRKCI0.80597968
56PBK0.80190575
57STK38L0.79668847
58TESK10.79488241
59CSNK1G30.78702552
60PAK40.78668499
61CHEK10.76045508
62STK40.74110672
63CSNK1A1L0.73983142
64PASK0.72685004
65AKT30.70323425
66OBSCN0.69054395
67PNCK0.68150851
68BRAF0.67385350
69MAP3K80.66804380
70CDK80.65764930
71MAPKAPK30.65262511
72WNK30.65046520
73CSNK1G10.64863778
74STK30.64651583
75CSNK2A10.63574769
76TEC0.63304321
77MAP3K120.62710260
78MAP3K110.61903896
79ATM0.61579018
80BMPR20.61199597
81LATS10.58452427
82CSNK1G20.57292080
83CSNK2A20.54871720
84CDK30.51000738
85STK390.49280334
86CDK20.47986437
87MAPKAPK50.47587107
88SCYL20.46017828
89ABL20.45347567
90RAF10.45306143
91BCKDK0.43956096
92DYRK20.43909700
93MAP3K40.43189431
94MST40.41661473
95PIM10.41479808
96MINK10.40975442
97PAK10.40386940
98CDK10.39331786
99RPS6KA50.39160439
100MST1R0.36760584
101LIMK10.35295367
102PHKG20.34741045
103PHKG10.34741045
104CDK40.34641240
105CDK90.34509588
106DAPK10.34367799
107NEK60.33440105
108PLK20.32361253
109BRD40.32136734
110TGFBR10.32114499
111OXSR10.31521835
112AKT20.30713588
113STK100.28844945
114ERBB40.28820877
115WNK40.27088309
116CDK180.25538830
117LATS20.24993485
118TXK0.24784764
119CSNK1D0.23593756
120CLK10.22948357
121SIK30.22874388
122MAPK140.22855595
123FRK0.22622378
124IKBKB0.22542182
125BLK0.21275156
126FLT30.21028349
127TAOK20.20274195
128BTK0.19268033
129CSNK1E0.19081382
130BMPR1B0.18286274
131YES10.17203374
132PRKDC0.16545176
133ADRBK20.14495065
134STK240.14463364
135LYN0.14247384
136NEK90.14072648
137ERBB30.13917166
138NLK0.13782391

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030305.00487526
2Proteasome_Homo sapiens_hsa030504.13740980
3Mismatch repair_Homo sapiens_hsa034304.07188567
4RNA polymerase_Homo sapiens_hsa030204.03506126
5Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.69559136
6Ribosome_Homo sapiens_hsa030103.68173752
7Homologous recombination_Homo sapiens_hsa034403.21932623
8Spliceosome_Homo sapiens_hsa030403.09737418
9Pyrimidine metabolism_Homo sapiens_hsa002402.98623655
10Base excision repair_Homo sapiens_hsa034102.77353192
11Nucleotide excision repair_Homo sapiens_hsa034202.74468227
12RNA transport_Homo sapiens_hsa030132.70043380
13Fanconi anemia pathway_Homo sapiens_hsa034602.67771444
14Cell cycle_Homo sapiens_hsa041102.30675473
15Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.27278842
16One carbon pool by folate_Homo sapiens_hsa006702.26263995
17Basal transcription factors_Homo sapiens_hsa030222.06332551
18Non-homologous end-joining_Homo sapiens_hsa034501.95584420
19RNA degradation_Homo sapiens_hsa030181.86964717
20Purine metabolism_Homo sapiens_hsa002301.74147057
21Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.71367761
22Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.61500743
23p53 signaling pathway_Homo sapiens_hsa041151.57342865
24Oxidative phosphorylation_Homo sapiens_hsa001901.54825561
25Parkinsons disease_Homo sapiens_hsa050121.54331002
26Pyruvate metabolism_Homo sapiens_hsa006201.48044773
27Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.46640138
28Huntingtons disease_Homo sapiens_hsa050161.44697893
29Propanoate metabolism_Homo sapiens_hsa006401.44483201
30Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.41117042
31Protein export_Homo sapiens_hsa030601.39082503
32mRNA surveillance pathway_Homo sapiens_hsa030151.24942273
33Epstein-Barr virus infection_Homo sapiens_hsa051691.24703057
34Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.12966057
35Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.10802472
36Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.00372198
37Folate biosynthesis_Homo sapiens_hsa007900.99244547
38Sulfur metabolism_Homo sapiens_hsa009200.94528762
39Cysteine and methionine metabolism_Homo sapiens_hsa002700.90562599
40Glutathione metabolism_Homo sapiens_hsa004800.85675529
41Fatty acid elongation_Homo sapiens_hsa000620.82716950
42Pentose phosphate pathway_Homo sapiens_hsa000300.79835234
43Systemic lupus erythematosus_Homo sapiens_hsa053220.79814281
44Oocyte meiosis_Homo sapiens_hsa041140.77869838
45Drug metabolism - other enzymes_Homo sapiens_hsa009830.77656220
46Alzheimers disease_Homo sapiens_hsa050100.75926962
47Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.75844505
48Butanoate metabolism_Homo sapiens_hsa006500.74974327
49Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.72641279
50Vitamin B6 metabolism_Homo sapiens_hsa007500.72352309
51Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.70373660
52Herpes simplex infection_Homo sapiens_hsa051680.70122118
53Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.68873223
54Cyanoamino acid metabolism_Homo sapiens_hsa004600.67692078
55Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.67629801
56Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.62975798
57Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.59916598
58Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.58168558
59Viral carcinogenesis_Homo sapiens_hsa052030.56148149
60Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.53791218
61Antigen processing and presentation_Homo sapiens_hsa046120.51092186
62Fatty acid metabolism_Homo sapiens_hsa012120.50389459
63SNARE interactions in vesicular transport_Homo sapiens_hsa041300.50123297
64Steroid biosynthesis_Homo sapiens_hsa001000.49783165
65Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.48474902
66Biosynthesis of amino acids_Homo sapiens_hsa012300.47306656
67Arachidonic acid metabolism_Homo sapiens_hsa005900.47231291
68Metabolic pathways_Homo sapiens_hsa011000.46885283
69Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.45319781
70Peroxisome_Homo sapiens_hsa041460.44998737
71HTLV-I infection_Homo sapiens_hsa051660.41171989
72Selenocompound metabolism_Homo sapiens_hsa004500.40318829
73Sulfur relay system_Homo sapiens_hsa041220.39239895
74Legionellosis_Homo sapiens_hsa051340.36585830
75Primary immunodeficiency_Homo sapiens_hsa053400.34179715
76Regulation of autophagy_Homo sapiens_hsa041400.34093619
77Fructose and mannose metabolism_Homo sapiens_hsa000510.34010826
78N-Glycan biosynthesis_Homo sapiens_hsa005100.32896650
79Nitrogen metabolism_Homo sapiens_hsa009100.32746973
80Other glycan degradation_Homo sapiens_hsa005110.32014906
81Galactose metabolism_Homo sapiens_hsa000520.30168204
82Thyroid cancer_Homo sapiens_hsa052160.27734325
83Measles_Homo sapiens_hsa051620.27051718
84Carbon metabolism_Homo sapiens_hsa012000.26595494
85NF-kappa B signaling pathway_Homo sapiens_hsa040640.26203147
86Pentose and glucuronate interconversions_Homo sapiens_hsa000400.25301813
87Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.25261931
88Renin-angiotensin system_Homo sapiens_hsa046140.24294570
89Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.23613373
90RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.23437029
91Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.22901941
92Shigellosis_Homo sapiens_hsa051310.20636072
93Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.19649732
94Apoptosis_Homo sapiens_hsa042100.19648295
95Olfactory transduction_Homo sapiens_hsa047400.18912452
96Alcoholism_Homo sapiens_hsa050340.17707063
97NOD-like receptor signaling pathway_Homo sapiens_hsa046210.16798116
98Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.15895620
99Influenza A_Homo sapiens_hsa051640.14290056
100Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.13972677
101Nicotine addiction_Homo sapiens_hsa050330.13624134
102Asthma_Homo sapiens_hsa053100.13585500
103Hematopoietic cell lineage_Homo sapiens_hsa046400.12908015
104Fatty acid degradation_Homo sapiens_hsa000710.11191921
105Intestinal immune network for IgA production_Homo sapiens_hsa046720.10737541
106Allograft rejection_Homo sapiens_hsa053300.10304912
107Arginine biosynthesis_Homo sapiens_hsa002200.09990499
108Glucagon signaling pathway_Homo sapiens_hsa049220.09005970
109Phototransduction_Homo sapiens_hsa047440.08849902
110Cardiac muscle contraction_Homo sapiens_hsa042600.08389772
111Sphingolipid metabolism_Homo sapiens_hsa006000.07446353
112Transcriptional misregulation in cancer_Homo sapiens_hsa052020.07008620
113Linoleic acid metabolism_Homo sapiens_hsa005910.06680414
114Arginine and proline metabolism_Homo sapiens_hsa003300.06396112
115beta-Alanine metabolism_Homo sapiens_hsa004100.02630302
116Tyrosine metabolism_Homo sapiens_hsa003500.02392380
117Autoimmune thyroid disease_Homo sapiens_hsa053200.02316142
118Lysine degradation_Homo sapiens_hsa003100.02045433
119HIF-1 signaling pathway_Homo sapiens_hsa040660.02021102
120Maturity onset diabetes of the young_Homo sapiens_hsa049500.01818734
121Hepatitis B_Homo sapiens_hsa051610.01565901
122Graft-versus-host disease_Homo sapiens_hsa053320.00989382
123Vitamin digestion and absorption_Homo sapiens_hsa049770.00849470
124TGF-beta signaling pathway_Homo sapiens_hsa043500.00755120
125Small cell lung cancer_Homo sapiens_hsa052220.00368443
126Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964-0.0350191
127Collecting duct acid secretion_Homo sapiens_hsa04966-0.0292920
128Other types of O-glycan biosynthesis_Homo sapiens_hsa00514-0.0184462
129Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980-0.0065313
130Taste transduction_Homo sapiens_hsa04742-0.0044061
131Circadian rhythm_Homo sapiens_hsa04710-0.0042104
1322-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210-0.0019786

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