Rank | Gene Set | Z-score |
---|---|---|
1 | signal peptide processing (GO:0006465) | 5.90045111 |
2 | ER overload response (GO:0006983) | 5.60168691 |
3 | Golgi transport vesicle coating (GO:0048200) | 5.52130518 |
4 | COPI coating of Golgi vesicle (GO:0048205) | 5.52130518 |
5 | regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway (GO:1902235 | 4.93966789 |
6 | erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222) | 4.88733904 |
7 | L-phenylalanine catabolic process (GO:0006559) | 4.88733904 |
8 | COPII vesicle coating (GO:0048208) | 4.63143793 |
9 | fatty acid elongation (GO:0030497) | 4.52780542 |
10 | nucleotide transmembrane transport (GO:1901679) | 4.39049391 |
11 | cellular ketone body metabolic process (GO:0046950) | 4.38686904 |
12 | central nervous system myelination (GO:0022010) | 4.36473428 |
13 | axon ensheathment in central nervous system (GO:0032291) | 4.36473428 |
14 | erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221) | 4.11881438 |
15 | L-phenylalanine metabolic process (GO:0006558) | 4.11881438 |
16 | intraciliary transport (GO:0042073) | 3.99746289 |
17 | regulation of acetyl-CoA biosynthetic process from pyruvate (GO:0010510) | 3.89053447 |
18 | exocrine pancreas development (GO:0031017) | 3.86398407 |
19 | ketone body metabolic process (GO:1902224) | 3.78426162 |
20 | endocrine pancreas development (GO:0031018) | 3.78156294 |
21 | ER-associated ubiquitin-dependent protein catabolic process (GO:0030433) | 3.63927289 |
22 | regulation of acyl-CoA biosynthetic process (GO:0050812) | 3.58573896 |
23 | eye photoreceptor cell differentiation (GO:0001754) | 3.57515566 |
24 | photoreceptor cell differentiation (GO:0046530) | 3.57515566 |
25 | regulation of hexokinase activity (GO:1903299) | 3.57127213 |
26 | regulation of glucokinase activity (GO:0033131) | 3.57127213 |
27 | maintenance of protein localization in endoplasmic reticulum (GO:0035437) | 3.47222675 |
28 | protein targeting to Golgi (GO:0000042) | 3.45944186 |
29 | retrograde vesicle-mediated transport, Golgi to ER (GO:0006890) | 3.43858962 |
30 | somite rostral/caudal axis specification (GO:0032525) | 3.42790108 |
31 | peptide hormone processing (GO:0016486) | 3.40844311 |
32 | aromatic amino acid family catabolic process (GO:0009074) | 3.36040374 |
33 | intra-Golgi vesicle-mediated transport (GO:0006891) | 3.35831722 |
34 | protein maturation by protein folding (GO:0022417) | 3.33818514 |
35 | protein localization to Golgi apparatus (GO:0034067) | 3.27905671 |
36 | prenylation (GO:0097354) | 3.27391015 |
37 | protein prenylation (GO:0018342) | 3.27391015 |
38 | positive regulation of protein autophosphorylation (GO:0031954) | 3.27124836 |
39 | negative regulation of neurotransmitter secretion (GO:0046929) | 3.22112800 |
40 | magnesium ion transport (GO:0015693) | 3.20322920 |
41 | mitotic sister chromatid cohesion (GO:0007064) | 3.20203304 |
42 | glandular epithelial cell differentiation (GO:0002067) | 3.17086445 |
43 | nonmotile primary cilium assembly (GO:0035058) | 3.16889286 |
44 | positive regulation of histone H3-K4 methylation (GO:0051571) | 3.15077178 |
45 | response to redox state (GO:0051775) | 3.12581249 |
46 | regulation of sulfur metabolic process (GO:0042762) | 3.11941808 |
47 | sequestering of metal ion (GO:0051238) | 3.11239351 |
48 | nucleotide transport (GO:0006862) | 3.10749458 |
49 | nucleoside diphosphate catabolic process (GO:0009134) | 3.10215760 |
50 | response to nitrosative stress (GO:0051409) | 3.05835220 |
51 | positive regulation of cellular amine metabolic process (GO:0033240) | 3.01070227 |
52 | pyrimidine-containing compound transmembrane transport (GO:0072531) | 2.95781320 |
53 | regulation of coenzyme metabolic process (GO:0051196) | 2.95154029 |
54 | regulation of cofactor metabolic process (GO:0051193) | 2.95154029 |
55 | retrograde transport, vesicle recycling within Golgi (GO:0000301) | 2.94830068 |
56 | genitalia morphogenesis (GO:0035112) | 2.92166913 |
57 | monoubiquitinated protein deubiquitination (GO:0035520) | 2.91987450 |
58 | negative regulation of neurotransmitter transport (GO:0051589) | 2.91923580 |
59 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 2.89970409 |
60 | establishment of protein localization to Golgi (GO:0072600) | 2.88033224 |
61 | cilium morphogenesis (GO:0060271) | 2.86906497 |
62 | intestinal cholesterol absorption (GO:0030299) | 2.85151878 |
63 | cholesterol biosynthetic process (GO:0006695) | 2.85037201 |
64 | ER to Golgi vesicle-mediated transport (GO:0006888) | 2.80316556 |
65 | glycerophospholipid catabolic process (GO:0046475) | 2.80260922 |
66 | keratinocyte development (GO:0003334) | 2.80235840 |
67 | protein K11-linked deubiquitination (GO:0035871) | 2.79711626 |
68 | prostate gland growth (GO:0060736) | 2.79540303 |
69 | auditory receptor cell differentiation (GO:0042491) | 2.78809937 |
70 | mannosylation (GO:0097502) | 2.78758851 |
71 | pharyngeal system development (GO:0060037) | 2.76570721 |
72 | neural tube formation (GO:0001841) | 2.76489288 |
73 | preassembly of GPI anchor in ER membrane (GO:0016254) | 2.76305651 |
74 | response to pheromone (GO:0019236) | 2.75315405 |
75 | regulation of meiosis I (GO:0060631) | 2.73576298 |
76 | lipid particle organization (GO:0034389) | 2.71924076 |
77 | vesicle coating (GO:0006901) | 2.70993436 |
78 | mRNA modification (GO:0016556) | 2.70607050 |
79 | peptidyl-cysteine modification (GO:0018198) | 2.70422297 |
80 | creatine metabolic process (GO:0006600) | 2.69466326 |
81 | detection of calcium ion (GO:0005513) | 2.69277421 |
82 | regulation of centriole replication (GO:0046599) | 2.67877972 |
83 | protein N-linked glycosylation via asparagine (GO:0018279) | 2.67561690 |
84 | centriole replication (GO:0007099) | 2.66392279 |
85 | intestinal epithelial cell development (GO:0060576) | 2.66308178 |
86 | non-recombinational repair (GO:0000726) | 2.65499819 |
87 | double-strand break repair via nonhomologous end joining (GO:0006303) | 2.65499819 |
88 | positive regulation of mitotic metaphase/anaphase transition (GO:0045842) | 2.65310863 |
89 | positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101) | 2.65310863 |
90 | positive regulation of mitotic sister chromatid separation (GO:1901970) | 2.65310863 |
91 | GPI anchor metabolic process (GO:0006505) | 2.64918696 |
92 | protein retention in ER lumen (GO:0006621) | 2.64846346 |
93 | tyrosine metabolic process (GO:0006570) | 2.64675401 |
94 | positive regulation of glycolytic process (GO:0045821) | 2.63897869 |
95 | branched-chain amino acid catabolic process (GO:0009083) | 2.62195097 |
96 | dopamine biosynthetic process (GO:0042416) | 2.61843283 |
97 | ribonucleoprotein complex disassembly (GO:0032988) | 2.60945763 |
98 | peptidyl-asparagine modification (GO:0018196) | 2.60809070 |
99 | vascular smooth muscle contraction (GO:0014829) | 2.60777902 |
100 | negative regulation of DNA-dependent DNA replication (GO:2000104) | 2.60331434 |
101 | zinc ion transport (GO:0006829) | 2.59813841 |
102 | nuclear pore complex assembly (GO:0051292) | 2.58718947 |
103 | protein N-linked glycosylation (GO:0006487) | 2.58094551 |
104 | regulation of DNA endoreduplication (GO:0032875) | 2.57769400 |
105 | early endosome to late endosome transport (GO:0045022) | 2.57278331 |
106 | DNA ligation (GO:0006266) | 2.56838987 |
107 | long-chain fatty-acyl-CoA biosynthetic process (GO:0035338) | 2.56791498 |
108 | histone H2A acetylation (GO:0043968) | 2.56707564 |
109 | activation of signaling protein activity involved in unfolded protein response (GO:0006987) | 2.56518531 |
110 | epithelial cilium movement (GO:0003351) | 2.56358994 |
111 | regulation of type B pancreatic cell apoptotic process (GO:2000674) | 2.55102874 |
112 | single strand break repair (GO:0000012) | 2.54726845 |
113 | coenzyme catabolic process (GO:0009109) | 2.54387426 |
114 | GPI anchor biosynthetic process (GO:0006506) | 2.53742540 |
115 | fucose metabolic process (GO:0006004) | 2.53707264 |
116 | DNA double-strand break processing (GO:0000729) | 2.53210816 |
117 | regulation of protein glycosylation (GO:0060049) | 2.49395546 |
118 | negative regulation of JUN kinase activity (GO:0043508) | 2.49383263 |
119 | myelination (GO:0042552) | 2.49212251 |
120 | replication fork processing (GO:0031297) | 2.47972763 |
121 | response to dietary excess (GO:0002021) | 2.47695869 |
122 | water-soluble vitamin biosynthetic process (GO:0042364) | 2.47186789 |
123 | protein localization to cilium (GO:0061512) | 2.46553247 |
124 | tryptophan metabolic process (GO:0006568) | 2.46073141 |
125 | ensheathment of neurons (GO:0007272) | 2.46004893 |
126 | axon ensheathment (GO:0008366) | 2.46004893 |
127 | cellular glucuronidation (GO:0052695) | 2.45958590 |
128 | apical protein localization (GO:0045176) | 2.45572476 |
129 | very long-chain fatty acid metabolic process (GO:0000038) | 2.45364801 |
130 | aromatic amino acid family metabolic process (GO:0009072) | 2.45300270 |
131 | uronic acid metabolic process (GO:0006063) | 2.44341995 |
132 | glucuronate metabolic process (GO:0019585) | 2.44341995 |
133 | fatty-acyl-CoA biosynthetic process (GO:0046949) | 2.44302849 |
134 | positive regulation of growth hormone secretion (GO:0060124) | 2.43802638 |
135 | positive regulation of insulin secretion (GO:0032024) | 2.43256957 |
136 | axoneme assembly (GO:0035082) | 2.43253290 |
137 | nuclear pore organization (GO:0006999) | 2.42862065 |
138 | regulation of beta-amyloid formation (GO:1902003) | 2.42817754 |
139 | lactate metabolic process (GO:0006089) | 2.42334245 |
140 | asymmetric protein localization (GO:0008105) | 2.41913226 |
141 | presynaptic membrane assembly (GO:0097105) | 2.40190384 |
142 | fatty-acyl-CoA metabolic process (GO:0035337) | 2.39503020 |
143 | regulation of Golgi to plasma membrane protein transport (GO:0042996) | 2.38865076 |
144 | sterol biosynthetic process (GO:0016126) | 2.37294501 |
145 | branched-chain amino acid metabolic process (GO:0009081) | 2.36960922 |
146 | purine ribonucleoside bisphosphate metabolic process (GO:0034035) | 2.35779735 |
147 | 3-phosphoadenosine 5-phosphosulfate metabolic process (GO:0050427) | 2.35779735 |
148 | type B pancreatic cell development (GO:0003323) | 2.35703962 |
149 | pancreas development (GO:0031016) | 2.35521112 |
150 | oligodendrocyte differentiation (GO:0048709) | 2.35320159 |
151 | microtubule anchoring (GO:0034453) | 2.35047135 |
152 | C-terminal protein lipidation (GO:0006501) | 2.34830780 |
153 | hormone catabolic process (GO:0042447) | 2.34715055 |
154 | regulation of ER to Golgi vesicle-mediated transport (GO:0060628) | 2.34512878 |
155 | positive regulation of nuclease activity (GO:0032075) | 2.34329447 |
156 | negative regulation of digestive system process (GO:0060457) | 2.33914616 |
157 | platelet dense granule organization (GO:0060155) | 2.33542415 |
158 | acrosome assembly (GO:0001675) | 2.33443882 |
159 | mitotic G2 DNA damage checkpoint (GO:0007095) | 2.33127265 |
160 | ether lipid metabolic process (GO:0046485) | 2.32580243 |
161 | regulation of calcineurin-NFAT signaling cascade (GO:0070884) | 2.32338822 |
162 | aldehyde catabolic process (GO:0046185) | 2.31639242 |
163 | telomere maintenance via telomerase (GO:0007004) | 2.31527636 |
164 | Sertoli cell development (GO:0060009) | 2.30912185 |
165 | succinate metabolic process (GO:0006105) | 2.30639879 |
166 | UDP-N-acetylglucosamine metabolic process (GO:0006047) | 2.30500010 |
167 | organelle disassembly (GO:1903008) | 2.29726396 |
168 | indolalkylamine metabolic process (GO:0006586) | 2.27739645 |
169 | intra-S DNA damage checkpoint (GO:0031573) | 2.26790994 |
170 | regulation of catecholamine metabolic process (GO:0042069) | 2.26694903 |
171 | regulation of dopamine metabolic process (GO:0042053) | 2.26694903 |
172 | xenobiotic catabolic process (GO:0042178) | 2.26355632 |
173 | pteridine-containing compound biosynthetic process (GO:0042559) | 2.25095617 |
174 | long-chain fatty-acyl-CoA metabolic process (GO:0035336) | 2.24993262 |
175 | thioester biosynthetic process (GO:0035384) | 2.24565622 |
176 | regulation of acrosome reaction (GO:0060046) | 2.24432158 |
Rank | Gene Set | Z-score |
---|---|---|
1 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 3.25500614 |
2 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 3.09307559 |
3 | GBX2_23144817_ChIP-Seq_PC3_Human | 2.95490191 |
4 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 2.70108029 |
5 | TAF15_26573619_Chip-Seq_HEK293_Human | 2.62212768 |
6 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 2.59918942 |
7 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.26834314 |
8 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 2.20527120 |
9 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 2.19206958 |
10 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.18248431 |
11 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 2.15149340 |
12 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 2.08505396 |
13 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 2.06312995 |
14 | VDR_22108803_ChIP-Seq_LS180_Human | 2.01866524 |
15 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 2.00358407 |
16 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 1.93875593 |
17 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.91514624 |
18 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.90547126 |
19 | ESR1_17901129_ChIP-ChIP_LIVER_Mouse | 1.83669823 |
20 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.77573398 |
21 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.74951854 |
22 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.73862870 |
23 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.72256421 |
24 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.72061264 |
25 | FUS_26573619_Chip-Seq_HEK293_Human | 1.69703667 |
26 | P300_19829295_ChIP-Seq_ESCs_Human | 1.68149406 |
27 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 1.67068585 |
28 | GATA1_22025678_ChIP-Seq_K562_Human | 1.64298671 |
29 | KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 1.60913771 |
30 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.59096851 |
31 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.58130815 |
32 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.57826979 |
33 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.56286180 |
34 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.55927161 |
35 | PRDM5_23873026_ChIP-Seq_MEFs_Mouse | 1.55347777 |
36 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.54823726 |
37 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 1.51471495 |
38 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.51254872 |
39 | LXR_22158963_ChIP-Seq_LIVER_Mouse | 1.50966050 |
40 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 1.48861960 |
41 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 1.46437798 |
42 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.46365559 |
43 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 1.46146046 |
44 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.45060234 |
45 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.44550389 |
46 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 1.44251721 |
47 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.44214797 |
48 | ZNF217_24962896_ChIP-Seq_MCF-7_Human | 1.43894034 |
49 | RXR_22158963_ChIP-Seq_LIVER_Mouse | 1.43467339 |
50 | HTT_18923047_ChIP-ChIP_STHdh_Human | 1.41409226 |
51 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.40400404 |
52 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.40400404 |
53 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.40233684 |
54 | RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse | 1.39249707 |
55 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.39027099 |
56 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 1.38890720 |
57 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 1.38866567 |
58 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.38129297 |
59 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.37751091 |
60 | FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human | 1.35734930 |
61 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.34148539 |
62 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.34122401 |
63 | CDX2_22108803_ChIP-Seq_LS180_Human | 1.33682403 |
64 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.33332735 |
65 | P53_22387025_ChIP-Seq_ESCs_Mouse | 1.32759625 |
66 | FOXO1_23066095_ChIP-Seq_LIVER_Mouse | 1.32721584 |
67 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.31683035 |
68 | NRF2_20460467_ChIP-Seq_MEFs_Mouse | 1.30914609 |
69 | NFE2L2_20460467_ChIP-Seq_MEFs_Mouse | 1.30914609 |
70 | FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 1.30773028 |
71 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 1.30063568 |
72 | STAT3_23295773_ChIP-Seq_U87_Human | 1.29340384 |
73 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.28816070 |
74 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.27137864 |
75 | TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse | 1.26524699 |
76 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 1.25974586 |
77 | SUZ12_18555785_Chip-Seq_ESCs_Mouse | 1.23771723 |
78 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 1.23376814 |
79 | HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse | 1.22639887 |
80 | CMYC_18555785_Chip-Seq_ESCs_Mouse | 1.21778767 |
81 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.21635593 |
82 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.21553371 |
83 | * SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.21551982 |
84 | TCF4_22108803_ChIP-Seq_LS180_Human | 1.21140674 |
85 | STAT3_18555785_Chip-Seq_ESCs_Mouse | 1.20538207 |
86 | SALL4_22934838_ChIP-ChIP_CD34+_Human | 1.19888515 |
87 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.19637529 |
88 | TAL1_26923725_Chip-Seq_HPCs_Mouse | 1.19389930 |
89 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.19215268 |
90 | P300_18555785_Chip-Seq_ESCs_Mouse | 1.18847787 |
91 | TCF4_23295773_ChIP-Seq_U87_Human | 1.17872918 |
92 | NR3C1_23031785_ChIP-Seq_PC12_Mouse | 1.17712665 |
93 | AR_25329375_ChIP-Seq_VCAP_Human | 1.17215118 |
94 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.16460711 |
95 | WT1_19549856_ChIP-ChIP_CCG9911_Human | 1.16380950 |
96 | EWS_26573619_Chip-Seq_HEK293_Human | 1.15399178 |
97 | CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse | 1.14756731 |
98 | AR_21915096_ChIP-Seq_LNCaP-1F5_Human | 1.14568259 |
99 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.14530822 |
100 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.14530822 |
101 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 1.13347315 |
102 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.13270173 |
103 | ESR1_22446102_ChIP-Seq_UTERUS_Mouse | 1.12817683 |
104 | E2F1_18555785_Chip-Seq_ESCs_Mouse | 1.12267455 |
105 | FOXA1_25552417_ChIP-Seq_VCAP_Human | 1.12021026 |
106 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.11055604 |
107 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 1.10416559 |
108 | NMYC_18555785_Chip-Seq_ESCs_Mouse | 1.10236863 |
109 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 1.10144683 |
110 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 1.09627495 |
111 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 1.09526818 |
112 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.09469764 |
113 | RUNX1_27457419_Chip-Seq_LIVER_Mouse | 1.09187083 |
114 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.09166331 |
115 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 1.07349451 |
116 | SOX2_18555785_Chip-Seq_ESCs_Mouse | 1.07025307 |
117 | EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse | 1.06788724 |
118 | OCT4_21477851_ChIP-Seq_ESCs_Mouse | 1.06780193 |
119 | TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.06716258 |
120 | FOXM1_26456572_ChIP-Seq_MCF-7_Human | 1.06311561 |
121 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 1.05902615 |
122 | FOXA1_26743006_Chip-Seq_LNCaP-abl_Human | 1.05785572 |
123 | SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 1.05595406 |
124 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.05581494 |
125 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 1.05435553 |
126 | RUNX2_22187159_ChIP-Seq_PCA_Human | 1.05337151 |
127 | LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.05199718 |
128 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 1.04937636 |
129 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 1.04455822 |
130 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 1.04310887 |
131 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.03811764 |
132 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.03739411 |
133 | KDM2B_26808549_Chip-Seq_REH_Human | 1.03203122 |
134 | FLI1_21867929_ChIP-Seq_TH2_Mouse | 1.01324303 |
135 | OCT4_18555785_Chip-Seq_ESCs_Mouse | 1.01233485 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0008057_abnormal_DNA_replication | 4.16609646 |
2 | MP0002139_abnormal_hepatobiliary_system | 3.51666253 |
3 | MP0004043_abnormal_pH_regulation | 3.27762719 |
4 | MP0003183_abnormal_peptide_metabolism | 3.16176357 |
5 | MP0003195_calcinosis | 3.11789815 |
6 | MP0005365_abnormal_bile_salt | 2.98863150 |
7 | MP0005646_abnormal_pituitary_gland | 2.97945758 |
8 | MP0005379_endocrine/exocrine_gland_phen | 2.83527060 |
9 | MP0003787_abnormal_imprinting | 2.83339010 |
10 | MP0009780_abnormal_chondrocyte_physiolo | 2.79601958 |
11 | MP0008877_abnormal_DNA_methylation | 2.79287132 |
12 | MP0010386_abnormal_urinary_bladder | 2.55388460 |
13 | MP0003890_abnormal_embryonic-extraembry | 2.46671051 |
14 | MP0002837_dystrophic_cardiac_calcinosis | 2.40867715 |
15 | MP0003122_maternal_imprinting | 2.40467424 |
16 | MP0005645_abnormal_hypothalamus_physiol | 2.38609936 |
17 | MP0005220_abnormal_exocrine_pancreas | 2.35076283 |
18 | MP0010234_abnormal_vibrissa_follicle | 2.28381528 |
19 | MP0000013_abnormal_adipose_tissue | 2.25684326 |
20 | MP0008058_abnormal_DNA_repair | 2.25003835 |
21 | MP0001666_abnormal_nutrient_absorption | 2.21579165 |
22 | MP0002693_abnormal_pancreas_physiology | 2.19932102 |
23 | MP0005085_abnormal_gallbladder_physiolo | 2.18100198 |
24 | MP0000920_abnormal_myelination | 2.12693831 |
25 | MP0000427_abnormal_hair_cycle | 2.11755645 |
26 | MP0003868_abnormal_feces_composition | 2.11515989 |
27 | MP0008875_abnormal_xenobiotic_pharmacok | 2.10989025 |
28 | MP0000569_abnormal_digit_pigmentation | 2.10557797 |
29 | MP0006054_spinal_hemorrhage | 2.07363528 |
30 | MP0001944_abnormal_pancreas_morphology | 2.07145762 |
31 | MP0006072_abnormal_retinal_apoptosis | 1.91251366 |
32 | MP0003121_genomic_imprinting | 1.89263108 |
33 | MP0000566_synostosis | 1.84478150 |
34 | MP0004264_abnormal_extraembryonic_tissu | 1.74709730 |
35 | MP0003941_abnormal_skin_development | 1.74358316 |
36 | MP0003806_abnormal_nucleotide_metabolis | 1.74017981 |
37 | MP0005367_renal/urinary_system_phenotyp | 1.73277627 |
38 | MP0000516_abnormal_urinary_system | 1.73277627 |
39 | MP0010678_abnormal_skin_adnexa | 1.72839229 |
40 | MP0005551_abnormal_eye_electrophysiolog | 1.66600354 |
41 | MP0003880_abnormal_central_pattern | 1.64659901 |
42 | MP0002876_abnormal_thyroid_physiology | 1.62518911 |
43 | MP0005408_hypopigmentation | 1.61554882 |
44 | MP0005360_urolithiasis | 1.57151902 |
45 | MP0004147_increased_porphyrin_level | 1.54538366 |
46 | MP0003718_maternal_effect | 1.54359886 |
47 | MP0002009_preneoplasia | 1.53967177 |
48 | MP0000613_abnormal_salivary_gland | 1.53888844 |
49 | MP0010352_gastrointestinal_tract_polyps | 1.50967908 |
50 | MP0004215_abnormal_myocardial_fiber | 1.50303550 |
51 | MP0000462_abnormal_digestive_system | 1.48568701 |
52 | MP0009697_abnormal_copulation | 1.47750102 |
53 | MP0003252_abnormal_bile_duct | 1.43754197 |
54 | MP0000383_abnormal_hair_follicle | 1.41553805 |
55 | MP0002078_abnormal_glucose_homeostasis | 1.39863386 |
56 | MP0003690_abnormal_glial_cell | 1.39562731 |
57 | MP0004084_abnormal_cardiac_muscle | 1.35622323 |
58 | MP0005310_abnormal_salivary_gland | 1.35442647 |
59 | MP0005647_abnormal_sex_gland | 1.34390671 |
60 | MP0005248_abnormal_Harderian_gland | 1.34370129 |
61 | MP0001905_abnormal_dopamine_level | 1.32060643 |
62 | MP0005332_abnormal_amino_acid | 1.31894525 |
63 | MP0000631_abnormal_neuroendocrine_gland | 1.31411567 |
64 | MP0001765_abnormal_ion_homeostasis | 1.31009404 |
65 | MP0005171_absent_coat_pigmentation | 1.28248104 |
66 | MP0000003_abnormal_adipose_tissue | 1.26897120 |
67 | MP0002163_abnormal_gland_morphology | 1.25255071 |
68 | MP0005084_abnormal_gallbladder_morpholo | 1.23682897 |
69 | MP0005083_abnormal_biliary_tract | 1.21882912 |
70 | MP0002166_altered_tumor_susceptibility | 1.21879065 |
71 | MP0002118_abnormal_lipid_homeostasis | 1.21410428 |
72 | MP0001346_abnormal_lacrimal_gland | 1.21332329 |
73 | MP0005253_abnormal_eye_physiology | 1.20629507 |
74 | MP0008775_abnormal_heart_ventricle | 1.18981066 |
75 | MP0004145_abnormal_muscle_electrophysio | 1.17408575 |
76 | MP0002272_abnormal_nervous_system | 1.17163846 |
77 | MP0003959_abnormal_lean_body | 1.16532892 |
78 | MP0002229_neurodegeneration | 1.16055674 |
79 | MP0010094_abnormal_chromosome_stability | 1.15991924 |
80 | MP0005409_darkened_coat_color | 1.15919166 |
81 | MP0004885_abnormal_endolymph | 1.15046073 |
82 | MP0001502_abnormal_circadian_rhythm | 1.14408330 |
83 | MP0004270_analgesia | 1.13126856 |
84 | MP0000230_abnormal_systemic_arterial | 1.12498195 |
85 | MP0003283_abnormal_digestive_organ | 1.12362274 |
86 | MP0003786_premature_aging | 1.12088396 |
87 | MP0004742_abnormal_vestibular_system | 1.11274293 |
88 | MP0009643_abnormal_urine_homeostasis | 1.11107169 |
89 | MP0002877_abnormal_melanocyte_morpholog | 1.10209755 |
90 | MP0002909_abnormal_adrenal_gland | 1.09966556 |
91 | MP0000639_abnormal_adrenal_gland | 1.09250904 |
92 | MP0001486_abnormal_startle_reflex | 1.08452298 |
93 | MP0005058_abnormal_lysosome_morphology | 1.08129085 |
94 | MP0005187_abnormal_penis_morphology | 1.06533488 |
95 | MP0002234_abnormal_pharynx_morphology | 1.03042694 |
96 | MP0005636_abnormal_mineral_homeostasis | 1.02386187 |
97 | MP0006036_abnormal_mitochondrial_physio | 1.02149975 |
98 | MP0001764_abnormal_homeostasis | 1.00753337 |
99 | MP0001529_abnormal_vocalization | 0.98981925 |
100 | MP0000647_abnormal_sebaceous_gland | 0.98674000 |
101 | MP0001984_abnormal_olfaction | 0.97613457 |
102 | MP0003634_abnormal_glial_cell | 0.96258104 |
103 | MP0001661_extended_life_span | 0.94486836 |
104 | MP0008789_abnormal_olfactory_epithelium | 0.94337083 |
105 | MP0000372_irregular_coat_pigmentation | 0.94225469 |
106 | MP0005535_abnormal_body_temperature | 0.93508207 |
107 | MP0003186_abnormal_redox_activity | 0.92390593 |
108 | MP0008995_early_reproductive_senescence | 0.92070264 |
109 | MP0004134_abnormal_chest_morphology | 0.90618326 |
110 | MP0004484_altered_response_of | 0.89182884 |
111 | MP0001485_abnormal_pinna_reflex | 0.86913771 |
112 | MP0003953_abnormal_hormone_level | 0.86870575 |
113 | MP0002295_abnormal_pulmonary_circulatio | 0.85797804 |
114 | MP0004142_abnormal_muscle_tone | 0.85544597 |
115 | MP0010329_abnormal_lipoprotein_level | 0.84940543 |
116 | MP0000678_abnormal_parathyroid_gland | 0.84275100 |
117 | MP0008007_abnormal_cellular_replicative | 0.84263754 |
118 | MP0001664_abnormal_digestion | 0.83605380 |
119 | MP0002928_abnormal_bile_duct | 0.82971482 |
120 | MP0005395_other_phenotype | 0.82797073 |
121 | MP0002396_abnormal_hematopoietic_system | 0.81678238 |
122 | MP0001986_abnormal_taste_sensitivity | 0.81354770 |
123 | MP0002938_white_spotting | 0.80796440 |
124 | MP0009703_decreased_birth_body | 0.80417999 |
125 | MP0002006_tumorigenesis | 0.80258190 |
126 | MP0002269_muscular_atrophy | 0.79707381 |
127 | MP0003011_delayed_dark_adaptation | 0.79700086 |
128 | MP0009115_abnormal_fat_cell | 0.79138642 |
129 | MP0002638_abnormal_pupillary_reflex | 0.78655845 |
130 | MP0004019_abnormal_vitamin_homeostasis | 0.78557401 |
131 | MP0002971_abnormal_brown_adipose | 0.78146057 |
132 | MP0003937_abnormal_limbs/digits/tail_de | 0.77100471 |
133 | MP0003567_abnormal_fetal_cardiomyocyte | 0.76959876 |
134 | MP0001756_abnormal_urination | 0.75616897 |
135 | MP0003943_abnormal_hepatobiliary_system | 0.75560133 |
136 | MP0010307_abnormal_tumor_latency | 0.74387965 |
137 | MP0003656_abnormal_erythrocyte_physiolo | 0.73745074 |
138 | MP0003172_abnormal_lysosome_physiology | 0.72983747 |
139 | MP0004036_abnormal_muscle_relaxation | 0.72973476 |
140 | MP0005410_abnormal_fertilization | 0.72715573 |
141 | MP0003632_abnormal_nervous_system | 0.72419265 |
142 | MP0003950_abnormal_plasma_membrane | 0.71503117 |
143 | MP0005266_abnormal_metabolism | 0.70658655 |
144 | MP0005334_abnormal_fat_pad | 0.68835690 |
145 | MP0005394_taste/olfaction_phenotype | 0.68827290 |
146 | MP0004085_abnormal_heartbeat | 0.68669618 |
147 | MP0005195_abnormal_posterior_eye | 0.67911462 |
148 | MP0000538_abnormal_urinary_bladder | 0.67298919 |
149 | MP0002572_abnormal_emotion/affect_behav | 0.66890929 |
150 | MP0003329_amyloid_beta_deposits | 0.66833566 |
151 | MP0001324_abnormal_eye_pigmentation | 0.66612598 |
152 | MP0002090_abnormal_vision | 0.65286756 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Hypoglycemic seizures (HP:0002173) | 4.85381110 |
2 | Hyperinsulinemic hypoglycemia (HP:0000825) | 4.81338961 |
3 | Symptomatic seizures (HP:0011145) | 4.44294893 |
4 | Hypoglycemic coma (HP:0001325) | 4.43185562 |
5 | Abnormality of aromatic amino acid family metabolism (HP:0004338) | 4.30106081 |
6 | Papillary thyroid carcinoma (HP:0002895) | 4.05180958 |
7 | Conjugated hyperbilirubinemia (HP:0002908) | 3.41951382 |
8 | Pancreatic islet-cell hyperplasia (HP:0004510) | 3.41282914 |
9 | Abnormality of the intrinsic pathway (HP:0010989) | 3.36606065 |
10 | Ketoacidosis (HP:0001993) | 3.19648932 |
11 | Intrahepatic cholestasis (HP:0001406) | 3.18986739 |
12 | Elevated circulating parathyroid hormone (PTH) level (HP:0003165) | 3.15980168 |
13 | Volvulus (HP:0002580) | 3.10159697 |
14 | Generalized aminoaciduria (HP:0002909) | 3.08337083 |
15 | Abnormality of the pancreatic islet cells (HP:0006476) | 3.08309508 |
16 | Abnormality of endocrine pancreas physiology (HP:0012093) | 3.08309508 |
17 | Abnormality of vitamin B metabolism (HP:0004340) | 2.98700886 |
18 | Thyroid carcinoma (HP:0002890) | 2.97977587 |
19 | Hypothermia (HP:0002045) | 2.97796009 |
20 | Prolonged partial thromboplastin time (HP:0003645) | 2.97365442 |
21 | Abnormality of methionine metabolism (HP:0010901) | 2.90472949 |
22 | Ketosis (HP:0001946) | 2.90255161 |
23 | Abnormality of the renal cortex (HP:0011035) | 2.82596605 |
24 | Degeneration of the lateral corticospinal tracts (HP:0002314) | 2.79779110 |
25 | Atrophy/Degeneration involving the corticospinal tracts (HP:0007372) | 2.79779110 |
26 | Congenital sensorineural hearing impairment (HP:0008527) | 2.79253696 |
27 | Hyperglycemia (HP:0003074) | 2.77530387 |
28 | Neurofibrillary tangles (HP:0002185) | 2.75688220 |
29 | Decreased circulating renin level (HP:0003351) | 2.72169140 |
30 | Increased serum pyruvate (HP:0003542) | 2.69778248 |
31 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 2.67884796 |
32 | Fat malabsorption (HP:0002630) | 2.62342263 |
33 | Exercise-induced muscle cramps (HP:0003710) | 2.61290269 |
34 | Tubulointerstitial nephritis (HP:0001970) | 2.58168114 |
35 | Calf muscle hypertrophy (HP:0008981) | 2.53448697 |
36 | Abnormal biliary tract morphology (HP:0012440) | 2.53150273 |
37 | Proximal tubulopathy (HP:0000114) | 2.47082306 |
38 | Abnormality of glycolysis (HP:0004366) | 2.46715492 |
39 | Abnormal pancreas size (HP:0012094) | 2.44246589 |
40 | Abnormal protein glycosylation (HP:0012346) | 2.43964546 |
41 | Abnormal glycosylation (HP:0012345) | 2.43964546 |
42 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 2.43964546 |
43 | Abnormal protein N-linked glycosylation (HP:0012347) | 2.43964546 |
44 | Abnormality of the common coagulation pathway (HP:0010990) | 2.43343062 |
45 | Abnormality of vitamin metabolism (HP:0100508) | 2.42952408 |
46 | Abnormality of the vitamin B12 metabolism (HP:0004341) | 2.35748386 |
47 | Anteriorly placed anus (HP:0001545) | 2.34777217 |
48 | Insulin-resistant diabetes mellitus (HP:0000831) | 2.34385765 |
49 | Medial flaring of the eyebrow (HP:0010747) | 2.33929811 |
50 | Parakeratosis (HP:0001036) | 2.33382438 |
51 | Abnormality of calcium-phosphate metabolism (HP:0100530) | 2.30436625 |
52 | Hyperkalemia (HP:0002153) | 2.30216997 |
53 | Biliary tract neoplasm (HP:0100574) | 2.29788773 |
54 | Hyperglycinuria (HP:0003108) | 2.29417618 |
55 | Steatorrhea (HP:0002570) | 2.29257746 |
56 | Muscle hypertrophy of the lower extremities (HP:0008968) | 2.25158253 |
57 | Colon cancer (HP:0003003) | 2.24746489 |
58 | Alacrima (HP:0000522) | 2.24656018 |
59 | Neuroendocrine neoplasm (HP:0100634) | 2.24198189 |
60 | Hypomagnesemia (HP:0002917) | 2.22894489 |
61 | Type I transferrin isoform profile (HP:0003642) | 2.22480173 |
62 | Retinal dysplasia (HP:0007973) | 2.21650578 |
63 | Retinal atrophy (HP:0001105) | 2.20432843 |
64 | Neoplasm of the adrenal gland (HP:0100631) | 2.19904240 |
65 | Vacuolated lymphocytes (HP:0001922) | 2.18100098 |
66 | Large for gestational age (HP:0001520) | 2.18060771 |
67 | Hyperglycinemia (HP:0002154) | 2.17610710 |
68 | Acute encephalopathy (HP:0006846) | 2.16925088 |
69 | Congenital primary aphakia (HP:0007707) | 2.11509307 |
70 | Overlapping toe (HP:0001845) | 2.11196352 |
71 | Hypokalemia (HP:0002900) | 2.10882032 |
72 | Acute necrotizing encephalopathy (HP:0006965) | 2.10729446 |
73 | Pheochromocytoma (HP:0002666) | 2.09959507 |
74 | EEG with generalized epileptiform discharges (HP:0011198) | 2.09718821 |
75 | Epidermoid cyst (HP:0200040) | 2.09420990 |
76 | Dysostosis multiplex (HP:0000943) | 2.08619395 |
77 | Enlarged kidneys (HP:0000105) | 2.08617603 |
78 | Hyperlipoproteinemia (HP:0010980) | 2.07754429 |
79 | Barrel-shaped chest (HP:0001552) | 2.07291313 |
80 | Methylmalonic aciduria (HP:0012120) | 2.06970229 |
81 | Hepatoblastoma (HP:0002884) | 2.06363555 |
82 | Epileptiform EEG discharges (HP:0011182) | 2.05694415 |
83 | Vaginal atresia (HP:0000148) | 2.05623750 |
84 | Decreased lacrimation (HP:0000633) | 2.05542124 |
85 | Hypoplasia of the uterus (HP:0000013) | 2.03960173 |
86 | Renal cortical cysts (HP:0000803) | 2.02784981 |
87 | Gait imbalance (HP:0002141) | 2.02304484 |
88 | Abnormality of glycine metabolism (HP:0010895) | 2.01772079 |
89 | Abnormality of serine family amino acid metabolism (HP:0010894) | 2.01772079 |
90 | Neoplasm of the small intestine (HP:0100833) | 2.01651531 |
91 | Abnormality of urine glucose concentration (HP:0011016) | 2.01422924 |
92 | Glycosuria (HP:0003076) | 2.01422924 |
93 | Progressive neurologic deterioration (HP:0002344) | 2.00253583 |
94 | Methylmalonic acidemia (HP:0002912) | 1.98646120 |
95 | Hypsarrhythmia (HP:0002521) | 1.97795708 |
96 | Genital tract atresia (HP:0001827) | 1.97429065 |
97 | 3-Methylglutaconic aciduria (HP:0003535) | 1.97233902 |
98 | Increased CSF lactate (HP:0002490) | 1.96220663 |
99 | Hypoplastic labia majora (HP:0000059) | 1.95683683 |
100 | Abnormality of potassium homeostasis (HP:0011042) | 1.95386665 |
101 | Acanthocytosis (HP:0001927) | 1.95254792 |
102 | Nephrogenic diabetes insipidus (HP:0009806) | 1.94952129 |
103 | Hypobetalipoproteinemia (HP:0003563) | 1.94504033 |
104 | Poor coordination (HP:0002370) | 1.93183073 |
105 | Morphological abnormality of the inner ear (HP:0011390) | 1.91309674 |
106 | Abnormality of the renal medulla (HP:0100957) | 1.90691761 |
107 | Abnormality of chromosome stability (HP:0003220) | 1.90431250 |
108 | Abnormality of chloride homeostasis (HP:0011422) | 1.89750730 |
109 | Right ventricular cardiomyopathy (HP:0011663) | 1.88261866 |
110 | Ovarian neoplasm (HP:0100615) | 1.88081010 |
111 | Oligodactyly (hands) (HP:0001180) | 1.87012109 |
112 | Rhabdomyosarcoma (HP:0002859) | 1.86194881 |
113 | Abnormal mitochondria in muscle tissue (HP:0008316) | 1.85101173 |
114 | Abnormality of renin-angiotensin system (HP:0000847) | 1.84842695 |
115 | Hepatic necrosis (HP:0002605) | 1.83953081 |
116 | Abnormality of cochlea (HP:0000375) | 1.83827521 |
117 | Pancreatic fibrosis (HP:0100732) | 1.83750328 |
118 | Cerebral edema (HP:0002181) | 1.82177749 |
119 | Progressive macrocephaly (HP:0004481) | 1.82054489 |
120 | Chronic hepatic failure (HP:0100626) | 1.81586608 |
121 | Gaze-evoked nystagmus (HP:0000640) | 1.80944879 |
122 | Nephronophthisis (HP:0000090) | 1.80710499 |
123 | Fair hair (HP:0002286) | 1.79774517 |
124 | Reduced antithrombin III activity (HP:0001976) | 1.79281214 |
125 | Intestinal atresia (HP:0011100) | 1.79247100 |
126 | Cerebral inclusion bodies (HP:0100314) | 1.78906919 |
127 | Bifid tongue (HP:0010297) | 1.78821322 |
128 | Protuberant abdomen (HP:0001538) | 1.78181697 |
129 | Pancreatic cysts (HP:0001737) | 1.78034440 |
130 | Labial hypoplasia (HP:0000066) | 1.75719855 |
131 | Abnormal hair whorl (HP:0010721) | 1.74470974 |
132 | White forelock (HP:0002211) | 1.74418304 |
133 | Abnormality of the labia minora (HP:0012880) | 1.74290344 |
134 | Mitochondrial inheritance (HP:0001427) | 1.73559369 |
135 | Patchy hypopigmentation of hair (HP:0011365) | 1.73228459 |
136 | Osteomalacia (HP:0002749) | 1.73227543 |
137 | Abnormality of the labia majora (HP:0012881) | 1.73127436 |
138 | Xanthomatosis (HP:0000991) | 1.73016994 |
139 | Limb hypertonia (HP:0002509) | 1.72722624 |
140 | Abnormality of long-chain fatty-acid metabolism (HP:0010964) | 1.72287878 |
141 | Disproportionate short-trunk short stature (HP:0003521) | 1.72266091 |
142 | Growth hormone deficiency (HP:0000824) | 1.72248981 |
143 | Abnormal foot bone ossification (HP:0010675) | 1.71791380 |
144 | Metabolic acidosis (HP:0001942) | 1.71179546 |
145 | Exocrine pancreatic insufficiency (HP:0001738) | 1.70824519 |
146 | Blue irides (HP:0000635) | 1.70252586 |
147 | Supernumerary spleens (HP:0009799) | 1.69889073 |
148 | Abnormality of serum amino acid levels (HP:0003112) | 1.69870374 |
149 | Muscular hypotonia of the trunk (HP:0008936) | 1.69526863 |
150 | Abnormality of magnesium homeostasis (HP:0004921) | 1.68736725 |
151 | Mucopolysacchariduria (HP:0008155) | 1.67623292 |
152 | Urinary glycosaminoglycan excretion (HP:0003541) | 1.67623292 |
153 | Hyperventilation (HP:0002883) | 1.67441943 |
154 | Widely patent fontanelles and sutures (HP:0004492) | 1.67159374 |
155 | Septo-optic dysplasia (HP:0100842) | 1.65536382 |
156 | Increased hepatocellular lipid droplets (HP:0006565) | 1.65086352 |
157 | Medulloblastoma (HP:0002885) | 1.64765872 |
158 | Renal Fanconi syndrome (HP:0001994) | 1.63894159 |
159 | Agitation (HP:0000713) | 1.63649695 |
Rank | Gene Set | Z-score |
---|---|---|
1 | INSRR | 4.73341421 |
2 | STK39 | 3.70325689 |
3 | MAPK15 | 3.66604948 |
4 | FRK | 3.45220838 |
5 | TAOK3 | 3.16372398 |
6 | ERBB3 | 2.78073436 |
7 | AKT3 | 2.70319366 |
8 | WNK4 | 2.45052930 |
9 | CASK | 2.22790434 |
10 | OXSR1 | 2.07643509 |
11 | TRIM28 | 2.01886930 |
12 | TNIK | 1.84566417 |
13 | PIK3CG | 1.79819850 |
14 | MKNK2 | 1.77910042 |
15 | PASK | 1.76149394 |
16 | BCKDK | 1.73713872 |
17 | EIF2AK1 | 1.68677227 |
18 | MAP4K2 | 1.66518202 |
19 | BMPR1B | 1.65463047 |
20 | STK38L | 1.61427312 |
21 | NEK6 | 1.57030718 |
22 | ACVR1B | 1.54001996 |
23 | STK24 | 1.51893380 |
24 | EPHB1 | 1.51260326 |
25 | FGFR3 | 1.45383634 |
26 | IRAK2 | 1.43470424 |
27 | PLK2 | 1.40704855 |
28 | GRK7 | 1.40472263 |
29 | FER | 1.40359899 |
30 | PKN1 | 1.38747364 |
31 | NUAK1 | 1.36480028 |
32 | GRK1 | 1.35796003 |
33 | WNK1 | 1.32224300 |
34 | MKNK1 | 1.30787694 |
35 | NEK9 | 1.27965429 |
36 | MST4 | 1.26589173 |
37 | IRAK1 | 1.25710663 |
38 | MAP3K2 | 1.25104224 |
39 | MAPKAPK5 | 1.24352981 |
40 | WNK3 | 1.18762744 |
41 | UHMK1 | 1.18521136 |
42 | TSSK6 | 1.17742564 |
43 | BCR | 1.16594772 |
44 | PLK3 | 1.16268828 |
45 | ERN1 | 1.15927012 |
46 | STK3 | 1.15192251 |
47 | EIF2AK3 | 1.15150155 |
48 | ADRBK2 | 1.14724941 |
49 | BMPR2 | 1.14311219 |
50 | PBK | 1.13259999 |
51 | HIPK2 | 1.12633598 |
52 | TGFBR1 | 1.12413623 |
53 | PIK3CA | 1.12228881 |
54 | NEK1 | 1.11635317 |
55 | BRD4 | 1.10173735 |
56 | MAP3K12 | 1.09064975 |
57 | TRPM7 | 1.07860259 |
58 | SCYL2 | 1.07522874 |
59 | PRKCE | 1.07390646 |
60 | IRAK3 | 1.04959921 |
61 | CAMK2D | 1.04370541 |
62 | CAMK2B | 1.03426826 |
63 | TTK | 1.03303613 |
64 | MAP3K13 | 1.00733145 |
65 | LATS1 | 1.00681685 |
66 | BRSK2 | 0.98191388 |
67 | PLK4 | 0.95077564 |
68 | EPHA3 | 0.93555210 |
69 | FGFR2 | 0.93415768 |
70 | MET | 0.93072592 |
71 | SGK223 | 0.91469323 |
72 | SGK494 | 0.91469323 |
73 | PRPF4B | 0.88617159 |
74 | SIK1 | 0.81288751 |
75 | IRAK4 | 0.80458034 |
76 | STK16 | 0.79752461 |
77 | FGFR1 | 0.78727334 |
78 | NTRK1 | 0.77850678 |
79 | PRKCQ | 0.76960407 |
80 | MUSK | 0.73103666 |
81 | CSNK1A1L | 0.72750180 |
82 | PRKAA2 | 0.71838017 |
83 | CAMK1G | 0.71682432 |
84 | CDK3 | 0.70385818 |
85 | TAF1 | 0.69105274 |
86 | LMTK2 | 0.68637900 |
87 | OBSCN | 0.68222935 |
88 | ITK | 0.67890519 |
89 | CAMK2G | 0.66640914 |
90 | ATM | 0.66581966 |
91 | NTRK3 | 0.65959539 |
92 | CCNB1 | 0.65847602 |
93 | MAPK13 | 0.65240324 |
94 | ARAF | 0.65085524 |
95 | ZAK | 0.64489777 |
96 | PHKG2 | 0.64476810 |
97 | PHKG1 | 0.64476810 |
98 | MAP3K14 | 0.62082251 |
99 | ERBB4 | 0.61774543 |
100 | CAMK2A | 0.61658534 |
101 | CAMKK2 | 0.61114746 |
102 | PDK2 | 0.60332018 |
103 | PNCK | 0.59619533 |
104 | PRKG1 | 0.59058117 |
105 | MAP2K7 | 0.57023582 |
106 | MYLK | 0.56706236 |
107 | TEC | 0.56674775 |
108 | CSNK1G3 | 0.56550701 |
109 | WEE1 | 0.55597000 |
110 | NLK | 0.55142403 |
111 | CSNK1G2 | 0.54534728 |
112 | YES1 | 0.52540414 |
113 | CAMK1D | 0.52370308 |
114 | CSNK1G1 | 0.51538318 |
115 | TIE1 | 0.51329542 |
116 | MAP3K4 | 0.51218753 |
117 | CSNK1E | 0.49377129 |
118 | EPHA4 | 0.48742078 |
119 | ADRBK1 | 0.48376885 |
120 | DYRK3 | 0.47930823 |
121 | PAK3 | 0.47442561 |
122 | SGK2 | 0.46899204 |
123 | MAPK7 | 0.46603104 |
124 | PRKD3 | 0.45782594 |
125 | KSR1 | 0.45085330 |
126 | PRKD2 | 0.43298366 |
127 | PRKACB | 0.43036348 |
128 | CSNK1A1 | 0.42798356 |
129 | FLT3 | 0.41849568 |
130 | VRK1 | 0.41452313 |
131 | PRKD1 | 0.41417469 |
132 | GSK3A | 0.39724017 |
133 | PRKCG | 0.39704609 |
134 | PRKACA | 0.39388437 |
135 | RPS6KB1 | 0.38244884 |
136 | SRPK1 | 0.38222829 |
137 | SGK1 | 0.37097733 |
138 | CSNK2A2 | 0.36030637 |
139 | PRKCH | 0.35909063 |
140 | IGF1R | 0.35564874 |
141 | CHEK1 | 0.35534958 |
142 | PINK1 | 0.35203416 |
143 | MELK | 0.34992853 |
144 | EIF2AK2 | 0.34691754 |
145 | PRKAA1 | 0.34444670 |
146 | CDC42BPA | 0.34340239 |
147 | PLK1 | 0.33171231 |
148 | JAK1 | 0.31739355 |
149 | SGK3 | 0.31601574 |
150 | NME1 | 0.30124220 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Protein export_Homo sapiens_hsa03060 | 5.66097812 |
2 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 5.03894816 |
3 | Sulfur metabolism_Homo sapiens_hsa00920 | 3.92994500 |
4 | Fatty acid elongation_Homo sapiens_hsa00062 | 2.46509129 |
5 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 2.39758497 |
6 | Steroid biosynthesis_Homo sapiens_hsa00100 | 2.18721386 |
7 | Non-homologous end-joining_Homo sapiens_hsa03450 | 2.16575599 |
8 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 2.12753483 |
9 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 2.12146990 |
10 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.85016909 |
11 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.83729584 |
12 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 1.82416786 |
13 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.79824508 |
14 | Histidine metabolism_Homo sapiens_hsa00340 | 1.78903203 |
15 | Basal transcription factors_Homo sapiens_hsa03022 | 1.75635074 |
16 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 1.69237443 |
17 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 1.68873473 |
18 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.68388040 |
19 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.64005357 |
20 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 1.63176615 |
21 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 1.51571923 |
22 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.50276773 |
23 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 1.46202292 |
24 | Peroxisome_Homo sapiens_hsa04146 | 1.43237659 |
25 | Folate biosynthesis_Homo sapiens_hsa00790 | 1.39633587 |
26 | Insulin secretion_Homo sapiens_hsa04911 | 1.38322336 |
27 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 1.37767540 |
28 | RNA degradation_Homo sapiens_hsa03018 | 1.37546729 |
29 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.35915146 |
30 | ABC transporters_Homo sapiens_hsa02010 | 1.29914403 |
31 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 1.25929363 |
32 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 1.25706073 |
33 | Other glycan degradation_Homo sapiens_hsa00511 | 1.23797683 |
34 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 1.19218628 |
35 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.19084619 |
36 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 1.18230200 |
37 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.16639618 |
38 | Fatty acid degradation_Homo sapiens_hsa00071 | 1.11822923 |
39 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.09460409 |
40 | Cocaine addiction_Homo sapiens_hsa05030 | 1.05424252 |
41 | Pancreatic secretion_Homo sapiens_hsa04972 | 1.05035024 |
42 | Proteasome_Homo sapiens_hsa03050 | 1.05031062 |
43 | Ether lipid metabolism_Homo sapiens_hsa00565 | 1.03507463 |
44 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 1.01095863 |
45 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 1.00857263 |
46 | Fatty acid metabolism_Homo sapiens_hsa01212 | 1.00667481 |
47 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.99595929 |
48 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.98519712 |
49 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.96620954 |
50 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.96347086 |
51 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.93986142 |
52 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.91020743 |
53 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 0.90849090 |
54 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.89539671 |
55 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.87154508 |
56 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.86690087 |
57 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.86641384 |
58 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.84675668 |
59 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.84417655 |
60 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.80918991 |
61 | RNA transport_Homo sapiens_hsa03013 | 0.80644215 |
62 | Homologous recombination_Homo sapiens_hsa03440 | 0.79940164 |
63 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.79932838 |
64 | Amphetamine addiction_Homo sapiens_hsa05031 | 0.78969630 |
65 | Mismatch repair_Homo sapiens_hsa03430 | 0.77928859 |
66 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.77503789 |
67 | Carbon metabolism_Homo sapiens_hsa01200 | 0.76231838 |
68 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.75857995 |
69 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.75311110 |
70 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.75188958 |
71 | Phototransduction_Homo sapiens_hsa04744 | 0.73514577 |
72 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 0.73341729 |
73 | Lysosome_Homo sapiens_hsa04142 | 0.72858681 |
74 | Alzheimers disease_Homo sapiens_hsa05010 | 0.72553699 |
75 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.72104341 |
76 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.71509086 |
77 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.69367619 |
78 | Taste transduction_Homo sapiens_hsa04742 | 0.68947076 |
79 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.68120043 |
80 | GABAergic synapse_Homo sapiens_hsa04727 | 0.67857933 |
81 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.66311237 |
82 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.66123842 |
83 | Huntingtons disease_Homo sapiens_hsa05016 | 0.65894003 |
84 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.65333629 |
85 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.63691482 |
86 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.61864575 |
87 | Mineral absorption_Homo sapiens_hsa04978 | 0.61442655 |
88 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.60850972 |
89 | Retinol metabolism_Homo sapiens_hsa00830 | 0.60166978 |
90 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.59578579 |
91 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.58457173 |
92 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.58389473 |
93 | Metabolic pathways_Homo sapiens_hsa01100 | 0.56922887 |
94 | Circadian rhythm_Homo sapiens_hsa04710 | 0.56760337 |
95 | Parkinsons disease_Homo sapiens_hsa05012 | 0.54479820 |
96 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.54244139 |
97 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.53347746 |
98 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.52104278 |
99 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.51888878 |
100 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.51580645 |
101 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.51499435 |
102 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.49134789 |
103 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.48660511 |
104 | Renin secretion_Homo sapiens_hsa04924 | 0.48303885 |
105 | Morphine addiction_Homo sapiens_hsa05032 | 0.46406169 |
106 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.45779554 |
107 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.45655010 |
108 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.42734216 |
109 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.41414907 |
110 | Protein digestion and absorption_Homo sapiens_hsa04974 | 0.40540409 |
111 | Glutamatergic synapse_Homo sapiens_hsa04724 | 0.39617475 |
112 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.39606277 |
113 | Circadian entrainment_Homo sapiens_hsa04713 | 0.39007735 |
114 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.38808036 |
115 | Purine metabolism_Homo sapiens_hsa00230 | 0.38663800 |
116 | Lysine degradation_Homo sapiens_hsa00310 | 0.36845090 |
117 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.36660250 |
118 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.35193896 |
119 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.34877284 |
120 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.34863015 |
121 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.34162775 |
122 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.33916257 |
123 | Prion diseases_Homo sapiens_hsa05020 | 0.33323670 |
124 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 0.32655763 |
125 | PPAR signaling pathway_Homo sapiens_hsa03320 | 0.32122629 |
126 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.31645971 |
127 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.30774804 |
128 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.29517320 |
129 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.28711230 |
130 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.26441087 |