UFL1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1signal peptide processing (GO:0006465)5.90045111
2ER overload response (GO:0006983)5.60168691
3Golgi transport vesicle coating (GO:0048200)5.52130518
4COPI coating of Golgi vesicle (GO:0048205)5.52130518
5regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway (GO:19022354.93966789
6erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)4.88733904
7L-phenylalanine catabolic process (GO:0006559)4.88733904
8COPII vesicle coating (GO:0048208)4.63143793
9fatty acid elongation (GO:0030497)4.52780542
10nucleotide transmembrane transport (GO:1901679)4.39049391
11cellular ketone body metabolic process (GO:0046950)4.38686904
12central nervous system myelination (GO:0022010)4.36473428
13axon ensheathment in central nervous system (GO:0032291)4.36473428
14erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)4.11881438
15L-phenylalanine metabolic process (GO:0006558)4.11881438
16intraciliary transport (GO:0042073)3.99746289
17regulation of acetyl-CoA biosynthetic process from pyruvate (GO:0010510)3.89053447
18exocrine pancreas development (GO:0031017)3.86398407
19ketone body metabolic process (GO:1902224)3.78426162
20endocrine pancreas development (GO:0031018)3.78156294
21ER-associated ubiquitin-dependent protein catabolic process (GO:0030433)3.63927289
22regulation of acyl-CoA biosynthetic process (GO:0050812)3.58573896
23eye photoreceptor cell differentiation (GO:0001754)3.57515566
24photoreceptor cell differentiation (GO:0046530)3.57515566
25regulation of hexokinase activity (GO:1903299)3.57127213
26regulation of glucokinase activity (GO:0033131)3.57127213
27maintenance of protein localization in endoplasmic reticulum (GO:0035437)3.47222675
28protein targeting to Golgi (GO:0000042)3.45944186
29retrograde vesicle-mediated transport, Golgi to ER (GO:0006890)3.43858962
30somite rostral/caudal axis specification (GO:0032525)3.42790108
31peptide hormone processing (GO:0016486)3.40844311
32aromatic amino acid family catabolic process (GO:0009074)3.36040374
33intra-Golgi vesicle-mediated transport (GO:0006891)3.35831722
34protein maturation by protein folding (GO:0022417)3.33818514
35protein localization to Golgi apparatus (GO:0034067)3.27905671
36prenylation (GO:0097354)3.27391015
37protein prenylation (GO:0018342)3.27391015
38positive regulation of protein autophosphorylation (GO:0031954)3.27124836
39negative regulation of neurotransmitter secretion (GO:0046929)3.22112800
40magnesium ion transport (GO:0015693)3.20322920
41mitotic sister chromatid cohesion (GO:0007064)3.20203304
42glandular epithelial cell differentiation (GO:0002067)3.17086445
43nonmotile primary cilium assembly (GO:0035058)3.16889286
44positive regulation of histone H3-K4 methylation (GO:0051571)3.15077178
45response to redox state (GO:0051775)3.12581249
46regulation of sulfur metabolic process (GO:0042762)3.11941808
47sequestering of metal ion (GO:0051238)3.11239351
48nucleotide transport (GO:0006862)3.10749458
49nucleoside diphosphate catabolic process (GO:0009134)3.10215760
50response to nitrosative stress (GO:0051409)3.05835220
51positive regulation of cellular amine metabolic process (GO:0033240)3.01070227
52pyrimidine-containing compound transmembrane transport (GO:0072531)2.95781320
53regulation of coenzyme metabolic process (GO:0051196)2.95154029
54regulation of cofactor metabolic process (GO:0051193)2.95154029
55retrograde transport, vesicle recycling within Golgi (GO:0000301)2.94830068
56genitalia morphogenesis (GO:0035112)2.92166913
57monoubiquitinated protein deubiquitination (GO:0035520)2.91987450
58negative regulation of neurotransmitter transport (GO:0051589)2.91923580
59epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)2.89970409
60establishment of protein localization to Golgi (GO:0072600)2.88033224
61cilium morphogenesis (GO:0060271)2.86906497
62intestinal cholesterol absorption (GO:0030299)2.85151878
63cholesterol biosynthetic process (GO:0006695)2.85037201
64ER to Golgi vesicle-mediated transport (GO:0006888)2.80316556
65glycerophospholipid catabolic process (GO:0046475)2.80260922
66keratinocyte development (GO:0003334)2.80235840
67protein K11-linked deubiquitination (GO:0035871)2.79711626
68prostate gland growth (GO:0060736)2.79540303
69auditory receptor cell differentiation (GO:0042491)2.78809937
70mannosylation (GO:0097502)2.78758851
71pharyngeal system development (GO:0060037)2.76570721
72neural tube formation (GO:0001841)2.76489288
73preassembly of GPI anchor in ER membrane (GO:0016254)2.76305651
74response to pheromone (GO:0019236)2.75315405
75regulation of meiosis I (GO:0060631)2.73576298
76lipid particle organization (GO:0034389)2.71924076
77vesicle coating (GO:0006901)2.70993436
78mRNA modification (GO:0016556)2.70607050
79peptidyl-cysteine modification (GO:0018198)2.70422297
80creatine metabolic process (GO:0006600)2.69466326
81detection of calcium ion (GO:0005513)2.69277421
82regulation of centriole replication (GO:0046599)2.67877972
83protein N-linked glycosylation via asparagine (GO:0018279)2.67561690
84centriole replication (GO:0007099)2.66392279
85intestinal epithelial cell development (GO:0060576)2.66308178
86non-recombinational repair (GO:0000726)2.65499819
87double-strand break repair via nonhomologous end joining (GO:0006303)2.65499819
88positive regulation of mitotic metaphase/anaphase transition (GO:0045842)2.65310863
89positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)2.65310863
90positive regulation of mitotic sister chromatid separation (GO:1901970)2.65310863
91GPI anchor metabolic process (GO:0006505)2.64918696
92protein retention in ER lumen (GO:0006621)2.64846346
93tyrosine metabolic process (GO:0006570)2.64675401
94positive regulation of glycolytic process (GO:0045821)2.63897869
95branched-chain amino acid catabolic process (GO:0009083)2.62195097
96dopamine biosynthetic process (GO:0042416)2.61843283
97ribonucleoprotein complex disassembly (GO:0032988)2.60945763
98peptidyl-asparagine modification (GO:0018196)2.60809070
99vascular smooth muscle contraction (GO:0014829)2.60777902
100negative regulation of DNA-dependent DNA replication (GO:2000104)2.60331434
101zinc ion transport (GO:0006829)2.59813841
102nuclear pore complex assembly (GO:0051292)2.58718947
103protein N-linked glycosylation (GO:0006487)2.58094551
104regulation of DNA endoreduplication (GO:0032875)2.57769400
105early endosome to late endosome transport (GO:0045022)2.57278331
106DNA ligation (GO:0006266)2.56838987
107long-chain fatty-acyl-CoA biosynthetic process (GO:0035338)2.56791498
108histone H2A acetylation (GO:0043968)2.56707564
109activation of signaling protein activity involved in unfolded protein response (GO:0006987)2.56518531
110epithelial cilium movement (GO:0003351)2.56358994
111regulation of type B pancreatic cell apoptotic process (GO:2000674)2.55102874
112single strand break repair (GO:0000012)2.54726845
113coenzyme catabolic process (GO:0009109)2.54387426
114GPI anchor biosynthetic process (GO:0006506)2.53742540
115fucose metabolic process (GO:0006004)2.53707264
116DNA double-strand break processing (GO:0000729)2.53210816
117regulation of protein glycosylation (GO:0060049)2.49395546
118negative regulation of JUN kinase activity (GO:0043508)2.49383263
119myelination (GO:0042552)2.49212251
120replication fork processing (GO:0031297)2.47972763
121response to dietary excess (GO:0002021)2.47695869
122water-soluble vitamin biosynthetic process (GO:0042364)2.47186789
123protein localization to cilium (GO:0061512)2.46553247
124tryptophan metabolic process (GO:0006568)2.46073141
125ensheathment of neurons (GO:0007272)2.46004893
126axon ensheathment (GO:0008366)2.46004893
127cellular glucuronidation (GO:0052695)2.45958590
128apical protein localization (GO:0045176)2.45572476
129very long-chain fatty acid metabolic process (GO:0000038)2.45364801
130aromatic amino acid family metabolic process (GO:0009072)2.45300270
131uronic acid metabolic process (GO:0006063)2.44341995
132glucuronate metabolic process (GO:0019585)2.44341995
133fatty-acyl-CoA biosynthetic process (GO:0046949)2.44302849
134positive regulation of growth hormone secretion (GO:0060124)2.43802638
135positive regulation of insulin secretion (GO:0032024)2.43256957
136axoneme assembly (GO:0035082)2.43253290
137nuclear pore organization (GO:0006999)2.42862065
138regulation of beta-amyloid formation (GO:1902003)2.42817754
139lactate metabolic process (GO:0006089)2.42334245
140asymmetric protein localization (GO:0008105)2.41913226
141presynaptic membrane assembly (GO:0097105)2.40190384
142fatty-acyl-CoA metabolic process (GO:0035337)2.39503020
143regulation of Golgi to plasma membrane protein transport (GO:0042996)2.38865076
144sterol biosynthetic process (GO:0016126)2.37294501
145branched-chain amino acid metabolic process (GO:0009081)2.36960922
146purine ribonucleoside bisphosphate metabolic process (GO:0034035)2.35779735
1473-phosphoadenosine 5-phosphosulfate metabolic process (GO:0050427)2.35779735
148type B pancreatic cell development (GO:0003323)2.35703962
149pancreas development (GO:0031016)2.35521112
150oligodendrocyte differentiation (GO:0048709)2.35320159
151microtubule anchoring (GO:0034453)2.35047135
152C-terminal protein lipidation (GO:0006501)2.34830780
153hormone catabolic process (GO:0042447)2.34715055
154regulation of ER to Golgi vesicle-mediated transport (GO:0060628)2.34512878
155positive regulation of nuclease activity (GO:0032075)2.34329447
156negative regulation of digestive system process (GO:0060457)2.33914616
157platelet dense granule organization (GO:0060155)2.33542415
158acrosome assembly (GO:0001675)2.33443882
159mitotic G2 DNA damage checkpoint (GO:0007095)2.33127265
160ether lipid metabolic process (GO:0046485)2.32580243
161regulation of calcineurin-NFAT signaling cascade (GO:0070884)2.32338822
162aldehyde catabolic process (GO:0046185)2.31639242
163telomere maintenance via telomerase (GO:0007004)2.31527636
164Sertoli cell development (GO:0060009)2.30912185
165succinate metabolic process (GO:0006105)2.30639879
166UDP-N-acetylglucosamine metabolic process (GO:0006047)2.30500010
167organelle disassembly (GO:1903008)2.29726396
168indolalkylamine metabolic process (GO:0006586)2.27739645
169intra-S DNA damage checkpoint (GO:0031573)2.26790994
170regulation of catecholamine metabolic process (GO:0042069)2.26694903
171regulation of dopamine metabolic process (GO:0042053)2.26694903
172xenobiotic catabolic process (GO:0042178)2.26355632
173pteridine-containing compound biosynthetic process (GO:0042559)2.25095617
174long-chain fatty-acyl-CoA metabolic process (GO:0035336)2.24993262
175thioester biosynthetic process (GO:0035384)2.24565622
176regulation of acrosome reaction (GO:0060046)2.24432158

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1SALL1_21062744_ChIP-ChIP_HESCs_Human3.25500614
2FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse3.09307559
3GBX2_23144817_ChIP-Seq_PC3_Human2.95490191
4TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.70108029
5TAF15_26573619_Chip-Seq_HEK293_Human2.62212768
6POU3F2_20337985_ChIP-ChIP_501MEL_Human2.59918942
7E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.26834314
8ZFP57_27257070_Chip-Seq_ESCs_Mouse2.20527120
9KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.19206958
10ELK1_19687146_ChIP-ChIP_HELA_Human2.18248431
11PIAS1_25552417_ChIP-Seq_VCAP_Human2.15149340
12SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse2.08505396
13PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse2.06312995
14VDR_22108803_ChIP-Seq_LS180_Human2.01866524
15CEBPD_23245923_ChIP-Seq_MEFs_Mouse2.00358407
16GABP_17652178_ChIP-ChIP_JURKAT_Human1.93875593
17PADI4_21655091_ChIP-ChIP_MCF-7_Human1.91514624
18OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.90547126
19ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.83669823
20ZNF274_21170338_ChIP-Seq_K562_Hela1.77573398
21GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.74951854
22PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.73862870
23CTBP2_25329375_ChIP-Seq_LNCAP_Human1.72256421
24AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.72061264
25FUS_26573619_Chip-Seq_HEK293_Human1.69703667
26P300_19829295_ChIP-Seq_ESCs_Human1.68149406
27EST1_17652178_ChIP-ChIP_JURKAT_Human1.67068585
28GATA1_22025678_ChIP-Seq_K562_Human1.64298671
29KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.60913771
30EGR1_23403033_ChIP-Seq_LIVER_Mouse1.59096851
31CTBP1_25329375_ChIP-Seq_LNCAP_Human1.58130815
32SMAD_19615063_ChIP-ChIP_OVARY_Human1.57826979
33ER_23166858_ChIP-Seq_MCF-7_Human1.56286180
34GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.55927161
35PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.55347777
36IGF1R_20145208_ChIP-Seq_DFB_Human1.54823726
37MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.51471495
38CDX2_19796622_ChIP-Seq_MESCs_Mouse1.51254872
39LXR_22158963_ChIP-Seq_LIVER_Mouse1.50966050
40NANOG_18555785_Chip-Seq_ESCs_Mouse1.48861960
41DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.46437798
42SMAD4_21799915_ChIP-Seq_A2780_Human1.46365559
43BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.46146046
44PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.45060234
45SMAD3_21741376_ChIP-Seq_EPCs_Human1.44550389
46EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.44251721
47RBPJ_22232070_ChIP-Seq_NCS_Mouse1.44214797
48ZNF217_24962896_ChIP-Seq_MCF-7_Human1.43894034
49RXR_22158963_ChIP-Seq_LIVER_Mouse1.43467339
50HTT_18923047_ChIP-ChIP_STHdh_Human1.41409226
51IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.40400404
52CBP_20019798_ChIP-Seq_JUKART_Human1.40400404
53HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.40233684
54RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.39249707
55VDR_23849224_ChIP-Seq_CD4+_Human1.39027099
56TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.38890720
57SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.38866567
58PCGF2_27294783_Chip-Seq_ESCs_Mouse1.38129297
59EZH2_27294783_Chip-Seq_NPCs_Mouse1.37751091
60FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human1.35734930
61TOP2B_26459242_ChIP-Seq_MCF-7_Human1.34148539
62FLI1_27457419_Chip-Seq_LIVER_Mouse1.34122401
63CDX2_22108803_ChIP-Seq_LS180_Human1.33682403
64FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.33332735
65P53_22387025_ChIP-Seq_ESCs_Mouse1.32759625
66FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.32721584
67BMI1_23680149_ChIP-Seq_NPCS_Mouse1.31683035
68NRF2_20460467_ChIP-Seq_MEFs_Mouse1.30914609
69NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.30914609
70FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.30773028
71SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.30063568
72STAT3_23295773_ChIP-Seq_U87_Human1.29340384
73PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.28816070
74SUZ12_27294783_Chip-Seq_NPCs_Mouse1.27137864
75TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.26524699
76NR3C1_21868756_ChIP-Seq_MCF10A_Human1.25974586
77SUZ12_18555785_Chip-Seq_ESCs_Mouse1.23771723
78CRX_20693478_ChIP-Seq_RETINA_Mouse1.23376814
79HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.22639887
80CMYC_18555785_Chip-Seq_ESCs_Mouse1.21778767
81BCAT_22108803_ChIP-Seq_LS180_Human1.21635593
82AR_21572438_ChIP-Seq_LNCaP_Human1.21553371
83* SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.21551982
84TCF4_22108803_ChIP-Seq_LS180_Human1.21140674
85STAT3_18555785_Chip-Seq_ESCs_Mouse1.20538207
86SALL4_22934838_ChIP-ChIP_CD34+_Human1.19888515
87SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.19637529
88TAL1_26923725_Chip-Seq_HPCs_Mouse1.19389930
89UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.19215268
90P300_18555785_Chip-Seq_ESCs_Mouse1.18847787
91TCF4_23295773_ChIP-Seq_U87_Human1.17872918
92NR3C1_23031785_ChIP-Seq_PC12_Mouse1.17712665
93AR_25329375_ChIP-Seq_VCAP_Human1.17215118
94IRF1_19129219_ChIP-ChIP_H3396_Human1.16460711
95WT1_19549856_ChIP-ChIP_CCG9911_Human1.16380950
96EWS_26573619_Chip-Seq_HEK293_Human1.15399178
97CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.14756731
98AR_21915096_ChIP-Seq_LNCaP-1F5_Human1.14568259
99SOX2_19829295_ChIP-Seq_ESCs_Human1.14530822
100NANOG_19829295_ChIP-Seq_ESCs_Human1.14530822
101SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.13347315
102E2F4_17652178_ChIP-ChIP_JURKAT_Human1.13270173
103ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.12817683
104E2F1_18555785_Chip-Seq_ESCs_Mouse1.12267455
105FOXA1_25552417_ChIP-Seq_VCAP_Human1.12021026
106NFE2_27457419_Chip-Seq_LIVER_Mouse1.11055604
107SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.10416559
108NMYC_18555785_Chip-Seq_ESCs_Mouse1.10236863
109CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.10144683
110ARNT_22903824_ChIP-Seq_MCF-7_Human1.09627495
111FOXA1_21572438_ChIP-Seq_LNCaP_Human1.09526818
112CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.09469764
113RUNX1_27457419_Chip-Seq_LIVER_Mouse1.09187083
114CBX2_27304074_Chip-Seq_ESCs_Mouse1.09166331
115EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.07349451
116SOX2_18555785_Chip-Seq_ESCs_Mouse1.07025307
117EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.06788724
118OCT4_21477851_ChIP-Seq_ESCs_Mouse1.06780193
119TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.06716258
120FOXM1_26456572_ChIP-Seq_MCF-7_Human1.06311561
121MTF2_20144788_ChIP-Seq_MESCs_Mouse1.05902615
122FOXA1_26743006_Chip-Seq_LNCaP-abl_Human1.05785572
123SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.05595406
124CREB1_15753290_ChIP-ChIP_HEK293T_Human1.05581494
125SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.05435553
126RUNX2_22187159_ChIP-Seq_PCA_Human1.05337151
127LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.05199718
128KLF5_20875108_ChIP-Seq_MESCs_Mouse1.04937636
129EZH2_27304074_Chip-Seq_ESCs_Mouse1.04455822
130HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.04310887
131MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.03811764
132PCGF2_27294783_Chip-Seq_NPCs_Mouse1.03739411
133KDM2B_26808549_Chip-Seq_REH_Human1.03203122
134FLI1_21867929_ChIP-Seq_TH2_Mouse1.01324303
135OCT4_18555785_Chip-Seq_ESCs_Mouse1.01233485

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008057_abnormal_DNA_replication4.16609646
2MP0002139_abnormal_hepatobiliary_system3.51666253
3MP0004043_abnormal_pH_regulation3.27762719
4MP0003183_abnormal_peptide_metabolism3.16176357
5MP0003195_calcinosis3.11789815
6MP0005365_abnormal_bile_salt2.98863150
7MP0005646_abnormal_pituitary_gland2.97945758
8MP0005379_endocrine/exocrine_gland_phen2.83527060
9MP0003787_abnormal_imprinting2.83339010
10MP0009780_abnormal_chondrocyte_physiolo2.79601958
11MP0008877_abnormal_DNA_methylation2.79287132
12MP0010386_abnormal_urinary_bladder2.55388460
13MP0003890_abnormal_embryonic-extraembry2.46671051
14MP0002837_dystrophic_cardiac_calcinosis2.40867715
15MP0003122_maternal_imprinting2.40467424
16MP0005645_abnormal_hypothalamus_physiol2.38609936
17MP0005220_abnormal_exocrine_pancreas2.35076283
18MP0010234_abnormal_vibrissa_follicle2.28381528
19MP0000013_abnormal_adipose_tissue2.25684326
20MP0008058_abnormal_DNA_repair2.25003835
21MP0001666_abnormal_nutrient_absorption2.21579165
22MP0002693_abnormal_pancreas_physiology2.19932102
23MP0005085_abnormal_gallbladder_physiolo2.18100198
24MP0000920_abnormal_myelination2.12693831
25MP0000427_abnormal_hair_cycle2.11755645
26MP0003868_abnormal_feces_composition2.11515989
27MP0008875_abnormal_xenobiotic_pharmacok2.10989025
28MP0000569_abnormal_digit_pigmentation2.10557797
29MP0006054_spinal_hemorrhage2.07363528
30MP0001944_abnormal_pancreas_morphology2.07145762
31MP0006072_abnormal_retinal_apoptosis1.91251366
32MP0003121_genomic_imprinting1.89263108
33MP0000566_synostosis1.84478150
34MP0004264_abnormal_extraembryonic_tissu1.74709730
35MP0003941_abnormal_skin_development1.74358316
36MP0003806_abnormal_nucleotide_metabolis1.74017981
37MP0005367_renal/urinary_system_phenotyp1.73277627
38MP0000516_abnormal_urinary_system1.73277627
39MP0010678_abnormal_skin_adnexa1.72839229
40MP0005551_abnormal_eye_electrophysiolog1.66600354
41MP0003880_abnormal_central_pattern1.64659901
42MP0002876_abnormal_thyroid_physiology1.62518911
43MP0005408_hypopigmentation1.61554882
44MP0005360_urolithiasis1.57151902
45MP0004147_increased_porphyrin_level1.54538366
46MP0003718_maternal_effect1.54359886
47MP0002009_preneoplasia1.53967177
48MP0000613_abnormal_salivary_gland1.53888844
49MP0010352_gastrointestinal_tract_polyps1.50967908
50MP0004215_abnormal_myocardial_fiber1.50303550
51MP0000462_abnormal_digestive_system1.48568701
52MP0009697_abnormal_copulation1.47750102
53MP0003252_abnormal_bile_duct1.43754197
54MP0000383_abnormal_hair_follicle1.41553805
55MP0002078_abnormal_glucose_homeostasis1.39863386
56MP0003690_abnormal_glial_cell1.39562731
57MP0004084_abnormal_cardiac_muscle1.35622323
58MP0005310_abnormal_salivary_gland1.35442647
59MP0005647_abnormal_sex_gland1.34390671
60MP0005248_abnormal_Harderian_gland1.34370129
61MP0001905_abnormal_dopamine_level1.32060643
62MP0005332_abnormal_amino_acid1.31894525
63MP0000631_abnormal_neuroendocrine_gland1.31411567
64MP0001765_abnormal_ion_homeostasis1.31009404
65MP0005171_absent_coat_pigmentation1.28248104
66MP0000003_abnormal_adipose_tissue1.26897120
67MP0002163_abnormal_gland_morphology1.25255071
68MP0005084_abnormal_gallbladder_morpholo1.23682897
69MP0005083_abnormal_biliary_tract1.21882912
70MP0002166_altered_tumor_susceptibility1.21879065
71MP0002118_abnormal_lipid_homeostasis1.21410428
72MP0001346_abnormal_lacrimal_gland1.21332329
73MP0005253_abnormal_eye_physiology1.20629507
74MP0008775_abnormal_heart_ventricle1.18981066
75MP0004145_abnormal_muscle_electrophysio1.17408575
76MP0002272_abnormal_nervous_system1.17163846
77MP0003959_abnormal_lean_body1.16532892
78MP0002229_neurodegeneration1.16055674
79MP0010094_abnormal_chromosome_stability1.15991924
80MP0005409_darkened_coat_color1.15919166
81MP0004885_abnormal_endolymph1.15046073
82MP0001502_abnormal_circadian_rhythm1.14408330
83MP0004270_analgesia1.13126856
84MP0000230_abnormal_systemic_arterial1.12498195
85MP0003283_abnormal_digestive_organ1.12362274
86MP0003786_premature_aging1.12088396
87MP0004742_abnormal_vestibular_system1.11274293
88MP0009643_abnormal_urine_homeostasis1.11107169
89MP0002877_abnormal_melanocyte_morpholog1.10209755
90MP0002909_abnormal_adrenal_gland1.09966556
91MP0000639_abnormal_adrenal_gland1.09250904
92MP0001486_abnormal_startle_reflex1.08452298
93MP0005058_abnormal_lysosome_morphology1.08129085
94MP0005187_abnormal_penis_morphology1.06533488
95MP0002234_abnormal_pharynx_morphology1.03042694
96MP0005636_abnormal_mineral_homeostasis1.02386187
97MP0006036_abnormal_mitochondrial_physio1.02149975
98MP0001764_abnormal_homeostasis1.00753337
99MP0001529_abnormal_vocalization0.98981925
100MP0000647_abnormal_sebaceous_gland0.98674000
101MP0001984_abnormal_olfaction0.97613457
102MP0003634_abnormal_glial_cell0.96258104
103MP0001661_extended_life_span0.94486836
104MP0008789_abnormal_olfactory_epithelium0.94337083
105MP0000372_irregular_coat_pigmentation0.94225469
106MP0005535_abnormal_body_temperature0.93508207
107MP0003186_abnormal_redox_activity0.92390593
108MP0008995_early_reproductive_senescence0.92070264
109MP0004134_abnormal_chest_morphology0.90618326
110MP0004484_altered_response_of0.89182884
111MP0001485_abnormal_pinna_reflex0.86913771
112MP0003953_abnormal_hormone_level0.86870575
113MP0002295_abnormal_pulmonary_circulatio0.85797804
114MP0004142_abnormal_muscle_tone0.85544597
115MP0010329_abnormal_lipoprotein_level0.84940543
116MP0000678_abnormal_parathyroid_gland0.84275100
117MP0008007_abnormal_cellular_replicative0.84263754
118MP0001664_abnormal_digestion0.83605380
119MP0002928_abnormal_bile_duct0.82971482
120MP0005395_other_phenotype0.82797073
121MP0002396_abnormal_hematopoietic_system0.81678238
122MP0001986_abnormal_taste_sensitivity0.81354770
123MP0002938_white_spotting0.80796440
124MP0009703_decreased_birth_body0.80417999
125MP0002006_tumorigenesis0.80258190
126MP0002269_muscular_atrophy0.79707381
127MP0003011_delayed_dark_adaptation0.79700086
128MP0009115_abnormal_fat_cell0.79138642
129MP0002638_abnormal_pupillary_reflex0.78655845
130MP0004019_abnormal_vitamin_homeostasis0.78557401
131MP0002971_abnormal_brown_adipose0.78146057
132MP0003937_abnormal_limbs/digits/tail_de0.77100471
133MP0003567_abnormal_fetal_cardiomyocyte0.76959876
134MP0001756_abnormal_urination0.75616897
135MP0003943_abnormal_hepatobiliary_system0.75560133
136MP0010307_abnormal_tumor_latency0.74387965
137MP0003656_abnormal_erythrocyte_physiolo0.73745074
138MP0003172_abnormal_lysosome_physiology0.72983747
139MP0004036_abnormal_muscle_relaxation0.72973476
140MP0005410_abnormal_fertilization0.72715573
141MP0003632_abnormal_nervous_system0.72419265
142MP0003950_abnormal_plasma_membrane0.71503117
143MP0005266_abnormal_metabolism0.70658655
144MP0005334_abnormal_fat_pad0.68835690
145MP0005394_taste/olfaction_phenotype0.68827290
146MP0004085_abnormal_heartbeat0.68669618
147MP0005195_abnormal_posterior_eye0.67911462
148MP0000538_abnormal_urinary_bladder0.67298919
149MP0002572_abnormal_emotion/affect_behav0.66890929
150MP0003329_amyloid_beta_deposits0.66833566
151MP0001324_abnormal_eye_pigmentation0.66612598
152MP0002090_abnormal_vision0.65286756

Predicted human phenotypes

RankGene SetZ-score
1Hypoglycemic seizures (HP:0002173)4.85381110
2Hyperinsulinemic hypoglycemia (HP:0000825)4.81338961
3Symptomatic seizures (HP:0011145)4.44294893
4Hypoglycemic coma (HP:0001325)4.43185562
5Abnormality of aromatic amino acid family metabolism (HP:0004338)4.30106081
6Papillary thyroid carcinoma (HP:0002895)4.05180958
7Conjugated hyperbilirubinemia (HP:0002908)3.41951382
8Pancreatic islet-cell hyperplasia (HP:0004510)3.41282914
9Abnormality of the intrinsic pathway (HP:0010989)3.36606065
10Ketoacidosis (HP:0001993)3.19648932
11Intrahepatic cholestasis (HP:0001406)3.18986739
12Elevated circulating parathyroid hormone (PTH) level (HP:0003165)3.15980168
13Volvulus (HP:0002580)3.10159697
14Generalized aminoaciduria (HP:0002909)3.08337083
15Abnormality of the pancreatic islet cells (HP:0006476)3.08309508
16Abnormality of endocrine pancreas physiology (HP:0012093)3.08309508
17Abnormality of vitamin B metabolism (HP:0004340)2.98700886
18Thyroid carcinoma (HP:0002890)2.97977587
19Hypothermia (HP:0002045)2.97796009
20Prolonged partial thromboplastin time (HP:0003645)2.97365442
21Abnormality of methionine metabolism (HP:0010901)2.90472949
22Ketosis (HP:0001946)2.90255161
23Abnormality of the renal cortex (HP:0011035)2.82596605
24Degeneration of the lateral corticospinal tracts (HP:0002314)2.79779110
25Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)2.79779110
26Congenital sensorineural hearing impairment (HP:0008527)2.79253696
27Hyperglycemia (HP:0003074)2.77530387
28Neurofibrillary tangles (HP:0002185)2.75688220
29Decreased circulating renin level (HP:0003351)2.72169140
30Increased serum pyruvate (HP:0003542)2.69778248
31Abnormality of aspartate family amino acid metabolism (HP:0010899)2.67884796
32Fat malabsorption (HP:0002630)2.62342263
33Exercise-induced muscle cramps (HP:0003710)2.61290269
34Tubulointerstitial nephritis (HP:0001970)2.58168114
35Calf muscle hypertrophy (HP:0008981)2.53448697
36Abnormal biliary tract morphology (HP:0012440)2.53150273
37Proximal tubulopathy (HP:0000114)2.47082306
38Abnormality of glycolysis (HP:0004366)2.46715492
39Abnormal pancreas size (HP:0012094)2.44246589
40Abnormal protein glycosylation (HP:0012346)2.43964546
41Abnormal glycosylation (HP:0012345)2.43964546
42Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.43964546
43Abnormal protein N-linked glycosylation (HP:0012347)2.43964546
44Abnormality of the common coagulation pathway (HP:0010990)2.43343062
45Abnormality of vitamin metabolism (HP:0100508)2.42952408
46Abnormality of the vitamin B12 metabolism (HP:0004341)2.35748386
47Anteriorly placed anus (HP:0001545)2.34777217
48Insulin-resistant diabetes mellitus (HP:0000831)2.34385765
49Medial flaring of the eyebrow (HP:0010747)2.33929811
50Parakeratosis (HP:0001036)2.33382438
51Abnormality of calcium-phosphate metabolism (HP:0100530)2.30436625
52Hyperkalemia (HP:0002153)2.30216997
53Biliary tract neoplasm (HP:0100574)2.29788773
54Hyperglycinuria (HP:0003108)2.29417618
55Steatorrhea (HP:0002570)2.29257746
56Muscle hypertrophy of the lower extremities (HP:0008968)2.25158253
57Colon cancer (HP:0003003)2.24746489
58Alacrima (HP:0000522)2.24656018
59Neuroendocrine neoplasm (HP:0100634)2.24198189
60Hypomagnesemia (HP:0002917)2.22894489
61Type I transferrin isoform profile (HP:0003642)2.22480173
62Retinal dysplasia (HP:0007973)2.21650578
63Retinal atrophy (HP:0001105)2.20432843
64Neoplasm of the adrenal gland (HP:0100631)2.19904240
65Vacuolated lymphocytes (HP:0001922)2.18100098
66Large for gestational age (HP:0001520)2.18060771
67Hyperglycinemia (HP:0002154)2.17610710
68Acute encephalopathy (HP:0006846)2.16925088
69Congenital primary aphakia (HP:0007707)2.11509307
70Overlapping toe (HP:0001845)2.11196352
71Hypokalemia (HP:0002900)2.10882032
72Acute necrotizing encephalopathy (HP:0006965)2.10729446
73Pheochromocytoma (HP:0002666)2.09959507
74EEG with generalized epileptiform discharges (HP:0011198)2.09718821
75Epidermoid cyst (HP:0200040)2.09420990
76Dysostosis multiplex (HP:0000943)2.08619395
77Enlarged kidneys (HP:0000105)2.08617603
78Hyperlipoproteinemia (HP:0010980)2.07754429
79Barrel-shaped chest (HP:0001552)2.07291313
80Methylmalonic aciduria (HP:0012120)2.06970229
81Hepatoblastoma (HP:0002884)2.06363555
82Epileptiform EEG discharges (HP:0011182)2.05694415
83Vaginal atresia (HP:0000148)2.05623750
84Decreased lacrimation (HP:0000633)2.05542124
85Hypoplasia of the uterus (HP:0000013)2.03960173
86Renal cortical cysts (HP:0000803)2.02784981
87Gait imbalance (HP:0002141)2.02304484
88Abnormality of glycine metabolism (HP:0010895)2.01772079
89Abnormality of serine family amino acid metabolism (HP:0010894)2.01772079
90Neoplasm of the small intestine (HP:0100833)2.01651531
91Abnormality of urine glucose concentration (HP:0011016)2.01422924
92Glycosuria (HP:0003076)2.01422924
93Progressive neurologic deterioration (HP:0002344)2.00253583
94Methylmalonic acidemia (HP:0002912)1.98646120
95Hypsarrhythmia (HP:0002521)1.97795708
96Genital tract atresia (HP:0001827)1.97429065
973-Methylglutaconic aciduria (HP:0003535)1.97233902
98Increased CSF lactate (HP:0002490)1.96220663
99Hypoplastic labia majora (HP:0000059)1.95683683
100Abnormality of potassium homeostasis (HP:0011042)1.95386665
101Acanthocytosis (HP:0001927)1.95254792
102Nephrogenic diabetes insipidus (HP:0009806)1.94952129
103Hypobetalipoproteinemia (HP:0003563)1.94504033
104Poor coordination (HP:0002370)1.93183073
105Morphological abnormality of the inner ear (HP:0011390)1.91309674
106Abnormality of the renal medulla (HP:0100957)1.90691761
107Abnormality of chromosome stability (HP:0003220)1.90431250
108Abnormality of chloride homeostasis (HP:0011422)1.89750730
109Right ventricular cardiomyopathy (HP:0011663)1.88261866
110Ovarian neoplasm (HP:0100615)1.88081010
111Oligodactyly (hands) (HP:0001180)1.87012109
112Rhabdomyosarcoma (HP:0002859)1.86194881
113Abnormal mitochondria in muscle tissue (HP:0008316)1.85101173
114Abnormality of renin-angiotensin system (HP:0000847)1.84842695
115Hepatic necrosis (HP:0002605)1.83953081
116Abnormality of cochlea (HP:0000375)1.83827521
117Pancreatic fibrosis (HP:0100732)1.83750328
118Cerebral edema (HP:0002181)1.82177749
119Progressive macrocephaly (HP:0004481)1.82054489
120Chronic hepatic failure (HP:0100626)1.81586608
121Gaze-evoked nystagmus (HP:0000640)1.80944879
122Nephronophthisis (HP:0000090)1.80710499
123Fair hair (HP:0002286)1.79774517
124Reduced antithrombin III activity (HP:0001976)1.79281214
125Intestinal atresia (HP:0011100)1.79247100
126Cerebral inclusion bodies (HP:0100314)1.78906919
127Bifid tongue (HP:0010297)1.78821322
128Protuberant abdomen (HP:0001538)1.78181697
129Pancreatic cysts (HP:0001737)1.78034440
130Labial hypoplasia (HP:0000066)1.75719855
131Abnormal hair whorl (HP:0010721)1.74470974
132White forelock (HP:0002211)1.74418304
133Abnormality of the labia minora (HP:0012880)1.74290344
134Mitochondrial inheritance (HP:0001427)1.73559369
135Patchy hypopigmentation of hair (HP:0011365)1.73228459
136Osteomalacia (HP:0002749)1.73227543
137Abnormality of the labia majora (HP:0012881)1.73127436
138Xanthomatosis (HP:0000991)1.73016994
139Limb hypertonia (HP:0002509)1.72722624
140Abnormality of long-chain fatty-acid metabolism (HP:0010964)1.72287878
141Disproportionate short-trunk short stature (HP:0003521)1.72266091
142Growth hormone deficiency (HP:0000824)1.72248981
143Abnormal foot bone ossification (HP:0010675)1.71791380
144Metabolic acidosis (HP:0001942)1.71179546
145Exocrine pancreatic insufficiency (HP:0001738)1.70824519
146Blue irides (HP:0000635)1.70252586
147Supernumerary spleens (HP:0009799)1.69889073
148Abnormality of serum amino acid levels (HP:0003112)1.69870374
149Muscular hypotonia of the trunk (HP:0008936)1.69526863
150Abnormality of magnesium homeostasis (HP:0004921)1.68736725
151Mucopolysacchariduria (HP:0008155)1.67623292
152Urinary glycosaminoglycan excretion (HP:0003541)1.67623292
153Hyperventilation (HP:0002883)1.67441943
154Widely patent fontanelles and sutures (HP:0004492)1.67159374
155Septo-optic dysplasia (HP:0100842)1.65536382
156Increased hepatocellular lipid droplets (HP:0006565)1.65086352
157Medulloblastoma (HP:0002885)1.64765872
158Renal Fanconi syndrome (HP:0001994)1.63894159
159Agitation (HP:0000713)1.63649695

Predicted kinase interactions (KEA)

RankGene SetZ-score
1INSRR4.73341421
2STK393.70325689
3MAPK153.66604948
4FRK3.45220838
5TAOK33.16372398
6ERBB32.78073436
7AKT32.70319366
8WNK42.45052930
9CASK2.22790434
10OXSR12.07643509
11TRIM282.01886930
12TNIK1.84566417
13PIK3CG1.79819850
14MKNK21.77910042
15PASK1.76149394
16BCKDK1.73713872
17EIF2AK11.68677227
18MAP4K21.66518202
19BMPR1B1.65463047
20STK38L1.61427312
21NEK61.57030718
22ACVR1B1.54001996
23STK241.51893380
24EPHB11.51260326
25FGFR31.45383634
26IRAK21.43470424
27PLK21.40704855
28GRK71.40472263
29FER1.40359899
30PKN11.38747364
31NUAK11.36480028
32GRK11.35796003
33WNK11.32224300
34MKNK11.30787694
35NEK91.27965429
36MST41.26589173
37IRAK11.25710663
38MAP3K21.25104224
39MAPKAPK51.24352981
40WNK31.18762744
41UHMK11.18521136
42TSSK61.17742564
43BCR1.16594772
44PLK31.16268828
45ERN11.15927012
46STK31.15192251
47EIF2AK31.15150155
48ADRBK21.14724941
49BMPR21.14311219
50PBK1.13259999
51HIPK21.12633598
52TGFBR11.12413623
53PIK3CA1.12228881
54NEK11.11635317
55BRD41.10173735
56MAP3K121.09064975
57TRPM71.07860259
58SCYL21.07522874
59PRKCE1.07390646
60IRAK31.04959921
61CAMK2D1.04370541
62CAMK2B1.03426826
63TTK1.03303613
64MAP3K131.00733145
65LATS11.00681685
66BRSK20.98191388
67PLK40.95077564
68EPHA30.93555210
69FGFR20.93415768
70MET0.93072592
71SGK2230.91469323
72SGK4940.91469323
73PRPF4B0.88617159
74SIK10.81288751
75IRAK40.80458034
76STK160.79752461
77FGFR10.78727334
78NTRK10.77850678
79PRKCQ0.76960407
80MUSK0.73103666
81CSNK1A1L0.72750180
82PRKAA20.71838017
83CAMK1G0.71682432
84CDK30.70385818
85TAF10.69105274
86LMTK20.68637900
87OBSCN0.68222935
88ITK0.67890519
89CAMK2G0.66640914
90ATM0.66581966
91NTRK30.65959539
92CCNB10.65847602
93MAPK130.65240324
94ARAF0.65085524
95ZAK0.64489777
96PHKG20.64476810
97PHKG10.64476810
98MAP3K140.62082251
99ERBB40.61774543
100CAMK2A0.61658534
101CAMKK20.61114746
102PDK20.60332018
103PNCK0.59619533
104PRKG10.59058117
105MAP2K70.57023582
106MYLK0.56706236
107TEC0.56674775
108CSNK1G30.56550701
109WEE10.55597000
110NLK0.55142403
111CSNK1G20.54534728
112YES10.52540414
113CAMK1D0.52370308
114CSNK1G10.51538318
115TIE10.51329542
116MAP3K40.51218753
117CSNK1E0.49377129
118EPHA40.48742078
119ADRBK10.48376885
120DYRK30.47930823
121PAK30.47442561
122SGK20.46899204
123MAPK70.46603104
124PRKD30.45782594
125KSR10.45085330
126PRKD20.43298366
127PRKACB0.43036348
128CSNK1A10.42798356
129FLT30.41849568
130VRK10.41452313
131PRKD10.41417469
132GSK3A0.39724017
133PRKCG0.39704609
134PRKACA0.39388437
135RPS6KB10.38244884
136SRPK10.38222829
137SGK10.37097733
138CSNK2A20.36030637
139PRKCH0.35909063
140IGF1R0.35564874
141CHEK10.35534958
142PINK10.35203416
143MELK0.34992853
144EIF2AK20.34691754
145PRKAA10.34444670
146CDC42BPA0.34340239
147PLK10.33171231
148JAK10.31739355
149SGK30.31601574
150NME10.30124220

Predicted pathways (KEGG)

RankGene SetZ-score
1Protein export_Homo sapiens_hsa030605.66097812
2Maturity onset diabetes of the young_Homo sapiens_hsa049505.03894816
3Sulfur metabolism_Homo sapiens_hsa009203.92994500
4Fatty acid elongation_Homo sapiens_hsa000622.46509129
5Protein processing in endoplasmic reticulum_Homo sapiens_hsa041412.39758497
6Steroid biosynthesis_Homo sapiens_hsa001002.18721386
7Non-homologous end-joining_Homo sapiens_hsa034502.16575599
8Terpenoid backbone biosynthesis_Homo sapiens_hsa009002.12753483
9Valine, leucine and isoleucine degradation_Homo sapiens_hsa002802.12146990
10Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.85016909
11Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.83729584
12Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.82416786
13Propanoate metabolism_Homo sapiens_hsa006401.79824508
14Histidine metabolism_Homo sapiens_hsa003401.78903203
15Basal transcription factors_Homo sapiens_hsa030221.75635074
16Vibrio cholerae infection_Homo sapiens_hsa051101.69237443
17Primary bile acid biosynthesis_Homo sapiens_hsa001201.68873473
18Tryptophan metabolism_Homo sapiens_hsa003801.68388040
19Butanoate metabolism_Homo sapiens_hsa006501.64005357
20Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.63176615
21Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.51571923
22Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.50276773
23Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.46202292
24Peroxisome_Homo sapiens_hsa041461.43237659
25Folate biosynthesis_Homo sapiens_hsa007901.39633587
26Insulin secretion_Homo sapiens_hsa049111.38322336
27Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.37767540
28RNA degradation_Homo sapiens_hsa030181.37546729
29Caffeine metabolism_Homo sapiens_hsa002321.35915146
30ABC transporters_Homo sapiens_hsa020101.29914403
31N-Glycan biosynthesis_Homo sapiens_hsa005101.25929363
32Oxidative phosphorylation_Homo sapiens_hsa001901.25706073
33Other glycan degradation_Homo sapiens_hsa005111.23797683
34Sphingolipid metabolism_Homo sapiens_hsa006001.19218628
35One carbon pool by folate_Homo sapiens_hsa006701.19084619
36SNARE interactions in vesicular transport_Homo sapiens_hsa041301.18230200
37Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.16639618
38Fatty acid degradation_Homo sapiens_hsa000711.11822923
39Fanconi anemia pathway_Homo sapiens_hsa034601.09460409
40Cocaine addiction_Homo sapiens_hsa050301.05424252
41Pancreatic secretion_Homo sapiens_hsa049721.05035024
42Proteasome_Homo sapiens_hsa030501.05031062
43Ether lipid metabolism_Homo sapiens_hsa005651.03507463
44Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.01095863
45Arginine and proline metabolism_Homo sapiens_hsa003301.00857263
46Fatty acid metabolism_Homo sapiens_hsa012121.00667481
47Steroid hormone biosynthesis_Homo sapiens_hsa001400.99595929
48Starch and sucrose metabolism_Homo sapiens_hsa005000.98519712
49Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.96620954
50Tyrosine metabolism_Homo sapiens_hsa003500.96347086
51Glutathione metabolism_Homo sapiens_hsa004800.93986142
52Cysteine and methionine metabolism_Homo sapiens_hsa002700.91020743
53Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.90849090
54Selenocompound metabolism_Homo sapiens_hsa004500.89539671
55Regulation of autophagy_Homo sapiens_hsa041400.87154508
56Nucleotide excision repair_Homo sapiens_hsa034200.86690087
57Phenylalanine metabolism_Homo sapiens_hsa003600.86641384
58Pentose and glucuronate interconversions_Homo sapiens_hsa000400.84675668
59Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.84417655
60Serotonergic synapse_Homo sapiens_hsa047260.80918991
61RNA transport_Homo sapiens_hsa030130.80644215
62Homologous recombination_Homo sapiens_hsa034400.79940164
63Vitamin B6 metabolism_Homo sapiens_hsa007500.79932838
64Amphetamine addiction_Homo sapiens_hsa050310.78969630
65Mismatch repair_Homo sapiens_hsa034300.77928859
66Chemical carcinogenesis_Homo sapiens_hsa052040.77503789
67Carbon metabolism_Homo sapiens_hsa012000.76231838
68Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.75857995
69beta-Alanine metabolism_Homo sapiens_hsa004100.75311110
70Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.75188958
71Phototransduction_Homo sapiens_hsa047440.73514577
72Complement and coagulation cascades_Homo sapiens_hsa046100.73341729
73Lysosome_Homo sapiens_hsa041420.72858681
74Alzheimers disease_Homo sapiens_hsa050100.72553699
75Pyruvate metabolism_Homo sapiens_hsa006200.72104341
76Collecting duct acid secretion_Homo sapiens_hsa049660.71509086
77Thyroid hormone synthesis_Homo sapiens_hsa049180.69367619
78Taste transduction_Homo sapiens_hsa047420.68947076
79Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.68120043
80GABAergic synapse_Homo sapiens_hsa047270.67857933
81Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.66311237
82Linoleic acid metabolism_Homo sapiens_hsa005910.66123842
83Huntingtons disease_Homo sapiens_hsa050160.65894003
84Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.65333629
85Fat digestion and absorption_Homo sapiens_hsa049750.63691482
86Arginine biosynthesis_Homo sapiens_hsa002200.61864575
87Mineral absorption_Homo sapiens_hsa049780.61442655
88Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.60850972
89Retinol metabolism_Homo sapiens_hsa008300.60166978
90Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.59578579
91alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.58457173
922-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.58389473
93Metabolic pathways_Homo sapiens_hsa011000.56922887
94Circadian rhythm_Homo sapiens_hsa047100.56760337
95Parkinsons disease_Homo sapiens_hsa050120.54479820
96Nitrogen metabolism_Homo sapiens_hsa009100.54244139
97Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.53347746
98Type II diabetes mellitus_Homo sapiens_hsa049300.52104278
99Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.51888878
100TGF-beta signaling pathway_Homo sapiens_hsa043500.51580645
101Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.51499435
102Vitamin digestion and absorption_Homo sapiens_hsa049770.49134789
103Oocyte meiosis_Homo sapiens_hsa041140.48660511
104Renin secretion_Homo sapiens_hsa049240.48303885
105Morphine addiction_Homo sapiens_hsa050320.46406169
106Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.45779554
107p53 signaling pathway_Homo sapiens_hsa041150.45655010
108Carbohydrate digestion and absorption_Homo sapiens_hsa049730.42734216
109Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.41414907
110Protein digestion and absorption_Homo sapiens_hsa049740.40540409
111Glutamatergic synapse_Homo sapiens_hsa047240.39617475
112Glucagon signaling pathway_Homo sapiens_hsa049220.39606277
113Circadian entrainment_Homo sapiens_hsa047130.39007735
114Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.38808036
115Purine metabolism_Homo sapiens_hsa002300.38663800
116Lysine degradation_Homo sapiens_hsa003100.36845090
117Dopaminergic synapse_Homo sapiens_hsa047280.36660250
118Vascular smooth muscle contraction_Homo sapiens_hsa042700.35193896
119Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.34877284
120Glycosaminoglycan degradation_Homo sapiens_hsa005310.34863015
121Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.34162775
122Fatty acid biosynthesis_Homo sapiens_hsa000610.33916257
123Prion diseases_Homo sapiens_hsa050200.33323670
124Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.32655763
125PPAR signaling pathway_Homo sapiens_hsa033200.32122629
126Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.31645971
127Ovarian steroidogenesis_Homo sapiens_hsa049130.30774804
128Arachidonic acid metabolism_Homo sapiens_hsa005900.29517320
129Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.28711230
130Drug metabolism - other enzymes_Homo sapiens_hsa009830.26441087

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