UNC119B

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1axonemal dynein complex assembly (GO:0070286)6.42488986
2lung epithelium development (GO:0060428)6.07885062
3epithelial cell fate commitment (GO:0072148)5.13587827
4motile cilium assembly (GO:0044458)4.76200196
5planar cell polarity pathway involved in neural tube closure (GO:0090179)4.69101681
6epithelial cell differentiation involved in prostate gland development (GO:0060742)4.38164542
7regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)4.32460097
8mitotic chromosome condensation (GO:0007076)4.25900926
9cilium movement (GO:0003341)4.24540135
10DNA unwinding involved in DNA replication (GO:0006268)4.20937616
11lens fiber cell development (GO:0070307)4.14370614
12pre-miRNA processing (GO:0031054)4.09450351
13negative regulation of hematopoietic progenitor cell differentiation (GO:1901533)4.03828676
14regulation of hippo signaling (GO:0035330)3.92346515
15collecting duct development (GO:0072044)3.69940601
16protein complex localization (GO:0031503)3.64730692
17lysine metabolic process (GO:0006553)3.63775376
18lysine catabolic process (GO:0006554)3.63775376
19regulation of chromatin binding (GO:0035561)3.59734234
20mitotic sister chromatid cohesion (GO:0007064)3.55089278
21heterochromatin organization (GO:0070828)3.54721622
22midgut development (GO:0007494)3.53823593
23epithelial to mesenchymal transition involved in endocardial cushion formation (GO:0003198)3.51971392
24regulation of epithelial cell proliferation involved in prostate gland development (GO:0060768)3.51330710
25Notch signaling involved in heart development (GO:0061314)3.51073724
26cell wall macromolecule catabolic process (GO:0016998)3.48702922
27cell wall macromolecule metabolic process (GO:0044036)3.48702922
28COPI coating of Golgi vesicle (GO:0048205)3.44662656
29Golgi transport vesicle coating (GO:0048200)3.44662656
30left/right pattern formation (GO:0060972)3.43275933
31fusion of sperm to egg plasma membrane (GO:0007342)3.41282719
32convergent extension (GO:0060026)3.40188385
33epithelial cilium movement (GO:0003351)3.38581057
34renal system development (GO:0072001)3.36787732
35histone H3-K36 demethylation (GO:0070544)3.35875151
36chondrocyte proliferation (GO:0035988)3.32683096
37endocardial cushion morphogenesis (GO:0003203)3.31390599
38establishment of monopolar cell polarity (GO:0061162)3.30866392
39establishment or maintenance of monopolar cell polarity (GO:0061339)3.30866392
40cellular protein complex localization (GO:0034629)3.28306932
41regulation of extracellular matrix organization (GO:1903053)3.28013256
42cell migration involved in heart development (GO:0060973)3.23552433
43regulation of RNA export from nucleus (GO:0046831)3.21836232
44serine family amino acid catabolic process (GO:0009071)3.20543687
45apoptotic process involved in morphogenesis (GO:0060561)3.19349234
46coronary vasculature morphogenesis (GO:0060977)3.19330565
47gene silencing by RNA (GO:0031047)3.18707198
48urate metabolic process (GO:0046415)3.18223925
49Wnt signaling pathway, planar cell polarity pathway (GO:0060071)3.17435376
50establishment or maintenance of apical/basal cell polarity (GO:0035088)3.17162273
51establishment or maintenance of bipolar cell polarity (GO:0061245)3.17162273
52embryonic foregut morphogenesis (GO:0048617)3.14851829
53regulation of endothelial cell chemotaxis (GO:2001026)3.13535964
54venous blood vessel morphogenesis (GO:0048845)3.09585639
55RNA stabilization (GO:0043489)3.08799757
56mRNA stabilization (GO:0048255)3.08799757
57glycine metabolic process (GO:0006544)3.07439178
58embryonic camera-type eye development (GO:0031076)3.06008181
59apical protein localization (GO:0045176)3.05934592
60axon extension involved in axon guidance (GO:0048846)3.05442018
61neuron projection extension involved in neuron projection guidance (GO:1902284)3.05442018
62notochord development (GO:0030903)3.03709152
63regulation of gene silencing by RNA (GO:0060966)3.01939490
64regulation of posttranscriptional gene silencing (GO:0060147)3.01939490
65regulation of gene silencing by miRNA (GO:0060964)3.01939490
66drug transmembrane transport (GO:0006855)3.01804396
67regulation of establishment of planar polarity (GO:0090175)3.01725990
68DNA synthesis involved in DNA repair (GO:0000731)2.99922490
69glyoxylate metabolic process (GO:0046487)2.98510105
70body morphogenesis (GO:0010171)2.97511187
71paraxial mesoderm development (GO:0048339)2.95431269
72cysteine metabolic process (GO:0006534)2.94305929
73positive regulation of transcription from RNA polymerase II promoter in response to stress (GO:003602.93756214
74serine family amino acid metabolic process (GO:0009069)2.93468787
75histone H3-K9 demethylation (GO:0033169)2.93241714
76exocrine pancreas development (GO:0031017)2.93093127
77fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540)2.92862799
78epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)2.91724694
79establishment of planar polarity (GO:0001736)2.91554191
80establishment of tissue polarity (GO:0007164)2.91554191
81protein-DNA complex disassembly (GO:0032986)2.91057725
82nucleosome disassembly (GO:0006337)2.91057725
83embryonic body morphogenesis (GO:0010172)2.90296504
84amino-acid betaine metabolic process (GO:0006577)2.87951009
85heart valve formation (GO:0003188)2.87177578
86nuclear pore complex assembly (GO:0051292)2.86850717
87regulation of nucleobase-containing compound transport (GO:0032239)2.86424239
88chromosome condensation (GO:0030261)2.86178522
89nuclear pore organization (GO:0006999)2.85713207
90mesenchymal to epithelial transition involved in metanephros morphogenesis (GO:0003337)2.85463447
91negative regulation of mRNA splicing, via spliceosome (GO:0048025)2.83891273
92regulation of cholesterol homeostasis (GO:2000188)2.83181730
93camera-type eye morphogenesis (GO:0048593)2.82496417
94atrioventricular valve morphogenesis (GO:0003181)2.78606827
95adherens junction assembly (GO:0034333)2.78394153
96tricarboxylic acid metabolic process (GO:0072350)2.76481019
97activation of signaling protein activity involved in unfolded protein response (GO:0006987)2.74285486
98positive regulation of tyrosine phosphorylation of Stat1 protein (GO:0042511)2.73232931
99serine family amino acid biosynthetic process (GO:0009070)2.73209834
100mRNA cleavage (GO:0006379)2.72209619
101positive regulation of nuclease activity (GO:0032075)2.71219509
102alpha-linolenic acid metabolic process (GO:0036109)2.70148536
103type B pancreatic cell development (GO:0003323)2.69178082
104L-phenylalanine metabolic process (GO:0006558)2.68862582
105erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)2.68862582
106pore complex assembly (GO:0046931)2.68098553
107eye morphogenesis (GO:0048592)2.67451445
108regulation of NFAT protein import into nucleus (GO:0051532)2.67094747
1094-hydroxyproline metabolic process (GO:0019471)2.66206003
110regulation of branching involved in prostate gland morphogenesis (GO:0060687)2.65287342
111folic acid-containing compound biosynthetic process (GO:0009396)2.65084352
112maintenance of protein localization in endoplasmic reticulum (GO:0035437)2.63881520
113hippo signaling (GO:0035329)2.63328045
114spliceosomal tri-snRNP complex assembly (GO:0000244)2.61745528
115asymmetric protein localization (GO:0008105)2.61347874
116establishment or maintenance of epithelial cell apical/basal polarity (GO:0045197)2.60638404
117non-canonical Wnt signaling pathway (GO:0035567)2.60013506
118focal adhesion assembly (GO:0048041)2.58706643
119cell-substrate adherens junction assembly (GO:0007045)2.58706643
120glomerular epithelial cell development (GO:0072310)2.57621687
121dosage compensation (GO:0007549)2.57612787
122protein retention in ER lumen (GO:0006621)2.57496654
123regulation of translational termination (GO:0006449)2.57488805
124proline biosynthetic process (GO:0006561)2.56213552
125ventricular system development (GO:0021591)2.55957219
126mesenchyme morphogenesis (GO:0072132)2.55933019
127DNA topological change (GO:0006265)2.55460753
128negative regulation of glial cell proliferation (GO:0060253)2.55225106
129regulation of mRNA stability (GO:0043488)2.54979397
130positive regulation of smoothened signaling pathway (GO:0045880)2.54457469
131homocysteine metabolic process (GO:0050667)2.52920670
132phosphate ion transport (GO:0006817)2.52867708
133cellular response to epidermal growth factor stimulus (GO:0071364)2.52655671
134apoptotic process involved in development (GO:1902742)2.52010106
135positive regulation of epithelial to mesenchymal transition (GO:0010718)2.51881440
136erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)2.51044227
137L-phenylalanine catabolic process (GO:0006559)2.51044227
138regulation of translational fidelity (GO:0006450)2.50767738
139regulation of stem cell maintenance (GO:2000036)2.50209674
140cytoskeletal anchoring at plasma membrane (GO:0007016)2.49901085
141quaternary ammonium group transport (GO:0015697)2.49565831
142regulation of nuclease activity (GO:0032069)2.49523703
143positive regulation of keratinocyte differentiation (GO:0045618)2.48830356
144regulation of sister chromatid cohesion (GO:0007063)2.48596840
145positive regulation of BMP signaling pathway (GO:0030513)2.46799347
146maternal placenta development (GO:0001893)2.46647166
147protein localization to chromosome, centromeric region (GO:0071459)2.46254128
148regulation of mammary gland epithelial cell proliferation (GO:0033599)2.45882127
149negative regulation of cholesterol transport (GO:0032375)2.45840378
150negative regulation of sterol transport (GO:0032372)2.45840378
151drug transport (GO:0015893)2.45460051
152vitamin transmembrane transport (GO:0035461)2.44600952
153organic cation transport (GO:0015695)2.44236503
154embryonic eye morphogenesis (GO:0048048)2.42644137
155amino-acid betaine transport (GO:0015838)2.41835675
156carnitine transport (GO:0015879)2.41835675
157pentose-phosphate shunt (GO:0006098)2.41717409
158positive regulation of extracellular matrix organization (GO:1903055)2.41427489
159gene silencing (GO:0016458)2.40823046
160glandular epithelial cell development (GO:0002068)2.40711450
161endoderm development (GO:0007492)2.40416726
162protein export from nucleus (GO:0006611)2.40093456
163embryonic camera-type eye morphogenesis (GO:0048596)2.39982455
164peptidyl-lysine dimethylation (GO:0018027)2.39124954
165negative regulation of cell fate specification (GO:0009996)2.38996178
166negative regulation of chondrocyte differentiation (GO:0032331)2.37469701
167sulfur amino acid catabolic process (GO:0000098)2.36525385
168DNA packaging (GO:0006323)2.36445054
169dichotomous subdivision of an epithelial terminal unit (GO:0060600)2.36399171
170valine metabolic process (GO:0006573)2.35733485
171primary alcohol catabolic process (GO:0034310)2.34774811
172sister chromatid segregation (GO:0000819)2.34758083
173establishment of integrated proviral latency (GO:0075713)2.34669520
174DNA duplex unwinding (GO:0032508)2.34398083
175negative regulation of DNA repair (GO:0045738)2.33860049
176histone lysine demethylation (GO:0070076)2.33736667
177barbed-end actin filament capping (GO:0051016)2.33252072
178establishment of apical/basal cell polarity (GO:0035089)2.32343710
179positive regulation of catenin import into nucleus (GO:0035413)2.32328143
180retrograde vesicle-mediated transport, Golgi to ER (GO:0006890)2.31524808
181mitotic sister chromatid segregation (GO:0000070)2.30803783
182cilium or flagellum-dependent cell motility (GO:0001539)2.30654875
183regulation of catenin import into nucleus (GO:0035412)2.28824134
184regulation of RNA stability (GO:0043487)2.28512568
185epithelial cell-cell adhesion (GO:0090136)2.28095527
186neural tube closure (GO:0001843)2.28027225

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1FOXM1_23109430_ChIP-Seq_U2OS_Human4.46094485
2MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse4.20791659
3E2F7_22180533_ChIP-Seq_HELA_Human3.89880468
4EGR1_19374776_ChIP-ChIP_THP-1_Human3.04905266
5ESR1_17901129_ChIP-ChIP_LIVER_Mouse2.98988324
6MYC_22102868_ChIP-Seq_BL_Human2.84485311
7TP63_17297297_ChIP-ChIP_HaCaT_Human2.52118606
8PPARA_22158963_ChIP-Seq_LIVER_Mouse2.45321180
9RXR_22158963_ChIP-Seq_LIVER_Mouse2.36514303
10BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse2.31313470
11NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.21555663
12EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.05009399
13TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse2.00810962
14WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.98630962
15FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.95215918
16HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.92216716
17RBPJ_22232070_ChIP-Seq_NCS_Mouse1.91490649
18AR_21909140_ChIP-Seq_LNCAP_Human1.89549265
19MYC_18555785_ChIP-Seq_MESCs_Mouse1.85043290
20TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.82974151
21VDR_21846776_ChIP-Seq_THP-1_Human1.70673466
22CLOCK_20551151_ChIP-Seq_293T_Human1.68282670
23LXR_22158963_ChIP-Seq_LIVER_Mouse1.64905618
24XRN2_22483619_ChIP-Seq_HELA_Human1.64124785
25EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.58827375
26FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.58143536
27DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.57708584
28MYC_19079543_ChIP-ChIP_MESCs_Mouse1.57488011
29TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.54574724
30TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.53178742
31LXR_22292898_ChIP-Seq_THP-1_Human1.52351884
32KDM2B_26808549_Chip-Seq_K562_Human1.50930919
33ELK3_25401928_ChIP-Seq_HUVEC_Human1.50855468
34TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.50502454
35CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.50312042
36PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.50148091
37TCF7_22412390_ChIP-Seq_EML_Mouse1.50032600
38POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.47661404
39HIF1A_21447827_ChIP-Seq_MCF-7_Human1.46753365
40SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.44449263
41PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.44268596
42KLF4_18555785_ChIP-Seq_MESCs_Mouse1.43420329
43KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.40346260
44RUNX1_27514584_Chip-Seq_MCF-7_Human1.38407250
45CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.36832261
46KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.35882859
47STAT6_21828071_ChIP-Seq_BEAS2B_Human1.35767847
48ZFX_18555785_ChIP-Seq_MESCs_Mouse1.34960799
49DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.34627522
50SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.34437990
51SOX2_27498859_Chip-Seq_STOMACH_Mouse1.33955191
52ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.33479319
53RARG_19884340_ChIP-ChIP_MEFs_Mouse1.33395319
54E2F4_17652178_ChIP-ChIP_JURKAT_Human1.31987423
55STAT3_1855785_ChIP-Seq_MESCs_Mouse1.31384005
56KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.31345026
57* CREB1_26743006_Chip-Seq_LNCaP_Human1.30624833
58NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.30112775
59NELFA_20434984_ChIP-Seq_ESCs_Mouse1.29922616
60KDM2B_26808549_Chip-Seq_DND41_Human1.28920008
61CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.27801194
62KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.25065169
63KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.25065169
64KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.25065169
65ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.25055506
66TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.24935062
67KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.24878355
68MAF_26560356_Chip-Seq_TH1_Human1.22121623
69MYCN_18555785_ChIP-Seq_MESCs_Mouse1.21126826
70* CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.20735457
71FOXO3_23340844_ChIP-Seq_DLD1_Human1.20485343
72POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.19614391
73MYC_18358816_ChIP-ChIP_MESCs_Mouse1.18056811
74SMC4_20622854_ChIP-Seq_HELA_Human1.17952298
75ATF3_27146783_Chip-Seq_COLON_Human1.17831302
76KDM2B_26808549_Chip-Seq_JURKAT_Human1.16647881
77RACK7_27058665_Chip-Seq_MCF-7_Human1.16399162
78TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.16174748
79SREBP2_21459322_ChIP-Seq_LIVER_Mouse1.15935401
80* MYC_19030024_ChIP-ChIP_MESCs_Mouse1.15668954
81SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.14315198
82ELF1_20517297_ChIP-Seq_JURKAT_Human1.12952075
83RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.12919550
84ESR2_21235772_ChIP-Seq_MCF-7_Human1.12560736
85CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.12359203
86CIITA_25753668_ChIP-Seq_RAJI_Human1.11819326
87TCFCP2L1_18555785_ChIP-Seq_MESCs_Mouse1.10934963
88KAP1_27257070_Chip-Seq_ESCs_Mouse1.10763327
89NANOG_21062744_ChIP-ChIP_HESCs_Human1.10643963
90FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human1.10351266
91ERG_21242973_ChIP-ChIP_JURKAT_Human1.10134258
92EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.08814594
93P68_20966046_ChIP-Seq_HELA_Human1.08733375
94ESR1_15608294_ChIP-ChIP_MCF-7_Human1.08068520
95CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.07180061
96SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.06788410
97TP53_22127205_ChIP-Seq_IMR90_Human1.06572425
98NACC1_18358816_ChIP-ChIP_MESCs_Mouse1.05914490
99UTX_26944678_Chip-Seq_JUKART_Human1.05909276
100NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.05556609
101KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.05053480
102SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.04418821
103HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse1.03742930
104TP63_19390658_ChIP-ChIP_HaCaT_Human1.03559858
105E2F1_21310950_ChIP-Seq_MCF-7_Human1.03434245
106TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.03333319
107UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.03125834
108ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.02988930
109NCOR1_26117541_ChIP-Seq_K562_Human1.02399454
110KDM5A_27292631_Chip-Seq_BREAST_Human1.02310657
111WT1_19549856_ChIP-ChIP_CCG9911_Human1.02019791
112ESR1_20079471_ChIP-ChIP_T-47D_Human1.01781616
113E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.00554752
114ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.00546039
115NANOG_18555785_ChIP-Seq_MESCs_Mouse0.99888939
116ZIC3_20872845_ChIP-ChIP_MESCs_Mouse0.99661204
117NOTCH1_21737748_ChIP-Seq_TLL_Human0.98457850
118KDM2B_26808549_Chip-Seq_SUP-B15_Human0.98189703
119ZFP281_18757296_ChIP-ChIP_E14_Mouse0.97969335
120KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human0.96666819
121* ZFP281_27345836_Chip-Seq_ESCs_Mouse0.95035814
122TET1_21451524_ChIP-Seq_MESCs_Mouse0.94858070
123CEBPB_23403033_ChIP-Seq_LIVER_Mouse0.94348480
124TCF3_18692474_ChIP-Seq_MEFs_Mouse0.94212681
125P300_27058665_Chip-Seq_ZR-75-30cells_Human0.92570326
126BRD4_27068464_Chip-Seq_AML-cells_Mouse0.92524164
127ESR1_21235772_ChIP-Seq_MCF-7_Human0.91552015
128CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.91008487
129GABP_19822575_ChIP-Seq_HepG2_Human0.88615809
130KDM5B_21448134_ChIP-Seq_MESCs_Mouse0.88516043
131CHD1_26751641_Chip-Seq_LNCaP_Human0.87760770
132ZNF263_19887448_ChIP-Seq_K562_Human0.87618141
133MYBL2_22936984_ChIP-ChIP_MESCs_Mouse0.86494839
134TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.86325972
135MAF_26560356_Chip-Seq_TH2_Human0.85983083
136SRY_22984422_ChIP-ChIP_TESTIS_Rat0.85922690
137GATA6_25053715_ChIP-Seq_YYC3_Human0.85615445
138HNF4A_19761587_ChIP-ChIP_CACO-2_Human0.85105850

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0000566_synostosis4.33641850
2MP0010030_abnormal_orbit_morphology3.84676841
3MP0009780_abnormal_chondrocyte_physiolo3.61469913
4MP0005360_urolithiasis3.16294246
5MP0003705_abnormal_hypodermis_morpholog2.81214881
6MP0002139_abnormal_hepatobiliary_system2.79012201
7MP0008961_abnormal_basal_metabolism2.23616650
8MP0005365_abnormal_bile_salt2.22520788
9MP0002653_abnormal_ependyma_morphology2.21898393
10MP0005409_darkened_coat_color2.17879817
11MP0010352_gastrointestinal_tract_polyps1.93694335
12MP0003283_abnormal_digestive_organ1.92344166
13MP0003941_abnormal_skin_development1.89018979
14MP0001958_emphysema1.87551785
15MP0004272_abnormal_basement_membrane1.87482981
16MP0004858_abnormal_nervous_system1.80576646
17MP0002877_abnormal_melanocyte_morpholog1.77618504
18MP0003300_gastrointestinal_ulcer1.75255664
19MP0002089_abnormal_postnatal_growth/wei1.74624998
20MP0009053_abnormal_anal_canal1.69952192
21MP0002697_abnormal_eye_size1.69297635
22MP0003252_abnormal_bile_duct1.66107607
23MP0005076_abnormal_cell_differentiation1.65627695
24MP0001346_abnormal_lacrimal_gland1.61259244
25MP0005257_abnormal_intraocular_pressure1.59723432
26MP0003942_abnormal_urinary_system1.57818838
27MP0002009_preneoplasia1.53854305
28MP0001730_embryonic_growth_arrest1.53021193
29MP0005248_abnormal_Harderian_gland1.52925205
30MP0002234_abnormal_pharynx_morphology1.52878392
31MP0005332_abnormal_amino_acid1.52621260
32MP0003111_abnormal_nucleus_morphology1.52019494
33MP0004185_abnormal_adipocyte_glucose1.50326939
34MP0000428_abnormal_craniofacial_morphol1.50307351
35MP0003890_abnormal_embryonic-extraembry1.48269854
36MP0004043_abnormal_pH_regulation1.47738170
37MP0008057_abnormal_DNA_replication1.47442294
38MP0009643_abnormal_urine_homeostasis1.45705381
39MP0000537_abnormal_urethra_morphology1.44761164
40MP0009379_abnormal_foot_pigmentation1.44289652
41MP0005085_abnormal_gallbladder_physiolo1.42427016
42MP0003937_abnormal_limbs/digits/tail_de1.41927065
43MP0005220_abnormal_exocrine_pancreas1.40085915
44MP0002084_abnormal_developmental_patter1.38177758
45MP0000534_abnormal_ureter_morphology1.37183269
46MP0003984_embryonic_growth_retardation1.37068707
47MP0001293_anophthalmia1.36209123
48MP0002796_impaired_skin_barrier1.35274103
49MP0002088_abnormal_embryonic_growth/wei1.34247886
50MP0001697_abnormal_embryo_size1.33782607
51MP0009703_decreased_birth_body1.33307913
52MP0002138_abnormal_hepatobiliary_system1.32178559
53MP0002233_abnormal_nose_morphology1.31139963
54MP0003115_abnormal_respiratory_system1.31018822
55MP0000762_abnormal_tongue_morphology1.30944060
56MP0005380_embryogenesis_phenotype1.30704827
57MP0001672_abnormal_embryogenesis/_devel1.30704827
58MP0004019_abnormal_vitamin_homeostasis1.29689112
59MP0002249_abnormal_larynx_morphology1.28848634
60MP0003315_abnormal_perineum_morphology1.28125963
61MP0004957_abnormal_blastocyst_morpholog1.27803671
62MP0010234_abnormal_vibrissa_follicle1.27205948
63MP0006054_spinal_hemorrhage1.27138768
64MP0003077_abnormal_cell_cycle1.27071723
65MP0002102_abnormal_ear_morphology1.25337219
66MP0002092_abnormal_eye_morphology1.23357452
67MP0000432_abnormal_head_morphology1.22151187
68MP0008875_abnormal_xenobiotic_pharmacok1.21117818
69MP0004233_abnormal_muscle_weight1.18855766
70MP0010678_abnormal_skin_adnexa1.18795665
71MP0008438_abnormal_cutaneous_collagen1.17290059
72MP0010094_abnormal_chromosome_stability1.16571759
73MP0002086_abnormal_extraembryonic_tissu1.16534577
74MP0002085_abnormal_embryonic_tissue1.16146898
75MP0000350_abnormal_cell_proliferation1.15832143
76MP0002116_abnormal_craniofacial_bone1.14365643
77MP0004197_abnormal_fetal_growth/weight/1.14057561
78MP0003453_abnormal_keratinocyte_physiol1.13717574
79MP0003806_abnormal_nucleotide_metabolis1.13669476
80MP0003861_abnormal_nervous_system1.13091725
81MP0001849_ear_inflammation1.12163256
82MP0010307_abnormal_tumor_latency1.11440068
83MP0003119_abnormal_digestive_system1.09044825
84MP0005501_abnormal_skin_physiology1.07809685
85MP0003693_abnormal_embryo_hatching1.07597689
86MP0010368_abnormal_lymphatic_system1.06253205
87MP0003566_abnormal_cell_adhesion1.05316641
88MP0003123_paternal_imprinting1.05138056
89MP0002136_abnormal_kidney_physiology1.04379609
90MP0000579_abnormal_nail_morphology1.03928751
91MP0003385_abnormal_body_wall1.03839610
92MP0000609_abnormal_liver_physiology1.02740330
93MP0005023_abnormal_wound_healing1.02512355
94MP0003195_calcinosis1.02359487
95MP0008932_abnormal_embryonic_tissue1.02275881
96MP0002132_abnormal_respiratory_system1.00762621
97MP0001915_intracranial_hemorrhage1.00404706
98MP0009250_abnormal_appendicular_skeleto0.98643493
99MP0002928_abnormal_bile_duct0.98041499
100MP0002160_abnormal_reproductive_system0.98001280
101MP0003755_abnormal_palate_morphology0.97932054
102MP0001756_abnormal_urination0.97257208
103MP0000733_abnormal_muscle_development0.97138968
104MP0002080_prenatal_lethality0.96885317
105MP0004264_abnormal_extraembryonic_tissu0.95450509
106MP0008007_abnormal_cellular_replicative0.94855022
107MP0002060_abnormal_skin_morphology0.93628089
108MP0001286_abnormal_eye_development0.93434799
109MP0005503_abnormal_tendon_morphology0.93042880
110MP0003091_abnormal_cell_migration0.92381605
111MP0002282_abnormal_trachea_morphology0.92133183
112MP0000462_abnormal_digestive_system0.91536171
113MP0005394_taste/olfaction_phenotype0.91527293
114MP0005499_abnormal_olfactory_system0.91527293
115MP0008789_abnormal_olfactory_epithelium0.91513846
116MP0001299_abnormal_eye_distance/0.91293448
117MP0002896_abnormal_bone_mineralization0.90339012
118MP0004782_abnormal_surfactant_physiolog0.89671653
119MP0003878_abnormal_ear_physiology0.88431712
120MP0005377_hearing/vestibular/ear_phenot0.88431712
121MP0003938_abnormal_ear_development0.85790739
122MP0000003_abnormal_adipose_tissue0.85434069
123MP0000049_abnormal_middle_ear0.85234886
124MP0009840_abnormal_foam_cell0.82435899
125MP0002111_abnormal_tail_morphology0.82132506
126MP0003183_abnormal_peptide_metabolism0.81773405
127MP0004133_heterotaxia0.81490466
128MP0000377_abnormal_hair_follicle0.81096674
129MP0000678_abnormal_parathyroid_gland0.79971429
130MP0010329_abnormal_lipoprotein_level0.79936840
131MP0001944_abnormal_pancreas_morphology0.79603820
132MP0009278_abnormal_bone_marrow0.79375833
133MP0001666_abnormal_nutrient_absorption0.78728713
134MP0000598_abnormal_liver_morphology0.75778068
135MP0000163_abnormal_cartilage_morphology0.74020201
136MP0000490_abnormal_crypts_of0.74004689
137MP0000685_abnormal_immune_system0.71225279
138MP0004808_abnormal_hematopoietic_stem0.70697339
139MP0001929_abnormal_gametogenesis0.70617500
140MP0002019_abnormal_tumor_incidence0.67809166
141MP0002269_muscular_atrophy0.67437098
142MP0005319_abnormal_enzyme/_coenzyme0.67330967
143MP0005423_abnormal_somatic_nervous0.66305247
144MP0003935_abnormal_craniofacial_develop0.65836843
145MP0005375_adipose_tissue_phenotype0.65503351
146MP0000467_abnormal_esophagus_morphology0.65476664
147MP0009672_abnormal_birth_weight0.65215457
148MP0001145_abnormal_male_reproductive0.65085050
149MP0000477_abnormal_intestine_morphology0.65042022
150MP0005623_abnormal_meninges_morphology0.64564970
151MP0005670_abnormal_white_adipose0.64317482

Predicted human phenotypes

RankGene SetZ-score
1Abnormal respiratory motile cilium physiology (HP:0012261)5.24140922
2Abnormal ciliary motility (HP:0012262)5.13761101
3Abnormal respiratory motile cilium morphology (HP:0005938)5.07972041
4Abnormal respiratory epithelium morphology (HP:0012253)5.07972041
5Rhinitis (HP:0012384)4.71119385
6Dynein arm defect of respiratory motile cilia (HP:0012255)4.53579125
7Absent/shortened dynein arms (HP:0200106)4.53579125
8Neonatal short-limb short stature (HP:0008921)4.50674029
9Hyperacusis (HP:0010780)4.47850317
10Elfin facies (HP:0004428)4.34815565
11Renal duplication (HP:0000075)3.78758467
12Increased nuchal translucency (HP:0010880)3.73888625
13Renovascular hypertension (HP:0100817)3.68998418
14Overriding aorta (HP:0002623)3.50774473
15Gout (HP:0001997)3.43623458
16Bronchiectasis (HP:0002110)3.24449168
17Nasal polyposis (HP:0100582)3.04978205
18Heterotopia (HP:0002282)3.01659365
19Polygenic inheritance (HP:0010982)2.96205129
20Insomnia (HP:0100785)2.95126002
21Toxemia of pregnancy (HP:0100603)2.81908017
22Partial duplication of thumb phalanx (HP:0009944)2.80957802
23Hypercalciuria (HP:0002150)2.80231206
24Hallux valgus (HP:0001822)2.76198976
25Spastic diplegia (HP:0001264)2.71174162
26Abnormality of the costochondral junction (HP:0000919)2.70256677
27Visceral angiomatosis (HP:0100761)2.70014056
28Atelectasis (HP:0100750)2.68670210
29Male infertility (HP:0003251)2.67414353
30Flat cornea (HP:0007720)2.63500144
31Abnormality of the nasal mucosa (HP:0000433)2.61357200
32Deviation of the hallux (HP:0010051)2.60598482
33Neonatal death (HP:0003811)2.60294953
34Coronal craniosynostosis (HP:0004440)2.54968128
35Partial duplication of the phalanx of hand (HP:0009999)2.54787520
36Cone-shaped epiphyses of the phalanges of the hand (HP:0010230)2.54630458
37Hemangiomatosis (HP:0007461)2.53368556
38Turricephaly (HP:0000262)2.47604714
39Broad distal phalanx of finger (HP:0009836)2.46972248
40Abnormality of dentin (HP:0010299)2.44939450
41Flat acetabular roof (HP:0003180)2.41949480
42Chronic bronchitis (HP:0004469)2.41312748
43Protrusio acetabuli (HP:0003179)2.39573080
44Short nail (HP:0001799)2.38226862
45Arnold-Chiari malformation (HP:0002308)2.37972200
46Hand muscle atrophy (HP:0009130)2.37807487
47Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)2.37620173
48Abnormality of the diencephalon (HP:0010662)2.35543387
49Infertility (HP:0000789)2.34491760
50Bicuspid aortic valve (HP:0001647)2.30991512
51Shallow orbits (HP:0000586)2.28150286
52Bowel diverticulosis (HP:0005222)2.26533399
53Metaphyseal cupping (HP:0003021)2.26316828
54Esophageal varix (HP:0002040)2.25919160
55Ulnar bowing (HP:0003031)2.25192758
56Bladder diverticulum (HP:0000015)2.22964058
57Asymmetry of the thorax (HP:0001555)2.21347279
58Megalocornea (HP:0000485)2.19939991
59Megalencephaly (HP:0001355)2.19495024
60Hyperglycinuria (HP:0003108)2.19477624
61Abnormality of glycine metabolism (HP:0010895)2.17376697
62Abnormality of serine family amino acid metabolism (HP:0010894)2.17376697
63Ankyloglossia (HP:0010296)2.16647092
64Vertebral arch anomaly (HP:0008438)2.14255977
65Aortic aneurysm (HP:0004942)2.13783388
66Nephrocalcinosis (HP:0000121)2.07074659
67Missing ribs (HP:0000921)2.06144345
68Abnormality of the distal phalanx of the thumb (HP:0009617)2.05864749
69Absent frontal sinuses (HP:0002688)2.04459290
70Polyuria (HP:0000103)2.04265821
71Rhizomelia (HP:0008905)2.02607516
72Premature rupture of membranes (HP:0001788)2.02268766
73Abnormality of pyrimidine metabolism (HP:0004353)2.01934820
74Hyperglycinemia (HP:0002154)2.01203403
75Obstructive sleep apnea (HP:0002870)2.00984111
76Ketosis (HP:0001946)2.00362821
77Hyperactive renin-angiotensin system (HP:0000841)1.99717943
78Abnormality of nucleobase metabolism (HP:0010932)1.99356830
79Increased purine levels (HP:0004368)1.98816326
80Hyperuricemia (HP:0002149)1.98816326
81Adactyly (HP:0009776)1.98746340
82Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)1.98347301
83Abnormality of purine metabolism (HP:0004352)1.98067835
84Abnormal urine output (HP:0012590)1.98001682
85Camptodactyly of toe (HP:0001836)1.97648128
86Abnormality of glutamine family amino acid metabolism (HP:0010902)1.96529798
87Hypoglycemic coma (HP:0001325)1.95079186
88Abnormality of the middle phalanges of the toes (HP:0010183)1.94699098
89Abnormality of the salivary glands (HP:0010286)1.92760903
90Duplication of thumb phalanx (HP:0009942)1.92739732
91Abnormality of renal excretion (HP:0011036)1.92107630
92Increased circulating renin level (HP:0000848)1.91134291
93Malignant gastrointestinal tract tumors (HP:0006749)1.91034334
94Gastrointestinal carcinoma (HP:0002672)1.91034334
95Aplasia involving bones of the upper limbs (HP:0009823)1.90410053
96Aplasia of the phalanges of the hand (HP:0009802)1.90410053
97Aplasia involving bones of the extremities (HP:0009825)1.90410053
98Bell-shaped thorax (HP:0001591)1.90156926
99Abnormality of the dental root (HP:0006486)1.88807326
100Taurodontia (HP:0000679)1.88807326
101Abnormality of permanent molar morphology (HP:0011071)1.88807326
102Ketoacidosis (HP:0001993)1.87643040
103Abnormality of the musculature of the hand (HP:0001421)1.86852748
104Recurrent otitis media (HP:0000403)1.86392520
105Aplasia/Hypoplasia of the phalanges of the thumb (HP:0009658)1.86256634
106Hypercalcemia (HP:0003072)1.86036103
107Hypoplastic toenails (HP:0001800)1.85563819
108Hypokalemic alkalosis (HP:0001949)1.85165278
109Late onset (HP:0003584)1.84563551
110Back pain (HP:0003418)1.83771069
111Chronic otitis media (HP:0000389)1.83600983
112Upper limb amyotrophy (HP:0009129)1.82504474
113Distal upper limb amyotrophy (HP:0007149)1.82504474
114Broad metatarsal (HP:0001783)1.82019636
115Hereditary nonpolyposis colorectal carcinoma (HP:0006716)1.81262815
116Abnormality of monocarboxylic acid metabolism (HP:0010996)1.79784293
117Respiratory insufficiency due to defective ciliary clearance (HP:0200073)1.79398931
118Abnormality of molar morphology (HP:0011070)1.79179061
119Abnormality of molar (HP:0011077)1.79179061
120Abnormality of the phalanges of the hallux (HP:0010057)1.79006421
121Bifid scrotum (HP:0000048)1.78704759
122Abnormality of the lumbar spine (HP:0100712)1.78547262
123Leiomyosarcoma (HP:0100243)1.77725509
124Uterine leiomyosarcoma (HP:0002891)1.77725509
125High anterior hairline (HP:0009890)1.77670388
126Deep venous thrombosis (HP:0002625)1.77604969
127Bronchitis (HP:0012387)1.77245240
128Aneurysm (HP:0002617)1.77103360
129Abnormality of the distal phalanges of the toes (HP:0010182)1.77059932
130Long palpebral fissure (HP:0000637)1.76820411
131Chondrocalcinosis (HP:0000934)1.76588806
132Nephrolithiasis (HP:0000787)1.74773319
133Spinal cord lesions (HP:0100561)1.74015942
134Syringomyelia (HP:0003396)1.74015942
135Abnormality involving the epiphyses of the upper limbs (HP:0003839)1.72948586
136Abnormality of the gastric mucosa (HP:0004295)1.70872473
137Arterial tortuosity (HP:0005116)1.70369984
138Bronchomalacia (HP:0002780)1.69820431
139Abnormality of chloride homeostasis (HP:0011422)1.69636132
140Cerebral aneurysm (HP:0004944)1.66903761
141Dysmetric saccades (HP:0000641)1.66899741
142Abnormality of oral frenula (HP:0000190)1.66746172
143Abnormality of aromatic amino acid family metabolism (HP:0004338)1.65837547
144Absent radius (HP:0003974)1.65456550
145Aplasia/Hypoplasia involving the sinuses (HP:0009120)1.64893756
146Cardiomegaly (HP:0001640)1.64541115
147Vascular tortuosity (HP:0004948)1.64365940
148Abnormality of the calcaneus (HP:0008364)1.64223339
149Occipital encephalocele (HP:0002085)1.63350044
150Flattened epiphyses (HP:0003071)1.61677706
151Pseudobulbar signs (HP:0002200)1.60810394
152Broad finger (HP:0001500)1.60755965
153Germ cell neoplasia (HP:0100728)1.59306702
154Broad thumb (HP:0011304)1.58235874
155Advanced eruption of teeth (HP:0006288)1.56635532
156Broad phalanges of the hand (HP:0009768)1.55587130
157Mitral valve prolapse (HP:0001634)1.55169286
158Anal stenosis (HP:0002025)1.54621448
159Abnormality of the dental pulp (HP:0006479)1.54369845
160Facial cleft (HP:0002006)1.53802109
161Deviation of the thumb (HP:0009603)1.53767854
162Macroorchidism (HP:0000053)1.52576867
163Genu recurvatum (HP:0002816)1.52091449
164Thin ribs (HP:0000883)1.51817473
165Broad palm (HP:0001169)1.51795206
166Transposition of the great arteries (HP:0001669)1.50891636
167Abnormal connection of the cardiac segments (HP:0011545)1.50891636
168Abnormal ventriculo-arterial connection (HP:0011563)1.50891636
169Enlarged penis (HP:0000040)1.50529336
170Broad face (HP:0000283)1.50499513
171Disproportionate tall stature (HP:0001519)1.49266345
172Overlapping toe (HP:0001845)1.48709116

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BUB14.93420001
2SMG13.98502169
3TRIB33.43776327
4MAP3K103.04947408
5FGFR32.89672128
6ERN12.55399222
7CDK122.48996935
8EEF2K2.48640418
9PKN22.45686283
10PNCK2.29237759
11NEK22.23161620
12FGFR42.10422580
13WNK31.94069944
14PASK1.85869630
15WNK41.81713949
16PDK41.78018213
17PDK31.78018213
18FGFR11.72828280
19CAMK1G1.69749265
20BCKDK1.64339419
21MET1.61227781
22MAP4K11.51063279
23NEK11.47614633
24PRPF4B1.45422921
25PTK61.44845174
26PAK41.36731594
27STK101.35201016
28RIPK11.34956383
29CDK41.34265993
30SIK11.29941556
31DYRK31.29012943
32MELK1.26689857
33PDGFRA1.25771684
34LRRK21.24999385
35TESK21.23276743
36KSR21.21917621
37MTOR1.19900025
38MAP3K91.17761250
39GRK61.17742184
40NTRK11.09896692
41EPHB21.09209264
42RPS6KA41.08964929
43EPHA21.08617509
44LATS11.04274804
45ARAF1.04250624
46CAMK1D1.03713110
47MAP3K131.01344671
48TLK11.01159590
49TAF10.99936576
50TYK20.98436224
51PRKD30.97823189
52TTN0.97683659
53TTK0.96512689
54ICK0.96036082
55MAP3K70.95665539
56TESK10.95456961
57DYRK1B0.94756031
58BRAF0.94398117
59ZAP700.91626040
60STK240.89838020
61FLT30.88322645
62CDC70.86694731
63SCYL20.86622764
64MKNK10.85490467
65STK38L0.83463548
66MAP3K20.81520107
67PDGFRB0.80220787
68RET0.80193611
69MST1R0.79667404
70NEK90.78547389
71CDK90.76269255
72PDK20.75339232
73FGFR20.75303394
74CDK70.74464893
75MAP3K80.73087411
76AURKB0.72766260
77PLK10.72144368
78CDK60.71143731
79CHEK10.70500232
80STK30.68365200
81YES10.68269186
82BRD40.67822506
83RPS6KB20.66445277
84ITK0.66372428
85KSR10.65405163
86MAP3K30.64306256
87PTK20.64247783
88AKT20.63549063
89TSSK60.63478617
90ACVR1B0.63418888
91TYRO30.61713109
92TGFBR10.60459035
93EPHB10.60080227
94ALK0.59682002
95PBK0.56705662
96SRPK10.54627922
97ATR0.53356708
98TGFBR20.53025158
99LATS20.52409495
100IRAK30.51139089
101BTK0.50848705
102CSK0.50840018
103RPS6KB10.49784304
104PAK20.49536837
105IRAK20.49276938
106BMX0.48964256
107RPS6KA20.48558201
108JAK30.47776828
109STK380.47701719
110MARK20.47495767
111MAP2K30.46655326
112TAOK10.45218200
113CDK10.44747090
114BRSK20.44577223
115SGK30.44244802
116CDK80.43171933
117HIPK20.43028875
118CHEK20.42411303
119CDK190.42340498
120WEE10.42126735
121DDR20.41255871
122MAP3K110.40908916
123AURKA0.39473208
124ERBB40.39045457
125PIM10.38606252
126RPS6KL10.38085639
127RPS6KC10.38085639
128ATM0.37158206
129ROCK20.36884475
130MKNK20.36877620
131STK40.36815056
132PRKD20.36721555
133CDK20.36257955
134MAPK150.34160708
135PRKCI0.33727360
136MAPKAPK30.31211917
137JAK20.30576291
138BRSK10.30505054
139MAP2K20.30404380
140EGFR0.29892444
141EPHA30.28506042
142PRKCZ0.26434235

Predicted pathways (KEGG)

RankGene SetZ-score
1Selenocompound metabolism_Homo sapiens_hsa004502.82252779
2Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006302.29360280
3Pentose phosphate pathway_Homo sapiens_hsa000302.27446376
4Ascorbate and aldarate metabolism_Homo sapiens_hsa000532.26585093
5Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004002.19518644
6Thyroid cancer_Homo sapiens_hsa052162.13676579
7Biosynthesis of amino acids_Homo sapiens_hsa012302.00875404
8Lysine degradation_Homo sapiens_hsa003101.90136007
9Endometrial cancer_Homo sapiens_hsa052131.89685843
10Cyanoamino acid metabolism_Homo sapiens_hsa004601.89081559
11Fatty acid degradation_Homo sapiens_hsa000711.87403942
12Maturity onset diabetes of the young_Homo sapiens_hsa049501.84950743
13Nitrogen metabolism_Homo sapiens_hsa009101.83164195
14Carbon metabolism_Homo sapiens_hsa012001.82976790
15Tryptophan metabolism_Homo sapiens_hsa003801.78063636
16Primary bile acid biosynthesis_Homo sapiens_hsa001201.75265752
17Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.71637238
18Notch signaling pathway_Homo sapiens_hsa043301.71111957
19Prostate cancer_Homo sapiens_hsa052151.70339883
202-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.68094351
21Basal cell carcinoma_Homo sapiens_hsa052171.58678702
22Bladder cancer_Homo sapiens_hsa052191.56795916
23Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.56704516
24Propanoate metabolism_Homo sapiens_hsa006401.51424031
25Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.50985313
26Pyruvate metabolism_Homo sapiens_hsa006201.41516912
27Pentose and glucuronate interconversions_Homo sapiens_hsa000401.38399819
28Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.38099733
29One carbon pool by folate_Homo sapiens_hsa006701.37629394
30RNA transport_Homo sapiens_hsa030131.35967729
31Tight junction_Homo sapiens_hsa045301.35129178
32Glycolysis / Gluconeogenesis_Homo sapiens_hsa000101.32707394
33Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.32693024
34Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.29859048
35Wnt signaling pathway_Homo sapiens_hsa043101.29564822
36Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.22867275
37Butanoate metabolism_Homo sapiens_hsa006501.21064687
38Chronic myeloid leukemia_Homo sapiens_hsa052201.20827152
39Hedgehog signaling pathway_Homo sapiens_hsa043401.20665476
40ErbB signaling pathway_Homo sapiens_hsa040121.20195011
41Arginine biosynthesis_Homo sapiens_hsa002201.19177986
42Fatty acid metabolism_Homo sapiens_hsa012121.18513017
43Central carbon metabolism in cancer_Homo sapiens_hsa052301.16137321
44PPAR signaling pathway_Homo sapiens_hsa033201.15843215
45Choline metabolism in cancer_Homo sapiens_hsa052311.13373487
46Renal cell carcinoma_Homo sapiens_hsa052111.12879237
47Glioma_Homo sapiens_hsa052141.12162838
48Cysteine and methionine metabolism_Homo sapiens_hsa002701.11362429
49Longevity regulating pathway - multiple species_Homo sapiens_hsa042131.10262673
50ECM-receptor interaction_Homo sapiens_hsa045121.09415112
51Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.08961973
52Drug metabolism - other enzymes_Homo sapiens_hsa009831.08706408
53Melanogenesis_Homo sapiens_hsa049161.08265424
54Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.07138609
55Vitamin B6 metabolism_Homo sapiens_hsa007501.06904793
56N-Glycan biosynthesis_Homo sapiens_hsa005101.05739665
57Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.05619169
58Base excision repair_Homo sapiens_hsa034101.04969798
59Hippo signaling pathway_Homo sapiens_hsa043901.00847113
60Acute myeloid leukemia_Homo sapiens_hsa052210.99558698
61Insulin signaling pathway_Homo sapiens_hsa049100.99287020
62VEGF signaling pathway_Homo sapiens_hsa043700.97363037
63Longevity regulating pathway - mammal_Homo sapiens_hsa042110.97279943
64Nucleotide excision repair_Homo sapiens_hsa034200.95580734
65Cell cycle_Homo sapiens_hsa041100.94323770
66MicroRNAs in cancer_Homo sapiens_hsa052060.93973227
67Neurotrophin signaling pathway_Homo sapiens_hsa047220.93247485
68Non-homologous end-joining_Homo sapiens_hsa034500.91446617
69Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.91421497
70Bile secretion_Homo sapiens_hsa049760.90964094
71Peroxisome_Homo sapiens_hsa041460.90152826
72Dorso-ventral axis formation_Homo sapiens_hsa043200.89869076
73Melanoma_Homo sapiens_hsa052180.89825745
74Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.88793066
75Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.88407146
76Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.88311727
77mRNA surveillance pathway_Homo sapiens_hsa030150.88183563
78DNA replication_Homo sapiens_hsa030300.87258614
79beta-Alanine metabolism_Homo sapiens_hsa004100.86944600
80AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.85376253
81Estrogen signaling pathway_Homo sapiens_hsa049150.83850039
82Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.81346974
83Phenylalanine metabolism_Homo sapiens_hsa003600.81137850
84Small cell lung cancer_Homo sapiens_hsa052220.80008311
85Spliceosome_Homo sapiens_hsa030400.79545359
86Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.79269523
87Antigen processing and presentation_Homo sapiens_hsa046120.78988298
88Axon guidance_Homo sapiens_hsa043600.78406469
89HTLV-I infection_Homo sapiens_hsa051660.78221935
90Glycosaminoglycan degradation_Homo sapiens_hsa005310.76758851
91Folate biosynthesis_Homo sapiens_hsa007900.76581348
92Tyrosine metabolism_Homo sapiens_hsa003500.76462050
93p53 signaling pathway_Homo sapiens_hsa041150.75541168
94TGF-beta signaling pathway_Homo sapiens_hsa043500.75516806
95Insulin resistance_Homo sapiens_hsa049310.74352865
96Sulfur metabolism_Homo sapiens_hsa009200.73893391
97Gap junction_Homo sapiens_hsa045400.73287300
98Adherens junction_Homo sapiens_hsa045200.73221890
99Oocyte meiosis_Homo sapiens_hsa041140.71254307
100Inositol phosphate metabolism_Homo sapiens_hsa005620.71162865
101Complement and coagulation cascades_Homo sapiens_hsa046100.71093859
102Viral carcinogenesis_Homo sapiens_hsa052030.71034992
103mTOR signaling pathway_Homo sapiens_hsa041500.69888436
104Proteoglycans in cancer_Homo sapiens_hsa052050.68194877
105Amoebiasis_Homo sapiens_hsa051460.68109518
106Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.67432613
107Regulation of actin cytoskeleton_Homo sapiens_hsa048100.67296624
108Vitamin digestion and absorption_Homo sapiens_hsa049770.65596316
109Fructose and mannose metabolism_Homo sapiens_hsa000510.65183372
110Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.64886912
111Thyroid hormone synthesis_Homo sapiens_hsa049180.64737558
112Leukocyte transendothelial migration_Homo sapiens_hsa046700.63917784
113Sphingolipid signaling pathway_Homo sapiens_hsa040710.63514102
114Prolactin signaling pathway_Homo sapiens_hsa049170.63148626
115Pancreatic cancer_Homo sapiens_hsa052120.62086112
116AMPK signaling pathway_Homo sapiens_hsa041520.60666927
117Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.60580820
118Glycerolipid metabolism_Homo sapiens_hsa005610.60253421
119Thyroid hormone signaling pathway_Homo sapiens_hsa049190.59540947
120Histidine metabolism_Homo sapiens_hsa003400.59472265
121Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.59295786
122Glutathione metabolism_Homo sapiens_hsa004800.58903804
123Phosphatidylinositol signaling system_Homo sapiens_hsa040700.58803177
124Arginine and proline metabolism_Homo sapiens_hsa003300.56860212
125Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.56569823
126PI3K-Akt signaling pathway_Homo sapiens_hsa041510.56425433
127Glucagon signaling pathway_Homo sapiens_hsa049220.55579291
128Fat digestion and absorption_Homo sapiens_hsa049750.55462899
129Phospholipase D signaling pathway_Homo sapiens_hsa040720.54507661
130Colorectal cancer_Homo sapiens_hsa052100.54460626
131FoxO signaling pathway_Homo sapiens_hsa040680.53480383
132Apoptosis_Homo sapiens_hsa042100.52704603
133Protein digestion and absorption_Homo sapiens_hsa049740.51455999
134Starch and sucrose metabolism_Homo sapiens_hsa005000.51194116
135Carbohydrate digestion and absorption_Homo sapiens_hsa049730.50497529
136Sphingolipid metabolism_Homo sapiens_hsa006000.50415035
137Mismatch repair_Homo sapiens_hsa034300.49544947
138Hepatitis C_Homo sapiens_hsa051600.48920537
139Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.48187038
140Prion diseases_Homo sapiens_hsa050200.47958413
141Systemic lupus erythematosus_Homo sapiens_hsa053220.47077374
142Viral myocarditis_Homo sapiens_hsa054160.44948133
143T cell receptor signaling pathway_Homo sapiens_hsa046600.43481797
144Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.42985819
145Non-small cell lung cancer_Homo sapiens_hsa052230.38367358
146Pathways in cancer_Homo sapiens_hsa052000.38163898
147Focal adhesion_Homo sapiens_hsa045100.37945726
148Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.37854003
149Primary immunodeficiency_Homo sapiens_hsa053400.37756067
150Chemical carcinogenesis_Homo sapiens_hsa052040.36149464

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