Rank | Gene Set | Z-score |
---|---|---|
1 | neuron cell-cell adhesion (GO:0007158) | 6.09757047 |
2 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act | 5.95243822 |
3 | regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310) | 5.75941572 |
4 | vocalization behavior (GO:0071625) | 5.71001366 |
5 | regulation of short-term neuronal synaptic plasticity (GO:0048172) | 5.67399723 |
6 | regulation of glutamate receptor signaling pathway (GO:1900449) | 5.49755917 |
7 | presynaptic membrane assembly (GO:0097105) | 5.43857296 |
8 | positive regulation of excitatory postsynaptic membrane potential (GO:2000463) | 5.42999769 |
9 | synaptic vesicle docking involved in exocytosis (GO:0016081) | 5.30299993 |
10 | protein localization to synapse (GO:0035418) | 5.27740828 |
11 | synaptic vesicle exocytosis (GO:0016079) | 5.23153463 |
12 | postsynaptic membrane organization (GO:0001941) | 5.08875604 |
13 | neurotransmitter-gated ion channel clustering (GO:0072578) | 5.06406102 |
14 | glutamate secretion (GO:0014047) | 5.05146320 |
15 | regulation of synaptic vesicle exocytosis (GO:2000300) | 4.99026191 |
16 | presynaptic membrane organization (GO:0097090) | 4.87793195 |
17 | pyrimidine nucleobase catabolic process (GO:0006208) | 4.71657122 |
18 | ionotropic glutamate receptor signaling pathway (GO:0035235) | 4.59614791 |
19 | locomotory exploration behavior (GO:0035641) | 4.56708427 |
20 | synaptic vesicle maturation (GO:0016188) | 4.56653656 |
21 | positive regulation of calcium ion-dependent exocytosis (GO:0045956) | 4.54304608 |
22 | negative regulation of synaptic transmission, GABAergic (GO:0032229) | 4.48027239 |
23 | regulation of synaptic vesicle transport (GO:1902803) | 4.34890812 |
24 | neurotransmitter secretion (GO:0007269) | 4.29991240 |
25 | glutamate receptor signaling pathway (GO:0007215) | 4.29086043 |
26 | neuron recognition (GO:0008038) | 4.24703871 |
27 | synaptic transmission, glutamatergic (GO:0035249) | 4.18843669 |
28 | neuron-neuron synaptic transmission (GO:0007270) | 4.13479900 |
29 | regulation of inhibitory postsynaptic membrane potential (GO:0060080) | 4.10148627 |
30 | gamma-aminobutyric acid signaling pathway (GO:0007214) | 4.04014828 |
31 | exploration behavior (GO:0035640) | 3.97814914 |
32 | regulation of gene silencing by RNA (GO:0060966) | 3.95414924 |
33 | regulation of posttranscriptional gene silencing (GO:0060147) | 3.95414924 |
34 | regulation of gene silencing by miRNA (GO:0060964) | 3.95414924 |
35 | positive regulation of synaptic transmission, GABAergic (GO:0032230) | 3.94316875 |
36 | startle response (GO:0001964) | 3.91913765 |
37 | regulation of respiratory gaseous exchange by neurological system process (GO:0002087) | 3.90837149 |
38 | axonal fasciculation (GO:0007413) | 3.90553724 |
39 | response to histamine (GO:0034776) | 3.86746254 |
40 | cerebellar granule cell differentiation (GO:0021707) | 3.82654731 |
41 | neuronal action potential propagation (GO:0019227) | 3.82383059 |
42 | nucleobase catabolic process (GO:0046113) | 3.82134855 |
43 | regulation of postsynaptic membrane potential (GO:0060078) | 3.77031906 |
44 | regulation of excitatory postsynaptic membrane potential (GO:0060079) | 3.74544743 |
45 | positive regulation of synapse assembly (GO:0051965) | 3.70372011 |
46 | dendritic spine morphogenesis (GO:0060997) | 3.69038740 |
47 | gamma-aminobutyric acid transport (GO:0015812) | 3.68676423 |
48 | positive regulation of membrane potential (GO:0045838) | 3.66321299 |
49 | positive regulation of neurotransmitter secretion (GO:0001956) | 3.64406305 |
50 | proline transport (GO:0015824) | 3.62992579 |
51 | regulation of long-term neuronal synaptic plasticity (GO:0048169) | 3.62207650 |
52 | layer formation in cerebral cortex (GO:0021819) | 3.59831962 |
53 | neurotransmitter transport (GO:0006836) | 3.58701887 |
54 | positive regulation of dendritic spine morphogenesis (GO:0061003) | 3.56607950 |
55 | G-protein coupled glutamate receptor signaling pathway (GO:0007216) | 3.54281852 |
56 | regulation of synaptic transmission, glutamatergic (GO:0051966) | 3.54159617 |
57 | regulation of neuronal synaptic plasticity (GO:0048168) | 3.51274082 |
58 | regulation of neurotransmitter secretion (GO:0046928) | 3.50104890 |
59 | auditory behavior (GO:0031223) | 3.48628489 |
60 | positive regulation of synaptic transmission, glutamatergic (GO:0051968) | 3.48389792 |
61 | positive regulation of synapse maturation (GO:0090129) | 3.44029195 |
62 | regulation of respiratory system process (GO:0044065) | 3.43964171 |
63 | response to auditory stimulus (GO:0010996) | 3.42892538 |
64 | cerebellar Purkinje cell differentiation (GO:0021702) | 3.41706948 |
65 | synapse assembly (GO:0007416) | 3.39189182 |
66 | long-term memory (GO:0007616) | 3.37611268 |
67 | regulation of synapse assembly (GO:0051963) | 3.33343667 |
68 | transmission of nerve impulse (GO:0019226) | 3.31433468 |
69 | positive regulation of neurotransmitter transport (GO:0051590) | 3.31026948 |
70 | kidney morphogenesis (GO:0060993) | 3.28374115 |
71 | atrial cardiac muscle cell action potential (GO:0086014) | 3.28209122 |
72 | mechanosensory behavior (GO:0007638) | 3.27777135 |
73 | negative regulation of translation involved in gene silencing by miRNA (GO:0035278) | 3.27163694 |
74 | negative regulation of translation, ncRNA-mediated (GO:0040033) | 3.27163694 |
75 | regulation of translation, ncRNA-mediated (GO:0045974) | 3.27163694 |
76 | regulation of neurotransmitter levels (GO:0001505) | 3.27110695 |
77 | long-term synaptic potentiation (GO:0060291) | 3.24234861 |
78 | membrane hyperpolarization (GO:0060081) | 3.23059444 |
79 | regulation of synaptic transmission, GABAergic (GO:0032228) | 3.20602179 |
80 | regulation of neurotransmitter transport (GO:0051588) | 3.20306743 |
81 | membrane depolarization during cardiac muscle cell action potential (GO:0086012) | 3.15175126 |
82 | regulation of vesicle fusion (GO:0031338) | 3.14628028 |
83 | regulation of synapse structural plasticity (GO:0051823) | 3.10902953 |
84 | pre-miRNA processing (GO:0031054) | 3.10068904 |
85 | regulation of synapse maturation (GO:0090128) | 3.10025801 |
86 | righting reflex (GO:0060013) | 3.08444469 |
87 | membrane depolarization (GO:0051899) | 3.08219772 |
88 | negative regulation of synaptic transmission, glutamatergic (GO:0051967) | 3.07308175 |
89 | regulation of telomere maintenance via telomerase (GO:0032210) | 3.07146459 |
90 | regulation of dendritic spine morphogenesis (GO:0061001) | 3.06861593 |
91 | regulation of synaptic plasticity (GO:0048167) | 3.06672748 |
92 | cerebral cortex radially oriented cell migration (GO:0021799) | 3.04977022 |
93 | short-term memory (GO:0007614) | 3.03792716 |
94 | regulation of respiratory gaseous exchange (GO:0043576) | 3.03069176 |
95 | synaptic vesicle endocytosis (GO:0048488) | 3.02906759 |
96 | negative regulation of DNA-dependent DNA replication (GO:2000104) | 3.02237812 |
97 | positive regulation of synaptic transmission (GO:0050806) | 2.98576275 |
98 | opioid receptor signaling pathway (GO:0038003) | 2.97443047 |
99 | central nervous system projection neuron axonogenesis (GO:0021952) | 2.95999468 |
100 | regulation of dendritic spine development (GO:0060998) | 2.95606608 |
101 | synaptic transmission (GO:0007268) | 2.93602434 |
102 | social behavior (GO:0035176) | 2.92933114 |
103 | intraspecies interaction between organisms (GO:0051703) | 2.92933114 |
104 | learning (GO:0007612) | 2.92468122 |
105 | positive regulation of potassium ion transmembrane transporter activity (GO:1901018) | 2.91715409 |
106 | regulation of synapse organization (GO:0050807) | 2.91327615 |
107 | behavioral defense response (GO:0002209) | 2.90237601 |
108 | behavioral fear response (GO:0001662) | 2.90237601 |
109 | innervation (GO:0060384) | 2.87924367 |
110 | cochlea development (GO:0090102) | 2.86907243 |
111 | dendrite morphogenesis (GO:0048813) | 2.86115466 |
112 | dendrite development (GO:0016358) | 2.85482520 |
113 | synapse organization (GO:0050808) | 2.85050481 |
114 | negative regulation of dendrite morphogenesis (GO:0050774) | 2.84765797 |
115 | membrane depolarization during action potential (GO:0086010) | 2.84758941 |
116 | regulation of nuclear cell cycle DNA replication (GO:0033262) | 2.76983549 |
117 | regulation of mitotic spindle checkpoint (GO:1903504) | 2.73106965 |
118 | regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266) | 2.73106965 |
119 | regulation of feeding behavior (GO:0060259) | 2.72429698 |
120 | regulation of cell fate specification (GO:0042659) | 2.70955726 |
121 | regulation of mesoderm development (GO:2000380) | 2.70881946 |
122 | limb bud formation (GO:0060174) | 2.70166378 |
123 | establishment of integrated proviral latency (GO:0075713) | 2.65629899 |
124 | DNA double-strand break processing (GO:0000729) | 2.63714278 |
125 | negative regulation of dendrite development (GO:2000171) | 2.63431997 |
126 | regulation of telomere maintenance (GO:0032204) | 2.63037861 |
127 | regulation of Wnt signaling pathway, planar cell polarity pathway (GO:2000095) | 2.57445453 |
128 | dorsal/ventral axis specification (GO:0009950) | 2.51908106 |
129 | cell fate commitment involved in formation of primary germ layer (GO:0060795) | 2.48584757 |
130 | chromatin remodeling at centromere (GO:0031055) | 2.48394124 |
131 | inner ear receptor cell development (GO:0060119) | 2.46602189 |
132 | fear response (GO:0042596) | 2.43486134 |
133 | regulation of growth hormone secretion (GO:0060123) | 2.42979942 |
134 | negative regulation of catecholamine secretion (GO:0033604) | 2.42480278 |
135 | serotonin receptor signaling pathway (GO:0007210) | 2.39620017 |
136 | replication fork processing (GO:0031297) | 2.38972502 |
137 | histone exchange (GO:0043486) | 2.38677131 |
138 | lung-associated mesenchyme development (GO:0060484) | 2.35564570 |
139 | negative regulation of DNA recombination (GO:0045910) | 2.34819114 |
140 | regulation of centriole replication (GO:0046599) | 2.32452621 |
141 | CENP-A containing nucleosome assembly (GO:0034080) | 2.32147238 |
142 | olfactory bulb development (GO:0021772) | 2.31556984 |
143 | positive regulation of growth hormone secretion (GO:0060124) | 2.30590209 |
144 | otic vesicle formation (GO:0030916) | 2.29554839 |
145 | C4-dicarboxylate transport (GO:0015740) | 2.29260824 |
146 | paraxial mesoderm development (GO:0048339) | 2.28518494 |
147 | cell migration in hindbrain (GO:0021535) | 2.27574699 |
148 | regulation of helicase activity (GO:0051095) | 2.26681272 |
149 | mitotic sister chromatid cohesion (GO:0007064) | 2.25988832 |
150 | regulation of hexokinase activity (GO:1903299) | 2.24874212 |
151 | regulation of glucokinase activity (GO:0033131) | 2.24874212 |
152 | DNA replication-dependent nucleosome assembly (GO:0006335) | 2.22857976 |
153 | DNA replication-dependent nucleosome organization (GO:0034723) | 2.22857976 |
154 | chemosensory behavior (GO:0007635) | 2.21133854 |
155 | regulation of non-canonical Wnt signaling pathway (GO:2000050) | 2.21007370 |
156 | maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005) | 2.19386355 |
157 | regulation of cell fate commitment (GO:0010453) | 2.18467638 |
158 | single strand break repair (GO:0000012) | 2.17401133 |
159 | L-serine metabolic process (GO:0006563) | 2.17324384 |
160 | cAMP-mediated signaling (GO:0019933) | 2.15341911 |
161 | DNA replication checkpoint (GO:0000076) | 2.14960685 |
162 | DNA damage response, detection of DNA damage (GO:0042769) | 2.14918015 |
Rank | Gene Set | Z-score |
---|---|---|
1 | EZH2_22144423_ChIP-Seq_EOC_Human | 5.72109894 |
2 | GBX2_23144817_ChIP-Seq_PC3_Human | 4.49584924 |
3 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 3.02662978 |
4 | * SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 2.96287729 |
5 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 2.93082490 |
6 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 2.83337648 |
7 | * SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 2.78740879 |
8 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 2.59909232 |
9 | TAF15_26573619_Chip-Seq_HEK293_Human | 2.51838819 |
10 | * REST_21632747_ChIP-Seq_MESCs_Mouse | 2.48173518 |
11 | * SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 2.46934805 |
12 | * GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 2.46847451 |
13 | * SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 2.42689853 |
14 | * EZH2_18974828_ChIP-Seq_MESCs_Mouse | 2.41311665 |
15 | * RNF2_18974828_ChIP-Seq_MESCs_Mouse | 2.41311665 |
16 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 2.37873460 |
17 | * CTBP2_25329375_ChIP-Seq_LNCAP_Human | 2.35252995 |
18 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.35194936 |
19 | * EED_16625203_ChIP-ChIP_MESCs_Mouse | 2.34371037 |
20 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 2.31093309 |
21 | * ZFP57_27257070_Chip-Seq_ESCs_Mouse | 2.22915957 |
22 | * MTF2_20144788_ChIP-Seq_MESCs_Mouse | 2.16561918 |
23 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 2.15866159 |
24 | * SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 2.15145160 |
25 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 2.12551088 |
26 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 2.03660752 |
27 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 2.03102025 |
28 | DROSHA_22980978_ChIP-Seq_HELA_Human | 2.03028289 |
29 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 2.02993341 |
30 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 2.01501949 |
31 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 2.01419461 |
32 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.99660321 |
33 | * CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.99420526 |
34 | * SUZ12_27294783_Chip-Seq_ESCs_Mouse | 1.97729922 |
35 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.95121412 |
36 | * P300_19829295_ChIP-Seq_ESCs_Human | 1.89993814 |
37 | * SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.89441421 |
38 | * SMAD4_21799915_ChIP-Seq_A2780_Human | 1.86795098 |
39 | * REST_18959480_ChIP-ChIP_MESCs_Mouse | 1.85559040 |
40 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.85162422 |
41 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.85024161 |
42 | * PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.74981413 |
43 | * POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.74066815 |
44 | * RARB_27405468_Chip-Seq_BRAIN_Mouse | 1.73062109 |
45 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.68469250 |
46 | FUS_26573619_Chip-Seq_HEK293_Human | 1.67664065 |
47 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.66971995 |
48 | E2F7_22180533_ChIP-Seq_HELA_Human | 1.64326359 |
49 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.63689293 |
50 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.57156546 |
51 | * SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.56857335 |
52 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 1.56693903 |
53 | * PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.49572596 |
54 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.49539148 |
55 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 1.48384171 |
56 | * SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.47881973 |
57 | * RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.45393367 |
58 | * PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 1.45222326 |
59 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.45166751 |
60 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.45112416 |
61 | VDR_22108803_ChIP-Seq_LS180_Human | 1.45069930 |
62 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.44346966 |
63 | * AR_25329375_ChIP-Seq_VCAP_Human | 1.39627301 |
64 | * STAT3_23295773_ChIP-Seq_U87_Human | 1.36879671 |
65 | * SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.36767881 |
66 | SOX2_21211035_ChIP-Seq_LN229_Gbm | 1.34901730 |
67 | NANOG_18700969_ChIP-ChIP_MESCs_Mouse | 1.34393511 |
68 | KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 1.33005804 |
69 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.31182411 |
70 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.31182411 |
71 | * NANOG_16153702_ChIP-ChIP_HESCs_Human | 1.30260805 |
72 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.29851978 |
73 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.27884283 |
74 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 1.26632821 |
75 | GATA1_26923725_Chip-Seq_HPCs_Mouse | 1.25827983 |
76 | * AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.25369010 |
77 | * TCF4_23295773_ChIP-Seq_U87_Human | 1.25104458 |
78 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.23454369 |
79 | * TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.23141914 |
80 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.23091924 |
81 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 1.22804997 |
82 | * UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.22610263 |
83 | * CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.22534709 |
84 | HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse | 1.21357603 |
85 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 1.20573450 |
86 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 1.18897554 |
87 | KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse | 1.18327589 |
88 | TBX3_20139965_ChIP-Seq_ESCs_Mouse | 1.18299969 |
89 | TBX3_20139965_ChIP-Seq_MESCs_Mouse | 1.18211646 |
90 | * RUNX2_22187159_ChIP-Seq_PCA_Human | 1.17853109 |
91 | SALL4_18804426_ChIP-ChIP_MESCs_Mouse | 1.17634834 |
92 | STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse | 1.16998262 |
93 | RING1B_27294783_Chip-Seq_ESCs_Mouse | 1.15220276 |
94 | RCOR2_21632747_ChIP-Seq_MESCs_Mouse | 1.15146208 |
95 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.14626814 |
96 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.14626814 |
97 | POU5F1_18347094_ChIP-ChIP_MESCs_Mouse | 1.14363922 |
98 | JUN_21703547_ChIP-Seq_K562_Human | 1.14061009 |
99 | P53_22127205_ChIP-Seq_FIBROBLAST_Human | 1.13409432 |
100 | EWS_26573619_Chip-Seq_HEK293_Human | 1.13291625 |
101 | NR3C1_23031785_ChIP-Seq_PC12_Mouse | 1.13285250 |
102 | AR_19668381_ChIP-Seq_PC3_Human | 1.12485429 |
103 | * MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.11908753 |
104 | TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse | 1.11683292 |
105 | E2F1_18555785_Chip-Seq_ESCs_Mouse | 1.11506275 |
106 | * KLF5_20875108_ChIP-Seq_MESCs_Mouse | 1.11074435 |
107 | * TRIM28_17542650_ChIP-ChIP_NTERA2_Human | 1.10616654 |
108 | AHR_22903824_ChIP-Seq_MCF-7_Human | 1.10600924 |
109 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 1.10365361 |
110 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 1.09740243 |
111 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 1.09460554 |
112 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.08613625 |
113 | YAP1_20516196_ChIP-Seq_MESCs_Mouse | 1.08341759 |
114 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.07779593 |
115 | * LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.07314509 |
116 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 1.07207863 |
117 | * TP53_18474530_ChIP-ChIP_U2OS_Human | 1.06349625 |
118 | ZNF217_24962896_ChIP-Seq_MCF-7_Human | 1.06340386 |
119 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.05559870 |
120 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.05451763 |
121 | RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse | 1.05353131 |
122 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 1.05076807 |
123 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.04918352 |
124 | * SMAD3_21741376_ChIP-Seq_ESCs_Human | 1.04158737 |
125 | P53_22387025_ChIP-Seq_ESCs_Mouse | 1.02938525 |
126 | * GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.02827818 |
127 | * MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse | 1.02133328 |
128 | CMYC_18555785_Chip-Seq_ESCs_Mouse | 1.01694752 |
129 | * TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.00936326 |
130 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.00008944 |
131 | CEBPB_26923725_Chip-Seq_MESODERM_Mouse | 0.99152410 |
132 | * KDM2B_26808549_Chip-Seq_REH_Human | 0.99099943 |
133 | TCF4_22108803_ChIP-Seq_LS180_Human | 0.98590238 |
134 | RING1B_27294783_Chip-Seq_NPCs_Mouse | 0.97877248 |
135 | SOX2_19829295_ChIP-Seq_ESCs_Human | 0.96626599 |
136 | NANOG_19829295_ChIP-Seq_ESCs_Human | 0.96626599 |
137 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 0.95706335 |
138 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 0.95333675 |
139 | SOX9_26525672_Chip-Seq_HEART_Mouse | 0.94826041 |
140 | SUZ12_18555785_Chip-Seq_ESCs_Mouse | 0.94463238 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0003880_abnormal_central_pattern | 5.53779429 |
2 | MP0004859_abnormal_synaptic_plasticity | 4.95152304 |
3 | MP0003635_abnormal_synaptic_transmissio | 3.68978553 |
4 | MP0001968_abnormal_touch/_nociception | 3.53592598 |
5 | MP0003890_abnormal_embryonic-extraembry | 3.26156771 |
6 | MP0009745_abnormal_behavioral_response | 3.26040146 |
7 | MP0009046_muscle_twitch | 3.21714517 |
8 | MP0002064_seizures | 2.97428845 |
9 | MP0004270_analgesia | 2.97387483 |
10 | MP0002063_abnormal_learning/memory/cond | 2.97217780 |
11 | MP0005423_abnormal_somatic_nervous | 2.87834098 |
12 | MP0002736_abnormal_nociception_after | 2.83782583 |
13 | MP0002572_abnormal_emotion/affect_behav | 2.79625390 |
14 | MP0002734_abnormal_mechanical_nocicepti | 2.63226828 |
15 | MP0001486_abnormal_startle_reflex | 2.49900598 |
16 | MP0002735_abnormal_chemical_nociception | 2.49880406 |
17 | MP0006276_abnormal_autonomic_nervous | 2.48070472 |
18 | MP0005645_abnormal_hypothalamus_physiol | 2.43582635 |
19 | MP0002272_abnormal_nervous_system | 2.42905247 |
20 | MP0003122_maternal_imprinting | 2.39350568 |
21 | MP0001440_abnormal_grooming_behavior | 2.34697120 |
22 | MP0001501_abnormal_sleep_pattern | 2.29241603 |
23 | MP0005646_abnormal_pituitary_gland | 2.22976905 |
24 | MP0002067_abnormal_sensory_capabilities | 2.10357762 |
25 | MP0001188_hyperpigmentation | 2.06346176 |
26 | MP0003941_abnormal_skin_development | 1.99070595 |
27 | MP0003787_abnormal_imprinting | 1.98467163 |
28 | MP0003119_abnormal_digestive_system | 1.96492289 |
29 | MP0002254_reproductive_system_inflammat | 1.95929118 |
30 | MP0002184_abnormal_innervation | 1.92864008 |
31 | MP0002557_abnormal_social/conspecific_i | 1.92233308 |
32 | MP0000778_abnormal_nervous_system | 1.92036615 |
33 | MP0009780_abnormal_chondrocyte_physiolo | 1.90112516 |
34 | MP0004924_abnormal_behavior | 1.85271862 |
35 | MP0005386_behavior/neurological_phenoty | 1.85271862 |
36 | MP0001970_abnormal_pain_threshold | 1.82565635 |
37 | MP0002733_abnormal_thermal_nociception | 1.82291344 |
38 | MP0003879_abnormal_hair_cell | 1.80568002 |
39 | MP0001984_abnormal_olfaction | 1.73167009 |
40 | MP0001529_abnormal_vocalization | 1.72562293 |
41 | MP0003136_yellow_coat_color | 1.68296688 |
42 | MP0000566_synostosis | 1.67999972 |
43 | MP0001293_anophthalmia | 1.66369148 |
44 | MP0002938_white_spotting | 1.63666736 |
45 | MP0003937_abnormal_limbs/digits/tail_de | 1.63088627 |
46 | MP0004133_heterotaxia | 1.59382432 |
47 | MP0004142_abnormal_muscle_tone | 1.49567101 |
48 | MP0000516_abnormal_urinary_system | 1.46406758 |
49 | MP0005367_renal/urinary_system_phenotyp | 1.46406758 |
50 | MP0003567_abnormal_fetal_cardiomyocyte | 1.46383753 |
51 | MP0004858_abnormal_nervous_system | 1.45798274 |
52 | MP0001502_abnormal_circadian_rhythm | 1.44748115 |
53 | MP0004811_abnormal_neuron_physiology | 1.44132757 |
54 | MP0002233_abnormal_nose_morphology | 1.43229769 |
55 | MP0000537_abnormal_urethra_morphology | 1.42373312 |
56 | MP0008569_lethality_at_weaning | 1.40071600 |
57 | MP0000049_abnormal_middle_ear | 1.39773101 |
58 | MP0004742_abnormal_vestibular_system | 1.38969626 |
59 | MP0008058_abnormal_DNA_repair | 1.38403826 |
60 | MP0009672_abnormal_birth_weight | 1.37420276 |
61 | MP0000955_abnormal_spinal_cord | 1.35419286 |
62 | MP0002882_abnormal_neuron_morphology | 1.32049021 |
63 | MP0003121_genomic_imprinting | 1.31366388 |
64 | MP0002876_abnormal_thyroid_physiology | 1.29895677 |
65 | MP0002066_abnormal_motor_capabilities/c | 1.27555453 |
66 | MP0001299_abnormal_eye_distance/ | 1.25639583 |
67 | MP0001905_abnormal_dopamine_level | 1.22773249 |
68 | MP0005551_abnormal_eye_electrophysiolog | 1.18895217 |
69 | MP0000631_abnormal_neuroendocrine_gland | 1.14690703 |
70 | MP0003693_abnormal_embryo_hatching | 1.14464863 |
71 | MP0003718_maternal_effect | 1.10067623 |
72 | MP0005171_absent_coat_pigmentation | 1.08705329 |
73 | MP0010030_abnormal_orbit_morphology | 1.07971872 |
74 | MP0004885_abnormal_endolymph | 1.04710544 |
75 | MP0008789_abnormal_olfactory_epithelium | 1.04262158 |
76 | MP0004957_abnormal_blastocyst_morpholog | 1.03651819 |
77 | MP0001963_abnormal_hearing_physiology | 1.03134832 |
78 | MP0002697_abnormal_eye_size | 1.02018699 |
79 | MP0002152_abnormal_brain_morphology | 1.01553887 |
80 | MP0002822_catalepsy | 0.99868099 |
81 | MP0010386_abnormal_urinary_bladder | 0.97952873 |
82 | MP0009703_decreased_birth_body | 0.97760054 |
83 | MP0003938_abnormal_ear_development | 0.97641900 |
84 | MP0003123_paternal_imprinting | 0.97473664 |
85 | MP0003633_abnormal_nervous_system | 0.96118112 |
86 | MP0008932_abnormal_embryonic_tissue | 0.95165703 |
87 | MP0002084_abnormal_developmental_patter | 0.94734280 |
88 | MP0000579_abnormal_nail_morphology | 0.93557145 |
89 | MP0008872_abnormal_physiological_respon | 0.92974744 |
90 | MP0002234_abnormal_pharynx_morphology | 0.92606650 |
91 | MP0001286_abnormal_eye_development | 0.91746918 |
92 | MP0008004_abnormal_stomach_pH | 0.90004024 |
93 | MP0010352_gastrointestinal_tract_polyps | 0.88944651 |
94 | MP0003755_abnormal_palate_morphology | 0.86293165 |
95 | MP0005409_darkened_coat_color | 0.85607615 |
96 | MP0002638_abnormal_pupillary_reflex | 0.84376902 |
97 | MP0010094_abnormal_chromosome_stability | 0.84105927 |
98 | MP0002069_abnormal_eating/drinking_beha | 0.84076688 |
99 | MP0002102_abnormal_ear_morphology | 0.83926701 |
100 | MP0002752_abnormal_somatic_nervous | 0.83408529 |
101 | MP0002909_abnormal_adrenal_gland | 0.83016552 |
102 | MP0002229_neurodegeneration | 0.82994778 |
103 | MP0002090_abnormal_vision | 0.82306833 |
104 | MP0000026_abnormal_inner_ear | 0.82002795 |
105 | MP0006292_abnormal_olfactory_placode | 0.81661058 |
106 | MP0001177_atelectasis | 0.81597157 |
107 | MP0004085_abnormal_heartbeat | 0.81490942 |
108 | MP0003631_nervous_system_phenotype | 0.81489478 |
109 | MP0000569_abnormal_digit_pigmentation | 0.81067894 |
110 | MP0003329_amyloid_beta_deposits | 0.80885950 |
111 | MP0001986_abnormal_taste_sensitivity | 0.80221644 |
112 | MP0002085_abnormal_embryonic_tissue | 0.80022040 |
113 | MP0002111_abnormal_tail_morphology | 0.79661729 |
114 | MP0004145_abnormal_muscle_electrophysio | 0.79203040 |
115 | MP0001485_abnormal_pinna_reflex | 0.77814152 |
116 | MP0001664_abnormal_digestion | 0.76932183 |
117 | MP0004484_altered_response_of | 0.76554948 |
118 | MP0002653_abnormal_ependyma_morphology | 0.76082040 |
119 | MP0002081_perinatal_lethality | 0.74814980 |
120 | MP0003195_calcinosis | 0.74006067 |
121 | MP0003111_abnormal_nucleus_morphology | 0.73878949 |
122 | MP0000751_myopathy | 0.71872952 |
123 | MP0005394_taste/olfaction_phenotype | 0.71798893 |
124 | MP0005499_abnormal_olfactory_system | 0.71798893 |
125 | MP0003646_muscle_fatigue | 0.71639321 |
126 | MP0002751_abnormal_autonomic_nervous | 0.71263111 |
127 | MP0008877_abnormal_DNA_methylation | 0.71151996 |
128 | MP0001943_abnormal_respiration | 0.67162650 |
129 | MP0006072_abnormal_retinal_apoptosis | 0.66592048 |
130 | MP0005253_abnormal_eye_physiology | 0.65401400 |
131 | MP0005535_abnormal_body_temperature | 0.65146552 |
132 | MP0002837_dystrophic_cardiac_calcinosis | 0.64762159 |
133 | MP0002163_abnormal_gland_morphology | 0.63508491 |
134 | MP0003283_abnormal_digestive_organ | 0.63011189 |
135 | MP0008874_decreased_physiological_sensi | 0.62926025 |
136 | MP0004215_abnormal_myocardial_fiber | 0.62616786 |
137 | MP0003861_abnormal_nervous_system | 0.57374311 |
138 | MP0010770_preweaning_lethality | 0.56600717 |
139 | MP0002082_postnatal_lethality | 0.56600717 |
140 | MP0010769_abnormal_survival | 0.54293184 |
141 | MP0004233_abnormal_muscle_weight | 0.51902280 |
142 | MP0010768_mortality/aging | 0.51610957 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Focal motor seizures (HP:0011153) | 7.88931605 |
2 | Epileptic encephalopathy (HP:0200134) | 5.96390470 |
3 | Atonic seizures (HP:0010819) | 5.28328104 |
4 | Focal seizures (HP:0007359) | 5.26211038 |
5 | Febrile seizures (HP:0002373) | 5.20904913 |
6 | Hyperventilation (HP:0002883) | 5.12338050 |
7 | Broad-based gait (HP:0002136) | 4.48993004 |
8 | Absence seizures (HP:0002121) | 4.43623127 |
9 | Myokymia (HP:0002411) | 4.28532291 |
10 | Progressive cerebellar ataxia (HP:0002073) | 4.13877705 |
11 | Dialeptic seizures (HP:0011146) | 4.07364551 |
12 | Visual hallucinations (HP:0002367) | 4.05331234 |
13 | Generalized tonic-clonic seizures (HP:0002069) | 3.80436752 |
14 | Colon cancer (HP:0003003) | 3.72606372 |
15 | Hepatoblastoma (HP:0002884) | 3.42318225 |
16 | Protruding tongue (HP:0010808) | 3.41581727 |
17 | Drooling (HP:0002307) | 3.37630549 |
18 | Excessive salivation (HP:0003781) | 3.37630549 |
19 | Hypoglycemic seizures (HP:0002173) | 3.27444757 |
20 | Gaze-evoked nystagmus (HP:0000640) | 3.21225760 |
21 | Poor eye contact (HP:0000817) | 3.09224125 |
22 | Septo-optic dysplasia (HP:0100842) | 3.02653625 |
23 | Fetal akinesia sequence (HP:0001989) | 3.00156898 |
24 | Polyphagia (HP:0002591) | 2.99753035 |
25 | Hyperinsulinemic hypoglycemia (HP:0000825) | 2.96724566 |
26 | Aqueductal stenosis (HP:0002410) | 2.94624434 |
27 | Inability to walk (HP:0002540) | 2.92571500 |
28 | Neoplasm of the adrenal cortex (HP:0100641) | 2.89842842 |
29 | Abnormal hair whorl (HP:0010721) | 2.89541811 |
30 | Absent speech (HP:0001344) | 2.88683313 |
31 | Abnormal eating behavior (HP:0100738) | 2.86156280 |
32 | Blue irides (HP:0000635) | 2.84921752 |
33 | Absent/shortened dynein arms (HP:0200106) | 2.77290990 |
34 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 2.77290990 |
35 | Progressive inability to walk (HP:0002505) | 2.75936912 |
36 | Urinary bladder sphincter dysfunction (HP:0002839) | 2.70196060 |
37 | Epileptiform EEG discharges (HP:0011182) | 2.67419981 |
38 | Truncal ataxia (HP:0002078) | 2.66332578 |
39 | Gait imbalance (HP:0002141) | 2.65820781 |
40 | Impaired vibration sensation in the lower limbs (HP:0002166) | 2.58481627 |
41 | Impaired social interactions (HP:0000735) | 2.58133504 |
42 | Abnormal social behavior (HP:0012433) | 2.58133504 |
43 | Dysdiadochokinesis (HP:0002075) | 2.55557844 |
44 | Ependymoma (HP:0002888) | 2.54817542 |
45 | Hyperglycinemia (HP:0002154) | 2.53638456 |
46 | Limb dystonia (HP:0002451) | 2.50684331 |
47 | Genetic anticipation (HP:0003743) | 2.47605023 |
48 | Amblyopia (HP:0000646) | 2.47559071 |
49 | EEG with generalized epileptiform discharges (HP:0011198) | 2.47431433 |
50 | Abnormality of the pancreatic islet cells (HP:0006476) | 2.45170646 |
51 | Abnormality of endocrine pancreas physiology (HP:0012093) | 2.45170646 |
52 | Hyperthyroidism (HP:0000836) | 2.45100372 |
53 | Abnormal ciliary motility (HP:0012262) | 2.42610684 |
54 | Cortical dysplasia (HP:0002539) | 2.40269765 |
55 | Vitreoretinal degeneration (HP:0000655) | 2.39731155 |
56 | Astrocytoma (HP:0009592) | 2.38894738 |
57 | Abnormality of the astrocytes (HP:0100707) | 2.38894738 |
58 | Optic nerve hypoplasia (HP:0000609) | 2.37515120 |
59 | Intestinal atresia (HP:0011100) | 2.36914613 |
60 | Abnormality of the labia minora (HP:0012880) | 2.36094747 |
61 | Glioma (HP:0009733) | 2.34223284 |
62 | Volvulus (HP:0002580) | 2.32695822 |
63 | Mutism (HP:0002300) | 2.32189946 |
64 | Anxiety (HP:0000739) | 2.29845395 |
65 | Fair hair (HP:0002286) | 2.29201139 |
66 | Aplasia/Hypoplasia of the optic nerve (HP:0008058) | 2.28629729 |
67 | Bifid tongue (HP:0010297) | 2.27816077 |
68 | Abnormality of the corticospinal tract (HP:0002492) | 2.26199779 |
69 | Abnormality of salivation (HP:0100755) | 2.25885535 |
70 | Generalized hypopigmentation of hair (HP:0011358) | 2.24588977 |
71 | Hypsarrhythmia (HP:0002521) | 2.24198768 |
72 | Ankle clonus (HP:0011448) | 2.23547561 |
73 | Medial flaring of the eyebrow (HP:0010747) | 2.21303713 |
74 | Depression (HP:0000716) | 2.20523920 |
75 | Agitation (HP:0000713) | 2.19666873 |
76 | Failure to thrive in infancy (HP:0001531) | 2.19308523 |
77 | Action tremor (HP:0002345) | 2.18937911 |
78 | Cutaneous finger syndactyly (HP:0010554) | 2.16953295 |
79 | Congenital primary aphakia (HP:0007707) | 2.15821001 |
80 | Renal hypoplasia (HP:0000089) | 2.15758290 |
81 | Impaired smooth pursuit (HP:0007772) | 2.14163357 |
82 | Dysmetria (HP:0001310) | 2.13953024 |
83 | Nephrogenic diabetes insipidus (HP:0009806) | 2.12174814 |
84 | Abnormality of the metopic suture (HP:0005556) | 2.11647666 |
85 | Stereotypic behavior (HP:0000733) | 2.10761687 |
86 | Poor suck (HP:0002033) | 2.09510207 |
87 | Embryonal renal neoplasm (HP:0011794) | 2.09402265 |
88 | Pancreatic islet-cell hyperplasia (HP:0004510) | 2.08626250 |
89 | Cutaneous syndactyly (HP:0012725) | 2.08021811 |
90 | Specific learning disability (HP:0001328) | 2.07684251 |
91 | Abnormal respiratory epithelium morphology (HP:0012253) | 2.06665237 |
92 | Abnormal respiratory motile cilium morphology (HP:0005938) | 2.06665237 |
93 | Hemiparesis (HP:0001269) | 2.06467646 |
94 | Aplasia/Hypoplasia of the sternum (HP:0006714) | 2.03979483 |
95 | Abnormal respiratory motile cilium physiology (HP:0012261) | 2.03856544 |
96 | Akinesia (HP:0002304) | 2.03772907 |
97 | Generalized myoclonic seizures (HP:0002123) | 2.03414335 |
98 | Hypoglycemic coma (HP:0001325) | 2.02397181 |
99 | Pheochromocytoma (HP:0002666) | 2.02295619 |
100 | Neoplasm of the adrenal gland (HP:0100631) | 2.02196566 |
101 | Status epilepticus (HP:0002133) | 2.01502491 |
102 | Exotropia (HP:0000577) | 2.01307213 |
103 | Hypoventilation (HP:0002791) | 2.00869348 |
104 | Prominent metopic ridge (HP:0005487) | 2.00545813 |
105 | Papilledema (HP:0001085) | 2.00289286 |
106 | Breast carcinoma (HP:0003002) | 2.00125574 |
107 | Absent septum pellucidum (HP:0001331) | 1.99912583 |
108 | Sleep apnea (HP:0010535) | 1.99821668 |
109 | Gastroesophageal reflux (HP:0002020) | 1.99431074 |
110 | Abnormal lung lobation (HP:0002101) | 1.99424340 |
111 | Inappropriate behavior (HP:0000719) | 1.99403813 |
112 | Narrow nasal bridge (HP:0000446) | 1.99232129 |
113 | Shoulder girdle muscle weakness (HP:0003547) | 1.99083692 |
114 | Widely spaced teeth (HP:0000687) | 1.98945251 |
115 | Urinary urgency (HP:0000012) | 1.98613620 |
116 | Nephroblastoma (Wilms tumor) (HP:0002667) | 1.98597282 |
117 | Scrotal hypoplasia (HP:0000046) | 1.98431885 |
118 | Abnormality of the septum pellucidum (HP:0007375) | 1.97589115 |
119 | Supranuclear gaze palsy (HP:0000605) | 1.97073738 |
120 | Postural instability (HP:0002172) | 1.93655823 |
121 | Absent eyebrow (HP:0002223) | 1.92648602 |
122 | Tubulointerstitial nephritis (HP:0001970) | 1.91948501 |
123 | Choanal stenosis (HP:0000452) | 1.91791896 |
124 | Symptomatic seizures (HP:0011145) | 1.91738713 |
125 | Insidious onset (HP:0003587) | 1.90649116 |
126 | Termporal pattern (HP:0011008) | 1.90649116 |
127 | Spastic gait (HP:0002064) | 1.90446852 |
128 | Agnosia (HP:0010524) | 1.89213420 |
129 | Bilateral microphthalmos (HP:0007633) | 1.89031177 |
130 | Esotropia (HP:0000565) | 1.88329581 |
131 | Preaxial foot polydactyly (HP:0001841) | 1.87095596 |
132 | Stenosis of the external auditory canal (HP:0000402) | 1.85966458 |
133 | Broad foot (HP:0001769) | 1.84240503 |
134 | Labial hypoplasia (HP:0000066) | 1.83494821 |
135 | Abnormality of the hip-girdle musculature (HP:0001445) | 1.82990105 |
136 | Abnormality of the musculature of the pelvis (HP:0001469) | 1.82990105 |
137 | Abnormality of the ileum (HP:0001549) | 1.82262253 |
138 | Methylmalonic acidemia (HP:0002912) | 1.81439890 |
139 | Scanning speech (HP:0002168) | 1.80875408 |
140 | Meckel diverticulum (HP:0002245) | 1.80205486 |
141 | Neuroendocrine neoplasm (HP:0100634) | 1.80090362 |
142 | Rhabdomyosarcoma (HP:0002859) | 1.80010104 |
143 | Open mouth (HP:0000194) | 1.79535692 |
144 | Abnormality of binocular vision (HP:0011514) | 1.79450508 |
145 | Diplopia (HP:0000651) | 1.79450508 |
146 | Abnormality of ocular smooth pursuit (HP:0000617) | 1.77958736 |
147 | Gastrointestinal atresia (HP:0002589) | 1.77937459 |
148 | Bradykinesia (HP:0002067) | 1.76134297 |
149 | Myelomeningocele (HP:0002475) | 1.75860323 |
150 | Pendular nystagmus (HP:0012043) | 1.75822422 |
151 | Atrophy/Degeneration involving the corticospinal tracts (HP:0007372) | 1.75647027 |
152 | Degeneration of the lateral corticospinal tracts (HP:0002314) | 1.75647027 |
153 | Lower limb muscle weakness (HP:0007340) | 1.75355288 |
154 | Genital tract atresia (HP:0001827) | 1.75034533 |
155 | Medulloblastoma (HP:0002885) | 1.73798246 |
156 | Vaginal atresia (HP:0000148) | 1.72660525 |
157 | Hypoplastic female external genitalia (HP:0012815) | 1.72295761 |
158 | Incomplete penetrance (HP:0003829) | 1.72257652 |
159 | Papillary thyroid carcinoma (HP:0002895) | 1.70189009 |
160 | Neoplasm of the oral cavity (HP:0100649) | 1.69412896 |
161 | Restlessness (HP:0000711) | 1.68532900 |
162 | Supernumerary spleens (HP:0009799) | 1.68429818 |
163 | Abnormality of serum amino acid levels (HP:0003112) | 1.67682547 |
164 | Anophthalmia (HP:0000528) | 1.66406261 |
165 | Pancreatic fibrosis (HP:0100732) | 1.64615212 |
166 | Enlarged penis (HP:0000040) | 1.63545596 |
167 | Abdominal situs inversus (HP:0003363) | 1.63406072 |
168 | Abnormality of abdominal situs (HP:0011620) | 1.63406072 |
169 | Thyroid carcinoma (HP:0002890) | 1.63089913 |
170 | Micropenis (HP:0000054) | 1.62294990 |
Rank | Gene Set | Z-score |
---|---|---|
1 | TRIM28 | 5.95749684 |
2 | CASK | 5.53054118 |
3 | NTRK3 | 4.12854249 |
4 | FRK | 3.66175710 |
5 | MARK1 | 3.59837195 |
6 | EPHA4 | 3.48353007 |
7 | MAP3K4 | 3.25963685 |
8 | MAP2K7 | 3.25159030 |
9 | FGFR2 | 2.90772729 |
10 | MAP3K12 | 2.73192154 |
11 | MAP3K9 | 2.62762340 |
12 | DAPK2 | 2.52567933 |
13 | MKNK2 | 2.18133789 |
14 | NTRK2 | 2.17320253 |
15 | TNIK | 2.12662283 |
16 | SIK2 | 2.08338082 |
17 | CCNB1 | 2.06699582 |
18 | MINK1 | 2.02825138 |
19 | MAP2K4 | 1.92416628 |
20 | STK38L | 1.91159614 |
21 | AKT3 | 1.89213277 |
22 | ZAK | 1.87963340 |
23 | MAPK13 | 1.85082822 |
24 | PLK2 | 1.78707989 |
25 | CDC7 | 1.77070391 |
26 | PLK3 | 1.68014307 |
27 | PRPF4B | 1.66591887 |
28 | CDK19 | 1.63779823 |
29 | MKNK1 | 1.62688212 |
30 | ACVR1B | 1.61771844 |
31 | SIK3 | 1.60812216 |
32 | PNCK | 1.59589467 |
33 | DAPK1 | 1.57003218 |
34 | PAK6 | 1.52558823 |
35 | SRPK1 | 1.50803533 |
36 | KSR1 | 1.42075895 |
37 | TTK | 1.39811025 |
38 | MAP4K2 | 1.30802009 |
39 | CDK5 | 1.25125183 |
40 | SGK2 | 1.22190473 |
41 | NUAK1 | 1.17153389 |
42 | PRKCG | 1.15635317 |
43 | CAMK2A | 1.13824248 |
44 | CSNK1G1 | 1.13735667 |
45 | SGK223 | 1.06004965 |
46 | SGK494 | 1.06004965 |
47 | GRK7 | 1.02306810 |
48 | CAMKK1 | 1.01184628 |
49 | TAF1 | 1.00091347 |
50 | OXSR1 | 0.99258127 |
51 | CAMKK2 | 0.97588770 |
52 | VRK1 | 0.93012624 |
53 | GRK5 | 0.92786508 |
54 | TNK2 | 0.91674586 |
55 | NLK | 0.90766126 |
56 | UHMK1 | 0.88190931 |
57 | CSNK1G2 | 0.85413467 |
58 | PLK4 | 0.85239379 |
59 | CAMK1 | 0.85133878 |
60 | NTRK1 | 0.83507149 |
61 | MAP3K10 | 0.82832481 |
62 | RIPK4 | 0.82313408 |
63 | PINK1 | 0.81710428 |
64 | WNK3 | 0.81222963 |
65 | LATS2 | 0.79216157 |
66 | FES | 0.78865064 |
67 | LATS1 | 0.77210728 |
68 | FGFR1 | 0.76711138 |
69 | PBK | 0.76349561 |
70 | BCR | 0.75218914 |
71 | PLK1 | 0.74518646 |
72 | SGK1 | 0.74022379 |
73 | CDK3 | 0.73988414 |
74 | PHKG2 | 0.73943592 |
75 | PHKG1 | 0.73943592 |
76 | PASK | 0.73904783 |
77 | SGK3 | 0.72754954 |
78 | KSR2 | 0.71503757 |
79 | BUB1 | 0.69888852 |
80 | ADRBK2 | 0.69798640 |
81 | RPS6KA4 | 0.68804268 |
82 | CDK18 | 0.68588574 |
83 | STK3 | 0.68337140 |
84 | PRKCE | 0.67309653 |
85 | TYRO3 | 0.66578236 |
86 | PAK3 | 0.66440333 |
87 | STK11 | 0.65220114 |
88 | CAMK2B | 0.64364514 |
89 | DYRK3 | 0.64141816 |
90 | CDK15 | 0.62690996 |
91 | CDK14 | 0.60448383 |
92 | STK38 | 0.58970716 |
93 | FLT3 | 0.58101653 |
94 | MAP3K6 | 0.58094796 |
95 | ERBB3 | 0.58009164 |
96 | BRSK2 | 0.57502183 |
97 | PRKCH | 0.56405401 |
98 | DYRK1A | 0.55099537 |
99 | ATM | 0.53758702 |
100 | CAMK1G | 0.53420777 |
101 | ALK | 0.53135280 |
102 | BMPR1B | 0.52522462 |
103 | MAPK12 | 0.52202894 |
104 | CAMK4 | 0.52009320 |
105 | CDK11A | 0.51943112 |
106 | INSRR | 0.51248477 |
107 | MAP3K2 | 0.50423231 |
108 | BRAF | 0.50232387 |
109 | NEK6 | 0.50100889 |
110 | MAPK7 | 0.49299592 |
111 | MARK2 | 0.49154477 |
112 | PRKD3 | 0.48106522 |
113 | ADRBK1 | 0.47382914 |
114 | RET | 0.47174519 |
115 | TIE1 | 0.46956391 |
116 | BMPR2 | 0.46524572 |
117 | CSNK1G3 | 0.46494487 |
118 | TGFBR1 | 0.45925822 |
119 | FGR | 0.45338547 |
120 | PKN1 | 0.45157461 |
121 | CSNK1E | 0.44623496 |
122 | WEE1 | 0.41635399 |
123 | VRK2 | 0.41584063 |
124 | PRKCZ | 0.41378038 |
125 | ERBB4 | 0.41025777 |
126 | GRK1 | 0.40799024 |
127 | NME1 | 0.39478969 |
128 | ATR | 0.38628633 |
129 | CAMK2D | 0.38506563 |
130 | PRKG1 | 0.38307828 |
131 | CHEK2 | 0.37539756 |
132 | EPHA3 | 0.37517531 |
133 | EIF2AK2 | 0.37326425 |
134 | RPS6KA2 | 0.37198683 |
135 | YES1 | 0.36986829 |
136 | PRKDC | 0.36860352 |
137 | TSSK6 | 0.36587124 |
138 | PIK3CA | 0.36316069 |
139 | RPS6KA3 | 0.36092591 |
140 | CAMK1D | 0.35655300 |
141 | MUSK | 0.34544137 |
142 | DYRK2 | 0.33966817 |
143 | PRKACA | 0.33492433 |
144 | CSNK1A1L | 0.33460176 |
145 | ARAF | 0.33285861 |
146 | CAMK2G | 0.32612585 |
147 | DAPK3 | 0.29575944 |
148 | PRKCB | 0.29377366 |
149 | WNK1 | 0.29171272 |
150 | CDK8 | 0.28900951 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Nicotine addiction_Homo sapiens_hsa05033 | 4.66871315 |
2 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 3.65848524 |
3 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 3.00061341 |
4 | GABAergic synapse_Homo sapiens_hsa04727 | 2.94127473 |
5 | Morphine addiction_Homo sapiens_hsa05032 | 2.79568648 |
6 | Circadian entrainment_Homo sapiens_hsa04713 | 2.62341263 |
7 | Olfactory transduction_Homo sapiens_hsa04740 | 2.56622896 |
8 | Glutamatergic synapse_Homo sapiens_hsa04724 | 2.53300510 |
9 | Long-term potentiation_Homo sapiens_hsa04720 | 2.38741509 |
10 | Amphetamine addiction_Homo sapiens_hsa05031 | 2.31373933 |
11 | Protein export_Homo sapiens_hsa03060 | 2.26439349 |
12 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 2.12347981 |
13 | Taste transduction_Homo sapiens_hsa04742 | 2.09913217 |
14 | Dopaminergic synapse_Homo sapiens_hsa04728 | 2.08501958 |
15 | Serotonergic synapse_Homo sapiens_hsa04726 | 2.07059681 |
16 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 2.03798585 |
17 | Salivary secretion_Homo sapiens_hsa04970 | 2.00625309 |
18 | Insulin secretion_Homo sapiens_hsa04911 | 1.95496641 |
19 | Long-term depression_Homo sapiens_hsa04730 | 1.88147283 |
20 | Renin secretion_Homo sapiens_hsa04924 | 1.82280603 |
21 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.81686079 |
22 | Cholinergic synapse_Homo sapiens_hsa04725 | 1.75424718 |
23 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.72861539 |
24 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.67989743 |
25 | Cocaine addiction_Homo sapiens_hsa05030 | 1.66964364 |
26 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.66244479 |
27 | Calcium signaling pathway_Homo sapiens_hsa04020 | 1.61986343 |
28 | Gastric acid secretion_Homo sapiens_hsa04971 | 1.61184744 |
29 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 1.57106712 |
30 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 1.55441837 |
31 | Mismatch repair_Homo sapiens_hsa03430 | 1.53653594 |
32 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 1.51433012 |
33 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.50803516 |
34 | * Axon guidance_Homo sapiens_hsa04360 | 1.45103865 |
35 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 1.42786453 |
36 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 1.39730031 |
37 | Phototransduction_Homo sapiens_hsa04744 | 1.38938411 |
38 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.36480772 |
39 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.34925628 |
40 | Basal transcription factors_Homo sapiens_hsa03022 | 1.34268103 |
41 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 1.34116258 |
42 | Homologous recombination_Homo sapiens_hsa03440 | 1.29145329 |
43 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 1.27790362 |
44 | RNA degradation_Homo sapiens_hsa03018 | 1.27149315 |
45 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 1.26827834 |
46 | GnRH signaling pathway_Homo sapiens_hsa04912 | 1.26112074 |
47 | Hippo signaling pathway_Homo sapiens_hsa04390 | 1.24826103 |
48 | RNA transport_Homo sapiens_hsa03013 | 1.24180024 |
49 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 1.23624637 |
50 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.22598867 |
51 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 1.21731275 |
52 | Gap junction_Homo sapiens_hsa04540 | 1.21580620 |
53 | cAMP signaling pathway_Homo sapiens_hsa04024 | 1.19563139 |
54 | RNA polymerase_Homo sapiens_hsa03020 | 1.19061660 |
55 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.18881291 |
56 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.17243172 |
57 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 1.15342712 |
58 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 1.15307661 |
59 | Basal cell carcinoma_Homo sapiens_hsa05217 | 1.14978901 |
60 | ErbB signaling pathway_Homo sapiens_hsa04012 | 1.13371133 |
61 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 1.11732506 |
62 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 1.11341521 |
63 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.10514219 |
64 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 1.08503085 |
65 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.05127088 |
66 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.04659087 |
67 | Melanogenesis_Homo sapiens_hsa04916 | 1.02732076 |
68 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 1.00857419 |
69 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 1.00416907 |
70 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.99576380 |
71 | DNA replication_Homo sapiens_hsa03030 | 0.99249163 |
72 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.98086353 |
73 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.98003045 |
74 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.95657510 |
75 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.93637574 |
76 | Cell cycle_Homo sapiens_hsa04110 | 0.92290548 |
77 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.89614121 |
78 | Glioma_Homo sapiens_hsa05214 | 0.86462092 |
79 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 0.86437107 |
80 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 0.85515771 |
81 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.85252107 |
82 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.83090093 |
83 | Proteasome_Homo sapiens_hsa03050 | 0.82871955 |
84 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.82244881 |
85 | Tight junction_Homo sapiens_hsa04530 | 0.81508699 |
86 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.79629216 |
87 | Spliceosome_Homo sapiens_hsa03040 | 0.77730319 |
88 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.76838900 |
89 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.73736540 |
90 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.73581420 |
91 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.73514827 |
92 | Base excision repair_Homo sapiens_hsa03410 | 0.73186740 |
93 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.72938914 |
94 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.71588168 |
95 | Alzheimers disease_Homo sapiens_hsa05010 | 0.70099131 |
96 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.69986848 |
97 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 0.69404386 |
98 | Circadian rhythm_Homo sapiens_hsa04710 | 0.68959989 |
99 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.67379280 |
100 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.65815948 |
101 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.65496049 |
102 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.64184459 |
103 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.61583302 |
104 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.59989052 |
105 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.59836861 |
106 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.59520151 |
107 | Purine metabolism_Homo sapiens_hsa00230 | 0.59393525 |
108 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.57553469 |
109 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.56891637 |
110 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.55172645 |
111 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.53631782 |
112 | Alcoholism_Homo sapiens_hsa05034 | 0.52744288 |
113 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.51321215 |
114 | Adherens junction_Homo sapiens_hsa04520 | 0.50427943 |
115 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.49778878 |
116 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.49335706 |
117 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.49294293 |
118 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.49026564 |
119 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 0.48883797 |
120 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.48768904 |
121 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.48732424 |
122 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.48658783 |
123 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.48183573 |
124 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.47891066 |
125 | Retinol metabolism_Homo sapiens_hsa00830 | 0.47075088 |
126 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.46762834 |
127 | Endometrial cancer_Homo sapiens_hsa05213 | 0.46735294 |
128 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.46117876 |
129 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.45375188 |
130 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.44257822 |
131 | Parkinsons disease_Homo sapiens_hsa05012 | 0.44058854 |
132 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.43929174 |
133 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.42644587 |
134 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.42415711 |
135 | Phagosome_Homo sapiens_hsa04145 | 0.42008972 |
136 | Huntingtons disease_Homo sapiens_hsa05016 | 0.41747404 |
137 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.40768942 |
138 | Melanoma_Homo sapiens_hsa05218 | 0.40394297 |
139 | Colorectal cancer_Homo sapiens_hsa05210 | 0.37220408 |
140 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.36636095 |
141 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.36563472 |
142 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.36218551 |
143 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.36199222 |
144 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 0.32703738 |
145 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.32593121 |
146 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.32403149 |
147 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.31044146 |
148 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.28998869 |
149 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.28516158 |
150 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.25073067 |
151 | Prion diseases_Homo sapiens_hsa05020 | 0.22805171 |
152 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.22556296 |
153 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.22365049 |
154 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.22216837 |