UNC79

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: The NALCN channel is responsible for Na(+) leak currents. The protein encoded by this gene, along with UNC80, is an accessory subunit of the NALCN channel that contributes to the Ca(2+) sensitivity of the channel. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1regulation of short-term neuronal synaptic plasticity (GO:0048172)5.59694122
2positive regulation of excitatory postsynaptic membrane potential (GO:2000463)5.27047358
3vocalization behavior (GO:0071625)5.06364813
4regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act5.02808534
5ionotropic glutamate receptor signaling pathway (GO:0035235)4.81609474
6synaptic vesicle exocytosis (GO:0016079)4.78907069
7neuron cell-cell adhesion (GO:0007158)4.78793249
8positive regulation of calcium ion-dependent exocytosis (GO:0045956)4.77676103
9protein localization to synapse (GO:0035418)4.69714346
10regulation of glutamate receptor signaling pathway (GO:1900449)4.67455103
11regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)4.56770091
12locomotory exploration behavior (GO:0035641)4.55167723
13synaptic transmission, glutamatergic (GO:0035249)4.42446639
14regulation of synaptic vesicle exocytosis (GO:2000300)4.40324604
15glutamate receptor signaling pathway (GO:0007215)4.38804548
16synaptic vesicle maturation (GO:0016188)4.36606782
17pyrimidine nucleobase catabolic process (GO:0006208)4.35986959
18neurotransmitter-gated ion channel clustering (GO:0072578)4.35759889
19synaptic vesicle docking involved in exocytosis (GO:0016081)4.29047276
20glutamate secretion (GO:0014047)4.22047899
21neuron-neuron synaptic transmission (GO:0007270)4.21150545
22presynaptic membrane assembly (GO:0097105)4.07480581
23regulation of inhibitory postsynaptic membrane potential (GO:0060080)4.04529482
24regulation of synaptic vesicle transport (GO:1902803)4.03312800
25regulation of neuronal synaptic plasticity (GO:0048168)3.99417673
26regulation of long-term neuronal synaptic plasticity (GO:0048169)3.99333739
27nucleobase catabolic process (GO:0046113)3.98514166
28membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.96263856
29neuronal action potential propagation (GO:0019227)3.92042957
30postsynaptic membrane organization (GO:0001941)3.84733730
31regulation of excitatory postsynaptic membrane potential (GO:0060079)3.82553663
32presynaptic membrane organization (GO:0097090)3.82187736
33long-term memory (GO:0007616)3.80654326
34regulation of synapse structural plasticity (GO:0051823)3.80330519
35neurotransmitter secretion (GO:0007269)3.79140315
36neuron recognition (GO:0008038)3.78582414
37negative regulation of cytosolic calcium ion concentration (GO:0051481)3.77113289
38exploration behavior (GO:0035640)3.75333088
39positive regulation of membrane potential (GO:0045838)3.71549343
40regulation of postsynaptic membrane potential (GO:0060078)3.70730432
41transmission of nerve impulse (GO:0019226)3.66739771
42gamma-aminobutyric acid transport (GO:0015812)3.64475192
43G-protein coupled glutamate receptor signaling pathway (GO:0007216)3.61080336
44gamma-aminobutyric acid signaling pathway (GO:0007214)3.58066885
45positive regulation of synaptic transmission, GABAergic (GO:0032230)3.57563974
46dendritic spine morphogenesis (GO:0060997)3.57072318
47startle response (GO:0001964)3.55803785
48axonal fasciculation (GO:0007413)3.55657979
49behavioral response to nicotine (GO:0035095)3.49056300
50regulation of synaptic transmission, glutamatergic (GO:0051966)3.47386106
51positive regulation of synapse maturation (GO:0090129)3.44903021
52positive regulation of synaptic transmission, glutamatergic (GO:0051968)3.41755656
53regulation of respiratory gaseous exchange by neurological system process (GO:0002087)3.39079268
54long-term synaptic potentiation (GO:0060291)3.36320985
55negative regulation of synaptic transmission, GABAergic (GO:0032229)3.35448720
56synaptic vesicle endocytosis (GO:0048488)3.35297146
57regulation of synaptic plasticity (GO:0048167)3.33502067
58neuronal action potential (GO:0019228)3.32291703
59positive regulation of neurotransmitter secretion (GO:0001956)3.30478735
60negative regulation of synaptic transmission, glutamatergic (GO:0051967)3.30409215
61proline transport (GO:0015824)3.26927473
62auditory behavior (GO:0031223)3.26031357
63cerebellar Purkinje cell differentiation (GO:0021702)3.25497831
64innervation (GO:0060384)3.25318715
65regulation of neurotransmitter secretion (GO:0046928)3.24589564
66layer formation in cerebral cortex (GO:0021819)3.22518627
67protein polyglutamylation (GO:0018095)3.22057011
68regulation of vesicle fusion (GO:0031338)3.22054116
69synapse assembly (GO:0007416)3.20988469
70membrane hyperpolarization (GO:0060081)3.20651925
71neurotransmitter transport (GO:0006836)3.18744868
72response to auditory stimulus (GO:0010996)3.18723180
73membrane depolarization (GO:0051899)3.18567568
74membrane depolarization during action potential (GO:0086010)3.18247660
75detection of calcium ion (GO:0005513)3.18178672
76regulation of dendritic spine morphogenesis (GO:0061001)3.15249571
77positive regulation of neurotransmitter transport (GO:0051590)3.14696165
78dendrite morphogenesis (GO:0048813)3.14054922
79behavioral defense response (GO:0002209)3.13459197
80behavioral fear response (GO:0001662)3.13459197
81response to histamine (GO:0034776)3.11974872
82negative regulation of dendrite development (GO:2000171)3.10232281
83learning (GO:0007612)3.10000579
84regulation of synapse maturation (GO:0090128)3.08954290
85neuronal ion channel clustering (GO:0045161)3.07391327
86regulation of respiratory system process (GO:0044065)3.06431396
87righting reflex (GO:0060013)3.05336671
88positive regulation of dendritic spine morphogenesis (GO:0061003)3.05278707
89mechanosensory behavior (GO:0007638)3.03080483
90response to pheromone (GO:0019236)3.01426124
91regulation of neurotransmitter transport (GO:0051588)3.00335160
92fear response (GO:0042596)2.97664199
93central nervous system projection neuron axonogenesis (GO:0021952)2.95856316
94prepulse inhibition (GO:0060134)2.94523077
95G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)2.91998593
96synaptic transmission (GO:0007268)2.91297352
97regulation of synaptic transmission, GABAergic (GO:0032228)2.90052688
98establishment of mitochondrion localization (GO:0051654)2.88087788
99long term synaptic depression (GO:0060292)2.88023987
100inositol phosphate catabolic process (GO:0071545)2.87783828
101cerebellar granule cell differentiation (GO:0021707)2.86257884
102central nervous system neuron axonogenesis (GO:0021955)2.85957767
103positive regulation of synaptic transmission (GO:0050806)2.85817646
104chemosensory behavior (GO:0007635)2.85420370
105striatum development (GO:0021756)2.85363897
106female mating behavior (GO:0060180)2.85251673
107regulation of neurotransmitter levels (GO:0001505)2.85234128
108regulation of glutamate secretion (GO:0014048)2.84979834
109positive regulation of synapse assembly (GO:0051965)2.84054322
110regulation of female receptivity (GO:0045924)2.83653673
111cellular potassium ion homeostasis (GO:0030007)2.82972691
112limb bud formation (GO:0060174)2.79117756
113regulation of penile erection (GO:0060405)2.78670856
114regulation of calcium ion-dependent exocytosis (GO:0017158)2.74655536
115regulation of dendritic spine development (GO:0060998)2.72130963
116cell migration in hindbrain (GO:0021535)2.71208300
117adult walking behavior (GO:0007628)2.70763104
118positive regulation of dendritic spine development (GO:0060999)2.70407630
119glycosphingolipid biosynthetic process (GO:0006688)2.68630577
120action potential (GO:0001508)2.68445130
121neuromuscular synaptic transmission (GO:0007274)2.65708028
122reflex (GO:0060004)2.65629246
123serotonin metabolic process (GO:0042428)2.64870233
124retinal ganglion cell axon guidance (GO:0031290)2.62166241
125atrial cardiac muscle cell action potential (GO:0086014)2.59513231
126C4-dicarboxylate transport (GO:0015740)2.59422661
127regulation of action potential (GO:0098900)2.58149390
128retinal cone cell development (GO:0046549)2.55216062
129synapse organization (GO:0050808)2.55125646
130* adult behavior (GO:0030534)2.54954687
131positive regulation of phosphoprotein phosphatase activity (GO:0032516)2.54518314
132calcium ion-dependent exocytosis (GO:0017156)2.53852267
133cAMP catabolic process (GO:0006198)2.52505473
134acrosome reaction (GO:0007340)2.51714682
135primary amino compound metabolic process (GO:1901160)2.50467624
136regulation of synapse assembly (GO:0051963)2.49091673

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.92192448
2GBX2_23144817_ChIP-Seq_PC3_Human4.24810949
3SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.95455916
4JARID2_20064375_ChIP-Seq_MESCs_Mouse2.91082023
5SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.85347081
6* REST_21632747_ChIP-Seq_MESCs_Mouse2.56074945
7EZH2_27304074_Chip-Seq_ESCs_Mouse2.54781214
8JARID2_20075857_ChIP-Seq_MESCs_Mouse2.51529757
9SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.48411603
10RNF2_18974828_ChIP-Seq_MESCs_Mouse2.47263808
11EZH2_18974828_ChIP-Seq_MESCs_Mouse2.47263808
12SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.46645791
13SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.32592892
14EED_16625203_ChIP-ChIP_MESCs_Mouse2.32023604
15SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.26558382
16MTF2_20144788_ChIP-Seq_MESCs_Mouse2.25328413
17DROSHA_22980978_ChIP-Seq_HELA_Human2.22856786
18EZH2_27294783_Chip-Seq_ESCs_Mouse2.12019338
19GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.11082927
20* RARB_27405468_Chip-Seq_BRAIN_Mouse2.09929717
21RNF2_27304074_Chip-Seq_ESCs_Mouse2.09288560
22SUZ12_27294783_Chip-Seq_ESCs_Mouse2.06705573
23CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.05499561
24ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.99719624
25CTBP2_25329375_ChIP-Seq_LNCAP_Human1.98637473
26REST_18959480_ChIP-ChIP_MESCs_Mouse1.94867420
27ZFP57_27257070_Chip-Seq_ESCs_Mouse1.94017946
28FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.91829120
29* SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.87166650
30GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.85063416
31TAF15_26573619_Chip-Seq_HEK293_Human1.84111616
32PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.79229795
33SMAD4_21799915_ChIP-Seq_A2780_Human1.77147975
34NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.75010049
35CTBP1_25329375_ChIP-Seq_LNCAP_Human1.74613764
36AR_21572438_ChIP-Seq_LNCaP_Human1.74038610
37P300_19829295_ChIP-Seq_ESCs_Human1.66262210
38TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.65634670
39IKZF1_21737484_ChIP-ChIP_HCT116_Human1.61956057
40BMI1_23680149_ChIP-Seq_NPCS_Mouse1.61559242
41CBX2_27304074_Chip-Seq_ESCs_Mouse1.59365333
42IGF1R_20145208_ChIP-Seq_DFB_Human1.57685581
43POU3F2_20337985_ChIP-ChIP_501MEL_Human1.57080361
44SALL1_21062744_ChIP-ChIP_HESCs_Human1.54521201
45SMAD3_21741376_ChIP-Seq_EPCs_Human1.52945997
46EWS_26573619_Chip-Seq_HEK293_Human1.52534438
47SMAD_19615063_ChIP-ChIP_OVARY_Human1.46333099
48PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.46247326
49IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.43938648
50CBP_20019798_ChIP-Seq_JUKART_Human1.43938648
51RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.41120368
52FLI1_27457419_Chip-Seq_LIVER_Mouse1.41064854
53SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.37776238
54STAT3_23295773_ChIP-Seq_U87_Human1.37629745
55RNF2_27304074_Chip-Seq_NSC_Mouse1.37444100
56ZNF274_21170338_ChIP-Seq_K562_Hela1.37296414
57PIAS1_25552417_ChIP-Seq_VCAP_Human1.34855751
58OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.32981626
59AR_25329375_ChIP-Seq_VCAP_Human1.31425538
60TOP2B_26459242_ChIP-Seq_MCF-7_Human1.30309069
61SOX2_21211035_ChIP-Seq_LN229_Gbm1.29669885
62E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.26125493
63TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.24982114
64FUS_26573619_Chip-Seq_HEK293_Human1.24029472
65EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.23952398
66TCF4_23295773_ChIP-Seq_U87_Human1.23884226
67TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.22157660
68TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.21997644
69P53_22127205_ChIP-Seq_FIBROBLAST_Human1.21196496
70NANOG_18555785_Chip-Seq_ESCs_Mouse1.20575179
71MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.19870940
72ERG_21242973_ChIP-ChIP_JURKAT_Human1.18987974
73AR_19668381_ChIP-Seq_PC3_Human1.18465952
74SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.18387640
75HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.17641153
76NR3C1_23031785_ChIP-Seq_PC12_Mouse1.17611844
77MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.17165290
78RING1B_27294783_Chip-Seq_ESCs_Mouse1.16694476
79AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.16285067
80CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.15406632
81ZNF217_24962896_ChIP-Seq_MCF-7_Human1.14861184
82PCGF2_27294783_Chip-Seq_ESCs_Mouse1.14329488
83KLF5_20875108_ChIP-Seq_MESCs_Mouse1.13808177
84RUNX2_22187159_ChIP-Seq_PCA_Human1.13725592
85VDR_22108803_ChIP-Seq_LS180_Human1.12361670
86CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.10728053
87NR3C1_21868756_ChIP-Seq_MCF10A_Human1.10569640
88FLI1_21867929_ChIP-Seq_TH2_Mouse1.10280555
89TCF4_22108803_ChIP-Seq_LS180_Human1.10092755
90ARNT_22903824_ChIP-Seq_MCF-7_Human1.10005964
91YAP1_20516196_ChIP-Seq_MESCs_Mouse1.09775084
92KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.09115499
93POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.08532851
94TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.08532851
95VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.08394780
96AHR_22903824_ChIP-Seq_MCF-7_Human1.07173988
97RING1B_27294783_Chip-Seq_NPCs_Mouse1.06760102
98ER_23166858_ChIP-Seq_MCF-7_Human1.06003819
99TAL1_26923725_Chip-Seq_HPCs_Mouse1.05857334
100EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.05824367
101SMAD4_21741376_ChIP-Seq_EPCs_Human1.04490181
102E2F1_18555785_Chip-Seq_ESCs_Mouse1.04020246
103* KDM2B_26808549_Chip-Seq_REH_Human1.03973622
104LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.03578702
105UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.03140416
106PRDM14_20953172_ChIP-Seq_ESCs_Human1.03002096
107* RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.02320647
108P53_22387025_ChIP-Seq_ESCs_Mouse1.01282832
109CDX2_19796622_ChIP-Seq_MESCs_Mouse1.00819923
110WT1_25993318_ChIP-Seq_PODOCYTE_Human1.00518536
111MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.00418740
112SMAD3_21741376_ChIP-Seq_ESCs_Human1.00392070
113SUZ12_27294783_Chip-Seq_NPCs_Mouse1.00183450
114* MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.00108228
115TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse0.99796769
116TP53_22573176_ChIP-Seq_HFKS_Human0.99733941
117TP53_18474530_ChIP-ChIP_U2OS_Human0.99198043
118TP53_16413492_ChIP-PET_HCT116_Human0.98576615
119TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.98292596
120CMYC_18555785_Chip-Seq_ESCs_Mouse0.97909878
121BCAT_22108803_ChIP-Seq_LS180_Human0.96950180
122PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.96800310
123BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse0.95314007

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity5.50567062
2MP0003880_abnormal_central_pattern4.74847393
3MP0003635_abnormal_synaptic_transmissio3.77663916
4MP0004270_analgesia3.43922803
5* MP0009745_abnormal_behavioral_response3.15603546
6MP0002063_abnormal_learning/memory/cond3.12873429
7MP0002822_catalepsy3.09844889
8MP0005423_abnormal_somatic_nervous2.88548244
9MP0002064_seizures2.86464291
10MP0009046_muscle_twitch2.77200759
11MP0002572_abnormal_emotion/affect_behav2.76292649
12MP0001968_abnormal_touch/_nociception2.74742707
13MP0001486_abnormal_startle_reflex2.51261155
14MP0002734_abnormal_mechanical_nocicepti2.44163629
15MP0005646_abnormal_pituitary_gland2.42611836
16MP0002272_abnormal_nervous_system2.42164251
17MP0005645_abnormal_hypothalamus_physiol2.19525609
18MP0002736_abnormal_nociception_after2.18193140
19MP0002735_abnormal_chemical_nociception2.16957404
20MP0001501_abnormal_sleep_pattern2.14959924
21MP0006276_abnormal_autonomic_nervous2.06509306
22MP0008877_abnormal_DNA_methylation2.01842132
23MP0001440_abnormal_grooming_behavior1.98536893
24MP0001188_hyperpigmentation1.96942742
25MP0003787_abnormal_imprinting1.94790835
26MP0000778_abnormal_nervous_system1.93505797
27MP0002067_abnormal_sensory_capabilities1.92276953
28MP0002909_abnormal_adrenal_gland1.92011280
29MP0002557_abnormal_social/conspecific_i1.91353342
30MP0002184_abnormal_innervation1.89749982
31MP0002733_abnormal_thermal_nociception1.86019161
32MP0001970_abnormal_pain_threshold1.80549257
33MP0001984_abnormal_olfaction1.78934389
34MP0010386_abnormal_urinary_bladder1.74198794
35MP0002102_abnormal_ear_morphology1.73210322
36MP0009780_abnormal_chondrocyte_physiolo1.69615812
37MP0005386_behavior/neurological_phenoty1.68222948
38MP0004924_abnormal_behavior1.68222948
39MP0008569_lethality_at_weaning1.64869813
40MP0001529_abnormal_vocalization1.62464803
41MP0003879_abnormal_hair_cell1.59988425
42MP0001502_abnormal_circadian_rhythm1.57430414
43MP0004811_abnormal_neuron_physiology1.55915827
44MP0003122_maternal_imprinting1.50463312
45MP0000955_abnormal_spinal_cord1.47312388
46MP0002638_abnormal_pupillary_reflex1.41849863
47MP0005551_abnormal_eye_electrophysiolog1.39244840
48MP0002882_abnormal_neuron_morphology1.39005264
49MP0006292_abnormal_olfactory_placode1.37793537
50MP0005409_darkened_coat_color1.33797188
51MP0000631_abnormal_neuroendocrine_gland1.28036975
52* MP0002066_abnormal_motor_capabilities/c1.27669126
53MP0000569_abnormal_digit_pigmentation1.26231126
54MP0004858_abnormal_nervous_system1.23798347
55MP0006072_abnormal_retinal_apoptosis1.22536246
56MP0001905_abnormal_dopamine_level1.20243798
57MP0004142_abnormal_muscle_tone1.19319020
58MP0003011_delayed_dark_adaptation1.12767760
59MP0002876_abnormal_thyroid_physiology1.07156339
60MP0004885_abnormal_endolymph1.06222769
61MP0004133_heterotaxia1.05985879
62MP0002152_abnormal_brain_morphology1.05532260
63MP0003633_abnormal_nervous_system1.05074549
64MP0004043_abnormal_pH_regulation0.99153478
65* MP0002069_abnormal_eating/drinking_beha0.98447274
66MP0001177_atelectasis0.96805246
67MP0002229_neurodegeneration0.96042443
68MP0003183_abnormal_peptide_metabolism0.95680657
69MP0003195_calcinosis0.95157629
70MP0003283_abnormal_digestive_organ0.93576238
71MP0001963_abnormal_hearing_physiology0.93087167
72MP0004742_abnormal_vestibular_system0.92626781
73MP0005394_taste/olfaction_phenotype0.92316020
74MP0005499_abnormal_olfactory_system0.92316020
75MP0005379_endocrine/exocrine_gland_phen0.89874501
76MP0004085_abnormal_heartbeat0.89327934
77MP0000013_abnormal_adipose_tissue0.88845171
78MP0003631_nervous_system_phenotype0.87198658
79MP0002752_abnormal_somatic_nervous0.85783498
80MP0004145_abnormal_muscle_electrophysio0.85082403
81MP0005253_abnormal_eye_physiology0.83282822
82MP0002928_abnormal_bile_duct0.81990724
83MP0005171_absent_coat_pigmentation0.77465171
84MP0003698_abnormal_male_reproductive0.76417222
85MP0002090_abnormal_vision0.75579096
86MP0001485_abnormal_pinna_reflex0.75457258
87MP0003137_abnormal_impulse_conducting0.74707129
88MP0005535_abnormal_body_temperature0.74240903
89MP0003329_amyloid_beta_deposits0.74020779
90MP0000026_abnormal_inner_ear0.73354514
91MP0005187_abnormal_penis_morphology0.73135192
92MP0005195_abnormal_posterior_eye0.72600882
93MP0005084_abnormal_gallbladder_morpholo0.71968060
94MP0003121_genomic_imprinting0.71878036
95MP0003119_abnormal_digestive_system0.71561910
96MP0002693_abnormal_pancreas_physiology0.70153060
97MP0001664_abnormal_digestion0.69199226
98MP0000427_abnormal_hair_cycle0.68543496
99MP0008961_abnormal_basal_metabolism0.67629557
100MP0002837_dystrophic_cardiac_calcinosis0.66201157
101MP0005410_abnormal_fertilization0.66158854
102MP0001299_abnormal_eye_distance/0.65725318
103MP0000678_abnormal_parathyroid_gland0.64968000
104MP0005367_renal/urinary_system_phenotyp0.64839677
105MP0000516_abnormal_urinary_system0.64839677
106MP0003890_abnormal_embryonic-extraembry0.64654719
107MP0001986_abnormal_taste_sensitivity0.64449695
108MP0008789_abnormal_olfactory_epithelium0.63997260
109MP0003634_abnormal_glial_cell0.63955279
110MP0004215_abnormal_myocardial_fiber0.63434068
111MP0002234_abnormal_pharynx_morphology0.62376189
112MP0002751_abnormal_autonomic_nervous0.62283118
113MP0008872_abnormal_physiological_respon0.61510528
114MP0001943_abnormal_respiration0.59017194
115MP0003861_abnormal_nervous_system0.58574343
116MP0001944_abnormal_pancreas_morphology0.57268380
117MP0008874_decreased_physiological_sensi0.56441837
118MP0003632_abnormal_nervous_system0.54595359

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)7.46709063
2Myokymia (HP:0002411)5.45071079
3Focal seizures (HP:0007359)5.15575697
4Epileptic encephalopathy (HP:0200134)5.04608258
5Febrile seizures (HP:0002373)5.01628924
6Atonic seizures (HP:0010819)4.18107666
7Progressive cerebellar ataxia (HP:0002073)4.05412945
8Visual hallucinations (HP:0002367)3.99973337
9Hyperventilation (HP:0002883)3.92138565
10Absence seizures (HP:0002121)3.82755619
11Broad-based gait (HP:0002136)3.68240888
12Dialeptic seizures (HP:0011146)3.58841423
13Generalized tonic-clonic seizures (HP:0002069)3.45261321
14Gaze-evoked nystagmus (HP:0000640)3.35790219
15Protruding tongue (HP:0010808)3.32718322
16Truncal ataxia (HP:0002078)3.06128428
17Epileptiform EEG discharges (HP:0011182)2.97112320
18Excessive salivation (HP:0003781)2.95736329
19Drooling (HP:0002307)2.95736329
20Impaired smooth pursuit (HP:0007772)2.95281693
21Action tremor (HP:0002345)2.91658405
22Poor eye contact (HP:0000817)2.90220696
23Intestinal atresia (HP:0011100)2.84860482
24Type II lissencephaly (HP:0007260)2.81300172
25Amblyopia (HP:0000646)2.78711470
26EEG with generalized epileptiform discharges (HP:0011198)2.77130531
27Lissencephaly (HP:0001339)2.76532263
28Anxiety (HP:0000739)2.73880881
29Depression (HP:0000716)2.67599671
30Dysdiadochokinesis (HP:0002075)2.64275896
31Elevated circulating parathyroid hormone (PTH) level (HP:0003165)2.63727659
32Hypothermia (HP:0002045)2.60080651
33Abnormal eating behavior (HP:0100738)2.57733276
34Impaired vibration sensation in the lower limbs (HP:0002166)2.56810433
35Pancreatic fibrosis (HP:0100732)2.56377849
36Supranuclear gaze palsy (HP:0000605)2.54086455
37Hypsarrhythmia (HP:0002521)2.53208290
38Hemiparesis (HP:0001269)2.52732182
39Nephronophthisis (HP:0000090)2.52497680
40Pancreatic cysts (HP:0001737)2.51403030
41Blue irides (HP:0000635)2.49521884
42Abnormal social behavior (HP:0012433)2.49113881
43Impaired social interactions (HP:0000735)2.49113881
44Abnormality of ocular smooth pursuit (HP:0000617)2.47482571
45Ankle clonus (HP:0011448)2.47291624
46Dysmetria (HP:0001310)2.46600038
47Scanning speech (HP:0002168)2.45705722
48Absent speech (HP:0001344)2.39768764
49Decreased circulating renin level (HP:0003351)2.38243099
50Genetic anticipation (HP:0003743)2.35316664
51Progressive inability to walk (HP:0002505)2.34475091
52Pachygyria (HP:0001302)2.33350668
53Abnormality of the labia minora (HP:0012880)2.32964228
54Agitation (HP:0000713)2.32903575
55Urinary bladder sphincter dysfunction (HP:0002839)2.28267617
56True hermaphroditism (HP:0010459)2.27875028
57Gait imbalance (HP:0002141)2.25133557
58Abnormality of the renal medulla (HP:0100957)2.23434605
59Genital tract atresia (HP:0001827)2.23417220
60Limb dystonia (HP:0002451)2.21994840
61Spastic tetraplegia (HP:0002510)2.21520435
62Stereotypic behavior (HP:0000733)2.20919836
63Failure to thrive in infancy (HP:0001531)2.19433289
64Generalized hypopigmentation of hair (HP:0011358)2.17211278
65Muscular hypotonia of the trunk (HP:0008936)2.16775728
66Abnormality of the corticospinal tract (HP:0002492)2.16219550
67Inability to walk (HP:0002540)2.15343299
68Fetal akinesia sequence (HP:0001989)2.14427344
69Amyotrophic lateral sclerosis (HP:0007354)2.13702723
70Medial flaring of the eyebrow (HP:0010747)2.13192429
71Retinal dysplasia (HP:0007973)2.12519789
72Polyphagia (HP:0002591)2.11900779
73Abnormality of the renal cortex (HP:0011035)2.11349104
74Prolonged QT interval (HP:0001657)2.10102357
75Abnormal EKG (HP:0003115)2.07852238
76Vaginal atresia (HP:0000148)2.07315743
77Abolished electroretinogram (ERG) (HP:0000550)2.07154976
78Abnormality of salivation (HP:0100755)2.04752948
79Postural instability (HP:0002172)2.03347096
80Abnormality of calcium-phosphate metabolism (HP:0100530)2.02284520
81Mutism (HP:0002300)2.01710460
82Absent/shortened dynein arms (HP:0200106)2.01482289
83Dynein arm defect of respiratory motile cilia (HP:0012255)2.01482289
84Intention tremor (HP:0002080)2.00664613
85Chronic hepatic failure (HP:0100626)1.98317767
86Abnormal drinking behavior (HP:0030082)1.96211144
87Polydipsia (HP:0001959)1.96211144
88Papilledema (HP:0001085)1.93648537
89Bradykinesia (HP:0002067)1.93425084
90Congenital primary aphakia (HP:0007707)1.92908092
91Diplopia (HP:0000651)1.91134738
92Abnormality of binocular vision (HP:0011514)1.91134738
93Torticollis (HP:0000473)1.90633595
94Nephrogenic diabetes insipidus (HP:0009806)1.90253239
95Abnormality of the lower motor neuron (HP:0002366)1.90056427
96Thickened helices (HP:0000391)1.89494214
97Degeneration of the lateral corticospinal tracts (HP:0002314)1.88968761
98Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)1.88968761
99Exotropia (HP:0000577)1.88527116
100Central scotoma (HP:0000603)1.88318639
101Intellectual disability, severe (HP:0010864)1.87809270
102Widely spaced teeth (HP:0000687)1.87587004
103Fair hair (HP:0002286)1.87263425
104Abnormal hair whorl (HP:0010721)1.86438204
105Aqueductal stenosis (HP:0002410)1.85238858
106Focal dystonia (HP:0004373)1.84936551
107Optic nerve hypoplasia (HP:0000609)1.84933252
108Sleep apnea (HP:0010535)1.83752281
109Ketoacidosis (HP:0001993)1.83596060
110Status epilepticus (HP:0002133)1.83406658
111Aplasia/Hypoplasia of the brainstem (HP:0007362)1.83285285
112Hypoplasia of the brainstem (HP:0002365)1.83285285
113Spastic gait (HP:0002064)1.82184102
114Ventricular fibrillation (HP:0001663)1.81986459
115Specific learning disability (HP:0001328)1.80918421
116Impaired vibratory sensation (HP:0002495)1.80752166
117Cortical visual impairment (HP:0100704)1.78954096
118Hepatoblastoma (HP:0002884)1.78503840
119Narrow forehead (HP:0000341)1.75989030
120Gait ataxia (HP:0002066)1.74467654
121Congenital stationary night blindness (HP:0007642)1.74159682
122Congenital sensorineural hearing impairment (HP:0008527)1.74105043
123Abnormality of midbrain morphology (HP:0002418)1.74088499
124Molar tooth sign on MRI (HP:0002419)1.74088499
125Gastrointestinal atresia (HP:0002589)1.73936183
126Cerebellar dysplasia (HP:0007033)1.73601073
127Gastroesophageal reflux (HP:0002020)1.72318396
128Pheochromocytoma (HP:0002666)1.72045246
129Volvulus (HP:0002580)1.71370502
130Attenuation of retinal blood vessels (HP:0007843)1.71152364
131Open mouth (HP:0000194)1.70995317
132Intellectual disability, progressive (HP:0006887)1.70669575
133Poor suck (HP:0002033)1.70578858
134Bradycardia (HP:0001662)1.70572320
135Megalencephaly (HP:0001355)1.70543578
136Large for gestational age (HP:0001520)1.70400798
137Incomplete penetrance (HP:0003829)1.70048051
138Renal cortical cysts (HP:0000803)1.69831974
139Deeply set eye (HP:0000490)1.68867232
140Esotropia (HP:0000565)1.68823115
141Hypoplasia of the corpus callosum (HP:0002079)1.68605111
142Oligodactyly (hands) (HP:0001180)1.68376620
143Generalized myoclonic seizures (HP:0002123)1.67604694
144Cystic liver disease (HP:0006706)1.67440888
145Hyperinsulinemic hypoglycemia (HP:0000825)1.67054749
146Cupped ear (HP:0000378)1.64023456

Predicted kinase interactions (KEA)

RankGene SetZ-score
1NTRK34.81062046
2EPHA44.51341066
3CASK3.42007500
4MARK13.21955308
5TNIK2.86069123
6MAP2K72.70687950
7MAP3K42.59375856
8MAP3K92.47079109
9NTRK22.37440806
10DAPK22.22645918
11MAP4K22.08230449
12MINK12.04732241
13MAPK131.80821531
14MAP3K121.79068151
15RIPK41.71581510
16PRPF4B1.62630943
17KSR11.59126738
18PRKD31.58499669
19PAK61.57001194
20TRIM281.51421655
21DAPK11.47934685
22DYRK21.45343355
23INSRR1.45194968
24NTRK11.42124291
25MAP2K41.41959472
26GRK11.41956597
27SGK21.41593582
28ACVR1B1.41370743
29CDK51.40324609
30UHMK11.39373660
31SIK21.29204932
32SGK4941.28464541
33SGK2231.28464541
34ARAF1.27375002
35CAMKK11.24456390
36AKT31.23461931
37WNK31.20619939
38BMPR21.19743389
39PLK21.17904358
40SIK31.14058690
41PRKCG1.13614706
42KSR21.11208160
43STK381.09001574
44FES1.08586801
45CSNK1G11.07194333
46CAMKK21.06776171
47CAMK2A1.05854861
48CAMK2B1.03337998
49SGK31.01943584
50MAP3K130.99569592
51GRK50.99537364
52CSNK1G30.99194748
53EPHA30.97556674
54CDK190.95055351
55MARK20.94810671
56MAP3K20.91443023
57DYRK1A0.89295567
58STK38L0.87673352
59CSNK1A1L0.85982758
60SGK10.81228472
61CAMK10.81211512
62NEK60.80645714
63STK110.75987177
64PRKCH0.75054723
65PRKCE0.73825413
66CAMK1G0.71129738
67BRAF0.70593666
68PNCK0.69950614
69CDK30.69359377
70CDC42BPA0.68947788
71MAP2K60.68270160
72ERBB30.67585218
73BCR0.66197362
74TNK20.65755934
75RAF10.63082791
76CDK180.62066202
77CSNK1G20.62055894
78PINK10.61612899
79NUAK10.58054250
80CDK150.57063707
81PKN10.57017640
82CAMK2D0.56773404
83TYRO30.55902107
84PAK30.55363901
85YES10.54158878
86PHKG10.54080551
87PHKG20.54080551
88DYRK30.53900084
89ADRBK10.52110463
90PRKD20.51921081
91CDK140.51732850
92PTK2B0.51328777
93STK390.50771966
94IRAK20.49808436
95OXSR10.49671103
96MAP3K10.48265098
97CDK11A0.47923037
98CAMK40.47255579
99PRKAA10.47199181
100WNK40.47054664
101RPS6KA20.46871291
102HIPK20.46850427
103MKNK20.46084060
104RPS6KA30.45991770
105RET0.45938412
106GRK70.45787218
107WNK10.45199195
108MAPK100.43078319
109CSNK1A10.42892473
110TAOK30.42705100
111BMPR1B0.42063126
112CSNK1D0.41637948
113CAMK2G0.41275617
114FRK0.41035363
115ADRBK20.39794638
116PRKACA0.39746989
117FER0.39548885
118FGFR20.38814103
119CAMK1D0.38784293
120PRKG10.38271860
121PRKCZ0.37741750
122PRKACB0.37472456
123MAP3K70.37429370
124PRKCB0.35863846
125CSNK1E0.34996744
126CCNB10.34528463
127ROCK10.32505786
128PRKCA0.29313393
129ZAK0.28560928
130GSK3B0.25651014

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050334.15557893
2Synaptic vesicle cycle_Homo sapiens_hsa047213.01539417
3Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.86670009
4GABAergic synapse_Homo sapiens_hsa047272.84628087
5Circadian entrainment_Homo sapiens_hsa047132.80767160
6Morphine addiction_Homo sapiens_hsa050322.77225359
7Olfactory transduction_Homo sapiens_hsa047402.69641779
8Glutamatergic synapse_Homo sapiens_hsa047242.68051131
9Amphetamine addiction_Homo sapiens_hsa050312.53556789
10Insulin secretion_Homo sapiens_hsa049112.46561333
11Long-term potentiation_Homo sapiens_hsa047202.44946370
12Dopaminergic synapse_Homo sapiens_hsa047282.19614147
13Taste transduction_Homo sapiens_hsa047422.18810194
14Butanoate metabolism_Homo sapiens_hsa006502.10250790
15Serotonergic synapse_Homo sapiens_hsa047261.97956632
16Cocaine addiction_Homo sapiens_hsa050301.96876500
17Salivary secretion_Homo sapiens_hsa049701.96612456
18Cholinergic synapse_Homo sapiens_hsa047251.95907693
19Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.88000953
20Aldosterone synthesis and secretion_Homo sapiens_hsa049251.82446386
21Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.79287991
22Long-term depression_Homo sapiens_hsa047301.70449963
23Calcium signaling pathway_Homo sapiens_hsa040201.68588760
24Renin secretion_Homo sapiens_hsa049241.67463175
25Gastric acid secretion_Homo sapiens_hsa049711.56471468
26Oxytocin signaling pathway_Homo sapiens_hsa049211.55290387
27Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.53143939
28Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.41902356
29Phototransduction_Homo sapiens_hsa047441.41849997
30Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.40370742
31Type II diabetes mellitus_Homo sapiens_hsa049301.39174185
32Collecting duct acid secretion_Homo sapiens_hsa049661.38699303
33cAMP signaling pathway_Homo sapiens_hsa040241.36369568
34Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.31978439
35Phosphatidylinositol signaling system_Homo sapiens_hsa040701.29278497
36GnRH signaling pathway_Homo sapiens_hsa049121.26423412
37Axon guidance_Homo sapiens_hsa043601.23394730
38Gap junction_Homo sapiens_hsa045401.16913043
39Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.15485789
40Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.14053646
41Vibrio cholerae infection_Homo sapiens_hsa051101.13414244
42Ether lipid metabolism_Homo sapiens_hsa005651.12617793
43Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.11815411
44cGMP-PKG signaling pathway_Homo sapiens_hsa040221.02342904
45Pancreatic secretion_Homo sapiens_hsa049721.01860932
46Type I diabetes mellitus_Homo sapiens_hsa049401.01431711
47Estrogen signaling pathway_Homo sapiens_hsa049151.00571209
48Melanogenesis_Homo sapiens_hsa049160.97591776
49Oxidative phosphorylation_Homo sapiens_hsa001900.97174541
50Tryptophan metabolism_Homo sapiens_hsa003800.96732391
51ErbB signaling pathway_Homo sapiens_hsa040120.95272804
52Maturity onset diabetes of the young_Homo sapiens_hsa049500.94996666
53Circadian rhythm_Homo sapiens_hsa047100.94868752
54Vascular smooth muscle contraction_Homo sapiens_hsa042700.94297384
55Glioma_Homo sapiens_hsa052140.88341286
56Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.87123230
57Linoleic acid metabolism_Homo sapiens_hsa005910.84662067
58Nitrogen metabolism_Homo sapiens_hsa009100.83096190
59ABC transporters_Homo sapiens_hsa020100.81994966
60Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.81060875
61Selenocompound metabolism_Homo sapiens_hsa004500.80043473
62Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.77213292
63Protein export_Homo sapiens_hsa030600.77094362
64Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.76703642
65Inositol phosphate metabolism_Homo sapiens_hsa005620.76265784
66Primary bile acid biosynthesis_Homo sapiens_hsa001200.75900618
67Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.75317404
68Cardiac muscle contraction_Homo sapiens_hsa042600.74256061
69Phospholipase D signaling pathway_Homo sapiens_hsa040720.73407247
70Propanoate metabolism_Homo sapiens_hsa006400.72953354
71Choline metabolism in cancer_Homo sapiens_hsa052310.71455765
72beta-Alanine metabolism_Homo sapiens_hsa004100.71250729
73Thyroid hormone synthesis_Homo sapiens_hsa049180.70002821
74Fatty acid biosynthesis_Homo sapiens_hsa000610.69834457
75MAPK signaling pathway_Homo sapiens_hsa040100.69277124
76Carbohydrate digestion and absorption_Homo sapiens_hsa049730.66967346
77Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.66676996
78Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.66545748
79Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.66115379
80Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.65924768
81Dilated cardiomyopathy_Homo sapiens_hsa054140.65731170
82Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.63191632
83Alcoholism_Homo sapiens_hsa050340.63002615
84alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.62812208
85SNARE interactions in vesicular transport_Homo sapiens_hsa041300.61547050
86Ras signaling pathway_Homo sapiens_hsa040140.60023140
87Dorso-ventral axis formation_Homo sapiens_hsa043200.59666712
88Parkinsons disease_Homo sapiens_hsa050120.59144311
89Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.57182828
90Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.56272239
91Oocyte meiosis_Homo sapiens_hsa041140.55678481
92Wnt signaling pathway_Homo sapiens_hsa043100.54046269
93Vitamin B6 metabolism_Homo sapiens_hsa007500.54005354
94Ovarian steroidogenesis_Homo sapiens_hsa049130.53605177
95Fatty acid metabolism_Homo sapiens_hsa012120.53337745
96Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.52315203
97Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.51950845
98Rap1 signaling pathway_Homo sapiens_hsa040150.51346343
99Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.50999639
100Glucagon signaling pathway_Homo sapiens_hsa049220.50175055
101Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.49960917
102Sphingolipid metabolism_Homo sapiens_hsa006000.48304142
103Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.48059734
104Peroxisome_Homo sapiens_hsa041460.46972158
105Thyroid hormone signaling pathway_Homo sapiens_hsa049190.46191360
106Regulation of autophagy_Homo sapiens_hsa041400.42042854
107Steroid biosynthesis_Homo sapiens_hsa001000.41883793
108Neurotrophin signaling pathway_Homo sapiens_hsa047220.41799515
109Basal transcription factors_Homo sapiens_hsa030220.40285558
110Longevity regulating pathway - mammal_Homo sapiens_hsa042110.38107662
111Endometrial cancer_Homo sapiens_hsa052130.37631639
112Huntingtons disease_Homo sapiens_hsa050160.36807410
113Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.36155287
114Sphingolipid signaling pathway_Homo sapiens_hsa040710.35484732
115Chemokine signaling pathway_Homo sapiens_hsa040620.35311535
116Steroid hormone biosynthesis_Homo sapiens_hsa001400.34940975
117African trypanosomiasis_Homo sapiens_hsa051430.34752605
118Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.34690908
119Alzheimers disease_Homo sapiens_hsa050100.33915872
120Bile secretion_Homo sapiens_hsa049760.33373655
121Non-small cell lung cancer_Homo sapiens_hsa052230.31191208
122Mineral absorption_Homo sapiens_hsa049780.30935212
123Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.30908644
124VEGF signaling pathway_Homo sapiens_hsa043700.29001424
125Endocytosis_Homo sapiens_hsa041440.28909387
126Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.28446274
127Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.28241412
128Rheumatoid arthritis_Homo sapiens_hsa053230.28207151
129Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.27627839
130Prolactin signaling pathway_Homo sapiens_hsa049170.26200935
131Prion diseases_Homo sapiens_hsa050200.25667500
132Renal cell carcinoma_Homo sapiens_hsa052110.23626146
133Insulin signaling pathway_Homo sapiens_hsa049100.22685590
134mTOR signaling pathway_Homo sapiens_hsa041500.22266898

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