UNC93A

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1regulation of dendritic cell antigen processing and presentation (GO:0002604)9.29919451
2regulation of cholesterol esterification (GO:0010872)8.72551138
3plasma lipoprotein particle assembly (GO:0034377)8.54087277
4very-low-density lipoprotein particle assembly (GO:0034379)7.68696966
5protein-lipid complex assembly (GO:0065005)7.56989394
6high-density lipoprotein particle remodeling (GO:0034375)7.56889011
7cholesterol efflux (GO:0033344)7.19862993
8negative regulation of fibrinolysis (GO:0051918)7.07810985
9macromolecular complex remodeling (GO:0034367)6.79868181
10plasma lipoprotein particle remodeling (GO:0034369)6.79868181
11protein-lipid complex remodeling (GO:0034368)6.79868181
12reverse cholesterol transport (GO:0043691)6.75830992
13positive regulation of antigen processing and presentation (GO:0002579)6.65491998
14regulation of T-helper 1 cell differentiation (GO:0045625)6.63126552
15triglyceride-rich lipoprotein particle remodeling (GO:0034370)6.58517777
16positive regulation of Cdc42 GTPase activity (GO:0043089)6.53117027
17protein carboxylation (GO:0018214)6.52063857
18peptidyl-glutamic acid carboxylation (GO:0017187)6.52063857
19regulation of fibrinolysis (GO:0051917)6.48999386
20positive regulation of heterotypic cell-cell adhesion (GO:0034116)6.45279858
21negative regulation of cholesterol transport (GO:0032375)6.22006794
22negative regulation of sterol transport (GO:0032372)6.22006794
23low-density lipoprotein particle remodeling (GO:0034374)6.12909470
24plasma lipoprotein particle organization (GO:0071827)6.07819064
25plasma lipoprotein particle clearance (GO:0034381)6.06175568
26negative regulation of lipase activity (GO:0060192)6.02702891
27regulation of protein activation cascade (GO:2000257)5.95671193
28protein-lipid complex subunit organization (GO:0071825)5.69781928
29positive regulation of T-helper 1 type immune response (GO:0002827)5.58339400
30regulation of antigen processing and presentation (GO:0002577)5.52719470
31regulation of complement activation (GO:0030449)5.30562474
32dendritic cell chemotaxis (GO:0002407)5.27147513
33erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)5.23475165
34L-phenylalanine catabolic process (GO:0006559)5.23475165
35glyoxylate metabolic process (GO:0046487)5.22563622
36blood coagulation, intrinsic pathway (GO:0007597)5.12952977
37positive regulation of granulocyte chemotaxis (GO:0071624)5.11700016
38positive regulation of interleukin-1 beta secretion (GO:0050718)4.99971573
39erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)4.93504433
40L-phenylalanine metabolic process (GO:0006558)4.93504433
41triglyceride homeostasis (GO:0070328)4.87737011
42acylglycerol homeostasis (GO:0055090)4.87737011
43regulation of bile acid biosynthetic process (GO:0070857)4.82157523
44cellular anion homeostasis (GO:0030002)4.73377781
45imidazole-containing compound metabolic process (GO:0052803)4.72497028
46positive regulation of T-helper cell differentiation (GO:0045624)4.72134058
47detection of bacterium (GO:0016045)4.64776533
48positive regulation of interleukin-1 secretion (GO:0050716)4.64372111
49regulation of interleukin-1 beta secretion (GO:0050706)4.62774475
50regulation of activation of Janus kinase activity (GO:0010533)4.54016492
51regulation of plasminogen activation (GO:0010755)4.52607234
52detection of other organism (GO:0098543)4.50883638
53regulation of heterotypic cell-cell adhesion (GO:0034114)4.49401535
54cholesterol homeostasis (GO:0042632)4.49105392
55sterol transport (GO:0015918)4.44804999
56cholesterol transport (GO:0030301)4.44804999
57sterol homeostasis (GO:0055092)4.42745962
58positive regulation of steroid metabolic process (GO:0045940)4.39993253
59positive regulation of neutrophil chemotaxis (GO:0090023)4.37148736
60positive regulation of neutrophil migration (GO:1902624)4.37148736
61dendritic cell migration (GO:0036336)4.36934447
62regulation of cytokine secretion involved in immune response (GO:0002739)4.36781907
63negative regulation of protein activation cascade (GO:2000258)4.34119297
64fibrinolysis (GO:0042730)4.31659686
65phospholipid homeostasis (GO:0055091)4.27696379
66lipoprotein metabolic process (GO:0042157)4.24123026
67positive regulation of glycoprotein biosynthetic process (GO:0010560)4.23473478
68trivalent inorganic anion homeostasis (GO:0072506)4.22363358
69phosphate ion homeostasis (GO:0055062)4.22363358
70proline metabolic process (GO:0006560)4.15648683
71complement activation, alternative pathway (GO:0006957)4.13752296
72muscle atrophy (GO:0014889)4.12606667
73positive regulation of triglyceride lipase activity (GO:0061365)4.11092405
74positive regulation of lipoprotein lipase activity (GO:0051006)4.11092405
75response to nitric oxide (GO:0071731)4.07645576
76striated muscle atrophy (GO:0014891)4.07014561
77superoxide anion generation (GO:0042554)4.06357407
78regulation of interleukin-1 secretion (GO:0050704)4.02379002
79negative regulation of hemostasis (GO:1900047)4.00661295
80negative regulation of blood coagulation (GO:0030195)4.00661295
81synapsis (GO:0007129)3.98003390
82peptide catabolic process (GO:0043171)3.96832675
83regulation of triglyceride catabolic process (GO:0010896)3.94609427
84regulation of T-helper 1 type immune response (GO:0002825)3.92879512
85single strand break repair (GO:0000012)3.89989527
86regulation of cholesterol homeostasis (GO:2000188)3.85200865
87positive regulation of NF-kappaB import into nucleus (GO:0042346)3.81074333
88fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540)3.80100369
89regulation of lipoprotein particle clearance (GO:0010984)3.76183115
90diacylglycerol metabolic process (GO:0046339)3.75640170
91bile acid metabolic process (GO:0008206)3.73684867
92positive regulation of interleukin-1 beta production (GO:0032731)3.73076726
93bile acid biosynthetic process (GO:0006699)3.72455896
94regulation of granulocyte chemotaxis (GO:0071622)3.68208022
95regulation of Cdc42 GTPase activity (GO:0043088)3.68097691
96regulation of neutrophil chemotaxis (GO:0090022)3.67724895
97regulation of neutrophil migration (GO:1902622)3.67724895
98negative regulation of coagulation (GO:0050819)3.67285487
99cellular glucuronidation (GO:0052695)3.62216872
100uronic acid metabolic process (GO:0006063)3.56065861
101glucuronate metabolic process (GO:0019585)3.56065861
102lipid homeostasis (GO:0055088)3.56010889
103cytokine secretion (GO:0050663)3.55872720
104glutamate metabolic process (GO:0006536)3.54863494
105negative regulation of wound healing (GO:0061045)3.53816510
106intestinal cholesterol absorption (GO:0030299)3.52155896
107regulation of apoptotic cell clearance (GO:2000425)3.50126189
108hydrogen peroxide biosynthetic process (GO:0050665)3.50102253
109regulation of humoral immune response (GO:0002920)3.49967838
110skeletal muscle adaptation (GO:0043501)3.49946420
111positive regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043372)3.42377750
112sulfate transport (GO:0008272)3.38671589
113epoxygenase P450 pathway (GO:0019373)3.37000630
114response to prostaglandin E (GO:0034695)3.36952152
115phospholipid efflux (GO:0033700)3.36537398
116positive regulation of interleukin-1 production (GO:0032732)3.36503990
117regulation of hexokinase activity (GO:1903299)3.36481827
118regulation of glucokinase activity (GO:0033131)3.36481827
119protein activation cascade (GO:0072376)3.36117398
120positive regulation of blood coagulation (GO:0030194)3.33990224
121positive regulation of hemostasis (GO:1900048)3.33990224
122positive regulation of fatty acid biosynthetic process (GO:0045723)3.30995058
123detection of external biotic stimulus (GO:0098581)3.29209737
124nitrogen cycle metabolic process (GO:0071941)3.27572030
125energy homeostasis (GO:0097009)3.27395633
126detection of biotic stimulus (GO:0009595)3.26998260
127regulation of T-helper cell differentiation (GO:0045622)3.26751775
128regulation of systemic arterial blood pressure by renin-angiotensin (GO:0003081)3.22558969
129lipoxygenase pathway (GO:0019372)3.22259837
130positive regulation of lipid catabolic process (GO:0050996)3.20338025
131regulation of cholesterol transport (GO:0032374)3.20311921
132regulation of sterol transport (GO:0032371)3.20311921
133serine family amino acid catabolic process (GO:0009071)3.19802211
134positive regulation of granulocyte macrophage colony-stimulating factor production (GO:0032725)3.19388851
135positive regulation of T cell mediated cytotoxicity (GO:0001916)3.18468647
136positive regulation of glycoprotein metabolic process (GO:1903020)3.18055901
137acute-phase response (GO:0006953)3.15604799
138L-ascorbic acid metabolic process (GO:0019852)3.14677689
139regulation of granulocyte macrophage colony-stimulating factor production (GO:0032645)3.14245375
140positive regulation of coagulation (GO:0050820)3.13980715
141ethanol oxidation (GO:0006069)3.12710643
142negative regulation of muscle hypertrophy (GO:0014741)3.11727400
143heme transport (GO:0015886)3.11529579
144neutral lipid catabolic process (GO:0046461)3.11215990
145acylglycerol catabolic process (GO:0046464)3.11215990
146positive regulation of prostaglandin secretion (GO:0032308)3.09220234
147positive regulation of heat generation (GO:0031652)3.07531802
148drug transmembrane transport (GO:0006855)3.07360534
149positive regulation of icosanoid secretion (GO:0032305)3.07265042
150glycine metabolic process (GO:0006544)3.06357382
151positive regulation of cholesterol efflux (GO:0010875)3.06150641
152regulation of helicase activity (GO:0051095)3.05950074
153positive regulation of interleukin-12 production (GO:0032735)3.04746440
154aromatic amino acid family catabolic process (GO:0009074)3.04158084
155reactive oxygen species biosynthetic process (GO:1903409)3.04132253
156negative regulation of lipid transport (GO:0032369)3.02653803
157response to pheromone (GO:0019236)3.00647228
158bundle of His cell to Purkinje myocyte communication (GO:0086069)3.00452207
159polyketide metabolic process (GO:0030638)2.99113733
160doxorubicin metabolic process (GO:0044598)2.99113733
161daunorubicin metabolic process (GO:0044597)2.99113733
162regulation of MHC class II biosynthetic process (GO:0045346)2.98681552
163intestinal absorption (GO:0050892)2.98625931
164regulation of acrosome reaction (GO:0060046)2.98242900
165NIK/NF-kappaB signaling (GO:0038061)2.96659722
166angiotensin maturation (GO:0002003)2.95360043
167response to prostaglandin (GO:0034694)2.94175107
168leukocyte tethering or rolling (GO:0050901)2.94129127
169dendritic cell differentiation (GO:0097028)2.93748616
170urea metabolic process (GO:0019627)2.92736417
171urea cycle (GO:0000050)2.92736417
172positive regulation of cellular amine metabolic process (GO:0033240)2.91232095
173positive regulation of CD4-positive, alpha-beta T cell activation (GO:2000516)2.90835520
174lipoprotein transport (GO:0042953)2.90566686
175NAD biosynthetic process (GO:0009435)2.88707939
176ovulation from ovarian follicle (GO:0001542)2.88053846
177cellular response to ATP (GO:0071318)2.86139801
178renal absorption (GO:0070293)2.80781574
179negative regulation of fatty acid biosynthetic process (GO:0045717)2.74893891
180cellular protein complex localization (GO:0034629)2.72217956
181anion homeostasis (GO:0055081)2.72205908
182positive regulation of sterol transport (GO:0032373)2.70747804
183positive regulation of cholesterol transport (GO:0032376)2.70747804
184disruption of cells of other organism involved in symbiotic interaction (GO:0051818)2.70516030
185killing of cells in other organism involved in symbiotic interaction (GO:0051883)2.70516030
186regulation of fever generation (GO:0031620)2.68621891
187positive regulation of leukocyte migration (GO:0002687)2.67566423
188detection of chemical stimulus involved in sensory perception of bitter taste (GO:0001580)2.66564951
189nitric oxide biosynthetic process (GO:0006809)2.65202971
190negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class 2.64510197
191positive regulation of monocyte chemotaxis (GO:0090026)2.57022470
192DNA strand renaturation (GO:0000733)2.56310062

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1RXR_22158963_ChIP-Seq_LIVER_Mouse5.87759167
2LXR_22158963_ChIP-Seq_LIVER_Mouse4.82024013
3PPARA_22158963_ChIP-Seq_LIVER_Mouse4.80144561
4HNF4A_19761587_ChIP-ChIP_CACO-2_Human3.80602651
5CEBPA_23403033_ChIP-Seq_LIVER_Mouse3.79857164
6* FOXA2_19822575_ChIP-Seq_HepG2_Human3.79112886
7NR1I2_20693526_ChIP-Seq_LIVER_Mouse3.27239989
8TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse3.19320820
9* HNF4A_19822575_ChIP-Seq_HepG2_Human3.11919930
10E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse3.00440180
11CEBPB_23403033_ChIP-Seq_LIVER_Mouse2.95548232
12PCGF2_27294783_Chip-Seq_ESCs_Mouse2.93260330
13CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human2.77653174
14FLI1_27457419_Chip-Seq_LIVER_Mouse2.69836750
15GBX2_23144817_ChIP-Seq_PC3_Human2.69471585
16TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.68507754
17PPARG_19300518_ChIP-PET_3T3-L1_Mouse2.65392455
18EZH2_22144423_ChIP-Seq_EOC_Human2.58696735
19ESR1_15608294_ChIP-ChIP_MCF-7_Human2.57322479
20SUZ12_27294783_Chip-Seq_NPCs_Mouse2.48221842
21NFE2_27457419_Chip-Seq_LIVER_Mouse2.29551177
22PRDM5_23873026_ChIP-Seq_MEFs_Mouse2.29514612
23PCGF2_27294783_Chip-Seq_NPCs_Mouse2.19371839
24ZFP57_27257070_Chip-Seq_ESCs_Mouse2.17589949
25IRF8_22096565_ChIP-ChIP_GC-B_Human2.17154578
26* EGR1_23403033_ChIP-Seq_LIVER_Mouse2.01969160
27VDR_22108803_ChIP-Seq_LS180_Human2.01936314
28BP1_19119308_ChIP-ChIP_Hs578T_Human2.00272080
29ESR1_17901129_ChIP-ChIP_LIVER_Mouse10.4338997
30HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.95723940
31GATA4_25053715_ChIP-Seq_YYC3_Human1.94105462
32IRF8_21731497_ChIP-ChIP_J774_Mouse1.89142975
33AR_21909140_ChIP-Seq_LNCAP_Human1.85492672
34DROSHA_22980978_ChIP-Seq_HELA_Human1.85031135
35EZH2_27294783_Chip-Seq_NPCs_Mouse1.81589494
36EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.76753980
37SMAD_19615063_ChIP-ChIP_OVARY_Human1.75069787
38VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.72143821
39IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.71184941
40P53_22387025_ChIP-Seq_ESCs_Mouse1.70978269
41TCF7L2_21901280_ChIP-Seq_H4IIE_Rat1.68865334
42SUZ12_18555785_Chip-Seq_ESCs_Mouse1.66342919
43NANOG_18555785_Chip-Seq_ESCs_Mouse1.65434662
44GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.65191747
45SALL4_18804426_ChIP-ChIP_XEN_Mouse1.64389257
46EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.62443436
47OCT4_18555785_Chip-Seq_ESCs_Mouse1.62130730
48CDX2_19796622_ChIP-Seq_MESCs_Mouse1.61677600
49TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.61635770
50FOXO3_23340844_ChIP-Seq_DLD1_Human1.59462779
51RUNX1_27457419_Chip-Seq_LIVER_Mouse1.58368584
52NMYC_18555785_Chip-Seq_ESCs_Mouse1.55690988
53CMYC_18555785_Chip-Seq_ESCs_Mouse1.55322072
54FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.55303447
55TCF4_18268006_ChIP-ChIP_LS174T_Human1.54936789
56E2F1_18555785_Chip-Seq_ESCs_Mouse1.54865732
57CDX2_20551321_ChIP-Seq_CACO-2_Human1.53872594
58STAT3_18555785_Chip-Seq_ESCs_Mouse1.53401106
59RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.52819461
60ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.52218656
61P300_18555785_Chip-Seq_ESCs_Mouse1.52204066
62EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.50625235
63ESRRB_18555785_Chip-Seq_ESCs_Mouse1.49482243
64SOX2_18555785_Chip-Seq_ESCs_Mouse1.48877991
65BMI1_23680149_ChIP-Seq_NPCS_Mouse1.48281436
66* GATA6_25053715_ChIP-Seq_YYC3_Human1.46657831
67ZFX_18555785_Chip-Seq_ESCs_Mouse1.45721788
68OCT4_21477851_ChIP-Seq_ESCs_Mouse1.44254622
69Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.43946201
70PU1_27457419_Chip-Seq_LIVER_Mouse1.42135935
71CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.40802521
72P300_19829295_ChIP-Seq_ESCs_Human1.40522808
73PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.40165536
74KLF4_18555785_Chip-Seq_ESCs_Mouse1.40041866
75CTCF_18555785_Chip-Seq_ESCs_Mouse1.39115356
76* KAP1_22055183_ChIP-Seq_ESCs_Mouse1.38511632
77IGF1R_20145208_ChIP-Seq_DFB_Human1.37224026
78FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human1.35283557
79SMAD1_18555785_Chip-Seq_ESCs_Mouse1.34983444
80TP63_17297297_ChIP-ChIP_HaCaT_Human1.33793938
81SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse1.33031879
82CRX_20693478_ChIP-Seq_RETINA_Mouse1.32612632
83* IRF8_27001747_Chip-Seq_BMDM_Mouse1.31353095
84SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.29434769
85PIAS1_25552417_ChIP-Seq_VCAP_Human1.28859758
86GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.26170159
87KDM2B_26808549_Chip-Seq_REH_Human1.22842927
88AR_25329375_ChIP-Seq_VCAP_Human1.21615973
89TAL1_26923725_Chip-Seq_HPCs_Mouse1.21497853
90STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.19266607
91SOX2_27498859_Chip-Seq_STOMACH_Mouse1.18245823
92STAT1_17558387_ChIP-Seq_HELA_Human1.16661079
93ESR2_21235772_ChIP-Seq_MCF-7_Human1.16621956
94TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.14154335
95HTT_18923047_ChIP-ChIP_STHdh_Human1.14060180
96STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.13538602
97SMAD3_21741376_ChIP-Seq_EPCs_Human1.12558175
98CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.11744979
99KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.10570583
100KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.10570583
101KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.10570583
102SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.10424127
103RXRA_24833708_ChIP-Seq_LIVER_Mouse1.10412547
104TP53_16413492_ChIP-PET_HCT116_Human1.09921932
105CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.09583956
106TP53_18474530_ChIP-ChIP_U2OS_Human1.08170122
107CLOCK_20551151_ChIP-Seq_293T_Human1.06379020
108CDX2_22108803_ChIP-Seq_LS180_Human1.06139175
109TRIM28_21343339_ChIP-Seq_HEK293_Human1.05478645
110IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.05353931
111STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.05280958
112ER_23166858_ChIP-Seq_MCF-7_Human1.04838172
113SMAD4_21799915_ChIP-Seq_A2780_Human1.03868687
114GATA1_22025678_ChIP-Seq_K562_Human1.03507230
115LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.02460884
116SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.01980505
117NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.01731943
118FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.01643037
119CBX2_27304074_Chip-Seq_ESCs_Mouse1.00781462
120AHR_22903824_ChIP-Seq_MCF-7_Human1.00521857
121PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.00337373
122SUZ12_18692474_ChIP-Seq_MEFs_Mouse0.99469341
123SOX2_20726797_ChIP-Seq_SW620_Human0.99248675
124SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.97408182
125EED_16625203_ChIP-ChIP_MESCs_Mouse0.96830235
126PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse0.96501310
127POU3F2_20337985_ChIP-ChIP_501MEL_Human0.96312333
128* TCF4_23295773_ChIP-Seq_U87_Human0.95899674
129SUZ12_16625203_ChIP-ChIP_MESCs_Mouse0.95676772
130JARID2_20075857_ChIP-Seq_MESCs_Mouse0.95657513
131AR_21915096_ChIP-Seq_LNCaP-1F5_Human0.95200579
132SREBP1_19666523_ChIP-Seq_LIVER_Mouse0.95013177
133VDR_24787735_ChIP-Seq_THP-1_Human0.94273194
134NR3C1_21868756_ChIP-Seq_MCF10A_Human0.93116914
135AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.92956266
136* STAT3_23295773_ChIP-Seq_U87_Human0.92624986
137ZNF652_21678463_ChIP-ChIP_ZR75-1_Human0.92202944
138ZNF263_19887448_ChIP-Seq_K562_Human0.92169760
139ESR1_20079471_ChIP-ChIP_T-47D_Human0.91335188
140TCF4_22108803_ChIP-Seq_LS180_Human0.90113936
141BCAT_22108803_ChIP-Seq_LS180_Human0.89776594
142FOXM1_26456572_ChIP-Seq_MCF-7_Human0.89042752
143RCOR2_21632747_ChIP-Seq_MESCs_Mouse0.88920393
144ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.88813118
145EZH2_18974828_ChIP-Seq_MESCs_Mouse0.88268567
146THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse0.84585359
147FOXA1_25552417_ChIP-Seq_VCAP_Human0.84013819
148ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.81880817
149GATA3_24758297_ChIP-Seq_MCF-7_Human0.81833417
150CEBPB_22108803_ChIP-Seq_LS180_Human0.80417075
151HIF1A_21447827_ChIP-Seq_MCF-7_Human0.79799043
152PPAR_26484153_Chip-Seq_NCI-H1993_Human0.79661127
153FOXH1_21741376_ChIP-Seq_EPCs_Human0.76760455
154EP300_21415370_ChIP-Seq_HL-1_Mouse0.73890538
155STAT3_19079543_ChIP-ChIP_MESCs_Mouse0.72988800
156CTNNB1_20460455_ChIP-Seq_HCT116_Human0.71366737
157GATA3_20176728_ChIP-ChIP_TSCs_Mouse0.70931420
158ESR1_21235772_ChIP-Seq_MCF-7_Human0.70757494
159SMAD3_21741376_ChIP-Seq_HESCs_Human0.70687058
160POU5F1_18700969_ChIP-ChIP_MESCs_Mouse0.70055248
161SOX9_24532713_ChIP-Seq_HFSC_Mouse0.68615331
162EOMES_21245162_ChIP-Seq_HESCs_Human0.66473253
163SOX2_21211035_ChIP-Seq_LN229_Human0.65986510
164NANOG_19829295_ChIP-Seq_ESCs_Human0.65414312
165SOX2_19829295_ChIP-Seq_ESCs_Human0.65414312
166OCT4_20526341_ChIP-Seq_ESCs_Human0.65301594
167SMAD4_21741376_ChIP-Seq_HESCs_Human0.65046536
168SREBP2_21459322_ChIP-Seq_LIVER_Mouse0.64533563
169ZNF217_24962896_ChIP-Seq_MCF-7_Human0.63030018
170NANOG_20526341_ChIP-Seq_ESCs_Human0.62255268
171SMAD1_18555785_ChIP-Seq_MESCs_Mouse0.61325492
172PPARD_23208498_ChIP-Seq_MDA-MB-231_Human0.61021568
173SOX17_20123909_ChIP-Seq_XEN_Mouse0.59663207
174NR0B1_18358816_ChIP-ChIP_MESCs_Mouse0.59576362
175SMAD4_21741376_ChIP-Seq_EPCs_Human0.59056840
176POU5F1_16518401_ChIP-PET_MESCs_Mouse0.59017369
177AR_20517297_ChIP-Seq_VCAP_Human0.58236612
178RXR_22108803_ChIP-Seq_LS180_Human0.58007426
179RAD21_21589869_ChIP-Seq_MESCs_Mouse0.57961080
180P63_20808887_ChIP-Seq_KERATINOCYTES_Human0.56968555
181NFIB_24661679_ChIP-Seq_LUNG_Mouse0.56708530
182JARID1B-DAIN_22020125_ChIP-Seq_ESCs_Mouse0.56244842

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002254_reproductive_system_inflammat7.07958487
2MP0002876_abnormal_thyroid_physiology5.12209242
3MP0000685_abnormal_immune_system3.93441208
4MP0005647_abnormal_sex_gland3.75027704
5MP0001346_abnormal_lacrimal_gland3.61652254
6MP0003183_abnormal_peptide_metabolism3.50529942
7MP0003122_maternal_imprinting3.08332593
8MP0008057_abnormal_DNA_replication3.07549532
9MP0009697_abnormal_copulation3.05865445
10MP0003718_maternal_effect3.01069185
11MP0001835_abnormal_antigen_presentation2.95795368
12MP0005645_abnormal_hypothalamus_physiol2.83224719
13MP0006082_CNS_inflammation2.75121741
14MP0005360_urolithiasis2.60394315
15MP0001873_stomach_inflammation2.53983539
16MP0005310_abnormal_salivary_gland2.32190931
17MP0002277_abnormal_respiratory_mucosa2.28280717
18MP0001348_abnormal_lacrimal_gland2.27253968
19MP0002160_abnormal_reproductive_system2.18318531
20MP0005408_hypopigmentation2.15539842
21MP0003195_calcinosis2.02349125
22MP0002148_abnormal_hypersensitivity_rea1.84223278
23MP0002138_abnormal_hepatobiliary_system1.84170918
24MP0009785_altered_susceptibility_to1.76794704
25MP0003890_abnormal_embryonic-extraembry1.69842042
26MP0003123_paternal_imprinting1.68463005
27MP0005671_abnormal_response_to1.66653038
28MP0005085_abnormal_gallbladder_physiolo1.60273000
29MP0005503_abnormal_tendon_morphology1.60049353
30MP0004782_abnormal_surfactant_physiolog1.59943632
31MP0002735_abnormal_chemical_nociception1.58995621
32MP0009764_decreased_sensitivity_to1.58506039
33MP0001666_abnormal_nutrient_absorption1.56403727
34MP0004510_myositis1.54733690
35MP0005377_hearing/vestibular/ear_phenot1.52455615
36MP0003878_abnormal_ear_physiology1.52455615
37MP0005451_abnormal_body_composition1.47995713
38MP0005025_abnormal_response_to1.47438701
39MP0003879_abnormal_hair_cell1.46933467
40MP0008004_abnormal_stomach_pH1.46825445
41MP0005395_other_phenotype1.44450468
42MP0000609_abnormal_liver_physiology1.41692449
43MP0003763_abnormal_thymus_physiology1.35122805
44MP0003724_increased_susceptibility_to1.31863887
45MP0001881_abnormal_mammary_gland1.26830379
46MP0009333_abnormal_splenocyte_physiolog1.26614545
47MP0000566_synostosis1.26527601
48MP0001501_abnormal_sleep_pattern1.26424195
49MP0005389_reproductive_system_phenotype1.25866513
50MP0000604_amyloidosis1.24799978
51MP0002139_abnormal_hepatobiliary_system1.24149664
52MP0003950_abnormal_plasma_membrane1.23868348
53MP0005365_abnormal_bile_salt1.23641550
54MP0003941_abnormal_skin_development1.22588469
55MP0005448_abnormal_energy_balance1.21236028
56MP0002419_abnormal_innate_immunity1.18961909
57MP0001915_intracranial_hemorrhage1.18483827
58MP0003252_abnormal_bile_duct1.17990095
59MP0002132_abnormal_respiratory_system1.17032356
60MP0004019_abnormal_vitamin_homeostasis1.15562137
61MP0003121_genomic_imprinting1.15198885
62MP0005000_abnormal_immune_tolerance1.12536746
63MP0005058_abnormal_lysosome_morphology1.11667187
64MP0010368_abnormal_lymphatic_system1.09500366
65MP0003699_abnormal_female_reproductive1.08539119
66MP0001790_abnormal_immune_system1.07921216
67MP0005387_immune_system_phenotype1.07921216
68MP0010030_abnormal_orbit_morphology1.07548962
69MP0010234_abnormal_vibrissa_follicle1.05962195
70MP0006292_abnormal_olfactory_placode1.04622737
71MP0001800_abnormal_humoral_immune1.04282032
72MP0000538_abnormal_urinary_bladder1.03802446
73MP0005409_darkened_coat_color1.03154384
74MP0008875_abnormal_xenobiotic_pharmacok1.01934596
75MP0002796_impaired_skin_barrier1.00716972
76MP0005464_abnormal_platelet_physiology1.00714090
77MP0005636_abnormal_mineral_homeostasis0.99967369
78MP0003045_fibrosis0.99764268
79MP0004272_abnormal_basement_membrane0.99705765
80MP0001845_abnormal_inflammatory_respons0.98640965
81MP0010329_abnormal_lipoprotein_level0.98593626
82MP0010386_abnormal_urinary_bladder0.98117724
83MP0003191_abnormal_cellular_cholesterol0.97735996
84MP0001764_abnormal_homeostasis0.95746584
85MP0002723_abnormal_immune_serum0.95265910
86MP0010155_abnormal_intestine_physiology0.92541407
87MP0005334_abnormal_fat_pad0.92023156
88MP0002452_abnormal_antigen_presenting0.91223127
89MP0003567_abnormal_fetal_cardiomyocyte0.90691870
90MP0009765_abnormal_xenobiotic_induced0.88802167
91MP0002971_abnormal_brown_adipose0.87820964
92MP0003959_abnormal_lean_body0.87437307
93MP0008469_abnormal_protein_level0.86797352
94MP0002405_respiratory_system_inflammati0.86661492
95MP0000598_abnormal_liver_morphology0.86479515
96MP0000639_abnormal_adrenal_gland0.86077553
97MP0003868_abnormal_feces_composition0.83712425
98MP0000470_abnormal_stomach_morphology0.82717176
99MP0003828_pulmonary_edema0.82669070
100MP0002089_abnormal_postnatal_growth/wei0.82573020
101MP0009780_abnormal_chondrocyte_physiolo0.81144451
102MP0001663_abnormal_digestive_system0.80910885
103MP0005319_abnormal_enzyme/_coenzyme0.79505624
104MP0009115_abnormal_fat_cell0.79444356
105MP0003638_abnormal_response/metabolism_0.78616432
106MP0000383_abnormal_hair_follicle0.78014085
107MP0005501_abnormal_skin_physiology0.76518856
108MP0009642_abnormal_blood_homeostasis0.75208241
109MP0004264_abnormal_extraembryonic_tissu0.74777655
110MP0001819_abnormal_immune_cell0.74273449
111MP0009840_abnormal_foam_cell0.74207262
112MP0000569_abnormal_digit_pigmentation0.74032952
113MP0005499_abnormal_olfactory_system0.72876033
114MP0005394_taste/olfaction_phenotype0.72876033
115MP0004947_skin_inflammation0.72565631
116MP0002938_white_spotting0.71511833
117MP0003453_abnormal_keratinocyte_physiol0.70733535
118MP0002420_abnormal_adaptive_immunity0.69199992
119MP0002998_abnormal_bone_remodeling0.68970316
120MP0005332_abnormal_amino_acid0.68875268
121MP0005023_abnormal_wound_healing0.67804798
122MP0000613_abnormal_salivary_gland0.67533184
123MP0008058_abnormal_DNA_repair0.67443895
124MP0008789_abnormal_olfactory_epithelium0.67145149
125MP0002090_abnormal_vision0.66486525
126MP0001324_abnormal_eye_pigmentation0.66370323
127MP0005410_abnormal_fertilization0.65910359
128MP0003172_abnormal_lysosome_physiology0.64852948
129MP0001986_abnormal_taste_sensitivity0.64721675
130MP0003315_abnormal_perineum_morphology0.64172090
131MP0009643_abnormal_urine_homeostasis0.63835657
132MP0002161_abnormal_fertility/fecundity0.62942681
133MP0002136_abnormal_kidney_physiology0.61865972
134MP0002118_abnormal_lipid_homeostasis0.61269864
135MP0001485_abnormal_pinna_reflex0.59919125
136MP0002233_abnormal_nose_morphology0.59804448
137MP0001730_embryonic_growth_arrest0.59438052
138MP0003806_abnormal_nucleotide_metabolis0.59051613
139MP0005670_abnormal_white_adipose0.58742149
140MP0005084_abnormal_gallbladder_morpholo0.58017727
141MP0003186_abnormal_redox_activity0.58011685
142MP0002098_abnormal_vibrissa_morphology0.57526733
143MP0009384_cardiac_valve_regurgitation0.56797172
144MP0001661_extended_life_span0.55665652
145MP0001929_abnormal_gametogenesis0.54341745
146MP0005551_abnormal_eye_electrophysiolog0.54319053
147MP0003329_amyloid_beta_deposits0.53670615
148MP0005376_homeostasis/metabolism_phenot0.52159201
149MP0005584_abnormal_enzyme/coenzyme_acti0.48557785
150MP0001756_abnormal_urination0.48141419
151MP0001119_abnormal_female_reproductive0.47400950
152MP0003011_delayed_dark_adaptation0.46127468
153MP0006054_spinal_hemorrhage0.46097065
154MP0003953_abnormal_hormone_level0.46081124
155MP0003119_abnormal_digestive_system0.43820076
156MP0002078_abnormal_glucose_homeostasis0.42755493
157MP0000653_abnormal_sex_gland0.41644324
158MP0001270_distended_abdomen0.39708198
159MP0005257_abnormal_intraocular_pressure0.38200596
160MP0001293_anophthalmia0.37949723
161MP0002909_abnormal_adrenal_gland0.36552086

Predicted human phenotypes

RankGene SetZ-score
1Deep venous thrombosis (HP:0002625)9.91885845
2Prolonged partial thromboplastin time (HP:0003645)7.41182728
3Spontaneous abortion (HP:0005268)6.56932664
4Abnormality of the common coagulation pathway (HP:0010990)6.24535784
5Joint hemorrhage (HP:0005261)5.83371187
6Abnormality of monocarboxylic acid metabolism (HP:0010996)5.81854206
7Hypolipoproteinemia (HP:0010981)5.48079117
8Eczematoid dermatitis (HP:0000976)5.42340018
9Intrahepatic cholestasis (HP:0001406)5.33120759
10Abnormality of aromatic amino acid family metabolism (HP:0004338)5.27233488
11Increased IgE level (HP:0003212)5.22509734
12Recurrent cutaneous fungal infections (HP:0011370)5.09721074
13Chronic mucocutaneous candidiasis (HP:0002728)5.09721074
14Xanthomatosis (HP:0000991)4.58612362
15Complement deficiency (HP:0004431)4.58054037
16Hypoalphalipoproteinemia (HP:0003233)4.42806657
17Abnormality of the level of lipoprotein cholesterol (HP:0010979)4.21758755
18Keratoconjunctivitis (HP:0001096)4.01955791
19Glomerulonephritis (HP:0000099)3.84104423
20Recurrent fungal infections (HP:0002841)3.68228487
21Hydroxyprolinuria (HP:0003080)3.68100464
22Abnormality of proline metabolism (HP:0010907)3.68100464
23Prostate neoplasm (HP:0100787)3.61599340
24Hypercholesterolemia (HP:0003124)3.57616411
25Acanthocytosis (HP:0001927)3.39462488
26Hypophosphatemic rickets (HP:0004912)3.35407225
27Recurrent abscess formation (HP:0002722)3.32492514
28Right ventricular cardiomyopathy (HP:0011663)3.31825231
29Broad alveolar ridges (HP:0000187)3.30590114
30Recurrent gram-negative bacterial infections (HP:0005420)3.28541752
31Abnormality of complement system (HP:0005339)3.28428378
32Amyloidosis (HP:0011034)3.23388787
33Abnormality of carpal bone ossification (HP:0006257)3.22576054
34Abnormality of glutamine family amino acid metabolism (HP:0010902)3.21948566
35Hyperlipoproteinemia (HP:0010980)3.20934801
36Cheilitis (HP:0100825)3.17218530
37Recurrent skin infections (HP:0001581)3.16441814
38Menorrhagia (HP:0000132)3.14956908
39Pustule (HP:0200039)3.11818619
40Gingivitis (HP:0000230)3.11471943
41Epidermoid cyst (HP:0200040)3.04340396
42Chromosomal breakage induced by crosslinking agents (HP:0003221)3.04150295
43Upper limb muscle weakness (HP:0003484)2.93840301
44Hemorrhage of the eye (HP:0011885)2.91699123
45Recurrent bacterial skin infections (HP:0005406)2.88018284
46Type I diabetes mellitus (HP:0100651)2.86845906
47Retinal atrophy (HP:0001105)2.83487371
48Abnormality of pyrimidine metabolism (HP:0004353)2.78479878
49Palmoplantar hyperkeratosis (HP:0000972)2.78129669
50Urticaria (HP:0001025)2.77271165
51Retrobulbar optic neuritis (HP:0100654)2.76168316
52Optic neuritis (HP:0100653)2.76168316
53Chromsome breakage (HP:0040012)2.75480723
54Orchitis (HP:0100796)2.74389764
55Poikilocytosis (HP:0004447)2.73771734
56Abnormality of calcium-phosphate metabolism (HP:0100530)2.72125184
57Conjugated hyperbilirubinemia (HP:0002908)2.71610431
58Thrombophlebitis (HP:0004418)2.71191316
59Steatorrhea (HP:0002570)2.71078393
60Palmar hyperkeratosis (HP:0010765)2.70594059
61Abnormal tarsal ossification (HP:0008369)2.69801128
62Respiratory insufficiency due to defective ciliary clearance (HP:0200073)2.69620612
63Generalized aminoaciduria (HP:0002909)2.66739148
64Congenital malformation of the right heart (HP:0011723)2.65528592
65Double outlet right ventricle (HP:0001719)2.65528592
66Hyperglycinemia (HP:0002154)2.65322310
67Plantar hyperkeratosis (HP:0007556)2.59545943
68Supernumerary spleens (HP:0009799)2.58727313
69Absent/shortened dynein arms (HP:0200106)2.58612206
70Dynein arm defect of respiratory motile cilia (HP:0012255)2.58612206
71Hepatoblastoma (HP:0002884)2.58430424
72Prolonged neonatal jaundice (HP:0006579)2.57777954
73Pancreatic islet-cell hyperplasia (HP:0004510)2.55771914
74Tongue fasciculations (HP:0001308)2.54283867
75Facial shape deformation (HP:0011334)2.52763896
76Potter facies (HP:0002009)2.52763896
77Hypoglycemic coma (HP:0001325)2.51373319
78Hypergammaglobulinemia (HP:0010702)2.51183227
79Febrile seizures (HP:0002373)2.50706665
80Abnormality of macrophages (HP:0004311)2.50186826
81Xerostomia (HP:0000217)2.48496297
82Recurrent pneumonia (HP:0006532)2.48046109
83Vascular calcification (HP:0004934)2.46456145
84Cholecystitis (HP:0001082)2.46150220
85Abnormal gallbladder physiology (HP:0012438)2.46150220
86Ileus (HP:0002595)2.45473593
87Rickets (HP:0002748)2.44813152
88Abnormal hand bone ossification (HP:0010660)2.42164667
89Septo-optic dysplasia (HP:0100842)2.42012265
90Mediastinal lymphadenopathy (HP:0100721)2.37360987
91Proximal tubulopathy (HP:0000114)2.35154626
92Osteomalacia (HP:0002749)2.34130501
93Abnormal delivery (HP:0001787)2.30409552
94Hyperglycemia (HP:0003074)2.29525625
95Renal cortical cysts (HP:0000803)2.28974390
96Abnormal ossification of hand bones (HP:0005921)2.27811118
97Tetraparesis (HP:0002273)2.27520124
98Gangrene (HP:0100758)2.26037090
99Alopecia of scalp (HP:0002293)2.25659532
100Aplasia cutis congenita (HP:0001057)2.24970919
101Type 2 muscle fiber atrophy (HP:0003554)2.24466106
102Chronic diarrhea (HP:0002028)2.24212811
103Premature loss of primary teeth (HP:0006323)2.22109901
104Flat acetabular roof (HP:0003180)2.18947526
105Obstructive lung disease (HP:0006536)2.16593087
106Chronic obstructive pulmonary disease (HP:0006510)2.16593087
107Confusion (HP:0001289)2.16516461
108Keratitis (HP:0000491)2.14903201
109Myositis (HP:0100614)2.13752265
110Periodontitis (HP:0000704)2.12552676
111Hyperammonemia (HP:0001987)2.10185353
112Abnormality of the nasal septum (HP:0000419)2.09613192
113Cardiovascular calcification (HP:0011915)2.09416906
114Abnormality of methionine metabolism (HP:0010901)2.08105039
115Bilateral sensorineural hearing impairment (HP:0008619)2.06560674
116Muscle fibrillation (HP:0010546)2.05972170
117Systemic lupus erythematosus (HP:0002725)2.05967072
118Enlarged kidneys (HP:0000105)2.05626438
119Lip pit (HP:0100267)2.04793473
120Symphalangism affecting the phalanges of the hand (HP:0009773)2.04572956
121Glycosuria (HP:0003076)2.03014050
122Abnormality of urine glucose concentration (HP:0011016)2.03014050
123Aplasia/Hypoplasia of the spleen (HP:0010451)2.02631778
124Asplenia (HP:0001746)2.00764974
125Joint swelling (HP:0001386)2.00112737
126Gingival bleeding (HP:0000225)1.99735523
127Nephritis (HP:0000123)1.99101362
128Increased IgM level (HP:0003496)1.98867939
129Abnormality of the gastric mucosa (HP:0004295)1.98613531
130Hypobetalipoproteinemia (HP:0003563)1.97907336
131Fair hair (HP:0002286)1.97512624
132Abnormality of the intrinsic pathway (HP:0010989)1.97179425
133Decreased central vision (HP:0007663)1.96088109
134Stomatitis (HP:0010280)1.95628194
135Aplasia/Hypoplasia of the fovea (HP:0008060)1.95202345
136Hypoplasia of the fovea (HP:0007750)1.95202345
137Autoimmune thrombocytopenia (HP:0001973)1.95096341
138Broad palm (HP:0001169)1.94703043
139Increased serum pyruvate (HP:0003542)1.94538072
140Prenatal maternal abnormality (HP:0002686)1.94494159
141Recurrent lower respiratory tract infections (HP:0002783)1.93299466
142Abnormality of the middle phalanx of the 5th finger (HP:0004219)1.92570989
143Abnormality of the renal cortex (HP:0011035)1.92095111
144Nausea (HP:0002018)1.91927564
145Abnormality of the alveolar ridges (HP:0006477)1.91309935
146Malnutrition (HP:0004395)1.91172439
147Hepatocellular carcinoma (HP:0001402)1.91067661
148Pigmentary retinal degeneration (HP:0001146)1.88889296
149Supernumerary nipples (HP:0002558)1.88314283
150Abnormal delayed hypersensitivity skin test (HP:0002963)1.87536848
151Abnormality of eosinophils (HP:0001879)1.87346485
152Unilateral renal agenesis (HP:0000122)1.87254796
153Myocardial infarction (HP:0001658)1.86803817
154Abnormality of aspartate family amino acid metabolism (HP:0010899)1.85807315
155Widely patent fontanelles and sutures (HP:0004492)1.85249852
156Abnormality of serine family amino acid metabolism (HP:0010894)1.85206368
157Abnormality of glycine metabolism (HP:0010895)1.85206368
158Elevated alkaline phosphatase (HP:0003155)1.84674426
159Abnormality of alkaline phosphatase activity (HP:0004379)1.84199825
160Fat malabsorption (HP:0002630)1.82422135
161Flared iliac wings (HP:0002869)1.82025215
162Abnormality of the preputium (HP:0100587)1.81987863
163Mitral stenosis (HP:0001718)1.81986286
164Papillary thyroid carcinoma (HP:0002895)1.81490234
165Thick nail (HP:0001805)1.81306368
166Reduced antithrombin III activity (HP:0001976)1.80758224
167Congenital sensorineural hearing impairment (HP:0008527)1.80695460
168Dehydration (HP:0001944)1.79836900
169Clubbing of toes (HP:0100760)1.77450581
170Abnormal enzyme/coenzyme activity (HP:0012379)1.77185555
171Respiratory distress (HP:0002098)1.76265222
172Purpura (HP:0000979)1.75935221
173Abnormality of serum amino acid levels (HP:0003112)1.73883607
174Neonatal death (HP:0003811)1.73777427
175Metaphyseal irregularity (HP:0003025)1.73712248
176Facial hemangioma (HP:0000329)1.73178940
177Abnormal urine phosphate concentration (HP:0012599)1.69455850
178Vacuolated lymphocytes (HP:0001922)1.67883778
179Delayed CNS myelination (HP:0002188)1.66813795
180Diastasis recti (HP:0001540)1.66745055
181Alacrima (HP:0000522)1.62389635
182Abnormal foot bone ossification (HP:0010675)1.61987368
183Megaloblastic anemia (HP:0001889)1.60533703
184Chronic hepatic failure (HP:0100626)1.60266397

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PDK25.79321011
2MAP3K144.58864048
3EPHA23.57296190
4DYRK33.46583316
5IRAK43.07279054
6PBK3.04536776
7TXK2.93672763
8INSRR2.87671206
9CDK122.83558964
10MAP3K92.81761149
11WNK42.78449590
12BMPR22.71546941
13CASK2.69883493
14IRAK32.65699660
15SIK32.63807216
16MAP2K72.52177872
17ARAF2.35557246
18ICK2.26979545
19TYRO32.26822885
20EPHA32.26281142
21FGFR12.02210060
22AKT31.98094698
23ERBB31.96020258
24PINK11.81188062
25FGFR21.79530067
26DYRK1B1.76054515
27NEK61.69155571
28RIPK11.64826055
29PRPF4B1.64813189
30LATS11.62409397
31NEK91.61056990
32NME11.60560496
33TNIK1.58861239
34IKBKE1.57735861
35PDPK11.55073842
36MAP3K131.54556516
37ZAK1.54074444
38EIF2AK21.53358503
39PIK3CA1.52741378
40MET1.49654382
41STK38L1.48695140
42TEC1.43758590
43TNK21.41355876
44NLK1.39374604
45PKN11.39356618
46EIF2AK31.38312950
47CDK91.36793628
48CDK71.35926986
49TYK21.35162423
50PDGFRA1.33927110
51FRK1.27834288
52WNK11.26537940
53FGFR41.25930422
54PDK11.20204745
55JAK11.19448985
56BMPR1B1.19072407
57KSR21.16229618
58MAP3K61.14575592
59MST41.12607403
60STK391.11729895
61IKBKB1.10583046
62TTK1.10278200
63CHUK1.10136834
64MAPKAPK31.09142919
65BRAF1.07598236
66BMX1.07391469
67BLK1.06793514
68ADRBK21.01172213
69MARK30.99798447
70CDK30.98347011
71PRKCI0.97571558
72ACVR1B0.95941569
73SYK0.95436217
74MELK0.94311877
75JAK30.92409358
76EEF2K0.92288036
77TESK20.90052577
78MAP3K120.89225694
79CSNK1D0.86836294
80CSNK1E0.86775313
81PRKCE0.86620565
82DYRK1A0.86441887
83BCR0.85389768
84YES10.83976498
85EPHA40.83424111
86EPHB10.82998153
87MAP3K30.80197607
88LATS20.79746742
89PLK20.78700252
90CAMK10.76728388
91RET0.76572727
92NTRK30.76293776
93PRKACG0.73406454
94PRKCD0.72470275
95TAOK30.71967729
96SGK20.71652228
97SGK2230.71158090
98SGK4940.71158090
99IRAK10.71139253
100PIM20.71014664
101STK30.70440525
102EIF2AK10.69773996
103MAP3K20.66249651
104TBK10.64468170
105NTRK20.64252495
106PTK20.62774097
107BRSK10.61830205
108PRKCQ0.61543432
109AURKA0.61372091
110RAF10.60777972
111MAPK150.60687613
112BTK0.60661889
113GRK10.60481808
114PRKACB0.59228845
115MST1R0.58707818
116PRKCZ0.57965326
117MYLK0.57427495
118MKNK20.56593024
119ERBB20.55914310
120SIK20.55856321
121CAMK1D0.54867366
122ITK0.53512341
123MATK0.52420681
124PRKAA10.52021440
125CDC42BPA0.51814111
126MTOR0.51580978
127PRKG20.51097367
128MAP3K50.50690398
129PKN20.50520908
130JAK20.49875046
131CSNK2A20.48669932
132TRIB30.48429533
133SGK10.47880356
134FGR0.42843781
135PLK40.41523550
136RIPK40.41097041
137PIK3CG0.40444169
138FGFR30.38507053
139LYN0.38499840
140CSNK2A10.36772320
141IGF1R0.36579828
142HCK0.36516453
143ERBB40.36432050
144MAP2K60.36100683
145GRK60.35947890
146CAMK2G0.35480223
147PRKACA0.34338518
148CDK20.33740203
149NUAK10.33374484
150CDK80.32504894
151BRSK20.32497252
152PLK10.32315451
153NEK10.32265170
154CSNK1A10.31157646
155DYRK20.31024312
156BRD40.30776480
157ERN10.29316154
158DDR20.29083873
159STK240.28790353
160LMTK20.27604779
161PRKCA0.27488645
162MAP4K10.27144020
163TRPM70.26743308
164PRKCG0.25773837
165CSK0.25377560
166SGK30.24960482
167PRKAA20.24916847
168MAPK110.24765949
169RPS6KB10.23134829
170KIT0.22757342
171SCYL20.20814010
172PRKG10.20688939

Predicted pathways (KEGG)

RankGene SetZ-score
1Histidine metabolism_Homo sapiens_hsa003404.00973081
2Vitamin digestion and absorption_Homo sapiens_hsa049773.76756490
3Intestinal immune network for IgA production_Homo sapiens_hsa046723.37125719
4alpha-Linolenic acid metabolism_Homo sapiens_hsa005922.77906284
5Glycine, serine and threonine metabolism_Homo sapiens_hsa002602.76523080
6Linoleic acid metabolism_Homo sapiens_hsa005912.67150575
7Fat digestion and absorption_Homo sapiens_hsa049752.62023987
8Caffeine metabolism_Homo sapiens_hsa002322.46768413
9Taurine and hypotaurine metabolism_Homo sapiens_hsa004302.41027757
10Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007602.39956932
11Fatty acid degradation_Homo sapiens_hsa000712.10221211
12Arachidonic acid metabolism_Homo sapiens_hsa005902.08683359
13Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006032.03571758
14NF-kappa B signaling pathway_Homo sapiens_hsa040641.97067482
15Steroid biosynthesis_Homo sapiens_hsa001001.96966801
16Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.93074937
17Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.89984977
182-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.87177549
19Maturity onset diabetes of the young_Homo sapiens_hsa049501.84942135
20Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.79585262
21Primary immunodeficiency_Homo sapiens_hsa053401.78242951
22ABC transporters_Homo sapiens_hsa020101.76668536
23Staphylococcus aureus infection_Homo sapiens_hsa051501.71594099
24Arginine biosynthesis_Homo sapiens_hsa002201.68517632
25Sphingolipid metabolism_Homo sapiens_hsa006001.68422880
26Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.64866620
27Cyanoamino acid metabolism_Homo sapiens_hsa004601.64370309
28Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.64333284
29Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.63450023
30Graft-versus-host disease_Homo sapiens_hsa053321.62320309
31Asthma_Homo sapiens_hsa053101.61978293
32Starch and sucrose metabolism_Homo sapiens_hsa005001.55779044
33Steroid hormone biosynthesis_Homo sapiens_hsa001401.53070700
34Butanoate metabolism_Homo sapiens_hsa006501.52115228
35Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.50039465
36Mineral absorption_Homo sapiens_hsa049781.49999540
37Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.48303746
38Ether lipid metabolism_Homo sapiens_hsa005651.46773779
39Fatty acid metabolism_Homo sapiens_hsa012121.44298696
40Allograft rejection_Homo sapiens_hsa053301.43260893
41Renin-angiotensin system_Homo sapiens_hsa046141.43144250
42Fatty acid elongation_Homo sapiens_hsa000621.40532909
43Rheumatoid arthritis_Homo sapiens_hsa053231.35150359
44RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.31841273
45Pyruvate metabolism_Homo sapiens_hsa006201.31311101
46Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.30247129
47Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.29517337
48Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.27294641
49Phenylalanine metabolism_Homo sapiens_hsa003601.27148631
50Propanoate metabolism_Homo sapiens_hsa006401.25101388
51beta-Alanine metabolism_Homo sapiens_hsa004101.17474871
52Legionellosis_Homo sapiens_hsa051341.16501023
53Galactose metabolism_Homo sapiens_hsa000521.15596805
54Leishmaniasis_Homo sapiens_hsa051401.13767614
55Arginine and proline metabolism_Homo sapiens_hsa003301.12405950
56Autoimmune thyroid disease_Homo sapiens_hsa053201.12303526
57Cysteine and methionine metabolism_Homo sapiens_hsa002701.08829950
58Biosynthesis of amino acids_Homo sapiens_hsa012301.07955947
59Retinol metabolism_Homo sapiens_hsa008301.04478937
60Tryptophan metabolism_Homo sapiens_hsa003801.04378033
61Glycolysis / Gluconeogenesis_Homo sapiens_hsa000101.03429206
62Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.02023938
63African trypanosomiasis_Homo sapiens_hsa051431.01408894
64Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.01261471
65Pentose and glucuronate interconversions_Homo sapiens_hsa000401.00163498
66Carbon metabolism_Homo sapiens_hsa012000.95238869
67Glycerophospholipid metabolism_Homo sapiens_hsa005640.93781676
68Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.89273226
69Toll-like receptor signaling pathway_Homo sapiens_hsa046200.89234996
70PPAR signaling pathway_Homo sapiens_hsa033200.87606351
71Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.83635112
72Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.82627753
73Tuberculosis_Homo sapiens_hsa051520.82614236
74Chemical carcinogenesis_Homo sapiens_hsa052040.80742025
75Type I diabetes mellitus_Homo sapiens_hsa049400.78242017
76NOD-like receptor signaling pathway_Homo sapiens_hsa046210.77325680
77Measles_Homo sapiens_hsa051620.76877772
78Hematopoietic cell lineage_Homo sapiens_hsa046400.76776912
79Folate biosynthesis_Homo sapiens_hsa007900.76402785
80Complement and coagulation cascades_Homo sapiens_hsa046100.73200596
81Other glycan degradation_Homo sapiens_hsa005110.73196676
82Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.70731771
83Osteoclast differentiation_Homo sapiens_hsa043800.68677605
84Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.67409880
85Vitamin B6 metabolism_Homo sapiens_hsa007500.66711000
86Sulfur metabolism_Homo sapiens_hsa009200.66149557
87Peroxisome_Homo sapiens_hsa041460.65255345
88Antigen processing and presentation_Homo sapiens_hsa046120.65062863
89Jak-STAT signaling pathway_Homo sapiens_hsa046300.64629468
90Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.62354638
91Collecting duct acid secretion_Homo sapiens_hsa049660.59455729
92Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.57214725
93Lysine degradation_Homo sapiens_hsa003100.54904334
94Nitrogen metabolism_Homo sapiens_hsa009100.54727049
95Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.53879933
96Chemokine signaling pathway_Homo sapiens_hsa040620.53597626
97Phagosome_Homo sapiens_hsa041450.51288824
98Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.51283258
99Sulfur relay system_Homo sapiens_hsa041220.51266441
100Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.50495036
101Carbohydrate digestion and absorption_Homo sapiens_hsa049730.50494519
102Influenza A_Homo sapiens_hsa051640.50107601
103Glycerolipid metabolism_Homo sapiens_hsa005610.49127877
104Glycosaminoglycan degradation_Homo sapiens_hsa005310.47824896
105Pertussis_Homo sapiens_hsa051330.46629040
106Regulation of autophagy_Homo sapiens_hsa041400.45843048
107Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.45669901
108N-Glycan biosynthesis_Homo sapiens_hsa005100.44531773
109Fructose and mannose metabolism_Homo sapiens_hsa000510.43543911
110Ovarian steroidogenesis_Homo sapiens_hsa049130.41879571
111TNF signaling pathway_Homo sapiens_hsa046680.41743712
112Glutathione metabolism_Homo sapiens_hsa004800.41524196
113Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.41435145
114Protein digestion and absorption_Homo sapiens_hsa049740.41117507
115Tyrosine metabolism_Homo sapiens_hsa003500.38849470
116Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.35885118
117SNARE interactions in vesicular transport_Homo sapiens_hsa041300.32875903
118One carbon pool by folate_Homo sapiens_hsa006700.32855267
119Apoptosis_Homo sapiens_hsa042100.32299818
120Drug metabolism - other enzymes_Homo sapiens_hsa009830.31439027
121Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.30140236
122Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.30100119
123Prion diseases_Homo sapiens_hsa050200.30048717
124Fatty acid biosynthesis_Homo sapiens_hsa000610.29335775
125Olfactory transduction_Homo sapiens_hsa047400.28806728
126Metabolic pathways_Homo sapiens_hsa011000.27687368
127Bile secretion_Homo sapiens_hsa049760.27626911
128Thyroid hormone synthesis_Homo sapiens_hsa049180.27464514
129Salmonella infection_Homo sapiens_hsa051320.27287407
130Hepatitis C_Homo sapiens_hsa051600.24885516
131Taste transduction_Homo sapiens_hsa047420.24549250
132Glucagon signaling pathway_Homo sapiens_hsa049220.24478223
133Herpes simplex infection_Homo sapiens_hsa051680.24142801
134Insulin resistance_Homo sapiens_hsa049310.23476060
135Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.22555402
136Primary bile acid biosynthesis_Homo sapiens_hsa001200.22357011
137Basal transcription factors_Homo sapiens_hsa030220.12368706
138ECM-receptor interaction_Homo sapiens_hsa045120.10916652
139Pentose phosphate pathway_Homo sapiens_hsa000300.10861684
140Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.07382518
141Circadian rhythm_Homo sapiens_hsa047100.04882274
142Central carbon metabolism in cancer_Homo sapiens_hsa052300.04271753
143Other types of O-glycan biosynthesis_Homo sapiens_hsa00514-0.0753010
144Insulin signaling pathway_Homo sapiens_hsa04910-0.0495523
145TGF-beta signaling pathway_Homo sapiens_hsa04350-0.0140264
146Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550-0.0056679

Most similar genes based on co-expression Upload to Enrichr

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