UNK

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1activated T cell proliferation (GO:0050798)6.82567735
2positive regulation of glycoprotein biosynthetic process (GO:0010560)6.00117198
3transcription from RNA polymerase I promoter (GO:0006360)5.93701979
4ncRNA 3-end processing (GO:0043628)5.84512272
5regulation of protein glycosylation (GO:0060049)5.78632538
6diacylglycerol metabolic process (GO:0046339)5.63545913
7positive regulation of glycoprotein metabolic process (GO:1903020)5.33622968
8DNA unwinding involved in DNA replication (GO:0006268)5.00314267
9negative regulation of mRNA splicing, via spliceosome (GO:0048025)4.65074161
10dosage compensation (GO:0007549)4.59319406
11cellular anion homeostasis (GO:0030002)4.23527996
12embryonic process involved in female pregnancy (GO:0060136)4.20017142
13modulation by virus of host process (GO:0019054)4.16768786
14negative regulation of RNA splicing (GO:0033119)4.12441296
15protein localization to kinetochore (GO:0034501)4.10219261
16deoxyribose phosphate biosynthetic process (GO:0046385)4.07844378
172-deoxyribonucleotide biosynthetic process (GO:0009265)4.07844378
18snRNA metabolic process (GO:0016073)4.04739879
19negative regulation of histone methylation (GO:0031061)3.99954615
20neutrophil activation involved in immune response (GO:0002283)3.94374577
21negative regulation of mRNA processing (GO:0050686)3.92026345
22heterotypic cell-cell adhesion (GO:0034113)3.90655784
23DNA strand elongation involved in DNA replication (GO:0006271)3.90370656
24regulation of spindle checkpoint (GO:0090231)3.85743619
25snRNA processing (GO:0016180)3.85221107
26viral mRNA export from host cell nucleus (GO:0046784)3.79350728
27histone H2B ubiquitination (GO:0033523)3.78106750
28DNA strand elongation (GO:0022616)3.74750962
29spermatid nucleus differentiation (GO:0007289)3.73331772
30regulation of metalloenzyme activity (GO:0048552)3.72793650
31embryonic body morphogenesis (GO:0010172)3.70654020
32pyrimidine deoxyribonucleotide metabolic process (GO:0009219)3.67117997
33DNA strand renaturation (GO:0000733)3.64236332
34leukocyte cell-cell adhesion (GO:0007159)3.62418811
35telomere maintenance via semi-conservative replication (GO:0032201)3.61847198
36ubiquinone biosynthetic process (GO:0006744)3.58179969
37protein localization to microtubule (GO:0035372)3.57586328
38regulation of histone H3-K9 methylation (GO:0051570)3.54737037
39protein-DNA complex disassembly (GO:0032986)3.49322648
40nucleosome disassembly (GO:0006337)3.49322648
41translesion synthesis (GO:0019985)3.49234092
42pyrimidine nucleoside triphosphate metabolic process (GO:0009147)3.49070919
43DNA replication initiation (GO:0006270)3.48417144
44receptor clustering (GO:0043113)3.46299064
45modulation by symbiont of host cellular process (GO:0044068)3.44996063
46protein localization to chromosome, centromeric region (GO:0071459)3.40934467
47autophagic vacuole fusion (GO:0000046)3.40642105
48pre-miRNA processing (GO:0031054)3.40584530
49negative regulation of mRNA metabolic process (GO:1903312)3.40043006
50pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)3.32759255
51mitotic sister chromatid cohesion (GO:0007064)3.31727514
52formation of translation preinitiation complex (GO:0001731)3.30842722
53DNA duplex unwinding (GO:0032508)3.28203669
54DNA geometric change (GO:0032392)3.28113097
55xenobiotic catabolic process (GO:0042178)3.27393708
56maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)3.26790399
57transcription elongation from RNA polymerase I promoter (GO:0006362)3.25809327
58positive regulation of endothelial cell apoptotic process (GO:2000353)3.24754669
59mitotic nuclear envelope disassembly (GO:0007077)3.24737987
60negative regulation of tumor necrosis factor-mediated signaling pathway (GO:0010804)3.23220804
61body morphogenesis (GO:0010171)3.22121268
62sister chromatid segregation (GO:0000819)3.17172483
63regulation of chromatin binding (GO:0035561)3.13293230
64regulation of cell cycle checkpoint (GO:1901976)3.12995591
65positive regulation of transcription regulatory region DNA binding (GO:2000679)3.12891320
66telomere maintenance via recombination (GO:0000722)3.12727626
67nucleotide-excision repair, DNA gap filling (GO:0006297)3.11745800
68negative regulation of erythrocyte differentiation (GO:0045647)3.07852080
69ubiquinone metabolic process (GO:0006743)3.06936639
70mitotic recombination (GO:0006312)3.05800515
71mRNA polyadenylation (GO:0006378)3.05375627
72negative regulation of gene expression, epigenetic (GO:0045814)3.04802270
73histone H2A acetylation (GO:0043968)3.04601683
74deoxyribonucleotide biosynthetic process (GO:0009263)3.03541912
75antigen processing and presentation of endogenous peptide antigen (GO:0002483)3.02221782
76mitotic sister chromatid segregation (GO:0000070)3.02151979
77RNA polyadenylation (GO:0043631)2.99918324
78membrane disassembly (GO:0030397)2.99314116
79nuclear envelope disassembly (GO:0051081)2.99314116
80termination of RNA polymerase I transcription (GO:0006363)2.99054362
81mitotic chromosome condensation (GO:0007076)2.98614311
82ribosomal small subunit biogenesis (GO:0042274)2.95724142
83base-excision repair (GO:0006284)2.95419398
84telomere maintenance via telomere lengthening (GO:0010833)2.94277223
85establishment of mitotic spindle localization (GO:0040001)2.93358215
86spliceosomal tri-snRNP complex assembly (GO:0000244)2.93253421
87replication fork processing (GO:0031297)2.92698817
88peptidyl-lysine dimethylation (GO:0018027)2.91332557
89IMP biosynthetic process (GO:0006188)2.88816419
90DNA topological change (GO:0006265)2.88739729
91histone H4-K5 acetylation (GO:0043981)2.87673001
92histone H4-K8 acetylation (GO:0043982)2.87673001
93regulation of DNA damage checkpoint (GO:2000001)2.87605083
94termination of RNA polymerase II transcription (GO:0006369)2.86646070
95positive regulation of DNA-templated transcription, elongation (GO:0032786)2.84923103
96response to misfolded protein (GO:0051788)2.83752244
97T cell apoptotic process (GO:0070231)2.82542336
983-UTR-mediated mRNA stabilization (GO:0070935)2.82114138
99positive regulation of gene expression, epigenetic (GO:0045815)2.80750967
100mRNA splicing, via spliceosome (GO:0000398)2.79806149
101RNA splicing, via transesterification reactions with bulged adenosine as nucleophile (GO:0000377)2.79806149
102kinetochore organization (GO:0051383)2.79098483
103quinone biosynthetic process (GO:1901663)2.78540249
104regulation of glycoprotein biosynthetic process (GO:0010559)2.77656460
105antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)2.77119866
106regulation of mammary gland epithelial cell proliferation (GO:0033599)2.75913473
107RNA splicing, via transesterification reactions (GO:0000375)2.75296585
108positive regulation of cell cycle checkpoint (GO:1901978)2.75219274
109DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 cla2.74390761
110positive regulation of gamma-delta T cell activation (GO:0046645)2.74215264
111regulation of histone H3-K4 methylation (GO:0051569)2.73949697
112RNA 3-end processing (GO:0031123)2.73353008
113DNA replication checkpoint (GO:0000076)2.72832406
114synaptonemal complex assembly (GO:0007130)2.71593578
115deoxyribonucleoside monophosphate metabolic process (GO:0009162)2.71356238
116regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450912.71267931
117protein localization to chromosome (GO:0034502)2.70580829
118regulation of spindle organization (GO:0090224)2.70374571
119postreplication repair (GO:0006301)2.69287007
120DNA damage response, signal transduction resulting in transcription (GO:0042772)2.68666172
121RNA export from nucleus (GO:0006405)2.68464116
122DNA conformation change (GO:0071103)2.68266026
123transcription initiation from RNA polymerase I promoter (GO:0006361)2.67890950
124negative regulation of DNA-templated transcription, elongation (GO:0032785)2.67767268
125negative regulation of transcription elongation from RNA polymerase II promoter (GO:0034244)2.67767268
126mRNA export from nucleus (GO:0006406)2.67210834
127intracellular estrogen receptor signaling pathway (GO:0030520)2.67080820
128DNA deamination (GO:0045006)2.66588391
129regulation of translational fidelity (GO:0006450)2.65905866
130mitotic metaphase plate congression (GO:0007080)2.65698258
131folic acid-containing compound biosynthetic process (GO:0009396)2.65521431
132histone H4-K16 acetylation (GO:0043984)2.64695382
133histone H4-K12 acetylation (GO:0043983)2.64534038
134mRNA 3-end processing (GO:0031124)2.63718254
135RNA stabilization (GO:0043489)2.63461903
136mRNA stabilization (GO:0048255)2.63461903
137receptor internalization (GO:0031623)2.63334428
138metaphase plate congression (GO:0051310)2.63167393
139negative regulation of proteasomal ubiquitin-dependent protein catabolic process (GO:0032435)2.62167321
140mismatch repair (GO:0006298)2.61061873
141kinetochore assembly (GO:0051382)2.60675122
142necroptotic process (GO:0070266)2.60451629
143regulation of attachment of spindle microtubules to kinetochore (GO:0051988)2.60409650
144chromatin assembly or disassembly (GO:0006333)2.60149680
145nuclear envelope organization (GO:0006998)2.59201312
146negative regulation of execution phase of apoptosis (GO:1900118)2.58839607
147protein polyglutamylation (GO:0018095)2.58759289
148alternative mRNA splicing, via spliceosome (GO:0000380)2.58211531
149heterochromatin organization (GO:0070828)2.58178581
150modulation by virus of host morphology or physiology (GO:0019048)2.57891728
151antigen processing and presentation of endogenous antigen (GO:0019883)2.57802381
152glucocorticoid receptor signaling pathway (GO:0042921)2.56970641
153nuclear pore organization (GO:0006999)2.56492550
154ribosomal small subunit assembly (GO:0000028)2.56430386
155negative regulation of histone modification (GO:0031057)2.55766164
156regulation of sister chromatid cohesion (GO:0007063)2.55419733
157regulation of NFAT protein import into nucleus (GO:0051532)2.55407057
158histone H3-K4 trimethylation (GO:0080182)2.54969814
159histone H3-K4 methylation (GO:0051568)2.54525121
160embryonic skeletal joint morphogenesis (GO:0060272)2.54258311
161nuclear pore complex assembly (GO:0051292)2.54059927
162DNA replication-independent nucleosome assembly (GO:0006336)2.53822925
163DNA replication-independent nucleosome organization (GO:0034724)2.53822925
164regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)2.53538853
165meiotic chromosome segregation (GO:0045132)2.53531294
166positive regulation by host of viral transcription (GO:0043923)2.53045528
167histone H4 acetylation (GO:0043967)2.52731890
168mRNA splice site selection (GO:0006376)2.52442213
169DNA demethylation (GO:0080111)2.52400256
170peptidyl-arginine omega-N-methylation (GO:0035247)2.51724060
171UTP metabolic process (GO:0046051)2.51184839
172regulation of cilium assembly (GO:1902017)2.51102581
173cellular response to virus (GO:0098586)2.50979083
174mitochondrion distribution (GO:0048311)2.50470697
175peptidyl-lysine trimethylation (GO:0018023)2.49785161
176regulation of defense response to virus by virus (GO:0050690)2.49601482
177mRNA transport (GO:0051028)2.48337055
178positive regulation of mitotic sister chromatid separation (GO:1901970)2.48117661
179positive regulation of mitotic metaphase/anaphase transition (GO:0045842)2.48117661
180positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)2.48117661

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human9.15669926
2FOXM1_23109430_ChIP-Seq_U2OS_Human4.67628946
3MYC_22102868_ChIP-Seq_BL_Human3.79971650
4EGR1_19374776_ChIP-ChIP_THP-1_Human3.67265796
5E2F4_17652178_ChIP-ChIP_JURKAT_Human3.19985467
6VDR_21846776_ChIP-Seq_THP-1_Human2.90800847
7* MYC_18555785_ChIP-Seq_MESCs_Mouse2.83986240
8EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.82039502
9FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.76933257
10CIITA_25753668_ChIP-Seq_RAJI_Human2.62433211
11MYC_19079543_ChIP-ChIP_MESCs_Mouse2.11028095
12CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.07297640
13NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.02028160
14TCF7_22412390_ChIP-Seq_EML_Mouse1.97904640
15E2F1_21310950_ChIP-Seq_MCF-7_Human1.96392625
16SCL_19346495_ChIP-Seq_HPC-7_Human1.95637715
17SRY_22984422_ChIP-ChIP_TESTIS_Rat1.95525159
18TP63_19390658_ChIP-ChIP_HaCaT_Human1.93828054
19* MYC_19030024_ChIP-ChIP_MESCs_Mouse1.84737526
20RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.84190041
21XRN2_22483619_ChIP-Seq_HELA_Human1.83645967
22E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.80953988
23CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.80715820
24CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.77276960
25ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.76387548
26MYC_18358816_ChIP-ChIP_MESCs_Mouse1.72298968
27TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.71293392
28TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.70762057
29SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.70721813
30P68_20966046_ChIP-Seq_HELA_Human1.70168010
31YY1_21170310_ChIP-Seq_MESCs_Mouse1.66979818
32SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.63594917
33KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.63050666
34ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.62610313
35KDM2B_26808549_Chip-Seq_DND41_Human1.62021225
36RACK7_27058665_Chip-Seq_MCF-7_Human1.58509258
37KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.57490821
38STAT3_1855785_ChIP-Seq_MESCs_Mouse1.57173303
39KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.56855927
40* HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.56239255
41VDR_24763502_ChIP-Seq_THP-1_Human1.52092836
42ELF1_20517297_ChIP-Seq_JURKAT_Human1.51914851
43NELFA_20434984_ChIP-Seq_ESCs_Mouse1.51333321
44KDM2B_26808549_Chip-Seq_SUP-B15_Human1.50422751
45* MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.49762159
46* BCL6_27268052_Chip-Seq_Bcells_Human1.49749280
47DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.49447118
48* CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.48647568
49* UTX_26944678_Chip-Seq_JUKART_Human1.48177733
50BCOR_27268052_Chip-Seq_Bcells_Human1.47970234
51MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.46954757
52HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse1.45257790
53BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.44703286
54YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.41354903
55KDM5A_27292631_Chip-Seq_BREAST_Human1.41130795
56AR_21909140_ChIP-Seq_LNCAP_Human1.40628807
57CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.40310299
58CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.40259382
59MAF_26560356_Chip-Seq_TH1_Human1.40176819
60* SREBP1_19666523_ChIP-Seq_LIVER_Mouse1.37563638
61NANOG_18555785_ChIP-Seq_MESCs_Mouse1.37054562
62TP53_22127205_ChIP-Seq_IMR90_Human1.36627662
63DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.36600511
64MYCN_18555785_ChIP-Seq_MESCs_Mouse1.35706224
65SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.35422246
66ELK3_25401928_ChIP-Seq_HUVEC_Human1.35097390
67SOX2_18555785_ChIP-Seq_MESCs_Mouse1.34004614
68GATA1_22025678_ChIP-Seq_K562_Human1.33955571
69PHF8_20622854_ChIP-Seq_HELA_Human1.33712181
70* SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.33007268
71ERG_21242973_ChIP-ChIP_JURKAT_Human1.32409889
72TET1_21451524_ChIP-Seq_MESCs_Mouse1.30265471
73* CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.29664555
74SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.28929813
75POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.27104434
76PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.27035156
77SMC4_20622854_ChIP-Seq_HELA_Human1.26794636
78TTF2_22483619_ChIP-Seq_HELA_Human1.25844791
79* THAP11_20581084_ChIP-Seq_MESCs_Mouse1.25670449
80* ZFX_18555785_ChIP-Seq_MESCs_Mouse1.24658510
81GABP_19822575_ChIP-Seq_HepG2_Human1.22736833
82BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.22730094
83FOXP3_21729870_ChIP-Seq_TREG_Human1.21475505
84ELF1_17652178_ChIP-ChIP_JURKAT_Human1.20427190
85E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.19517231
86NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.19290236
87NANOG_21062744_ChIP-ChIP_HESCs_Human1.19237231
88* BRD4_27068464_Chip-Seq_AML-cells_Mouse1.18707433
89ZFP281_18757296_ChIP-ChIP_E14_Mouse1.18227661
90STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.17828516
91CTCF_26484167_Chip-Seq_Bcells_Mouse1.17742566
92* SA1_27219007_Chip-Seq_ERYTHROID_Human1.17672080
93MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.17502508
94* ZFP281_27345836_Chip-Seq_ESCs_Mouse1.16895120
95BP1_19119308_ChIP-ChIP_Hs578T_Human1.16011221
96FOXP1_21924763_ChIP-Seq_HESCs_Human1.15730687
97MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.14052420
98DCP1A_22483619_ChIP-Seq_HELA_Human1.13667589
99GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.12199588
100MYB_26560356_Chip-Seq_TH1_Human1.12116974
101VDR_23849224_ChIP-Seq_CD4+_Human1.11954938
102PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.11414160
103CTCF_27219007_Chip-Seq_ERYTHROID_Human1.11384949
104RARB_24833708_ChIP-Seq_LIVER_Mouse1.11199097
105SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.11116442
106* PU.1_20513432_ChIP-Seq_Bcells_Mouse1.10914471
107* SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.10377966
108KDM2B_26808549_Chip-Seq_JURKAT_Human1.10344523
109DNAJC2_21179169_ChIP-ChIP_NT2_Human1.10263570
110DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.09824124
111* ETS1_20019798_ChIP-Seq_JURKAT_Human1.08858277
112MAF_26560356_Chip-Seq_TH2_Human1.07693677
113* E2F1_18555785_ChIP-Seq_MESCs_Mouse1.06944134
114* FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.06806111
115TFEB_21752829_ChIP-Seq_HELA_Human1.06596328
116LXR_22292898_ChIP-Seq_THP-1_Human1.05755606
117* TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.04855099
118* MYB_26560356_Chip-Seq_TH2_Human1.04651401
119KLF4_18555785_ChIP-Seq_MESCs_Mouse1.04317530
120NOTCH1_21737748_ChIP-Seq_TLL_Human1.04180041
121EST1_17652178_ChIP-ChIP_JURKAT_Human1.04076612
122STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.03885732
123ERG_20887958_ChIP-Seq_HPC-7_Mouse1.03858187
124E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.03113962
125KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.02499279
126EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.01764234
127RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.01198449
128* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.99862297
129* RUNX1_22412390_ChIP-Seq_EML_Mouse0.99789596
130* SPI1_23547873_ChIP-Seq_NB4_Human0.99294114
131NCOR1_26117541_ChIP-Seq_K562_Human0.98535944
132GATA1_22383799_ChIP-Seq_G1ME_Mouse0.97961634
133ZIC3_20872845_ChIP-ChIP_MESCs_Mouse0.96774470
134KLF4_18358816_ChIP-ChIP_MESCs_Mouse0.96695757
135PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse0.96320117
136CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.95100990
137JARID1A_20064375_ChIP-Seq_MESCs_Mouse0.94797118
138SMAD3_22036565_ChIP-Seq_ESCs_Mouse0.94781077
139RBPJ_22232070_ChIP-Seq_NCS_Mouse0.94205264
140HOXB4_20404135_ChIP-ChIP_EML_Mouse0.92377822
141HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse0.90234750

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008260_abnormal_autophagy4.79528874
2MP0010094_abnormal_chromosome_stability3.59904058
3MP0002396_abnormal_hematopoietic_system3.26617541
4MP0003111_abnormal_nucleus_morphology3.26365216
5MP0003693_abnormal_embryo_hatching3.11829343
6MP0003172_abnormal_lysosome_physiology2.96516282
7MP0002933_joint_inflammation2.93833131
8MP0003077_abnormal_cell_cycle2.91569867
9MP0008057_abnormal_DNA_replication2.91086283
10MP0009278_abnormal_bone_marrow2.56796665
11MP0008007_abnormal_cellular_replicative2.37525927
12MP0004381_abnormal_hair_follicle2.30648075
13MP0001835_abnormal_antigen_presentation2.26402784
14MP0001851_eye_inflammation2.25527247
15MP0004808_abnormal_hematopoietic_stem2.22680632
16MP0005670_abnormal_white_adipose2.22532791
17MP0006035_abnormal_mitochondrial_morpho2.18619544
18MP0005076_abnormal_cell_differentiation2.10284696
19MP0008058_abnormal_DNA_repair2.10200548
20MP0004957_abnormal_blastocyst_morpholog2.06725944
21MP0003646_muscle_fatigue2.00627016
22MP0004947_skin_inflammation1.95810772
23MP0010030_abnormal_orbit_morphology1.87395173
24MP0003121_genomic_imprinting1.86001416
25MP0000350_abnormal_cell_proliferation1.85608500
26MP0005671_abnormal_response_to1.84471330
27MP0001545_abnormal_hematopoietic_system1.81786769
28MP0005397_hematopoietic_system_phenotyp1.81786769
29MP0005000_abnormal_immune_tolerance1.75846123
30MP0001529_abnormal_vocalization1.74243022
31MP0005058_abnormal_lysosome_morphology1.73268246
32MP0000537_abnormal_urethra_morphology1.71200057
33MP0000490_abnormal_crypts_of1.69990321
34MP0003283_abnormal_digestive_organ1.69672922
35MP0001853_heart_inflammation1.65799589
36MP0001293_anophthalmia1.64670112
37MP0002653_abnormal_ependyma_morphology1.64305429
38MP0005075_abnormal_melanosome_morpholog1.62198342
39MP0003763_abnormal_thymus_physiology1.61863509
40MP0000703_abnormal_thymus_morphology1.61167971
41MP0001730_embryonic_growth_arrest1.61060155
42MP0004197_abnormal_fetal_growth/weight/1.59989021
43MP0005025_abnormal_response_to1.58195518
44MP0003878_abnormal_ear_physiology1.56048708
45MP0005377_hearing/vestibular/ear_phenot1.56048708
46MP0003123_paternal_imprinting1.56037925
47MP0002085_abnormal_embryonic_tissue1.52713642
48MP0010307_abnormal_tumor_latency1.52682641
49MP0003122_maternal_imprinting1.51939949
50MP0002723_abnormal_immune_serum1.51701970
51MP0001727_abnormal_embryo_implantation1.51601737
52MP0008961_abnormal_basal_metabolism1.50214844
53MP0005408_hypopigmentation1.47377482
54MP0002084_abnormal_developmental_patter1.46775802
55MP0006082_CNS_inflammation1.43953321
56MP0010352_gastrointestinal_tract_polyps1.43718926
57MP0001672_abnormal_embryogenesis/_devel1.43467788
58MP0005380_embryogenesis_phenotype1.43467788
59MP0002398_abnormal_bone_marrow1.43226962
60MP0000858_altered_metastatic_potential1.39128601
61MP0001697_abnormal_embryo_size1.36372754
62MP0002088_abnormal_embryonic_growth/wei1.36003027
63MP0003984_embryonic_growth_retardation1.35978347
64MP0002419_abnormal_innate_immunity1.34524663
65MP0003119_abnormal_digestive_system1.34199786
66MP0002089_abnormal_postnatal_growth/wei1.33712264
67MP0002452_abnormal_antigen_presenting1.32389476
68MP0008932_abnormal_embryonic_tissue1.30898996
69MP0003786_premature_aging1.30428777
70MP0002080_prenatal_lethality1.30111228
71MP0002086_abnormal_extraembryonic_tissu1.29980877
72MP0000358_abnormal_cell_content/1.28606541
73MP0002234_abnormal_pharynx_morphology1.28358589
74MP0002932_abnormal_joint_morphology1.28101886
75MP0000465_gastrointestinal_hemorrhage1.27343916
76MP0003866_abnormal_defecation1.24178789
77MP0003436_decreased_susceptibility_to1.23712122
78MP0003724_increased_susceptibility_to1.22548134
79MP0000313_abnormal_cell_death1.19888391
80MP0001191_abnormal_skin_condition1.18973120
81MP0002722_abnormal_immune_system1.17830636
82MP0003300_gastrointestinal_ulcer1.17585097
83MP0002019_abnormal_tumor_incidence1.17165734
84MP0008877_abnormal_DNA_methylation1.15886236
85MP0006054_spinal_hemorrhage1.15352510
86MP0008995_early_reproductive_senescence1.13576719
87MP0000681_abnormal_thyroid_gland1.13439182
88MP0000569_abnormal_digit_pigmentation1.12536280
89MP0001819_abnormal_immune_cell1.12154157
90MP0003890_abnormal_embryonic-extraembry1.11273863
91MP0000689_abnormal_spleen_morphology1.10929272
92MP0009053_abnormal_anal_canal1.10735055
93MP0003115_abnormal_respiratory_system1.10201921
94MP0001849_ear_inflammation1.10019086
95MP0003567_abnormal_fetal_cardiomyocyte1.09756068
96MP0003705_abnormal_hypodermis_morpholog1.09590499
97MP0002092_abnormal_eye_morphology1.09453031
98MP0000049_abnormal_middle_ear1.09314809
99MP0000428_abnormal_craniofacial_morphol1.09220894
100MP0000678_abnormal_parathyroid_gland1.06926957
101MP0006292_abnormal_olfactory_placode1.06536466
102MP0003942_abnormal_urinary_system1.03340105
103MP0003935_abnormal_craniofacial_develop1.02701303
104MP0000371_diluted_coat_color1.01038852
105MP0002282_abnormal_trachea_morphology1.00881476
106MP0003787_abnormal_imprinting1.00574842
107MP0002429_abnormal_blood_cell0.99535793
108MP0000685_abnormal_immune_system0.98222457
109MP0002925_abnormal_cardiovascular_devel0.97462281
110MP0002697_abnormal_eye_size0.96848623
111MP0004858_abnormal_nervous_system0.96616186
112MP0000377_abnormal_hair_follicle0.96424567
113MP0009333_abnormal_splenocyte_physiolog0.96216439
114MP0004133_heterotaxia0.94783431
115MP0002877_abnormal_melanocyte_morpholog0.94255698
116MP0000716_abnormal_immune_system0.93459605
117MP0003329_amyloid_beta_deposits0.92664478
118MP0004142_abnormal_muscle_tone0.92545038
119MP0005464_abnormal_platelet_physiology0.91995494
120MP0003943_abnormal_hepatobiliary_system0.90321319
121MP0005448_abnormal_energy_balance0.90232118
122MP0000367_abnormal_coat/_hair0.90163857
123MP0004924_abnormal_behavior0.89114834
124MP0005386_behavior/neurological_phenoty0.89114834
125MP0000733_abnormal_muscle_development0.87852486
126MP0009115_abnormal_fat_cell0.87272759
127MP0010155_abnormal_intestine_physiology0.86815296
128MP0001915_intracranial_hemorrhage0.86537543
129MP0003566_abnormal_cell_adhesion0.86454231
130MP0001800_abnormal_humoral_immune0.84636845
131MP0002938_white_spotting0.84125640
132MP0004185_abnormal_adipocyte_glucose0.83917912
133MP0002116_abnormal_craniofacial_bone0.83812402
134MP0005666_abnormal_adipose_tissue0.83594012
135MP0002249_abnormal_larynx_morphology0.83406847
136MP0002111_abnormal_tail_morphology0.83360849
137MP0002277_abnormal_respiratory_mucosa0.83295081
138MP0009931_abnormal_skin_appearance0.82797186
139MP0009672_abnormal_birth_weight0.81397583
140MP0005253_abnormal_eye_physiology0.80732237
141MP0005387_immune_system_phenotype0.80669884
142MP0001790_abnormal_immune_system0.80669884
143MP0000372_irregular_coat_pigmentation0.79991935
144MP0000015_abnormal_ear_pigmentation0.78972744
145MP0008469_abnormal_protein_level0.78446589
146MP0000003_abnormal_adipose_tissue0.78269038
147MP0001286_abnormal_eye_development0.76266661
148MP0005197_abnormal_uvea_morphology0.75725576
149MP0004233_abnormal_muscle_weight0.75601742
150MP0003861_abnormal_nervous_system0.75117048
151MP0002210_abnormal_sex_determination0.74525839
152MP0006036_abnormal_mitochondrial_physio0.74453848
153MP0000266_abnormal_heart_morphology0.74437185
154MP0005621_abnormal_cell_physiology0.73733142
155MP0002075_abnormal_coat/hair_pigmentati0.72058728
156MP0000432_abnormal_head_morphology0.71153998
157MP0002114_abnormal_axial_skeleton0.70926937
158MP0002420_abnormal_adaptive_immunity0.70794509
159MP0000477_abnormal_intestine_morphology0.69468720
160MP0000534_abnormal_ureter_morphology0.69142741

Predicted human phenotypes

RankGene SetZ-score
1Recurrent gram-negative bacterial infections (HP:0005420)8.63135829
2Gingivitis (HP:0000230)6.72133125
3Periodontitis (HP:0000704)5.98815945
4Recurrent abscess formation (HP:0002722)5.64250248
5Increased IgM level (HP:0003496)5.54602105
6Sparse scalp hair (HP:0002209)5.32851583
7Nasal speech (HP:0001611)4.75791381
8Leukocytosis (HP:0001974)4.51141795
9Deep philtrum (HP:0002002)4.38904049
10Aplasia/Hypoplasia of the sacrum (HP:0008517)4.20049058
11Abnormality of the fingertips (HP:0001211)3.97139233
12Respiratory insufficiency due to defective ciliary clearance (HP:0200073)3.68379819
13Broad distal phalanx of finger (HP:0009836)3.62293252
14Hyperacusis (HP:0010780)3.45043081
15Metaphyseal cupping (HP:0003021)3.42167178
16Chronic bronchitis (HP:0004469)3.34544200
17Short 4th metacarpal (HP:0010044)3.22424536
18Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)3.22424536
19Autoimmune thrombocytopenia (HP:0001973)3.20822810
20Abnormality of T cell physiology (HP:0011840)3.14583422
21Autoimmune hemolytic anemia (HP:0001890)3.10136187
22Granulocytopenia (HP:0001913)3.09847531
23Ependymoma (HP:0002888)3.06657474
24Cupped ribs (HP:0000887)3.04171728
25Abnormality of the aortic arch (HP:0012303)2.94492732
26Eosinophilia (HP:0001880)2.90823554
27Achilles tendon contracture (HP:0001771)2.90134828
28Microvesicular hepatic steatosis (HP:0001414)2.89854633
29Renal duplication (HP:0000075)2.87484884
30Stomatitis (HP:0010280)2.83556256
31Increased IgE level (HP:0003212)2.73165230
32Abnormal number of incisors (HP:0011064)2.66133832
33Abnormality of the Achilles tendon (HP:0005109)2.59354696
34Selective tooth agenesis (HP:0001592)2.48647906
35Increased nuchal translucency (HP:0010880)2.46268784
36Medulloblastoma (HP:0002885)2.45528898
37Abnormal large intestine physiology (HP:0012700)2.42438927
38Bowel incontinence (HP:0002607)2.42057823
39Partial agenesis of the corpus callosum (HP:0001338)2.38819077
40Abnormality of eosinophils (HP:0001879)2.38357737
41High pitched voice (HP:0001620)2.38053238
42Long eyelashes (HP:0000527)2.37960050
43Elfin facies (HP:0004428)2.37324787
44Cellulitis (HP:0100658)2.36747743
45Absent hand (HP:0004050)2.35796207
46Colon cancer (HP:0003003)2.34532431
47Hypochromic anemia (HP:0001931)2.32293860
48Broad palm (HP:0001169)2.27635829
49Eczematoid dermatitis (HP:0000976)2.25841715
50Hypoplastic toenails (HP:0001800)2.25635335
51Hypoplasia of the capital femoral epiphysis (HP:0003090)2.25096200
52Renovascular hypertension (HP:0100817)2.24644174
53Patellar aplasia (HP:0006443)2.24504004
54Ectopic kidney (HP:0000086)2.23363588
55Recurrent otitis media (HP:0000403)2.23118885
56Abnormality of T cells (HP:0002843)2.21555418
57Myelodysplasia (HP:0002863)2.20066107
58Birth length less than 3rd percentile (HP:0003561)2.18433754
59Overriding aorta (HP:0002623)2.18250436
60Abnormality of the tricuspid valve (HP:0001702)2.17562665
61Truncus arteriosus (HP:0001660)2.15415351
62Abnormality of the 4th metacarpal (HP:0010012)2.13638650
63Chromsome breakage (HP:0040012)2.13317900
64Increased neuronal autofluorescent lipopigment (HP:0002074)2.11705478
65Neoplasm of the oral cavity (HP:0100649)2.11541538
66Abnormality of lateral ventricle (HP:0030047)2.09618777
67Cortical visual impairment (HP:0100704)2.08997841
68Atelectasis (HP:0100750)2.07890265
69Reticulocytopenia (HP:0001896)2.07560388
70Abnormality of the astrocytes (HP:0100707)2.07524157
71Astrocytoma (HP:0009592)2.07524157
72Agammaglobulinemia (HP:0004432)2.03860885
73Cerebral aneurysm (HP:0004944)2.03743907
74Aplasia/Hypoplasia of the patella (HP:0006498)2.02875144
75Chromosomal breakage induced by crosslinking agents (HP:0003221)2.02781050
76Insomnia (HP:0100785)2.02156094
77Acute lymphatic leukemia (HP:0006721)2.01703977
78Hypergammaglobulinemia (HP:0010702)2.01328910
79Broad phalanges of the hand (HP:0009768)1.99196568
80Trigonocephaly (HP:0000243)1.99116262
81Flat cornea (HP:0007720)1.97624195
82Colitis (HP:0002583)1.97125148
83Broad thumb (HP:0011304)1.96325078
84Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)1.96214027
85Absent epiphyses (HP:0010577)1.96214027
8611 pairs of ribs (HP:0000878)1.95620230
87Abnormality of the carotid arteries (HP:0005344)1.95264232
88Abnormality of the columella (HP:0009929)1.95015416
89Prominent nose (HP:0000448)1.94873994
90Short 5th finger (HP:0009237)1.93380116
91Skin tags (HP:0010609)1.92196305
92Persistence of primary teeth (HP:0006335)1.91770463
93Progressive muscle weakness (HP:0003323)1.91554260
94Basal cell carcinoma (HP:0002671)1.91446521
95Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)1.89889997
96Systemic lupus erythematosus (HP:0002725)1.89531486
97Seborrheic dermatitis (HP:0001051)1.89457494
98Slender long bone (HP:0003100)1.89382631
99Cerebellar dysplasia (HP:0007033)1.88255980
100Shallow orbits (HP:0000586)1.88093519
101Hypopigmentation of the fundus (HP:0007894)1.87437414
102Anal stenosis (HP:0002025)1.87434304
103Broad face (HP:0000283)1.84758588
104Bowel diverticulosis (HP:0005222)1.83813411
105Megalocornea (HP:0000485)1.81830069
106Increased cerebral lipofuscin (HP:0011813)1.81663242
107Aplasia/Hypoplasia of the uvula (HP:0010293)1.81303897
108Decreased electroretinogram (ERG) amplitude (HP:0000654)1.80815952
109Purpura (HP:0000979)1.80280012
110Aplasia/Hypoplasia of the 5th finger (HP:0006262)1.79130393
111Ulnar bowing (HP:0003031)1.78162241
112Neoplasm of striated muscle (HP:0009728)1.77155592
113Genetic anticipation (HP:0003743)1.76822896
114IgM deficiency (HP:0002850)1.76262315
115Cafe-au-lait spot (HP:0000957)1.76248202
116Bicuspid aortic valve (HP:0001647)1.76014347
117Broad finger (HP:0001500)1.75240751
118Aplasia/Hypoplasia of the macula (HP:0008059)1.73584889
119Abnormality of the ileum (HP:0001549)1.73059255
120Pointed chin (HP:0000307)1.72922636
121Severe visual impairment (HP:0001141)1.72644940
122Squamous cell carcinoma (HP:0002860)1.72350740
123Rib fusion (HP:0000902)1.71742072
124Small intestinal stenosis (HP:0012848)1.71177133
125Duodenal stenosis (HP:0100867)1.71177133
126Ankle contracture (HP:0006466)1.71074497
127Broad phalanx (HP:0006009)1.70033243
128Cutaneous melanoma (HP:0012056)1.69178336
129Aplasia/Hypoplasia of the sternum (HP:0006714)1.69142307
130Obstructive sleep apnea (HP:0002870)1.69033296
131Preauricular skin tag (HP:0000384)1.68988372
132Increased density of long bones (HP:0006392)1.67352097
133Prominent forehead (HP:0011220)1.67305480
134Interstitial pulmonary disease (HP:0006530)1.67090802
135Meckel diverticulum (HP:0002245)1.66619708
136Abnormality of the radial head (HP:0003995)1.65359638
137Abnormality of macular pigmentation (HP:0008002)1.64838829
138Recurrent viral infections (HP:0004429)1.63841665
139Panhypogammaglobulinemia (HP:0003139)1.62993888
140Recurrent cutaneous fungal infections (HP:0011370)1.62574537
141Chronic mucocutaneous candidiasis (HP:0002728)1.62574537
142Neoplasm of the heart (HP:0100544)1.62406457
143Lower limb asymmetry (HP:0100559)1.62174488
144Hemorrhage of the eye (HP:0011885)1.62081514
145IgG deficiency (HP:0004315)1.61879590
146Spina bifida occulta (HP:0003298)1.61608811
147Macroorchidism (HP:0000053)1.60655596
148Elevated erythrocyte sedimentation rate (HP:0003565)1.60457528
149Amaurosis fugax (HP:0100576)1.59773474
150Abnormality of chromosome segregation (HP:0002916)1.58989162
151Narrow palate (HP:0000189)1.58846763
152Missing ribs (HP:0000921)1.58192869
153Glioma (HP:0009733)1.57643761
154Abnormality of the thoracic spine (HP:0100711)1.57574124
155Abnormality of chromosome stability (HP:0003220)1.57287252
156Maternal diabetes (HP:0009800)1.57014253
157Hypoplasia of the fovea (HP:0007750)1.56218264
158Aplasia/Hypoplasia of the fovea (HP:0008060)1.56218264
159J-shaped sella turcica (HP:0002680)1.55402775
160Broad long bones (HP:0005622)1.55196271
161Webbed neck (HP:0000465)1.55002358
162Overlapping toe (HP:0001845)1.54991732
163Recurrent fungal infections (HP:0002841)1.54900506
164Dislocated radial head (HP:0003083)1.54833931
165Encephalitis (HP:0002383)1.54033429
166Thoracic kyphosis (HP:0002942)1.54032779
167Facial cleft (HP:0002006)1.53559973
168Myelomeningocele (HP:0002475)1.53461069
169Abnormality of the intervertebral disk (HP:0005108)1.52750413
170Abnormal delayed hypersensitivity skin test (HP:0002963)1.52716488
171Low posterior hairline (HP:0002162)1.52215424
172Bronchitis (HP:0012387)1.52199817
173Vasculitis (HP:0002633)1.52184642
174Tented upper lip vermilion (HP:0010804)1.52084417
175Abnormal number of erythroid precursors (HP:0012131)1.51687635
176Radial bowing (HP:0002986)1.51643794
177Bladder diverticulum (HP:0000015)1.51526050
178Hypertensive crisis (HP:0100735)1.51096131
179Proximal placement of thumb (HP:0009623)1.50758071
180Disproportionate tall stature (HP:0001519)1.50654195
181Deviation of the thumb (HP:0009603)1.50546052
182Abnormality of the duodenum (HP:0002246)1.50533685
183Spinal cord lesions (HP:0100561)1.50200703
184Syringomyelia (HP:0003396)1.50200703
185Abnormality of abdominal situs (HP:0011620)1.49964473
186Abdominal situs inversus (HP:0003363)1.49964473

Predicted kinase interactions (KEA)

RankGene SetZ-score
1EEF2K3.98208115
2PBK3.94733058
3PRKCH3.93673554
4MAP3K103.61897671
5CDK123.13495948
6TXK3.07763229
7CDC73.07527281
8FES2.76776580
9NEK22.67297875
10MAP4K12.63202226
11PKN22.59828826
12EPHB12.54596361
13BRD42.41377998
14ICK2.15734485
15TRIB32.10161351
16DYRK32.10087257
17PASK1.99946560
18NME21.93001694
19CDK71.79398327
20TGFBR11.78769035
21RPS6KB21.76802429
22ATR1.74842266
23SIK31.66470778
24PRPF4B1.65513367
25ERN11.65289288
26FGFR31.60989085
27IRAK11.59690637
28DAPK11.51697860
29FLT31.48922718
30SIK21.45879838
31CDK41.34848288
32STK101.34350008
33BUB11.31139856
34SMG11.30021154
35CSK1.25105213
36BTK1.24721719
37IRAK41.22104712
38TSSK61.22040422
39RPS6KA41.19602407
40CAMK1D1.19145400
41MTOR1.17111192
42TTK1.16720106
43WEE11.15514809
44PAK41.14384565
45SIK11.12012857
46MAPK151.10308983
47RET1.08379496
48TNK21.07863611
49HIPK21.07633372
50STK41.07229401
51EPHB21.05379131
52CHEK21.04270986
53DYRK1B1.04234280
54VRK10.97034862
55PDGFRA0.95166717
56CHEK10.92573422
57CCNB10.92418884
58CAMK1G0.92074091
59AURKB0.91545892
60PLK10.90933641
61PAK20.90778444
62UHMK10.90533398
63CDK60.89893762
64KSR10.89023072
65MAP3K80.85485132
66LCK0.84106092
67JAK30.83442698
68MAP3K110.82587217
69EPHA30.82444099
70ZAP700.82322567
71PIM10.81457669
72IRAK20.81429514
73CSF1R0.81348721
74MAP3K10.81057351
75CDK20.80559106
76PRKD30.75958740
77MAPK110.75920649
78MAPK40.74532758
79PTK60.74236916
80MATK0.73826308
81CHUK0.71026532
82LRRK20.70176239
83ATM0.69982829
84RPS6KA50.69875660
85NME10.69632090
86MKNK10.67416848
87BMX0.65961314
88ALK0.64989169
89ACVR1B0.63954303
90ERBB20.63885559
91CDK80.63656670
92BCKDK0.62913467
93NLK0.62849045
94DYRK20.62600208
95CDK90.61972418
96PIM20.61580530
97KDR0.60620116
98SCYL20.59796598
99MAP3K60.58798159
100RPS6KA60.56761308
101RPS6KC10.56561196
102RPS6KL10.56561196
103MARK20.56145512
104TGFBR20.55630557
105AKT20.53877557
106IKBKB0.53566851
107TAOK30.53513247
108CDK10.53346293
109KIT0.52679635
110SRPK10.52190313
111CDC42BPA0.51800103
112AKT10.51034041
113TYRO30.49885930
114MAPKAPK30.49429499
115CLK10.49149811
116JAK20.48603037
117TTN0.47647972
118MAP2K60.47275772
119AURKA0.46774074
120PRKD20.46228207
121MAP2K30.46226265
122TAOK10.45614581
123TYK20.44774482
124RPS6KA20.43613783
125KSR20.43404677
126CAMK40.42985960
127MAPK30.42909188
128FGFR40.42606956
129IKBKE0.42149951
130ITK0.42049609
131HCK0.41630277
132MAPK10.41568344
133MAPKAPK20.41373519
134MAPK90.40595608
135TAOK20.39676680
136GRK60.39038401
137MAPK140.39016555
138RPS6KA10.38855863
139RAF10.37888416
140FER0.36575734
141MAP3K30.33216359
142PDK10.32641325
143SRC0.30775529
144MAP3K70.30746060
145MAPK80.30287305
146PDPK10.29925960

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030304.06897515
2Mismatch repair_Homo sapiens_hsa034303.24445843
3Base excision repair_Homo sapiens_hsa034103.04608730
4Spliceosome_Homo sapiens_hsa030402.75591676
5Autoimmune thyroid disease_Homo sapiens_hsa053202.63434757
6Allograft rejection_Homo sapiens_hsa053302.49514011
7Cell cycle_Homo sapiens_hsa041102.44861572
8Staphylococcus aureus infection_Homo sapiens_hsa051502.33380632
9Cyanoamino acid metabolism_Homo sapiens_hsa004602.20535074
10Graft-versus-host disease_Homo sapiens_hsa053322.19763397
11Homologous recombination_Homo sapiens_hsa034402.02834345
12RNA transport_Homo sapiens_hsa030132.00599955
13mRNA surveillance pathway_Homo sapiens_hsa030151.99155462
14Malaria_Homo sapiens_hsa051441.93618829
15Type I diabetes mellitus_Homo sapiens_hsa049401.92022974
16Fanconi anemia pathway_Homo sapiens_hsa034601.83478292
17Notch signaling pathway_Homo sapiens_hsa043301.75522863
18Nucleotide excision repair_Homo sapiens_hsa034201.66842508
19Chronic myeloid leukemia_Homo sapiens_hsa052201.66154215
20One carbon pool by folate_Homo sapiens_hsa006701.63715695
21Non-homologous end-joining_Homo sapiens_hsa034501.58292265
22Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.54926340
23Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.49216769
24Pertussis_Homo sapiens_hsa051331.45261998
25Transcriptional misregulation in cancer_Homo sapiens_hsa052021.42574043
26RNA degradation_Homo sapiens_hsa030181.39713207
27Basal cell carcinoma_Homo sapiens_hsa052171.39675969
28Glycerophospholipid metabolism_Homo sapiens_hsa005641.37931923
29Colorectal cancer_Homo sapiens_hsa052101.35994655
30MicroRNAs in cancer_Homo sapiens_hsa052061.35987271
31Primary immunodeficiency_Homo sapiens_hsa053401.35010158
32Rheumatoid arthritis_Homo sapiens_hsa053231.34989950
33p53 signaling pathway_Homo sapiens_hsa041151.34512165
34Acute myeloid leukemia_Homo sapiens_hsa052211.33722522
35Purine metabolism_Homo sapiens_hsa002301.32367768
36B cell receptor signaling pathway_Homo sapiens_hsa046621.32169450
37Herpes simplex infection_Homo sapiens_hsa051681.30922647
38Small cell lung cancer_Homo sapiens_hsa052221.30243143
39HTLV-I infection_Homo sapiens_hsa051661.30068786
40Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.25979490
41Lysine degradation_Homo sapiens_hsa003101.24920345
42Choline metabolism in cancer_Homo sapiens_hsa052311.21120488
43Viral carcinogenesis_Homo sapiens_hsa052031.20657358
44Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.19173152
45Asthma_Homo sapiens_hsa053101.16098278
46N-Glycan biosynthesis_Homo sapiens_hsa005101.11496925
47Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.11223064
48Intestinal immune network for IgA production_Homo sapiens_hsa046721.09321100
49Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.05020575
50Epstein-Barr virus infection_Homo sapiens_hsa051691.04760485
51Ribosome_Homo sapiens_hsa030101.04643268
52Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.02494117
53Hepatitis B_Homo sapiens_hsa051611.02366315
54Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.00815297
55Hedgehog signaling pathway_Homo sapiens_hsa043401.00019168
56Non-small cell lung cancer_Homo sapiens_hsa052230.99487492
57Pyrimidine metabolism_Homo sapiens_hsa002400.99324739
58Tuberculosis_Homo sapiens_hsa051520.98588419
59Pancreatic cancer_Homo sapiens_hsa052120.98114892
60Antigen processing and presentation_Homo sapiens_hsa046120.96597833
61Thyroid cancer_Homo sapiens_hsa052160.95612424
62Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.94484544
63Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.92290257
64Hippo signaling pathway_Homo sapiens_hsa043900.91708100
65mTOR signaling pathway_Homo sapiens_hsa041500.90502464
66Thyroid hormone signaling pathway_Homo sapiens_hsa049190.90451827
67Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.88852666
68Endometrial cancer_Homo sapiens_hsa052130.87572890
69Bladder cancer_Homo sapiens_hsa052190.86807399
70Basal transcription factors_Homo sapiens_hsa030220.86417273
71Measles_Homo sapiens_hsa051620.86345798
72Neurotrophin signaling pathway_Homo sapiens_hsa047220.84784579
73Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.84491741
74Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.84239359
75Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.83938174
76Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.82384412
77Apoptosis_Homo sapiens_hsa042100.81942031
78Sulfur relay system_Homo sapiens_hsa041220.81435023
79Central carbon metabolism in cancer_Homo sapiens_hsa052300.80950764
80Pathways in cancer_Homo sapiens_hsa052000.79465817
81Systemic lupus erythematosus_Homo sapiens_hsa053220.78084862
82Glycerolipid metabolism_Homo sapiens_hsa005610.77293532
83Oocyte meiosis_Homo sapiens_hsa041140.75935043
84Shigellosis_Homo sapiens_hsa051310.75051142
85Proteoglycans in cancer_Homo sapiens_hsa052050.74449884
86NF-kappa B signaling pathway_Homo sapiens_hsa040640.73112620
87Wnt signaling pathway_Homo sapiens_hsa043100.73067963
88AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.71421678
89TGF-beta signaling pathway_Homo sapiens_hsa043500.71377474
90Leishmaniasis_Homo sapiens_hsa051400.70890774
91T cell receptor signaling pathway_Homo sapiens_hsa046600.70640884
92alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.68704280
932-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.68439169
94Influenza A_Homo sapiens_hsa051640.67552533
95Adherens junction_Homo sapiens_hsa045200.66210787
96Prostate cancer_Homo sapiens_hsa052150.66206639
97Viral myocarditis_Homo sapiens_hsa054160.65357378
98Toxoplasmosis_Homo sapiens_hsa051450.65265882
99Osteoclast differentiation_Homo sapiens_hsa043800.65111262
100Phospholipase D signaling pathway_Homo sapiens_hsa040720.64686803
101Vitamin B6 metabolism_Homo sapiens_hsa007500.64676927
102Hepatitis C_Homo sapiens_hsa051600.63234051
103Adipocytokine signaling pathway_Homo sapiens_hsa049200.62528943
104Glycosaminoglycan degradation_Homo sapiens_hsa005310.60980976
105RNA polymerase_Homo sapiens_hsa030200.60708917
106Toll-like receptor signaling pathway_Homo sapiens_hsa046200.60139021
107Alcoholism_Homo sapiens_hsa050340.59467482
108Circadian rhythm_Homo sapiens_hsa047100.58357024
109Hematopoietic cell lineage_Homo sapiens_hsa046400.57943129
110Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.57252533
111Prolactin signaling pathway_Homo sapiens_hsa049170.57198073
112Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.54939295
113Prion diseases_Homo sapiens_hsa050200.54518416
114VEGF signaling pathway_Homo sapiens_hsa043700.54261036
115Glioma_Homo sapiens_hsa052140.54168988
116PI3K-Akt signaling pathway_Homo sapiens_hsa041510.53905100
117Longevity regulating pathway - mammal_Homo sapiens_hsa042110.52467029
118Platelet activation_Homo sapiens_hsa046110.51949871
119FoxO signaling pathway_Homo sapiens_hsa040680.51493221
120Jak-STAT signaling pathway_Homo sapiens_hsa046300.50430881
121Insulin signaling pathway_Homo sapiens_hsa049100.49259130
122Focal adhesion_Homo sapiens_hsa045100.48720836
123Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.48016262
124Leukocyte transendothelial migration_Homo sapiens_hsa046700.47556727
125Insulin resistance_Homo sapiens_hsa049310.47084035
126Other glycan degradation_Homo sapiens_hsa005110.46760744
127Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.45462403
128MAPK signaling pathway_Homo sapiens_hsa040100.43818966
129RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.43418831
130Legionellosis_Homo sapiens_hsa051340.42708143
131Chemokine signaling pathway_Homo sapiens_hsa040620.39593881
132Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.37540171
133Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.36672390
134Phagosome_Homo sapiens_hsa041450.36638174
135Glutathione metabolism_Homo sapiens_hsa004800.35077829
136NOD-like receptor signaling pathway_Homo sapiens_hsa046210.34483090
137ErbB signaling pathway_Homo sapiens_hsa040120.33367486

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