UQCRFS1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1tricarboxylic acid cycle (GO:0006099)6.36343138
2mitochondrial ATP synthesis coupled proton transport (GO:0042776)6.25296710
3ATP synthesis coupled proton transport (GO:0015986)5.92554033
4energy coupled proton transport, down electrochemical gradient (GO:0015985)5.92554033
5lysine catabolic process (GO:0006554)5.69814133
6lysine metabolic process (GO:0006553)5.69814133
7* respiratory electron transport chain (GO:0022904)5.34864668
8* electron transport chain (GO:0022900)5.20360505
9oxidative phosphorylation (GO:0006119)5.19290644
10mitochondrial electron transport, NADH to ubiquinone (GO:0006120)5.17602746
11regulation of mitochondrial translation (GO:0070129)5.15451561
12fatty acid beta-oxidation (GO:0006635)5.04252092
13cellular ketone body metabolic process (GO:0046950)5.02870647
14ribosomal small subunit biogenesis (GO:0042274)4.85966057
152-oxoglutarate metabolic process (GO:0006103)4.80302547
16regulation of acetyl-CoA biosynthetic process from pyruvate (GO:0010510)4.79778789
17carnitine shuttle (GO:0006853)4.75008937
18branched-chain amino acid catabolic process (GO:0009083)4.73829340
19chaperone-mediated protein transport (GO:0072321)4.71940126
20aspartate family amino acid catabolic process (GO:0009068)4.71530340
21glyoxylate metabolic process (GO:0046487)4.66366847
22fatty acid transmembrane transport (GO:1902001)4.63783948
23NADH metabolic process (GO:0006734)4.63547757
24erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)4.61950390
25L-phenylalanine metabolic process (GO:0006558)4.61950390
26fatty acid oxidation (GO:0019395)4.49028412
27short-chain fatty acid metabolic process (GO:0046459)4.46655997
28fatty acid catabolic process (GO:0009062)4.46086510
29regulation of acyl-CoA biosynthetic process (GO:0050812)4.42555651
30lipid oxidation (GO:0034440)4.41390312
31succinate metabolic process (GO:0006105)4.37606416
32erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)4.36055932
33L-phenylalanine catabolic process (GO:0006559)4.36055932
34ketone body metabolic process (GO:1902224)4.35949906
35branched-chain amino acid metabolic process (GO:0009081)4.34751029
36acetyl-CoA metabolic process (GO:0006084)4.32186114
37maturation of SSU-rRNA (GO:0030490)4.24983337
38deoxyribonucleoside monophosphate metabolic process (GO:0009162)4.23083303
39viral transcription (GO:0019083)4.17413860
40regulation of coenzyme metabolic process (GO:0051196)4.17234146
41regulation of cofactor metabolic process (GO:0051193)4.17234146
42valine metabolic process (GO:0006573)4.16031624
43tricarboxylic acid metabolic process (GO:0072350)4.15639240
44ribosomal small subunit assembly (GO:0000028)4.10941748
45regulation of sequestering of triglyceride (GO:0010889)4.10255407
46pyrimidine deoxyribonucleotide catabolic process (GO:0009223)4.07920473
47sarcomere organization (GO:0045214)4.02339904
48translational termination (GO:0006415)4.00022539
49monocarboxylic acid catabolic process (GO:0072329)3.98623159
50amino-acid betaine metabolic process (GO:0006577)3.96965437
51carnitine metabolic process (GO:0009437)3.95141706
52establishment of protein localization to mitochondrial membrane (GO:0090151)3.92048061
53protein targeting to mitochondrion (GO:0006626)3.91024643
54ribosomal large subunit biogenesis (GO:0042273)3.90528977
55cysteine metabolic process (GO:0006534)3.86659777
56fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540)3.84912384
57ATP biosynthetic process (GO:0006754)3.83531940
58amino-acid betaine transport (GO:0015838)3.80587227
59carnitine transport (GO:0015879)3.80587227
60proteasome assembly (GO:0043248)3.79451684
61carnitine transmembrane transport (GO:1902603)3.77878491
62regulation of fatty acid oxidation (GO:0046320)3.75478660
63mitochondrial respiratory chain complex I assembly (GO:0032981)3.74301107
64NADH dehydrogenase complex assembly (GO:0010257)3.74301107
65mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.74301107
66formation of translation preinitiation complex (GO:0001731)3.72014616
67translational elongation (GO:0006414)3.70846574
68sulfur amino acid catabolic process (GO:0000098)3.70273120
69protein complex biogenesis (GO:0070271)3.69913555
70biotin metabolic process (GO:0006768)3.68418265
71SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.67797064
72aromatic amino acid family catabolic process (GO:0009074)3.67685981
73oxaloacetate metabolic process (GO:0006107)3.64640496
74pyrimidine deoxyribonucleotide metabolic process (GO:0009219)3.62746934
75kynurenine metabolic process (GO:0070189)3.61305732
76nucleobase-containing small molecule interconversion (GO:0015949)3.61061170
77negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.59766921
78establishment of protein localization to mitochondrion (GO:0072655)3.59521197
79cotranslational protein targeting to membrane (GO:0006613)3.59168408
80protein targeting to ER (GO:0045047)3.58987237
81mitochondrial respiratory chain complex assembly (GO:0033108)3.57698069
82triglyceride-rich lipoprotein particle remodeling (GO:0034370)3.52562838
83negative regulation of potassium ion transmembrane transporter activity (GO:1901017)3.51170594
84protein maturation by protein folding (GO:0022417)3.50284839
85regulation of triglyceride catabolic process (GO:0010896)3.49499320
86ethanol oxidation (GO:0006069)3.48982599
87protein localization to endoplasmic reticulum (GO:0070972)3.48573633
88establishment of protein localization to endoplasmic reticulum (GO:0072599)3.48493155
89protein localization to mitochondrion (GO:0070585)3.48073989
90quinone biosynthetic process (GO:1901663)3.47825298
91ubiquinone biosynthetic process (GO:0006744)3.47825298
92translation (GO:0006412)3.47027490
93ribonucleoprotein complex biogenesis (GO:0022613)3.46254760
94regulation of sulfur metabolic process (GO:0042762)3.46108278
95purine nucleotide salvage (GO:0032261)3.42823732
96actin-myosin filament sliding (GO:0033275)3.42430212
97muscle filament sliding (GO:0030049)3.42430212
98alpha-linolenic acid metabolic process (GO:0036109)3.42230929
99organic acid catabolic process (GO:0016054)3.41485387
100carboxylic acid catabolic process (GO:0046395)3.41485387
101mitochondrial transport (GO:0006839)3.41393756
102sarcoplasmic reticulum calcium ion transport (GO:0070296)3.39921324
103pyrimidine nucleoside triphosphate metabolic process (GO:0009147)3.38199108
104cellular component biogenesis (GO:0044085)3.37565554
105pyrimidine nucleotide catabolic process (GO:0006244)3.36107479
106actin-mediated cell contraction (GO:0070252)3.35813096
1072-deoxyribonucleotide biosynthetic process (GO:0009265)3.35634827
108deoxyribose phosphate biosynthetic process (GO:0046385)3.35634827
109translational initiation (GO:0006413)3.35624141
110positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.34596132
111positive regulation of fatty acid oxidation (GO:0046321)3.34291816
112viral life cycle (GO:0019058)3.33562389
113negative regulation of ligase activity (GO:0051352)3.32733932
114negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.32733932
115nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.32552348
116regulation of cellular respiration (GO:0043457)3.30864973
117alpha-amino acid catabolic process (GO:1901606)3.30843561
118serine family amino acid catabolic process (GO:0009071)3.28490274
119cellular amino acid catabolic process (GO:0009063)3.27831281
120regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.27209380
121homocysteine metabolic process (GO:0050667)3.26821835
122negative regulation of potassium ion transmembrane transport (GO:1901380)3.26076572
123quaternary ammonium group transport (GO:0015697)3.25399932
124anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.24791638
125negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471)3.24153000
126metallo-sulfur cluster assembly (GO:0031163)3.20978154
127iron-sulfur cluster assembly (GO:0016226)3.20978154
128cellular protein complex disassembly (GO:0043624)3.20904213
129purine nucleoside triphosphate biosynthetic process (GO:0009145)3.18347507
130positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316)3.17305727
131purine ribonucleoside monophosphate biosynthetic process (GO:0009168)3.16138239
132purine nucleoside monophosphate biosynthetic process (GO:0009127)3.16138239
133response to mercury ion (GO:0046689)3.16111776
134tryptophan catabolic process (GO:0006569)3.14891162
135indole-containing compound catabolic process (GO:0042436)3.14891162
136indolalkylamine catabolic process (GO:0046218)3.14891162
137purine ribonucleoside triphosphate biosynthetic process (GO:0009206)3.14726261
138mitochondrial fusion (GO:0008053)3.14683304
139cardiac myofibril assembly (GO:0055003)3.13697763
140regulation of cellular amino acid metabolic process (GO:0006521)3.12579075
141gluconeogenesis (GO:0006094)3.12520460
142inner mitochondrial membrane organization (GO:0007007)3.10896709
143pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)3.08366398
144cullin deneddylation (GO:0010388)3.06662876
145regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (GO:0010880)3.06277552
146ribonucleoside triphosphate biosynthetic process (GO:0009201)3.05408780
147cardiac muscle contraction (GO:0060048)3.04408991
148bile acid biosynthetic process (GO:0006699)3.03666596
149flavonoid metabolic process (GO:0009812)3.02823275
150acyl-CoA metabolic process (GO:0006637)3.02291450
151thioester metabolic process (GO:0035383)3.02291450
152aerobic respiration (GO:0009060)3.01966642
153DNA strand elongation involved in DNA replication (GO:0006271)3.01818913
154bundle of His cell to Purkinje myocyte communication (GO:0086069)3.01666321
155ubiquinone metabolic process (GO:0006743)3.01334358
156deoxyribonucleoside triphosphate metabolic process (GO:0009200)3.00820702
157guanosine-containing compound biosynthetic process (GO:1901070)3.00100888
158ventricular cardiac muscle cell action potential (GO:0086005)3.00061016
159skeletal muscle contraction (GO:0003009)2.99966918
160IMP metabolic process (GO:0046040)2.99783352
161deoxyribonucleotide catabolic process (GO:0009264)2.99255530
162positive regulation of fatty acid beta-oxidation (GO:0032000)2.99220317
163negative regulation of fatty acid biosynthetic process (GO:0045717)2.98633977
164creatine metabolic process (GO:0006600)2.97825804
165establishment of integrated proviral latency (GO:0075713)2.97801057
166positive regulation of ubiquitin-protein transferase activity (GO:0051443)2.96843272
167protein deneddylation (GO:0000338)2.96189612
168deoxyribose phosphate catabolic process (GO:0046386)2.93483391
169AMP metabolic process (GO:0046033)2.92719084
170DNA strand elongation (GO:0022616)2.92526044
171tryptophan metabolic process (GO:0006568)2.91760259
172nucleoside monophosphate biosynthetic process (GO:0009124)2.91537286
173myofibril assembly (GO:0030239)2.91505099
174deoxyribonucleotide biosynthetic process (GO:0009263)2.90892802
175regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion (GO2.90207072
176dicarboxylic acid metabolic process (GO:0043648)2.89872794
177ribosome biogenesis (GO:0042254)2.89757844
178regulation of skeletal muscle contraction (GO:0014819)2.89612182
179telomere maintenance via semi-conservative replication (GO:0032201)2.89316617

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1PPARG_19300518_ChIP-PET_3T3-L1_Mouse8.90365971
2ESR1_17901129_ChIP-ChIP_LIVER_Mouse7.98438393
3RXR_22158963_ChIP-Seq_LIVER_Mouse5.21995801
4PPARA_22158963_ChIP-Seq_LIVER_Mouse4.86699372
5TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse4.53504490
6* ESRRB_18555785_ChIP-Seq_MESCs_Mouse4.05002957
7LXR_22158963_ChIP-Seq_LIVER_Mouse3.80269265
8E2F7_22180533_ChIP-Seq_HELA_Human3.47512953
9FOXO1_23066095_ChIP-Seq_LIVER_Mouse3.33917621
10EGR1_23403033_ChIP-Seq_LIVER_Mouse3.16558741
11* CEBPA_23403033_ChIP-Seq_LIVER_Mouse3.08270377
12EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.93088594
13THAP11_20581084_ChIP-Seq_MESCs_Mouse2.89841027
14ZNF263_19887448_ChIP-Seq_K562_Human2.54137572
15HNF4A_19761587_ChIP-ChIP_CACO-2_Human2.52476256
16MYC_19079543_ChIP-ChIP_MESCs_Mouse2.49692279
17SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.38652261
18ELF1_17652178_ChIP-ChIP_JURKAT_Human2.26381254
19NR1I2_20693526_ChIP-Seq_LIVER_Mouse2.21050705
20E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.20098589
21MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.04529689
22CLOCK_20551151_ChIP-Seq_293T_Human1.98073172
23* CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.91302214
24TTF2_22483619_ChIP-Seq_HELA_Human1.87312205
25KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.87042173
26FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.84826476
27PPARD_23208498_ChIP-Seq_MDA-MB-231_Human1.80982473
28NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.79980968
29CREB1_15753290_ChIP-ChIP_HEK293T_Human1.79110504
30CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.78941091
31VDR_23849224_ChIP-Seq_CD4+_Human1.77441008
32RARG_19884340_ChIP-ChIP_MEFs_Mouse1.77236556
33FOXP3_21729870_ChIP-Seq_TREG_Human1.75577779
34E2F4_17652178_ChIP-ChIP_JURKAT_Human1.72250472
35BP1_19119308_ChIP-ChIP_Hs578T_Human1.65201337
36* JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.62896764
37STAT3_1855785_ChIP-Seq_MESCs_Mouse1.58484467
38DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.58400481
39* FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.54048723
40POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.52919994
41MYCN_18555785_ChIP-Seq_MESCs_Mouse1.52809790
42GABP_17652178_ChIP-ChIP_JURKAT_Human1.50797826
43SRF_21415370_ChIP-Seq_HL-1_Mouse1.48159516
44YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.47865199
45TCF7L2_21901280_ChIP-Seq_H4IIE_Rat1.43779290
46CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.43326776
47PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.41772269
48FOXM1_23109430_ChIP-Seq_U2OS_Human1.41762827
49MYC_18555785_ChIP-Seq_MESCs_Mouse1.41724134
50HOXB4_20404135_ChIP-ChIP_EML_Mouse1.41372365
51ERG_20887958_ChIP-Seq_HPC-7_Mouse1.40592071
52FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.39853572
53TBX20_22328084_ChIP-Seq_HEART_Mouse1.38217797
54TBX20_22080862_ChIP-Seq_HEART_Mouse1.38217797
55BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.35465805
56E2F1_18555785_ChIP-Seq_MESCs_Mouse1.34007366
57MYC_18358816_ChIP-ChIP_MESCs_Mouse1.33930815
58* CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.33625778
59SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.32664106
60* KDM5A_27292631_Chip-Seq_BREAST_Human1.32181953
61SREBP1_19666523_ChIP-Seq_LIVER_Mouse1.29132155
62CIITA_25753668_ChIP-Seq_RAJI_Human1.28215659
63ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.27903657
64* ETS1_20019798_ChIP-Seq_JURKAT_Human1.27870794
65POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.26785727
66NANOG_18555785_ChIP-Seq_MESCs_Mouse1.24664935
67KLF4_18555785_ChIP-Seq_MESCs_Mouse1.24242956
68SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.23422162
69E2F1_21310950_ChIP-Seq_MCF-7_Human1.22954259
70E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.16540413
71STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.15820739
72DCP1A_22483619_ChIP-Seq_HELA_Human1.14937369
73CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.14654792
74* CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.13519555
75MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.13216430
76GATA4_21415370_ChIP-Seq_HL-1_Mouse1.12552367
77AR_21909140_ChIP-Seq_LNCAP_Human1.11105721
78SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.11002325
79ELK1_19687146_ChIP-ChIP_HELA_Human1.10076776
80TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.08046811
81* ZFX_18555785_ChIP-Seq_MESCs_Mouse1.07829371
82VDR_21846776_ChIP-Seq_THP-1_Human1.07786937
83TRIM28_19339689_ChIP-ChIP_MESCs_Mouse1.05121691
84GATA1_22025678_ChIP-Seq_K562_Human1.04661507
85EP300_21415370_ChIP-Seq_HL-1_Mouse1.02817381
86MEF2A_21415370_ChIP-Seq_HL-1_Mouse1.02289323
87SRY_22984422_ChIP-ChIP_TESTIS_Rat1.01932529
88THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse0.99650410
89TFEB_21752829_ChIP-Seq_HELA_Human0.99025598
90RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.98293845
91CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.97519917
92GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.96388664
93KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.96256132
94CTCF_18555785_ChIP-Seq_MESCs_Mouse0.94699565
95YY1_22570637_ChIP-Seq_MALME-3M_Human0.94308832
96MYCN_21190229_ChIP-Seq_SHEP-21N_Human0.94179543
97EST1_17652178_ChIP-ChIP_JURKAT_Human0.92617716
98SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.91978178
99* SOX2_27498859_Chip-Seq_STOMACH_Mouse0.90526072
100TBX5_21415370_ChIP-Seq_HL-1_Mouse0.89977350
101PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse0.89781594
102* CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.89023687
103ATF3_27146783_Chip-Seq_COLON_Human0.88815979
104HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.88441916
105DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.88330191
106YY1_21170310_ChIP-Seq_MESCs_Mouse0.88328304
107KLF4_18358816_ChIP-ChIP_MESCs_Mouse0.87715520
108NKX2-5_21415370_ChIP-Seq_HL-1_Mouse0.87397183
109TET1_21451524_ChIP-Seq_MESCs_Mouse0.86612419
110NOTCH1_17114293_ChIP-ChIP_T-ALL_Human0.85734471
111HCFC1_20581084_ChIP-Seq_MESCs_Mouse0.83724207
112ELF1_20517297_ChIP-Seq_JURKAT_Human0.82750653
113BCL6_27268052_Chip-Seq_Bcells_Human0.82284836
114* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.82265422
115OCT4_18692474_ChIP-Seq_MEFs_Mouse0.81164023
116HNF4A_19822575_ChIP-Seq_HepG2_Human0.80769710
117BCOR_27268052_Chip-Seq_Bcells_Human0.80292067
118TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat0.79018367
119SMAD2/3_21741376_ChIP-Seq_ESCs_Human0.78892845
120SOX2_18692474_ChIP-Seq_MEFs_Mouse0.78782151
121NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human0.78660098
122LXR_22292898_ChIP-Seq_THP-1_Human0.78648139
123SREBP2_21459322_ChIP-Seq_LIVER_Mouse0.77725990
124AUTS2_25519132_ChIP-Seq_293T-REX_Human0.77309524
125RXRA_24833708_ChIP-Seq_LIVER_Mouse0.76642579
126ESR1_20079471_ChIP-ChIP_T-47D_Human0.76638198
127EGR1_19032775_ChIP-ChIP_M12_Human0.76594019
128BMI1_19503595_ChIP-Seq_MEFsC_Mouse0.76568476
129GATA4_25053715_ChIP-Seq_YYC3_Human0.75863857
130ZFP42_18358816_ChIP-ChIP_MESCs_Mouse0.75707671
131FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse0.75039153
132MYC_19030024_ChIP-ChIP_MESCs_Mouse0.74902913
133RAD21_21589869_ChIP-Seq_MESCs_Mouse0.74710252
134TAF2_19829295_ChIP-Seq_ESCs_Human0.73579198
135CTCF_26484167_Chip-Seq_Bcells_Mouse0.73467475
136HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human0.73136447
137SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.72645978
138P68_20966046_ChIP-Seq_HELA_Human0.71415401
139* CHD1_19587682_ChIP-ChIP_MESCs_Mouse0.71363610
140* CTCF_21964334_Chip-Seq_Bcells_Human0.71093498
141GATA3_20176728_ChIP-ChIP_TSCs_Mouse0.71050928
142NANOG_20526341_ChIP-Seq_ESCs_Human0.70696198
143XRN2_22483619_ChIP-Seq_HELA_Human0.70043168
144FOXP1_21924763_ChIP-Seq_HESCs_Human0.69473987
145RACK7_27058665_Chip-Seq_MCF-7_Human0.68977138
146* GABP_19822575_ChIP-Seq_HepG2_Human0.68081943
147NELFA_20434984_ChIP-Seq_ESCs_Mouse0.67468422
148TAL1_20887958_ChIP-Seq_HPC-7_Mouse0.66719497
149ERG_20517297_ChIP-Seq_VCAP_Human0.66623419

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005360_urolithiasis4.61555967
2MP0003646_muscle_fatigue4.56559620
3MP0002139_abnormal_hepatobiliary_system4.41101216
4MP0002837_dystrophic_cardiac_calcinosis4.40318568
5MP0005085_abnormal_gallbladder_physiolo3.75913118
6MP0003806_abnormal_nucleotide_metabolis3.64465504
7MP0005365_abnormal_bile_salt3.37293358
8MP0004084_abnormal_cardiac_muscle3.16398121
9MP0004215_abnormal_myocardial_fiber3.13248788
10MP0000751_myopathy3.10671822
11MP0006036_abnormal_mitochondrial_physio3.10415815
12MP0003693_abnormal_embryo_hatching2.99894362
13MP0005330_cardiomyopathy2.91465737
14MP0008875_abnormal_xenobiotic_pharmacok2.73627424
15MP0000749_muscle_degeneration2.69512323
16MP0004036_abnormal_muscle_relaxation2.67049807
17MP0004130_abnormal_muscle_cell2.65706280
18MP0005332_abnormal_amino_acid2.58575884
19MP0009379_abnormal_foot_pigmentation2.54349088
20MP0004957_abnormal_blastocyst_morpholog2.43972324
21MP0003195_calcinosis2.41383290
22MP0003111_abnormal_nucleus_morphology2.41195690
23MP0010094_abnormal_chromosome_stability2.31426323
24MP0009840_abnormal_foam_cell2.14049932
25MP0008058_abnormal_DNA_repair2.09913286
26MP0008932_abnormal_embryonic_tissue2.09212846
27MP0004043_abnormal_pH_regulation2.07027411
28MP0010329_abnormal_lipoprotein_level2.01535002
29MP0004087_abnormal_muscle_fiber1.99884197
30MP0006035_abnormal_mitochondrial_morpho1.99848008
31MP0002972_abnormal_cardiac_muscle1.97035787
32MP0005083_abnormal_biliary_tract1.96245078
33MP0003252_abnormal_bile_duct1.93104302
34MP0003077_abnormal_cell_cycle1.87929725
35MP0005666_abnormal_adipose_tissue1.85406495
36MP0008775_abnormal_heart_ventricle1.85173310
37MP0003221_abnormal_cardiomyocyte_apopto1.83186816
38MP0005670_abnormal_white_adipose1.82458429
39MP0005620_abnormal_muscle_contractility1.81421962
40MP0003137_abnormal_impulse_conducting1.77152803
41MP0002269_muscular_atrophy1.77051914
42MP0005385_cardiovascular_system_phenoty1.73884989
43MP0001544_abnormal_cardiovascular_syste1.73884989
44MP0001666_abnormal_nutrient_absorption1.73673696
45MP0003186_abnormal_redox_activity1.71403208
46MP0000750_abnormal_muscle_regeneration1.70805003
47MP0005319_abnormal_enzyme/_coenzyme1.68217552
48MP0000747_muscle_weakness1.63029081
49MP0008007_abnormal_cellular_replicative1.62711067
50MP0002106_abnormal_muscle_physiology1.61713903
51MP0002118_abnormal_lipid_homeostasis1.60512494
52MP0005584_abnormal_enzyme/coenzyme_acti1.60500556
53MP0005451_abnormal_body_composition1.56049641
54MP0001529_abnormal_vocalization1.54517609
55MP0009643_abnormal_urine_homeostasis1.53440751
56MP0004484_altered_response_of1.53150908
57MP0010630_abnormal_cardiac_muscle1.44434709
58MP0003786_premature_aging1.43065716
59MP0002332_abnormal_exercise_endurance1.42774725
60MP0002971_abnormal_brown_adipose1.40938902
61MP0001727_abnormal_embryo_implantation1.39259752
62MP0006138_congestive_heart_failure1.39022552
63MP0004145_abnormal_muscle_electrophysio1.37635181
64MP0005266_abnormal_metabolism1.36032750
65MP0004019_abnormal_vitamin_homeostasis1.34821692
66MP0000609_abnormal_liver_physiology1.34124919
67MP0003191_abnormal_cellular_cholesterol1.32980793
68MP0001661_extended_life_span1.31102680
69MP0002138_abnormal_hepatobiliary_system1.30511987
70MP0000759_abnormal_skeletal_muscle1.26922613
71MP0003123_paternal_imprinting1.22414495
72MP0003315_abnormal_perineum_morphology1.21391382
73MP0008260_abnormal_autophagy1.21302240
74MP0005369_muscle_phenotype1.20833615
75MP0005636_abnormal_mineral_homeostasis1.20802529
76MP0005535_abnormal_body_temperature1.14913174
77MP0001764_abnormal_homeostasis1.13639720
78MP0003718_maternal_effect1.13086209
79MP0004185_abnormal_adipocyte_glucose1.12967407
80MP0003656_abnormal_erythrocyte_physiolo1.12452861
81MP0000372_irregular_coat_pigmentation1.11385920
82MP0001730_embryonic_growth_arrest1.11161894
83MP0002822_catalepsy1.10591086
84MP0002078_abnormal_glucose_homeostasis1.09881776
85MP0002163_abnormal_gland_morphology1.09560714
86MP0004233_abnormal_muscle_weight1.09120662
87MP0005375_adipose_tissue_phenotype1.07963095
88MP0004085_abnormal_heartbeat1.07849424
89MP0004147_increased_porphyrin_level1.07808651
90MP0005058_abnormal_lysosome_morphology1.06922568
91MP0001756_abnormal_urination1.02077864
92MP0000313_abnormal_cell_death0.99049797
93MP0000230_abnormal_systemic_arterial0.98642695
94MP0003828_pulmonary_edema0.98020950
95MP0005165_increased_susceptibility_to0.93727335
96MP0002877_abnormal_melanocyte_morpholog0.93384160
97MP0000350_abnormal_cell_proliferation0.91978088
98MP0002127_abnormal_cardiovascular_syste0.84614674
99MP0009333_abnormal_splenocyte_physiolog0.84595422
100MP0000343_altered_response_to0.80447452
101MP0003567_abnormal_fetal_cardiomyocyte0.79912085
102MP0005501_abnormal_skin_physiology0.78948893
103MP0001765_abnormal_ion_homeostasis0.78002809
104MP0005376_homeostasis/metabolism_phenot0.77974477
105MP0005084_abnormal_gallbladder_morpholo0.77448273
106MP0000733_abnormal_muscle_development0.77331660
107MP0002080_prenatal_lethality0.76548152
108MP0005334_abnormal_fat_pad0.76505342
109MP0002160_abnormal_reproductive_system0.73735217
110MP0001905_abnormal_dopamine_level0.73545676
111MP0000013_abnormal_adipose_tissue0.71378645
112MP0009642_abnormal_blood_homeostasis0.70153691
113MP0000598_abnormal_liver_morphology0.68604488
114MP0008789_abnormal_olfactory_epithelium0.68438539
115MP0003941_abnormal_skin_development0.68419699
116MP0001697_abnormal_embryo_size0.66691665
117MP0009672_abnormal_birth_weight0.62208760
118MP0006276_abnormal_autonomic_nervous0.61831505
119MP0005379_endocrine/exocrine_gland_phen0.60901183
120MP0002234_abnormal_pharynx_morphology0.58761526
121MP0005380_embryogenesis_phenotype0.58318690
122MP0001672_abnormal_embryogenesis/_devel0.58318690
123MP0003011_delayed_dark_adaptation0.58263150
124MP0005448_abnormal_energy_balance0.57465955
125MP0002970_abnormal_white_adipose0.56075865
126MP0002132_abnormal_respiratory_system0.55640511
127MP0009763_increased_sensitivity_to0.54952014
128MP0000490_abnormal_crypts_of0.54666862
129MP0003705_abnormal_hypodermis_morpholog0.54394036
130MP0002019_abnormal_tumor_incidence0.54277477
131MP0008469_abnormal_protein_level0.53016940
132MP0000358_abnormal_cell_content/0.52478741
133MP0003868_abnormal_feces_composition0.52323756
134MP0001881_abnormal_mammary_gland0.52029563
135MP0003329_amyloid_beta_deposits0.51064968
136MP0002136_abnormal_kidney_physiology0.50856227
137MP0000003_abnormal_adipose_tissue0.50117354
138MP0001853_heart_inflammation0.49966080
139MP0009697_abnormal_copulation0.49682918
140MP0003959_abnormal_lean_body0.49322658
141MP0003953_abnormal_hormone_level0.49079606
142MP0000266_abnormal_heart_morphology0.48356990
143MP0009115_abnormal_fat_cell0.46630746
144MP0005452_abnormal_adipose_tissue0.46154365

Predicted human phenotypes

RankGene SetZ-score
1Muscle fiber inclusion bodies (HP:0100299)5.87977623
2Nemaline bodies (HP:0003798)5.78284321
3Muscle fiber cytoplasmatic inclusion bodies (HP:0100303)5.69024849
4Myoglobinuria (HP:0002913)4.64831131
5Hypoglycemic coma (HP:0001325)4.50823342
6Hepatic necrosis (HP:0002605)4.46582726
7Abnormal mitochondria in muscle tissue (HP:0008316)4.35946980
8Acute encephalopathy (HP:0006846)4.33716855
9Abnormality of fatty-acid metabolism (HP:0004359)4.32662249
10Acute necrotizing encephalopathy (HP:0006965)4.28461957
11Ketoacidosis (HP:0001993)4.25674790
12Cerebral edema (HP:0002181)4.16394835
13Hyperglycinuria (HP:0003108)4.15232191
14Abnormality of dicarboxylic acid metabolism (HP:0010995)4.12298289
15Dicarboxylic aciduria (HP:0003215)4.12298289
16Sudden death (HP:0001699)4.02050170
17Ketosis (HP:0001946)3.99987982
18Hyperammonemia (HP:0001987)3.96833783
19Rhabdomyolysis (HP:0003201)3.92359274
20Exercise-induced myalgia (HP:0003738)3.87122403
21Hepatocellular necrosis (HP:0001404)3.77178878
22Increased muscle lipid content (HP:0009058)3.72921122
23Myopathic facies (HP:0002058)3.69727304
24Exercise-induced muscle cramps (HP:0003710)3.68319275
25Abnormality of glycine metabolism (HP:0010895)3.67056675
26Abnormality of serine family amino acid metabolism (HP:0010894)3.67056675
27Mitochondrial inheritance (HP:0001427)3.64203677
28Progressive muscle weakness (HP:0003323)3.60193682
29Generalized aminoaciduria (HP:0002909)3.52559568
30Progressive macrocephaly (HP:0004481)3.51596081
31Increased CSF lactate (HP:0002490)3.51388177
32Abnormality of aromatic amino acid family metabolism (HP:0004338)3.51111204
33Type 1 muscle fiber predominance (HP:0003803)3.50409569
34Ventricular tachycardia (HP:0004756)3.40688045
35Lactic acidosis (HP:0003128)3.40495695
36Palpitations (HP:0001962)3.37231368
37Increased intramyocellular lipid droplets (HP:0012240)3.34046574
38Calf muscle hypertrophy (HP:0008981)3.33969338
39Abnormality of glycolysis (HP:0004366)3.33561372
40Increased serum pyruvate (HP:0003542)3.33561372
41Abnormality of long-chain fatty-acid metabolism (HP:0010964)3.27849458
42Rimmed vacuoles (HP:0003805)3.27216216
43Centrally nucleated skeletal muscle fibers (HP:0003687)3.26910921
44Lethargy (HP:0001254)3.25972476
45Hyperglycinemia (HP:0002154)3.22056837
46Decreased activity of mitochondrial respiratory chain (HP:0008972)3.20273028
47Abnormal activity of mitochondrial respiratory chain (HP:0011922)3.20273028
48Muscle hypertrophy of the lower extremities (HP:0008968)3.18826314
49Microvesicular hepatic steatosis (HP:0001414)3.13672590
50Lipid accumulation in hepatocytes (HP:0006561)3.02273712
51Abnormality of alanine metabolism (HP:0010916)3.02235160
52Hyperalaninemia (HP:0003348)3.02235160
53Abnormality of pyruvate family amino acid metabolism (HP:0010915)3.02235160
54Ragged-red muscle fibers (HP:0003200)3.01319154
55Xanthomatosis (HP:0000991)2.93009134
56Metabolic acidosis (HP:0001942)2.92977127
57Nausea (HP:0002018)2.90420586
58Renal Fanconi syndrome (HP:0001994)2.89106282
59Distal arthrogryposis (HP:0005684)2.86737473
60Proximal tubulopathy (HP:0000114)2.81599888
61Intrahepatic cholestasis (HP:0001406)2.78445478
62Lipoatrophy (HP:0100578)2.78364249
63Muscle fiber splitting (HP:0003555)2.78355895
64Exercise intolerance (HP:0003546)2.76794424
65Respiratory failure (HP:0002878)2.76327609
66Vomiting (HP:0002013)2.69999791
67Neck muscle weakness (HP:0000467)2.68717737
68Gout (HP:0001997)2.67947662
69Increased serum lactate (HP:0002151)2.65459321
70Abnormality of urine glucose concentration (HP:0011016)2.64360826
71Glycosuria (HP:0003076)2.64360826
72Abnormality of serum amino acid levels (HP:0003112)2.63731861
73Right ventricular cardiomyopathy (HP:0011663)2.60447267
74Dilated cardiomyopathy (HP:0001644)2.57972133
75Conjunctival hamartoma (HP:0100780)2.55678225
76Hyperlipoproteinemia (HP:0010980)2.53980959
77Hypoalphalipoproteinemia (HP:0003233)2.52544011
78Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.51189104
79Muscle stiffness (HP:0003552)2.50323436
80Syncope (HP:0001279)2.49451423
81Abnormality of the calf musculature (HP:0001430)2.49067766
82Increased hepatocellular lipid droplets (HP:0006565)2.48395675
83Calcaneovalgus deformity (HP:0001848)2.47234046
84Hypobetalipoproteinemia (HP:0003563)2.43941479
85Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.42661839
86Abnormality of cells of the erythroid lineage (HP:0012130)2.42053522
87Methylmalonic aciduria (HP:0012120)2.41467090
88Hypolipoproteinemia (HP:0010981)2.41356065
89Distal lower limb muscle weakness (HP:0009053)2.41168952
90Atrial fibrillation (HP:0005110)2.39013270
91Asymmetric septal hypertrophy (HP:0001670)2.37584331
92Pheochromocytoma (HP:0002666)2.36054809
93Abnormality of glutamine family amino acid metabolism (HP:0010902)2.34508051
943-Methylglutaconic aciduria (HP:0003535)2.33951156
95Abnormality of monocarboxylic acid metabolism (HP:0010996)2.33210206
96CNS demyelination (HP:0007305)2.26728967
97Macrocytic anemia (HP:0001972)2.25484784
98Deep venous thrombosis (HP:0002625)2.24996175
99Hyporeflexia of lower limbs (HP:0002600)2.24158030
100Primary atrial arrhythmia (HP:0001692)2.23953678
101Respiratory difficulties (HP:0002880)2.23152708
102Supraventricular tachycardia (HP:0004755)2.22909110
103Multiple enchondromatosis (HP:0005701)2.22566511
104Neuroendocrine neoplasm (HP:0100634)2.22434774
105Myotonia (HP:0002486)2.21899870
106Reduced antithrombin III activity (HP:0001976)2.21755071
107Type I transferrin isoform profile (HP:0003642)2.21624090
108Abnormality of aspartate family amino acid metabolism (HP:0010899)2.21486980
109Abnormality of the level of lipoprotein cholesterol (HP:0010979)2.21384684
110Deformed tarsal bones (HP:0008119)2.20199498
111EMG: myopathic abnormalities (HP:0003458)2.18452804
112Ventricular arrhythmia (HP:0004308)2.18001110
113Abnormal number of erythroid precursors (HP:0012131)2.17662937
114Reticulocytopenia (HP:0001896)2.17241406
115Hyperuricemia (HP:0002149)2.16613478
116Increased purine levels (HP:0004368)2.16613478
117Late onset (HP:0003584)2.16467743
118Supraventricular arrhythmia (HP:0005115)2.16460880
119Emotional lability (HP:0000712)2.13554176
120Abnormality of purine metabolism (HP:0004352)2.13369599
121Cerebral hypomyelination (HP:0006808)2.09632293
122Leukodystrophy (HP:0002415)2.07301339
123Bundle branch block (HP:0011710)2.07235141
124Aplasia/Hypoplasia of the sacrum (HP:0008517)2.06722470
125Delayed CNS myelination (HP:0002188)2.05685915
126Hyperinsulinemic hypoglycemia (HP:0000825)2.05353132
127Abnormality of skeletal muscle fiber size (HP:0012084)2.05066027
128Neoplasm of the adrenal gland (HP:0100631)2.03645185
129Aplastic anemia (HP:0001915)2.01347924
130Subaortic stenosis (HP:0001682)1.98682405
131Abnormality of the left ventricular outflow tract (HP:0011103)1.98682405
132Heart block (HP:0012722)1.97167588
133Cerebral palsy (HP:0100021)1.96991522
134Prolonged QT interval (HP:0001657)1.96861355
135Degeneration of anterior horn cells (HP:0002398)1.90713721
136Abnormality of the anterior horn cell (HP:0006802)1.90713721
137Increased connective tissue (HP:0009025)1.89225568
138Exertional dyspnea (HP:0002875)1.87336395
139Limb-girdle muscle atrophy (HP:0003797)1.86860609
140Areflexia of lower limbs (HP:0002522)1.85981393
141Paralysis (HP:0003470)1.85633038
142Shoulder girdle muscle weakness (HP:0003547)1.83837148
143Round ear (HP:0100830)1.82730392
144Distal lower limb amyotrophy (HP:0008944)1.80687054
145Testicular atrophy (HP:0000029)1.78345960
146Muscle fiber atrophy (HP:0100295)1.78325706
147Abnormality of the tricuspid valve (HP:0001702)1.78322931
148Bulbar palsy (HP:0001283)1.78288362

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BCKDK6.15571684
2PDK43.96481313
3PDK33.96481313
4OBSCN3.70756786
5BUB13.48488697
6TTN3.37318290
7VRK23.17308096
8PHKG23.13478716
9PHKG13.13478716
10LMTK23.05665616
11NME22.96489359
12TRIB32.95730962
13PKN22.84839041
14NEK12.76800370
15MYLK2.59879967
16PINK12.45306265
17WNK42.30816528
18PDK22.30231779
19SRPK12.03264188
20PIM21.89115371
21PBK1.77212894
22CDK191.63624866
23CDC71.59862737
24NME11.58666444
25MAP3K121.54700701
26STK241.49214587
27PIK3CA1.38584340
28NEK91.38194312
29FLT31.32014965
30STK38L1.31880444
31MAP3K111.31643205
32CCNB11.25518692
33TIE11.23886082
34CSNK1G31.23113042
35WNK31.23060140
36AURKA1.22749070
37EIF2AK11.22482944
38MAP2K31.21186071
39ERN11.17898226
40MAPKAPK31.16131793
41MUSK1.15635321
42KDR1.12674749
43PIK3CG1.10075274
44DAPK11.06668348
45MAP3K51.03374015
46ILK1.03344161
47VRK11.02527409
48TTK0.97874824
49PLK40.95392083
50MST1R0.94461991
51INSRR0.94241940
52PLK10.94192821
53AURKB0.93895246
54STK390.93216410
55CAMK2D0.92728002
56ABL20.89500101
57GRK70.89313226
58DMPK0.87881442
59MAPK110.87060208
60MAP2K60.85516465
61MAP2K40.81927425
62PRKAA20.81872967
63MAPK120.81721886
64SIK10.81027298
65CSNK1G10.80807836
66CSNK1G20.80191077
67CAMK2G0.79964357
68FGFR40.77348866
69LIMK10.75374904
70CSNK1A1L0.74661356
71PRKAA10.73880930
72CHEK20.73339761
73RPS6KB20.72956239
74MAP2K70.70988707
75MAP3K70.70556762
76DAPK30.70386228
77SMG10.68419032
78TESK20.68001743
79CDK80.68000943
80PAK30.67558403
81RPS6KA50.67252284
82MAP3K30.64283527
83CDK140.63484050
84STK160.63163541
85PAK10.62906549
86ARAF0.62061872
87PRKD10.58523275
88CDK11A0.58319691
89ATR0.56315510
90RAF10.55716299
91BRSK10.55689507
92CSNK2A20.55337335
93PDPK10.55117693
94PAK40.54585504
95TAOK20.53267828
96CDK150.52072157
97PRKACG0.49504917
98DYRK20.49339798
99MAP2K20.48968838
100MAP2K10.48825232
101KSR20.48686764
102CSNK2A10.48344214
103CDK70.48158577
104CDK180.47658824
105MOS0.47214122
106AKT20.47063785
107TBK10.46392088
108DYRK30.44705828
109LRRK20.43421449
110PDK10.42110119
111OXSR10.41424179
112CHEK10.38434205
113EEF2K0.37875282
114PRKACA0.35629979
115TESK10.35332019
116ERBB30.35299078
117DYRK1B0.34721900
118PRKG20.33382849
119MAPKAPK50.32336344
120PRKCI0.31804145
121BRAF0.29994134
122IRAK10.29825253
123CAMK2A0.29383377
124STK40.29324474
125PTK60.28862093
126JAK20.26631565
127TYK20.25774904
128GRK60.25397657
129ROCK10.25011471
130MAPK40.24890600
131IRAK30.24729054
132PLK30.21926305
133PRKACB0.21785551
134CDK20.20651231
135MAP3K10.20456540
136STK380.20147240
137PIM10.20135264
138SCYL20.18419870
139EIF2AK30.18088237
140ZAK0.13882462
141RPS6KA10.13677246
142MAP3K80.12929126
143CAMK40.12233075
144TLK10.11615376
145CDK40.10487280
146RPS6KA40.10086847
147ERBB40.09629300
148PRKCA0.08900458

Predicted pathways (KEGG)

RankGene SetZ-score
1Citrate cycle (TCA cycle)_Homo sapiens_hsa000204.33663727
2Propanoate metabolism_Homo sapiens_hsa006403.60230344
32-Oxocarboxylic acid metabolism_Homo sapiens_hsa012103.41155156
4Valine, leucine and isoleucine degradation_Homo sapiens_hsa002803.32053341
5Fatty acid degradation_Homo sapiens_hsa000713.29170044
6Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006302.97779661
7DNA replication_Homo sapiens_hsa030302.92748124
8* Oxidative phosphorylation_Homo sapiens_hsa001902.89170061
9Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004002.80272079
10Parkinsons disease_Homo sapiens_hsa050122.78763436
11Carbon metabolism_Homo sapiens_hsa012002.48241908
12Fatty acid metabolism_Homo sapiens_hsa012122.45197979
13Butanoate metabolism_Homo sapiens_hsa006502.40142934
14Pyruvate metabolism_Homo sapiens_hsa006202.29662567
15Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.26375564
16Base excision repair_Homo sapiens_hsa034102.11280170
17Primary bile acid biosynthesis_Homo sapiens_hsa001202.05024214
18Tryptophan metabolism_Homo sapiens_hsa003801.96190486
19Mismatch repair_Homo sapiens_hsa034301.95906509
20* Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.92003122
21Alzheimers disease_Homo sapiens_hsa050101.91317440
22* Cardiac muscle contraction_Homo sapiens_hsa042601.88868976
23Peroxisome_Homo sapiens_hsa041461.87968003
24RNA polymerase_Homo sapiens_hsa030201.87851679
25Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.82817366
26PPAR signaling pathway_Homo sapiens_hsa033201.78786436
27Arginine biosynthesis_Homo sapiens_hsa002201.78590093
28Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.75850920
29Sulfur metabolism_Homo sapiens_hsa009201.71712913
30Nitrogen metabolism_Homo sapiens_hsa009101.70609345
31Huntingtons disease_Homo sapiens_hsa050161.69798997
32Fatty acid elongation_Homo sapiens_hsa000621.66846660
33Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.65173274
34beta-Alanine metabolism_Homo sapiens_hsa004101.62937434
35Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.61624468
36Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.54871551
37Spliceosome_Homo sapiens_hsa030401.53297047
38Biosynthesis of amino acids_Homo sapiens_hsa012301.52835697
39Pentose and glucuronate interconversions_Homo sapiens_hsa000401.45727210
40Nucleotide excision repair_Homo sapiens_hsa034201.44587849
41Glycolysis / Gluconeogenesis_Homo sapiens_hsa000101.44441502
42Starch and sucrose metabolism_Homo sapiens_hsa005001.30980983
43Folate biosynthesis_Homo sapiens_hsa007901.21134723
44RNA transport_Homo sapiens_hsa030131.17305076
45Cysteine and methionine metabolism_Homo sapiens_hsa002701.15500775
46Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.14075002
47Phenylalanine metabolism_Homo sapiens_hsa003601.13203266
48Fat digestion and absorption_Homo sapiens_hsa049751.12531508
49Sulfur relay system_Homo sapiens_hsa041221.10300419
50Purine metabolism_Homo sapiens_hsa002301.08491637
51Homologous recombination_Homo sapiens_hsa034401.06324759
52Arginine and proline metabolism_Homo sapiens_hsa003301.05607760
53Selenocompound metabolism_Homo sapiens_hsa004501.03067815
54Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.00300121
55Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.97520152
56Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.97510194
57Chemical carcinogenesis_Homo sapiens_hsa052040.96526376
58Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.96410849
59Drug metabolism - other enzymes_Homo sapiens_hsa009830.92783113
60Tyrosine metabolism_Homo sapiens_hsa003500.91277722
61Pentose phosphate pathway_Homo sapiens_hsa000300.89188707
62Bile secretion_Homo sapiens_hsa049760.85673006
63Histidine metabolism_Homo sapiens_hsa003400.84169972
64Glutathione metabolism_Homo sapiens_hsa004800.82559059
65Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.81515858
66Fructose and mannose metabolism_Homo sapiens_hsa000510.78072582
67* Metabolic pathways_Homo sapiens_hsa011000.76313830
68Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.74570626
69Complement and coagulation cascades_Homo sapiens_hsa046100.73948170
70Cell cycle_Homo sapiens_hsa041100.72595838
71RNA degradation_Homo sapiens_hsa030180.72069195
72Galactose metabolism_Homo sapiens_hsa000520.71661721
73Caffeine metabolism_Homo sapiens_hsa002320.68720231
74Glycerolipid metabolism_Homo sapiens_hsa005610.67561283
75Fanconi anemia pathway_Homo sapiens_hsa034600.67186564
76Fatty acid biosynthesis_Homo sapiens_hsa000610.65796517
77Retinol metabolism_Homo sapiens_hsa008300.64417439
78Cyanoamino acid metabolism_Homo sapiens_hsa004600.64101695
79Proteasome_Homo sapiens_hsa030500.60727793
80Non-homologous end-joining_Homo sapiens_hsa034500.59266646
81Steroid hormone biosynthesis_Homo sapiens_hsa001400.57841724
82Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.57543890
83Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.56816654
84Collecting duct acid secretion_Homo sapiens_hsa049660.54625549
85Vibrio cholerae infection_Homo sapiens_hsa051100.54377194
86Dilated cardiomyopathy_Homo sapiens_hsa054140.54132231
87Ribosome_Homo sapiens_hsa030100.52967691
88Systemic lupus erythematosus_Homo sapiens_hsa053220.52428803
89Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.51477860
90Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.49570379
91Adipocytokine signaling pathway_Homo sapiens_hsa049200.49429264
92Glucagon signaling pathway_Homo sapiens_hsa049220.42663444
93Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.42441365
94Lysine degradation_Homo sapiens_hsa003100.40835889
95Maturity onset diabetes of the young_Homo sapiens_hsa049500.40794354
96Insulin resistance_Homo sapiens_hsa049310.39766478
97ABC transporters_Homo sapiens_hsa020100.38878682
98Oocyte meiosis_Homo sapiens_hsa041140.36731706
99Vitamin digestion and absorption_Homo sapiens_hsa049770.35522049
100Basal transcription factors_Homo sapiens_hsa030220.33539448
101Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.33165530
102Epstein-Barr virus infection_Homo sapiens_hsa051690.32651889
103mRNA surveillance pathway_Homo sapiens_hsa030150.29577961
104Synaptic vesicle cycle_Homo sapiens_hsa047210.29152870
105Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.29100018
106AMPK signaling pathway_Homo sapiens_hsa041520.28443879
107Insulin signaling pathway_Homo sapiens_hsa049100.28046802
108Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.26734383
109N-Glycan biosynthesis_Homo sapiens_hsa005100.22240132
110Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.21543334
111Vitamin B6 metabolism_Homo sapiens_hsa007500.19689226
112alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.19453316
113Alcoholism_Homo sapiens_hsa050340.19342411
114Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.17307954
115Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.16345348
116One carbon pool by folate_Homo sapiens_hsa006700.15205763
117Linoleic acid metabolism_Homo sapiens_hsa005910.13196006
118p53 signaling pathway_Homo sapiens_hsa041150.13037417
119Pyrimidine metabolism_Homo sapiens_hsa002400.11298357
120Shigellosis_Homo sapiens_hsa051310.10612722
121Staphylococcus aureus infection_Homo sapiens_hsa051500.09466696
122Glycerophospholipid metabolism_Homo sapiens_hsa005640.08159516
123Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.06654917
124Central carbon metabolism in cancer_Homo sapiens_hsa052300.05978356
125Viral myocarditis_Homo sapiens_hsa054160.02746033
126Steroid biosynthesis_Homo sapiens_hsa001000.02097015
127Protein export_Homo sapiens_hsa030600.01045316
128Regulation of autophagy_Homo sapiens_hsa041400.00387369
129HIF-1 signaling pathway_Homo sapiens_hsa04066-0.0604673
130Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970-0.0390411
131Arachidonic acid metabolism_Homo sapiens_hsa00590-0.0341922

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