

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | deoxyribonucleoside monophosphate metabolic process (GO:0009162) | 4.86639877 |
| 2 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 4.81713049 |
| 3 | ATP synthesis coupled proton transport (GO:0015986) | 4.48202430 |
| 4 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 4.48202430 |
| 5 | metallo-sulfur cluster assembly (GO:0031163) | 4.47215065 |
| 6 | iron-sulfur cluster assembly (GO:0016226) | 4.47215065 |
| 7 | regulation of mitochondrial translation (GO:0070129) | 4.28207944 |
| 8 | proteasome assembly (GO:0043248) | 4.15647900 |
| 9 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 4.09461977 |
| 10 | establishment of viral latency (GO:0019043) | 4.08112292 |
| 11 | respiratory electron transport chain (GO:0022904) | 4.03733208 |
| 12 | DNA deamination (GO:0045006) | 4.03050807 |
| 13 | oxidative phosphorylation (GO:0006119) | 3.99688460 |
| 14 | protein complex biogenesis (GO:0070271) | 3.99140974 |
| 15 | electron transport chain (GO:0022900) | 3.95328425 |
| 16 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.87039197 |
| 17 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 3.83444356 |
| 18 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.82500258 |
| 19 | NADH dehydrogenase complex assembly (GO:0010257) | 3.82500258 |
| 20 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.82500258 |
| 21 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.81564094 |
| 22 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.77991921 |
| 23 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.73593137 |
| 24 | negative regulation of ligase activity (GO:0051352) | 3.73593137 |
| 25 | establishment of integrated proviral latency (GO:0075713) | 3.73191377 |
| 26 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.67162851 |
| 27 | chaperone-mediated protein transport (GO:0072321) | 3.65448081 |
| 28 | protein deneddylation (GO:0000338) | 3.64044969 |
| 29 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.63935949 |
| 30 | cullin deneddylation (GO:0010388) | 3.58572938 |
| 31 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.58410538 |
| 32 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.55358620 |
| 33 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.55358620 |
| 34 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.55358620 |
| 35 | purine deoxyribonucleotide catabolic process (GO:0009155) | 3.55287220 |
| 36 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 3.54578443 |
| 37 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 3.54578443 |
| 38 | deoxyribonucleotide catabolic process (GO:0009264) | 3.52628575 |
| 39 | GTP biosynthetic process (GO:0006183) | 3.52594480 |
| 40 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.48610739 |
| 41 | deoxyribonucleoside triphosphate metabolic process (GO:0009200) | 3.48243324 |
| 42 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 3.44793407 |
| 43 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 3.44793407 |
| 44 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 3.41813758 |
| 45 | protein targeting to mitochondrion (GO:0006626) | 3.40883218 |
| 46 | deoxyribose phosphate catabolic process (GO:0046386) | 3.40092629 |
| 47 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 3.38987758 |
| 48 | base-excision repair, AP site formation (GO:0006285) | 3.38462677 |
| 49 | pyrimidine deoxyribonucleotide metabolic process (GO:0009219) | 3.37945966 |
| 50 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 3.36224909 |
| 51 | positive regulation of prostaglandin secretion (GO:0032308) | 3.33177195 |
| 52 | ubiquinone biosynthetic process (GO:0006744) | 3.33081806 |
| 53 | guanosine-containing compound biosynthetic process (GO:1901070) | 3.31720546 |
| 54 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.29594727 |
| 55 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.29594727 |
| 56 | negative regulation of B cell apoptotic process (GO:0002903) | 3.26756525 |
| 57 | establishment of protein localization to mitochondrion (GO:0072655) | 3.23306725 |
| 58 | purine nucleotide salvage (GO:0032261) | 3.23301640 |
| 59 | peptidyl-arginine omega-N-methylation (GO:0035247) | 3.21994776 |
| 60 | respiratory chain complex IV assembly (GO:0008535) | 3.21547722 |
| 61 | antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590) | 3.17813411 |
| 62 | pyrimidine nucleotide catabolic process (GO:0006244) | 3.16188468 |
| 63 | cytochrome complex assembly (GO:0017004) | 3.14521799 |
| 64 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 3.12978042 |
| 65 | UTP biosynthetic process (GO:0006228) | 3.11020282 |
| 66 | protein localization to mitochondrion (GO:0070585) | 3.10268103 |
| 67 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.10064858 |
| 68 | pyrimidine nucleoside triphosphate metabolic process (GO:0009147) | 3.08078969 |
| 69 | ubiquinone metabolic process (GO:0006743) | 3.05908915 |
| 70 | 2-deoxyribonucleotide metabolic process (GO:0009394) | 3.04962072 |
| 71 | positive regulation of ligase activity (GO:0051351) | 3.02926403 |
| 72 | mannosylation (GO:0097502) | 3.01515764 |
| 73 | UTP metabolic process (GO:0046051) | 3.01319289 |
| 74 | L-methionine biosynthetic process from methylthioadenosine (GO:0019509) | 3.00761133 |
| 75 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.00125958 |
| 76 | spliceosomal snRNP assembly (GO:0000387) | 2.98334507 |
| 77 | tricarboxylic acid cycle (GO:0006099) | 2.97504204 |
| 78 | NADH metabolic process (GO:0006734) | 2.94763222 |
| 79 | deoxyribose phosphate metabolic process (GO:0019692) | 2.91629684 |
| 80 | pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148) | 2.91505777 |
| 81 | protein neddylation (GO:0045116) | 2.90519350 |
| 82 | deoxyribose phosphate biosynthetic process (GO:0046385) | 2.90283017 |
| 83 | 2-deoxyribonucleotide biosynthetic process (GO:0009265) | 2.90283017 |
| 84 | pseudouridine synthesis (GO:0001522) | 2.88697062 |
| 85 | CTP biosynthetic process (GO:0006241) | 2.87437065 |
| 86 | CTP metabolic process (GO:0046036) | 2.87437065 |
| 87 | protein maturation by protein folding (GO:0022417) | 2.87426147 |
| 88 | purine deoxyribonucleoside triphosphate metabolic process (GO:0009215) | 2.87145676 |
| 89 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 2.84399167 |
| 90 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 2.83505224 |
| 91 | DNA damage response, signal transduction by p53 class mediator (GO:0030330) | 2.83235127 |
| 92 | mitochondrial calcium ion transport (GO:0006851) | 2.82688429 |
| 93 | peptidyl-histidine modification (GO:0018202) | 2.82019010 |
| 94 | purine deoxyribonucleotide metabolic process (GO:0009151) | 2.78162659 |
| 95 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 2.78088389 |
| 96 | termination of RNA polymerase III transcription (GO:0006386) | 2.78088389 |
| 97 | quinone biosynthetic process (GO:1901663) | 2.77544997 |
| 98 | aerobic respiration (GO:0009060) | 2.76402758 |
| 99 | telomere maintenance via semi-conservative replication (GO:0032201) | 2.75429132 |
| 100 | regulation of ubiquitin-protein transferase activity (GO:0051438) | 2.74744105 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.23965028 |
| 2 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 3.85259286 |
| 3 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 3.80125740 |
| 4 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.64354451 |
| 5 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 3.51750273 |
| 6 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 3.32631626 |
| 7 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 3.26584520 |
| 8 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.24632325 |
| 9 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 3.10063906 |
| 10 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.96736430 |
| 11 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 2.95445958 |
| 12 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 2.85420703 |
| 13 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.80457016 |
| 14 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.78798195 |
| 15 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.70740176 |
| 16 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.63413013 |
| 17 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 2.60990135 |
| 18 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.59512909 |
| 19 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 2.50554100 |
| 20 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 2.49906008 |
| 21 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 2.45536044 |
| 22 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 2.43783256 |
| 23 | E2F7_22180533_ChIP-Seq_HELA_Human | 2.38105155 |
| 24 | GABP_19822575_ChIP-Seq_HepG2_Human | 2.27618485 |
| 25 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.27054216 |
| 26 | DCP1A_22483619_ChIP-Seq_HELA_Human | 2.26450600 |
| 27 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 2.25278462 |
| 28 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 2.18582111 |
| 29 | XRN2_22483619_ChIP-Seq_HELA_Human | 2.17247146 |
| 30 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 2.11629539 |
| 31 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 2.02976021 |
| 32 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 2.00979583 |
| 33 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.99417455 |
| 34 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.96320207 |
| 35 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.91055961 |
| 36 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.84448492 |
| 37 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.79444554 |
| 38 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.78792989 |
| 39 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.78739290 |
| 40 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.77161379 |
| 41 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.76584753 |
| 42 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.74363815 |
| 43 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.74115580 |
| 44 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.73490405 |
| 45 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.72727207 |
| 46 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 1.71484397 |
| 47 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.68490226 |
| 48 | CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 1.67751920 |
| 49 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 1.65452091 |
| 50 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.65182023 |
| 51 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 1.58848020 |
| 52 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.46226464 |
| 53 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 1.43519850 |
| 54 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.41109958 |
| 55 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.40090281 |
| 56 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 1.37654934 |
| 57 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.33088730 |
| 58 | ZFX_18555785_ChIP-Seq_MESCs_Mouse | 1.32881822 |
| 59 | KDM5A_27292631_Chip-Seq_BREAST_Human | 1.29954033 |
| 60 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.29303727 |
| 61 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.27986897 |
| 62 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.26278587 |
| 63 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.21771326 |
| 64 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.20081004 |
| 65 | ZNF263_19887448_ChIP-Seq_K562_Human | 1.18279852 |
| 66 | DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 1.16078097 |
| 67 | CNOT3_19339689_ChIP-ChIP_MESCs_Mouse | 1.14672281 |
| 68 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.13273579 |
| 69 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.12927652 |
| 70 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.12325867 |
| 71 | ESRRB_18555785_ChIP-Seq_MESCs_Mouse | 1.12225106 |
| 72 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.11466529 |
| 73 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.11439270 |
| 74 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.11280710 |
| 75 | BCL6_27268052_Chip-Seq_Bcells_Human | 1.10756857 |
| 76 | E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 1.09803889 |
| 77 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 1.09158797 |
| 78 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.08378113 |
| 79 | SPI1_23547873_ChIP-Seq_NB4_Human | 1.06634794 |
| 80 | CTCF_18555785_ChIP-Seq_MESCs_Mouse | 1.06415251 |
| 81 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.05938803 |
| 82 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.04451741 |
| 83 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.03929804 |
| 84 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 1.03068641 |
| 85 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 1.02998971 |
| 86 | FOXP1_21924763_ChIP-Seq_HESCs_Human | 0.98021037 |
| 87 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 0.97165646 |
| 88 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 0.96524321 |
| 89 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.96320692 |
| 90 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 0.95786719 |
| 91 | GFI1B_20887958_ChIP-Seq_HPC-7_Mouse | 0.95533548 |
| 92 | YY1_22570637_ChIP-Seq_MALME-3M_Human | 0.94380076 |
| 93 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 0.93657231 |
| 94 | VDR_21846776_ChIP-Seq_THP-1_Human | 0.91822016 |
| 95 | SIN3A_21632747_ChIP-Seq_MESCs_Mouse | 0.91518636 |
| 96 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 0.90861240 |
| 97 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 0.88959604 |
| 98 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 0.87552324 |
| 99 | CTCF_26484167_Chip-Seq_Bcells_Mouse | 0.86561221 |
| 100 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 0.86298211 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0006036_abnormal_mitochondrial_physio | 3.19200984 |
| 2 | MP0008058_abnormal_DNA_repair | 3.17430080 |
| 3 | MP0003806_abnormal_nucleotide_metabolis | 3.14767898 |
| 4 | MP0005645_abnormal_hypothalamus_physiol | 2.98304697 |
| 5 | MP0005671_abnormal_response_to | 2.90941854 |
| 6 | MP0010094_abnormal_chromosome_stability | 2.70202622 |
| 7 | MP0001835_abnormal_antigen_presentation | 2.57798792 |
| 8 | MP0003693_abnormal_embryo_hatching | 2.47699990 |
| 9 | MP0001529_abnormal_vocalization | 2.28686350 |
| 10 | MP0006035_abnormal_mitochondrial_morpho | 2.19422557 |
| 11 | MP0004145_abnormal_muscle_electrophysio | 2.17135923 |
| 12 | MP0009785_altered_susceptibility_to | 2.16108817 |
| 13 | MP0002102_abnormal_ear_morphology | 2.15559603 |
| 14 | MP0004147_increased_porphyrin_level | 2.08647996 |
| 15 | MP0002148_abnormal_hypersensitivity_rea | 2.06232089 |
| 16 | MP0003786_premature_aging | 2.05484470 |
| 17 | MP0009333_abnormal_splenocyte_physiolog | 2.01792064 |
| 18 | MP0003111_abnormal_nucleus_morphology | 1.97523127 |
| 19 | MP0003763_abnormal_thymus_physiology | 1.89505624 |
| 20 | MP0008007_abnormal_cellular_replicative | 1.86152555 |
| 21 | MP0003186_abnormal_redox_activity | 1.82844494 |
| 22 | MP0005075_abnormal_melanosome_morpholog | 1.78065731 |
| 23 | MP0000685_abnormal_immune_system | 1.77006320 |
| 24 | MP0004957_abnormal_blastocyst_morpholog | 1.66799526 |
| 25 | MP0005000_abnormal_immune_tolerance | 1.65448112 |
| 26 | MP0009764_decreased_sensitivity_to | 1.63391539 |
| 27 | MP0001800_abnormal_humoral_immune | 1.63215415 |
| 28 | MP0008932_abnormal_embryonic_tissue | 1.59984099 |
| 29 | MP0002822_catalepsy | 1.59955475 |
| 30 | MP0003646_muscle_fatigue | 1.59429064 |
| 31 | MP0009697_abnormal_copulation | 1.59159921 |
| 32 | MP0005084_abnormal_gallbladder_morpholo | 1.53807250 |
| 33 | MP0001727_abnormal_embryo_implantation | 1.50455569 |
| 34 | MP0003077_abnormal_cell_cycle | 1.50357207 |
| 35 | MP0001873_stomach_inflammation | 1.46003294 |
| 36 | MP0005330_cardiomyopathy | 1.45741880 |
| 37 | MP0002452_abnormal_antigen_presenting | 1.45518982 |
| 38 | MP0006072_abnormal_retinal_apoptosis | 1.44774946 |
| 39 | MP0009278_abnormal_bone_marrow | 1.43716604 |
| 40 | MP0000465_gastrointestinal_hemorrhage | 1.43167702 |
| 41 | MP0002723_abnormal_immune_serum | 1.43150511 |
| 42 | MP0001819_abnormal_immune_cell | 1.42310514 |
| 43 | MP0005025_abnormal_response_to | 1.41111057 |
| 44 | MP0002420_abnormal_adaptive_immunity | 1.40521258 |
| 45 | MP0000751_myopathy | 1.39561731 |
| 46 | MP0002837_dystrophic_cardiac_calcinosis | 1.38988983 |
| 47 | MP0002653_abnormal_ependyma_morphology | 1.38910333 |
| 48 | MP0005387_immune_system_phenotype | 1.36920510 |
| 49 | MP0001790_abnormal_immune_system | 1.36920510 |
| 50 | MP0003866_abnormal_defecation | 1.34692604 |
| 51 | MP0000749_muscle_degeneration | 1.33768291 |
| 52 | MP0003718_maternal_effect | 1.32049080 |
| 53 | MP0002398_abnormal_bone_marrow | 1.31465473 |
| 54 | MP0000689_abnormal_spleen_morphology | 1.30864947 |
| 55 | MP0001764_abnormal_homeostasis | 1.30473334 |
| 56 | MP0000372_irregular_coat_pigmentation | 1.24001735 |
| 57 | MP0003221_abnormal_cardiomyocyte_apopto | 1.22563138 |
| 58 | MP0002019_abnormal_tumor_incidence | 1.22377838 |
| 59 | MP0002722_abnormal_immune_system | 1.21620489 |
| 60 | MP0003436_decreased_susceptibility_to | 1.21308421 |
| 61 | MP0000750_abnormal_muscle_regeneration | 1.20709433 |
| 62 | MP0008789_abnormal_olfactory_epithelium | 1.19922093 |
| 63 | MP0000716_abnormal_immune_system | 1.19838938 |
| 64 | MP0003315_abnormal_perineum_morphology | 1.18134084 |
| 65 | MP0002163_abnormal_gland_morphology | 1.17862593 |
| 66 | MP0005266_abnormal_metabolism | 1.16441647 |
| 67 | MP0005451_abnormal_body_composition | 1.15071939 |
| 68 | MP0002277_abnormal_respiratory_mucosa | 1.14313984 |
| 69 | MP0002429_abnormal_blood_cell | 1.12033208 |
| 70 | MP0001905_abnormal_dopamine_level | 1.11201470 |
| 71 | MP0008872_abnormal_physiological_respon | 1.06219031 |
| 72 | MP0001845_abnormal_inflammatory_respons | 1.04915581 |
| 73 | MP0006276_abnormal_autonomic_nervous | 1.03645899 |
| 74 | MP0001545_abnormal_hematopoietic_system | 1.02682644 |
| 75 | MP0005397_hematopoietic_system_phenotyp | 1.02682644 |
| 76 | MP0000490_abnormal_crypts_of | 1.01225563 |
| 77 | MP0004510_myositis | 1.00506124 |
| 78 | MP0000313_abnormal_cell_death | 1.00146705 |
| 79 | MP0009763_increased_sensitivity_to | 0.99762512 |
| 80 | MP0008469_abnormal_protein_level | 0.98307720 |
| 81 | MP0000358_abnormal_cell_content/ | 0.97762058 |
| 82 | MP0005165_increased_susceptibility_to | 0.92143647 |
| 83 | MP0002106_abnormal_muscle_physiology | 0.91012577 |
| 84 | MP0002332_abnormal_exercise_endurance | 0.90809867 |
| 85 | MP0003137_abnormal_impulse_conducting | 0.89557947 |
| 86 | MP0010155_abnormal_intestine_physiology | 0.89345074 |
| 87 | MP0008995_early_reproductive_senescence | 0.89038566 |
| 88 | MP0000747_muscle_weakness | 0.88717618 |
| 89 | MP0005367_renal/urinary_system_phenotyp | 0.87681892 |
| 90 | MP0000516_abnormal_urinary_system | 0.87681892 |
| 91 | MP0000703_abnormal_thymus_morphology | 0.84846425 |
| 92 | MP0002166_altered_tumor_susceptibility | 0.83643694 |
| 93 | MP0002006_tumorigenesis | 0.82940957 |
| 94 | MP0005584_abnormal_enzyme/coenzyme_acti | 0.82928749 |
| 95 | MP0005670_abnormal_white_adipose | 0.81258658 |
| 96 | MP0005319_abnormal_enzyme/_coenzyme | 0.79936847 |
| 97 | MP0002234_abnormal_pharynx_morphology | 0.79434869 |
| 98 | MP0005332_abnormal_amino_acid | 0.78440475 |
| 99 | MP0008875_abnormal_xenobiotic_pharmacok | 0.78417370 |
| 100 | MP0002419_abnormal_innate_immunity | 0.74977055 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Hepatocellular necrosis (HP:0001404) | 5.40428322 |
| 2 | Abnormal mitochondria in muscle tissue (HP:0008316) | 5.23455380 |
| 3 | Mitochondrial inheritance (HP:0001427) | 5.09027828 |
| 4 | Hepatic necrosis (HP:0002605) | 4.97702037 |
| 5 | Acute necrotizing encephalopathy (HP:0006965) | 4.97433259 |
| 6 | Increased intramyocellular lipid droplets (HP:0012240) | 4.72867279 |
| 7 | Increased CSF lactate (HP:0002490) | 4.58999688 |
| 8 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 4.47993513 |
| 9 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 4.47993513 |
| 10 | Acute encephalopathy (HP:0006846) | 4.42021757 |
| 11 | Increased muscle lipid content (HP:0009058) | 4.36304937 |
| 12 | Progressive macrocephaly (HP:0004481) | 3.85253999 |
| 13 | Lipid accumulation in hepatocytes (HP:0006561) | 3.82513440 |
| 14 | Increased hepatocellular lipid droplets (HP:0006565) | 3.80487742 |
| 15 | Lactic acidosis (HP:0003128) | 3.64859160 |
| 16 | Increased serum lactate (HP:0002151) | 3.58845549 |
| 17 | Cerebral edema (HP:0002181) | 3.48800228 |
| 18 | Exercise intolerance (HP:0003546) | 3.31011076 |
| 19 | Aplastic anemia (HP:0001915) | 3.26777894 |
| 20 | Renal Fanconi syndrome (HP:0001994) | 3.13905281 |
| 21 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 3.12325036 |
| 22 | Increased serum pyruvate (HP:0003542) | 3.00524597 |
| 23 | Ragged-red muscle fibers (HP:0003200) | 2.98739696 |
| 24 | IgM deficiency (HP:0002850) | 2.97670573 |
| 25 | Respiratory failure (HP:0002878) | 2.97416879 |
| 26 | Abnormality of glycolysis (HP:0004366) | 2.96296634 |
| 27 | Dicarboxylic aciduria (HP:0003215) | 2.89907096 |
| 28 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 2.89907096 |
| 29 | Type I transferrin isoform profile (HP:0003642) | 2.88101923 |
| 30 | Microvesicular hepatic steatosis (HP:0001414) | 2.85767764 |
| 31 | Degeneration of anterior horn cells (HP:0002398) | 2.83510217 |
| 32 | Abnormality of the anterior horn cell (HP:0006802) | 2.83510217 |
| 33 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.75750047 |
| 34 | Rhabdomyolysis (HP:0003201) | 2.71715622 |
| 35 | Emotional lability (HP:0000712) | 2.70682272 |
| 36 | 3-Methylglutaconic aciduria (HP:0003535) | 2.67056200 |
| 37 | IgG deficiency (HP:0004315) | 2.59015051 |
| 38 | Exertional dyspnea (HP:0002875) | 2.56909472 |
| 39 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 2.56639216 |
| 40 | Abnormal protein N-linked glycosylation (HP:0012347) | 2.56639216 |
| 41 | Abnormal protein glycosylation (HP:0012346) | 2.56639216 |
| 42 | Abnormal glycosylation (HP:0012345) | 2.56639216 |
| 43 | B lymphocytopenia (HP:0010976) | 2.52883197 |
| 44 | Myoglobinuria (HP:0002913) | 2.50483122 |
| 45 | Abnormality of alanine metabolism (HP:0010916) | 2.49013502 |
| 46 | Hyperalaninemia (HP:0003348) | 2.49013502 |
| 47 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.49013502 |
| 48 | Methylmalonic aciduria (HP:0012120) | 2.47556727 |
| 49 | Optic disc pallor (HP:0000543) | 2.46454264 |
| 50 | Lethargy (HP:0001254) | 2.35935025 |
| 51 | Abnormality of B cell number (HP:0010975) | 2.34768990 |
| 52 | CNS demyelination (HP:0007305) | 2.34204514 |
| 53 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.31241006 |
| 54 | Pancytopenia (HP:0001876) | 2.29671412 |
| 55 | Nemaline bodies (HP:0003798) | 2.27921232 |
| 56 | Progressive microcephaly (HP:0000253) | 2.27866665 |
| 57 | Atrophy/Degeneration involving motor neurons (HP:0007373) | 2.27038113 |
| 58 | Cerebral palsy (HP:0100021) | 2.23806454 |
| 59 | Leukodystrophy (HP:0002415) | 2.18646481 |
| 60 | Generalized aminoaciduria (HP:0002909) | 2.15967356 |
| 61 | Palpitations (HP:0001962) | 2.12427026 |
| 62 | Muscle fiber atrophy (HP:0100295) | 2.10901677 |
| 63 | Hyperglycinemia (HP:0002154) | 2.08944940 |
| 64 | Muscle fiber cytoplasmatic inclusion bodies (HP:0100303) | 2.06979686 |
| 65 | Muscle fiber inclusion bodies (HP:0100299) | 2.06126011 |
| 66 | Methylmalonic acidemia (HP:0002912) | 2.05052332 |
| 67 | Respiratory difficulties (HP:0002880) | 2.04882665 |
| 68 | Severe combined immunodeficiency (HP:0004430) | 2.02760879 |
| 69 | Gliosis (HP:0002171) | 2.00147757 |
| 70 | Microretrognathia (HP:0000308) | 1.99474473 |
| 71 | Increased IgM level (HP:0003496) | 1.99459700 |
| 72 | Opisthotonus (HP:0002179) | 1.91175351 |
| 73 | Agammaglobulinemia (HP:0004432) | 1.90891908 |
| 74 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 1.89738078 |
| 75 | Reduced antithrombin III activity (HP:0001976) | 1.89564996 |
| 76 | Oral leukoplakia (HP:0002745) | 1.88977427 |
| 77 | Type 2 muscle fiber atrophy (HP:0003554) | 1.87782443 |
| 78 | Abnormality of serine family amino acid metabolism (HP:0010894) | 1.87542430 |
| 79 | Abnormality of glycine metabolism (HP:0010895) | 1.87542430 |
| 80 | Hyperglycinuria (HP:0003108) | 1.83827051 |
| 81 | Rimmed vacuoles (HP:0003805) | 1.82033988 |
| 82 | Abnormality of serum amino acid levels (HP:0003112) | 1.80770359 |
| 83 | Aplasia/hypoplasia of the uterus (HP:0008684) | 1.79203502 |
| 84 | Cleft eyelid (HP:0000625) | 1.77846747 |
| 85 | Hepatosplenomegaly (HP:0001433) | 1.76626363 |
| 86 | Progressive muscle weakness (HP:0003323) | 1.76236862 |
| 87 | Exercise-induced muscle cramps (HP:0003710) | 1.75207985 |
| 88 | Abnormality of fatty-acid metabolism (HP:0004359) | 1.75082387 |
| 89 | Cerebral hypomyelination (HP:0006808) | 1.70618923 |
| 90 | Nausea (HP:0002018) | 1.68140984 |
| 91 | Retinal dysplasia (HP:0007973) | 1.67821961 |
| 92 | Mediastinal lymphadenopathy (HP:0100721) | 1.67248067 |
| 93 | Combined immunodeficiency (HP:0005387) | 1.66915179 |
| 94 | Ketoacidosis (HP:0001993) | 1.66581303 |
| 95 | Abnormality of the prostate (HP:0008775) | 1.66349237 |
| 96 | Delayed CNS myelination (HP:0002188) | 1.65493742 |
| 97 | Petechiae (HP:0000967) | 1.64698889 |
| 98 | Hypertensive crisis (HP:0100735) | 1.64272736 |
| 99 | Testicular atrophy (HP:0000029) | 1.64206940 |
| 100 | Abnormality of T cell physiology (HP:0011840) | 1.63927374 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | VRK2 | 4.52058361 |
| 2 | BCKDK | 4.38390926 |
| 3 | TESK2 | 3.62702064 |
| 4 | KDR | 3.33788838 |
| 5 | BUB1 | 2.85940356 |
| 6 | NME2 | 2.57639320 |
| 7 | ZAK | 2.53863938 |
| 8 | TESK1 | 2.50428030 |
| 9 | VRK1 | 2.45673092 |
| 10 | SRPK1 | 2.20869012 |
| 11 | SCYL2 | 2.16346338 |
| 12 | MAP4K2 | 2.12108628 |
| 13 | PIM2 | 2.06519536 |
| 14 | LIMK1 | 1.99471080 |
| 15 | NEK1 | 1.93988308 |
| 16 | MAP3K11 | 1.89879934 |
| 17 | MAP2K7 | 1.81187943 |
| 18 | CSNK1G3 | 1.76821898 |
| 19 | ARAF | 1.75580485 |
| 20 | TLK1 | 1.66282429 |
| 21 | CDC7 | 1.63379298 |
| 22 | MAP4K1 | 1.58601970 |
| 23 | STK16 | 1.47867372 |
| 24 | NUAK1 | 1.47733504 |
| 25 | CSNK1A1L | 1.35862776 |
| 26 | CSNK1G1 | 1.35262583 |
| 27 | TXK | 1.31151947 |
| 28 | CSNK1G2 | 1.30207055 |
| 29 | DAPK1 | 1.29557370 |
| 30 | RPS6KA5 | 1.21467298 |
| 31 | OBSCN | 1.16217822 |
| 32 | CDK19 | 1.16114502 |
| 33 | RPS6KA4 | 1.15011271 |
| 34 | TBK1 | 1.12687712 |
| 35 | AURKA | 1.09499918 |
| 36 | TAOK3 | 1.05340953 |
| 37 | MAPKAPK3 | 1.02978132 |
| 38 | TRIM28 | 0.98695824 |
| 39 | DAPK3 | 0.98656281 |
| 40 | PLK4 | 0.98486745 |
| 41 | CCNB1 | 0.97347682 |
| 42 | BCR | 0.96930414 |
| 43 | NME1 | 0.96074396 |
| 44 | KIT | 0.90677968 |
| 45 | MAP3K12 | 0.89452130 |
| 46 | MST4 | 0.89247403 |
| 47 | IKBKB | 0.87900994 |
| 48 | TAOK2 | 0.87626096 |
| 49 | ABL2 | 0.86402008 |
| 50 | DYRK2 | 0.84756598 |
| 51 | CDK8 | 0.83927965 |
| 52 | IKBKE | 0.83055592 |
| 53 | EIF2AK3 | 0.81305246 |
| 54 | AURKB | 0.81072356 |
| 55 | TSSK6 | 0.79512844 |
| 56 | ATR | 0.79095640 |
| 57 | ADRBK2 | 0.74809090 |
| 58 | WNK3 | 0.71904401 |
| 59 | CHEK2 | 0.68453863 |
| 60 | PLK1 | 0.65214596 |
| 61 | ERBB3 | 0.64401905 |
| 62 | IRAK3 | 0.57186529 |
| 63 | SYK | 0.56921068 |
| 64 | PDK2 | 0.55269270 |
| 65 | MAP3K4 | 0.55259392 |
| 66 | PHKG1 | 0.54845921 |
| 67 | PHKG2 | 0.54845921 |
| 68 | GRK7 | 0.53651080 |
| 69 | PBK | 0.52563097 |
| 70 | DYRK3 | 0.50283828 |
| 71 | MUSK | 0.50077313 |
| 72 | MYLK | 0.50028669 |
| 73 | LMTK2 | 0.49223456 |
| 74 | CSNK2A1 | 0.48873832 |
| 75 | PRKCI | 0.48582242 |
| 76 | TAF1 | 0.46524082 |
| 77 | CDK7 | 0.42435838 |
| 78 | CDK14 | 0.41911586 |
| 79 | CSNK2A2 | 0.41535592 |
| 80 | MATK | 0.41362536 |
| 81 | GRK6 | 0.40997037 |
| 82 | PAK1 | 0.40978194 |
| 83 | ILK | 0.40869306 |
| 84 | EIF2AK2 | 0.40604152 |
| 85 | DYRK1B | 0.38734639 |
| 86 | PINK1 | 0.35933852 |
| 87 | LYN | 0.35722633 |
| 88 | FLT3 | 0.34712136 |
| 89 | PLK3 | 0.34337454 |
| 90 | MAPK11 | 0.33736642 |
| 91 | BRAF | 0.33394726 |
| 92 | GRK1 | 0.33166848 |
| 93 | CSNK1A1 | 0.32298796 |
| 94 | PASK | 0.32031899 |
| 95 | PIM1 | 0.31666223 |
| 96 | MAP3K5 | 0.31657229 |
| 97 | CSF1R | 0.31601158 |
| 98 | CDK11A | 0.31216287 |
| 99 | MAP3K14 | 0.30727736 |
| 100 | IRAK4 | 0.28682542 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 4.39588455 |
| 2 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.54536789 |
| 3 | Parkinsons disease_Homo sapiens_hsa05012 | 3.25843707 |
| 4 | DNA replication_Homo sapiens_hsa03030 | 2.69364714 |
| 5 | Ribosome_Homo sapiens_hsa03010 | 2.37021635 |
| 6 | Base excision repair_Homo sapiens_hsa03410 | 2.32709649 |
| 7 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 2.30263227 |
| 8 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 2.21399326 |
| 9 | Primary immunodeficiency_Homo sapiens_hsa05340 | 2.18981688 |
| 10 | RNA polymerase_Homo sapiens_hsa03020 | 2.16282915 |
| 11 | Mismatch repair_Homo sapiens_hsa03430 | 2.16157383 |
| 12 | Huntingtons disease_Homo sapiens_hsa05016 | 2.13020287 |
| 13 | Asthma_Homo sapiens_hsa05310 | 2.05131691 |
| 14 | Alzheimers disease_Homo sapiens_hsa05010 | 1.97381970 |
| 15 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.81051270 |
| 16 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.78400937 |
| 17 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.76147669 |
| 18 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.73447864 |
| 19 | Sulfur relay system_Homo sapiens_hsa04122 | 1.73172443 |
| 20 | Spliceosome_Homo sapiens_hsa03040 | 1.71843119 |
| 21 | Allograft rejection_Homo sapiens_hsa05330 | 1.71256986 |
| 22 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 1.69854349 |
| 23 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.67516154 |
| 24 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.64565457 |
| 25 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.56353450 |
| 26 | Homologous recombination_Homo sapiens_hsa03440 | 1.53106732 |
| 27 | Protein export_Homo sapiens_hsa03060 | 1.51494715 |
| 28 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.50126142 |
| 29 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.48032998 |
| 30 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.43870383 |
| 31 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.43039780 |
| 32 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.40361000 |
| 33 | Carbon metabolism_Homo sapiens_hsa01200 | 1.40213662 |
| 34 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 1.39357045 |
| 35 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 1.28550254 |
| 36 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.28271340 |
| 37 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.26084323 |
| 38 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.25496206 |
| 39 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.23983767 |
| 40 | Viral myocarditis_Homo sapiens_hsa05416 | 1.20084199 |
| 41 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.19242167 |
| 42 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.16710011 |
| 43 | Purine metabolism_Homo sapiens_hsa00230 | 1.14499704 |
| 44 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.11143614 |
| 45 | RNA degradation_Homo sapiens_hsa03018 | 1.07187568 |
| 46 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.03208737 |
| 47 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.02492527 |
| 48 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.01342813 |
| 49 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 1.01198125 |
| 50 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.00800332 |
| 51 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.99719157 |
| 52 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.96909393 |
| 53 | RNA transport_Homo sapiens_hsa03013 | 0.95945911 |
| 54 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.94944371 |
| 55 | Peroxisome_Homo sapiens_hsa04146 | 0.92101072 |
| 56 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.90391846 |
| 57 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.88368203 |
| 58 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.84475227 |
| 59 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.83173588 |
| 60 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.82349384 |
| 61 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.76946924 |
| 62 | Basal transcription factors_Homo sapiens_hsa03022 | 0.76588328 |
| 63 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.74931059 |
| 64 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.74851105 |
| 65 | Metabolic pathways_Homo sapiens_hsa01100 | 0.72432682 |
| 66 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.69226955 |
| 67 | Alcoholism_Homo sapiens_hsa05034 | 0.67525517 |
| 68 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.64650155 |
| 69 | Galactose metabolism_Homo sapiens_hsa00052 | 0.63237286 |
| 70 | Shigellosis_Homo sapiens_hsa05131 | 0.61161998 |
| 71 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.60133451 |
| 72 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.55383693 |
| 73 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.54328493 |
| 74 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.51768168 |
| 75 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.51127079 |
| 76 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.50561065 |
| 77 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.50221093 |
| 78 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.48067852 |
| 79 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.46741502 |
| 80 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.46602000 |
| 81 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.46083454 |
| 82 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.44944866 |
| 83 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.43376241 |
| 84 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.42774083 |
| 85 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.40604381 |
| 86 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.40296224 |
| 87 | Cell cycle_Homo sapiens_hsa04110 | 0.39277782 |
| 88 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.37698882 |
| 89 | Leishmaniasis_Homo sapiens_hsa05140 | 0.37411270 |
| 90 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.35708840 |
| 91 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.34401366 |
| 92 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.32784123 |
| 93 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.31875837 |
| 94 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.30735730 |
| 95 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.30577730 |
| 96 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.28600045 |
| 97 | Salmonella infection_Homo sapiens_hsa05132 | 0.27663165 |
| 98 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.22091369 |
| 99 | Legionellosis_Homo sapiens_hsa05134 | 0.21815354 |
| 100 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.20634160 |

