USMG5

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1energy coupled proton transport, down electrochemical gradient (GO:0015985)9.80739762
2ATP synthesis coupled proton transport (GO:0015986)9.80739762
3mitochondrial electron transport, NADH to ubiquinone (GO:0006120)8.94528795
4respiratory electron transport chain (GO:0022904)8.12042374
5electron transport chain (GO:0022900)7.91618597
6establishment of protein localization to mitochondrial membrane (GO:0090151)5.76444071
7chaperone-mediated protein transport (GO:0072321)5.71050227
8viral transcription (GO:0019083)5.33091270
9ATP biosynthetic process (GO:0006754)5.26117914
10translational termination (GO:0006415)5.21713576
11hydrogen ion transmembrane transport (GO:1902600)5.16434716
12ribosomal small subunit assembly (GO:0000028)5.12465332
13SRP-dependent cotranslational protein targeting to membrane (GO:0006614)4.99944835
14cotranslational protein targeting to membrane (GO:0006613)4.98613536
15protein targeting to ER (GO:0045047)4.91536079
16purine ribonucleoside triphosphate biosynthetic process (GO:0009206)4.89095233
17inner mitochondrial membrane organization (GO:0007007)4.81857852
18purine nucleoside triphosphate biosynthetic process (GO:0009145)4.78496267
19establishment of protein localization to endoplasmic reticulum (GO:0072599)4.74030723
20protein complex biogenesis (GO:0070271)4.68636759
21protein localization to endoplasmic reticulum (GO:0070972)4.65815552
22protein neddylation (GO:0045116)4.65725318
23proton transport (GO:0015992)4.53240737
24mitochondrial respiratory chain complex I biogenesis (GO:0097031)4.46009146
25mitochondrial respiratory chain complex I assembly (GO:0032981)4.46009146
26NADH dehydrogenase complex assembly (GO:0010257)4.46009146
27hydrogen transport (GO:0006818)4.45774587
28translational elongation (GO:0006414)4.33538051
29oxidative phosphorylation (GO:0006119)4.25275779
30mitochondrial respiratory chain complex assembly (GO:0033108)4.23314274
31ribonucleoside triphosphate biosynthetic process (GO:0009201)4.21872089
32ribosomal large subunit biogenesis (GO:0042273)4.21372296
33termination of RNA polymerase III transcription (GO:0006386)4.17515248
34transcription elongation from RNA polymerase III promoter (GO:0006385)4.17515248
35energy coupled proton transmembrane transport, against electrochemical gradient (GO:0015988)4.16612528
36ATP hydrolysis coupled proton transport (GO:0015991)4.16612528
37translation (GO:0006412)4.02172002
38cellular protein complex disassembly (GO:0043624)4.02158087
39viral life cycle (GO:0019058)3.93047500
40maturation of SSU-rRNA (GO:0030490)3.92907825
41translational initiation (GO:0006413)3.92814068
42neuron cell-cell adhesion (GO:0007158)3.91189594
43nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.78206988
44nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.77179690
45exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.72951973
46negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.71355561
47dopamine transport (GO:0015872)3.67293314
48regulation of oxidative phosphorylation (GO:0002082)3.66579109
49nucleoside triphosphate biosynthetic process (GO:0009142)3.62656924
50GTP biosynthetic process (GO:0006183)3.59515850
51regulation of protein kinase A signaling (GO:0010738)3.44390259
52sequestering of actin monomers (GO:0042989)3.44385875
53positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.43405896
54regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.38518119
55negative regulation of ligase activity (GO:0051352)3.36101552
56negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.36101552
57cellular component biogenesis (GO:0044085)3.31653030
58protein complex disassembly (GO:0043241)3.29829518
59protein targeting to membrane (GO:0006612)3.28280588
60water-soluble vitamin biosynthetic process (GO:0042364)3.25956684
61regulation of cellular amino acid metabolic process (GO:0006521)3.25833447
62neuronal action potential propagation (GO:0019227)3.25498080
63tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.24384602
64RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.24384602
65macromolecular complex disassembly (GO:0032984)3.24206541
66regulation of mitochondrial translation (GO:0070129)3.24180068
67rRNA modification (GO:0000154)3.21281433
68vocalization behavior (GO:0071625)3.17779674
69mitochondrial transport (GO:0006839)3.16142007
70anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.14870698
71establishment of integrated proviral latency (GO:0075713)3.14569773
72detection of calcium ion (GO:0005513)3.14499675
73CENP-A containing nucleosome assembly (GO:0034080)3.13825151
74chromatin remodeling at centromere (GO:0031055)3.13672298
75negative regulation of ryanodine-sensitive calcium-release channel activity (GO:0060315)3.13330864
76regulation of glutamate secretion (GO:0014048)3.12149102
77aerobic respiration (GO:0009060)3.11858871
78spliceosomal complex assembly (GO:0000245)3.11060577
79establishment of protein localization to mitochondrion (GO:0072655)3.10862161
80substantia nigra development (GO:0021762)3.10774913
81spliceosomal snRNP assembly (GO:0000387)3.10645144
82gamma-aminobutyric acid signaling pathway (GO:0007214)3.10441806
83calcium-mediated signaling using intracellular calcium source (GO:0035584)3.10132421
84synaptic vesicle exocytosis (GO:0016079)3.09787899
85protein targeting to mitochondrion (GO:0006626)3.05836133
86DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:003.05815354
87DNA damage response, detection of DNA damage (GO:0042769)3.04729542
88regulation of dopamine metabolic process (GO:0042053)3.04206787
89regulation of catecholamine metabolic process (GO:0042069)3.04206787
90neuron recognition (GO:0008038)3.01637377
91presynaptic membrane assembly (GO:0097105)3.01031049
92protein localization to mitochondrion (GO:0070585)3.00657880
93generation of precursor metabolites and energy (GO:0006091)3.00212158
94positive regulation of ubiquitin-protein transferase activity (GO:0051443)2.98090732
95regulation of cellular respiration (GO:0043457)2.98029310
96signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)2.97481274
97signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)2.97481274
98signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)2.97481274
99positive regulation of synapse assembly (GO:0051965)2.96678702
100intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)2.96469577
101signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)2.96469577
102positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316)2.95605598
103negative regulation of synaptic transmission, GABAergic (GO:0032229)2.95488227
104transferrin transport (GO:0033572)2.94567596
105nuclear-transcribed mRNA catabolic process (GO:0000956)2.94286681
106pseudouridine synthesis (GO:0001522)2.92280188
107organelle disassembly (GO:1903008)2.90564552
108cullin deneddylation (GO:0010388)2.90255163
109dopamine biosynthetic process (GO:0042416)2.88562921
110UTP biosynthetic process (GO:0006228)2.87665978
111regulation of cell communication by electrical coupling (GO:0010649)2.87556430
112signal transduction involved in DNA damage checkpoint (GO:0072422)2.85583584
113signal transduction involved in DNA integrity checkpoint (GO:0072401)2.85583584
114protein localization to synapse (GO:0035418)2.85526109
115signal transduction involved in cell cycle checkpoint (GO:0072395)2.84517378
116presynaptic membrane organization (GO:0097090)2.84456243
117ribosomal small subunit biogenesis (GO:0042274)2.83481412
118regulation of acyl-CoA biosynthetic process (GO:0050812)2.82903962
119positive regulation of ligase activity (GO:0051351)2.82414829
1207-methylguanosine mRNA capping (GO:0006370)2.82345386
121peptidyl-histidine modification (GO:0018202)2.81661667
122respiratory chain complex IV assembly (GO:0008535)2.81104654
123purine nucleoside monophosphate biosynthetic process (GO:0009127)2.80125077
124purine ribonucleoside monophosphate biosynthetic process (GO:0009168)2.80125077
125regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act2.79093215
126cytochrome complex assembly (GO:0017004)2.78477888
127platelet dense granule organization (GO:0060155)2.77770310
128histone mRNA metabolic process (GO:0008334)2.77303312
129tricarboxylic acid cycle (GO:0006099)2.74978571
130behavioral response to cocaine (GO:0048148)2.74549526
131glutamate receptor signaling pathway (GO:0007215)2.74407460
132protein-cofactor linkage (GO:0018065)2.73151359
133intracellular protein transmembrane import (GO:0044743)2.72847131
134ferric iron transport (GO:0015682)2.71728030
135trivalent inorganic cation transport (GO:0072512)2.71728030
136positive regulation of response to oxidative stress (GO:1902884)2.70004472
137positive regulation of cellular response to oxidative stress (GO:1900409)2.70004472
138regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)2.69208994
139succinate metabolic process (GO:0006105)2.68677691
140regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882)2.65807352
141regulation of coenzyme metabolic process (GO:0051196)2.64922660
142regulation of cofactor metabolic process (GO:0051193)2.64922660
143ionotropic glutamate receptor signaling pathway (GO:0035235)2.64291725
144nucleoside diphosphate phosphorylation (GO:0006165)2.62334641
145response to histamine (GO:0034776)2.61196023
146neuron-neuron synaptic transmission (GO:0007270)2.58825866
147protein localization to cilium (GO:0061512)2.57420812
148synaptic transmission, dopaminergic (GO:0001963)2.54539850
149opioid receptor signaling pathway (GO:0038003)2.51784260
150regulation of glutamate receptor signaling pathway (GO:1900449)2.49668472
151NADH metabolic process (GO:0006734)2.48691695
152positive regulation of potassium ion transmembrane transporter activity (GO:1901018)2.48348085
153guanosine-containing compound biosynthetic process (GO:1901070)2.48271292
154regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion (GO2.48169526
155UTP metabolic process (GO:0046051)2.47672247
156transmission of nerve impulse (GO:0019226)2.46791953
157purine nucleoside biosynthetic process (GO:0042451)2.46108623
158purine ribonucleoside biosynthetic process (GO:0046129)2.46108623
159proteasome assembly (GO:0043248)2.45830007
160positive regulation of inositol phosphate biosynthetic process (GO:0060732)2.44715053
161mitochondrial ATP synthesis coupled proton transport (GO:0042776)10.4958850

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.40486565
2GBX2_23144817_ChIP-Seq_PC3_Human3.24132214
3MYC_18555785_ChIP-Seq_MESCs_Mouse3.15365689
4ELK1_19687146_ChIP-ChIP_HELA_Human3.07267837
5TAF15_26573619_Chip-Seq_HEK293_Human3.03568746
6VDR_22108803_ChIP-Seq_LS180_Human2.92599612
7SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.77450073
8E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.68669684
9JARID2_20064375_ChIP-Seq_MESCs_Mouse2.57022404
10MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.54993825
11SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.50505500
12SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.40211893
13VDR_23849224_ChIP-Seq_CD4+_Human2.39503882
14* ESRRB_18555785_ChIP-Seq_MESCs_Mouse2.28587787
15ZFP57_27257070_Chip-Seq_ESCs_Mouse2.27948652
16EZH2_27304074_Chip-Seq_ESCs_Mouse2.27241926
17BMI1_23680149_ChIP-Seq_NPCS_Mouse2.26595128
18CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.23120647
19CTBP1_25329375_ChIP-Seq_LNCAP_Human2.22860352
20CTBP2_25329375_ChIP-Seq_LNCAP_Human2.16836842
21* KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.16444801
22SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.14158139
23SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.09296228
24FUS_26573619_Chip-Seq_HEK293_Human2.08545892
25JARID2_20075857_ChIP-Seq_MESCs_Mouse2.04622261
26EED_16625203_ChIP-ChIP_MESCs_Mouse2.03057800
27E2F4_17652178_ChIP-ChIP_JURKAT_Human2.01853590
28* MYC_18358816_ChIP-ChIP_MESCs_Mouse2.01410496
29FOXP3_21729870_ChIP-Seq_TREG_Human1.99399299
30* GABP_17652178_ChIP-ChIP_JURKAT_Human1.98796538
31NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.97350214
32SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.96712111
33GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.95742834
34REST_21632747_ChIP-Seq_MESCs_Mouse1.91935621
35FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.91672184
36* MYC_19030024_ChIP-ChIP_MESCs_Mouse1.91143641
37RNF2_18974828_ChIP-Seq_MESCs_Mouse1.87872022
38EZH2_18974828_ChIP-Seq_MESCs_Mouse1.87872022
39TTF2_22483619_ChIP-Seq_HELA_Human1.86404420
40POU3F2_20337985_ChIP-ChIP_501MEL_Human1.85380832
41MYC_18940864_ChIP-ChIP_HL60_Human1.85050952
42TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.80987764
43CBX2_27304074_Chip-Seq_ESCs_Mouse1.80365182
44MYC_19079543_ChIP-ChIP_MESCs_Mouse1.79313431
45P300_19829295_ChIP-Seq_ESCs_Human1.78713217
46MTF2_20144788_ChIP-Seq_MESCs_Mouse1.72897710
47EST1_17652178_ChIP-ChIP_JURKAT_Human1.72321341
48HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.70090390
49E2F1_18555785_ChIP-Seq_MESCs_Mouse1.69530781
50PADI4_21655091_ChIP-ChIP_MCF-7_Human1.68880507
51SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.67406347
52* DCP1A_22483619_ChIP-Seq_HELA_Human1.65965731
53* EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.65167456
54XRN2_22483619_ChIP-Seq_HELA_Human1.61519182
55SUZ12_27294783_Chip-Seq_ESCs_Mouse1.58816672
56EZH2_27294783_Chip-Seq_ESCs_Mouse1.55140785
57ER_23166858_ChIP-Seq_MCF-7_Human1.54981948
58HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.54173007
59ZNF274_21170338_ChIP-Seq_K562_Hela1.54060910
60POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.53891036
61* FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.53565292
62REST_18959480_ChIP-ChIP_MESCs_Mouse1.52539277
63TOP2B_26459242_ChIP-Seq_MCF-7_Human1.51951532
64PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.51163717
65IGF1R_20145208_ChIP-Seq_DFB_Human1.49218141
66ELF1_17652178_ChIP-ChIP_JURKAT_Human1.47276975
67FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.45324672
68BP1_19119308_ChIP-ChIP_Hs578T_Human1.45093499
69PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.43928393
70YY1_21170310_ChIP-Seq_MESCs_Mouse1.43037035
71* GABP_19822575_ChIP-Seq_HepG2_Human1.43020141
72UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.41637079
73* JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.35967620
74SMAD4_21799915_ChIP-Seq_A2780_Human1.34380247
75FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.32855081
76YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.32773867
77* NELFA_20434984_ChIP-Seq_ESCs_Mouse1.32638378
78SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.32068193
79SMAD3_21741376_ChIP-Seq_EPCs_Human1.31707216
80RNF2_27304074_Chip-Seq_NSC_Mouse1.30697812
81* PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.30295524
82IKZF1_21737484_ChIP-ChIP_HCT116_Human1.27461724
83RNF2_27304074_Chip-Seq_ESCs_Mouse1.27229501
84ETS1_20019798_ChIP-Seq_JURKAT_Human1.27116427
85POU5F1_16153702_ChIP-ChIP_HESCs_Human1.26004054
86HOXB4_20404135_ChIP-ChIP_EML_Mouse1.24012029
87HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.24003276
88JUN_21703547_ChIP-Seq_K562_Human1.23701257
89* ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.23491924
90CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.23483774
91CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.22416261
92OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.21987851
93NANOG_16153702_ChIP-ChIP_HESCs_Human1.21182698
94MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.19348840
95PIAS1_25552417_ChIP-Seq_VCAP_Human1.18626723
96CDX2_19796622_ChIP-Seq_MESCs_Mouse1.17140638
97CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.16700162
98TP53_22573176_ChIP-Seq_HFKS_Human1.15267451
99NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.15095934
100PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.14922695
101GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.14682840
102SOX2_16153702_ChIP-ChIP_HESCs_Human1.14373215
103EWS_26573619_Chip-Seq_HEK293_Human1.11852595
104RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.11219380
105MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.10794225
106NR3C1_23031785_ChIP-Seq_PC12_Mouse1.09980834
107RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.08213800
108IRF1_19129219_ChIP-ChIP_H3396_Human1.07772149
109CREB1_15753290_ChIP-ChIP_HEK293T_Human1.07624880
110PCGF2_27294783_Chip-Seq_ESCs_Mouse1.07388796
111AR_21572438_ChIP-Seq_LNCaP_Human1.07027814
112FLI1_27457419_Chip-Seq_LIVER_Mouse1.06151914
113SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.06116738
114GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.01223601
115CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse1.00866436
116RARB_27405468_Chip-Seq_BRAIN_Mouse0.98701125
117REST_19997604_ChIP-ChIP_NEURONS_Mouse0.97802507
118TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.97586844
119HTT_18923047_ChIP-ChIP_STHdh_Human0.97047292
120NANOG_18555785_Chip-Seq_ESCs_Mouse0.96653115
121POU5F1_18555785_ChIP-Seq_MESCs_Mouse0.96307740
122AR_25329375_ChIP-Seq_VCAP_Human0.95538050
123BCAT_22108803_ChIP-Seq_LS180_Human0.95053963
124RUNX2_22187159_ChIP-Seq_PCA_Human0.94905141
125EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.94838973
126EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse0.94301849
127CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.93386781
128PRDM14_20953172_ChIP-Seq_ESCs_Human0.93202721
129SRF_21415370_ChIP-Seq_HL-1_Mouse0.91236184
130ZFP42_18358816_ChIP-ChIP_MESCs_Mouse0.89877293
131ELK1_22589737_ChIP-Seq_MCF10A_Human0.89751477
132HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse0.89291093
133THAP11_20581084_ChIP-Seq_MESCs_Mouse0.89036485
134ERG_21242973_ChIP-ChIP_JURKAT_Human0.88499178
135P53_22387025_ChIP-Seq_ESCs_Mouse0.86639557
136SOX2_19829295_ChIP-Seq_ESCs_Human0.86351168
137NANOG_19829295_ChIP-Seq_ESCs_Human0.86351168
138FOXA1_27270436_Chip-Seq_PROSTATE_Human0.82682795
139FOXA1_25329375_ChIP-Seq_VCAP_Human0.82682795
140SOX2_18555785_ChIP-Seq_MESCs_Mouse0.80564214
141CEBPB_23403033_ChIP-Seq_LIVER_Mouse0.80123669
142SIN3B_21632747_ChIP-Seq_MESCs_Mouse0.78534371
143RBPJ_22232070_ChIP-Seq_NCS_Mouse0.78521052
144IRF4_20064451_ChIP-Seq_CD4+T_Mouse0.77137305
145CBP_20019798_ChIP-Seq_JUKART_Human0.77137305
146PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse0.77077545
147TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat0.76993238
148* MYCN_18555785_ChIP-Seq_MESCs_Mouse0.72862162
149SUZ12_27294783_Chip-Seq_NPCs_Mouse0.72510996
150NANOG_18358816_ChIP-ChIP_MESCs_Mouse0.71407163
151NFE2_27457419_Chip-Seq_LIVER_Mouse0.70790334

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003880_abnormal_central_pattern5.39446985
2MP0002837_dystrophic_cardiac_calcinosis3.91045655
3MP0001529_abnormal_vocalization3.43527496
4MP0006276_abnormal_autonomic_nervous3.06305367
5MP0003635_abnormal_synaptic_transmissio2.74471024
6MP0001968_abnormal_touch/_nociception2.73508549
7MP0009745_abnormal_behavioral_response2.70319108
8MP0004859_abnormal_synaptic_plasticity2.67788884
9MP0009379_abnormal_foot_pigmentation2.62001750
10MP0002736_abnormal_nociception_after2.57085408
11MP0002064_seizures2.56926088
12MP0009046_muscle_twitch2.50510597
13MP0001440_abnormal_grooming_behavior2.48538310
14MP0001905_abnormal_dopamine_level2.48460234
15MP0003186_abnormal_redox_activity2.43356981
16MP0002272_abnormal_nervous_system2.29846127
17MP0002572_abnormal_emotion/affect_behav2.28528198
18MP0003806_abnormal_nucleotide_metabolis2.25159529
19MP0002063_abnormal_learning/memory/cond2.21995130
20MP0003011_delayed_dark_adaptation2.15838575
21MP0002938_white_spotting2.09128034
22MP0004270_analgesia2.08024663
23MP0004142_abnormal_muscle_tone2.01736032
24MP0000751_myopathy2.00294395
25MP0002734_abnormal_mechanical_nocicepti1.99147529
26MP0001486_abnormal_startle_reflex1.97504759
27MP0002735_abnormal_chemical_nociception1.94880654
28MP0004215_abnormal_myocardial_fiber1.94435243
29MP0001501_abnormal_sleep_pattern1.93961227
30MP0005423_abnormal_somatic_nervous1.90246546
31MP0008058_abnormal_DNA_repair1.86790755
32MP0005386_behavior/neurological_phenoty1.82507681
33MP0004924_abnormal_behavior1.82507681
34MP0006036_abnormal_mitochondrial_physio1.81714959
35MP0002067_abnormal_sensory_capabilities1.78875948
36MP0008877_abnormal_DNA_methylation1.77125750
37MP0006035_abnormal_mitochondrial_morpho1.74617118
38MP0003646_muscle_fatigue1.73197572
39MP0001970_abnormal_pain_threshold1.71807936
40MP0001984_abnormal_olfaction1.71552151
41MP0002733_abnormal_thermal_nociception1.70741055
42MP0003718_maternal_effect1.68636554
43MP0005084_abnormal_gallbladder_morpholo1.62577809
44MP0004957_abnormal_blastocyst_morpholog1.55943014
45MP0004145_abnormal_muscle_electrophysio1.55379265
46MP0002184_abnormal_innervation1.53481800
47MP0003122_maternal_imprinting1.51532061
48MP0001188_hyperpigmentation1.51302123
49MP0005379_endocrine/exocrine_gland_phen1.50041846
50MP0002638_abnormal_pupillary_reflex1.49517921
51MP0004147_increased_porphyrin_level1.47601149
52MP0002163_abnormal_gland_morphology1.44292916
53MP0002876_abnormal_thyroid_physiology1.43929656
54MP0000778_abnormal_nervous_system1.42451103
55MP0005645_abnormal_hypothalamus_physiol1.41764942
56MP0002822_catalepsy1.40685397
57MP0003121_genomic_imprinting1.39429312
58MP0001293_anophthalmia1.36915246
59MP0005253_abnormal_eye_physiology1.35586242
60MP0003329_amyloid_beta_deposits1.35137744
61MP0010386_abnormal_urinary_bladder1.34755634
62MP0004036_abnormal_muscle_relaxation1.34004889
63MP0002557_abnormal_social/conspecific_i1.32001826
64MP0000013_abnormal_adipose_tissue1.28524797
65MP0004484_altered_response_of1.27652224
66MP0003890_abnormal_embryonic-extraembry1.25965592
67MP0005535_abnormal_body_temperature1.24836580
68MP0002090_abnormal_vision1.23567471
69MP0003137_abnormal_impulse_conducting1.23338113
70MP0004742_abnormal_vestibular_system1.23199513
71MP0002332_abnormal_exercise_endurance1.22233295
72MP0006072_abnormal_retinal_apoptosis1.22058286
73MP0003941_abnormal_skin_development1.20948594
74MP0003567_abnormal_fetal_cardiomyocyte1.20523982
75MP0002277_abnormal_respiratory_mucosa1.19467476
76MP0004133_heterotaxia1.19459574
77MP0009697_abnormal_copulation1.18294782
78MP0003136_yellow_coat_color1.17535015
79MP0005409_darkened_coat_color1.17257150
80MP0003123_paternal_imprinting1.16470864
81MP0008995_early_reproductive_senescence1.15022428
82MP0002066_abnormal_motor_capabilities/c1.13670861
83MP0004085_abnormal_heartbeat1.13546922
84MP0003786_premature_aging1.13148190
85MP0001727_abnormal_embryo_implantation1.12893101
86MP0002160_abnormal_reproductive_system1.11922169
87MP0008875_abnormal_xenobiotic_pharmacok1.10378187
88MP0001502_abnormal_circadian_rhythm1.09008336
89MP0005551_abnormal_eye_electrophysiolog1.08807488
90MP0003693_abnormal_embryo_hatching1.08525899
91MP0003787_abnormal_imprinting1.08433118
92MP0000749_muscle_degeneration1.08414532
93MP0005332_abnormal_amino_acid1.00676854
94MP0005646_abnormal_pituitary_gland0.98889579
95MP0008872_abnormal_physiological_respon0.98230409
96MP0002882_abnormal_neuron_morphology0.98076150
97MP0001485_abnormal_pinna_reflex0.97828298
98MP0005330_cardiomyopathy0.97433893
99MP0003315_abnormal_perineum_morphology0.97193419
100MP0004043_abnormal_pH_regulation0.96933364
101MP0002234_abnormal_pharynx_morphology0.96449148
102MP0004084_abnormal_cardiac_muscle0.96325747
103MP0005389_reproductive_system_phenotype0.95239078
104MP0010094_abnormal_chromosome_stability0.95197401
105MP0002972_abnormal_cardiac_muscle0.95159653
106MP0002751_abnormal_autonomic_nervous0.95100602
107MP0003195_calcinosis0.94385538
108MP0005408_hypopigmentation0.93492064
109MP0005171_absent_coat_pigmentation0.92114364
110MP0005620_abnormal_muscle_contractility0.92086264
111MP0001764_abnormal_homeostasis0.89883308
112MP0000049_abnormal_middle_ear0.89563277
113MP0001963_abnormal_hearing_physiology0.88521239
114MP0002210_abnormal_sex_determination0.87076130
115MP0000955_abnormal_spinal_cord0.86920827
116MP0001919_abnormal_reproductive_system0.85763670
117MP0002229_neurodegeneration0.85643535
118MP0006292_abnormal_olfactory_placode0.84517897
119MP0002909_abnormal_adrenal_gland0.83718527
120MP0008932_abnormal_embryonic_tissue0.83224416
121MP0008569_lethality_at_weaning0.82101222
122MP0001664_abnormal_digestion0.81259053
123MP0003938_abnormal_ear_development0.80735774
124MP0005195_abnormal_posterior_eye0.80240332
125MP0000631_abnormal_neuroendocrine_gland0.79956113
126MP0002752_abnormal_somatic_nervous0.79850553
127MP0003077_abnormal_cell_cycle0.79691876
128MP0010030_abnormal_orbit_morphology0.79518854
129MP0002106_abnormal_muscle_physiology0.78220192
130MP0003879_abnormal_hair_cell0.77840491
131MP0000026_abnormal_inner_ear0.77527712
132MP0002102_abnormal_ear_morphology0.75949508
133MP0005499_abnormal_olfactory_system0.74492501
134MP0005394_taste/olfaction_phenotype0.74492501
135MP0004811_abnormal_neuron_physiology0.71400562
136MP0000538_abnormal_urinary_bladder0.70938272
137MP0000372_irregular_coat_pigmentation0.70190251
138MP0000747_muscle_weakness0.68946524
139MP0001986_abnormal_taste_sensitivity0.68265970
140MP0000230_abnormal_systemic_arterial0.67693559
141MP0005369_muscle_phenotype0.66597242
142MP0002069_abnormal_eating/drinking_beha0.65061491
143MP0008789_abnormal_olfactory_epithelium0.64206544
144MP0000920_abnormal_myelination0.63748982

Predicted human phenotypes

RankGene SetZ-score
1Acute necrotizing encephalopathy (HP:0006965)7.81999937
2Abnormal mitochondria in muscle tissue (HP:0008316)7.09921771
3Progressive macrocephaly (HP:0004481)6.77360066
4Mitochondrial inheritance (HP:0001427)6.62535727
5Acute encephalopathy (HP:0006846)6.39363699
6Increased CSF lactate (HP:0002490)5.61107513
7Increased hepatocellular lipid droplets (HP:0006565)5.36622825
8Hepatocellular necrosis (HP:0001404)5.15798661
9Lipid accumulation in hepatocytes (HP:0006561)4.83381431
10Cerebral edema (HP:0002181)4.59037357
11Renal Fanconi syndrome (HP:0001994)4.54450475
12Hepatic necrosis (HP:0002605)4.42610264
13Optic disc pallor (HP:0000543)4.20484381
14Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)4.19532639
15Increased intramyocellular lipid droplets (HP:0012240)4.15253812
16Focal motor seizures (HP:0011153)4.10034458
17Exercise intolerance (HP:0003546)3.99117782
18Respiratory failure (HP:0002878)3.82176405
19Muscle abnormality related to mitochondrial dysfunction (HP:0003800)3.75214546
20Lactic acidosis (HP:0003128)3.72528308
21Congenital, generalized hypertrichosis (HP:0004540)3.69863537
22Leukodystrophy (HP:0002415)3.66918085
23Increased serum pyruvate (HP:0003542)3.56920574
24Abnormality of glycolysis (HP:0004366)3.56920574
25Increased muscle lipid content (HP:0009058)3.52753807
26Macrocytic anemia (HP:0001972)3.36535745
27Exertional dyspnea (HP:0002875)3.29655524
28Abnormal activity of mitochondrial respiratory chain (HP:0011922)3.24427614
29Decreased activity of mitochondrial respiratory chain (HP:0008972)3.24427614
303-Methylglutaconic aciduria (HP:0003535)3.13004819
31Increased serum lactate (HP:0002151)3.10931629
32Reticulocytopenia (HP:0001896)3.06660278
33Abnormality of renal resorption (HP:0011038)3.02395312
34Pheochromocytoma (HP:0002666)2.99212876
35X-linked dominant inheritance (HP:0001423)2.98604264
36Neuroendocrine neoplasm (HP:0100634)2.93551889
37Atonic seizures (HP:0010819)2.92970480
38Respiratory difficulties (HP:0002880)2.92390262
39Congenital nonbullous ichthyosiform erythroderma (HP:0007479)2.86346704
40Myokymia (HP:0002411)2.79219264
41Visual hallucinations (HP:0002367)2.67169052
42Absence seizures (HP:0002121)2.65310710
43Methylmalonic acidemia (HP:0002912)2.61643036
44Hyperphosphaturia (HP:0003109)2.55296050
45Muscle hypertrophy of the lower extremities (HP:0008968)2.54989106
46Focal seizures (HP:0007359)2.54680698
47Hyperventilation (HP:0002883)2.47202579
48Epileptic encephalopathy (HP:0200134)2.46120826
49Dialeptic seizures (HP:0011146)2.45617553
50Oral leukoplakia (HP:0002745)2.43745647
51Septo-optic dysplasia (HP:0100842)2.42467962
52Aplastic anemia (HP:0001915)2.42018109
53Calf muscle hypertrophy (HP:0008981)2.32488137
54Methylmalonic aciduria (HP:0012120)2.28255965
55Glycosuria (HP:0003076)2.27501251
56Abnormality of urine glucose concentration (HP:0011016)2.27501251
57Emotional lability (HP:0000712)2.26767469
58Pancreatic fibrosis (HP:0100732)2.25356940
59Sudden death (HP:0001699)2.25224572
60Anxiety (HP:0000739)2.23361003
61Limb dystonia (HP:0002451)2.21045833
62Pallor (HP:0000980)2.20791908
63CNS demyelination (HP:0007305)2.20505811
64Medial flaring of the eyebrow (HP:0010747)2.20166009
65Parakeratosis (HP:0001036)2.14786905
66Pancreatic cysts (HP:0001737)2.14402689
67Febrile seizures (HP:0002373)2.14283037
68Generalized aminoaciduria (HP:0002909)2.13078848
69Abnormal ciliary motility (HP:0012262)2.11979633
70Abnormality of cells of the erythroid lineage (HP:0012130)2.11466019
71Abnormality of midbrain morphology (HP:0002418)2.10563500
72Molar tooth sign on MRI (HP:0002419)2.10563500
73Abnormal urine phosphate concentration (HP:0012599)2.10280040
74Generalized tonic-clonic seizures (HP:0002069)2.08179112
75Lethargy (HP:0001254)2.07005887
76Gait imbalance (HP:0002141)2.06888123
77Progressive inability to walk (HP:0002505)2.06031560
78Conjunctival hamartoma (HP:0100780)2.04482431
79Amblyopia (HP:0000646)2.03596042
80Hyperglycinemia (HP:0002154)2.02066817
81Abnormal pupillary function (HP:0007686)2.02007658
82Cerebral hemorrhage (HP:0001342)2.00699088
83Broad-based gait (HP:0002136)1.99004153
84True hermaphroditism (HP:0010459)1.98956431
85Type I transferrin isoform profile (HP:0003642)1.98846231
86Delusions (HP:0000746)1.97016934
87Congenital primary aphakia (HP:0007707)1.93336028
88Abnormality of the labia minora (HP:0012880)1.92580356
89Colon cancer (HP:0003003)1.90772914
90Sclerocornea (HP:0000647)1.87380270
91Renal tubular dysfunction (HP:0000124)1.86076682
92Abnormality of alanine metabolism (HP:0010916)1.85775232
93Hyperalaninemia (HP:0003348)1.85775232
94Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.85775232
95Abnormality of serum amino acid levels (HP:0003112)1.84286476
96Absent septum pellucidum (HP:0001331)1.81695546
97Abnormal respiratory motile cilium morphology (HP:0005938)1.81317313
98Abnormal respiratory epithelium morphology (HP:0012253)1.81317313
99Hypothermia (HP:0002045)1.78950981
100Abnormality of the anterior horn cell (HP:0006802)1.78878132
101Degeneration of anterior horn cells (HP:0002398)1.78878132
102Nephrogenic diabetes insipidus (HP:0009806)1.78121745
103Abnormality of methionine metabolism (HP:0010901)1.77504673
104Palpitations (HP:0001962)1.77353228
105Abnormal number of erythroid precursors (HP:0012131)1.73074427
106Stenosis of the external auditory canal (HP:0000402)1.72800780
107Congenital ichthyosiform erythroderma (HP:0007431)1.72668371
108Retinal dysplasia (HP:0007973)1.72615073
109Inability to walk (HP:0002540)1.71484953
110Abnormal respiratory motile cilium physiology (HP:0012261)1.70561237
111Gliosis (HP:0002171)1.68712897
112Cerebral inclusion bodies (HP:0100314)1.67706603
113Progressive external ophthalmoplegia (HP:0000590)1.66667602
114Delayed gross motor development (HP:0002194)1.66644209
115Reduced antithrombin III activity (HP:0001976)1.65010985
116Blindness (HP:0000618)1.64421194
117Polyphagia (HP:0002591)1.63700728
118Esotropia (HP:0000565)1.63689297
119Abnormality of aspartate family amino acid metabolism (HP:0010899)1.63459567
120Vomiting (HP:0002013)1.63404451
121Vaginal atresia (HP:0000148)1.63346538
122Male pseudohermaphroditism (HP:0000037)1.63324028
123Poor suck (HP:0002033)1.63307249
124Amniotic constriction ring (HP:0009775)1.62453653
125Abnormality of placental membranes (HP:0011409)1.62453653
126Genital tract atresia (HP:0001827)1.61679833
127Abnormality of dicarboxylic acid metabolism (HP:0010995)1.61566478
128Dicarboxylic aciduria (HP:0003215)1.61566478
129Rimmed vacuoles (HP:0003805)1.60507506
130Syncope (HP:0001279)1.59357115
131Abnormality of the calf musculature (HP:0001430)1.59241905
132Myotonia (HP:0002486)1.59173105
133Nephronophthisis (HP:0000090)1.56757371
134Optic nerve hypoplasia (HP:0000609)1.56209742
135Aplasia/hypoplasia of the uterus (HP:0008684)1.54069318
136Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.50509711
137Pendular nystagmus (HP:0012043)1.50247257
138Pancytopenia (HP:0001876)1.48492513
139Megaloblastic anemia (HP:0001889)1.47644992
140Abnormality of the septum pellucidum (HP:0007375)1.47250314
141Cerebral hypomyelination (HP:0006808)1.46855284

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAP3K124.01095208
2VRK23.95253517
3NME13.51461811
4PNCK3.45645786
5MAP2K72.81572728
6CASK2.80054307
7RIPK42.62330089
8MAP3K42.60655611
9NTRK32.52834305
10EPHA42.49561528
11ARAF2.48685144
12BUB12.44536837
13ZAK2.28520017
14CDC72.21525054
15MYLK2.11005759
16NEK12.05397102
17GRK72.04587679
18GRK51.95367610
19BMPR21.82657689
20SRPK11.80775756
21MUSK1.80318417
22MAP2K41.78381785
23STK391.76407727
24STK161.71971449
25PLK21.69949761
26TNIK1.68062233
27MARK11.64960770
28OXSR11.61578985
29MST41.56665533
30TRIM281.53933519
31WNK41.51757722
32MINK11.48955071
33MAP3K91.46074166
34CDK191.41588138
35MAP4K21.40893372
36NME21.38574708
37TAF11.36223238
38OBSCN1.35867846
39PLK31.34815924
40NUAK11.32734171
41FGR1.31854243
42CAMK2A1.29950510
43BCR1.29357549
44ADRBK21.28818846
45PLK41.25008302
46CAMK2B1.19580146
47GRK11.18040511
48WNK31.18039136
49BMPR1B1.14268576
50PBK1.14071745
51MAPK131.13830376
52UHMK11.12682706
53CAMK2D1.09007111
54EIF2AK11.07788474
55PTK2B1.06799049
56BCKDK1.05912037
57WEE11.04415997
58NTRK21.04233000
59CSNK1G11.04051736
60DYRK31.03166691
61MKNK10.98716235
62ERBB30.92536711
63ADRBK10.92048221
64PHKG20.91012052
65PHKG10.91012052
66PLK10.90828708
67PRKCG0.90574225
68LIMK10.90290247
69DAPK10.88307121
70PRKCE0.87885180
71VRK10.87065537
72MKNK20.86620829
73BRAF0.85604310
74MAPKAPK50.82942403
75CDK50.81026683
76TTK0.80269545
77CAMK2G0.80163580
78GRK60.79660273
79NTRK10.78807273
80ABL20.78392377
81FES0.76980158
82PDK30.76856657
83PDK40.76856657
84INSRR0.75982231
85PAK30.75360422
86TSSK60.74590422
87CSNK1A1L0.72171561
88AURKB0.71913654
89KSR10.71873675
90CSNK2A20.71822159
91TESK10.70524507
92CHEK20.68366372
93PINK10.67591627
94ROCK20.67114257
95RPS6KA50.66976696
96KSR20.66619149
97RAF10.65915810
98DAPK30.63937742
99PRKACA0.63503803
100CSNK2A10.62819158
101CDK140.60062427
102AURKA0.59132939
103DYRK20.58346951
104BRSK20.56988888
105DYRK1A0.56976830
106DAPK20.56717910
107PKN10.56030325
108PAK40.55835263
109CDK180.53435629
110IRAK20.52553563
111FRK0.52205902
112CSNK1E0.51795301
113CDK150.50385023
114MAP3K130.50101857
115CSNK1G30.49297987
116TLK10.48337590
117EIF2AK20.48119969
118CDK80.47096159
119CSNK1G20.46361844
120ILK0.46189994
121CDK11A0.45832179
122CSNK1A10.45532521
123EIF2AK30.45249085
124MAPK120.45084315
125PDK20.42793482
126EPHB20.42277915
127CDK30.41405431
128PIM20.40392536
129PIK3CA0.40377399
130MOS0.38468677
131STK38L0.38017978
132MAPK150.36817219
133PAK60.36532903
134MAP2K10.35707286
135PRKCQ0.34227454
136MAP3K60.32792833
137PRKCA0.32491818
138CAMK10.30787111
139PRKG10.30453868
140PIK3CG0.29613118
141LMTK20.28904076
142CCNB10.28480116
143CAMKK20.28322407
144ERBB40.27570448

Predicted pathways (KEGG)

RankGene SetZ-score
1Oxidative phosphorylation_Homo sapiens_hsa001906.76064584
2Parkinsons disease_Homo sapiens_hsa050125.66699907
3Alzheimers disease_Homo sapiens_hsa050104.53525256
4Huntingtons disease_Homo sapiens_hsa050164.01793447
5Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049323.53148779
6Cardiac muscle contraction_Homo sapiens_hsa042603.38257352
7Collecting duct acid secretion_Homo sapiens_hsa049662.64324402
8Nicotine addiction_Homo sapiens_hsa050332.60395929
9Ribosome_Homo sapiens_hsa030102.44745214
10Proteasome_Homo sapiens_hsa030502.27534994
11Mismatch repair_Homo sapiens_hsa034301.99957633
12Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.94953666
13Protein export_Homo sapiens_hsa030601.88451837
14Homologous recombination_Homo sapiens_hsa034401.87623393
15Synaptic vesicle cycle_Homo sapiens_hsa047211.84870012
16Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.79148545
17Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.75995515
18Vibrio cholerae infection_Homo sapiens_hsa051101.61531557
19GABAergic synapse_Homo sapiens_hsa047271.52899093
20Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.49719349
21DNA replication_Homo sapiens_hsa030301.49485881
22Spliceosome_Homo sapiens_hsa030401.44871949
23Basal transcription factors_Homo sapiens_hsa030221.41175155
24Serotonergic synapse_Homo sapiens_hsa047261.37369617
25Nucleotide excision repair_Homo sapiens_hsa034201.35081120
26RNA degradation_Homo sapiens_hsa030181.34439936
27Taste transduction_Homo sapiens_hsa047421.31745432
28RNA polymerase_Homo sapiens_hsa030201.29949837
29Morphine addiction_Homo sapiens_hsa050321.27725721
30Amphetamine addiction_Homo sapiens_hsa050311.20012393
31Circadian entrainment_Homo sapiens_hsa047131.18877208
32Long-term potentiation_Homo sapiens_hsa047201.18540116
33Folate biosynthesis_Homo sapiens_hsa007901.18076429
34Glutamatergic synapse_Homo sapiens_hsa047241.17280308
35Fatty acid elongation_Homo sapiens_hsa000621.13530296
36Dopaminergic synapse_Homo sapiens_hsa047281.08119300
37Pyruvate metabolism_Homo sapiens_hsa006201.07663234
38Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.05172056
39Sulfur metabolism_Homo sapiens_hsa009201.02929734
40RNA transport_Homo sapiens_hsa030130.99863042
41Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.97676978
42Renin secretion_Homo sapiens_hsa049240.97643779
43Fanconi anemia pathway_Homo sapiens_hsa034600.94517790
44Long-term depression_Homo sapiens_hsa047300.92510079
45Olfactory transduction_Homo sapiens_hsa047400.91729867
46Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.90833132
47One carbon pool by folate_Homo sapiens_hsa006700.90614632
48Calcium signaling pathway_Homo sapiens_hsa040200.87733051
49Phototransduction_Homo sapiens_hsa047440.86894462
50Rheumatoid arthritis_Homo sapiens_hsa053230.86266560
51Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.86256165
52Salivary secretion_Homo sapiens_hsa049700.85937623
53Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.84816862
54Propanoate metabolism_Homo sapiens_hsa006400.82530445
55Butanoate metabolism_Homo sapiens_hsa006500.82330832
56Gastric acid secretion_Homo sapiens_hsa049710.72441071
57Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.72111097
58Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.71455237
59Cholinergic synapse_Homo sapiens_hsa047250.71001201
60Insulin secretion_Homo sapiens_hsa049110.70292728
61Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.69014138
62Cocaine addiction_Homo sapiens_hsa050300.68361619
63Base excision repair_Homo sapiens_hsa034100.68349387
64Maturity onset diabetes of the young_Homo sapiens_hsa049500.67679635
65Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.66289706
66Metabolic pathways_Homo sapiens_hsa011000.66088524
67Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.65704297
68Chemical carcinogenesis_Homo sapiens_hsa052040.65620629
69Oxytocin signaling pathway_Homo sapiens_hsa049210.65583325
70Tryptophan metabolism_Homo sapiens_hsa003800.63463915
71Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.62448912
72Phenylalanine metabolism_Homo sapiens_hsa003600.58741408
73Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.56535114
74Non-homologous end-joining_Homo sapiens_hsa034500.55334999
75Sulfur relay system_Homo sapiens_hsa041220.54301420
76Pentose and glucuronate interconversions_Homo sapiens_hsa000400.53946573
77Tyrosine metabolism_Homo sapiens_hsa003500.53543958
78Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.52137359
792-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.51426697
80Nitrogen metabolism_Homo sapiens_hsa009100.49483627
81Linoleic acid metabolism_Homo sapiens_hsa005910.47042329
82Fatty acid degradation_Homo sapiens_hsa000710.45878716
83SNARE interactions in vesicular transport_Homo sapiens_hsa041300.45725509
84Gap junction_Homo sapiens_hsa045400.45704686
85Type I diabetes mellitus_Homo sapiens_hsa049400.45054594
86Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.44804962
87Carbon metabolism_Homo sapiens_hsa012000.44652918
88Phagosome_Homo sapiens_hsa041450.44250350
89Retinol metabolism_Homo sapiens_hsa008300.43502429
90Dilated cardiomyopathy_Homo sapiens_hsa054140.43409980
91Vascular smooth muscle contraction_Homo sapiens_hsa042700.42708701
92Caffeine metabolism_Homo sapiens_hsa002320.42618362
93GnRH signaling pathway_Homo sapiens_hsa049120.42373731
94Systemic lupus erythematosus_Homo sapiens_hsa053220.41214030
95Selenocompound metabolism_Homo sapiens_hsa004500.40219923
96beta-Alanine metabolism_Homo sapiens_hsa004100.40091207
97Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.39721185
98Primary bile acid biosynthesis_Homo sapiens_hsa001200.38843736
99Aldosterone synthesis and secretion_Homo sapiens_hsa049250.38679402
100Vitamin digestion and absorption_Homo sapiens_hsa049770.37139107
101African trypanosomiasis_Homo sapiens_hsa051430.35677970
102Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.34692043
103Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.34482661
104Pyrimidine metabolism_Homo sapiens_hsa002400.34012499
105Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.33724763
106Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.33640641
107Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.33528679
108Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.33159448
109Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.32330052
110Cell cycle_Homo sapiens_hsa041100.32225484
111Ether lipid metabolism_Homo sapiens_hsa005650.32009281
112alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.31873648
113Mineral absorption_Homo sapiens_hsa049780.31567187
114Fat digestion and absorption_Homo sapiens_hsa049750.31351904
115Vitamin B6 metabolism_Homo sapiens_hsa007500.31325623
116Fatty acid metabolism_Homo sapiens_hsa012120.30507917
117Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.30435225
118Asthma_Homo sapiens_hsa053100.30138792
119Alcoholism_Homo sapiens_hsa050340.30112233
120Axon guidance_Homo sapiens_hsa043600.29497535
121Purine metabolism_Homo sapiens_hsa002300.28976945
122Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.28366230
123cGMP-PKG signaling pathway_Homo sapiens_hsa040220.28141042
124Drug metabolism - other enzymes_Homo sapiens_hsa009830.27502995
125Steroid hormone biosynthesis_Homo sapiens_hsa001400.27472413
126Pancreatic secretion_Homo sapiens_hsa049720.25837158
127Melanogenesis_Homo sapiens_hsa049160.25337149
128Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.25131846
129cAMP signaling pathway_Homo sapiens_hsa040240.22504604
130Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.21779423
131Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.18032421
132Glutathione metabolism_Homo sapiens_hsa004800.15933628
133Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.14361157
134Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.13846451
135Estrogen signaling pathway_Homo sapiens_hsa049150.13497885
136Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.13017751
137Peroxisome_Homo sapiens_hsa041460.12950591
138Arginine and proline metabolism_Homo sapiens_hsa003300.12536018
139Regulation of autophagy_Homo sapiens_hsa041400.11771934
140Prion diseases_Homo sapiens_hsa050200.10643947
141Steroid biosynthesis_Homo sapiens_hsa001000.10411213
142Glucagon signaling pathway_Homo sapiens_hsa049220.10152909
143Arachidonic acid metabolism_Homo sapiens_hsa005900.09956056
144Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.09583044
145Cysteine and methionine metabolism_Homo sapiens_hsa002700.09539770
146Oocyte meiosis_Homo sapiens_hsa041140.09129670
147Graft-versus-host disease_Homo sapiens_hsa053320.08229410

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »