USP13

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1sarcomere organization (GO:0045214)8.05306217
2muscle filament sliding (GO:0030049)7.69337188
3actin-myosin filament sliding (GO:0033275)7.69337188
4negative regulation of potassium ion transmembrane transporter activity (GO:1901017)7.32556064
5cardiac myofibril assembly (GO:0055003)7.28456900
6positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316)7.27917674
7myofibril assembly (GO:0030239)7.02036774
8regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (GO:0010880)6.79302064
9regulation of skeletal muscle contraction (GO:0014819)6.62594620
10negative regulation of potassium ion transmembrane transport (GO:1901380)6.53604929
11sarcoplasmic reticulum calcium ion transport (GO:0070296)6.45603031
12plasma membrane repair (GO:0001778)6.41242661
13actin-mediated cell contraction (GO:0070252)6.38076869
14regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion (GO6.28168976
15cardiac muscle contraction (GO:0060048)6.08365749
16response to muscle activity (GO:0014850)5.93933864
17regulation of relaxation of muscle (GO:1901077)5.75766143
18regulation of ryanodine-sensitive calcium-release channel activity (GO:0060314)5.75755466
19regulation of cell communication by electrical coupling (GO:0010649)5.73591254
20regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882)5.67449595
21tricarboxylic acid cycle (GO:0006099)5.60304165
22striated muscle contraction (GO:0006941)5.46622367
23regulation of actin filament-based movement (GO:1903115)5.46301134
24cardiac muscle cell development (GO:0055013)5.34031327
25regulation of acetyl-CoA biosynthetic process from pyruvate (GO:0010510)5.29243815
26regulation of ventricular cardiac muscle cell membrane repolarization (GO:0060307)5.25299850
27actomyosin structure organization (GO:0031032)5.24334410
28skeletal muscle fiber development (GO:0048741)5.06021528
29cardiac cell development (GO:0055006)4.99453150
30carnitine shuttle (GO:0006853)4.93181533
31regulation of acyl-CoA biosynthetic process (GO:0050812)4.92426287
32ventricular cardiac muscle cell action potential (GO:0086005)4.88472508
33cardiac muscle hypertrophy (GO:0003300)4.80151410
34actin filament-based movement (GO:0030048)4.79652966
35regulation of membrane repolarization (GO:0060306)4.72980644
36skeletal muscle contraction (GO:0003009)4.72339856
37myotube cell development (GO:0014904)4.71669934
38cardiac muscle tissue morphogenesis (GO:0055008)4.71569443
39regulation of striated muscle contraction (GO:0006942)4.66610841
40regulation of sarcomere organization (GO:0060297)4.66508139
41response to stimulus involved in regulation of muscle adaptation (GO:0014874)4.65314755
42striated muscle hypertrophy (GO:0014897)4.64697572
43adult heart development (GO:0007512)4.60434971
44cell communication by electrical coupling involved in cardiac conduction (GO:0086064)4.60038667
45regulation of cofactor metabolic process (GO:0051193)4.52752389
46regulation of coenzyme metabolic process (GO:0051196)4.52752389
47cell communication involved in cardiac conduction (GO:0086065)4.36282619
48muscle tissue morphogenesis (GO:0060415)4.32611762
49heart contraction (GO:0060047)4.30727562
50heart process (GO:0003015)4.30727562
51ventricular cardiac muscle tissue morphogenesis (GO:0055010)4.25674194
52glucan catabolic process (GO:0009251)4.25463398
53positive regulation of calcium ion transmembrane transporter activity (GO:1901021)4.19166144
54bundle of His cell to Purkinje myocyte communication (GO:0086069)4.15561191
55fatty acid transmembrane transport (GO:1902001)4.14772435
56glucan biosynthetic process (GO:0009250)4.11564388
57glycogen biosynthetic process (GO:0005978)4.11564388
58muscle hypertrophy (GO:0014896)4.06521515
59cell communication by electrical coupling (GO:0010644)4.00910944
60heart trabecula formation (GO:0060347)3.99845939
61cellular polysaccharide catabolic process (GO:0044247)3.97746872
62skeletal muscle tissue development (GO:0007519)3.95617657
63regulation of the force of heart contraction (GO:0002026)3.94881085
64muscle contraction (GO:0006936)3.92865622
65mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.92403945
66mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.92181289
67muscle cell cellular homeostasis (GO:0046716)3.91957317
68regulation of calcium ion transmembrane transporter activity (GO:1901019)3.89983140
69regulation of calcium ion transmembrane transport (GO:1903169)3.89983140
70creatine metabolic process (GO:0006600)3.87135102
71skeletal muscle adaptation (GO:0043501)3.83994668
72cardiac muscle cell action potential (GO:0086001)3.77822818
73cardiac muscle cell action potential involved in contraction (GO:0086002)3.76540153
74regulation of cardiac muscle contraction (GO:0055117)3.76059383
75negative regulation of potassium ion transport (GO:0043267)3.75337575
76response to inactivity (GO:0014854)3.73059409
77membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.72251660
78respiratory electron transport chain (GO:0022904)3.66457808
79regulation of cardiac muscle cell contraction (GO:0086004)3.65051397
80muscle cell fate commitment (GO:0042693)3.64261882
81positive regulation of cation channel activity (GO:2001259)3.64212384
82regulation of heart rate (GO:0002027)3.63230467
83muscle system process (GO:0003012)3.61865294
84negative regulation of protein localization to cell surface (GO:2000009)3.61836470
85energy coupled proton transport, down electrochemical gradient (GO:0015985)3.61255537
86ATP synthesis coupled proton transport (GO:0015986)3.61255537
87regulation of sulfur metabolic process (GO:0042762)3.60605090
88striated muscle cell development (GO:0055002)3.57658769
89carnitine transmembrane transport (GO:1902603)3.57385842
90electron transport chain (GO:0022900)3.55289715
91polysaccharide catabolic process (GO:0000272)3.53524125
92NADH metabolic process (GO:0006734)3.49209810
93cardiac muscle adaptation (GO:0014887)3.49135115
94cardiac muscle hypertrophy in response to stress (GO:0014898)3.49135115
95muscle hypertrophy in response to stress (GO:0003299)3.49135115
96striated muscle adaptation (GO:0014888)3.48358984
97skeletal muscle tissue regeneration (GO:0043403)3.44933711
98detection of calcium ion (GO:0005513)3.44128527
99muscle structure development (GO:0061061)3.43876314
100cardiac conduction (GO:0061337)3.42005392
101regulation of calcineurin-NFAT signaling cascade (GO:0070884)3.42000446
102relaxation of cardiac muscle (GO:0055119)3.41701015
103muscle organ development (GO:0007517)3.41508345
104IMP metabolic process (GO:0046040)3.40518308
1052-oxoglutarate metabolic process (GO:0006103)3.38549993
106myotube differentiation (GO:0014902)3.37296479
107regulation of heart contraction (GO:0008016)3.34277472
108glycogen metabolic process (GO:0005977)3.33999825
109glycogen catabolic process (GO:0005980)3.32436633
110muscle cell development (GO:0055001)3.31083699
111muscle adaptation (GO:0043500)3.29733087
112muscle fiber development (GO:0048747)3.28659292
113regulation of heart rate by cardiac conduction (GO:0086091)3.27776547
114positive regulation of potassium ion transmembrane transport (GO:1901381)3.27705316
115positive regulation of potassium ion transmembrane transporter activity (GO:1901018)3.26537322
116regulation of ATP catabolic process (GO:1903289)3.26423779
117regulation of ATPase activity (GO:0043462)3.26423779
118cellular glucan metabolic process (GO:0006073)3.24377457
119glucan metabolic process (GO:0044042)3.24377457
120oxidative phosphorylation (GO:0006119)3.24028294
121amino-acid betaine transport (GO:0015838)3.21906468
122carnitine transport (GO:0015879)3.21906468
123regulation of muscle contraction (GO:0006937)3.20631074
124striated muscle atrophy (GO:0014891)3.16343739
125response to caffeine (GO:0031000)3.08164494
126negative regulation of phosphoprotein phosphatase activity (GO:0032515)3.07874313
127gluconeogenesis (GO:0006094)3.05768229
128myoblast fusion (GO:0007520)3.00491742
129regulation of muscle system process (GO:0090257)2.99644717
130regulation of skeletal muscle cell differentiation (GO:2001014)2.98429582
131muscle atrophy (GO:0014889)2.97716619
132regulation of myoblast differentiation (GO:0045661)2.97292800
133positive regulation of myotube differentiation (GO:0010831)2.96632046
134response to activity (GO:0014823)2.96164437
135mitochondrial genome maintenance (GO:0000002)2.95055884
136negative regulation of calcium ion transmembrane transport (GO:1903170)2.92156247
137negative regulation of calcium ion transmembrane transporter activity (GO:1901020)2.92156247
138striated muscle tissue development (GO:0014706)2.91940435

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human4.68656931
2EP300_21415370_ChIP-Seq_HL-1_Mouse3.85682868
3ESRRB_18555785_ChIP-Seq_MESCs_Mouse3.82402797
4PPARG_19300518_ChIP-PET_3T3-L1_Mouse3.75053170
5RBPJ_22232070_ChIP-Seq_NCS_Mouse3.19215168
6* TBX20_22328084_ChIP-Seq_HEART_Mouse2.84236968
7* TBX20_22080862_ChIP-Seq_HEART_Mouse2.84236968
8ESR1_20079471_ChIP-ChIP_T-47D_Human2.77608895
9RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.46805114
10TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse2.32238743
11CDX2_19796622_ChIP-Seq_MESCs_Mouse2.30604159
12MEF2A_21415370_ChIP-Seq_HL-1_Mouse2.28237296
13ZNF263_19887448_ChIP-Seq_K562_Human2.28043512
14SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.08357012
15PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.98779294
16DROSHA_22980978_ChIP-Seq_HELA_Human1.96378128
17CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.95278378
18BP1_19119308_ChIP-ChIP_Hs578T_Human1.93584949
19SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.91564334
20RNF2_18974828_ChIP-Seq_MESCs_Mouse1.87406389
21EZH2_18974828_ChIP-Seq_MESCs_Mouse1.87406389
22* FOXM1_23109430_ChIP-Seq_U2OS_Human1.83304966
23EZH2_27304074_Chip-Seq_ESCs_Mouse1.81236053
24SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.79506991
25BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.74156635
26MTF2_20144788_ChIP-Seq_MESCs_Mouse1.73021721
27ZNF274_21170338_ChIP-Seq_K562_Hela1.70984131
28JARID2_20064375_ChIP-Seq_MESCs_Mouse1.70299690
29NFIB_24661679_ChIP-Seq_LUNG_Mouse1.69486265
30RARG_19884340_ChIP-ChIP_MEFs_Mouse1.60775280
31EZH2_27294783_Chip-Seq_ESCs_Mouse1.60374521
32* EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.56493256
33GBX2_23144817_ChIP-Seq_PC3_Human1.55217239
34KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.53868096
35RARB_27405468_Chip-Seq_BRAIN_Mouse1.52945980
36JARID2_20075857_ChIP-Seq_MESCs_Mouse1.47186676
37* GATA4_21415370_ChIP-Seq_HL-1_Mouse1.46697729
38CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.45549581
39ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.45009855
40ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.43925191
41SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.43556071
42NR3C1_23031785_ChIP-Seq_PC12_Mouse1.42891003
43IGF1R_20145208_ChIP-Seq_DFB_Human1.38750151
44AR_21572438_ChIP-Seq_LNCaP_Human1.38190854
45THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.37808487
46CTCF_27219007_Chip-Seq_Bcells_Human1.32254040
47SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.32192824
48PCGF2_27294783_Chip-Seq_ESCs_Mouse1.30579553
49SOX2_21211035_ChIP-Seq_LN229_Gbm1.30217818
50ESR2_21235772_ChIP-Seq_MCF-7_Human1.29458303
51SUZ12_27294783_Chip-Seq_ESCs_Mouse1.29249498
52BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.25948820
53RNF2_27304074_Chip-Seq_ESCs_Mouse1.23135327
54SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.22294703
55EED_16625203_ChIP-ChIP_MESCs_Mouse1.20315894
56CBX2_27304074_Chip-Seq_ESCs_Mouse1.20177878
57ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.20118904
58SALL1_21062744_ChIP-ChIP_HESCs_Human1.19010360
59CLOCK_20551151_ChIP-Seq_293T_Human1.16306634
60FLI1_27457419_Chip-Seq_LIVER_Mouse1.16220048
61SMAD4_21799915_ChIP-Seq_A2780_Human1.15865976
62GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.15616372
63SUZ12_27294783_Chip-Seq_NPCs_Mouse1.15314361
64* TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.14856124
65STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.14813954
66YAP1_20516196_ChIP-Seq_MESCs_Mouse1.14507779
67* TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.14300236
68NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.13793169
69HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.11763924
70SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.11641448
71EZH2_27294783_Chip-Seq_NPCs_Mouse1.10712931
72CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.09422668
73AR_21909140_ChIP-Seq_LNCAP_Human1.08425194
74PRDM14_21183938_ChIP-Seq_MESCs_Mouse1.08251586
75RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.07027365
76ZFP281_18757296_ChIP-ChIP_E14_Mouse1.06656505
77SOX9_26525672_Chip-Seq_HEART_Mouse1.06220491
78ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.04618245
79SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.04558396
80SMAD3_21741376_ChIP-Seq_HESCs_Human1.04368961
81ISL1_27105846_Chip-Seq_CPCs_Mouse1.04326145
82BCAT_22108803_ChIP-Seq_LS180_Human1.03396985
83SMAD4_21741376_ChIP-Seq_HESCs_Human1.02617974
84FOXM1_26456572_ChIP-Seq_MCF-7_Human1.02588860
85REST_18959480_ChIP-ChIP_MESCs_Mouse1.02426929
86TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.01521146
87SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.01029922
88VDR_22108803_ChIP-Seq_LS180_Human1.00811903
89* WT1_25993318_ChIP-Seq_PODOCYTE_Human1.00572275
90DNAJC2_21179169_ChIP-ChIP_NT2_Human0.99689635
91TRIM28_17542650_ChIP-ChIP_NTERA2_Human0.98443288
92CRX_20693478_ChIP-Seq_RETINA_Mouse0.97949184
93PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.97886175
94* EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human0.97700946
95PPARD_23208498_ChIP-Seq_MDA-MB-231_Human0.97230559
96PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human0.95222298
97CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse0.95180852
98AHR_22903824_ChIP-Seq_MCF-7_Human0.95033443
99EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human0.95018205
100WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse0.94530476
101CTBP1_25329375_ChIP-Seq_LNCAP_Human0.94232650
102E2F7_22180533_ChIP-Seq_HELA_Human0.93516448
103GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.93482392
104FUS_26573619_Chip-Seq_HEK293_Human0.92934750
105MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human0.92495889
106* WT1_19549856_ChIP-ChIP_CCG9911_Human0.92471809
107CTNNB1_20460455_ChIP-Seq_HCT116_Human0.92091102
108* AR_19668381_ChIP-Seq_PC3_Human0.91968859
109SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.91011876
110KDM2B_26808549_Chip-Seq_SUP-B15_Human0.90268470
111PCGF2_27294783_Chip-Seq_NPCs_Mouse0.90172016
112REST_21632747_ChIP-Seq_MESCs_Mouse0.89011618
113SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse0.88667843
114STAT3_19079543_ChIP-ChIP_MESCs_Mouse0.88497553
115MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.87413759
116OCT4_21477851_ChIP-Seq_ESCs_Mouse0.87382771
117* FOXA2_19822575_ChIP-Seq_HepG2_Human0.87271381
118NKX2-5_21415370_ChIP-Seq_HL-1_Mouse0.86946683
119SREBP1_19666523_ChIP-Seq_LIVER_Mouse0.86789624
120PHC1_16625203_ChIP-ChIP_MESCs_Mouse0.86621527
121RING1B_27294783_Chip-Seq_ESCs_Mouse0.86215351
122TRIM28_21343339_ChIP-Seq_HEK293_Human0.86029032
123FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human0.85973339
124SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.84963272
125NFE2L2_20460467_ChIP-Seq_MEFs_Mouse0.84785863
126NRF2_20460467_ChIP-Seq_MEFs_Mouse0.84785863
127GF1_26923725_Chip-Seq_HPCs_Mouse0.84256421
128POU3F2_20337985_ChIP-ChIP_501MEL_Human0.84253037
129SMAD3_21741376_ChIP-Seq_EPCs_Human0.83619840
130KDM2B_26808549_Chip-Seq_K562_Human0.83590718
131TAF15_26573619_Chip-Seq_HEK293_Human0.82733725
132* SALL4_18804426_ChIP-ChIP_MESCs_Mouse0.81672905
133NR0B1_18358816_ChIP-ChIP_MESCs_Mouse0.81545848
134PPARG_20176806_ChIP-Seq_3T3-L1_Mouse0.81539019
135YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse0.81091932
136FOXH1_21741376_ChIP-Seq_ESCs_Human0.81087057
137ARNT_22903824_ChIP-Seq_MCF-7_Human0.81028071
138TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.81004865
139TOP2B_26459242_ChIP-Seq_MCF-7_Human0.80592089
140TP63_22573176_ChIP-Seq_HFKS_Human0.80478921
141TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.80026818
142TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.80009639
143OCT4_20526341_ChIP-Seq_ESCs_Human0.79596467
144UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.79407025
145TP53_20018659_ChIP-ChIP_R1E_Mouse0.79222178
146KLF5_20875108_ChIP-Seq_MESCs_Mouse0.78557447
147* TCF4_23295773_ChIP-Seq_U87_Human0.77840129
148ZNF217_24962896_ChIP-Seq_MCF-7_Human0.77519388
149LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.76592042
150TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.76397516
151DMRT1_23473982_ChIP-Seq_TESTES_Mouse0.76367915
152PIAS1_25552417_ChIP-Seq_VCAP_Human0.75780306
153EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse0.75734652
154ER_23166858_ChIP-Seq_MCF-7_Human0.75286091
155CJUN_26792858_Chip-Seq_BT549_Human0.74295632
156* NR3C1_21868756_ChIP-Seq_MCF10A_Human0.74040650
157LXR_22158963_ChIP-Seq_LIVER_Mouse0.73574525

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002837_dystrophic_cardiac_calcinosis6.15903952
2MP0003646_muscle_fatigue5.79880717
3MP0000751_myopathy5.44375883
4MP0004084_abnormal_cardiac_muscle4.93999554
5MP0000749_muscle_degeneration4.49098248
6MP0004036_abnormal_muscle_relaxation4.32656219
7MP0004215_abnormal_myocardial_fiber4.22402119
8MP0004145_abnormal_muscle_electrophysio3.86727714
9MP0005330_cardiomyopathy3.43474466
10MP0004087_abnormal_muscle_fiber3.15830673
11MP0002106_abnormal_muscle_physiology2.91897779
12MP0005620_abnormal_muscle_contractility2.90231084
13MP0002972_abnormal_cardiac_muscle2.82993457
14MP0000750_abnormal_muscle_regeneration2.72067601
15MP0004130_abnormal_muscle_cell2.66385672
16MP0000747_muscle_weakness2.65542632
17MP0003137_abnormal_impulse_conducting2.61944091
18MP0002269_muscular_atrophy2.56271143
19MP0008775_abnormal_heart_ventricle2.48211236
20MP0004484_altered_response_of2.44032086
21MP0000759_abnormal_skeletal_muscle2.41171107
22MP0005369_muscle_phenotype2.41018816
23MP0010630_abnormal_cardiac_muscle2.22215919
24MP0001544_abnormal_cardiovascular_syste2.20005281
25MP0005385_cardiovascular_system_phenoty2.20005281
26MP0004233_abnormal_muscle_weight2.10476572
27MP0006138_congestive_heart_failure1.94281159
28MP0004085_abnormal_heartbeat1.94049569
29MP0003221_abnormal_cardiomyocyte_apopto1.76796235
30MP0004510_myositis1.70849042
31MP0001661_extended_life_span1.68821777
32MP0006036_abnormal_mitochondrial_physio1.65473381
33MP0003828_pulmonary_edema1.62942047
34MP0002332_abnormal_exercise_endurance1.61132553
35MP0002127_abnormal_cardiovascular_syste1.50974419
36MP0003950_abnormal_plasma_membrane1.41299939
37MP0005666_abnormal_adipose_tissue1.20047982
38MP0002108_abnormal_muscle_morphology1.16274805
39MP0002234_abnormal_pharynx_morphology1.08619445
40MP0006035_abnormal_mitochondrial_morpho1.08019530
41MP0004270_analgesia1.03312912
42MP0010030_abnormal_orbit_morphology1.00646464
43MP0004859_abnormal_synaptic_plasticity0.98578412
44MP0004185_abnormal_adipocyte_glucose0.97171594
45MP0000266_abnormal_heart_morphology0.96100189
46MP0003567_abnormal_fetal_cardiomyocyte0.92021823
47MP0000733_abnormal_muscle_development0.86789877
48MP0005670_abnormal_white_adipose0.83738713
49MP0005375_adipose_tissue_phenotype0.83107700
50MP0005165_increased_susceptibility_to0.82567706
51MP0000343_altered_response_to0.81509545
52MP0000013_abnormal_adipose_tissue0.78196106
53MP0005623_abnormal_meninges_morphology0.78183992
54MP0009672_abnormal_birth_weight0.78065705
55MP0005266_abnormal_metabolism0.77639387
56MP0003941_abnormal_skin_development0.75761566
57MP0002909_abnormal_adrenal_gland0.73514949
58MP0000230_abnormal_systemic_arterial0.72547086
59MP0004134_abnormal_chest_morphology0.68517796
60MP0002822_catalepsy0.65912701
61MP0010368_abnormal_lymphatic_system0.65810276
62MP0004043_abnormal_pH_regulation0.64265010
63MP0004924_abnormal_behavior0.62674346
64MP0005386_behavior/neurological_phenoty0.62674346
65MP0000372_irregular_coat_pigmentation0.62506629
66MP0002735_abnormal_chemical_nociception0.61398482
67MP0003635_abnormal_synaptic_transmissio0.60836507
68MP0002971_abnormal_brown_adipose0.60244832
69MP0003279_aneurysm0.59597787
70MP0000762_abnormal_tongue_morphology0.58981543
71MP0009250_abnormal_appendicular_skeleto0.57265983
72MP0002128_abnormal_blood_circulation0.57108264
73MP0008569_lethality_at_weaning0.56502729
74MP0009046_muscle_twitch0.55387735
75MP0002114_abnormal_axial_skeleton0.54396569
76MP0003880_abnormal_central_pattern0.53145956
77MP0009780_abnormal_chondrocyte_physiolo0.52980432
78MP0009384_cardiac_valve_regurgitation0.52751144
79MP0000003_abnormal_adipose_tissue0.51736169
80MP0005187_abnormal_penis_morphology0.49226816
81MP0009745_abnormal_behavioral_response0.49225910
82MP0002272_abnormal_nervous_system0.49175918
83MP0008961_abnormal_basal_metabolism0.48716756
84MP0004147_increased_porphyrin_level0.48043146
85MP0002734_abnormal_mechanical_nocicepti0.47684349
86MP0004858_abnormal_nervous_system0.45351763
87MP0001440_abnormal_grooming_behavior0.44814405
88MP0002078_abnormal_glucose_homeostasis0.44665374
89MP0004197_abnormal_fetal_growth/weight/0.44610656
90MP0009697_abnormal_copulation0.44570121
91MP0001299_abnormal_eye_distance/0.43005371
92MP0002067_abnormal_sensory_capabilities0.42854790
93MP0002896_abnormal_bone_mineralization0.42820942
94MP0002064_seizures0.42679590
95MP0003984_embryonic_growth_retardation0.40708293
96MP0005535_abnormal_body_temperature0.39855359
97MP0002088_abnormal_embryonic_growth/wei0.39133345
98MP0003705_abnormal_hypodermis_morpholog0.38448501
99MP0006276_abnormal_autonomic_nervous0.38311186
100MP0002063_abnormal_learning/memory/cond0.38175301
101MP0003385_abnormal_body_wall0.37471057
102MP0001346_abnormal_lacrimal_gland0.37416850
103MP0003123_paternal_imprinting0.37024032
104MP0001879_abnormal_lymphatic_vessel0.36983030
105MP0005275_abnormal_skin_tensile0.35714020
106MP0001529_abnormal_vocalization0.35223071
107MP0000534_abnormal_ureter_morphology0.34927761
108MP0003948_abnormal_gas_homeostasis0.34748426
109MP0001968_abnormal_touch/_nociception0.33826083
110MP0003566_abnormal_cell_adhesion0.33217417
111MP0009703_decreased_birth_body0.33200974
112MP0005452_abnormal_adipose_tissue0.33115362
113MP0002066_abnormal_motor_capabilities/c0.33008934
114MP0004142_abnormal_muscle_tone0.32069718
115MP0004272_abnormal_basement_membrane0.31640595
116MP0001970_abnormal_pain_threshold0.31354254
117MP0001672_abnormal_embryogenesis/_devel0.31323863
118MP0005380_embryogenesis_phenotype0.31323863
119MP0003045_fibrosis0.31011139
120MP0002925_abnormal_cardiovascular_devel0.30975835
121MP0001730_embryonic_growth_arrest0.30613799
122MP0000767_abnormal_smooth_muscle0.28510362
123MP0005451_abnormal_body_composition0.27824013
124MP0003329_amyloid_beta_deposits0.26827711
125MP0001984_abnormal_olfaction0.26713411
126MP0001943_abnormal_respiration0.25479645
127MP0002638_abnormal_pupillary_reflex0.24338501
128MP0003755_abnormal_palate_morphology0.24131351
129MP0005334_abnormal_fat_pad0.23887243
130MP0003942_abnormal_urinary_system0.22850593
131MP0002081_perinatal_lethality0.22650719
132MP0003937_abnormal_limbs/digits/tail_de0.22520932
133MP0005376_homeostasis/metabolism_phenot0.22276671
134MP0001697_abnormal_embryo_size0.21160605

Predicted human phenotypes

RankGene SetZ-score
1Sudden death (HP:0001699)7.11256784
2Exercise-induced myalgia (HP:0003738)7.10667455
3Calf muscle hypertrophy (HP:0008981)6.73425649
4Exercise-induced muscle cramps (HP:0003710)6.67422515
5Muscle hypertrophy of the lower extremities (HP:0008968)6.60039995
6Muscle fiber splitting (HP:0003555)5.76757967
7Ventricular tachycardia (HP:0004756)5.58086788
8Abnormality of the calf musculature (HP:0001430)5.38002812
9Hyporeflexia of lower limbs (HP:0002600)5.24703857
10Muscle fiber inclusion bodies (HP:0100299)5.10811681
11Myoglobinuria (HP:0002913)5.05578572
12Atrial fibrillation (HP:0005110)4.97309429
13Muscle fiber cytoplasmatic inclusion bodies (HP:0100303)4.94844141
14Primary atrial arrhythmia (HP:0001692)4.67636250
15Abnormality of the left ventricular outflow tract (HP:0011103)4.67518270
16Subaortic stenosis (HP:0001682)4.67518270
17EMG: myopathic abnormalities (HP:0003458)4.61297142
18Supraventricular tachycardia (HP:0004755)4.50173871
19Supraventricular arrhythmia (HP:0005115)4.40189587
20Difficulty running (HP:0009046)4.33434007
21Lipoatrophy (HP:0100578)4.30199195
22Nemaline bodies (HP:0003798)4.30123429
23Type 1 muscle fiber predominance (HP:0003803)4.25403060
24Syncope (HP:0001279)4.07193524
25Myotonia (HP:0002486)4.03973886
26Increased connective tissue (HP:0009025)4.02599547
27Bundle branch block (HP:0011710)3.94321075
28Right ventricular cardiomyopathy (HP:0011663)3.92801201
29Rhabdomyolysis (HP:0003201)3.84510310
30Prolonged QT interval (HP:0001657)3.77023020
31Asymmetric septal hypertrophy (HP:0001670)3.72410823
32Calcaneovalgus deformity (HP:0001848)3.68436521
33Dilated cardiomyopathy (HP:0001644)3.61658940
34Palpitations (HP:0001962)3.56851860
35Ventricular arrhythmia (HP:0004308)3.49207180
36Muscle stiffness (HP:0003552)3.37333710
37Deformed tarsal bones (HP:0008119)3.21246702
38Distal arthrogryposis (HP:0005684)3.20555131
39Heart block (HP:0012722)3.19270321
40Ventricular fibrillation (HP:0001663)3.19062836
41Difficulty climbing stairs (HP:0003551)3.17237907
42Increased variability in muscle fiber diameter (HP:0003557)3.04607841
43Abnormal atrioventricular conduction (HP:0005150)3.00603725
44Abnormality of skeletal muscle fiber size (HP:0012084)2.96677898
45Neck muscle weakness (HP:0000467)2.92273580
46Atrioventricular block (HP:0001678)2.90205364
47Areflexia of lower limbs (HP:0002522)2.84846790
48Malignant hyperthermia (HP:0002047)2.83367575
49Abnormal EKG (HP:0003115)2.82870271
50Rimmed vacuoles (HP:0003805)2.82129580
51Myopathic facies (HP:0002058)2.81033604
52Round ear (HP:0100830)2.75500882
53Left ventricular hypertrophy (HP:0001712)2.71865824
54Abnormal finger flexion creases (HP:0006143)2.69860167
55Abnormal mitochondria in muscle tissue (HP:0008316)2.68762255
56Acute necrotizing encephalopathy (HP:0006965)2.67135242
57Distal lower limb muscle weakness (HP:0009053)2.63808218
58Slender build (HP:0001533)2.41040147
59Limb-girdle muscle atrophy (HP:0003797)2.38921939
60Bulbar palsy (HP:0001283)2.38887083
61Spinal rigidity (HP:0003306)2.36991800
62EMG: neuropathic changes (HP:0003445)2.33704143
63Hepatic necrosis (HP:0002605)2.32213201
64Progressive macrocephaly (HP:0004481)2.26274480
65Muscular dystrophy (HP:0003560)2.26166441
66Pheochromocytoma (HP:0002666)2.23252135
67Hyperkalemia (HP:0002153)2.22121141
68Abnormality of the calcaneus (HP:0008364)2.21800158
69Acute encephalopathy (HP:0006846)2.20294413
70Abnormality of the foot musculature (HP:0001436)2.20173974
71Hepatocellular necrosis (HP:0001404)2.18296626
72Hypoplastic ischia (HP:0003175)2.16276397
73Hip contracture (HP:0003273)2.15853649
74Foot dorsiflexor weakness (HP:0009027)2.15367479
75Fetal akinesia sequence (HP:0001989)2.14988614
76Palmoplantar keratoderma (HP:0000982)2.14403298
77Weak cry (HP:0001612)2.13947045
78Distal lower limb amyotrophy (HP:0008944)2.13930688
79Mitochondrial inheritance (HP:0001427)2.13045770
80Abnormality of the shoulder girdle musculature (HP:0001435)2.12592208
81Gowers sign (HP:0003391)2.11688275
82Mildly elevated creatine phosphokinase (HP:0008180)2.09637150
83Ulnar deviation of the wrist (HP:0003049)2.06610413
84Ketoacidosis (HP:0001993)2.05897430
85Exercise intolerance (HP:0003546)2.05291337
86Scapular winging (HP:0003691)2.03969620
87Shoulder girdle muscle weakness (HP:0003547)2.03302347
88Frequent falls (HP:0002359)2.02791844
89Generalized muscle weakness (HP:0003324)2.00897541
90Neuroendocrine neoplasm (HP:0100634)1.99562577
91Increased CSF lactate (HP:0002490)1.99476322
92Waddling gait (HP:0002515)1.95495935
93Abnormality of the ischium (HP:0003174)1.95173876
94Abnormality of the musculature of the pelvis (HP:0001469)1.94891820
95Abnormality of the hip-girdle musculature (HP:0001445)1.94891820
96Increased muscle lipid content (HP:0009058)1.94806498
97Dysmetric saccades (HP:0000641)1.94555716
98Centrally nucleated skeletal muscle fibers (HP:0003687)1.92357496
99Facial diplegia (HP:0001349)1.91900251
100Fatigable weakness (HP:0003473)1.91596849
101Abnormality of the neuromuscular junction (HP:0003398)1.91596849
102Proximal amyotrophy (HP:0007126)1.91386479
103Abnormality of alanine metabolism (HP:0010916)1.91362624
104Hyperalaninemia (HP:0003348)1.91362624
105Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.91362624
106Conjunctival hamartoma (HP:0100780)1.90981808
107Aplasia/Hypoplasia of the pubic bone (HP:0009104)1.88296169
108Testicular atrophy (HP:0000029)1.87373298
109Ragged-red muscle fibers (HP:0003200)1.85759269
110Cerebral edema (HP:0002181)1.85446308
111Pelvic girdle muscle weakness (HP:0003749)1.85413991
112Central scotoma (HP:0000603)1.85225321
113Lower limb amyotrophy (HP:0007210)1.85122149
114Limb-girdle muscle weakness (HP:0003325)1.81443177
115Absent phalangeal crease (HP:0006109)1.80152613
116Increased intramyocellular lipid droplets (HP:0012240)1.79634362
117Long clavicles (HP:0000890)1.77962145
118Progressive muscle weakness (HP:0003323)1.76099847
119Respiratory insufficiency due to muscle weakness (HP:0002747)1.75301237
120Lactic acidosis (HP:0003128)1.74082386
121Hamartoma of the eye (HP:0010568)1.71671545
122Sudden cardiac death (HP:0001645)1.70986109
123Limited hip movement (HP:0008800)1.63241033
124Metatarsus adductus (HP:0001840)1.56684418
125Steppage gait (HP:0003376)1.55724600
126Popliteal pterygium (HP:0009756)1.49594930
127Oligomenorrhea (HP:0000876)1.44647906
128Ulnar deviation of finger (HP:0009465)1.42939303
129Nonprogressive disorder (HP:0003680)1.35896654
130Hypoalphalipoproteinemia (HP:0003233)1.29350430

Predicted kinase interactions (KEA)

RankGene SetZ-score
1OBSCN6.24303240
2TTN5.56773316
3PHKG24.83669465
4PHKG14.83669465
5PDK43.19522077
6PDK33.19522077
7LMTK22.96767081
8DMPK2.79222847
9MYLK2.62897842
10NEK12.54238171
11PKN22.13994104
12PINK12.12629373
13PIK3CA2.07721435
14MUSK2.07148694
15EEF2K1.97499126
16PDK21.88323286
17TRIB31.86587346
18NME11.82394136
19STK241.70074549
20BCKDK1.57581056
21MAP3K71.41015638
22TIE11.28767244
23PAK31.25289140
24GRK71.23233191
25CAMK2D1.22470276
26MAPK121.20291954
27CCNB11.18407802
28MAP2K41.14170002
29MAP3K41.02152316
30PIK3CG1.00735212
31PRKD10.98149078
32MAP2K30.97348051
33ILK0.93355032
34ROCK10.88610525
35PRKAA10.87576236
36LATS20.85151500
37ZAK0.84724589
38CDC42BPA0.82555200
39STK380.81886723
40CAMK2A0.77518510
41ERBB30.77048654
42PRKAA20.76690601
43PAK60.76635096
44LATS10.75896734
45MAPKAPK30.75877793
46WNK40.75876677
47MAP3K100.75852813
48PKN10.75769835
49STK38L0.74316742
50RPS6KB20.72485237
51NTRK30.70316643
52WNK10.70180838
53MAP3K50.68608648
54RIPK10.66871823
55MOS0.64356065
56CAMK40.61235795
57CAMK10.60288570
58CAMK2G0.59683397
59KSR20.57840167
60ROCK20.56895424
61PTK2B0.56222795
62MARK10.56067418
63TRPM70.56054070
64DAPK30.52675787
65PRKD30.52484980
66INSRR0.52457065
67PRKACB0.52445092
68DYRK1B0.50034836
69STK390.48597964
70LIMK10.48490360
71MTOR0.46412954
72MAPK110.46317390
73PRKACA0.45800436
74MAPK70.45499130
75FER0.44508587
76PRKCE0.42648826
77PDGFRA0.42626625
78PDPK10.41675039
79MAP2K60.40769122
80AKT20.40088484
81MAPK40.39907945
82RET0.39826999
83CDC70.38630030
84MINK10.38387560
85TAOK10.37027534
86PDK10.36163852
87SGK10.35877702
88MAP3K30.34742805
89RPS6KB10.33764865
90PRKACG0.33663802
91EPHA40.33550414
92PNCK0.33498411
93MAP3K90.32448799
94PRKG10.31724256
95TTK0.29870876
96MAPK100.29680587
97RPS6KA30.29376505
98PRKCH0.29308817
99SGK30.28172898
100RPS6KA10.28091156
101NEK90.27565309
102GRK50.27088534
103FLT30.27022404
104MAP2K70.26303396
105SCYL20.24813291
106MET0.24495228
107STK110.24210732
108CDK80.24209975
109TNIK0.23466369
110ICK0.23463283
111RPS6KC10.23147465
112RPS6KL10.23147465
113MAP2K10.21406958
114SGK20.20774126
115CAMK2B0.20600859
116MAP3K10.20425652
117STK40.20279449
118UHMK10.19559099
119CDK50.19550405
120NEK20.18725674
121TAF10.17953739
122MELK0.17892187
123PLK10.17401037
124EPHB10.17224913
125FGFR10.16728525
126RPS6KA20.16459011
127PRKDC0.16443844
128MAP3K60.16383078
129CDK10.16333202
130CDK40.16003574
131SIK10.15793213
132GSK3B0.15718504
133SGK4940.15716246
134SGK2230.15716246
135MAP3K130.14864847
136AURKB0.14535781
137FGFR30.14509175
138PLK40.13627255
139CDK120.13569602
140CAMK1G0.13421622
141NLK0.12293853

Predicted pathways (KEGG)

RankGene SetZ-score
1Citrate cycle (TCA cycle)_Homo sapiens_hsa000205.18456089
2Cardiac muscle contraction_Homo sapiens_hsa042604.35401253
3Dilated cardiomyopathy_Homo sapiens_hsa054143.71606930
4Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054103.67981783
52-Oxocarboxylic acid metabolism_Homo sapiens_hsa012103.63748932
6Parkinsons disease_Homo sapiens_hsa050122.98111045
7Oxidative phosphorylation_Homo sapiens_hsa001902.95992383
8Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004002.75233818
9Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054122.72750480
10Propanoate metabolism_Homo sapiens_hsa006402.50323986
11Alzheimers disease_Homo sapiens_hsa050102.34761204
12Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042612.16671603
13Carbon metabolism_Homo sapiens_hsa012002.01800554
14Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.88816650
15Fatty acid degradation_Homo sapiens_hsa000711.87009214
16Huntingtons disease_Homo sapiens_hsa050161.85062346
17Pyruvate metabolism_Homo sapiens_hsa006201.52040279
18Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.50842751
19Fatty acid metabolism_Homo sapiens_hsa012121.50100624
20Pentose phosphate pathway_Homo sapiens_hsa000301.48627397
21Oxytocin signaling pathway_Homo sapiens_hsa049211.36721598
22Viral myocarditis_Homo sapiens_hsa054161.36531532
23Calcium signaling pathway_Homo sapiens_hsa040201.34346298
24Glucagon signaling pathway_Homo sapiens_hsa049221.30854939
25cGMP-PKG signaling pathway_Homo sapiens_hsa040221.27487774
26Glycolysis / Gluconeogenesis_Homo sapiens_hsa000101.20841028
27Insulin signaling pathway_Homo sapiens_hsa049101.18051988
28Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.11288058
29Starch and sucrose metabolism_Homo sapiens_hsa005001.05286999
30Insulin resistance_Homo sapiens_hsa049311.05074336
31Circadian entrainment_Homo sapiens_hsa047131.04288627
32Butanoate metabolism_Homo sapiens_hsa006501.04113529
33Insulin secretion_Homo sapiens_hsa049110.98182900
34Gastric acid secretion_Homo sapiens_hsa049710.95070096
35Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.94749158
36Renin secretion_Homo sapiens_hsa049240.94121129
37Vascular smooth muscle contraction_Homo sapiens_hsa042700.94017776
38Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.93559036
39Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.91377788
40Adipocytokine signaling pathway_Homo sapiens_hsa049200.91229451
41Type II diabetes mellitus_Homo sapiens_hsa049300.90062397
42Biosynthesis of amino acids_Homo sapiens_hsa012300.88402115
43Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.86782630
44Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.85246600
45Fatty acid elongation_Homo sapiens_hsa000620.83233627
46Olfactory transduction_Homo sapiens_hsa047400.82799578
47AMPK signaling pathway_Homo sapiens_hsa041520.80520663
48Circadian rhythm_Homo sapiens_hsa047100.79367668
49Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.78731034
50Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.76908650
51Tight junction_Homo sapiens_hsa045300.73771294
52Aldosterone synthesis and secretion_Homo sapiens_hsa049250.72911031
53Cholinergic synapse_Homo sapiens_hsa047250.70767242
54GABAergic synapse_Homo sapiens_hsa047270.70735378
55Long-term potentiation_Homo sapiens_hsa047200.70314546
56HIF-1 signaling pathway_Homo sapiens_hsa040660.70042749
57GnRH signaling pathway_Homo sapiens_hsa049120.69227720
58Focal adhesion_Homo sapiens_hsa045100.69036152
59cAMP signaling pathway_Homo sapiens_hsa040240.68618785
60Oocyte meiosis_Homo sapiens_hsa041140.66083289
61Central carbon metabolism in cancer_Homo sapiens_hsa052300.64836127
62Morphine addiction_Homo sapiens_hsa050320.62317521
63Taste transduction_Homo sapiens_hsa047420.61404752
64Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.61385380
65Salivary secretion_Homo sapiens_hsa049700.60015367
66Galactose metabolism_Homo sapiens_hsa000520.58913918
67Dopaminergic synapse_Homo sapiens_hsa047280.55608363
68Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.54651805
69Thyroid cancer_Homo sapiens_hsa052160.54183549
70Cysteine and methionine metabolism_Homo sapiens_hsa002700.53861202
71Nitrogen metabolism_Homo sapiens_hsa009100.53627729
72Fructose and mannose metabolism_Homo sapiens_hsa000510.53609646
73Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.53379675
74Thyroid hormone signaling pathway_Homo sapiens_hsa049190.53028508
75Glutamatergic synapse_Homo sapiens_hsa047240.52545909
76Longevity regulating pathway - mammal_Homo sapiens_hsa042110.51856381
77PPAR signaling pathway_Homo sapiens_hsa033200.51718526
78Gap junction_Homo sapiens_hsa045400.50870919
79FoxO signaling pathway_Homo sapiens_hsa040680.49678767
80Nicotine addiction_Homo sapiens_hsa050330.45940768
81Arginine and proline metabolism_Homo sapiens_hsa003300.45438501
82Amphetamine addiction_Homo sapiens_hsa050310.45353970
83Arginine biosynthesis_Homo sapiens_hsa002200.43985990
84Purine metabolism_Homo sapiens_hsa002300.43655048
85Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.43403731
86RNA degradation_Homo sapiens_hsa030180.42360512
87Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.41827456
88Fatty acid biosynthesis_Homo sapiens_hsa000610.40919004
89Ovarian steroidogenesis_Homo sapiens_hsa049130.38830866
90Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.38777204
91mRNA surveillance pathway_Homo sapiens_hsa030150.38412502
92Synaptic vesicle cycle_Homo sapiens_hsa047210.38336519
93mTOR signaling pathway_Homo sapiens_hsa041500.37238702
94Hippo signaling pathway_Homo sapiens_hsa043900.36610731
95Serotonergic synapse_Homo sapiens_hsa047260.36358960
96Dorso-ventral axis formation_Homo sapiens_hsa043200.34998236
97VEGF signaling pathway_Homo sapiens_hsa043700.34936943
98MAPK signaling pathway_Homo sapiens_hsa040100.34757735
99Renal cell carcinoma_Homo sapiens_hsa052110.33995553
100Endometrial cancer_Homo sapiens_hsa052130.33127000
101beta-Alanine metabolism_Homo sapiens_hsa004100.31374111
102Melanogenesis_Homo sapiens_hsa049160.31332847
103Pancreatic secretion_Homo sapiens_hsa049720.31206086
104Wnt signaling pathway_Homo sapiens_hsa043100.30857398
105Regulation of actin cytoskeleton_Homo sapiens_hsa048100.30738100
106One carbon pool by folate_Homo sapiens_hsa006700.30473523
107Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.29879129
108Estrogen signaling pathway_Homo sapiens_hsa049150.29806237
109Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.29359601
110ECM-receptor interaction_Homo sapiens_hsa045120.29223881
111Basal cell carcinoma_Homo sapiens_hsa052170.28539162
112Glioma_Homo sapiens_hsa052140.28461919
113Tryptophan metabolism_Homo sapiens_hsa003800.28422683
114Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.28028798
115Lysine degradation_Homo sapiens_hsa003100.27604810
116Adherens junction_Homo sapiens_hsa045200.27247144
117Long-term depression_Homo sapiens_hsa047300.26921492
118Nucleotide excision repair_Homo sapiens_hsa034200.26773356
119Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.26244403
120Proteoglycans in cancer_Homo sapiens_hsa052050.25866104
121RNA transport_Homo sapiens_hsa030130.25652147
122Amoebiasis_Homo sapiens_hsa051460.24899203
123Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.23050398
124Phenylalanine metabolism_Homo sapiens_hsa003600.21790479
125Axon guidance_Homo sapiens_hsa043600.19277396
126Platelet activation_Homo sapiens_hsa046110.18989780

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