

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | epithelial structure maintenance (GO:0010669) | 8.40297212 |
| 2 | response to vitamin A (GO:0033189) | 7.80551172 |
| 3 | mesenchymal cell differentiation involved in renal system development (GO:2001012) | 7.56479517 |
| 4 | mesenchymal cell differentiation involved in kidney development (GO:0072161) | 7.56479517 |
| 5 | sperm capacitation (GO:0048240) | 6.78228958 |
| 6 | cellular response to epidermal growth factor stimulus (GO:0071364) | 6.33114291 |
| 7 | O-glycan processing (GO:0016266) | 6.19969137 |
| 8 | protein-chromophore linkage (GO:0018298) | 6.05041336 |
| 9 | histone H3-K36 demethylation (GO:0070544) | 5.77584984 |
| 10 | membrane depolarization during action potential (GO:0086010) | 5.72718136 |
| 11 | multicellular organism reproduction (GO:0032504) | 5.63590103 |
| 12 | rRNA catabolic process (GO:0016075) | 5.58601078 |
| 13 | calcium ion import (GO:0070509) | 5.47418977 |
| 14 | positive regulation of sodium ion transmembrane transporter activity (GO:2000651) | 5.25980723 |
| 15 | cGMP-mediated signaling (GO:0019934) | 5.02661614 |
| 16 | nephron tubule morphogenesis (GO:0072078) | 4.90948964 |
| 17 | nephron epithelium morphogenesis (GO:0072088) | 4.90948964 |
| 18 | regulation of platelet aggregation (GO:0090330) | 4.79393133 |
| 19 | response to epidermal growth factor (GO:0070849) | 4.73252289 |
| 20 | cellular response to glucocorticoid stimulus (GO:0071385) | 4.72806297 |
| 21 | negative regulation of homotypic cell-cell adhesion (GO:0034111) | 4.69187520 |
| 22 | relaxation of smooth muscle (GO:0044557) | 4.67790364 |
| 23 | regulation of ARF GTPase activity (GO:0032312) | 4.64254793 |
| 24 | sphingosine metabolic process (GO:0006670) | 4.52145090 |
| 25 | C21-steroid hormone biosynthetic process (GO:0006700) | 4.49328663 |
| 26 | DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 cla | 4.47469646 |
| 27 | cellular response to corticosteroid stimulus (GO:0071384) | 4.34661060 |
| 28 | phosphate ion homeostasis (GO:0055062) | 4.25459949 |
| 29 | trivalent inorganic anion homeostasis (GO:0072506) | 4.25459949 |
| 30 | protein O-linked glycosylation (GO:0006493) | 4.22359645 |
| 31 | behavioral response to nicotine (GO:0035095) | 4.20380498 |
| 32 | negative regulation of hematopoietic progenitor cell differentiation (GO:1901533) | 4.15993391 |
| 33 | membrane repolarization during cardiac muscle cell action potential (GO:0086013) | 4.14657393 |
| 34 | diol metabolic process (GO:0034311) | 4.04231813 |
| 35 | L-fucose catabolic process (GO:0042355) | 4.03505865 |
| 36 | fucose catabolic process (GO:0019317) | 4.03505865 |
| 37 | L-fucose metabolic process (GO:0042354) | 4.03505865 |
| 38 | tachykinin receptor signaling pathway (GO:0007217) | 4.02147901 |
| 39 | positive regulation of histone deacetylation (GO:0031065) | 4.01833009 |
| 40 | negative regulation of intracellular estrogen receptor signaling pathway (GO:0033147) | 3.97719458 |
| 41 | cellular anion homeostasis (GO:0030002) | 3.97494787 |
| 42 | negative regulation of digestive system process (GO:0060457) | 3.97044122 |
| 43 | regulation of RIG-I signaling pathway (GO:0039535) | 3.96419347 |
| 44 | DNA damage response, signal transduction resulting in transcription (GO:0042772) | 3.93917627 |
| 45 | regulation of acrosome reaction (GO:0060046) | 3.89211380 |
| 46 | glucocorticoid biosynthetic process (GO:0006704) | 3.76390755 |
| 47 | striated muscle atrophy (GO:0014891) | 3.75476595 |
| 48 | regulation of histone deacetylation (GO:0031063) | 3.74654085 |
| 49 | establishment of protein localization to Golgi (GO:0072600) | 3.74632338 |
| 50 | phosphatidylglycerol biosynthetic process (GO:0006655) | 3.72005821 |
| 51 | renal tubule morphogenesis (GO:0061333) | 3.67761544 |
| 52 | phosphate ion transmembrane transport (GO:0035435) | 3.66500776 |
| 53 | positive regulation of sodium ion transmembrane transport (GO:1902307) | 3.66033157 |
| 54 | membrane repolarization during action potential (GO:0086011) | 3.65937317 |
| 55 | rhodopsin mediated signaling pathway (GO:0016056) | 3.59772136 |
| 56 | protein targeting to Golgi (GO:0000042) | 3.56763462 |
| 57 | actin filament capping (GO:0051693) | 3.52105534 |
| 58 | reproduction (GO:0000003) | 3.51775473 |
| 59 | regulation of mitochondrial translation (GO:0070129) | 3.50166048 |
| 60 | skeletal muscle adaptation (GO:0043501) | 3.41865217 |
| 61 | retrograde transport, vesicle recycling within Golgi (GO:0000301) | 3.39478444 |
| 62 | ceramide catabolic process (GO:0046514) | 3.39379980 |
| 63 | digestive system process (GO:0022600) | 3.39135913 |
| 64 | motile cilium assembly (GO:0044458) | 3.36158589 |
| 65 | regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway (GO:0039531) | 3.33045038 |
| 66 | sphingoid metabolic process (GO:0046519) | 3.29181789 |
| 67 | auditory receptor cell stereocilium organization (GO:0060088) | 3.27866546 |
| 68 | phosphate ion transport (GO:0006817) | 3.25914958 |
| 69 | positive regulation by host of viral transcription (GO:0043923) | 3.23864924 |
| 70 | muscle atrophy (GO:0014889) | 3.13899501 |
| 71 | Arp2/3 complex-mediated actin nucleation (GO:0034314) | 3.13141759 |
| 72 | fucosylation (GO:0036065) | 3.12822424 |
| 73 | response to pheromone (GO:0019236) | 3.10230990 |
| 74 | positive regulation of interleukin-17 production (GO:0032740) | 3.05166588 |
| 75 | membrane depolarization during cardiac muscle cell action potential (GO:0086012) | 3.00098726 |
| 76 | mesenchymal cell differentiation (GO:0048762) | 2.94714018 |
| 77 | cardiolipin metabolic process (GO:0032048) | 2.93986086 |
| 78 | actin nucleation (GO:0045010) | 2.92975546 |
| 79 | bone trabecula formation (GO:0060346) | 2.90804047 |
| 80 | negative regulation of actin filament depolymerization (GO:0030835) | 2.88718151 |
| 81 | negative regulation of leukocyte chemotaxis (GO:0002689) | 2.87292454 |
| 82 | negative regulation of platelet activation (GO:0010544) | 2.85800977 |
| 83 | regulation of homotypic cell-cell adhesion (GO:0034110) | 2.84252040 |
| 84 | myoblast fusion (GO:0007520) | 2.80423366 |
| 85 | striated muscle adaptation (GO:0014888) | 2.76184817 |
| 86 | epithelial to mesenchymal transition involved in endocardial cushion formation (GO:0003198) | 2.76056939 |
| 87 | protein localization to Golgi apparatus (GO:0034067) | 2.75501753 |
| 88 | single fertilization (GO:0007338) | 2.74987564 |
| 89 | cardiac conduction (GO:0061337) | 2.72746607 |
| 90 | positive regulation of protein deacetylation (GO:0090312) | 2.68231665 |
| 91 | vocalization behavior (GO:0071625) | 2.68116769 |
| 92 | positive regulation of uterine smooth muscle contraction (GO:0070474) | 2.68115069 |
| 93 | renal absorption (GO:0070293) | 2.66634659 |
| 94 | cilium or flagellum-dependent cell motility (GO:0001539) | 2.66474699 |
| 95 | calcium ion transmembrane transport (GO:0070588) | 2.65989653 |
| 96 | negative regulation by host of viral transcription (GO:0043922) | 2.65258060 |
| 97 | regulation of ruffle assembly (GO:1900027) | 2.65013017 |
| 98 | regulation of gonadotropin secretion (GO:0032276) | 2.62942457 |
| 99 | regulation of G0 to G1 transition (GO:0070316) | 12.7330986 |
| 100 | maintenance of gastrointestinal epithelium (GO:0030277) | 11.5448607 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 5.04663397 |
| 2 | DROSHA_22980978_ChIP-Seq_HELA_Human | 4.31333796 |
| 3 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 4.03958007 |
| 4 | EZH2_22144423_ChIP-Seq_EOC_Human | 3.46439007 |
| 5 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 3.13383546 |
| 6 | GBX2_23144817_ChIP-Seq_PC3_Human | 2.92139409 |
| 7 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 2.19440102 |
| 8 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 2.19329900 |
| 9 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 2.08893761 |
| 10 | CDX2_20551321_ChIP-Seq_CACO-2_Human | 1.84428362 |
| 11 | CTCF_27219007_Chip-Seq_Bcells_Human | 1.78882116 |
| 12 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 1.77776672 |
| 13 | WDR5_24793694_ChIP-Seq_LNCAP_Human | 1.77242626 |
| 14 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 1.73052579 |
| 15 | EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.68843256 |
| 16 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.65162076 |
| 17 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.64851746 |
| 18 | SMC4_20622854_ChIP-Seq_HELA_Human | 1.61652253 |
| 19 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 1.57819461 |
| 20 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.55678268 |
| 21 | VDR_22108803_ChIP-Seq_LS180_Human | 1.51681074 |
| 22 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.49120226 |
| 23 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 1.47810392 |
| 24 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 1.46946062 |
| 25 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.45129947 |
| 26 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 1.43465412 |
| 27 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 1.42307715 |
| 28 | AHR_22903824_ChIP-Seq_MCF-7_Human | 1.41817906 |
| 29 | BCL6_27268052_Chip-Seq_Bcells_Human | 1.41532307 |
| 30 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.37502223 |
| 31 | E2F1_20622854_ChIP-Seq_HELA_Human | 1.36979288 |
| 32 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 1.35657592 |
| 33 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 1.35579345 |
| 34 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.34431640 |
| 35 | NFYA_21822215_ChIP-Seq_K562_Human | 1.34089877 |
| 36 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 1.33265829 |
| 37 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 1.33265829 |
| 38 | EBNA1_20929547_Chip-Seq_RAJI-cells_Human | 1.31664326 |
| 39 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 1.31219574 |
| 40 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 1.30951110 |
| 41 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 1.30821790 |
| 42 | OCT4_20526341_ChIP-Seq_ESCs_Human | 1.29135192 |
| 43 | ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 1.26410563 |
| 44 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.26086518 |
| 45 | P68_20966046_ChIP-Seq_HELA_Human | 1.25339382 |
| 46 | SA1_27219007_Chip-Seq_Bcells_Human | 1.25181978 |
| 47 | EGR1_19032775_ChIP-ChIP_M12_Human | 1.24891490 |
| 48 | CDX2_21074721_ChIP-Seq_CACO-2_Mouse | 1.23563316 |
| 49 | BCOR_27268052_Chip-Seq_Bcells_Human | 1.21906764 |
| 50 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.21381324 |
| 51 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 1.20134001 |
| 52 | CTCF_20526341_ChIP-Seq_ESCs_Human | 1.19476010 |
| 53 | AR_25329375_ChIP-Seq_VCAP_Human | 1.18739568 |
| 54 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 1.18632043 |
| 55 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 1.18011811 |
| 56 | NFYB_21822215_ChIP-Seq_K562_Human | 1.17551546 |
| 57 | TFAP2A_17053090_ChIP-ChIP_MCF-7_Human | 1.16817140 |
| 58 | ESR1_21235772_ChIP-Seq_MCF-7_Human | 1.16607139 |
| 59 | GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.16462357 |
| 60 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.15046513 |
| 61 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.14498377 |
| 62 | TCF4_23295773_ChIP-Seq_U87_Human | 1.14480591 |
| 63 | BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 1.14456391 |
| 64 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 1.13923730 |
| 65 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 1.13427884 |
| 66 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 1.13080504 |
| 67 | SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 1.12751508 |
| 68 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 1.12335022 |
| 69 | AR_20517297_ChIP-Seq_VCAP_Human | 1.11610880 |
| 70 | TBL1_22424771_ChIP-Seq_293T_Human | 1.10777865 |
| 71 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 1.08566883 |
| 72 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 1.07198828 |
| 73 | CDX2_22108803_ChIP-Seq_LS180_Human | 1.06774987 |
| 74 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 1.05663437 |
| 75 | STAT3_23295773_ChIP-Seq_U87_Human | 1.03129280 |
| 76 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.02467446 |
| 77 | SMAD2/3_21741376_ChIP-Seq_ESCs_Human | 1.00808573 |
| 78 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 1.00647360 |
| 79 | CBP_20019798_ChIP-Seq_JUKART_Human | 0.99504426 |
| 80 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 0.99504426 |
| 81 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.99235234 |
| 82 | AR_19668381_ChIP-Seq_PC3_Human | 0.99225584 |
| 83 | TCF4_18268006_ChIP-ChIP_LS174T_Human | 0.98677964 |
| 84 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 0.97923563 |
| 85 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 0.97774790 |
| 86 | KLF5_25053715_ChIP-Seq_YYC3_Human | 0.97680548 |
| 87 | RUNX2_22187159_ChIP-Seq_PCA_Human | 0.97611558 |
| 88 | GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.96748685 |
| 89 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 0.95957997 |
| 90 | RAC3_21632823_ChIP-Seq_H3396_Human | 0.95954151 |
| 91 | RUNX1_27514584_Chip-Seq_MCF-7_Human | 0.95580389 |
| 92 | IGF1R_20145208_ChIP-Seq_DFB_Human | 0.95232026 |
| 93 | SMAD3_22036565_ChIP-Seq_ESCs_Mouse | 0.95027494 |
| 94 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 0.94984381 |
| 95 | ERA_21632823_ChIP-Seq_H3396_Human | 0.94760984 |
| 96 | TP63_22573176_ChIP-Seq_HFKS_Human | 0.94016019 |
| 97 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 0.93511969 |
| 98 | REST_21632747_ChIP-Seq_MESCs_Mouse | 0.93136250 |
| 99 | EP300_21415370_ChIP-Seq_HL-1_Mouse | 0.92643933 |
| 100 | TAF2_19829295_ChIP-Seq_ESCs_Human | 0.92382978 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0002638_abnormal_pupillary_reflex | 5.95120293 |
| 2 | MP0004043_abnormal_pH_regulation | 5.30963362 |
| 3 | MP0000465_gastrointestinal_hemorrhage | 4.43371378 |
| 4 | MP0003879_abnormal_hair_cell | 4.22137024 |
| 5 | MP0000579_abnormal_nail_morphology | 3.96872189 |
| 6 | MP0002822_catalepsy | 3.60295259 |
| 7 | MP0001661_extended_life_span | 3.46655416 |
| 8 | MP0003950_abnormal_plasma_membrane | 3.37358114 |
| 9 | MP0003705_abnormal_hypodermis_morpholog | 2.68146925 |
| 10 | MP0001485_abnormal_pinna_reflex | 2.61526216 |
| 11 | MP0001664_abnormal_digestion | 2.54357574 |
| 12 | MP0009697_abnormal_copulation | 2.45668335 |
| 13 | MP0010386_abnormal_urinary_bladder | 2.43502090 |
| 14 | MP0003878_abnormal_ear_physiology | 2.39137058 |
| 15 | MP0005377_hearing/vestibular/ear_phenot | 2.39137058 |
| 16 | MP0000566_synostosis | 2.25858182 |
| 17 | MP0003866_abnormal_defecation | 2.20898825 |
| 18 | MP0005275_abnormal_skin_tensile | 2.03995522 |
| 19 | MP0001765_abnormal_ion_homeostasis | 1.88431944 |
| 20 | MP0001502_abnormal_circadian_rhythm | 1.86421571 |
| 21 | MP0004742_abnormal_vestibular_system | 1.85160921 |
| 22 | MP0001666_abnormal_nutrient_absorption | 1.79380971 |
| 23 | MP0001663_abnormal_digestive_system | 1.77693101 |
| 24 | MP0003183_abnormal_peptide_metabolism | 1.75970967 |
| 25 | MP0003195_calcinosis | 1.74018261 |
| 26 | MP0003045_fibrosis | 1.72390097 |
| 27 | MP0004145_abnormal_muscle_electrophysio | 1.71219179 |
| 28 | MP0004019_abnormal_vitamin_homeostasis | 1.66315833 |
| 29 | MP0000749_muscle_degeneration | 1.64866676 |
| 30 | MP0003646_muscle_fatigue | 1.62778187 |
| 31 | MP0005551_abnormal_eye_electrophysiolog | 1.61954731 |
| 32 | MP0004084_abnormal_cardiac_muscle | 1.60272155 |
| 33 | MP0000383_abnormal_hair_follicle | 1.59846642 |
| 34 | MP0000751_myopathy | 1.59393074 |
| 35 | MP0004036_abnormal_muscle_relaxation | 1.57800301 |
| 36 | MP0000538_abnormal_urinary_bladder | 1.57680010 |
| 37 | MP0008004_abnormal_stomach_pH | 1.57200593 |
| 38 | MP0001764_abnormal_homeostasis | 1.56257810 |
| 39 | MP0005381_digestive/alimentary_phenotyp | 1.55888574 |
| 40 | MP0001963_abnormal_hearing_physiology | 1.51456631 |
| 41 | MP0002735_abnormal_chemical_nociception | 1.48333838 |
| 42 | MP0008438_abnormal_cutaneous_collagen | 1.47040156 |
| 43 | MP0000427_abnormal_hair_cycle | 1.44726956 |
| 44 | MP0008057_abnormal_DNA_replication | 1.39504315 |
| 45 | MP0003191_abnormal_cellular_cholesterol | 1.28675288 |
| 46 | MP0005253_abnormal_eye_physiology | 1.24906980 |
| 47 | MP0001873_stomach_inflammation | 1.24657437 |
| 48 | MP0000372_irregular_coat_pigmentation | 1.18365533 |
| 49 | MP0002102_abnormal_ear_morphology | 1.15549533 |
| 50 | MP0002138_abnormal_hepatobiliary_system | 1.10566234 |
| 51 | MP0010678_abnormal_skin_adnexa | 1.09271918 |
| 52 | MP0003252_abnormal_bile_duct | 1.05885582 |
| 53 | MP0000026_abnormal_inner_ear | 1.03448983 |
| 54 | MP0004142_abnormal_muscle_tone | 1.02320071 |
| 55 | MP0000230_abnormal_systemic_arterial | 1.00887651 |
| 56 | MP0002269_muscular_atrophy | 1.00809664 |
| 57 | MP0008995_early_reproductive_senescence | 0.97356480 |
| 58 | MP0002733_abnormal_thermal_nociception | 0.95302436 |
| 59 | MP0002098_abnormal_vibrissa_morphology | 0.92208786 |
| 60 | MP0005360_urolithiasis | 0.91509318 |
| 61 | MP0009384_cardiac_valve_regurgitation | 0.85500496 |
| 62 | MP0010155_abnormal_intestine_physiology | 0.84743856 |
| 63 | MP0003091_abnormal_cell_migration | 0.84532686 |
| 64 | MP0002229_neurodegeneration | 0.84393237 |
| 65 | MP0000470_abnormal_stomach_morphology | 0.82607726 |
| 66 | MP0008872_abnormal_physiological_respon | 0.82383280 |
| 67 | MP0001243_abnormal_dermal_layer | 0.81254485 |
| 68 | MP0003172_abnormal_lysosome_physiology | 0.78583485 |
| 69 | MP0000049_abnormal_middle_ear | 0.76854922 |
| 70 | MP0005083_abnormal_biliary_tract | 0.76419087 |
| 71 | MP0002060_abnormal_skin_morphology | 0.73355173 |
| 72 | MP0000747_muscle_weakness | 0.73144908 |
| 73 | MP0003786_premature_aging | 0.71543177 |
| 74 | MP0003137_abnormal_impulse_conducting | 0.71059740 |
| 75 | MP0000647_abnormal_sebaceous_gland | 0.69229097 |
| 76 | MP0001968_abnormal_touch/_nociception | 0.68048388 |
| 77 | MP0002896_abnormal_bone_mineralization | 0.67522012 |
| 78 | MP0000371_diluted_coat_color | 0.67467117 |
| 79 | MP0009046_muscle_twitch | 0.67013205 |
| 80 | MP0001542_abnormal_bone_strength | 0.66751346 |
| 81 | MP0002752_abnormal_somatic_nervous | 0.62935098 |
| 82 | MP0004134_abnormal_chest_morphology | 0.62264188 |
| 83 | MP0003279_aneurysm | 0.61196410 |
| 84 | MP0005220_abnormal_exocrine_pancreas | 0.61174603 |
| 85 | MP0002272_abnormal_nervous_system | 0.60481695 |
| 86 | MP0004885_abnormal_endolymph | 0.58330193 |
| 87 | MP0002127_abnormal_cardiovascular_syste | 0.56270195 |
| 88 | MP0004859_abnormal_synaptic_plasticity | 0.55578508 |
| 89 | MP0009745_abnormal_behavioral_response | 0.55130932 |
| 90 | MP0001958_emphysema | 0.53231130 |
| 91 | MP0005595_abnormal_vascular_smooth | 0.51756981 |
| 92 | MP0002928_abnormal_bile_duct | 0.50191301 |
| 93 | MP0001970_abnormal_pain_threshold | 0.49879567 |
| 94 | MP0001986_abnormal_taste_sensitivity | 0.49842093 |
| 95 | MP0005508_abnormal_skeleton_morphology | 0.49455699 |
| 96 | MP0001324_abnormal_eye_pigmentation | 0.48596297 |
| 97 | MP0002249_abnormal_larynx_morphology | 0.48162402 |
| 98 | MP0002693_abnormal_pancreas_physiology | 0.46352923 |
| 99 | MP0002168_other_aberrant_phenotype | 0.45902528 |
| 100 | MP0000462_abnormal_digestive_system | 0.45787397 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Bilateral sensorineural hearing impairment (HP:0008619) | 7.77297498 |
| 2 | Abnormality of dentin (HP:0010299) | 7.52686242 |
| 3 | Asymmetry of the thorax (HP:0001555) | 5.87515357 |
| 4 | Fibular aplasia (HP:0002990) | 5.22263940 |
| 5 | Pili torti (HP:0003777) | 5.01914595 |
| 6 | Natal tooth (HP:0000695) | 4.74434349 |
| 7 | Palpebral edema (HP:0100540) | 4.68703692 |
| 8 | Decreased circulating renin level (HP:0003351) | 4.58509292 |
| 9 | Fibular hypoplasia (HP:0003038) | 4.13152862 |
| 10 | Hyperkalemia (HP:0002153) | 4.09533312 |
| 11 | Tracheomalacia (HP:0002779) | 4.05070809 |
| 12 | Congenital sensorineural hearing impairment (HP:0008527) | 3.91456280 |
| 13 | Abnormality of the dental pulp (HP:0006479) | 3.87830161 |
| 14 | Enlarged epiphyses (HP:0010580) | 3.86175218 |
| 15 | Mask-like facies (HP:0000298) | 3.70111354 |
| 16 | Thin bony cortex (HP:0002753) | 3.64504735 |
| 17 | Partial agenesis of the corpus callosum (HP:0001338) | 3.57417824 |
| 18 | Broad ribs (HP:0000885) | 3.55418669 |
| 19 | Abnormal trabecular bone morphology (HP:0100671) | 3.46744389 |
| 20 | Abnormality of chloride homeostasis (HP:0011422) | 3.43405336 |
| 21 | Abnormality of the lumbar spine (HP:0100712) | 3.43240181 |
| 22 | Bilateral microphthalmos (HP:0007633) | 3.40127095 |
| 23 | Abnormal hair laboratory examination (HP:0003328) | 3.34952116 |
| 24 | Thoracic kyphosis (HP:0002942) | 3.26401997 |
| 25 | Hyperactive renin-angiotensin system (HP:0000841) | 3.23958094 |
| 26 | Hypophosphatemic rickets (HP:0004912) | 3.22058552 |
| 27 | Aortic aneurysm (HP:0004942) | 3.10651826 |
| 28 | Abnormality of renin-angiotensin system (HP:0000847) | 3.03432328 |
| 29 | Hemorrhage of the eye (HP:0011885) | 2.99434518 |
| 30 | Distal lower limb amyotrophy (HP:0008944) | 2.99261557 |
| 31 | Delayed epiphyseal ossification (HP:0002663) | 2.93359830 |
| 32 | Tinnitus (HP:0000360) | 2.91406380 |
| 33 | Unilateral renal agenesis (HP:0000122) | 2.91167729 |
| 34 | Short nail (HP:0001799) | 2.90644987 |
| 35 | Patent foramen ovale (HP:0001655) | 2.86513492 |
| 36 | Delayed closure of the anterior fontanelle (HP:0001476) | 2.85177832 |
| 37 | Aplasia/Hypoplasia involving the sinuses (HP:0009120) | 2.84423972 |
| 38 | Aplasia/Hypoplasia of the fovea (HP:0008060) | 2.77699670 |
| 39 | Hypoplasia of the fovea (HP:0007750) | 2.77699670 |
| 40 | Widely patent fontanelles and sutures (HP:0004492) | 2.77566812 |
| 41 | Aplasia/Hypoplasia of the fibula (HP:0006492) | 2.76172084 |
| 42 | Mixed hearing impairment (HP:0000410) | 2.76039493 |
| 43 | Tibial bowing (HP:0002982) | 2.75005516 |
| 44 | Cystic liver disease (HP:0006706) | 2.74332851 |
| 45 | Duplicated collecting system (HP:0000081) | 2.73554722 |
| 46 | Anal stenosis (HP:0002025) | 2.65876460 |
| 47 | Bony spicule pigmentary retinopathy (HP:0007737) | 2.58371619 |
| 48 | Upper limb amyotrophy (HP:0009129) | 2.51141441 |
| 49 | Distal upper limb amyotrophy (HP:0007149) | 2.51141441 |
| 50 | Abnormality of the renal collecting system (HP:0004742) | 2.49954864 |
| 51 | Abnormality of the fibula (HP:0002991) | 2.48656403 |
| 52 | Attenuation of retinal blood vessels (HP:0007843) | 2.47431527 |
| 53 | Malnutrition (HP:0004395) | 2.47278854 |
| 54 | Ureteral duplication (HP:0000073) | 2.46925789 |
| 55 | Aplasia/Hypoplasia of the 1st metacarpal (HP:0010026) | 2.46583107 |
| 56 | Short 1st metacarpal (HP:0010034) | 2.46583107 |
| 57 | Thickened calvaria (HP:0002684) | 2.44626092 |
| 58 | Abnormality of the 1st metacarpal (HP:0010009) | 2.43810932 |
| 59 | Craniofacial hyperostosis (HP:0004493) | 2.41787418 |
| 60 | Aplasia/Hypoplasia of the macula (HP:0008059) | 2.41474716 |
| 61 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 2.39652854 |
| 62 | Fused cervical vertebrae (HP:0002949) | 2.34690496 |
| 63 | Advanced eruption of teeth (HP:0006288) | 2.27550923 |
| 64 | Cerebral aneurysm (HP:0004944) | 2.26763549 |
| 65 | Periorbital edema (HP:0100539) | 2.25087140 |
| 66 | Aplasia/Hypoplasia affecting the retina (HP:0008061) | 2.24372234 |
| 67 | Zonular cataract (HP:0010920) | 2.20812348 |
| 68 | Rough bone trabeculation (HP:0100670) | 2.20629461 |
| 69 | Abnormality of potassium homeostasis (HP:0011042) | 2.20001260 |
| 70 | Abnormality of the costochondral junction (HP:0000919) | 2.19565379 |
| 71 | Lower limb amyotrophy (HP:0007210) | 2.17325490 |
| 72 | Follicular hyperkeratosis (HP:0007502) | 2.14900400 |
| 73 | Facial edema (HP:0000282) | 2.12961023 |
| 74 | Congenital, generalized hypertrichosis (HP:0004540) | 2.11384243 |
| 75 | Broad face (HP:0000283) | 2.10813615 |
| 76 | Aneurysm (HP:0002617) | 2.07382167 |
| 77 | Spinal muscular atrophy (HP:0007269) | 2.06674527 |
| 78 | Abnormality of the thoracic spine (HP:0100711) | 2.06577456 |
| 79 | Abnormality of the distal phalanges of the toes (HP:0010182) | 2.04743520 |
| 80 | Short phalanx of the thumb (HP:0009660) | 2.02691061 |
| 81 | Abnormality of the fovea (HP:0000493) | 2.01599536 |
| 82 | Chromsome breakage (HP:0040012) | 2.00821177 |
| 83 | Abnormality of DNA repair (HP:0003254) | 1.96724307 |
| 84 | Fragile skin (HP:0001030) | 1.95975957 |
| 85 | Neoplasm of the heart (HP:0100544) | 1.93219835 |
| 86 | Premature skin wrinkling (HP:0100678) | 1.91390699 |
| 87 | Pendular nystagmus (HP:0012043) | 1.90260073 |
| 88 | Nuclear cataract (HP:0100018) | 1.89299192 |
| 89 | Metaphyseal irregularity (HP:0003025) | 1.87949974 |
| 90 | Keratoconus (HP:0000563) | 1.86763894 |
| 91 | Increased corneal curvature (HP:0100692) | 1.86763894 |
| 92 | Cranial hyperostosis (HP:0004437) | 1.84318082 |
| 93 | Abnormality of pyrimidine metabolism (HP:0004353) | 1.83434835 |
| 94 | Femoral bowing (HP:0002980) | 1.79408473 |
| 95 | Urethral obstruction (HP:0000796) | 1.76429577 |
| 96 | Mildly elevated creatine phosphokinase (HP:0008180) | 1.74450836 |
| 97 | Decreased central vision (HP:0007663) | 1.72847218 |
| 98 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 1.71794063 |
| 99 | Squamous cell carcinoma (HP:0002860) | 1.71040340 |
| 100 | Wide anterior fontanel (HP:0000260) | 1.70429823 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | WNK4 | 7.91501748 |
| 2 | MST1R | 7.30058536 |
| 3 | NME1 | 4.68489991 |
| 4 | WNK1 | 3.36592547 |
| 5 | PRKG2 | 3.16748727 |
| 6 | SIK2 | 2.92313872 |
| 7 | MET | 2.84474577 |
| 8 | SIK1 | 2.82964244 |
| 9 | SIK3 | 2.50890809 |
| 10 | SMG1 | 2.08934205 |
| 11 | MELK | 1.72775356 |
| 12 | VRK2 | 1.70843800 |
| 13 | MAP2K6 | 1.67108988 |
| 14 | NEK2 | 1.62972370 |
| 15 | ICK | 1.62183029 |
| 16 | MUSK | 1.56407218 |
| 17 | ZAK | 1.50988773 |
| 18 | TAF1 | 1.35010774 |
| 19 | DDR2 | 1.29292092 |
| 20 | INSRR | 1.26207391 |
| 21 | CDK12 | 1.23975485 |
| 22 | HIPK2 | 1.19877836 |
| 23 | STK39 | 1.18164208 |
| 24 | LMTK2 | 1.10452663 |
| 25 | MAP3K9 | 1.00479526 |
| 26 | MAP4K2 | 0.97112448 |
| 27 | OXSR1 | 0.95896420 |
| 28 | PRKAA1 | 0.90321311 |
| 29 | BLK | 0.89674954 |
| 30 | MAPKAPK5 | 0.84607805 |
| 31 | ERN1 | 0.83222094 |
| 32 | MARK3 | 0.82159418 |
| 33 | PASK | 0.81410298 |
| 34 | FRK | 0.78788220 |
| 35 | MARK2 | 0.78318582 |
| 36 | ERBB2 | 0.73233465 |
| 37 | PRKAA2 | 0.67089615 |
| 38 | MAP3K7 | 0.65308450 |
| 39 | TEC | 0.63582083 |
| 40 | ITK | 0.62678212 |
| 41 | TNK2 | 0.62654114 |
| 42 | MAP3K6 | 0.62521768 |
| 43 | PRKCH | 0.61828010 |
| 44 | GRK5 | 0.61302986 |
| 45 | ADRBK2 | 0.60830215 |
| 46 | ACVR1B | 0.58736963 |
| 47 | CDK9 | 0.57944415 |
| 48 | FGFR4 | 0.55950362 |
| 49 | TESK2 | 0.55896385 |
| 50 | CDK19 | 0.55261001 |
| 51 | STK11 | 0.53748398 |
| 52 | TXK | 0.46805907 |
| 53 | PRKCG | 0.45272560 |
| 54 | MAP3K13 | 0.44165413 |
| 55 | CAMKK1 | 0.42917314 |
| 56 | GRK1 | 0.42402152 |
| 57 | NUAK1 | 0.40712178 |
| 58 | NLK | 0.40113697 |
| 59 | PINK1 | 0.39244676 |
| 60 | JAK3 | 0.39220936 |
| 61 | NTRK1 | 0.39105233 |
| 62 | TIE1 | 0.37779445 |
| 63 | PHKG1 | 0.37719500 |
| 64 | PHKG2 | 0.37719500 |
| 65 | KIT | 0.37679983 |
| 66 | TRIB3 | 0.36226491 |
| 67 | LCK | 0.34065812 |
| 68 | TRPM7 | 0.32315925 |
| 69 | HCK | 0.32121908 |
| 70 | BTK | 0.31470361 |
| 71 | MAP3K11 | 0.30028261 |
| 72 | MAP2K2 | 0.28488984 |
| 73 | SYK | 0.27268718 |
| 74 | PDK1 | 0.27261162 |
| 75 | DAPK1 | 0.25733964 |
| 76 | BMPR1B | 0.25215450 |
| 77 | PKN1 | 0.24306397 |
| 78 | SGK1 | 0.23397857 |
| 79 | PRKG1 | 0.22966168 |
| 80 | IGF1R | 0.22898184 |
| 81 | PRKCQ | 0.22815798 |
| 82 | PTK2B | 0.21792339 |
| 83 | PDPK1 | 0.21725946 |
| 84 | PIK3CA | 0.21578147 |
| 85 | CHEK2 | 0.21503679 |
| 86 | PDGFRB | 0.20300772 |
| 87 | CDC42BPA | 0.20101479 |
| 88 | CDK8 | 0.17697834 |
| 89 | CAMK2B | 0.17460061 |
| 90 | FGR | 0.17442412 |
| 91 | ATR | 0.17340594 |
| 92 | NEK1 | 0.17071429 |
| 93 | PRKD2 | 0.16707745 |
| 94 | PRKCB | 0.16697152 |
| 95 | CASK | 0.15474288 |
| 96 | PRKACA | 0.15117514 |
| 97 | PRKCA | 0.14821870 |
| 98 | PAK2 | 0.14469754 |
| 99 | RET | 0.14125846 |
| 100 | MAPK11 | 0.12882380 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Salivary secretion_Homo sapiens_hsa04970 | 3.49861244 |
| 2 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 3.15109786 |
| 3 | Circadian entrainment_Homo sapiens_hsa04713 | 3.02816632 |
| 4 | Olfactory transduction_Homo sapiens_hsa04740 | 2.90702405 |
| 5 | ABC transporters_Homo sapiens_hsa02010 | 2.87493644 |
| 6 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 2.80836714 |
| 7 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 2.36927300 |
| 8 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 2.32835700 |
| 9 | Morphine addiction_Homo sapiens_hsa05032 | 2.11083376 |
| 10 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 2.02139750 |
| 11 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 2.01809612 |
| 12 | Cholinergic synapse_Homo sapiens_hsa04725 | 1.89548207 |
| 13 | Phototransduction_Homo sapiens_hsa04744 | 1.87455078 |
| 14 | GABAergic synapse_Homo sapiens_hsa04727 | 1.86463463 |
| 15 | Oocyte meiosis_Homo sapiens_hsa04114 | 1.84958663 |
| 16 | Taste transduction_Homo sapiens_hsa04742 | 1.82799858 |
| 17 | Glutamatergic synapse_Homo sapiens_hsa04724 | 1.75584309 |
| 18 | Insulin secretion_Homo sapiens_hsa04911 | 1.73640615 |
| 19 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 1.70551307 |
| 20 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 1.58061039 |
| 21 | Gastric acid secretion_Homo sapiens_hsa04971 | 1.56745032 |
| 22 | ECM-receptor interaction_Homo sapiens_hsa04512 | 1.53837540 |
| 23 | Protein digestion and absorption_Homo sapiens_hsa04974 | 1.46168439 |
| 24 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.44157025 |
| 25 | Calcium signaling pathway_Homo sapiens_hsa04020 | 1.37097438 |
| 26 | Bile secretion_Homo sapiens_hsa04976 | 1.36053741 |
| 27 | Serotonergic synapse_Homo sapiens_hsa04726 | 1.34586903 |
| 28 | Nicotine addiction_Homo sapiens_hsa05033 | 1.33683410 |
| 29 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.32787415 |
| 30 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 1.31627249 |
| 31 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 1.30930049 |
| 32 | Retinol metabolism_Homo sapiens_hsa00830 | 1.29718301 |
| 33 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 1.23702632 |
| 34 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 1.20861632 |
| 35 | Notch signaling pathway_Homo sapiens_hsa04330 | 1.20835280 |
| 36 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 1.20445137 |
| 37 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.19040801 |
| 38 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.18694880 |
| 39 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 1.13683374 |
| 40 | Platelet activation_Homo sapiens_hsa04611 | 1.12607581 |
| 41 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 1.11515217 |
| 42 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 1.09470817 |
| 43 | Renin secretion_Homo sapiens_hsa04924 | 1.08187924 |
| 44 | Pancreatic secretion_Homo sapiens_hsa04972 | 1.06864743 |
| 45 | cAMP signaling pathway_Homo sapiens_hsa04024 | 1.05827829 |
| 46 | Long-term depression_Homo sapiens_hsa04730 | 1.04763255 |
| 47 | Amoebiasis_Homo sapiens_hsa05146 | 1.04056172 |
| 48 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.01569660 |
| 49 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 1.01568133 |
| 50 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 1.01294928 |
| 51 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.96958673 |
| 52 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.91648777 |
| 53 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.89380245 |
| 54 | Amphetamine addiction_Homo sapiens_hsa05031 | 0.89254651 |
| 55 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.88362780 |
| 56 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.88221526 |
| 57 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.86608367 |
| 58 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.85163275 |
| 59 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.84501470 |
| 60 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.81099753 |
| 61 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.77644062 |
| 62 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.74680339 |
| 63 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.70472090 |
| 64 | Gap junction_Homo sapiens_hsa04540 | 0.69863091 |
| 65 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.67116211 |
| 66 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.66836167 |
| 67 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.65287601 |
| 68 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.64702512 |
| 69 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.64235659 |
| 70 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 0.63810345 |
| 71 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.62770730 |
| 72 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.61074865 |
| 73 | Mineral absorption_Homo sapiens_hsa04978 | 0.60841800 |
| 74 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.56605939 |
| 75 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.54037033 |
| 76 | Cocaine addiction_Homo sapiens_hsa05030 | 0.48985018 |
| 77 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.48843044 |
| 78 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.47056267 |
| 79 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.45853012 |
| 80 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.45309545 |
| 81 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.45158521 |
| 82 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.44972129 |
| 83 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.43681039 |
| 84 | Alcoholism_Homo sapiens_hsa05034 | 0.43575459 |
| 85 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.42527226 |
| 86 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 0.41868281 |
| 87 | Malaria_Homo sapiens_hsa05144 | 0.40236504 |
| 88 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.39326803 |
| 89 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.38906904 |
| 90 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.38902495 |
| 91 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.37362619 |
| 92 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.37295313 |
| 93 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.35531900 |
| 94 | Melanogenesis_Homo sapiens_hsa04916 | 0.33456474 |
| 95 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.32397928 |
| 96 | Pathways in cancer_Homo sapiens_hsa05200 | 0.32256041 |
| 97 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.31820727 |
| 98 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 0.31351404 |
| 99 | Long-term potentiation_Homo sapiens_hsa04720 | 0.29008963 |
| 100 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.27764214 |

