Rank | Gene Set | Z-score |
---|---|---|
1 | sperm motility (GO:0030317) | 5.13788136 |
2 | acrosome reaction (GO:0007340) | 4.57369011 |
3 | regulation of acrosome reaction (GO:0060046) | 4.54920711 |
4 | cilium or flagellum-dependent cell motility (GO:0001539) | 4.51591156 |
5 | fusion of sperm to egg plasma membrane (GO:0007342) | 4.38259559 |
6 | axonemal dynein complex assembly (GO:0070286) | 4.32417677 |
7 | regulation of female gonad development (GO:2000194) | 4.24996263 |
8 | motile cilium assembly (GO:0044458) | 4.18775436 |
9 | epithelial cilium movement (GO:0003351) | 4.17466488 |
10 | regulation of meiosis I (GO:0060631) | 4.02323897 |
11 | cardiac myofibril assembly (GO:0055003) | 4.02018603 |
12 | positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316) | 4.01905003 |
13 | negative regulation of potassium ion transmembrane transporter activity (GO:1901017) | 3.98105573 |
14 | positive regulation of calcium ion-dependent exocytosis (GO:0045956) | 3.86641271 |
15 | sarcomere organization (GO:0045214) | 3.85887095 |
16 | negative regulation of inclusion body assembly (GO:0090084) | 3.84771551 |
17 | regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (GO:0010880) | 3.84058662 |
18 | cell wall macromolecule catabolic process (GO:0016998) | 3.83555849 |
19 | cell wall macromolecule metabolic process (GO:0044036) | 3.83555849 |
20 | multicellular organism reproduction (GO:0032504) | 3.83074426 |
21 | regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion (GO | 3.80590579 |
22 | myofibril assembly (GO:0030239) | 3.79258539 |
23 | cilium movement (GO:0003341) | 3.78658910 |
24 | regulation of cilium movement (GO:0003352) | 3.78459855 |
25 | plasma membrane fusion (GO:0045026) | 3.76332688 |
26 | oocyte development (GO:0048599) | 3.75666909 |
27 | carnitine transport (GO:0015879) | 3.72012492 |
28 | amino-acid betaine transport (GO:0015838) | 3.72012492 |
29 | regulation of skeletal muscle contraction (GO:0014819) | 3.71887396 |
30 | regulation of DNA methylation (GO:0044030) | 3.70445163 |
31 | muscle filament sliding (GO:0030049) | 3.69465192 |
32 | actin-myosin filament sliding (GO:0033275) | 3.69465192 |
33 | single strand break repair (GO:0000012) | 3.68104699 |
34 | cell communication by electrical coupling involved in cardiac conduction (GO:0086064) | 3.68061006 |
35 | regulation of ventricular cardiac muscle cell membrane repolarization (GO:0060307) | 3.66211884 |
36 | cellular ketone body metabolic process (GO:0046950) | 3.65927652 |
37 | retinal cone cell development (GO:0046549) | 3.65926041 |
38 | sarcoplasmic reticulum calcium ion transport (GO:0070296) | 3.64793327 |
39 | protein K6-linked ubiquitination (GO:0085020) | 3.61980268 |
40 | regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882) | 3.60615126 |
41 | sperm capacitation (GO:0048240) | 3.60455416 |
42 | carnitine transmembrane transport (GO:1902603) | 3.59413013 |
43 | negative regulation of potassium ion transmembrane transport (GO:1901380) | 3.57559545 |
44 | meiotic cell cycle (GO:0051321) | 3.55037068 |
45 | negative regulation of hormone biosynthetic process (GO:0032353) | 3.54223796 |
46 | piRNA metabolic process (GO:0034587) | 3.53830669 |
47 | tricarboxylic acid cycle (GO:0006099) | 3.51026604 |
48 | regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway (GO:1902235 | 3.47760085 |
49 | cardiac muscle contraction (GO:0060048) | 3.46109050 |
50 | positive regulation of meiosis (GO:0045836) | 3.45630082 |
51 | DNA methylation involved in gamete generation (GO:0043046) | 3.42640897 |
52 | acrosome assembly (GO:0001675) | 3.41140300 |
53 | membrane depolarization during cardiac muscle cell action potential (GO:0086012) | 3.40064124 |
54 | regulation of actin filament-based movement (GO:1903115) | 3.39966891 |
55 | carnitine shuttle (GO:0006853) | 3.39249577 |
56 | spermatid development (GO:0007286) | 3.38657133 |
57 | organic cation transport (GO:0015695) | 3.37888394 |
58 | sperm-egg recognition (GO:0035036) | 3.33606190 |
59 | positive regulation of meiotic cell cycle (GO:0051446) | 3.29455398 |
60 | regulation of cell communication by electrical coupling (GO:0010649) | 3.29139824 |
61 | regulation of ryanodine-sensitive calcium-release channel activity (GO:0060314) | 3.27800826 |
62 | regulation of membrane repolarization (GO:0060306) | 3.24247074 |
63 | striated muscle contraction (GO:0006941) | 3.22409945 |
64 | cell communication by electrical coupling (GO:0010644) | 3.21045143 |
65 | regulation of type B pancreatic cell apoptotic process (GO:2000674) | 3.18545066 |
66 | ventricular cardiac muscle cell action potential (GO:0086005) | 3.17494058 |
67 | ketone body metabolic process (GO:1902224) | 3.16631450 |
68 | regulation of acetyl-CoA biosynthetic process from pyruvate (GO:0010510) | 3.16270921 |
69 | negative regulation of hormone metabolic process (GO:0032351) | 3.13518269 |
70 | actin-mediated cell contraction (GO:0070252) | 3.12347796 |
71 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 3.10132575 |
72 | reproduction (GO:0000003) | 3.09604813 |
73 | glycine transport (GO:0015816) | 3.09170803 |
74 | cell communication involved in cardiac conduction (GO:0086065) | 3.08221498 |
75 | regulation of acyl-CoA biosynthetic process (GO:0050812) | 3.08060965 |
76 | regulation of inclusion body assembly (GO:0090083) | 3.07131028 |
77 | Golgi to endosome transport (GO:0006895) | 3.02891570 |
78 | protein targeting to Golgi (GO:0000042) | 3.02786109 |
79 | membrane depolarization during action potential (GO:0086010) | 3.01539386 |
80 | positive regulation of histone H3-K4 methylation (GO:0051571) | 2.99890633 |
81 | aspartate family amino acid catabolic process (GO:0009068) | 2.99751322 |
82 | calcium ion-dependent exocytosis (GO:0017156) | 2.99219060 |
83 | positive regulation of gastrulation (GO:2000543) | 2.98956774 |
84 | glycogen catabolic process (GO:0005980) | 2.97809982 |
85 | quaternary ammonium group transport (GO:0015697) | 2.95463325 |
86 | cell-cell recognition (GO:0009988) | 2.95160159 |
87 | somite rostral/caudal axis specification (GO:0032525) | 2.92273421 |
88 | centriole assembly (GO:0098534) | 2.91407382 |
89 | retrograde transport, vesicle recycling within Golgi (GO:0000301) | 2.91058272 |
90 | actin filament-based movement (GO:0030048) | 2.89632919 |
91 | NADH metabolic process (GO:0006734) | 2.89215861 |
92 | binding of sperm to zona pellucida (GO:0007339) | 2.85993226 |
93 | fatty acid transmembrane transport (GO:1902001) | 2.85702083 |
94 | cellular potassium ion homeostasis (GO:0030007) | 2.85499618 |
95 | detection of calcium ion (GO:0005513) | 2.84823216 |
96 | regulation of hexokinase activity (GO:1903299) | 2.82796057 |
97 | regulation of glucokinase activity (GO:0033131) | 2.82796057 |
98 | establishment of protein localization to Golgi (GO:0072600) | 2.81642015 |
99 | negative regulation of cytosolic calcium ion concentration (GO:0051481) | 2.81411048 |
100 | regulation of calcium ion transmembrane transporter activity (GO:1901019) | 2.81106326 |
101 | regulation of calcium ion transmembrane transport (GO:1903169) | 2.81106326 |
102 | regulation of relaxation of muscle (GO:1901077) | 2.80750392 |
103 | calcium ion import (GO:0070509) | 2.79957613 |
104 | male meiosis (GO:0007140) | 2.79328932 |
105 | cardiac muscle hypertrophy (GO:0003300) | 2.77458155 |
106 | plasma membrane repair (GO:0001778) | 2.77275887 |
107 | regulation of striated muscle contraction (GO:0006942) | 2.76213581 |
108 | positive regulation of calcium ion transmembrane transporter activity (GO:1901021) | 2.76111361 |
109 | regulation of cardioblast proliferation (GO:0003264) | 2.76049691 |
110 | regulation of secondary heart field cardioblast proliferation (GO:0003266) | 2.76049691 |
111 | positive regulation of potassium ion transmembrane transporter activity (GO:1901018) | 2.75275596 |
112 | glucan catabolic process (GO:0009251) | 2.74609721 |
113 | regulation of coenzyme metabolic process (GO:0051196) | 2.74141933 |
114 | regulation of cofactor metabolic process (GO:0051193) | 2.74141933 |
115 | sodium ion export (GO:0071436) | 2.71877537 |
116 | fertilization (GO:0009566) | 2.70720899 |
117 | single fertilization (GO:0007338) | 2.70615866 |
118 | striated muscle hypertrophy (GO:0014897) | 2.70211865 |
119 | creatine metabolic process (GO:0006600) | 2.69703248 |
120 | cardiac muscle adaptation (GO:0014887) | 2.68670116 |
121 | cardiac muscle hypertrophy in response to stress (GO:0014898) | 2.68670116 |
122 | muscle hypertrophy in response to stress (GO:0003299) | 2.68670116 |
123 | potassium ion import (GO:0010107) | 2.68401692 |
124 | water-soluble vitamin biosynthetic process (GO:0042364) | 2.67426257 |
125 | adult heart development (GO:0007512) | 2.66751202 |
126 | regulation of cardiac muscle cell contraction (GO:0086004) | 2.66311943 |
127 | skeletal muscle contraction (GO:0003009) | 2.65890953 |
128 | regulation of steroid hormone biosynthetic process (GO:0090030) | 2.64650842 |
129 | cardiac muscle cell development (GO:0055013) | 2.64505506 |
130 | female gamete generation (GO:0007292) | 2.64006051 |
131 | nitric oxide mediated signal transduction (GO:0007263) | 2.63480924 |
132 | left/right pattern formation (GO:0060972) | 2.63168915 |
133 | epithelial cell fate commitment (GO:0072148) | 2.62927007 |
134 | regulation of steroid hormone secretion (GO:2000831) | 2.62694547 |
135 | centriole replication (GO:0007099) | 2.62371193 |
136 | actomyosin structure organization (GO:0031032) | 2.62318664 |
137 | relaxation of muscle (GO:0090075) | 2.62315184 |
138 | synaptonemal complex organization (GO:0070193) | 2.62072183 |
139 | neuron fate determination (GO:0048664) | 2.60976135 |
140 | chemosensory behavior (GO:0007635) | 2.59608296 |
141 | muscle contraction (GO:0006936) | 2.59183236 |
142 | cardiac muscle cell action potential (GO:0086001) | 2.59152611 |
143 | positive regulation of excitatory postsynaptic membrane potential (GO:2000463) | 2.58878176 |
144 | glycolytic process (GO:0006096) | 2.58685360 |
145 | relaxation of cardiac muscle (GO:0055119) | 2.57955835 |
146 | regulation of voltage-gated calcium channel activity (GO:1901385) | 2.57810726 |
147 | response to stimulus involved in regulation of muscle adaptation (GO:0014874) | 2.57203509 |
148 | insulin secretion (GO:0030073) | 2.56823855 |
149 | regulation of sarcomere organization (GO:0060297) | 2.55048851 |
150 | neuronal action potential propagation (GO:0019227) | 2.54103922 |
151 | cardiac muscle cell action potential involved in contraction (GO:0086002) | 2.50659958 |
152 | cardiac conduction (GO:0061337) | 2.49457608 |
153 | lysine metabolic process (GO:0006553) | 2.48203390 |
Rank | Gene Set | Z-score |
---|---|---|
1 | EZH2_22144423_ChIP-Seq_EOC_Human | 4.98724199 |
2 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 4.64350420 |
3 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 2.50087683 |
4 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 2.46412435 |
5 | GBX2_23144817_ChIP-Seq_PC3_Human | 2.27983297 |
6 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.19714420 |
7 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 2.05580175 |
8 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 2.04588952 |
9 | VDR_22108803_ChIP-Seq_LS180_Human | 1.99645370 |
10 | DROSHA_22980978_ChIP-Seq_HELA_Human | 1.83867991 |
11 | * SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 1.76590860 |
12 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 1.76233416 |
13 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 1.76195048 |
14 | EP300_21415370_ChIP-Seq_HL-1_Mouse | 1.74016034 |
15 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 1.73104122 |
16 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 1.72678731 |
17 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 1.66993414 |
18 | REST_21632747_ChIP-Seq_MESCs_Mouse | 1.66911563 |
19 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 1.58067732 |
20 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.51455837 |
21 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 1.50312870 |
22 | ESRRB_18555785_ChIP-Seq_MESCs_Mouse | 1.47947017 |
23 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 1.47218128 |
24 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 1.47218128 |
25 | * RARB_27405468_Chip-Seq_BRAIN_Mouse | 1.45574421 |
26 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.45089510 |
27 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 1.43443575 |
28 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 1.40122515 |
29 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 1.38304695 |
30 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.35675215 |
31 | * SMAD4_21799915_ChIP-Seq_A2780_Human | 1.35456263 |
32 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.35419619 |
33 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.34981364 |
34 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 1.34854164 |
35 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 1.33125958 |
36 | * EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.32833330 |
37 | HTT_18923047_ChIP-ChIP_STHdh_Human | 1.32526086 |
38 | MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse | 1.30541125 |
39 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.29963240 |
40 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 1.28814082 |
41 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 1.26949613 |
42 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.23648131 |
43 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 1.23507267 |
44 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.23375499 |
45 | * SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.21636119 |
46 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.21334684 |
47 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.21334684 |
48 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.20520034 |
49 | * PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse | 1.20372199 |
50 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.18824733 |
51 | TBX20_22080862_ChIP-Seq_HEART_Mouse | 1.18469091 |
52 | TBX20_22328084_ChIP-Seq_HEART_Mouse | 1.18469091 |
53 | RUNX2_22187159_ChIP-Seq_PCA_Human | 1.17616679 |
54 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.17132822 |
55 | * CDX2_22108803_ChIP-Seq_LS180_Human | 1.15523262 |
56 | FUS_26573619_Chip-Seq_HEK293_Human | 1.14864421 |
57 | ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 1.14476978 |
58 | LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.13260260 |
59 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.12391011 |
60 | ZNF217_24962896_ChIP-Seq_MCF-7_Human | 1.12170098 |
61 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 1.11725195 |
62 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 1.11627436 |
63 | FOXM1_26456572_ChIP-Seq_MCF-7_Human | 1.10356549 |
64 | CBP_21632823_ChIP-Seq_H3396_Human | 1.08750176 |
65 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 1.08567067 |
66 | CTCF_27219007_Chip-Seq_Bcells_Human | 1.08421012 |
67 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.06333769 |
68 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.05819195 |
69 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.05390351 |
70 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.05174842 |
71 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 1.04727009 |
72 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.04042332 |
73 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.03950121 |
74 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.01943847 |
75 | TBL1_22424771_ChIP-Seq_293T_Human | 1.01804841 |
76 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.01627703 |
77 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.01504271 |
78 | NFYB_21822215_ChIP-Seq_K562_Human | 1.00788055 |
79 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.00614030 |
80 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 0.99539135 |
81 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 0.99334367 |
82 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.99334367 |
83 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 0.98981702 |
84 | CBP_20019798_ChIP-Seq_JUKART_Human | 0.98981702 |
85 | AR_25329375_ChIP-Seq_VCAP_Human | 0.98937930 |
86 | * SMAD3_21741376_ChIP-Seq_HESCs_Human | 0.98898911 |
87 | * RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse | 0.98160116 |
88 | TCF4_22108803_ChIP-Seq_LS180_Human | 0.97902214 |
89 | TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse | 0.97833436 |
90 | KDM2B_26808549_Chip-Seq_REH_Human | 0.97743948 |
91 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.97624366 |
92 | AHR_22903824_ChIP-Seq_MCF-7_Human | 0.97539755 |
93 | * SMAD4_21741376_ChIP-Seq_EPCs_Human | 0.96653352 |
94 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 0.96181075 |
95 | PHF8_20622853_ChIP-Seq_HELA_Human | 0.96155300 |
96 | FOXO1_23066095_ChIP-Seq_LIVER_Mouse | 0.96152929 |
97 | TCF4_23295773_ChIP-Seq_U87_Human | 0.95389958 |
98 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 0.95279328 |
99 | WDR5_24793694_ChIP-Seq_LNCAP_Human | 0.95249533 |
100 | STAT3_23295773_ChIP-Seq_U87_Human | 0.94417195 |
101 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 0.94374373 |
102 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 0.93985310 |
103 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 0.93946326 |
104 | FLI1_21867929_ChIP-Seq_TH2_Mouse | 0.93592034 |
105 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 0.92897151 |
106 | HNFA_21074721_ChIP-Seq_CACO-2_Human | 0.92698630 |
107 | * FOXH1_21741376_ChIP-Seq_EPCs_Human | 0.92257888 |
108 | RCOR3_21632747_ChIP-Seq_MESCs_Mouse | 0.92090269 |
109 | SOX2_21211035_ChIP-Seq_LN229_Gbm | 0.91760266 |
110 | RBPJ_21746931_ChIP-Seq_IB4_Human | 0.91436895 |
111 | TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.91157431 |
112 | SMAD3_21741376_ChIP-Seq_ESCs_Human | 0.90822609 |
113 | PCGF4_22325352_ChIP-Seq_293T-Rex_Human | 0.90619217 |
114 | ELK4_26923725_Chip-Seq_MESODERM_Mouse | 0.90546846 |
115 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 0.89375902 |
116 | KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse | 0.88838268 |
117 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 0.88587029 |
118 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 0.87997602 |
119 | P300_19829295_ChIP-Seq_ESCs_Human | 0.87591966 |
120 | * WT1_25993318_ChIP-Seq_PODOCYTE_Human | 0.87553861 |
121 | RING1B_27294783_Chip-Seq_ESCs_Mouse | 0.86706268 |
122 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 0.86553014 |
123 | NR3C1_23031785_ChIP-Seq_PC12_Mouse | 0.85898077 |
124 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.85855513 |
125 | TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse | 0.85697445 |
126 | LXR_22158963_ChIP-Seq_LIVER_Mouse | 0.85474674 |
127 | AR_19668381_ChIP-Seq_PC3_Human | 0.85302415 |
128 | TAL1_26923725_Chip-Seq_HPCs_Mouse | 0.85192932 |
129 | STAT1_17558387_ChIP-Seq_HELA_Human | 0.84708566 |
130 | * SMAD4_21741376_ChIP-Seq_HESCs_Human | 0.84670845 |
131 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 0.84551745 |
132 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 0.84016415 |
133 | ER_23166858_ChIP-Seq_MCF-7_Human | 0.83832329 |
134 | ZNF652_21678463_ChIP-ChIP_ZR75-1_Human | 0.83748845 |
135 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 0.83211485 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0003646_muscle_fatigue | 5.19163019 |
2 | MP0005410_abnormal_fertilization | 4.68552185 |
3 | MP0002837_dystrophic_cardiac_calcinosis | 4.24827877 |
4 | MP0000751_myopathy | 3.77616629 |
5 | MP0004145_abnormal_muscle_electrophysio | 3.21593660 |
6 | MP0003718_maternal_effect | 3.20092024 |
7 | MP0000749_muscle_degeneration | 3.10990377 |
8 | MP0004036_abnormal_muscle_relaxation | 3.03092829 |
9 | MP0010234_abnormal_vibrissa_follicle | 2.95527716 |
10 | MP0004215_abnormal_myocardial_fiber | 2.91391309 |
11 | MP0004084_abnormal_cardiac_muscle | 2.80754159 |
12 | MP0004859_abnormal_synaptic_plasticity | 2.56112433 |
13 | MP0005551_abnormal_eye_electrophysiolog | 2.20897084 |
14 | MP0005670_abnormal_white_adipose | 2.16116274 |
15 | MP0003283_abnormal_digestive_organ | 2.13876728 |
16 | MP0005330_cardiomyopathy | 2.04745110 |
17 | MP0005620_abnormal_muscle_contractility | 2.03237631 |
18 | MP0004087_abnormal_muscle_fiber | 1.95345801 |
19 | MP0002822_catalepsy | 1.92966492 |
20 | MP0004270_analgesia | 1.92676390 |
21 | MP0004233_abnormal_muscle_weight | 1.89982271 |
22 | MP0003950_abnormal_plasma_membrane | 1.87180548 |
23 | MP0003880_abnormal_central_pattern | 1.86591108 |
24 | MP0004130_abnormal_muscle_cell | 1.85537307 |
25 | MP0002106_abnormal_muscle_physiology | 1.83445028 |
26 | MP0002269_muscular_atrophy | 1.83165204 |
27 | MP0009046_muscle_twitch | 1.77044630 |
28 | MP0003698_abnormal_male_reproductive | 1.75023127 |
29 | MP0002972_abnormal_cardiac_muscle | 1.73052543 |
30 | MP0003635_abnormal_synaptic_transmissio | 1.72544852 |
31 | MP0003137_abnormal_impulse_conducting | 1.72158326 |
32 | MP0004484_altered_response_of | 1.71638922 |
33 | MP0004043_abnormal_pH_regulation | 1.64471043 |
34 | MP0000747_muscle_weakness | 1.63085924 |
35 | MP0000013_abnormal_adipose_tissue | 1.60859899 |
36 | MP0006292_abnormal_olfactory_placode | 1.59258706 |
37 | MP0009745_abnormal_behavioral_response | 1.57229456 |
38 | MP0005379_endocrine/exocrine_gland_phen | 1.52851536 |
39 | MP0004085_abnormal_heartbeat | 1.49868951 |
40 | MP0005369_muscle_phenotype | 1.49462047 |
41 | MP0000750_abnormal_muscle_regeneration | 1.48461128 |
42 | MP0005360_urolithiasis | 1.41403476 |
43 | MP0005395_other_phenotype | 1.41096216 |
44 | MP0002064_seizures | 1.40423666 |
45 | MP0000759_abnormal_skeletal_muscle | 1.40136446 |
46 | MP0002638_abnormal_pupillary_reflex | 1.39511163 |
47 | MP0003011_delayed_dark_adaptation | 1.38520677 |
48 | MP0005645_abnormal_hypothalamus_physiol | 1.38443910 |
49 | MP0001944_abnormal_pancreas_morphology | 1.37463320 |
50 | MP0001929_abnormal_gametogenesis | 1.36443634 |
51 | MP0002272_abnormal_nervous_system | 1.36233108 |
52 | MP0003329_amyloid_beta_deposits | 1.35747206 |
53 | MP0005666_abnormal_adipose_tissue | 1.34697085 |
54 | MP0002063_abnormal_learning/memory/cond | 1.34290924 |
55 | MP0006138_congestive_heart_failure | 1.33448204 |
56 | MP0008789_abnormal_olfactory_epithelium | 1.31046414 |
57 | MP0005451_abnormal_body_composition | 1.30425738 |
58 | MP0001765_abnormal_ion_homeostasis | 1.26601549 |
59 | MP0006072_abnormal_retinal_apoptosis | 1.23838090 |
60 | MP0006036_abnormal_mitochondrial_physio | 1.23685011 |
61 | MP0008775_abnormal_heart_ventricle | 1.23522358 |
62 | MP0002163_abnormal_gland_morphology | 1.20914336 |
63 | MP0001486_abnormal_startle_reflex | 1.20641658 |
64 | MP0002572_abnormal_emotion/affect_behav | 1.19213244 |
65 | MP0001544_abnormal_cardiovascular_syste | 1.17676088 |
66 | MP0005385_cardiovascular_system_phenoty | 1.17676088 |
67 | MP0008875_abnormal_xenobiotic_pharmacok | 1.16359319 |
68 | MP0001440_abnormal_grooming_behavior | 1.13330653 |
69 | MP0003787_abnormal_imprinting | 1.09632387 |
70 | MP0005253_abnormal_eye_physiology | 1.09615582 |
71 | MP0001984_abnormal_olfaction | 1.08536230 |
72 | MP0000003_abnormal_adipose_tissue | 1.08466646 |
73 | MP0002332_abnormal_exercise_endurance | 1.07527552 |
74 | MP0010630_abnormal_cardiac_muscle | 1.07262367 |
75 | MP0001502_abnormal_circadian_rhythm | 1.06938910 |
76 | MP0005423_abnormal_somatic_nervous | 1.05257236 |
77 | MP0002067_abnormal_sensory_capabilities | 1.02637160 |
78 | MP0008569_lethality_at_weaning | 1.02512831 |
79 | MP0001968_abnormal_touch/_nociception | 1.01892758 |
80 | MP0001501_abnormal_sleep_pattern | 1.01812901 |
81 | MP0002078_abnormal_glucose_homeostasis | 1.00310116 |
82 | MP0002653_abnormal_ependyma_morphology | 0.99349718 |
83 | MP0002876_abnormal_thyroid_physiology | 0.97714919 |
84 | MP0000631_abnormal_neuroendocrine_gland | 0.96189527 |
85 | MP0002229_neurodegeneration | 0.95904409 |
86 | MP0002693_abnormal_pancreas_physiology | 0.94961366 |
87 | MP0003879_abnormal_hair_cell | 0.94262191 |
88 | MP0002736_abnormal_nociception_after | 0.94137067 |
89 | MP0002161_abnormal_fertility/fecundity | 0.93071510 |
90 | MP0002210_abnormal_sex_determination | 0.92365752 |
91 | MP0002234_abnormal_pharynx_morphology | 0.92080070 |
92 | MP0003878_abnormal_ear_physiology | 0.91520553 |
93 | MP0005377_hearing/vestibular/ear_phenot | 0.91520553 |
94 | MP0005085_abnormal_gallbladder_physiolo | 0.91383653 |
95 | MP0002734_abnormal_mechanical_nocicepti | 0.91243033 |
96 | MP0009840_abnormal_foam_cell | 0.91201413 |
97 | MP0004885_abnormal_endolymph | 0.90747777 |
98 | MP0005332_abnormal_amino_acid | 0.90444343 |
99 | MP0003122_maternal_imprinting | 0.89903050 |
100 | MP0002127_abnormal_cardiovascular_syste | 0.89396045 |
101 | MP0002160_abnormal_reproductive_system | 0.89195595 |
102 | MP0002971_abnormal_brown_adipose | 0.89182569 |
103 | MP0002090_abnormal_vision | 0.88667253 |
104 | MP0005394_taste/olfaction_phenotype | 0.88417848 |
105 | MP0005499_abnormal_olfactory_system | 0.88417848 |
106 | MP0008877_abnormal_DNA_methylation | 0.88083816 |
107 | MP0002138_abnormal_hepatobiliary_system | 0.86856671 |
108 | MP0003121_genomic_imprinting | 0.86639677 |
109 | MP0008961_abnormal_basal_metabolism | 0.86606990 |
110 | MP0006276_abnormal_autonomic_nervous | 0.86335696 |
111 | MP0001986_abnormal_taste_sensitivity | 0.84288190 |
112 | MP0005535_abnormal_body_temperature | 0.84247468 |
113 | MP0010678_abnormal_skin_adnexa | 0.84139604 |
114 | MP0000230_abnormal_systemic_arterial | 0.83891699 |
115 | MP0005386_behavior/neurological_phenoty | 0.83034059 |
116 | MP0004924_abnormal_behavior | 0.83034059 |
117 | MP0004510_myositis | 0.82971866 |
118 | MP0010329_abnormal_lipoprotein_level | 0.81337519 |
119 | MP0005266_abnormal_metabolism | 0.81182001 |
120 | MP0000653_abnormal_sex_gland | 0.81094547 |
121 | MP0005646_abnormal_pituitary_gland | 0.80101866 |
122 | MP0003890_abnormal_embryonic-extraembry | 0.79400270 |
123 | MP0002139_abnormal_hepatobiliary_system | 0.76642693 |
124 | MP0004019_abnormal_vitamin_homeostasis | 0.76338119 |
125 | MP0006035_abnormal_mitochondrial_morpho | 0.76329313 |
126 | MP0003195_calcinosis | 0.75399300 |
127 | MP0002909_abnormal_adrenal_gland | 0.74407949 |
128 | MP0003633_abnormal_nervous_system | 0.73606687 |
129 | MP0009780_abnormal_chondrocyte_physiolo | 0.73593697 |
130 | MP0005375_adipose_tissue_phenotype | 0.73294897 |
131 | MP0005623_abnormal_meninges_morphology | 0.71235616 |
132 | MP0002108_abnormal_muscle_morphology | 0.69933011 |
133 | MP0002066_abnormal_motor_capabilities/c | 0.68220204 |
134 | MP0004185_abnormal_adipocyte_glucose | 0.67718325 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Absent/shortened dynein arms (HP:0200106) | 5.89260301 |
2 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 5.89260301 |
3 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 5.88230015 |
4 | Exercise-induced myalgia (HP:0003738) | 5.76330895 |
5 | Sudden death (HP:0001699) | 4.79479678 |
6 | Calf muscle hypertrophy (HP:0008981) | 4.78725732 |
7 | Muscle hypertrophy of the lower extremities (HP:0008968) | 4.77298875 |
8 | Exercise-induced muscle cramps (HP:0003710) | 4.56608979 |
9 | Abnormal respiratory motile cilium physiology (HP:0012261) | 4.35549326 |
10 | Myoglobinuria (HP:0002913) | 3.87582076 |
11 | Abnormality of the calf musculature (HP:0001430) | 3.86347831 |
12 | Abnormal respiratory epithelium morphology (HP:0012253) | 3.86336871 |
13 | Abnormal respiratory motile cilium morphology (HP:0005938) | 3.86336871 |
14 | Muscle fiber splitting (HP:0003555) | 3.74448429 |
15 | Hyporeflexia of lower limbs (HP:0002600) | 3.69513861 |
16 | Atrial fibrillation (HP:0005110) | 3.62932954 |
17 | Abnormal ciliary motility (HP:0012262) | 3.54207516 |
18 | Bundle branch block (HP:0011710) | 3.50082496 |
19 | Ventricular tachycardia (HP:0004756) | 3.47421322 |
20 | Hypoglycemic coma (HP:0001325) | 3.45442262 |
21 | Congenital stationary night blindness (HP:0007642) | 3.44000874 |
22 | Syncope (HP:0001279) | 3.40904214 |
23 | Primary atrial arrhythmia (HP:0001692) | 3.36442718 |
24 | Rhinitis (HP:0012384) | 3.27659443 |
25 | Supraventricular tachycardia (HP:0004755) | 3.16211616 |
26 | Infertility (HP:0000789) | 3.13495875 |
27 | Supraventricular arrhythmia (HP:0005115) | 3.05859002 |
28 | Difficulty running (HP:0009046) | 3.00167020 |
29 | Focal motor seizures (HP:0011153) | 2.98505508 |
30 | Insulin-resistant diabetes mellitus (HP:0000831) | 2.98376167 |
31 | Chronic bronchitis (HP:0004469) | 2.95004892 |
32 | Distal arthrogryposis (HP:0005684) | 2.88895738 |
33 | Asymmetric septal hypertrophy (HP:0001670) | 2.84050878 |
34 | Prolonged QT interval (HP:0001657) | 2.83624705 |
35 | EMG: myopathic abnormalities (HP:0003458) | 2.83030549 |
36 | Central scotoma (HP:0000603) | 2.82346251 |
37 | Muscle fiber inclusion bodies (HP:0100299) | 2.80643831 |
38 | Male infertility (HP:0003251) | 2.78669115 |
39 | Rhabdomyolysis (HP:0003201) | 2.77925521 |
40 | Ventricular fibrillation (HP:0001663) | 2.77309498 |
41 | Heart block (HP:0012722) | 2.74945246 |
42 | Fetal akinesia sequence (HP:0001989) | 2.70553677 |
43 | Late onset (HP:0003584) | 2.69899543 |
44 | Right ventricular cardiomyopathy (HP:0011663) | 2.69232616 |
45 | Muscle fiber cytoplasmatic inclusion bodies (HP:0100303) | 2.67220416 |
46 | Hyperinsulinemic hypoglycemia (HP:0000825) | 2.65875616 |
47 | Hyperglycemia (HP:0003074) | 2.64392455 |
48 | Ventricular arrhythmia (HP:0004308) | 2.61663680 |
49 | Lipoatrophy (HP:0100578) | 2.59542919 |
50 | Aplasia/Hypoplasia of the fovea (HP:0008060) | 2.58800695 |
51 | Hypoplasia of the fovea (HP:0007750) | 2.58800695 |
52 | Abnormality of the left ventricular outflow tract (HP:0011103) | 2.58294457 |
53 | Subaortic stenosis (HP:0001682) | 2.58294457 |
54 | Abnormal atrioventricular conduction (HP:0005150) | 2.55140885 |
55 | Elevated circulating parathyroid hormone (PTH) level (HP:0003165) | 2.52545618 |
56 | Hypoglycemic seizures (HP:0002173) | 2.44647395 |
57 | Left ventricular hypertrophy (HP:0001712) | 2.43756638 |
58 | Myopathic facies (HP:0002058) | 2.41186757 |
59 | Muscle stiffness (HP:0003552) | 2.35719793 |
60 | Dysmetric saccades (HP:0000641) | 2.35468205 |
61 | Popliteal pterygium (HP:0009756) | 2.33198231 |
62 | Myotonia (HP:0002486) | 2.32335173 |
63 | Type 1 muscle fiber predominance (HP:0003803) | 2.31690953 |
64 | Abnormal gallbladder physiology (HP:0012438) | 2.31224938 |
65 | Cholecystitis (HP:0001082) | 2.31224938 |
66 | Dilated cardiomyopathy (HP:0001644) | 2.29694771 |
67 | Nemaline bodies (HP:0003798) | 2.28721086 |
68 | Ketoacidosis (HP:0001993) | 2.26389118 |
69 | Atrioventricular block (HP:0001678) | 2.25292537 |
70 | Epileptic encephalopathy (HP:0200134) | 2.23146137 |
71 | Hyperventilation (HP:0002883) | 2.21842176 |
72 | Round ear (HP:0100830) | 2.21603867 |
73 | Abnormal EKG (HP:0003115) | 2.21582327 |
74 | Difficulty climbing stairs (HP:0003551) | 2.20919303 |
75 | Hyperkalemia (HP:0002153) | 2.20632049 |
76 | Palpitations (HP:0001962) | 2.19074273 |
77 | Ketosis (HP:0001946) | 2.18782423 |
78 | Rimmed vacuoles (HP:0003805) | 2.17688696 |
79 | Abnormality of the fovea (HP:0000493) | 2.17392611 |
80 | Anterior segment dysgenesis (HP:0007700) | 2.15410178 |
81 | Dyschromatopsia (HP:0007641) | 2.12819265 |
82 | Ulnar deviation of the wrist (HP:0003049) | 2.10181790 |
83 | Increased connective tissue (HP:0009025) | 2.09535021 |
84 | Generalized aminoaciduria (HP:0002909) | 2.08115717 |
85 | Abnormality of macular pigmentation (HP:0008002) | 2.07417156 |
86 | Abnormality of the pancreatic islet cells (HP:0006476) | 2.06140425 |
87 | Abnormality of endocrine pancreas physiology (HP:0012093) | 2.06140425 |
88 | Malignant hyperthermia (HP:0002047) | 2.05288277 |
89 | Hyperphosphatemia (HP:0002905) | 2.04493547 |
90 | Gout (HP:0001997) | 2.04162691 |
91 | Abnormality of aromatic amino acid family metabolism (HP:0004338) | 1.99841829 |
92 | Azoospermia (HP:0000027) | 1.97590653 |
93 | Decreased central vision (HP:0007663) | 1.97068647 |
94 | Tubulointerstitial nephritis (HP:0001970) | 1.96726699 |
95 | Dysdiadochokinesis (HP:0002075) | 1.96538876 |
96 | Increased variability in muscle fiber diameter (HP:0003557) | 1.95103836 |
97 | Abdominal situs inversus (HP:0003363) | 1.94905986 |
98 | Abnormality of abdominal situs (HP:0011620) | 1.94905986 |
99 | Scotoma (HP:0000575) | 1.94539105 |
100 | Abnormal drinking behavior (HP:0030082) | 1.93184200 |
101 | Polydipsia (HP:0001959) | 1.93184200 |
102 | Bony spicule pigmentary retinopathy (HP:0007737) | 1.93182468 |
103 | Distal lower limb muscle weakness (HP:0009053) | 1.92925941 |
104 | Optic disc pallor (HP:0000543) | 1.92283923 |
105 | Gowers sign (HP:0003391) | 1.90751962 |
106 | Large for gestational age (HP:0001520) | 1.90286611 |
107 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 1.89912352 |
108 | Nonprogressive disorder (HP:0003680) | 1.87555670 |
109 | Congenital malformation of the right heart (HP:0011723) | 1.86751242 |
110 | Double outlet right ventricle (HP:0001719) | 1.86751242 |
111 | Centrally nucleated skeletal muscle fibers (HP:0003687) | 1.86504563 |
112 | Congenital sensorineural hearing impairment (HP:0008527) | 1.86168973 |
113 | Hip contracture (HP:0003273) | 1.86059235 |
114 | Enlarged penis (HP:0000040) | 1.85349787 |
115 | Supernumerary spleens (HP:0009799) | 1.83388418 |
116 | Frequent falls (HP:0002359) | 1.82745543 |
117 | EMG: neuropathic changes (HP:0003445) | 1.82217007 |
118 | Abnormal urine output (HP:0012590) | 1.82118847 |
119 | Absent phalangeal crease (HP:0006109) | 1.82022113 |
120 | Abnormal mitochondria in muscle tissue (HP:0008316) | 1.81495259 |
121 | Glycosuria (HP:0003076) | 1.80746841 |
122 | Abnormality of urine glucose concentration (HP:0011016) | 1.80746841 |
123 | Generalized muscle weakness (HP:0003324) | 1.80220706 |
124 | Increased circulating renin level (HP:0000848) | 1.78322734 |
125 | Myokymia (HP:0002411) | 1.78308143 |
126 | Increased purine levels (HP:0004368) | 1.77125390 |
127 | Hyperuricemia (HP:0002149) | 1.77125390 |
128 | Acute encephalopathy (HP:0006846) | 1.76513840 |
129 | Neck muscle weakness (HP:0000467) | 1.75870801 |
130 | Pigmentary retinal degeneration (HP:0001146) | 1.75357367 |
131 | Proximal tubulopathy (HP:0000114) | 1.75311591 |
132 | Maternal diabetes (HP:0009800) | 1.75170766 |
133 | Acute necrotizing encephalopathy (HP:0006965) | 1.75033999 |
134 | Focal seizures (HP:0007359) | 1.74876287 |
135 | Abnormality of renal excretion (HP:0011036) | 1.74707653 |
136 | Hyperglycinuria (HP:0003108) | 1.74473265 |
137 | Metabolic alkalosis (HP:0200114) | 1.73224985 |
138 | Choroideremia (HP:0001139) | 1.73010318 |
139 | Gaze-evoked nystagmus (HP:0000640) | 1.71822186 |
140 | Hepatic necrosis (HP:0002605) | 1.71775420 |
141 | Truncal obesity (HP:0001956) | 1.71715054 |
142 | Abnormality of skeletal muscle fiber size (HP:0012084) | 1.71576683 |
143 | Hypophosphatemic rickets (HP:0004912) | 1.71370600 |
144 | Polyuria (HP:0000103) | 1.70596534 |
145 | Medial flaring of the eyebrow (HP:0010747) | 1.70016654 |
146 | Aplasia of the musculature (HP:0100854) | 1.68164355 |
147 | Abnormality of potassium homeostasis (HP:0011042) | 1.68046390 |
Rank | Gene Set | Z-score |
---|---|---|
1 | PDK3 | 4.68704085 |
2 | PDK4 | 4.68704085 |
3 | BMPR1B | 4.33347673 |
4 | PRKD3 | 3.33777329 |
5 | FRK | 3.28813092 |
6 | PDK2 | 3.25612964 |
7 | OBSCN | 3.14123041 |
8 | MUSK | 3.09246948 |
9 | EPHA4 | 2.74794402 |
10 | PHKG2 | 2.52037687 |
11 | PHKG1 | 2.52037687 |
12 | WNK4 | 2.48247746 |
13 | PINK1 | 2.35195750 |
14 | LMTK2 | 2.27285943 |
15 | TTN | 2.24000615 |
16 | ICK | 2.09068482 |
17 | STK38 | 2.01292558 |
18 | STK39 | 1.92923466 |
19 | PTK2B | 1.68002977 |
20 | NTRK3 | 1.67285199 |
21 | TRPM7 | 1.59391962 |
22 | DMPK | 1.53293309 |
23 | MAP3K4 | 1.51830467 |
24 | PNCK | 1.51529168 |
25 | FGFR2 | 1.46886703 |
26 | PIK3CA | 1.42435346 |
27 | PLK2 | 1.38558624 |
28 | MST4 | 1.38463455 |
29 | MAP3K9 | 1.35026759 |
30 | OXSR1 | 1.32914887 |
31 | MYLK | 1.30354083 |
32 | CASK | 1.23125656 |
33 | TNIK | 1.22797837 |
34 | NME1 | 1.22634766 |
35 | MAP2K4 | 1.22246332 |
36 | TESK1 | 1.19049103 |
37 | STK38L | 1.14374747 |
38 | MAP4K2 | 1.11885851 |
39 | PAK6 | 1.10934245 |
40 | MAPK12 | 1.10474774 |
41 | BCKDK | 1.08592856 |
42 | MAP2K7 | 1.08375881 |
43 | RIPK4 | 1.08156405 |
44 | MAP3K7 | 1.07944659 |
45 | PASK | 1.07255314 |
46 | MAPK13 | 1.06444799 |
47 | TAOK3 | 1.05057010 |
48 | NEK1 | 1.02079296 |
49 | WNK1 | 0.99160881 |
50 | KSR2 | 0.96606646 |
51 | CAMK2A | 0.95184138 |
52 | PDK1 | 0.93861104 |
53 | PDPK1 | 0.89168395 |
54 | BMPR2 | 0.88932642 |
55 | CAMK2D | 0.87774784 |
56 | TAOK1 | 0.87074810 |
57 | STK3 | 0.82322968 |
58 | IRAK1 | 0.81813410 |
59 | PRKAA1 | 0.80413371 |
60 | NTRK2 | 0.80305839 |
61 | TRIM28 | 0.79941067 |
62 | FGFR3 | 0.79793078 |
63 | PRKCI | 0.79324745 |
64 | GRK1 | 0.78640189 |
65 | SGK223 | 0.78363817 |
66 | SGK494 | 0.78363817 |
67 | MAPK15 | 0.77295061 |
68 | DAPK2 | 0.77226846 |
69 | WNK3 | 0.76291025 |
70 | PRKAA2 | 0.76177970 |
71 | CAMK1 | 0.74494455 |
72 | MARK1 | 0.73245824 |
73 | ACVR1B | 0.72519897 |
74 | CAMK1G | 0.72052722 |
75 | CAMKK1 | 0.71467743 |
76 | EIF2AK3 | 0.71361271 |
77 | MAP3K6 | 0.70415112 |
78 | PRPF4B | 0.68776442 |
79 | SGK2 | 0.67353556 |
80 | CAMKK2 | 0.65866624 |
81 | MAP3K2 | 0.65667733 |
82 | GRK7 | 0.63630136 |
83 | PKN1 | 0.63447551 |
84 | STK11 | 0.61233604 |
85 | PRKCG | 0.58968447 |
86 | MOS | 0.58482435 |
87 | CDK9 | 0.56735447 |
88 | SGK3 | 0.56593509 |
89 | AKT2 | 0.55484890 |
90 | CAMK2G | 0.55186479 |
91 | ARAF | 0.54609554 |
92 | CDK3 | 0.54563076 |
93 | PLK4 | 0.54438018 |
94 | MAPKAPK3 | 0.54275686 |
95 | MAPK7 | 0.54120546 |
96 | KSR1 | 0.53999595 |
97 | INSRR | 0.53679436 |
98 | TTK | 0.52610167 |
99 | CCNB1 | 0.51833497 |
100 | SGK1 | 0.50995004 |
101 | PAK3 | 0.50683637 |
102 | BRAF | 0.50539879 |
103 | FER | 0.50467152 |
104 | ERBB3 | 0.50211669 |
105 | MARK2 | 0.50203374 |
106 | MINK1 | 0.48144771 |
107 | CDK5 | 0.47926017 |
108 | PRKD2 | 0.47385025 |
109 | MAP3K13 | 0.46607128 |
110 | PRKACA | 0.45539823 |
111 | MET | 0.45320374 |
112 | RAF1 | 0.45233933 |
113 | ROCK1 | 0.43387492 |
114 | CSNK1D | 0.43272516 |
115 | CAMK4 | 0.42532470 |
116 | GRK5 | 0.42478727 |
117 | MAP2K1 | 0.40700686 |
118 | PRKD1 | 0.40538668 |
119 | TYRO3 | 0.39978971 |
120 | MAP3K1 | 0.39835135 |
121 | MAP2K6 | 0.39675651 |
122 | STK24 | 0.37694535 |
123 | AKT3 | 0.37179834 |
124 | CSNK1G1 | 0.37149853 |
125 | PRKCE | 0.37050684 |
126 | CAMK2B | 0.36316333 |
127 | RPS6KA3 | 0.35790217 |
128 | MAP3K5 | 0.35373651 |
129 | PRKCZ | 0.34781727 |
130 | PRKG1 | 0.34762842 |
131 | CDC42BPA | 0.34428734 |
132 | AURKA | 0.33963596 |
133 | NEK6 | 0.33664412 |
134 | PRKACB | 0.33238210 |
135 | NLK | 0.32585151 |
136 | MAPK10 | 0.32578726 |
137 | PIK3CG | 0.32294186 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 4.43215549 |
2 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 2.84033803 |
3 | Phototransduction_Homo sapiens_hsa04744 | 2.68389519 |
4 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 2.60534853 |
5 | Propanoate metabolism_Homo sapiens_hsa00640 | 2.55966200 |
6 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 2.27051386 |
7 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 2.02140483 |
8 | Fatty acid degradation_Homo sapiens_hsa00071 | 1.95046180 |
9 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.90781530 |
10 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 1.90083116 |
11 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 1.77748294 |
12 | Nicotine addiction_Homo sapiens_hsa05033 | 1.77000742 |
13 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 1.71813517 |
14 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 1.67265897 |
15 | Fatty acid metabolism_Homo sapiens_hsa01212 | 1.58114517 |
16 | Circadian entrainment_Homo sapiens_hsa04713 | 1.53934945 |
17 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 1.51355107 |
18 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 1.50749225 |
19 | Carbon metabolism_Homo sapiens_hsa01200 | 1.45130489 |
20 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.39784430 |
21 | Salivary secretion_Homo sapiens_hsa04970 | 1.38139022 |
22 | Glutamatergic synapse_Homo sapiens_hsa04724 | 1.36602218 |
23 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 1.36048904 |
24 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 1.34937105 |
25 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.34835940 |
26 | Amphetamine addiction_Homo sapiens_hsa05031 | 1.34660883 |
27 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 1.34610634 |
28 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 1.34409433 |
29 | Calcium signaling pathway_Homo sapiens_hsa04020 | 1.33369661 |
30 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 1.32098027 |
31 | Basal transcription factors_Homo sapiens_hsa03022 | 1.31639374 |
32 | Olfactory transduction_Homo sapiens_hsa04740 | 1.31521907 |
33 | Renin secretion_Homo sapiens_hsa04924 | 1.31379928 |
34 | PPAR signaling pathway_Homo sapiens_hsa03320 | 1.31192578 |
35 | Oocyte meiosis_Homo sapiens_hsa04114 | 1.30793220 |
36 | Circadian rhythm_Homo sapiens_hsa04710 | 1.29422295 |
37 | Long-term potentiation_Homo sapiens_hsa04720 | 1.29089354 |
38 | Insulin secretion_Homo sapiens_hsa04911 | 1.28459483 |
39 | GABAergic synapse_Homo sapiens_hsa04727 | 1.28177737 |
40 | Gastric acid secretion_Homo sapiens_hsa04971 | 1.27271088 |
41 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.26081955 |
42 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 1.25903702 |
43 | Alzheimers disease_Homo sapiens_hsa05010 | 1.24307250 |
44 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 1.22797263 |
45 | Parkinsons disease_Homo sapiens_hsa05012 | 1.22083338 |
46 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.20547459 |
47 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 1.20117736 |
48 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 1.19061393 |
49 | Morphine addiction_Homo sapiens_hsa05032 | 1.16534613 |
50 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 1.16526107 |
51 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.14616803 |
52 | Arginine biosynthesis_Homo sapiens_hsa00220 | 1.11704617 |
53 | Bile secretion_Homo sapiens_hsa04976 | 1.09135290 |
54 | Huntingtons disease_Homo sapiens_hsa05016 | 1.06747913 |
55 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 1.06347535 |
56 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.04933257 |
57 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 1.00399666 |
58 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.97089285 |
59 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.96778674 |
60 | Taste transduction_Homo sapiens_hsa04742 | 0.96202860 |
61 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 0.95762861 |
62 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.90754468 |
63 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.87431895 |
64 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.85842983 |
65 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.85706367 |
66 | Histidine metabolism_Homo sapiens_hsa00340 | 0.84855632 |
67 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.83325799 |
68 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.83001158 |
69 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.82440650 |
70 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.81506218 |
71 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.79512542 |
72 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.77865013 |
73 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.76911120 |
74 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.76790444 |
75 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.75226204 |
76 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.74988355 |
77 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.74054003 |
78 | Mineral absorption_Homo sapiens_hsa04978 | 0.73493226 |
79 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.72481751 |
80 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.71476875 |
81 | Peroxisome_Homo sapiens_hsa04146 | 0.71165664 |
82 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.70310943 |
83 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.68676142 |
84 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.66792758 |
85 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.66740206 |
86 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.66682709 |
87 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.66093836 |
88 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.66052345 |
89 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.64061852 |
90 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.63530382 |
91 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.61987134 |
92 | Tight junction_Homo sapiens_hsa04530 | 0.61223849 |
93 | Long-term depression_Homo sapiens_hsa04730 | 0.60674911 |
94 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.60401188 |
95 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.60307677 |
96 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.60035131 |
97 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.59912237 |
98 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.59508350 |
99 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.59278352 |
100 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.56913704 |
101 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.55283642 |
102 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.55023959 |
103 | Cocaine addiction_Homo sapiens_hsa05030 | 0.53595408 |
104 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.52005428 |
105 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.51429696 |
106 | RNA degradation_Homo sapiens_hsa03018 | 0.50947500 |
107 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.50608260 |
108 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.48651826 |
109 | ABC transporters_Homo sapiens_hsa02010 | 0.48588390 |
110 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.48140932 |
111 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.47734958 |
112 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.47497468 |
113 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.44197704 |
114 | Insulin resistance_Homo sapiens_hsa04931 | 0.41577746 |
115 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.40784472 |
116 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.40753658 |
117 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.40186600 |
118 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.39252885 |
119 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.38736406 |