USP29

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1neuron cell-cell adhesion (GO:0007158)5.34609593
2vocalization behavior (GO:0071625)5.26015332
3regulation of short-term neuronal synaptic plasticity (GO:0048172)4.82326512
4behavioral response to nicotine (GO:0035095)4.80403393
5regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act4.61257911
6regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)4.55179016
7startle response (GO:0001964)4.43870570
8regulation of glutamate receptor signaling pathway (GO:1900449)4.36856492
9presynaptic membrane assembly (GO:0097105)4.34101110
10postsynaptic membrane organization (GO:0001941)4.26736064
11protein localization to synapse (GO:0035418)4.25255511
12platelet dense granule organization (GO:0060155)4.24588615
13synaptic vesicle exocytosis (GO:0016079)4.20166523
14positive regulation of calcium ion-dependent exocytosis (GO:0045956)4.16980674
15positive regulation of excitatory postsynaptic membrane potential (GO:2000463)4.13549954
16ionotropic glutamate receptor signaling pathway (GO:0035235)4.11460070
17epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)4.01334794
18regulation of synaptic vesicle exocytosis (GO:2000300)4.00507987
19righting reflex (GO:0060013)3.96361717
20regulation of cilium movement (GO:0003352)3.93596023
21regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.88099304
22presynaptic membrane organization (GO:0097090)3.85793734
23cornea development in camera-type eye (GO:0061303)3.85113581
24regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis (GO:00033393.83121531
25glutamate receptor signaling pathway (GO:0007215)3.72578008
26positive regulation of synaptic transmission, GABAergic (GO:0032230)3.72287481
27somite development (GO:0061053)3.69505448
28neuron-neuron synaptic transmission (GO:0007270)3.69243618
29axoneme assembly (GO:0035082)3.66020781
30neuron recognition (GO:0008038)3.63727153
31synaptic transmission, glutamatergic (GO:0035249)3.63114289
32regulation of synaptic vesicle transport (GO:1902803)3.60241670
33neurotransmitter secretion (GO:0007269)3.58731421
34epithelial cilium movement (GO:0003351)3.58062708
35detection of light stimulus involved in sensory perception (GO:0050962)3.55489527
36detection of light stimulus involved in visual perception (GO:0050908)3.55489527
37retinal cone cell development (GO:0046549)3.54437976
38protein polyglutamylation (GO:0018095)3.48954628
39negative regulation of synaptic transmission, GABAergic (GO:0032229)3.48006693
40transmission of nerve impulse (GO:0019226)3.47249556
41neurotransmitter-gated ion channel clustering (GO:0072578)3.46753993
42protein-cofactor linkage (GO:0018065)3.42194648
43RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.40720967
44tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.40720967
45positive regulation of synapse assembly (GO:0051965)3.40524834
46regulation of respiratory gaseous exchange by neurological system process (GO:0002087)3.40106766
47negative regulation of telomere maintenance (GO:0032205)3.39856006
48locomotory exploration behavior (GO:0035641)3.39541229
49fucose catabolic process (GO:0019317)3.38917569
50L-fucose metabolic process (GO:0042354)3.38917569
51L-fucose catabolic process (GO:0042355)3.38917569
52preassembly of GPI anchor in ER membrane (GO:0016254)3.37078764
53dendritic spine morphogenesis (GO:0060997)3.36098152
54synapse assembly (GO:0007416)3.33806461
55synaptic vesicle maturation (GO:0016188)3.31637422
56water-soluble vitamin biosynthetic process (GO:0042364)3.29552756
57gamma-aminobutyric acid signaling pathway (GO:0007214)3.28773648
58negative regulation of synaptic transmission, glutamatergic (GO:0051967)3.27871430
59neurotransmitter transport (GO:0006836)3.27864160
60opioid receptor signaling pathway (GO:0038003)3.25735350
61nitric oxide mediated signal transduction (GO:0007263)3.24957888
62kidney morphogenesis (GO:0060993)3.23508374
63indolalkylamine metabolic process (GO:0006586)3.22666499
64response to auditory stimulus (GO:0010996)3.20888227
65glutamate secretion (GO:0014047)3.19665001
66neural tube formation (GO:0001841)3.17156956
67magnesium ion transport (GO:0015693)3.16375576
68response to histamine (GO:0034776)3.15108919
69exploration behavior (GO:0035640)3.13838815
70regulation of synaptic transmission, GABAergic (GO:0032228)3.11358530
71membrane hyperpolarization (GO:0060081)3.11140685
72G-protein coupled glutamate receptor signaling pathway (GO:0007216)3.10927206
73auditory behavior (GO:0031223)3.10259933
74axonal fasciculation (GO:0007413)3.10183514
75long-term memory (GO:0007616)3.08677232
76regulation of synapse assembly (GO:0051963)3.07045557
77pyrimidine nucleobase catabolic process (GO:0006208)3.05898095
78mannosylation (GO:0097502)3.04839332
79regulation of synaptic transmission, glutamatergic (GO:0051966)3.04702419
80proline transport (GO:0015824)3.03861367
81regulation of cAMP-dependent protein kinase activity (GO:2000479)3.02970608
82regulation of rhodopsin mediated signaling pathway (GO:0022400)3.02490525
83membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.02117952
84synaptic vesicle endocytosis (GO:0048488)3.02069846
85gamma-aminobutyric acid transport (GO:0015812)3.01775404
86DNA deamination (GO:0045006)2.98438694
87cerebellar Purkinje cell differentiation (GO:0021702)2.98204242
88piRNA metabolic process (GO:0034587)2.98095446
89regulation of respiratory system process (GO:0044065)2.98023631
90regulation of vesicle fusion (GO:0031338)2.97175062
91neuronal action potential propagation (GO:0019227)2.96472512
92detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)2.95645938
93glycosphingolipid biosynthetic process (GO:0006688)2.95402698
94regulation of long-term neuronal synaptic plasticity (GO:0048169)2.94958678
95nonmotile primary cilium assembly (GO:0035058)2.94804371
96regulation of memory T cell differentiation (GO:0043380)2.93247283
97rhodopsin mediated signaling pathway (GO:0016056)2.92572562
98regulation of neuronal synaptic plasticity (GO:0048168)2.92487949
99regulation of synapse maturation (GO:0090128)2.91852104
100striatum development (GO:0021756)2.91313866
101regulation of postsynaptic membrane potential (GO:0060078)2.91203322
102tryptophan catabolic process (GO:0006569)2.90774120
103indole-containing compound catabolic process (GO:0042436)2.90774120
104indolalkylamine catabolic process (GO:0046218)2.90774120
105regulation of excitatory postsynaptic membrane potential (GO:0060079)2.90542956
106negative regulation of transcription regulatory region DNA binding (GO:2000678)2.89381769
107cAMP-mediated signaling (GO:0019933)2.89128362
108regulation of neurotransmitter secretion (GO:0046928)2.88837662
109regulation of neurotransmitter levels (GO:0001505)2.87676520
110cilium movement (GO:0003341)2.87106270
111pseudouridine synthesis (GO:0001522)2.86551566
112respiratory chain complex IV assembly (GO:0008535)2.85525748
113dendrite development (GO:0016358)2.84651729
114neuromuscular process controlling posture (GO:0050884)2.84453748
115cilium morphogenesis (GO:0060271)2.84373076
116glycine transport (GO:0015816)2.84337039
117DNA damage response, detection of DNA damage (GO:0042769)2.82874795
118response to pheromone (GO:0019236)2.82860949
119embryonic epithelial tube formation (GO:0001838)2.82805888
120positive regulation of membrane potential (GO:0045838)2.82317186
121detection of calcium ion (GO:0005513)2.80640052
122synaptic vesicle docking involved in exocytosis (GO:0016081)2.79935905
123behavioral response to ethanol (GO:0048149)2.79303232
124kynurenine metabolic process (GO:0070189)2.79231505
125photoreceptor cell development (GO:0042461)2.77243611
126prepulse inhibition (GO:0060134)2.75348401
127regulation of neurotransmitter transport (GO:0051588)2.74427710
128behavioral fear response (GO:0001662)2.74315539
129behavioral defense response (GO:0002209)2.74315539
130cell proliferation in forebrain (GO:0021846)2.74084134
131positive regulation of synaptic transmission, glutamatergic (GO:0051968)2.73590851
132positive regulation of prostaglandin secretion (GO:0032308)2.73054955
133nephron tubule morphogenesis (GO:0072078)2.72869377
134nephron epithelium morphogenesis (GO:0072088)2.72869377
135mechanosensory behavior (GO:0007638)2.72090170
136regulation of respiratory gaseous exchange (GO:0043576)2.71800969
137positive regulation of amino acid transport (GO:0051957)2.71559299
138parturition (GO:0007567)2.71197177
139learning (GO:0007612)2.70540990
140adult behavior (GO:0030534)2.68921417
141long-term synaptic potentiation (GO:0060291)2.67942484
142membrane depolarization (GO:0051899)2.67680429
143nephron tubule formation (GO:0072079)2.67659631
144synaptic transmission (GO:0007268)2.67424908
145GPI anchor metabolic process (GO:0006505)2.66431721
146layer formation in cerebral cortex (GO:0021819)2.66177545
147reflex (GO:0060004)2.65975586
148nucleobase catabolic process (GO:0046113)2.65577766
149regulation of glucokinase activity (GO:0033131)2.65414198
150regulation of hexokinase activity (GO:1903299)2.65414198
151protein K11-linked deubiquitination (GO:0035871)2.65218565
152ubiquinone biosynthetic process (GO:0006744)2.65118986
153innervation (GO:0060384)2.64572424
154base-excision repair, AP site formation (GO:0006285)2.63866614
155negative regulation of dendrite development (GO:2000171)2.63749727
156positive regulation of potassium ion transmembrane transporter activity (GO:1901018)2.63326304
157protein complex biogenesis (GO:0070271)2.63322879
158positive regulation of mitochondrial fission (GO:0090141)2.62216092
159rRNA modification (GO:0000154)2.62106239
160negative regulation of neurotransmitter transport (GO:0051589)2.61853287
161positive regulation of action potential (GO:0045760)2.61634332
162regulation of synapse structural plasticity (GO:0051823)2.61556708
163social behavior (GO:0035176)2.61519411
164intraspecies interaction between organisms (GO:0051703)2.61519411
165membrane depolarization during action potential (GO:0086010)2.60934936
166epithelial tube formation (GO:0072175)2.59569658
167rRNA methylation (GO:0031167)2.57340600
168cellular biogenic amine catabolic process (GO:0042402)2.57234646
169amine catabolic process (GO:0009310)2.57234646
170positive regulation of fatty acid transport (GO:2000193)2.56873252
171ubiquinone metabolic process (GO:0006743)2.55665248
172protein neddylation (GO:0045116)2.55314992
173mitochondrial calcium ion transport (GO:0006851)2.53609719
174tRNA processing (GO:0008033)2.53185638
175tryptophan metabolic process (GO:0006568)2.52199961
176limb bud formation (GO:0060174)2.52086596
177mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.51797544
178mitochondrial respiratory chain complex I assembly (GO:0032981)2.51797544
179NADH dehydrogenase complex assembly (GO:0010257)2.51797544
180multicellular organism reproduction (GO:0032504)2.51687218
181cytochrome complex assembly (GO:0017004)2.50957105
182arginine catabolic process (GO:0006527)2.48654934
183DNA double-strand break processing (GO:0000729)2.47995650
184negative regulation of mesenchymal cell apoptotic process (GO:2001054)2.47131770
185intraciliary transport (GO:0042073)2.47122475
186synaptic transmission, cholinergic (GO:0007271)2.46653309
187regulation of telomere maintenance (GO:0032204)2.45958036
188eye photoreceptor cell development (GO:0042462)2.45080082
189cilium organization (GO:0044782)2.44466281
190glycolipid biosynthetic process (GO:0009247)2.43646529
191sulfation (GO:0051923)2.42698375
192reciprocal meiotic recombination (GO:0007131)2.42497749
193reciprocal DNA recombination (GO:0035825)2.42497749
194neuronal action potential (GO:0019228)2.42050509
195positive regulation of oligodendrocyte differentiation (GO:0048714)2.41026394
196regulation of microtubule-based movement (GO:0060632)2.40490853

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.68119454
2GBX2_23144817_ChIP-Seq_PC3_Human4.13841674
3GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.73147905
4JARID2_20064375_ChIP-Seq_MESCs_Mouse2.64485082
5SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.57998458
6ZFP57_27257070_Chip-Seq_ESCs_Mouse2.56971607
7HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.42646894
8EZH2_27304074_Chip-Seq_ESCs_Mouse2.41684903
9SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.37819294
10BMI1_23680149_ChIP-Seq_NPCS_Mouse2.28404671
11TAF15_26573619_Chip-Seq_HEK293_Human2.25128988
12SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.21025308
13CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.19656337
14RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.19550290
15REST_21632747_ChIP-Seq_MESCs_Mouse2.19393617
16SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.17255806
17E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.16886013
18EED_16625203_ChIP-ChIP_MESCs_Mouse2.16074088
19IGF1R_20145208_ChIP-Seq_DFB_Human2.13617239
20JARID2_20075857_ChIP-Seq_MESCs_Mouse2.13509399
21GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.12475027
22GABP_17652178_ChIP-ChIP_JURKAT_Human2.10525843
23CTBP2_25329375_ChIP-Seq_LNCAP_Human2.05753327
24EZH2_18974828_ChIP-Seq_MESCs_Mouse2.05695122
25RNF2_18974828_ChIP-Seq_MESCs_Mouse2.05695122
26TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.03637119
27CBX2_27304074_Chip-Seq_ESCs_Mouse2.02252759
28SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.00781534
29ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.99588938
30NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.96453439
31HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.92192951
32SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.91541770
33P300_19829295_ChIP-Seq_ESCs_Human1.90735757
34POU3F2_20337985_ChIP-ChIP_501MEL_Human1.89289319
35SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.88471578
36RNF2_27304074_Chip-Seq_NSC_Mouse1.87523013
37PCGF2_27294783_Chip-Seq_ESCs_Mouse1.85143673
38EZH2_27294783_Chip-Seq_ESCs_Mouse1.85102980
39CTBP1_25329375_ChIP-Seq_LNCAP_Human1.82028502
40RNF2_27304074_Chip-Seq_ESCs_Mouse1.81322686
41MTF2_20144788_ChIP-Seq_MESCs_Mouse1.80390167
42SMAD4_21799915_ChIP-Seq_A2780_Human1.80148947
43SUZ12_27294783_Chip-Seq_ESCs_Mouse1.74461289
44FLI1_27457419_Chip-Seq_LIVER_Mouse1.73679809
45KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.69472084
46IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.69242793
47CBP_20019798_ChIP-Seq_JUKART_Human1.69242793
48* PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.68770556
49NOTCH1_21737748_ChIP-Seq_TLL_Human1.68452485
50DROSHA_22980978_ChIP-Seq_HELA_Human1.67976028
51EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.64952556
52TP53_22573176_ChIP-Seq_HFKS_Human1.57192519
53IRF1_19129219_ChIP-ChIP_H3396_Human1.56923398
54FUS_26573619_Chip-Seq_HEK293_Human1.55846353
55NANOG_18555785_Chip-Seq_ESCs_Mouse1.55628872
56MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.54497404
57TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.54128326
58POU5F1_16153702_ChIP-ChIP_HESCs_Human1.53650281
59MYC_18940864_ChIP-ChIP_HL60_Human1.53239450
60TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.52987419
61REST_18959480_ChIP-ChIP_MESCs_Mouse1.52815724
62SUZ12_27294783_Chip-Seq_NPCs_Mouse1.52511590
63BCAT_22108803_ChIP-Seq_LS180_Human1.49835191
64PIAS1_25552417_ChIP-Seq_VCAP_Human1.48456932
65* CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.48238916
66TCF4_22108803_ChIP-Seq_LS180_Human1.46873245
67TOP2B_26459242_ChIP-Seq_MCF-7_Human1.45476863
68EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.45420819
69CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.44873249
70SMAD3_21741376_ChIP-Seq_EPCs_Human1.44738343
71PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.43526368
72RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.43430902
73AR_21572438_ChIP-Seq_LNCaP_Human1.43148314
74STAT3_23295773_ChIP-Seq_U87_Human1.42541411
75CDX2_19796622_ChIP-Seq_MESCs_Mouse1.42351107
76ETV2_25802403_ChIP-Seq_MESCs_Mouse1.42129655
77ER_23166858_ChIP-Seq_MCF-7_Human1.41788343
78SMAD_19615063_ChIP-ChIP_OVARY_Human1.41650547
79P53_22387025_ChIP-Seq_ESCs_Mouse1.39852000
80E2F1_18555785_Chip-Seq_ESCs_Mouse1.37984366
81* MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.37659074
82VDR_22108803_ChIP-Seq_LS180_Human1.37621936
83NFE2_27457419_Chip-Seq_LIVER_Mouse1.37114076
84IKZF1_21737484_ChIP-ChIP_HCT116_Human1.34937874
85EST1_17652178_ChIP-ChIP_JURKAT_Human1.34913399
86PCGF2_27294783_Chip-Seq_NPCs_Mouse1.34163698
87OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.32905276
88SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.32716586
89FOXA1_27270436_Chip-Seq_PROSTATE_Human1.32541362
90FOXA1_25329375_ChIP-Seq_VCAP_Human1.32541362
91KLF5_20875108_ChIP-Seq_MESCs_Mouse1.32538880
92SUZ12_18555785_Chip-Seq_ESCs_Mouse1.31258006
93AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.31146506
94SOX2_19829295_ChIP-Seq_ESCs_Human1.30996856
95NANOG_19829295_ChIP-Seq_ESCs_Human1.30996856
96GATA3_21878914_ChIP-Seq_MCF-7_Human1.30146723
97AR_25329375_ChIP-Seq_VCAP_Human1.29459065
98CMYC_18555785_Chip-Seq_ESCs_Mouse1.29112391
99NCOR_22424771_ChIP-Seq_293T_Human1.28757417
100EGR1_23403033_ChIP-Seq_LIVER_Mouse1.28015265
101CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.27754494
102RUNX2_22187159_ChIP-Seq_PCA_Human1.27084392
103STAT3_18555785_Chip-Seq_ESCs_Mouse1.26500766
104* TCF4_23295773_ChIP-Seq_U87_Human1.26449890
105UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.26326845
106EZH2_27294783_Chip-Seq_NPCs_Mouse1.25352253
107NMYC_18555785_Chip-Seq_ESCs_Mouse1.24438876
108GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.24024406
109HOXB7_26014856_ChIP-Seq_BT474_Human1.23574204
110TP63_19390658_ChIP-ChIP_HaCaT_Human1.23375975
111VDR_23849224_ChIP-Seq_CD4+_Human1.22412658
112MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.22177819
113AR_20517297_ChIP-Seq_VCAP_Human1.21985840
114EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.21878997
115SOX2_18555785_Chip-Seq_ESCs_Mouse1.19311497
116FOXA1_21572438_ChIP-Seq_LNCaP_Human1.18408883
117P300_18555785_Chip-Seq_ESCs_Mouse1.18303646
118EWS_26573619_Chip-Seq_HEK293_Human1.18244684
119SOX2_21211035_ChIP-Seq_LN229_Gbm1.17256036
120TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.16382744
121POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.16382744
122SALL1_21062744_ChIP-ChIP_HESCs_Human1.14544840
123FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.12686928
124* SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.12339856
125TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.12310033
126RUNX1_27457419_Chip-Seq_LIVER_Mouse1.11617838
127CEBPA_26348894_ChIP-Seq_LIVER_Mouse1.11350024
128EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.10238663
129MYC_19829295_ChIP-Seq_ESCs_Human1.09731697
130P53_22127205_ChIP-Seq_FIBROBLAST_Human1.09643845
131NR3C1_21868756_ChIP-Seq_MCF10A_Human1.09611188
132TAL1_26923725_Chip-Seq_HPCs_Mouse1.09440741
133* TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.08649264
134BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.08285534
135* ZNF274_21170338_ChIP-Seq_K562_Hela1.07504891
136* CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.07265146
137OCT4_18555785_Chip-Seq_ESCs_Mouse1.06535721
138ERA_21632823_ChIP-Seq_H3396_Human1.06007421
139* KDM2B_26808549_Chip-Seq_REH_Human1.05943940
140RARB_27405468_Chip-Seq_BRAIN_Mouse1.05356837
141JUN_21703547_ChIP-Seq_K562_Human1.04976610
142LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse1.03546535
143PRDM14_20953172_ChIP-Seq_ESCs_Human1.02639865
144FOXH1_21741376_ChIP-Seq_EPCs_Human1.00909699
145FLI1_21867929_ChIP-Seq_TH2_Mouse0.98187388
146NANOG_20526341_ChIP-Seq_ESCs_Human0.96699350
147P53_21459846_ChIP-Seq_SAOS-2_Human0.96214780
148SMAD4_21741376_ChIP-Seq_EPCs_Human0.96085821
149AUTS2_25519132_ChIP-Seq_293T-REX_Human0.93779601
150CDX2_22108803_ChIP-Seq_LS180_Human0.93675835
151PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.91288483
152ETS1_20019798_ChIP-Seq_JURKAT_Human0.89457739

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003880_abnormal_central_pattern4.05818464
2MP0003122_maternal_imprinting3.59569017
3MP0004859_abnormal_synaptic_plasticity3.46244555
4MP0005645_abnormal_hypothalamus_physiol3.34381106
5MP0003787_abnormal_imprinting3.11160039
6MP0001188_hyperpigmentation3.06949628
7MP0006276_abnormal_autonomic_nervous3.06128892
8MP0003635_abnormal_synaptic_transmissio3.05474564
9MP0009046_muscle_twitch2.94577005
10MP0005423_abnormal_somatic_nervous2.84237556
11MP0009745_abnormal_behavioral_response2.69757719
12MP0005646_abnormal_pituitary_gland2.61129809
13MP0003195_calcinosis2.57865908
14MP0002063_abnormal_learning/memory/cond2.54655762
15MP0001968_abnormal_touch/_nociception2.52968815
16MP0001486_abnormal_startle_reflex2.47305004
17MP0002572_abnormal_emotion/affect_behav2.46774118
18MP0002064_seizures2.42567195
19MP0000372_irregular_coat_pigmentation2.36205549
20MP0000569_abnormal_digit_pigmentation2.27882109
21MP0002734_abnormal_mechanical_nocicepti2.23768802
22MP0003121_genomic_imprinting2.19851575
23MP0001529_abnormal_vocalization2.13542329
24MP0004270_analgesia2.12528265
25MP0002938_white_spotting2.12436946
26MP0005084_abnormal_gallbladder_morpholo2.12412126
27MP0001501_abnormal_sleep_pattern2.11581099
28MP0004133_heterotaxia2.10387611
29MP0002272_abnormal_nervous_system2.10047758
30MP0003011_delayed_dark_adaptation2.04604333
31MP0002736_abnormal_nociception_after2.00731465
32MP0002735_abnormal_chemical_nociception1.95920240
33MP0002557_abnormal_social/conspecific_i1.94275318
34MP0002638_abnormal_pupillary_reflex1.89628962
35MP0002067_abnormal_sensory_capabilities1.87768052
36MP0002184_abnormal_innervation1.84365286
37MP0010386_abnormal_urinary_bladder1.82764884
38MP0001440_abnormal_grooming_behavior1.81841998
39MP0001984_abnormal_olfaction1.74285128
40MP0000778_abnormal_nervous_system1.72320225
41MP0006292_abnormal_olfactory_placode1.71053054
42MP0002733_abnormal_thermal_nociception1.67817561
43MP0004142_abnormal_muscle_tone1.65382163
44MP0002102_abnormal_ear_morphology1.64682356
45MP0005386_behavior/neurological_phenoty1.62953794
46MP0004924_abnormal_behavior1.62953794
47MP0001970_abnormal_pain_threshold1.62895913
48MP0001502_abnormal_circadian_rhythm1.54739808
49MP0002876_abnormal_thyroid_physiology1.54142327
50MP0001905_abnormal_dopamine_level1.53455214
51MP0004019_abnormal_vitamin_homeostasis1.49970771
52MP0008995_early_reproductive_senescence1.45694530
53MP0002822_catalepsy1.41956159
54MP0005551_abnormal_eye_electrophysiolog1.41809823
55MP0002095_abnormal_skin_pigmentation1.41480097
56MP0000631_abnormal_neuroendocrine_gland1.40662569
57MP0005409_darkened_coat_color1.39710785
58MP0002837_dystrophic_cardiac_calcinosis1.34339953
59MP0000015_abnormal_ear_pigmentation1.32933575
60MP0008875_abnormal_xenobiotic_pharmacok1.31341091
61MP0002234_abnormal_pharynx_morphology1.30571487
62MP0006072_abnormal_retinal_apoptosis1.30296734
63MP0005389_reproductive_system_phenotype1.29172632
64MP0004742_abnormal_vestibular_system1.28724637
65MP0005379_endocrine/exocrine_gland_phen1.28434118
66MP0002163_abnormal_gland_morphology1.24656533
67MP0002882_abnormal_neuron_morphology1.23061838
68MP0005410_abnormal_fertilization1.22481632
69MP0001986_abnormal_taste_sensitivity1.22448027
70MP0000955_abnormal_spinal_cord1.22329053
71MP0001919_abnormal_reproductive_system1.19441508
72MP0002160_abnormal_reproductive_system1.19322175
73MP0002928_abnormal_bile_duct1.18717715
74MP0008058_abnormal_DNA_repair1.16188137
75MP0008877_abnormal_DNA_methylation1.15697506
76MP0003123_paternal_imprinting1.15258983
77MP0005377_hearing/vestibular/ear_phenot1.14944701
78MP0003878_abnormal_ear_physiology1.14944701
79MP0003646_muscle_fatigue1.14327378
80MP0002066_abnormal_motor_capabilities/c1.14307101
81MP0004147_increased_porphyrin_level1.12615738
82MP0008569_lethality_at_weaning1.12382880
83MP0004811_abnormal_neuron_physiology1.10868067
84MP0000427_abnormal_hair_cycle1.10802441
85MP0003938_abnormal_ear_development1.10232117
86MP0001963_abnormal_hearing_physiology1.07659141
87MP0000049_abnormal_middle_ear1.06101450
88MP0009780_abnormal_chondrocyte_physiolo1.04954419
89MP0002653_abnormal_ependyma_morphology1.04741108
90MP0005253_abnormal_eye_physiology1.03906847
91MP0005195_abnormal_posterior_eye1.03349052
92MP0000026_abnormal_inner_ear1.02600852
93MP0003879_abnormal_hair_cell0.97868887
94MP0000013_abnormal_adipose_tissue0.96565411
95MP0002752_abnormal_somatic_nervous0.95851840
96MP0005365_abnormal_bile_salt0.95126767
97MP0005391_vision/eye_phenotype0.94840609
98MP0002909_abnormal_adrenal_gland0.93634758
99MP0000566_synostosis0.93596773
100MP0005075_abnormal_melanosome_morpholog0.93423818
101MP0003698_abnormal_male_reproductive0.93310419
102MP0001293_anophthalmia0.92947892
103MP0002152_abnormal_brain_morphology0.92684445
104MP0002254_reproductive_system_inflammat0.92424734
105MP0005499_abnormal_olfactory_system0.91427412
106MP0005394_taste/olfaction_phenotype0.91427412
107MP0003136_yellow_coat_color0.87706632
108MP0001929_abnormal_gametogenesis0.84330466
109MP0002090_abnormal_vision0.83169458
110MP0002069_abnormal_eating/drinking_beha0.81786355
111MP0004145_abnormal_muscle_electrophysio0.81558270
112MP0005171_absent_coat_pigmentation0.80875269
113MP0002210_abnormal_sex_determination0.80567960
114MP0001764_abnormal_homeostasis0.80395914
115MP0000383_abnormal_hair_follicle0.80212748
116MP0002229_neurodegeneration0.80148362
117MP0000653_abnormal_sex_gland0.78971510
118MP0005636_abnormal_mineral_homeostasis0.77715709
119MP0005085_abnormal_gallbladder_physiolo0.75052473
120MP0002751_abnormal_autonomic_nervous0.72747090
121MP0002277_abnormal_respiratory_mucosa0.71324519
122MP0005248_abnormal_Harderian_gland0.67084733
123MP0001177_atelectasis0.66279334
124MP0005535_abnormal_body_temperature0.65694267
125MP0004085_abnormal_heartbeat0.65573392
126MP0005174_abnormal_tail_pigmentation0.63785009
127MP0001664_abnormal_digestion0.61372984
128MP0000538_abnormal_urinary_bladder0.61161617
129MP0008872_abnormal_physiological_respon0.60281436
130MP0004858_abnormal_nervous_system0.58857453
131MP0004885_abnormal_endolymph0.58812656
132MP0002177_abnormal_outer_ear0.55706897
133MP0003633_abnormal_nervous_system0.55169937
134MP0003861_abnormal_nervous_system0.54752690
135MP0004043_abnormal_pH_regulation0.54537514
136MP0001485_abnormal_pinna_reflex0.54320539
137MP0008789_abnormal_olfactory_epithelium0.53879735
138MP0009697_abnormal_copulation0.52458405
139MP0001346_abnormal_lacrimal_gland0.52416776
140MP0003385_abnormal_body_wall0.52392110
141MP0003631_nervous_system_phenotype0.51983241
142MP0001943_abnormal_respiration0.51660273
143MP0001299_abnormal_eye_distance/0.51531290
144MP0003137_abnormal_impulse_conducting0.51410877

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)5.62992371
2Febrile seizures (HP:0002373)5.28710246
3Progressive cerebellar ataxia (HP:0002073)4.03824503
4Polydipsia (HP:0001959)4.00869786
5Abnormal drinking behavior (HP:0030082)4.00869786
6Focal seizures (HP:0007359)3.94769406
7Pancreatic cysts (HP:0001737)3.86965199
8Epileptic encephalopathy (HP:0200134)3.76037445
9Hypomagnesemia (HP:0002917)3.69770817
10Atonic seizures (HP:0010819)3.64552047
11Abnormal hair whorl (HP:0010721)3.64319888
12Abnormal rod and cone electroretinograms (HP:0008323)3.54470810
13Thyroid-stimulating hormone excess (HP:0002925)3.49923058
14Myokymia (HP:0002411)3.39967189
15Generalized tonic-clonic seizures (HP:0002069)3.32775620
16Absent rod-and cone-mediated responses on ERG (HP:0007688)3.24725453
17Tetany (HP:0001281)3.18115796
18Absence seizures (HP:0002121)3.16459147
19Osteomalacia (HP:0002749)3.15513714
20Gait imbalance (HP:0002141)3.05325556
21Abnormality of the renal cortex (HP:0011035)3.00821453
22Abnormality of the renal medulla (HP:0100957)2.98029465
23Broad-based gait (HP:0002136)2.97772110
24Hypothermia (HP:0002045)2.96383278
25Limb dystonia (HP:0002451)2.94786794
26Polyuria (HP:0000103)2.93589646
27Abnormality of magnesium homeostasis (HP:0004921)2.91980910
28Polyphagia (HP:0002591)2.91789913
29Type II lissencephaly (HP:0007260)2.89984993
30Medial flaring of the eyebrow (HP:0010747)2.88319277
31Dialeptic seizures (HP:0011146)2.85454990
32Visual hallucinations (HP:0002367)2.75433929
33Excessive salivation (HP:0003781)2.75247845
34Drooling (HP:0002307)2.75247845
35Congenital primary aphakia (HP:0007707)2.72698652
36Failure to thrive in infancy (HP:0001531)2.71380857
37Agitation (HP:0000713)2.67381489
38Hyperventilation (HP:0002883)2.66532186
39Protruding tongue (HP:0010808)2.65491343
40Abnormal ciliary motility (HP:0012262)2.65479988
41Fetal akinesia sequence (HP:0001989)2.64604431
42Renal cortical cysts (HP:0000803)2.62042474
43Nephrogenic diabetes insipidus (HP:0009806)2.59025961
44Elevated circulating parathyroid hormone (PTH) level (HP:0003165)2.51204043
45Aplasia/Hypoplasia of the spleen (HP:0010451)2.49469266
46Stomach cancer (HP:0012126)2.47263565
47Absent speech (HP:0001344)2.44336986
48Chromosomal breakage induced by crosslinking agents (HP:0003221)2.41671098
49Absent/shortened dynein arms (HP:0200106)2.41067303
50Dynein arm defect of respiratory motile cilia (HP:0012255)2.41067303
51Genetic anticipation (HP:0003743)2.39684317
52Attenuation of retinal blood vessels (HP:0007843)2.38102298
53Asplenia (HP:0001746)2.38033756
54Generalized hypopigmentation of hair (HP:0011358)2.36733773
55Pendular nystagmus (HP:0012043)2.34409775
56Abnormal urine output (HP:0012590)2.33907771
57Fair hair (HP:0002286)2.33243009
58Decreased central vision (HP:0007663)2.32269762
59Abolished electroretinogram (ERG) (HP:0000550)2.31072205
60Esotropia (HP:0000565)2.30665662
61Cystic liver disease (HP:0006706)2.28180213
62Methylmalonic aciduria (HP:0012120)2.27342437
63Aplasia/Hypoplasia of the tibia (HP:0005772)2.25618453
64Aplasia/Hypoplasia of the tongue (HP:0010295)2.25371810
65Septo-optic dysplasia (HP:0100842)2.24929602
66Genital tract atresia (HP:0001827)2.24698598
67Abnormal eating behavior (HP:0100738)2.24476146
68Vaginal atresia (HP:0000148)2.23213283
69Tubulointerstitial nephritis (HP:0001970)2.22243930
70Lipid accumulation in hepatocytes (HP:0006561)2.21578613
71Abnormal respiratory motile cilium physiology (HP:0012261)2.20204080
72Delayed CNS myelination (HP:0002188)2.19707342
73Abnormality of the labia minora (HP:0012880)2.19662241
74Dysdiadochokinesis (HP:0002075)2.17138908
75Action tremor (HP:0002345)2.17056399
76Tubular atrophy (HP:0000092)2.16934783
77Short tibia (HP:0005736)2.16590054
78Abnormality of renal excretion (HP:0011036)2.15284943
79Epileptiform EEG discharges (HP:0011182)2.14785734
80Abnormality of calcium-phosphate metabolism (HP:0100530)2.13862144
81Anencephaly (HP:0002323)2.13301791
82Congenital hepatic fibrosis (HP:0002612)2.12692447
83Blue irides (HP:0000635)2.12573772
84Mitochondrial inheritance (HP:0001427)2.12290393
85Anxiety (HP:0000739)2.12172286
86Hypoplasia of the fovea (HP:0007750)2.12083015
87Aplasia/Hypoplasia of the fovea (HP:0008060)2.12083015
88Pancreatic fibrosis (HP:0100732)2.11946380
89EEG with generalized epileptiform discharges (HP:0011198)2.11215690
90Gaze-evoked nystagmus (HP:0000640)2.10245876
91Progressive inability to walk (HP:0002505)2.10169029
92Abnormality of salivation (HP:0100755)2.10013210
93Inability to walk (HP:0002540)2.09851632
94Increased hepatocellular lipid droplets (HP:0006565)2.08982305
95Abnormality of macular pigmentation (HP:0008002)2.08934927
96Methylmalonic acidemia (HP:0002912)2.06727928
97Specific learning disability (HP:0001328)2.06632783
98Abnormality of midbrain morphology (HP:0002418)2.06087616
99Molar tooth sign on MRI (HP:0002419)2.06087616
1003-Methylglutaconic aciduria (HP:0003535)2.05810659
101Congenital stationary night blindness (HP:0007642)2.04882739
102Mutism (HP:0002300)2.03534204
103Decreased circulating renin level (HP:0003351)2.02818503
104Poor coordination (HP:0002370)2.01645073
105Aplasia/Hypoplasia of the lens (HP:0008063)2.01608305
106Abnormal respiratory motile cilium morphology (HP:0005938)1.98818711
107Abnormal respiratory epithelium morphology (HP:0012253)1.98818711
108Retinal dysplasia (HP:0007973)1.98794923
109Exotropia (HP:0000577)1.98720961
110Postaxial foot polydactyly (HP:0001830)1.98534272
111Nephronophthisis (HP:0000090)1.97179623
112Truncal ataxia (HP:0002078)1.95516773
113Narrow nasal bridge (HP:0000446)1.95332494
114Lissencephaly (HP:0001339)1.95002737
115Male pseudohermaphroditism (HP:0000037)1.94790505
116Increased CSF lactate (HP:0002490)1.94592497
117Sclerocornea (HP:0000647)1.92481053
118Optic nerve hypoplasia (HP:0000609)1.92035529
119Hypsarrhythmia (HP:0002521)1.92004453
120Hemiparesis (HP:0001269)1.91501639
121Respiratory insufficiency due to defective ciliary clearance (HP:0200073)1.91321387
122Chromsome breakage (HP:0040012)1.90790700
123Bilateral microphthalmos (HP:0007633)1.89963221
124Poor suck (HP:0002033)1.88889765
125Impaired vibration sensation in the lower limbs (HP:0002166)1.88553077
126Increased corneal curvature (HP:0100692)1.88538880
127Keratoconus (HP:0000563)1.88538880
128Chronic hepatic failure (HP:0100626)1.87784351
129Acute necrotizing encephalopathy (HP:0006965)1.87625689
130Depression (HP:0000716)1.87476827
131Abnormal EKG (HP:0003115)1.86247142
132Sleep apnea (HP:0010535)1.85606206
133Urinary bladder sphincter dysfunction (HP:0002839)1.85473597
134Bony spicule pigmentary retinopathy (HP:0007737)1.85327359
135Congenital sensorineural hearing impairment (HP:0008527)1.85129071
136True hermaphroditism (HP:0010459)1.85124943
137Aplasia/hypoplasia of the uterus (HP:0008684)1.83189806
138Hip dysplasia (HP:0001385)1.82649818
139Cerebellar dysplasia (HP:0007033)1.82245818
140Papillary thyroid carcinoma (HP:0002895)1.82159424
141Poor eye contact (HP:0000817)1.81943797
142Growth hormone deficiency (HP:0000824)1.81244925
143Progressive macrocephaly (HP:0004481)1.80316860
144Oligodactyly (hands) (HP:0001180)1.79646091
145Renal Fanconi syndrome (HP:0001994)1.78968143
146Fibular aplasia (HP:0002990)1.78796580
147Median cleft lip (HP:0000161)1.78060224
148Astigmatism (HP:0000483)1.77877830
149Albinism (HP:0001022)1.75525102
150Severe muscular hypotonia (HP:0006829)1.75288353
151Pachygyria (HP:0001302)1.74943572
152Pheochromocytoma (HP:0002666)1.73959589
153Postaxial hand polydactyly (HP:0001162)1.73794176
154Decreased electroretinogram (ERG) amplitude (HP:0000654)1.73401056
155Amblyopia (HP:0000646)1.73181739
156Adrenal hypoplasia (HP:0000835)1.72876859
157Acute encephalopathy (HP:0006846)1.72797762
158Cutaneous finger syndactyly (HP:0010554)1.71559028
159Prolonged QT interval (HP:0001657)1.71057515
160Atelectasis (HP:0100750)1.70926609
161Absent eyebrow (HP:0002223)1.69083955
162Abnormality of the fovea (HP:0000493)1.69008330
163Severe visual impairment (HP:0001141)1.68794261
164Narrow forehead (HP:0000341)1.67707848
165Retinitis pigmentosa (HP:0000510)1.66596916
166Abnormal biliary tract physiology (HP:0012439)1.66184345
167Prostate neoplasm (HP:0100787)1.65408418
168Hyperthyroidism (HP:0000836)1.65243427
169Akinesia (HP:0002304)1.62656935

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CASK4.33187115
2NTRK34.00883295
3MARK13.55930948
4WNK43.48743651
5MAP2K73.48504248
6TRIM283.31421627
7TNIK3.23764347
8STK393.08804013
9MAP3K42.94733333
10MAP4K22.59535215
11NTRK22.47038977
12TAOK32.42792819
13MAP3K122.37520829
14TLK12.23103033
15MAPK132.15898979
16NUAK11.96301189
17AKT31.89120665
18MINK11.88367987
19WNK31.86554757
20EPHA41.79788938
21INSRR1.62849176
22MAP3K91.60839737
23PRPF4B1.57425860
24BMPR1B1.48704167
25MAP2K41.46999393
26BCKDK1.39711621
27ADRBK21.35594314
28SIK31.33079271
29SGK21.32943715
30TIE11.32359070
31EPHA31.31608430
32PLK21.24972848
33UHMK11.23197665
34PAK61.22318697
35ERBB31.21595555
36GRK71.20606627
37PNCK1.18823589
38BCR1.12327014
39BRD41.10300354
40YES11.09445578
41EIF2AK21.08736641
42SGK4941.08372444
43SGK2231.08372444
44CAMK2A1.08371074
45BMPR21.07348159
46PRKCG1.07157607
47BRSK11.05445224
48CDK51.04791865
49CDK31.01893990
50SIK21.01083445
51IKBKE0.97474914
52DYRK20.97306518
53IRAK10.97182360
54KSR10.96141747
55FGFR20.95305428
56IKBKB0.94156230
57GRK50.91253191
58RIPK40.90130090
59CSNK1G10.89847795
60EPHB20.88889940
61STK380.88038220
62DYRK1A0.85364474
63PKN10.81870611
64DAPK20.81727030
65SRPK10.80369640
66PRKCE0.80258840
67PRKCI0.79554946
68OXSR10.78726634
69ABL20.77357955
70TNK20.73850905
71VRK10.71995194
72FES0.71901040
73FRK0.71390017
74TGFBR10.71154356
75NEK60.70824253
76FER0.70536694
77STK38L0.69994630
78CAMK2B0.68644996
79CAMK10.68470806
80CDC42BPA0.67028515
81SGK10.66698503
82CSNK1A1L0.65941829
83MST40.65924444
84LATS20.65837631
85SGK30.65797831
86ACVR1B0.64666319
87CSNK1G20.64298175
88PRKCQ0.64110210
89BRAF0.64034104
90CDK190.63201355
91ADRBK10.62060576
92PRKD30.61603875
93NLK0.59490624
94PAK30.59381317
95NME10.59118698
96RPS6KA50.59050210
97PINK10.58605130
98MAPKAPK30.58268103
99PIK3CA0.58166337
100MKNK10.58046521
101MUSK0.58030267
102CSNK1A10.57599088
103NTRK10.54987171
104MAPK150.54777959
105MKNK20.54351387
106ZAK0.53613782
107CHUK0.53565678
108CAMK2D0.53540049
109STK160.53371341
110GRK10.53070332
111STK110.52955277
112IRAK20.50769097
113PRKG10.50192415
114DAPK10.49733354
115PRKCH0.49228402
116CAMKK20.48940937
117CDK80.48203722
118PHKG20.47135749
119PHKG10.47135749
120PRKCZ0.45742385
121ERBB40.44639985
122IGF1R0.44439549
123MAP3K60.44325706
124TEC0.43581643
125CSNK1G30.43109314
126TXK0.43025038
127BRSK20.43003689
128PRKACA0.42470661
129CDK180.42228385
130PRKCB0.42120744
131CAMK1G0.41358387
132ABL10.40011092
133OBSCN0.38628541
134TAOK20.38369885
135PRKACB0.38114853
136PLK40.37905834
137PLK30.37772507
138IRAK30.37379813
139CAMKK10.36565838
140PRKCA0.35782013
141CAMK2G0.35653631
142CAMK40.35432452
143RPS6KB10.35141776
144CSNK2A10.35107240
145MAP2K60.33471808
146KIT0.33439895
147MARK30.33077655
148DYRK30.32579733
149CSNK1E0.32291355
150NEK20.28792039
151EIF2AK30.28546937
152PLK10.28079655
153CSNK1D0.27305544
154ERBB20.26762437
155PTK2B0.25988212

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050334.64017317
2Synaptic vesicle cycle_Homo sapiens_hsa047213.26941145
3Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001303.26468008
4GABAergic synapse_Homo sapiens_hsa047272.87042097
5Morphine addiction_Homo sapiens_hsa050322.80055866
6Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.75944056
7Olfactory transduction_Homo sapiens_hsa047402.49296713
8Taste transduction_Homo sapiens_hsa047422.35072679
9Serotonergic synapse_Homo sapiens_hsa047262.32654593
10Glutamatergic synapse_Homo sapiens_hsa047242.31750198
11Circadian entrainment_Homo sapiens_hsa047132.28378200
12Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.24169651
13Insulin secretion_Homo sapiens_hsa049112.23035032
14Nitrogen metabolism_Homo sapiens_hsa009102.22074838
15Neuroactive ligand-receptor interaction_Homo sapiens_hsa040802.16702492
16Collecting duct acid secretion_Homo sapiens_hsa049662.15706821
17Amphetamine addiction_Homo sapiens_hsa050312.15553429
18Homologous recombination_Homo sapiens_hsa034402.03559396
19Cocaine addiction_Homo sapiens_hsa050302.03526857
20Butanoate metabolism_Homo sapiens_hsa006502.02919997
21Linoleic acid metabolism_Homo sapiens_hsa005912.01613360
22Dopaminergic synapse_Homo sapiens_hsa047281.98277329
23Basal transcription factors_Homo sapiens_hsa030221.92786256
24alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.92373836
25Propanoate metabolism_Homo sapiens_hsa006401.87588125
26Long-term potentiation_Homo sapiens_hsa047201.79836727
27RNA polymerase_Homo sapiens_hsa030201.72513840
28Cholinergic synapse_Homo sapiens_hsa047251.70291348
29Phototransduction_Homo sapiens_hsa047441.69778024
30Salivary secretion_Homo sapiens_hsa049701.64023728
31Long-term depression_Homo sapiens_hsa047301.61039215
32Tryptophan metabolism_Homo sapiens_hsa003801.56016035
33Type I diabetes mellitus_Homo sapiens_hsa049401.54625613
34Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.48412045
35Calcium signaling pathway_Homo sapiens_hsa040201.47187003
36Oxidative phosphorylation_Homo sapiens_hsa001901.45252038
37Selenocompound metabolism_Homo sapiens_hsa004501.42741509
38Vibrio cholerae infection_Homo sapiens_hsa051101.42197881
39Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.38954168
40Renin secretion_Homo sapiens_hsa049241.36248702
41Aldosterone synthesis and secretion_Homo sapiens_hsa049251.36092065
42Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.35714807
43Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.34062109
44Primary bile acid biosynthesis_Homo sapiens_hsa001201.31242096
45Ribosome_Homo sapiens_hsa030101.27900020
46Caffeine metabolism_Homo sapiens_hsa002321.23501196
47Intestinal immune network for IgA production_Homo sapiens_hsa046721.22967441
48Steroid biosynthesis_Homo sapiens_hsa001001.17265392
49Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.16587787
50Axon guidance_Homo sapiens_hsa043601.16437426
51Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.16278637
52Retinol metabolism_Homo sapiens_hsa008301.13972092
53RNA degradation_Homo sapiens_hsa030181.13244085
54Gastric acid secretion_Homo sapiens_hsa049711.11714153
55Type II diabetes mellitus_Homo sapiens_hsa049301.10526045
56Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.10317884
57Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051201.10243185
58Peroxisome_Homo sapiens_hsa041461.10166134
59Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.09930488
60Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.09719139
61Oxytocin signaling pathway_Homo sapiens_hsa049211.09093335
62Steroid hormone biosynthesis_Homo sapiens_hsa001401.08811934
63Cardiac muscle contraction_Homo sapiens_hsa042601.08693903
64Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.07333423
65cAMP signaling pathway_Homo sapiens_hsa040241.06520150
66Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.06439891
67Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.05100657
68GnRH signaling pathway_Homo sapiens_hsa049121.02690020
69Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.02462012
70One carbon pool by folate_Homo sapiens_hsa006701.00845581
71Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.00661648
72Chemical carcinogenesis_Homo sapiens_hsa052040.99236019
73Parkinsons disease_Homo sapiens_hsa050120.98858504
74Alzheimers disease_Homo sapiens_hsa050100.96241050
75Gap junction_Homo sapiens_hsa045400.94462658
76Rheumatoid arthritis_Homo sapiens_hsa053230.94163224
77Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.92886439
78Arachidonic acid metabolism_Homo sapiens_hsa005900.92149943
79Proteasome_Homo sapiens_hsa030500.91426514
80Melanogenesis_Homo sapiens_hsa049160.91052141
81Huntingtons disease_Homo sapiens_hsa050160.90345510
82Fatty acid elongation_Homo sapiens_hsa000620.89411983
83Phosphatidylinositol signaling system_Homo sapiens_hsa040700.88881340
84ErbB signaling pathway_Homo sapiens_hsa040120.87569370
85Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.87036427
86Vascular smooth muscle contraction_Homo sapiens_hsa042700.83613662
87Purine metabolism_Homo sapiens_hsa002300.79868879
88Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.77968657
89Ovarian steroidogenesis_Homo sapiens_hsa049130.76750838
90ABC transporters_Homo sapiens_hsa020100.74619283
91Maturity onset diabetes of the young_Homo sapiens_hsa049500.72609913
92Glycerolipid metabolism_Homo sapiens_hsa005610.71613515
93Metabolic pathways_Homo sapiens_hsa011000.70762843
94SNARE interactions in vesicular transport_Homo sapiens_hsa041300.69327046
95cGMP-PKG signaling pathway_Homo sapiens_hsa040220.68683775
96Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.67947862
97Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.67845376
98Ether lipid metabolism_Homo sapiens_hsa005650.66514956
99Fat digestion and absorption_Homo sapiens_hsa049750.64841647
100Estrogen signaling pathway_Homo sapiens_hsa049150.64719581
101Alcoholism_Homo sapiens_hsa050340.64338011
102Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.63338262
103MAPK signaling pathway_Homo sapiens_hsa040100.62754673
104Pyrimidine metabolism_Homo sapiens_hsa002400.62551013
105Regulation of autophagy_Homo sapiens_hsa041400.62410152
106Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.61933311
107Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.61557106
108beta-Alanine metabolism_Homo sapiens_hsa004100.61044371
109Phagosome_Homo sapiens_hsa041450.60391946
110Wnt signaling pathway_Homo sapiens_hsa043100.59464160
111Basal cell carcinoma_Homo sapiens_hsa052170.59421523
112Dilated cardiomyopathy_Homo sapiens_hsa054140.59326744
113Ras signaling pathway_Homo sapiens_hsa040140.58437674
114Asthma_Homo sapiens_hsa053100.57653338
115Oocyte meiosis_Homo sapiens_hsa041140.57584866
116Pancreatic secretion_Homo sapiens_hsa049720.57564790
117Fatty acid metabolism_Homo sapiens_hsa012120.57233902
118Circadian rhythm_Homo sapiens_hsa047100.54822857
119Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.54185908
120Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.54067102
121Inositol phosphate metabolism_Homo sapiens_hsa005620.51895886
122Choline metabolism in cancer_Homo sapiens_hsa052310.50766898
123Thyroid hormone synthesis_Homo sapiens_hsa049180.49820533
124Autoimmune thyroid disease_Homo sapiens_hsa053200.48981559
125Folate biosynthesis_Homo sapiens_hsa007900.48249908
126Sphingolipid metabolism_Homo sapiens_hsa006000.47537741
127Hedgehog signaling pathway_Homo sapiens_hsa043400.46568198
128Base excision repair_Homo sapiens_hsa034100.45342983
129Sulfur relay system_Homo sapiens_hsa041220.45040204
130Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.44815973
131Phospholipase D signaling pathway_Homo sapiens_hsa040720.44204615
132Fanconi anemia pathway_Homo sapiens_hsa034600.43865943
133Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.43811823
134Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.43138588
135Glioma_Homo sapiens_hsa052140.42470900
136Fatty acid degradation_Homo sapiens_hsa000710.41945783
137Dorso-ventral axis formation_Homo sapiens_hsa043200.40034230
138Protein export_Homo sapiens_hsa030600.39621463
139Mineral absorption_Homo sapiens_hsa049780.38176173
140Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.37453918
141African trypanosomiasis_Homo sapiens_hsa051430.37064707
142Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.36930371
143Mismatch repair_Homo sapiens_hsa034300.36891350
144Pentose and glucuronate interconversions_Homo sapiens_hsa000400.36225750
145Glutathione metabolism_Homo sapiens_hsa004800.36032011
146Graft-versus-host disease_Homo sapiens_hsa053320.34887521
147Cyanoamino acid metabolism_Homo sapiens_hsa004600.34834574
148Endometrial cancer_Homo sapiens_hsa052130.34592103
149Melanoma_Homo sapiens_hsa052180.34478735
150Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.32212791
151Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.30836160
152Chemokine signaling pathway_Homo sapiens_hsa040620.30329045
153Rap1 signaling pathway_Homo sapiens_hsa040150.28522079
154Glycerophospholipid metabolism_Homo sapiens_hsa005640.26606563
155Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.26204941
156Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.25160894
157Prolactin signaling pathway_Homo sapiens_hsa049170.24874508
158Allograft rejection_Homo sapiens_hsa053300.24828110
159Glucagon signaling pathway_Homo sapiens_hsa049220.22963564

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