USP3

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1neutrophil mediated immunity (GO:0002446)4.13761521
2activated T cell proliferation (GO:0050798)3.97197308
3cellular extravasation (GO:0045123)3.79005947
4histone H3-K4 trimethylation (GO:0080182)3.78274923
5modulation by symbiont of host defense response (GO:0052031)3.75893695
6modulation by organism of immune response of other organism involved in symbiotic interaction (GO:003.75893695
7modulation by organism of defense response of other organism involved in symbiotic interaction (GO:03.75893695
8positive regulation by organism of defense response of other organism involved in symbiotic interact3.75893695
9modulation by symbiont of host immune response (GO:0052553)3.75893695
10positive regulation by symbiont of host defense response (GO:0052509)3.75893695
11positive regulation of gamma-delta T cell activation (GO:0046645)3.74558284
12myeloid leukocyte mediated immunity (GO:0002444)3.72634288
13negative regulation of cell killing (GO:0031342)3.68312770
14negative regulation of leukocyte mediated cytotoxicity (GO:0001911)3.68312770
15establishment of protein localization to Golgi (GO:0072600)3.67305476
16positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)3.57343736
17microglial cell activation (GO:0001774)3.55440421
18antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G3.51890104
19protein targeting to Golgi (GO:0000042)3.50960368
20interferon-gamma production (GO:0032609)3.43482002
21protein K11-linked deubiquitination (GO:0035871)3.42324533
22histone mRNA catabolic process (GO:0071044)3.39859886
23kinetochore organization (GO:0051383)3.34153064
24tachykinin receptor signaling pathway (GO:0007217)3.30617391
25detection of molecule of bacterial origin (GO:0032490)3.28073771
26negative regulation of translation, ncRNA-mediated (GO:0040033)3.27737644
27regulation of translation, ncRNA-mediated (GO:0045974)3.27737644
28negative regulation of translation involved in gene silencing by miRNA (GO:0035278)3.27737644
29retrograde transport, vesicle recycling within Golgi (GO:0000301)3.23842030
30negative regulation of phagocytosis (GO:0050765)3.23131529
31kinetochore assembly (GO:0051382)3.23016680
32pyrimidine nucleobase catabolic process (GO:0006208)3.21876832
33negative regulation of T cell mediated immunity (GO:0002710)3.19436374
34peptidyl-lysine trimethylation (GO:0018023)3.16265512
35sequestering of actin monomers (GO:0042989)3.15191472
36dendritic cell chemotaxis (GO:0002407)3.14047924
37ribosomal small subunit assembly (GO:0000028)3.11198228
38phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092)3.08481597
39regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)3.08432343
40positive regulation of type I interferon-mediated signaling pathway (GO:0060340)3.07626836
41V(D)J recombination (GO:0033151)3.06831793
42neural tube formation (GO:0001841)3.03526696
43negative regulation of lymphocyte mediated immunity (GO:0002707)3.01685212
44positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)2.97459966
45mast cell activation (GO:0045576)2.96974204
46regulation of double-strand break repair via homologous recombination (GO:0010569)2.93513559
47neutrophil activation involved in immune response (GO:0002283)2.93299191
48negative T cell selection (GO:0043383)2.91671394
49poly(A)+ mRNA export from nucleus (GO:0016973)2.91581339
50hepatocyte apoptotic process (GO:0097284)2.91267902
51response to interleukin-15 (GO:0070672)2.89652785
52monoubiquitinated protein deubiquitination (GO:0035520)2.88756241
53olfactory bulb development (GO:0021772)2.87209781
54negative regulation of adaptive immune response based on somatic recombination of immune receptors b2.85302914
55DNA ligation (GO:0006266)2.81921420
56cellular response to ethanol (GO:0071361)2.80417697
57positive regulation of mast cell activation (GO:0033005)2.79635793
58response to UV-B (GO:0010224)2.79455822
59macrophage activation involved in immune response (GO:0002281)2.78529813
60positive regulation of interleukin-8 biosynthetic process (GO:0045416)2.78384220
61regulation of nitric-oxide synthase biosynthetic process (GO:0051769)2.78230063
62T-helper cell differentiation (GO:0042093)2.76765450
63CD4-positive, alpha-beta T cell differentiation involved in immune response (GO:0002294)2.76765450
64protein prenylation (GO:0018342)2.76149622
65prenylation (GO:0097354)2.76149622
66dendritic cell migration (GO:0036336)2.75663180
67negative regulation of interleukin-12 production (GO:0032695)2.75346659
68negative regulation of cAMP-mediated signaling (GO:0043951)2.74348043
69negative thymic T cell selection (GO:0045060)2.72256556
70regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450912.72086819
71negative regulation of adaptive immune response (GO:0002820)2.71240719
72antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)2.71218867
73antigen processing and presentation of endogenous peptide antigen (GO:0002483)2.71218867
74myeloid dendritic cell activation (GO:0001773)2.71029269
75detection of external biotic stimulus (GO:0098581)2.69657068
76regulation of MHC class II biosynthetic process (GO:0045346)2.69347443
77detection of bacterium (GO:0016045)2.67957848
78DNA double-strand break processing (GO:0000729)2.67389646
79definitive hemopoiesis (GO:0060216)2.67209129
80respiratory burst (GO:0045730)2.66795958
81B cell receptor signaling pathway (GO:0050853)2.66001248
82lymphoid progenitor cell differentiation (GO:0002320)2.65665075
83alpha-beta T cell activation (GO:0046631)2.65613550
84positive regulation of T cell mediated cytotoxicity (GO:0001916)2.65255763
85positive T cell selection (GO:0043368)2.65138836
86positive regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060213)2.64842896
87regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060211)2.64842896
88positive regulation of macrophage differentiation (GO:0045651)2.64747710
89positive regulation of interleukin-2 biosynthetic process (GO:0045086)2.64619064
90response to pheromone (GO:0019236)2.63957524
91mast cell activation involved in immune response (GO:0002279)2.63559640
92mast cell degranulation (GO:0043303)2.63559640
93T cell differentiation (GO:0030217)2.60568833
94regulation of mast cell activation (GO:0033003)2.60504785
95CD4-positive, alpha-beta T cell differentiation (GO:0043367)2.59436890
96regulation of alpha-beta T cell proliferation (GO:0046640)2.59396871
97regulation of nuclear cell cycle DNA replication (GO:0033262)2.59335727
98nucleobase catabolic process (GO:0046113)2.59085822
99macrophage activation (GO:0042116)2.58478141
100alpha-beta T cell differentiation (GO:0046632)2.57429736
101response to immune response of other organism involved in symbiotic interaction (GO:0052564)2.56228517
102response to host immune response (GO:0052572)2.56228517
103positive regulation of B cell differentiation (GO:0045579)2.54575623
104adaptation of signaling pathway (GO:0023058)2.54308773
105regulation of gamma-delta T cell activation (GO:0046643)2.54210994
106regulation of T cell receptor signaling pathway (GO:0050856)2.54090836
107myeloid cell activation involved in immune response (GO:0002275)2.53647492
108T cell homeostasis (GO:0043029)2.53170297
109positive regulation of interleukin-8 secretion (GO:2000484)2.53112065
110positive regulation of mRNA catabolic process (GO:0061014)2.53093042
111regulation of interleukin-8 secretion (GO:2000482)2.52234903
112CD4-positive, alpha-beta T cell activation (GO:0035710)2.51773289
113positive regulation of interleukin-1 beta secretion (GO:0050718)2.51448458
114negative regulation of B cell mediated immunity (GO:0002713)2.51113531
115negative regulation of immunoglobulin mediated immune response (GO:0002890)2.51113531
116negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515)2.50748116
117regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO:1900151)2.49984571
118positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO2.49984571
119lymph node development (GO:0048535)2.49852812
120leukocyte migration involved in inflammatory response (GO:0002523)2.48608522
121T cell selection (GO:0045058)2.48511106
122neutrophil activation (GO:0042119)2.47256333
123protein localization to Golgi apparatus (GO:0034067)2.46970605
124negative regulation of interleukin-1 beta production (GO:0032691)2.46619592
125regulation of interleukin-2 biosynthetic process (GO:0045076)2.46181049
126superoxide anion generation (GO:0042554)2.45420019
127keratinocyte development (GO:0003334)2.43248254
128tolerance induction (GO:0002507)2.43131521
129positive regulation of alpha-beta T cell proliferation (GO:0046641)2.42989412
130regulation of B cell receptor signaling pathway (GO:0050855)2.42870868
131antigen processing and presentation of endogenous antigen (GO:0019883)2.41625587
132alpha-beta T cell differentiation involved in immune response (GO:0002293)2.41434744
133alpha-beta T cell activation involved in immune response (GO:0002287)2.41434744
134T cell differentiation involved in immune response (GO:0002292)2.41434744
135regulation of T cell tolerance induction (GO:0002664)2.41252126
136intra-S DNA damage checkpoint (GO:0031573)2.40614622
137positive regulation of T cell chemotaxis (GO:0010820)2.39245427
138regulation of T cell chemotaxis (GO:0010819)2.39245427
139mesenchymal cell differentiation involved in kidney development (GO:0072161)2.39150629
140mesenchymal cell differentiation involved in renal system development (GO:2001012)2.39150629
141regulation of B cell differentiation (GO:0045577)2.38790485
142regulation of T cell mediated cytotoxicity (GO:0001914)2.36037761
143meiotic chromosome segregation (GO:0045132)2.36028123
144CD4-positive or CD8-positive, alpha-beta T cell lineage commitment (GO:0043369)2.34620621
145positive regulation of granulocyte differentiation (GO:0030854)2.34430615
146deoxyribonucleoside monophosphate metabolic process (GO:0009162)2.32397458
147leukocyte aggregation (GO:0070486)2.31286892
148regulation of gamma-delta T cell differentiation (GO:0045586)2.29293278
149regulation of interleukin-12 biosynthetic process (GO:0045075)2.28932773
150granulocyte activation (GO:0036230)2.28481151
151T cell migration (GO:0072678)2.28126909
152immunoglobulin mediated immune response (GO:0016064)2.27596410
153nucleotide-binding oligomerization domain containing signaling pathway (GO:0070423)2.27538253
154regulation of regulatory T cell differentiation (GO:0045589)2.27529621
155cellular response to interleukin-15 (GO:0071350)2.27500255
156lymphocyte differentiation (GO:0030098)2.26457150
157response to type I interferon (GO:0034340)2.25655836
158T cell lineage commitment (GO:0002360)2.25624688
159negative regulation of viral genome replication (GO:0045071)2.25088956
160type I interferon signaling pathway (GO:0060337)2.24980245
161cellular response to type I interferon (GO:0071357)2.24980245
162cytoplasmic pattern recognition receptor signaling pathway (GO:0002753)2.24749926
163dentate gyrus development (GO:0021542)2.24646028
164T cell activation (GO:0042110)2.24017769
165positive regulation of interleukin-2 production (GO:0032743)2.23871942
166T cell activation involved in immune response (GO:0002286)2.23363307
167regulation of antigen receptor-mediated signaling pathway (GO:0050854)2.22447813
168defense response to protozoan (GO:0042832)2.22341519
169positive regulation of interferon-gamma production (GO:0032729)2.22054333
170detection of other organism (GO:0098543)2.21982676
171somatic diversification of immune receptors via germline recombination within a single locus (GO:0002.21116923
172somatic cell DNA recombination (GO:0016444)2.21116923
173lymphocyte homeostasis (GO:0002260)2.20967136
174energy homeostasis (GO:0097009)2.19547225
175respiratory chain complex IV assembly (GO:0008535)2.19333637
176regulation of antigen processing and presentation of peptide antigen (GO:0002583)2.19287126
177B cell differentiation (GO:0030183)2.18733820
178positive thymic T cell selection (GO:0045059)2.18564212

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human6.16773774
2FOXP3_17237761_ChIP-ChIP_TREG_Mouse5.08341999
3IRF8_22096565_ChIP-ChIP_GC-B_Human4.77999106
4STAT6_20620947_ChIP-Seq_CD4_POS_T_Human3.67556336
5TP63_19390658_ChIP-ChIP_HaCaT_Human3.59140829
6IRF8_22096565_ChIP-ChIP_GC-B_Mouse3.54990863
7ELF1_17652178_ChIP-ChIP_JURKAT_Human3.37824894
8BP1_19119308_ChIP-ChIP_Hs578T_Human3.34213812
9HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse3.32963930
10RBPJ_22232070_ChIP-Seq_NCS_Mouse3.32920057
11SALL1_21062744_ChIP-ChIP_HESCs_Human3.08036136
12IRF1_21803131_ChIP-Seq_MONOCYTES_Human3.01750925
13POU3F2_20337985_ChIP-ChIP_501MEL_Human2.72475474
14SPI1_22096565_ChIP-ChIP_GC-B_Mouse2.72430879
15ZNF274_21170338_ChIP-Seq_K562_Hela2.67845554
16EGR1_19374776_ChIP-ChIP_THP-1_Human2.62631394
17NOTCH1_21737748_ChIP-Seq_TLL_Human2.60983693
18IGF1R_20145208_ChIP-Seq_DFB_Human2.59066747
19STAT3_20064451_ChIP-Seq_CD4+T_Mouse2.58279578
20CEBPD_23245923_ChIP-Seq_MEFs_Mouse2.52151516
21IRF8_21731497_ChIP-ChIP_J774_Mouse2.46155970
22FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.41236224
23MECOM_23826213_ChIP-Seq_KASUMI_Mouse2.40536808
24FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.36652609
25* SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.33176969
26TAF15_26573619_Chip-Seq_HEK293_Human2.31770368
27ZFP57_27257070_Chip-Seq_ESCs_Mouse2.26493618
28STAT4_19710469_ChIP-ChIP_TH1__Mouse2.25384633
29E2F4_17652178_ChIP-ChIP_JURKAT_Human2.21104638
30SCL_19346495_ChIP-Seq_HPC-7_Human2.15809672
31FLI1_20887958_ChIP-Seq_HPC-7_Mouse2.14251990
32HOXB4_20404135_ChIP-ChIP_EML_Mouse2.12661098
33ASXL1_24218140_ChIP-Seq_BMDM_Mouse2.12253566
34FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse2.10187894
35GBX2_23144817_ChIP-Seq_PC3_Human2.09606687
36* SPI1_23547873_ChIP-Seq_NB4_Human2.00796251
37FOXM1_23109430_ChIP-Seq_U2OS_Human1.99241277
38GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.99139224
39MYB_26560356_Chip-Seq_TH2_Human1.95781584
40VDR_22108803_ChIP-Seq_LS180_Human1.93292591
41ER_23166858_ChIP-Seq_MCF-7_Human1.87428026
42CIITA_25753668_ChIP-Seq_RAJI_Human1.84651161
43P300_19829295_ChIP-Seq_ESCs_Human1.84550252
44* AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.81911201
45EWS_26573619_Chip-Seq_HEK293_Human1.79872400
46RUNX_20019798_ChIP-Seq_JUKART_Human1.78334588
47ELK1_19687146_ChIP-ChIP_HELA_Human1.74860418
48ERG_20887958_ChIP-Seq_HPC-7_Mouse1.74786040
49SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.74588975
50SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.71637187
51RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.69706599
52FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.67933859
53MYB_26560356_Chip-Seq_TH1_Human1.66712154
54FUS_26573619_Chip-Seq_HEK293_Human1.65132881
55VDR_23849224_ChIP-Seq_CD4+_Human1.60122137
56SMAD_19615063_ChIP-ChIP_OVARY_Human1.58601607
57E2F1_21310950_ChIP-Seq_MCF-7_Human1.58551605
58* SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.57656167
59CTBP2_25329375_ChIP-Seq_LNCAP_Human1.56702017
60MAF_26560356_Chip-Seq_TH1_Human1.54673161
61KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.53971512
62* GATA3_26560356_Chip-Seq_TH2_Human1.51293151
63MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.51291471
64TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.51282219
65BCAT_22108803_ChIP-Seq_LS180_Human1.50636422
66* FOXP3_21729870_ChIP-Seq_TREG_Human1.48436650
67NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.46388451
68* UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.46091043
69* IRF8_27001747_Chip-Seq_BMDM_Mouse1.45961769
70CTBP1_25329375_ChIP-Seq_LNCAP_Human1.45302769
71MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.44370161
72CBP_20019798_ChIP-Seq_JUKART_Human1.43105541
73IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.43105541
74SMAD4_21799915_ChIP-Seq_A2780_Human1.40414962
75SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.40009802
76GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.39778480
77* PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.39247757
78FLI1_27457419_Chip-Seq_LIVER_Mouse1.38817938
79OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.38417616
80BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.37260999
81STAT3_23295773_ChIP-Seq_U87_Human1.35856515
82CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.35720926
83PCGF2_27294783_Chip-Seq_ESCs_Mouse1.33300562
84AR_25329375_ChIP-Seq_VCAP_Human1.32964610
85UTX_26944678_Chip-Seq_JUKART_Human1.31869302
86CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.30586927
87GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.28607075
88MYC_18940864_ChIP-ChIP_HL60_Human1.28140740
89VDR_24787735_ChIP-Seq_THP-1_Human1.27563804
90RUNX1_17652178_ChIP-ChIP_JURKAT_Human1.26878697
91POU5F1_16153702_ChIP-ChIP_HESCs_Human1.26012600
92PCGF2_27294783_Chip-Seq_NPCs_Mouse1.25936408
93MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.25724125
94TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.25549919
95* RUNX1_22412390_ChIP-Seq_EML_Mouse1.25276155
96PRDM14_20953172_ChIP-Seq_ESCs_Human1.25193568
97NANOG_18555785_Chip-Seq_ESCs_Mouse1.23388596
98* MYC_22102868_ChIP-Seq_BL_Human1.22880689
99VDR_24763502_ChIP-Seq_THP-1_Human1.22789809
100CDX2_19796622_ChIP-Seq_MESCs_Mouse1.22722586
101POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.22365128
102TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.22365128
103FLI1_21867929_ChIP-Seq_TH2_Mouse1.22161011
104PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.22155242
105PIAS1_25552417_ChIP-Seq_VCAP_Human1.21345234
106TCF4_22108803_ChIP-Seq_LS180_Human1.20207687
107LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.18816098
108SMAD3_21741376_ChIP-Seq_EPCs_Human1.18139235
109EST1_17652178_ChIP-ChIP_JURKAT_Human1.17161783
110CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.16098891
111TCF4_23295773_ChIP-Seq_U87_Human1.15763913
112EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.14100949
113P53_22387025_ChIP-Seq_ESCs_Mouse1.13192176
114SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.13182559
115* HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.12960173
116CRX_20693478_ChIP-Seq_RETINA_Mouse1.12952401
117GATA2_22383799_ChIP-Seq_G1ME_Mouse1.11517448
118PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.10386357
119E2F1_18555785_Chip-Seq_ESCs_Mouse1.10098845
120GATA1_22025678_ChIP-Seq_K562_Human1.09208468
121RUNX2_22187159_ChIP-Seq_PCA_Human1.08356201
122OCT4_21477851_ChIP-Seq_ESCs_Mouse1.07967450
123EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.07883961
124EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.07436622
125Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.07358426
126CMYC_18555785_Chip-Seq_ESCs_Mouse1.07229844
127SMRT_27268052_Chip-Seq_Bcells_Human1.07038755
128MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.06233339
129TOP2B_26459242_ChIP-Seq_MCF-7_Human1.05776885
130NR3C1_21868756_ChIP-Seq_MCF10A_Human1.04798252
131VDR_21846776_ChIP-Seq_THP-1_Human1.04115172
132* MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.04036669
133SOX2_18555785_ChIP-Seq_MESCs_Mouse1.03586093
134GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.02448566
135P300_18555785_Chip-Seq_ESCs_Mouse1.01270001
136PU_27001747_Chip-Seq_BMDM_Mouse1.01133228
137SRF_21415370_ChIP-Seq_HL-1_Mouse1.01015343
138NFE2_27457419_Chip-Seq_LIVER_Mouse0.99915987
139AR_21572438_ChIP-Seq_LNCaP_Human0.99646003
140* FOXA1_21572438_ChIP-Seq_LNCaP_Human0.99164690
141GABP_17652178_ChIP-ChIP_JURKAT_Human0.98341104
142LMO2_20887958_ChIP-Seq_HPC-7_Mouse0.97665879
143JARID1A_20064375_ChIP-Seq_MESCs_Mouse0.97378689
144MYB_21317192_ChIP-Seq_ERMYB_Mouse0.95861708
145KDM5B_21448134_ChIP-Seq_MESCs_Mouse0.94519247
146* GATA3_27048872_Chip-Seq_THYMUS_Human0.91560017
147NOTCH1_17114293_ChIP-ChIP_T-ALL_Human0.91550632
148TCF7_22412390_ChIP-Seq_EML_Mouse0.89225965
149IRF1_19129219_ChIP-ChIP_H3396_Human0.87132434
150RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human0.86227707
151YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse0.85961334
152MYC_18555785_ChIP-Seq_MESCs_Mouse0.85746476
153STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse0.85497808
154NMYC_18555785_Chip-Seq_ESCs_Mouse0.85364935
155FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.85253387
156SUZ12_27294783_Chip-Seq_NPCs_Mouse0.84996717
157* MAF_26560356_Chip-Seq_TH2_Human0.83418083
158NELFA_20434984_ChIP-Seq_ESCs_Mouse0.81933656
159BRD4_27068464_Chip-Seq_AML-cells_Mouse0.81609147
160PKCTHETA_26484144_Chip-Seq_BREAST_Human0.81413115
161EZH2_27294783_Chip-Seq_NPCs_Mouse0.80550767
162GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.79400588
163DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.79318668
164SUZ12_18555785_Chip-Seq_ESCs_Mouse0.77135418
165MYC_19030024_ChIP-ChIP_MESCs_Mouse0.75064338
166STAT3_18555785_Chip-Seq_ESCs_Mouse0.73673641
167CHD1_19587682_ChIP-ChIP_MESCs_Mouse0.73431419

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003763_abnormal_thymus_physiology2.94242466
2MP0001835_abnormal_antigen_presentation2.76855288
3MP0000566_synostosis2.74861664
4MP0006292_abnormal_olfactory_placode2.57389468
5MP0005671_abnormal_response_to2.53148490
6MP0008007_abnormal_cellular_replicative2.40187771
7MP0002166_altered_tumor_susceptibility2.32158258
8MP0009785_altered_susceptibility_to2.22457001
9MP0000685_abnormal_immune_system2.20746720
10MP0001188_hyperpigmentation2.20497813
11MP0002006_tumorigenesis2.18789671
12MP0002009_preneoplasia2.17397214
13MP0008058_abnormal_DNA_repair2.13306592
14MP0009379_abnormal_foot_pigmentation1.98009031
15MP0000015_abnormal_ear_pigmentation1.96047828
16MP0005174_abnormal_tail_pigmentation1.92087273
17MP0003787_abnormal_imprinting1.89047696
18MP0001800_abnormal_humoral_immune1.76426512
19MP0005310_abnormal_salivary_gland1.75540894
20MP0010094_abnormal_chromosome_stability1.73760346
21MP0002148_abnormal_hypersensitivity_rea1.72269711
22MP0002095_abnormal_skin_pigmentation1.71965828
23MP0002398_abnormal_bone_marrow1.71216500
24MP0002420_abnormal_adaptive_immunity1.66863081
25MP0001819_abnormal_immune_cell1.65265149
26MP0009333_abnormal_splenocyte_physiolog1.64301663
27MP0002452_abnormal_antigen_presenting1.63869021
28MP0005000_abnormal_immune_tolerance1.63591022
29MP0009278_abnormal_bone_marrow1.62350268
30MP0004808_abnormal_hematopoietic_stem1.61258701
31MP0002163_abnormal_gland_morphology1.60348507
32MP0004883_abnormal_blood_vessel1.59441632
33MP0005025_abnormal_response_to1.58647356
34MP0002396_abnormal_hematopoietic_system1.57672246
35MP0005387_immune_system_phenotype1.57499193
36MP0001790_abnormal_immune_system1.57499193
37MP0009697_abnormal_copulation1.56858666
38MP0008995_early_reproductive_senescence1.56651588
39MP0000703_abnormal_thymus_morphology1.55711384
40MP0002723_abnormal_immune_serum1.55040589
41MP0000490_abnormal_crypts_of1.54109352
42MP0003183_abnormal_peptide_metabolism1.52430328
43MP0000427_abnormal_hair_cycle1.51934164
44MP0002132_abnormal_respiratory_system1.50489737
45MP0003436_decreased_susceptibility_to1.49667765
46MP0000716_abnormal_immune_system1.47479369
47MP0010155_abnormal_intestine_physiology1.46786624
48MP0008789_abnormal_olfactory_epithelium1.45140203
49MP0002277_abnormal_respiratory_mucosa1.44265153
50MP0001545_abnormal_hematopoietic_system1.43610366
51MP0005397_hematopoietic_system_phenotyp1.43610366
52MP0003693_abnormal_embryo_hatching1.41205746
53MP0003786_premature_aging1.39986385
54MP0002405_respiratory_system_inflammati1.39912204
55MP0005075_abnormal_melanosome_morpholog1.39672618
56MP0003656_abnormal_erythrocyte_physiolo1.39644396
57MP0003077_abnormal_cell_cycle1.38508278
58MP0005367_renal/urinary_system_phenotyp1.36530140
59MP0000516_abnormal_urinary_system1.36530140
60MP0000689_abnormal_spleen_morphology1.35610075
61MP0002419_abnormal_innate_immunity1.34801222
62MP0003724_increased_susceptibility_to1.34292939
63MP0005409_darkened_coat_color1.33545981
64MP0009764_decreased_sensitivity_to1.33487768
65MP0002928_abnormal_bile_duct1.33429371
66MP0002722_abnormal_immune_system1.33061825
67MP0001873_stomach_inflammation1.31940010
68MP0003943_abnormal_hepatobiliary_system1.30576374
69MP0000569_abnormal_digit_pigmentation1.27563322
70MP0006082_CNS_inflammation1.26733958
71MP0008057_abnormal_DNA_replication1.25970619
72MP0002102_abnormal_ear_morphology1.25129085
73MP0010030_abnormal_orbit_morphology1.24784604
74MP0002638_abnormal_pupillary_reflex1.24307408
75MP0002429_abnormal_blood_cell1.24008604
76MP0002938_white_spotting1.21992006
77MP0001346_abnormal_lacrimal_gland1.20499154
78MP0001119_abnormal_female_reproductive1.19978409
79MP0008260_abnormal_autophagy1.19766803
80MP0000372_irregular_coat_pigmentation1.18208725
81MP0001986_abnormal_taste_sensitivity1.16901034
82MP0003252_abnormal_bile_duct1.16826457
83MP0005551_abnormal_eye_electrophysiolog1.16773276
84MP0004381_abnormal_hair_follicle1.15150765
85MP0002877_abnormal_melanocyte_morpholog1.14939816
86MP0003111_abnormal_nucleus_morphology1.13837742
87MP0003303_peritoneal_inflammation1.13699740
88MP0000465_gastrointestinal_hemorrhage1.10776726
89MP0004142_abnormal_muscle_tone1.09556659
90MP0001919_abnormal_reproductive_system1.07742428
91MP0005645_abnormal_hypothalamus_physiol1.07527768
92MP0003315_abnormal_perineum_morphology1.07084895
93MP0004043_abnormal_pH_regulation1.06292005
94MP0005253_abnormal_eye_physiology1.05504718
95MP0002160_abnormal_reproductive_system1.04904607
96MP0002098_abnormal_vibrissa_morphology1.03471394
97MP0002751_abnormal_autonomic_nervous1.03245245
98MP0000049_abnormal_middle_ear1.01573328
99MP0000678_abnormal_parathyroid_gland1.01460334
100MP0002138_abnormal_hepatobiliary_system0.99995637
101MP0005389_reproductive_system_phenotype0.98100848
102MP0000613_abnormal_salivary_gland0.97427002
103MP0003221_abnormal_cardiomyocyte_apopto0.97217208
104MP0001845_abnormal_inflammatory_respons0.96981360
105MP0005499_abnormal_olfactory_system0.96746105
106MP0005394_taste/olfaction_phenotype0.96746105
107MP0002177_abnormal_outer_ear0.96695141
108MP0002933_joint_inflammation0.95904378
109MP0002249_abnormal_larynx_morphology0.94699237
110MP0001529_abnormal_vocalization0.94276420
111MP0005408_hypopigmentation0.93518200
112MP0001879_abnormal_lymphatic_vessel0.91753639
113MP0003880_abnormal_central_pattern0.91309966
114MP0000858_altered_metastatic_potential0.90057567
115MP0000681_abnormal_thyroid_gland0.89354938
116MP0004484_altered_response_of0.88515990
117MP0003121_genomic_imprinting0.88342899
118MP0005464_abnormal_platelet_physiology0.86739188
119MP0003172_abnormal_lysosome_physiology0.86617045
120MP0005084_abnormal_gallbladder_morpholo0.86219690
121MP0003385_abnormal_body_wall0.86085141
122MP0005248_abnormal_Harderian_gland0.85635879
123MP0001764_abnormal_homeostasis0.85343312
124MP0001186_pigmentation_phenotype0.84621661
125MP0003195_calcinosis0.82471039
126MP0001270_distended_abdomen0.81479603
127MP0003866_abnormal_defecation0.80832091
128MP0002019_abnormal_tumor_incidence0.80582513
129MP0000371_diluted_coat_color0.80419413
130MP0001929_abnormal_gametogenesis0.79622593
131MP0008872_abnormal_physiological_respon0.78873889
132MP0001968_abnormal_touch/_nociception0.77230762
133MP0004924_abnormal_behavior0.76969340
134MP0005386_behavior/neurological_phenoty0.76969340
135MP0002736_abnormal_nociception_after0.74473854
136MP0006072_abnormal_retinal_apoptosis0.73972021
137MP0001501_abnormal_sleep_pattern0.73677198
138MP0008877_abnormal_DNA_methylation0.73224082
139MP0004782_abnormal_surfactant_physiolog0.72660802
140MP0003890_abnormal_embryonic-extraembry0.72450829
141MP0003045_fibrosis0.71688811
142MP0003828_pulmonary_edema0.65614741
143MP0000778_abnormal_nervous_system0.63739966

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of the fingertips (HP:0001211)4.35802908
2Thyroiditis (HP:0100646)3.76652044
3Stomatitis (HP:0010280)3.60836723
4Myositis (HP:0100614)3.43499737
5Hyperventilation (HP:0002883)3.35938137
6Optic neuritis (HP:0100653)3.21411879
7Retrobulbar optic neuritis (HP:0100654)3.21411879
8Chromosomal breakage induced by crosslinking agents (HP:0003221)3.18075452
9Severe combined immunodeficiency (HP:0004430)3.17845750
10Recurrent abscess formation (HP:0002722)3.08686425
11Hypochromic microcytic anemia (HP:0004840)3.03322352
12Chromsome breakage (HP:0040012)2.98558167
13Abnormality of the intervertebral disk (HP:0005108)2.97298831
14Pancreatic cysts (HP:0001737)2.97212840
15Abnormal delayed hypersensitivity skin test (HP:0002963)2.91276506
16Lip pit (HP:0100267)2.84528770
17Recurrent viral infections (HP:0004429)2.83683030
18Recurrent fungal infections (HP:0002841)2.79331161
19Mediastinal lymphadenopathy (HP:0100721)2.78371321
20Aplastic anemia (HP:0001915)2.78042217
21Chronic mucocutaneous candidiasis (HP:0002728)2.77533556
22Recurrent cutaneous fungal infections (HP:0011370)2.77533556
23Orchitis (HP:0100796)2.77043373
24Meningitis (HP:0001287)2.74583712
25Recurrent bacterial skin infections (HP:0005406)2.71464211
26Agammaglobulinemia (HP:0004432)2.70092995
27Reduced antithrombin III activity (HP:0001976)2.69043873
28Panhypogammaglobulinemia (HP:0003139)2.67003728
29Volvulus (HP:0002580)2.65760210
30Elevated erythrocyte sedimentation rate (HP:0003565)2.64958083
31Asymmetry of the thorax (HP:0001555)2.63756386
32Combined immunodeficiency (HP:0005387)2.63177681
33Type I transferrin isoform profile (HP:0003642)2.60235722
34Abnormality of T cell number (HP:0011839)2.58128431
35T lymphocytopenia (HP:0005403)2.51237330
36Abnormality of the renal cortex (HP:0011035)2.46391942
37Intestinal atresia (HP:0011100)2.46247146
38Thrombocytosis (HP:0001894)2.39899389
39Eczematoid dermatitis (HP:0000976)2.37493465
40Absent speech (HP:0001344)2.36969683
41IgG deficiency (HP:0004315)2.34500121
42Nephronophthisis (HP:0000090)2.33912584
43Pancreatic fibrosis (HP:0100732)2.31509928
44Abnormality of the renal medulla (HP:0100957)2.30804923
45Fair hair (HP:0002286)2.30515125
46Molar tooth sign on MRI (HP:0002419)2.30421384
47Abnormality of midbrain morphology (HP:0002418)2.30421384
48Chronic diarrhea (HP:0002028)2.30261043
49B lymphocytopenia (HP:0010976)2.29832507
50Abnormality of B cell number (HP:0010975)2.29832507
51IgM deficiency (HP:0002850)2.29208008
52Encephalitis (HP:0002383)2.28702698
53Widely spaced teeth (HP:0000687)2.28471667
54Neoplasm of the adrenal cortex (HP:0100641)2.28120953
55Abnormality of eosinophils (HP:0001879)2.27285323
56Renal cortical cysts (HP:0000803)2.25712811
57Hip dysplasia (HP:0001385)2.23730311
58Gastrointestinal infarctions (HP:0005244)2.23698429
59Medial flaring of the eyebrow (HP:0010747)2.22447138
60Abnormality of the prostate (HP:0008775)2.22282874
61Recurrent gram-negative bacterial infections (HP:0005420)2.22002883
62Abnormality of T cells (HP:0002843)2.21384989
63Hypochromic anemia (HP:0001931)2.20434051
64Recurrent skin infections (HP:0001581)2.19553424
65Reticulocytopenia (HP:0001896)2.18330201
66Prolonged bleeding time (HP:0003010)2.17019821
67Hypoproteinemia (HP:0003075)2.16223123
68Meckel diverticulum (HP:0002245)2.16082433
69Alveolar cell carcinoma (HP:0006519)2.15917391
70Ectopic kidney (HP:0000086)2.13210530
71Chronic otitis media (HP:0000389)2.10570067
72Clubbing of toes (HP:0100760)2.09605162
73Lissencephaly (HP:0001339)2.04909965
74Abnormality of DNA repair (HP:0003254)2.04861724
75Oligodactyly (hands) (HP:0001180)2.04141320
76Keratoconjunctivitis sicca (HP:0001097)2.04065595
77Eosinophilia (HP:0001880)2.02957756
78Spinal cord lesions (HP:0100561)2.02918921
79Syringomyelia (HP:0003396)2.02918921
80Leukocytosis (HP:0001974)2.01673365
81Hemoptysis (HP:0002105)2.01340066
82Chest pain (HP:0100749)2.01066711
83Abnormality of the ileum (HP:0001549)1.99553305
84Increased IgM level (HP:0003496)1.99323185
85Hypoplastic iliac wings (HP:0002866)1.98948402
86Granulocytopenia (HP:0001913)1.98536305
87Obstructive lung disease (HP:0006536)1.97488173
88Chronic obstructive pulmonary disease (HP:0006510)1.97488173
89Abnormality of macrophages (HP:0004311)1.97283989
90Abnormality of the preputium (HP:0100587)1.96366943
91Lymphopenia (HP:0001888)1.95999308
92Tented upper lip vermilion (HP:0010804)1.95347784
93Dry hair (HP:0011359)1.95308248
94Generalized hypopigmentation of hair (HP:0011358)1.94602528
95Vasculitis (HP:0002633)1.93537662
96Abnormality of cells of the lymphoid lineage (HP:0012140)1.93105783
97Trigonocephaly (HP:0000243)1.92915272
98Nephrogenic diabetes insipidus (HP:0009806)1.92376009
99Neoplasm of the tracheobronchial system (HP:0100552)1.92231133
100Abnormality of chromosome stability (HP:0003220)1.92095945
101True hermaphroditism (HP:0010459)1.91438254
102Aplasia/Hypoplasia of the uvula (HP:0010293)1.91306874
103Arterial thrombosis (HP:0004420)1.90798245
104Acute myeloid leukemia (HP:0004808)1.90241085
105Papillary thyroid carcinoma (HP:0002895)1.89241447
106Hematochezia (HP:0002573)1.86618217
107Gaze-evoked nystagmus (HP:0000640)1.86467615
108Tubulointerstitial nephritis (HP:0001970)1.85554476
109Abnormality of T cell physiology (HP:0011840)1.84914479
110Slow-growing hair (HP:0002217)1.83360246
111Abnormality of hair growth rate (HP:0011363)1.83360246
112Keratoconjunctivitis (HP:0001096)1.82786835
113Abnormality of the phalanges of the hallux (HP:0010057)1.82128541
114Optic nerve coloboma (HP:0000588)1.82064254
115Pulmonary infiltrates (HP:0002113)1.80682213
116Petechiae (HP:0000967)1.80189330
117Lymphoma (HP:0002665)1.79303118
118Aqueductal stenosis (HP:0002410)1.79159299
119Myelodysplasia (HP:0002863)1.79159242
120Periodontitis (HP:0000704)1.78572509
121Gait imbalance (HP:0002141)1.78323346
122Keratitis (HP:0000491)1.78252735
123Congenital primary aphakia (HP:0007707)1.77021387
124Hypoplasia of the thymus (HP:0000778)1.76126289
125Absent rod-and cone-mediated responses on ERG (HP:0007688)1.72362877
126Febrile seizures (HP:0002373)1.71596775
127Progressive inability to walk (HP:0002505)1.71522099
128Protruding tongue (HP:0010808)1.71517184
129Spontaneous hematomas (HP:0007420)1.70896449
130Deep philtrum (HP:0002002)1.70304198
131Nephroblastoma (Wilms tumor) (HP:0002667)1.69441323
132Amaurosis fugax (HP:0100576)1.69350985
133Chronic hepatic failure (HP:0100626)1.68455571
134Constricted visual fields (HP:0001133)1.68375324
135Sloping forehead (HP:0000340)1.68341381
136Thyroid carcinoma (HP:0002890)1.68244591
137Disproportionate short-trunk short stature (HP:0003521)1.68149308
138Azoospermia (HP:0000027)1.68035694
139Recurrent bronchitis (HP:0002837)1.67631767
140Prostate neoplasm (HP:0100787)1.67400559
141Glomerulopathy (HP:0100820)1.67267351
142Abnormality of the columella (HP:0009929)1.67103399
143Hypothermia (HP:0002045)1.66727349
144Abnormal spermatogenesis (HP:0008669)1.66646294
145Attenuation of retinal blood vessels (HP:0007843)1.66422986
146Stomach cancer (HP:0012126)1.64504478
147Acute hepatic failure (HP:0006554)1.62587344
148Abnormality of the heme biosynthetic pathway (HP:0010472)1.61684282
149Abnormal rod and cone electroretinograms (HP:0008323)1.61400748
150Pustule (HP:0200039)1.61349595
151Degeneration of the lateral corticospinal tracts (HP:0002314)1.58352392

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TXK3.31214831
2WNK33.03854265
3IRAK42.81107009
4MKNK22.50384658
5FRK2.46036568
6TLK12.23668699
7MAP3K142.22971339
8TEC2.20491667
9TRIM282.17145192
10CAMKK22.15442964
11MAP4K22.14497454
12TAOK32.12428936
13SRPK12.11397028
14NLK2.01597703
15MKNK11.98443847
16BRD41.95928959
17IRAK31.91933796
18JAK31.89101915
19ERBB31.86811166
20EEF2K1.84535755
21MAP4K11.82598735
22YES11.81399249
23FGFR21.74842942
24IKBKE1.73830269
25CLK11.71042106
26FGFR31.67637952
27ZAK1.67611280
28BCR1.65024559
29BRSK21.64276157
30MAP3K41.60891735
31ACVR1B1.59712427
32BMPR1B1.55081103
33SIK31.52464587
34TNIK1.50670662
35MARK31.49724275
36PLK41.49438301
37TGFBR11.46373861
38KIT1.44340851
39MARK11.40679362
40BTK1.39160434
41MAPK131.38034746
42CHUK1.36680465
43INSRR1.35492456
44TAOK21.33708461
45AKT31.31090602
46IKBKB1.31003490
47MAPKAPK31.28580868
48PRPF4B1.27852967
49ZAP701.25338048
50ITK1.23294965
51GRK61.20554510
52CDK81.18750789
53TYK21.16488487
54RIPK41.15772607
55BMPR21.15577190
56BLK1.10321567
57RPS6KA41.09270445
58TNK21.08258260
59MAP3K21.07646897
60CDK91.07563785
61NME21.04792484
62TRPM71.02942573
63CSK0.99156595
64STK40.98021472
65TBK10.97694554
66NUAK10.95579388
67CSNK1G20.94312002
68EIF2AK20.92988324
69PAK30.92325563
70PINK10.90847086
71OXSR10.90395111
72NEK90.89968036
73MAPK110.88981499
74PRKCQ0.88391493
75RPS6KB20.87098600
76EIF2AK30.86852276
77PASK0.86409641
78CDC70.86355705
79PIK3CG0.86226684
80SGK20.86214165
81MAP3K100.85999699
82STK390.84406706
83SYK0.81560851
84CCNB10.80927424
85FGR0.79306827
86MAP2K40.79158080
87MST40.79106000
88MAP3K120.78990484
89LCK0.77582150
90ATR0.76288169
91FES0.74419847
92DYRK30.74049087
93FGFR40.73673433
94VRK10.71198548
95CSNK1A1L0.70515883
96GRK10.69093282
97CDK120.68500217
98FLT30.68261227
99PLK20.68055511
100TAOK10.67559586
101CDK70.67415483
102LYN0.66029783
103CAMK40.65663113
104STK110.63349922
105NEK20.62924278
106PIM10.62640568
107EIF2AK10.62473289
108STK100.62256689
109KSR10.62208702
110CDK30.61689939
111JAK20.61564558
112SGK2230.60928942
113SGK4940.60928942
114CDK40.60854051
115CASK0.60586534
116CSNK1G30.60378041
117AURKB0.59590630
118EPHB20.58342185
119ADRBK20.57542624
120RPS6KB10.57214042
121DYRK20.56473716
122STK240.54748441
123CDK60.53701033
124JAK10.51455234
125CSNK1G10.51386090
126IRAK10.50869126
127CDK190.50573155
128MAP2K70.50330709
129IRAK20.50170720
130HCK0.47715690
131STK38L0.47195331
132SIK20.46589482
133PTK2B0.44500774
134EPHA30.44222100
135MAP2K60.44094059
136PKN10.43815437
137TGFBR20.43485221
138PLK10.42276648
139MELK0.41148089
140SGK30.40407038
141MAP2K30.39715758
142STK30.38947352
143CSF1R0.38835269
144PRKCE0.37282340
145HIPK20.37202642
146TIE10.36865428
147ADRBK10.36728597

Predicted pathways (KEGG)

RankGene SetZ-score
1Primary immunodeficiency_Homo sapiens_hsa053402.79691248
2Base excision repair_Homo sapiens_hsa034102.38343906
3NF-kappa B signaling pathway_Homo sapiens_hsa040642.35236576
4DNA replication_Homo sapiens_hsa030302.33701944
5Allograft rejection_Homo sapiens_hsa053302.19804179
6Cytosolic DNA-sensing pathway_Homo sapiens_hsa046232.17931572
7Intestinal immune network for IgA production_Homo sapiens_hsa046722.16923241
8Regulation of autophagy_Homo sapiens_hsa041402.07108433
9Measles_Homo sapiens_hsa051622.02184825
10Fanconi anemia pathway_Homo sapiens_hsa034601.98996534
11Graft-versus-host disease_Homo sapiens_hsa053321.94311602
12Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.93605949
13Non-homologous end-joining_Homo sapiens_hsa034501.92055368
14Herpes simplex infection_Homo sapiens_hsa051681.90022040
15Homologous recombination_Homo sapiens_hsa034401.89613077
16Mismatch repair_Homo sapiens_hsa034301.81733025
17RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.81728878
18Leishmaniasis_Homo sapiens_hsa051401.80600330
19Phototransduction_Homo sapiens_hsa047441.73258617
20Ribosome_Homo sapiens_hsa030101.69171798
21Spliceosome_Homo sapiens_hsa030401.67697403
22Hematopoietic cell lineage_Homo sapiens_hsa046401.58097735
23Transcriptional misregulation in cancer_Homo sapiens_hsa052021.55547041
24Basal transcription factors_Homo sapiens_hsa030221.53213090
25Cell cycle_Homo sapiens_hsa041101.48182976
26Toll-like receptor signaling pathway_Homo sapiens_hsa046201.47527675
27Dorso-ventral axis formation_Homo sapiens_hsa043201.46024555
28T cell receptor signaling pathway_Homo sapiens_hsa046601.40559664
29Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.40494892
30RNA polymerase_Homo sapiens_hsa030201.35196809
31Influenza A_Homo sapiens_hsa051641.33195434
32Jak-STAT signaling pathway_Homo sapiens_hsa046301.32454697
33RNA degradation_Homo sapiens_hsa030181.32113716
34Autoimmune thyroid disease_Homo sapiens_hsa053201.29717205
35NOD-like receptor signaling pathway_Homo sapiens_hsa046211.27697084
36Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.27100267
37Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.25488638
38Circadian rhythm_Homo sapiens_hsa047101.24705998
39Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.23389012
40Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.23046381
41Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.21266903
42Notch signaling pathway_Homo sapiens_hsa043301.18310634
43One carbon pool by folate_Homo sapiens_hsa006701.16801344
44Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.16212187
45Pyrimidine metabolism_Homo sapiens_hsa002401.15597926
46Nucleotide excision repair_Homo sapiens_hsa034201.13675658
47Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.10282775
48Thyroid cancer_Homo sapiens_hsa052161.09676534
49Antigen processing and presentation_Homo sapiens_hsa046121.08589565
50Asthma_Homo sapiens_hsa053101.04827100
51p53 signaling pathway_Homo sapiens_hsa041151.03699390
52TNF signaling pathway_Homo sapiens_hsa046681.03259390
53Hepatitis B_Homo sapiens_hsa051611.03073900
54Protein export_Homo sapiens_hsa030601.02556094
55alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.02042932
56B cell receptor signaling pathway_Homo sapiens_hsa046621.00207671
57Osteoclast differentiation_Homo sapiens_hsa043800.99045206
58Legionellosis_Homo sapiens_hsa051340.98101838
59Acute myeloid leukemia_Homo sapiens_hsa052210.95861905
60Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.95396615
61Nitrogen metabolism_Homo sapiens_hsa009100.93494251
62Phosphatidylinositol signaling system_Homo sapiens_hsa040700.92101797
63Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.91401306
64HTLV-I infection_Homo sapiens_hsa051660.91151439
65mRNA surveillance pathway_Homo sapiens_hsa030150.91014060
66Apoptosis_Homo sapiens_hsa042100.89402976
67Epstein-Barr virus infection_Homo sapiens_hsa051690.88450539
68Linoleic acid metabolism_Homo sapiens_hsa005910.86293340
69Viral myocarditis_Homo sapiens_hsa054160.86191194
70Ether lipid metabolism_Homo sapiens_hsa005650.86153697
71Chronic myeloid leukemia_Homo sapiens_hsa052200.85710061
72Pertussis_Homo sapiens_hsa051330.85591068
73SNARE interactions in vesicular transport_Homo sapiens_hsa041300.85039660
74Sphingolipid signaling pathway_Homo sapiens_hsa040710.84812324
75Hepatitis C_Homo sapiens_hsa051600.84349233
76Systemic lupus erythematosus_Homo sapiens_hsa053220.84108135
77Chemokine signaling pathway_Homo sapiens_hsa040620.83296834
78Toxoplasmosis_Homo sapiens_hsa051450.83078178
79Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.81950349
80Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.81609165
81Propanoate metabolism_Homo sapiens_hsa006400.81439312
82Phagosome_Homo sapiens_hsa041450.80280036
83MicroRNAs in cancer_Homo sapiens_hsa052060.77850844
84Butanoate metabolism_Homo sapiens_hsa006500.77713568
85Arachidonic acid metabolism_Homo sapiens_hsa005900.75130873
86Olfactory transduction_Homo sapiens_hsa047400.74103623
87Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.74095518
88Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.74028553
89Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.72974323
90Rheumatoid arthritis_Homo sapiens_hsa053230.72362650
91Inositol phosphate metabolism_Homo sapiens_hsa005620.72233879
92Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.71775253
93FoxO signaling pathway_Homo sapiens_hsa040680.70610662
94Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.70505662
95Type I diabetes mellitus_Homo sapiens_hsa049400.69795800
96Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.68256474
97Leukocyte transendothelial migration_Homo sapiens_hsa046700.68193660
98ABC transporters_Homo sapiens_hsa020100.68093876
99Platelet activation_Homo sapiens_hsa046110.66519230
100Prostate cancer_Homo sapiens_hsa052150.65854801
101Viral carcinogenesis_Homo sapiens_hsa052030.65698996
102Shigellosis_Homo sapiens_hsa051310.65687413
103Endometrial cancer_Homo sapiens_hsa052130.65327974
104Other glycan degradation_Homo sapiens_hsa005110.65271373
105Small cell lung cancer_Homo sapiens_hsa052220.65119692
106Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.63160538
107Malaria_Homo sapiens_hsa051440.61858428
108Purine metabolism_Homo sapiens_hsa002300.61705169
109Maturity onset diabetes of the young_Homo sapiens_hsa049500.61141338
110RNA transport_Homo sapiens_hsa030130.59220438
111Prolactin signaling pathway_Homo sapiens_hsa049170.58714107
112Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.58159391
113Basal cell carcinoma_Homo sapiens_hsa052170.58140483
114Pancreatic cancer_Homo sapiens_hsa052120.57977722
115mTOR signaling pathway_Homo sapiens_hsa041500.56559489
116Staphylococcus aureus infection_Homo sapiens_hsa051500.56003603
117Tuberculosis_Homo sapiens_hsa051520.52838540
118African trypanosomiasis_Homo sapiens_hsa051430.52490345
119Renal cell carcinoma_Homo sapiens_hsa052110.50762076
120Colorectal cancer_Homo sapiens_hsa052100.50351559
121Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.49994595
122Choline metabolism in cancer_Homo sapiens_hsa052310.49984285
123Collecting duct acid secretion_Homo sapiens_hsa049660.49410044
124Taste transduction_Homo sapiens_hsa047420.49262235
125Pathways in cancer_Homo sapiens_hsa052000.48799737
126Adherens junction_Homo sapiens_hsa045200.48351798
127Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.48216552
128Non-small cell lung cancer_Homo sapiens_hsa052230.48132441
129Type II diabetes mellitus_Homo sapiens_hsa049300.47926979
130Lysine degradation_Homo sapiens_hsa003100.47598143
131Drug metabolism - other enzymes_Homo sapiens_hsa009830.46452879
132Caffeine metabolism_Homo sapiens_hsa002320.45769798
133Steroid hormone biosynthesis_Homo sapiens_hsa001400.45391478
134Morphine addiction_Homo sapiens_hsa050320.44679454
135Glycerolipid metabolism_Homo sapiens_hsa005610.44513909
136AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.44313711
137Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.43676319
138Long-term depression_Homo sapiens_hsa047300.41928169
139Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.40439011
140Nicotine addiction_Homo sapiens_hsa050330.38889446
141Glycerophospholipid metabolism_Homo sapiens_hsa005640.37678718

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