USP34

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1nuclear pore complex assembly (GO:0051292)5.63372796
2mitotic sister chromatid cohesion (GO:0007064)5.40719168
3phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092)5.27713970
4nuclear pore organization (GO:0006999)5.10817122
5regulation of pigment cell differentiation (GO:0050932)4.27380064
6piRNA metabolic process (GO:0034587)4.26040651
7regulation of meiosis I (GO:0060631)4.12273122
8pre-miRNA processing (GO:0031054)4.00747061
9regulation of RNA export from nucleus (GO:0046831)4.00116737
10pore complex assembly (GO:0046931)3.97788862
11positive regulation of developmental pigmentation (GO:0048087)3.97677189
12cytoplasmic mRNA processing body assembly (GO:0033962)3.96257385
13cellular response to ethanol (GO:0071361)3.92166755
14histone mRNA catabolic process (GO:0071044)3.83488057
15synaptonemal complex assembly (GO:0007130)3.69525811
16sister chromatid cohesion (GO:0007062)3.66794360
17DNA methylation involved in gamete generation (GO:0043046)3.50215468
18establishment of nucleus localization (GO:0040023)3.48562555
19regulation of DNA endoreduplication (GO:0032875)3.47950459
20establishment of protein localization to Golgi (GO:0072600)3.46844145
21negative regulation of histone methylation (GO:0031061)3.39282986
22synaptonemal complex organization (GO:0070193)3.32568524
23negative regulation of translation involved in gene silencing by miRNA (GO:0035278)3.30699777
24negative regulation of translation, ncRNA-mediated (GO:0040033)3.30699777
25regulation of translation, ncRNA-mediated (GO:0045974)3.30699777
26mitotic chromosome condensation (GO:0007076)3.30212648
27regulation of nucleobase-containing compound transport (GO:0032239)3.28168475
28histone H3-K4 methylation (GO:0051568)3.27669644
29phospholipid translocation (GO:0045332)3.26812050
30lipid translocation (GO:0034204)3.26812050
31histone H3-K4 trimethylation (GO:0080182)3.25976691
32regulation of protein polyubiquitination (GO:1902914)3.25673145
33regulation of centriole replication (GO:0046599)3.25632546
34positive regulation of DNA-templated transcription, initiation (GO:2000144)3.23341417
35male meiosis (GO:0007140)3.23302982
36Golgi to endosome transport (GO:0006895)3.22426478
37protein ubiquitination involved in ubiquitin-dependent protein catabolic process (GO:0042787)3.21674553
38monoubiquitinated protein deubiquitination (GO:0035520)3.18720741
39kinetochore organization (GO:0051383)3.18391573
40gene silencing by RNA (GO:0031047)3.18133628
41retrograde transport, vesicle recycling within Golgi (GO:0000301)3.11817699
42negative regulation of DNA-dependent DNA replication (GO:2000104)3.11750220
43regulation of histone H3-K9 methylation (GO:0051570)3.11508320
44histone H3-K36 demethylation (GO:0070544)3.10379492
45histone H3-K9 methylation (GO:0051567)3.10226870
46genitalia morphogenesis (GO:0035112)3.09772270
47DNA methylation (GO:0006306)3.08360650
48DNA alkylation (GO:0006305)3.08360650
49meiotic chromosome segregation (GO:0045132)3.07893227
50positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)3.05065791
51positive regulation of mitotic sister chromatid separation (GO:1901970)3.05065791
52positive regulation of mitotic metaphase/anaphase transition (GO:0045842)3.05065791
53peptidyl-lysine trimethylation (GO:0018023)3.04467974
54stress granule assembly (GO:0034063)3.03304079
55protein targeting to Golgi (GO:0000042)3.00919886
56peptidyl-threonine phosphorylation (GO:0018107)2.98462951
57regulation of transforming growth factor beta2 production (GO:0032909)2.98364129
58histone-serine phosphorylation (GO:0035404)2.98103802
59regulation of histone H3-K27 methylation (GO:0061085)2.97239777
60pericardium development (GO:0060039)2.97172583
61negative regulation of DNA repair (GO:0045738)2.94317791
62histone lysine methylation (GO:0034968)2.92764247
63centrosome localization (GO:0051642)2.91946493
64embryonic retina morphogenesis in camera-type eye (GO:0060059)2.88964043
65histone H4-K12 acetylation (GO:0043983)2.88161038
66mRNA splice site selection (GO:0006376)2.87160780
67interkinetic nuclear migration (GO:0022027)2.84560239
68chromosome organization involved in meiosis (GO:0070192)2.83132228
69protein K11-linked deubiquitination (GO:0035871)2.81680010
70peptidyl-threonine modification (GO:0018210)2.80575298
71dosage compensation (GO:0007549)2.78533502
72histone lysine demethylation (GO:0070076)2.78507814
73paraxial mesoderm development (GO:0048339)2.77514083
74regulation of sister chromatid cohesion (GO:0007063)2.74617657
75regulation of Rac protein signal transduction (GO:0035020)2.73676653
76definitive hemopoiesis (GO:0060216)2.70898768
77NLS-bearing protein import into nucleus (GO:0006607)2.67348955
78gene silencing (GO:0016458)2.66265771
79histone demethylation (GO:0016577)2.65565552
80meiotic nuclear division (GO:0007126)2.63783086
81kinetochore assembly (GO:0051382)2.63781411
82negative regulation of histone modification (GO:0031057)2.63448859
83snRNA transcription (GO:0009301)2.63401362
84positive regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060213)2.63093210
85regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060211)2.63093210
86positive regulation of transcription from RNA polymerase III promoter (GO:0045945)2.62831665
87histone H3-K9 demethylation (GO:0033169)2.62540575
88regulation of centrosome duplication (GO:0010824)2.61112012
89sister chromatid segregation (GO:0000819)2.60495854
90embryonic camera-type eye morphogenesis (GO:0048596)2.59391969
91positive regulation of meiosis (GO:0045836)2.58609973
92histone H3-K9 modification (GO:0061647)2.57951004
93establishment of spindle orientation (GO:0051294)2.57738930
94histone methylation (GO:0016571)2.57557196
95heterochromatin organization (GO:0070828)2.56933004
96* protein K48-linked deubiquitination (GO:0071108)2.56835661
97hepatocyte apoptotic process (GO:0097284)2.56248692
98replicative senescence (GO:0090399)2.54644743
99histone H4-K16 acetylation (GO:0043984)2.54539328
100reciprocal meiotic recombination (GO:0007131)2.53210560
101reciprocal DNA recombination (GO:0035825)2.53210560
102negative regulation of neurotransmitter secretion (GO:0046929)2.53208511
103regulation of B cell receptor signaling pathway (GO:0050855)2.53205317
104regulation of establishment of cell polarity (GO:2000114)2.53043890
105B cell receptor signaling pathway (GO:0050853)2.52834484
106histone H2A monoubiquitination (GO:0035518)2.52427160
107positive regulation of granulocyte differentiation (GO:0030854)2.51232786
108negative regulation of meiosis (GO:0045835)2.50888840
109positive regulation of transcription initiation from RNA polymerase II promoter (GO:0060261)2.50648341
110labyrinthine layer development (GO:0060711)2.50297919
111nucleus organization (GO:0006997)2.49802870
112glucocorticoid receptor signaling pathway (GO:0042921)2.49718706
113regulation of mitotic spindle organization (GO:0060236)2.48553359
114histone H4-K8 acetylation (GO:0043982)2.47963378
115histone H4-K5 acetylation (GO:0043981)2.47963378
116corticosteroid receptor signaling pathway (GO:0031958)2.47783438
117early endosome to late endosome transport (GO:0045022)2.47122333
118oocyte development (GO:0048599)2.46579540
119regulation of centrosome cycle (GO:0046605)2.45890515
120microtubule depolymerization (GO:0007019)2.45768776
121negative regulation of chromatin modification (GO:1903309)2.45421605
122interleukin-6-mediated signaling pathway (GO:0070102)2.45148070
123DNA methylation or demethylation (GO:0044728)2.43700524
124attachment of spindle microtubules to kinetochore (GO:0008608)2.42941086
125regulation of establishment or maintenance of cell polarity (GO:0032878)2.42771567
126mitotic nuclear envelope disassembly (GO:0007077)2.42247501
127regulation of histone methylation (GO:0031060)2.42071550
128fibroblast migration (GO:0010761)2.41616482
129regulation of DNA methylation (GO:0044030)2.41241043
130resolution of meiotic recombination intermediates (GO:0000712)2.40608133
131peptidyl-lysine methylation (GO:0018022)2.40241950
132membrane disassembly (GO:0030397)2.39898062
133nuclear envelope disassembly (GO:0051081)2.39898062
134negative regulation of fibroblast apoptotic process (GO:2000270)2.39877330
135glycoprotein catabolic process (GO:0006516)2.38666407
136DNA synthesis involved in DNA repair (GO:0000731)2.37720029
137regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO:1900151)2.36915401
138positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO2.36915401
139nucleus localization (GO:0051647)2.36478537
140positive regulation of meiotic cell cycle (GO:0051446)2.36474900
141peptidyl-serine phosphorylation (GO:0018105)2.35884492
142microtubule anchoring (GO:0034453)2.35543061
143insulin-like growth factor receptor signaling pathway (GO:0048009)2.34800484
144protein targeting to lysosome (GO:0006622)2.34782504
145establishment of protein localization to vacuole (GO:0072666)2.34782504
146protein targeting to vacuole (GO:0006623)2.34782504
147regulation of spindle organization (GO:0090224)2.34553363
148establishment of mitotic spindle orientation (GO:0000132)2.34074464
149male sex determination (GO:0030238)2.32574062
150protein demethylation (GO:0006482)2.32343530
151protein dealkylation (GO:0008214)2.32343530
152regulation of mitotic metaphase/anaphase transition (GO:0030071)2.32208041
153male meiosis I (GO:0007141)2.31776444
154phosphatidylinositol phosphorylation (GO:0046854)2.30998475
155positive regulation of dendritic spine morphogenesis (GO:0061003)2.30905365
156cerebellar Purkinje cell differentiation (GO:0021702)2.28149507

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human5.34774992
2SALL1_21062744_ChIP-ChIP_HESCs_Human4.19500779
3FOXM1_23109430_ChIP-Seq_U2OS_Human3.28160287
4KDM5B_21448134_ChIP-Seq_MESCs_Mouse3.13292314
5BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse2.96390291
6RBPJ_22232070_ChIP-Seq_NCS_Mouse2.90974643
7FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.75264748
8ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.55394355
9GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.52345142
10CEBPD_23245923_ChIP-Seq_MEFs_Mouse2.37505649
11SMARCD1_25818293_ChIP-Seq_ESCs_Mouse2.30094331
12E2F4_17652178_ChIP-ChIP_JURKAT_Human2.27519125
13EZH2_22144423_ChIP-Seq_EOC_Human2.22788823
14FUS_26573619_Chip-Seq_HEK293_Human2.15499148
15GBX2_23144817_ChIP-Seq_PC3_Human2.15293817
16HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse2.13959624
17SMAD_19615063_ChIP-ChIP_OVARY_Human2.09292749
18CDX2_19796622_ChIP-Seq_MESCs_Mouse2.02345128
19GATA1_22025678_ChIP-Seq_K562_Human1.94342012
20POU3F2_20337985_ChIP-ChIP_501MEL_Human1.93630477
21STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.93389963
22TP63_19390658_ChIP-ChIP_HaCaT_Human1.90508019
23TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.89552517
24IGF1R_20145208_ChIP-Seq_DFB_Human1.88753513
25AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.75962338
26EGR1_19374776_ChIP-ChIP_THP-1_Human1.73230701
27* TP53_16413492_ChIP-PET_HCT116_Human1.71191123
28SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.66688823
29EWS_26573619_Chip-Seq_HEK293_Human1.63722788
30* STAT3_23295773_ChIP-Seq_U87_Human1.59885020
31HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.58757200
32FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human1.57760449
33STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.54459598
34SMAD4_21799915_ChIP-Seq_A2780_Human1.52394011
35TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.51816768
36STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.50885776
37ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.44561701
38* TCF4_23295773_ChIP-Seq_U87_Human1.44062481
39E2F1_21310950_ChIP-Seq_MCF-7_Human1.43066176
40ZNF217_24962896_ChIP-Seq_MCF-7_Human1.42069801
41FLI1_27457419_Chip-Seq_LIVER_Mouse1.41827518
42TCF4_18268006_ChIP-ChIP_LS174T_Human1.40316514
43PKCTHETA_26484144_Chip-Seq_BREAST_Human1.39831953
44CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.38705394
45SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.38246027
46RUNX_20019798_ChIP-Seq_JUKART_Human1.35716955
47TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.34484548
48POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.34484548
49Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.32219698
50DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.31852590
51TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.31628587
52CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.31315420
53EZH2_27294783_Chip-Seq_NPCs_Mouse1.28648078
54FOXO3_23340844_ChIP-Seq_DLD1_Human1.27902257
55PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.27139004
56EP300_21415370_ChIP-Seq_HL-1_Mouse1.26585464
57NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.26353086
58NRF2_20460467_ChIP-Seq_MEFs_Mouse1.26353086
59YAP1_20516196_ChIP-Seq_MESCs_Mouse1.25844649
60MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.25057976
61MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.24554267
62RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.23723863
63PCGF2_27294783_Chip-Seq_ESCs_Mouse1.22192707
64RNF2_27304074_Chip-Seq_NSC_Mouse1.20474960
65CTBP2_25329375_ChIP-Seq_LNCAP_Human1.20269041
66ZFP57_27257070_Chip-Seq_ESCs_Mouse1.19962574
67FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.19924092
68NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.19462766
69UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.18615775
70NANOG_18555785_Chip-Seq_ESCs_Mouse1.18392954
71P300_19829295_ChIP-Seq_ESCs_Human1.17306428
72ISL1_27105846_Chip-Seq_CPCs_Mouse1.16538599
73CMYC_18555785_Chip-Seq_ESCs_Mouse1.15629902
74CTBP1_25329375_ChIP-Seq_LNCAP_Human1.15441971
75ESR1_20079471_ChIP-ChIP_T-47D_Human1.15313755
76PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.13798121
77PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.13776316
78GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.13623592
79FLI1_21867929_ChIP-Seq_TH2_Mouse1.13082040
80E2F1_18555785_Chip-Seq_ESCs_Mouse1.12224853
81SOX2_21211035_ChIP-Seq_LN229_Gbm1.11299183
82CBP_20019798_ChIP-Seq_JUKART_Human1.11239278
83IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.11239278
84PIAS1_25552417_ChIP-Seq_VCAP_Human1.11145724
85* FOXA2_19822575_ChIP-Seq_HepG2_Human1.10446356
86TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.10205378
87AR_19668381_ChIP-Seq_PC3_Human1.09998386
88CTNNB1_20460455_ChIP-Seq_HCT116_Human1.09197849
89OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.08852774
90SUZ12_18555785_Chip-Seq_ESCs_Mouse1.08849228
91ARNT_22903824_ChIP-Seq_MCF-7_Human1.08117113
92YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.08047107
93P53_22387025_ChIP-Seq_ESCs_Mouse1.07542704
94PRDM14_20953172_ChIP-Seq_ESCs_Human1.06482161
95TAF15_26573619_Chip-Seq_HEK293_Human1.06349074
96SMAD3_21741376_ChIP-Seq_EPCs_Human1.05619084
97VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.05374176
98STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.04709385
99SMAD3_21741376_ChIP-Seq_HESCs_Human1.04673003
100RUNX1_17652178_ChIP-ChIP_JURKAT_Human1.04611022
101MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.04411907
102AHR_22903824_ChIP-Seq_MCF-7_Human1.03475705
103KDM2B_26808549_Chip-Seq_REH_Human1.02623008
104FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.01925169
105AR_21572438_ChIP-Seq_LNCaP_Human1.01825591
106FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.01175001
107TBX3_20139965_ChIP-Seq_ESCs_Mouse1.00538976
108PCGF2_27294783_Chip-Seq_NPCs_Mouse1.00511893
109SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.00511778
110SUZ12_27294783_Chip-Seq_NPCs_Mouse1.00102820
111SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.99895618
112TBX3_20139965_ChIP-Seq_MESCs_Mouse0.99661062
113CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.99508536
114STAT6_21828071_ChIP-Seq_BEAS2B_Human0.98139907
115RUNX2_22187159_ChIP-Seq_PCA_Human0.96236959
116ZNF274_21170338_ChIP-Seq_K562_Hela0.96173311
117SOX9_26525672_Chip-Seq_HEART_Mouse0.96068329
118EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse0.95965127
119TOP2B_26459242_ChIP-Seq_MCF-7_Human0.95947359
120BRD4_25478319_ChIP-Seq_HGPS_Human0.94694279
121AR_21909140_ChIP-Seq_LNCAP_Human0.94652452
122WT1_19549856_ChIP-ChIP_CCG9911_Human0.94445867
123FOXM1_26456572_ChIP-Seq_MCF-7_Human0.93798459
124NR3C1_21868756_ChIP-Seq_MCF10A_Human0.93648231
125CEBPB_26923725_Chip-Seq_MESODERM_Mouse0.93447653
126SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.93329064
127NFE2_27457419_Chip-Seq_LIVER_Mouse0.92581399
128ER_23166858_ChIP-Seq_MCF-7_Human0.91992745
129CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.91516210
130POU5F1_18347094_ChIP-ChIP_MESCs_Mouse0.90520699
131DROSHA_22980978_ChIP-Seq_HELA_Human0.89277557
132POU5F1_16153702_ChIP-ChIP_HESCs_Human0.89264534
133KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse0.89010022
134CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons0.88640509
135AR_25329375_ChIP-Seq_VCAP_Human0.88288619

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008877_abnormal_DNA_methylation4.39436288
2MP0000569_abnormal_digit_pigmentation4.38738292
3MP0003787_abnormal_imprinting3.49293670
4MP0003121_genomic_imprinting2.91234698
5MP0008057_abnormal_DNA_replication2.80187356
6MP0003890_abnormal_embryonic-extraembry2.60136370
7MP0010094_abnormal_chromosome_stability2.40567640
8MP0002396_abnormal_hematopoietic_system2.40337030
9MP0002166_altered_tumor_susceptibility2.32747779
10MP0003950_abnormal_plasma_membrane2.30703646
11MP0003123_paternal_imprinting2.22201728
12MP0005409_darkened_coat_color2.20163085
13MP0005076_abnormal_cell_differentiation2.16199275
14MP0003763_abnormal_thymus_physiology2.11251671
15MP0003111_abnormal_nucleus_morphology2.08171256
16MP0008058_abnormal_DNA_repair1.85100031
17MP0010307_abnormal_tumor_latency1.76875296
18MP0003077_abnormal_cell_cycle1.72048350
19MP0010352_gastrointestinal_tract_polyps1.71631149
20MP0002009_preneoplasia1.68777364
21MP0002006_tumorigenesis1.66064553
22MP0003868_abnormal_feces_composition1.65603523
23MP0002210_abnormal_sex_determination1.60692615
24MP0003122_maternal_imprinting1.57035551
25MP0003183_abnormal_peptide_metabolism1.54145967
26MP0003937_abnormal_limbs/digits/tail_de1.51982719
27MP0002084_abnormal_developmental_patter1.50611917
28MP0008995_early_reproductive_senescence1.48924133
29MP0005310_abnormal_salivary_gland1.44375770
30MP0009115_abnormal_fat_cell1.42491256
31MP0006054_spinal_hemorrhage1.41270217
32MP0003221_abnormal_cardiomyocyte_apopto1.40515283
33MP0000015_abnormal_ear_pigmentation1.40399591
34MP0001929_abnormal_gametogenesis1.40022223
35MP0008007_abnormal_cellular_replicative1.38070055
36MP0001299_abnormal_eye_distance/1.36282991
37MP0003935_abnormal_craniofacial_develop1.35594777
38MP0001145_abnormal_male_reproductive1.35057686
39MP0000537_abnormal_urethra_morphology1.33908633
40MP0004084_abnormal_cardiac_muscle1.31932490
41MP0004381_abnormal_hair_follicle1.30985300
42MP0009780_abnormal_chondrocyte_physiolo1.30471057
43MP0004197_abnormal_fetal_growth/weight/1.28535267
44MP0002085_abnormal_embryonic_tissue1.27671610
45MP0003755_abnormal_palate_morphology1.27507160
46MP0000350_abnormal_cell_proliferation1.27189989
47MP0001730_embryonic_growth_arrest1.26407115
48MP0009703_decreased_birth_body1.25791515
49MP0001915_intracranial_hemorrhage1.24210684
50MP0005187_abnormal_penis_morphology1.23805077
51MP0005380_embryogenesis_phenotype1.21304769
52MP0001672_abnormal_embryogenesis/_devel1.21304769
53MP0000653_abnormal_sex_gland1.20973497
54MP0003698_abnormal_male_reproductive1.20610569
55MP0000778_abnormal_nervous_system1.19796668
56MP0005174_abnormal_tail_pigmentation1.19279378
57MP0005623_abnormal_meninges_morphology1.18472239
58MP0005275_abnormal_skin_tensile1.17853610
59MP0000428_abnormal_craniofacial_morphol1.17575435
60MP0003861_abnormal_nervous_system1.17231071
61MP0005248_abnormal_Harderian_gland1.16924816
62MP0000427_abnormal_hair_cycle1.16549058
63MP0000432_abnormal_head_morphology1.16454649
64MP0003045_fibrosis1.14015177
65MP0003786_premature_aging1.13655385
66MP0004859_abnormal_synaptic_plasticity1.13548854
67MP0009697_abnormal_copulation1.13060233
68MP0003941_abnormal_skin_development1.11090757
69MP0003984_embryonic_growth_retardation1.10358216
70MP0002088_abnormal_embryonic_growth/wei1.08607270
71MP0002086_abnormal_extraembryonic_tissu1.08477233
72MP0001188_hyperpigmentation1.07617444
73MP0003385_abnormal_body_wall1.07110633
74MP0005621_abnormal_cell_physiology1.06520358
75MP0003656_abnormal_erythrocyte_physiolo1.06484914
76MP0010234_abnormal_vibrissa_follicle1.06441431
77MP0006072_abnormal_retinal_apoptosis1.06396272
78MP0003693_abnormal_embryo_hatching1.06220657
79MP0003632_abnormal_nervous_system1.03855129
80MP0001697_abnormal_embryo_size1.03391269
81MP0004134_abnormal_chest_morphology1.02866657
82MP0001293_anophthalmia1.02487011
83MP0003115_abnormal_respiratory_system1.00383264
84MP0004808_abnormal_hematopoietic_stem1.00257294
85MP0000733_abnormal_muscle_development1.00196674
86MP0002877_abnormal_melanocyte_morpholog0.99157492
87MP0003943_abnormal_hepatobiliary_system0.97999719
88MP0000516_abnormal_urinary_system0.97780431
89MP0005367_renal/urinary_system_phenotyp0.97780431
90MP0010678_abnormal_skin_adnexa0.97228237
91MP0002168_other_aberrant_phenotype0.95378546
92MP0003119_abnormal_digestive_system0.95368308
93MP0000631_abnormal_neuroendocrine_gland0.94176483
94MP0000703_abnormal_thymus_morphology0.94113673
95MP0002971_abnormal_brown_adipose0.92007341
96MP0002116_abnormal_craniofacial_bone0.91730566
97MP0008961_abnormal_basal_metabolism0.90739626
98MP0000383_abnormal_hair_follicle0.90499044
99MP0004957_abnormal_blastocyst_morpholog0.90141953
100MP0009672_abnormal_birth_weight0.89256318
101MP0000566_synostosis0.88755063
102MP0002697_abnormal_eye_size0.88244451
103MP0003091_abnormal_cell_migration0.87614398
104MP0004036_abnormal_muscle_relaxation0.86086642
105MP0003566_abnormal_cell_adhesion0.85831390
106MP0003705_abnormal_hypodermis_morpholog0.85364892
107MP0008932_abnormal_embryonic_tissue0.85000446
108MP0004130_abnormal_muscle_cell0.84849978
109MP0002102_abnormal_ear_morphology0.83823048
110MP0004484_altered_response_of0.81312700
111MP0001286_abnormal_eye_development0.80934450
112MP0000371_diluted_coat_color0.80636400
113MP0006292_abnormal_olfactory_placode0.79796235
114MP0002233_abnormal_nose_morphology0.79766422
115MP0003315_abnormal_perineum_morphology0.79511607
116MP0002925_abnormal_cardiovascular_devel0.79257296
117MP0004270_analgesia0.79196838
118MP0003690_abnormal_glial_cell0.77309596
119MP0010386_abnormal_urinary_bladder0.76948889
120MP0002177_abnormal_outer_ear0.76733001
121MP0002152_abnormal_brain_morphology0.75630104
122MP0003936_abnormal_reproductive_system0.74879603
123MP0001661_extended_life_span0.74690776
124MP0001879_abnormal_lymphatic_vessel0.74559787
125MP0004885_abnormal_endolymph0.74379187
126MP0005384_cellular_phenotype0.73749540
127MP0010630_abnormal_cardiac_muscle0.73517954
128MP0009053_abnormal_anal_canal0.73442918
129MP0002081_perinatal_lethality0.73223859
130MP0002114_abnormal_axial_skeleton0.72521275
131MP0001177_atelectasis0.72316474
132MP0002160_abnormal_reproductive_system0.72182378
133MP0003828_pulmonary_edema0.71961484
134MP0001784_abnormal_fluid_regulation0.71254070
135MP0005408_hypopigmentation0.69280977
136MP0003300_gastrointestinal_ulcer0.69152549
137MP0002161_abnormal_fertility/fecundity0.69086441
138MP0004264_abnormal_extraembryonic_tissu0.68909271
139MP0005551_abnormal_eye_electrophysiolog0.68792891
140MP0002109_abnormal_limb_morphology0.68736726
141MP0003567_abnormal_fetal_cardiomyocyte0.68656932
142MP0002108_abnormal_muscle_morphology0.68389460
143MP0000003_abnormal_adipose_tissue0.68124442
144MP0001835_abnormal_antigen_presentation0.68014000
145MP0000462_abnormal_digestive_system0.67703417
146MP0002398_abnormal_bone_marrow0.67564524
147MP0005220_abnormal_exocrine_pancreas0.66419465
148MP0010368_abnormal_lymphatic_system0.65373122
149MP0003252_abnormal_bile_duct0.65200835
150MP0005395_other_phenotype0.65051067
151MP0005647_abnormal_sex_gland0.62960339
152MP0001851_eye_inflammation0.62447592
153MP0003699_abnormal_female_reproductive0.61921891
154MP0000377_abnormal_hair_follicle0.61773999
155MP0002127_abnormal_cardiovascular_syste0.61341635

Predicted human phenotypes

RankGene SetZ-score
1Volvulus (HP:0002580)3.99011141
2Chromsome breakage (HP:0040012)3.10799289
3Papillary thyroid carcinoma (HP:0002895)3.04231334
4Abnormality of the fingertips (HP:0001211)2.95492159
5Chromosomal breakage induced by crosslinking agents (HP:0003221)2.85791072
6Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.84535593
7Short 4th metacarpal (HP:0010044)2.84535593
8Abnormality of the labia minora (HP:0012880)2.73040732
9Ectopic kidney (HP:0000086)2.71432612
10Macroorchidism (HP:0000053)2.62849929
11Abnormality of the nasal septum (HP:0000419)2.57828842
12Overgrowth (HP:0001548)2.49517390
13Fair hair (HP:0002286)2.49356896
14T lymphocytopenia (HP:0005403)2.42982096
15Long eyelashes (HP:0000527)2.42180125
16Absent frontal sinuses (HP:0002688)2.40981047
17Truncal obesity (HP:0001956)2.39493549
18Cone-shaped epiphyses of the phalanges of the hand (HP:0010230)2.30824348
19Obsessive-compulsive behavior (HP:0000722)2.30616384
20Narrow palate (HP:0000189)2.29985972
21Dysmetric saccades (HP:0000641)2.27586627
22Aqueductal stenosis (HP:0002410)2.23791528
23Glioma (HP:0009733)2.23767279
24Abnormality of the astrocytes (HP:0100707)2.22956465
25Astrocytoma (HP:0009592)2.22956465
26Parkinsonism with favorable response to dopaminergic medication (HP:0002548)2.21944515
27Heterotopia (HP:0002282)2.20730896
28Increased nuchal translucency (HP:0010880)2.20430364
29Curly hair (HP:0002212)2.20263491
30Vertebral arch anomaly (HP:0008438)2.19449885
31Lip pit (HP:0100267)2.17683010
32Abnormality of chromosome stability (HP:0003220)2.15751528
33Facial hemangioma (HP:0000329)2.15086906
34Genetic anticipation (HP:0003743)2.13616371
35Oligodactyly (hands) (HP:0001180)2.13026491
36Cystic hygroma (HP:0000476)2.09807682
37Renovascular hypertension (HP:0100817)2.07991162
38Rhabdomyosarcoma (HP:0002859)2.07630415
39Neoplasm of the adrenal cortex (HP:0100641)2.07222120
40Urethral obstruction (HP:0000796)2.06797861
41Medulloblastoma (HP:0002885)2.05803330
42Abnormality of T cell number (HP:0011839)2.03676598
43Generalized hypopigmentation of hair (HP:0011358)2.02502360
44Viral hepatitis (HP:0006562)2.01614834
45Oligodactyly (HP:0012165)2.01035218
46Short chin (HP:0000331)2.00773774
47Anal stenosis (HP:0002025)1.99617238
48Sandal gap (HP:0001852)1.99506762
49Submucous cleft hard palate (HP:0000176)1.99469962
50Abnormality of the epiphyses of the phalanges of the hand (HP:0005920)1.99249861
51Trigonocephaly (HP:0000243)1.98951308
52Supernumerary ribs (HP:0005815)1.97559460
53Midline defect of the nose (HP:0004122)1.96477882
54Protruding tongue (HP:0010808)1.95611979
55Excessive salivation (HP:0003781)1.94750505
56Drooling (HP:0002307)1.94750505
57Large earlobe (HP:0009748)1.94492793
58Hypoplastic labia majora (HP:0000059)1.93390098
59Gaze-evoked nystagmus (HP:0000640)1.92894878
60Subaortic stenosis (HP:0001682)1.90614138
61Abnormality of the left ventricular outflow tract (HP:0011103)1.90614138
62Spinal cord lesions (HP:0100561)1.90609315
63Syringomyelia (HP:0003396)1.90609315
64Conjunctival telangiectasia (HP:0000524)1.89839928
65Abnormality of the 4th metacarpal (HP:0010012)1.89428867
66Neoplasm of the oral cavity (HP:0100649)1.89182031
67Thyroid carcinoma (HP:0002890)1.87715824
68Abnormality of the ischium (HP:0003174)1.87698369
69Chronic hepatic failure (HP:0100626)1.86776646
70Abnormality of the epiphyses of the hand (HP:0005924)1.86020338
71Tapered finger (HP:0001182)1.85155873
72Ankyloglossia (HP:0010296)1.83560981
73Flat acetabular roof (HP:0003180)1.83265214
74Transitional cell carcinoma of the bladder (HP:0006740)1.82320845
75Hypoplasia of the maxilla (HP:0000327)1.82005867
76Deep philtrum (HP:0002002)1.79317858
77Abnormality of the carotid arteries (HP:0005344)1.79023583
78Abnormality of the radial head (HP:0003995)1.78652401
79Cubitus valgus (HP:0002967)1.78432991
80Abnormality involving the epiphyses of the upper limbs (HP:0003839)1.77415068
81Prominent nose (HP:0000448)1.75795801
82Thickened calvaria (HP:0002684)1.75158858
83Arterial tortuosity (HP:0005116)1.74650944
84Impulsivity (HP:0100710)1.74116371
85Hypopigmentation of the fundus (HP:0007894)1.73608561
86Abnormality of the labia majora (HP:0012881)1.72464300
87Neoplasm of striated muscle (HP:0009728)1.72303660
88Supernumerary bones of the axial skeleton (HP:0009144)1.72262600
89Abnormal foot bone ossification (HP:0010675)1.71995106
90Deviation of the thumb (HP:0009603)1.70332841
91Aplasia/Hypoplasia of the sternum (HP:0006714)1.70004608
92Acute lymphatic leukemia (HP:0006721)1.69589055
93Hyperacusis (HP:0010780)1.69128264
94Hepatoblastoma (HP:0002884)1.68826720
95Blue irides (HP:0000635)1.68642305
96Broad palm (HP:0001169)1.68144013
97Bladder neoplasm (HP:0009725)1.68142916
98Bladder carcinoma (HP:0002862)1.68142916
99IgA deficiency (HP:0002720)1.67990592
100Proximal placement of thumb (HP:0009623)1.67751575
101Capillary hemangiomas (HP:0005306)1.67671724
102Thoracolumbar scoliosis (HP:0002944)1.67501421
103Aplasia/Hypoplasia of the uvula (HP:0010293)1.67392094
104Pulmonic stenosis (HP:0001642)1.67248314
105Inappropriate behavior (HP:0000719)1.67245718
106Broad thumb (HP:0011304)1.66913366
107Coarse hair (HP:0002208)1.66598835
108Menstrual irregularities (HP:0000858)1.66473381
109Low anterior hairline (HP:0000294)1.65594546
110Abnormality of chromosome segregation (HP:0002916)1.65562414
111Ependymoma (HP:0002888)1.65504293
112Acute myeloid leukemia (HP:0004808)1.64558434
113Mitral valve prolapse (HP:0001634)1.63146684
114Bowel diverticulosis (HP:0005222)1.62961865
115Abnormality of the vasculature of the conjunctiva (HP:0008054)1.62137083
116Hyperkalemia (HP:0002153)1.61914088
117Abnormal hair whorl (HP:0010721)1.61894265
118Elfin facies (HP:0004428)1.61822081
119Neoplasm of the small intestine (HP:0100833)1.61754791
120Urinary bladder sphincter dysfunction (HP:0002839)1.61669582
121Nephroblastoma (Wilms tumor) (HP:0002667)1.61126770
122Widely spaced teeth (HP:0000687)1.61053031
123Aortic aneurysm (HP:0004942)1.60781135
124Broad ribs (HP:0000885)1.60587839
125Shallow orbits (HP:0000586)1.60228683
126Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)1.59723942
127Skull defect (HP:0001362)1.59518748
128Aplasia/Hypoplasia of the earlobes (HP:0009906)1.59329601
129Shawl scrotum (HP:0000049)1.58812319
130Leiomyosarcoma (HP:0100243)1.57762057
131Uterine leiomyosarcoma (HP:0002891)1.57762057
132Vesicoureteral reflux (HP:0000076)1.57601934
133Abnormality of the lower motor neuron (HP:0002366)1.56163174
134Gastrointestinal carcinoma (HP:0002672)1.56041525
135Malignant gastrointestinal tract tumors (HP:0006749)1.56041525
136Abnormality of the incisor (HP:0000676)1.55677735
137Insidious onset (HP:0003587)1.54929545
138Termporal pattern (HP:0011008)1.54929545
139Renal duplication (HP:0000075)1.52794384
140Embryonal renal neoplasm (HP:0011794)1.52178363
141Dislocated radial head (HP:0003083)1.51668074
142Relative macrocephaly (HP:0004482)1.51335725
143Biliary tract neoplasm (HP:0100574)1.51140904
144Subacute progressive viral hepatitis (HP:0006572)1.50731218
145Hereditary nonpolyposis colorectal carcinoma (HP:0006716)1.49751009
146Meckel diverticulum (HP:0002245)1.49490810
147Smooth philtrum (HP:0000319)1.48699518
148Azoospermia (HP:0000027)1.46649563
149Overriding aorta (HP:0002623)1.46482456
150Abnormality of incisor morphology (HP:0011063)1.45872468
151Thick eyebrow (HP:0000574)1.45252950
152Abnormality of the frontal sinuses (HP:0002687)1.44465051
153Abnormality of the diencephalon (HP:0010662)1.43641771
154Amyotrophic lateral sclerosis (HP:0007354)1.43374879
155Abnormal spermatogenesis (HP:0008669)1.43326627

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CDK124.99587883
2LATS14.21120293
3NEK13.79653509
4CDC73.43402498
5BRD43.01222658
6CAMK1G2.57535087
7CAMK1D2.49562115
8PNCK2.37623442
9MARK12.02714544
10NLK1.94942414
11MAP3K41.84892069
12LATS21.73099628
13STK31.72672457
14EIF2AK31.67529611
15FRK1.66039473
16MAP3K101.53686089
17NTRK31.51784017
18ZAK1.49644699
19FGFR21.49644185
20NUAK11.47068725
21PLK41.43027381
22CHEK21.42373422
23TTK1.42316622
24TRPM71.38869387
25ATR1.38682995
26STK38L1.37773404
27MKNK21.36373157
28NEK21.34161563
29SRPK11.33834316
30MELK1.33805386
31* ATM1.32390254
32WNK11.32174737
33CDK91.30486464
34NEK91.29529967
35CHEK11.27918833
36PKN21.27149558
37PLK31.26171421
38EEF2K1.23082499
39FGFR31.22764484
40YES11.22507426
41JAK11.21884303
42BMPR21.21488093
43MTOR1.21118854
44AKT31.15591303
45MAP3K141.11158635
46TEC1.10528097
47TYK21.09342389
48KSR11.09032319
49SGK21.07033278
50CDC42BPA1.06142131
51PDGFRA1.00414141
52PIK3CG1.00280128
53NTRK21.00237904
54SGK31.00076940
55PDGFRB0.99715934
56STK380.98644450
57RIPK40.97937231
58TYRO30.94095496
59ALK0.93832845
60SIK20.93718823
61STK390.92791943
62TAOK30.92538840
63ACVR1B0.92267825
64BRSK20.92172972
65BLK0.91537072
66CSNK1A1L0.91236557
67CDK60.91061198
68PLK10.90524578
69FGFR40.89105855
70SCYL20.88493038
71CDK10.88346285
72PLK20.87762226
73FGFR10.86144899
74OBSCN0.85755645
75CDK20.84577535
76MAP3K70.82303213
77MKNK10.81850146
78SGK10.81340171
79DMPK0.81218881
80PRKDC0.79352646
81CSNK1D0.79314834
82MAPK100.78512059
83PRKD30.78465017
84WNK30.77652098
85ERBB30.76560588
86PIK3CA0.75731580
87MAP3K130.73943294
88STK240.73423652
89RET0.73414394
90GSK3B0.71698390
91CAMK40.71239636
92MAPK140.70441003
93BTK0.70413318
94CAMKK20.68619672
95BCR0.67613478
96BMPR1B0.66580449
97MAPK130.65741794
98KSR20.65452314
99PRKAA20.63068169
100AURKB0.62204452
101EPHA30.62040062
102MARK30.61087665
103RPS6KB10.59684976
104CASK0.59394969
105* CSNK1E0.58485709
106MAP3K60.58439124
107PAK60.57405091
108CDK40.57245090
109MAP3K90.57222626
110RAF10.56841025
111MAP3K20.55870883
112MINK10.54595200
113CDK70.53125664
114HCK0.52580337
115MAPK80.52132509
116JAK20.51606885
117ICK0.51476380
118MET0.49606701
119DYRK1A0.49303150
120MARK20.49081100
121IKBKE0.48822359
122CDK30.48580685
123STK40.47580670
124RPS6KB20.47021257
125CSNK1G20.46156777
126MAP2K70.45466759
127SYK0.45394210
128DDR20.44966368
129INSRR0.44456370
130FER0.44164252
131ITK0.43607899
132AKT10.43532504
133RIPK10.41542660
134FLT30.41322182
135SGK4940.40854795
136SGK2230.40854795
137EGFR0.40652089
138PDK10.39787482
139STK110.39024203
140RPS6KA30.38446723
141CHUK0.38260168
142MAPK110.37785430
143NEK60.37756162
144IRAK10.37694403
145JAK30.37641716
146HIPK20.36477834
147CSNK1G10.36369297
148MAPK10.35590292
149TNIK0.34133261
150WEE10.33039996

Predicted pathways (KEGG)

RankGene SetZ-score
1mRNA surveillance pathway_Homo sapiens_hsa030151.85798012
2Fanconi anemia pathway_Homo sapiens_hsa034601.85373898
3Dorso-ventral axis formation_Homo sapiens_hsa043201.79644637
4Cell cycle_Homo sapiens_hsa041101.77864496
5B cell receptor signaling pathway_Homo sapiens_hsa046621.69409134
6Lysine degradation_Homo sapiens_hsa003101.58938503
7MicroRNAs in cancer_Homo sapiens_hsa052061.58038423
8Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.57429501
9Oocyte meiosis_Homo sapiens_hsa041141.51738709
10Non-homologous end-joining_Homo sapiens_hsa034501.49192256
11Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.40586412
12Long-term potentiation_Homo sapiens_hsa047201.40553168
13Nicotine addiction_Homo sapiens_hsa050331.39319019
14Adherens junction_Homo sapiens_hsa045201.38766505
15AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.35259387
16RNA transport_Homo sapiens_hsa030131.35065151
17Acute myeloid leukemia_Homo sapiens_hsa052211.34300694
18Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.30204892
19Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.29546100
20TGF-beta signaling pathway_Homo sapiens_hsa043501.29116714
21Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.28108847
22Thyroid cancer_Homo sapiens_hsa052161.28041564
23Thyroid hormone signaling pathway_Homo sapiens_hsa049191.27809577
24Type II diabetes mellitus_Homo sapiens_hsa049301.27338880
25Phototransduction_Homo sapiens_hsa047441.27153205
26mTOR signaling pathway_Homo sapiens_hsa041501.25589573
27Basal cell carcinoma_Homo sapiens_hsa052171.24995552
28Wnt signaling pathway_Homo sapiens_hsa043101.21923147
29Hippo signaling pathway_Homo sapiens_hsa043901.19781603
30Phosphatidylinositol signaling system_Homo sapiens_hsa040701.16450188
31Prostate cancer_Homo sapiens_hsa052151.15958069
32Axon guidance_Homo sapiens_hsa043601.14856925
33Colorectal cancer_Homo sapiens_hsa052101.14645658
34Platelet activation_Homo sapiens_hsa046111.14149938
35ErbB signaling pathway_Homo sapiens_hsa040121.13204805
36Endometrial cancer_Homo sapiens_hsa052131.13031005
37Basal transcription factors_Homo sapiens_hsa030221.12808043
38Jak-STAT signaling pathway_Homo sapiens_hsa046301.12617723
39Glioma_Homo sapiens_hsa052141.12488243
40RNA degradation_Homo sapiens_hsa030181.11892491
41Hepatitis B_Homo sapiens_hsa051611.08238884
42Circadian entrainment_Homo sapiens_hsa047131.00709552
43Fatty acid biosynthesis_Homo sapiens_hsa000611.00609726
44Estrogen signaling pathway_Homo sapiens_hsa049150.99149883
45Hedgehog signaling pathway_Homo sapiens_hsa043400.98272645
46Small cell lung cancer_Homo sapiens_hsa052220.97948856
47Choline metabolism in cancer_Homo sapiens_hsa052310.96672249
48Amphetamine addiction_Homo sapiens_hsa050310.96398263
49Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.95450840
50Dopaminergic synapse_Homo sapiens_hsa047280.95185867
51Renin secretion_Homo sapiens_hsa049240.94922473
52Chronic myeloid leukemia_Homo sapiens_hsa052200.93757069
53Glutamatergic synapse_Homo sapiens_hsa047240.93587080
54HTLV-I infection_Homo sapiens_hsa051660.93108831
55Long-term depression_Homo sapiens_hsa047300.93095627
56cGMP-PKG signaling pathway_Homo sapiens_hsa040220.93070617
57FoxO signaling pathway_Homo sapiens_hsa040680.91923867
58Proteoglycans in cancer_Homo sapiens_hsa052050.90308985
59Taste transduction_Homo sapiens_hsa047420.89654681
60Pancreatic cancer_Homo sapiens_hsa052120.89312440
61Renal cell carcinoma_Homo sapiens_hsa052110.89130863
62cAMP signaling pathway_Homo sapiens_hsa040240.89112027
63Measles_Homo sapiens_hsa051620.88481368
64Melanogenesis_Homo sapiens_hsa049160.88262657
65p53 signaling pathway_Homo sapiens_hsa041150.88232933
66Oxytocin signaling pathway_Homo sapiens_hsa049210.87680048
67Insulin resistance_Homo sapiens_hsa049310.86920465
68GnRH signaling pathway_Homo sapiens_hsa049120.86555414
69Non-small cell lung cancer_Homo sapiens_hsa052230.86389550
70Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.85750243
71MAPK signaling pathway_Homo sapiens_hsa040100.85667379
72Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.85459427
73Focal adhesion_Homo sapiens_hsa045100.84939052
74Homologous recombination_Homo sapiens_hsa034400.84823284
75Longevity regulating pathway - mammal_Homo sapiens_hsa042110.84655916
76Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.84598379
77Transcriptional misregulation in cancer_Homo sapiens_hsa052020.84470068
78Morphine addiction_Homo sapiens_hsa050320.83953468
79Insulin secretion_Homo sapiens_hsa049110.83104715
80Viral carcinogenesis_Homo sapiens_hsa052030.82623533
81Sphingolipid signaling pathway_Homo sapiens_hsa040710.82460107
82Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.82247592
83Aldosterone synthesis and secretion_Homo sapiens_hsa049250.80980442
84Cholinergic synapse_Homo sapiens_hsa047250.80381429
85Melanoma_Homo sapiens_hsa052180.79785855
86Osteoclast differentiation_Homo sapiens_hsa043800.79728396
87Pathways in cancer_Homo sapiens_hsa052000.79669949
88Hepatitis C_Homo sapiens_hsa051600.79668786
89Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.79657101
90Alcoholism_Homo sapiens_hsa050340.79560450
91ABC transporters_Homo sapiens_hsa020100.79175163
92Inositol phosphate metabolism_Homo sapiens_hsa005620.78868032
93VEGF signaling pathway_Homo sapiens_hsa043700.78767781
94Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.78444070
95Salivary secretion_Homo sapiens_hsa049700.76772905
96Mismatch repair_Homo sapiens_hsa034300.76414031
97ECM-receptor interaction_Homo sapiens_hsa045120.76028733
98Toxoplasmosis_Homo sapiens_hsa051450.75409358
99Prolactin signaling pathway_Homo sapiens_hsa049170.74957361
100Spliceosome_Homo sapiens_hsa030400.72100817
101Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.71370279
102Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.71227841
103Tight junction_Homo sapiens_hsa045300.70800133
104Regulation of actin cytoskeleton_Homo sapiens_hsa048100.70538831
105Neurotrophin signaling pathway_Homo sapiens_hsa047220.69952572
106Phospholipase D signaling pathway_Homo sapiens_hsa040720.69111528
107T cell receptor signaling pathway_Homo sapiens_hsa046600.68568259
108Leukocyte transendothelial migration_Homo sapiens_hsa046700.67584996
109Gap junction_Homo sapiens_hsa045400.67094609
110Olfactory transduction_Homo sapiens_hsa047400.66567278
111Influenza A_Homo sapiens_hsa051640.66393621
112Insulin signaling pathway_Homo sapiens_hsa049100.65255872
113NF-kappa B signaling pathway_Homo sapiens_hsa040640.65028207
114GABAergic synapse_Homo sapiens_hsa047270.64856655
115Ras signaling pathway_Homo sapiens_hsa040140.64203581
116Gastric acid secretion_Homo sapiens_hsa049710.63720062
117Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.63315641
118Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.63213685
119Circadian rhythm_Homo sapiens_hsa047100.63159694
120Systemic lupus erythematosus_Homo sapiens_hsa053220.63057582
121Rap1 signaling pathway_Homo sapiens_hsa040150.62788149
122Glucagon signaling pathway_Homo sapiens_hsa049220.62761189
123Vascular smooth muscle contraction_Homo sapiens_hsa042700.62376338
124Serotonergic synapse_Homo sapiens_hsa047260.60338196
125NOD-like receptor signaling pathway_Homo sapiens_hsa046210.58730304
126Amoebiasis_Homo sapiens_hsa051460.58256856
127PI3K-Akt signaling pathway_Homo sapiens_hsa041510.57631630
128HIF-1 signaling pathway_Homo sapiens_hsa040660.57105984
129TNF signaling pathway_Homo sapiens_hsa046680.56671980
130Thyroid hormone synthesis_Homo sapiens_hsa049180.55914236
131Chemokine signaling pathway_Homo sapiens_hsa040620.55587570
132Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.54795601

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