USP42

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1piRNA metabolic process (GO:0034587)5.18590330
2nuclear pore complex assembly (GO:0051292)5.15796934
3nuclear pore organization (GO:0006999)4.55668223
4behavioral response to nicotine (GO:0035095)4.49022505
5pyrimidine nucleobase catabolic process (GO:0006208)4.41252461
6microtubule depolymerization (GO:0007019)4.36499334
7cilium or flagellum-dependent cell motility (GO:0001539)4.33744818
8mitotic sister chromatid cohesion (GO:0007064)4.26491895
9male meiosis (GO:0007140)4.16270396
10pore complex assembly (GO:0046931)4.15599604
11synaptonemal complex assembly (GO:0007130)3.92512519
12meiotic chromosome segregation (GO:0045132)3.87769358
13cell proliferation in forebrain (GO:0021846)3.83851746
14synaptonemal complex organization (GO:0070193)3.80591548
15somite development (GO:0061053)3.71191118
16kinetochore organization (GO:0051383)3.64397446
17monoubiquitinated protein deubiquitination (GO:0035520)3.60118075
18DNA methylation involved in gamete generation (GO:0043046)3.59411686
19histone H2A acetylation (GO:0043968)3.56202175
20axonemal dynein complex assembly (GO:0070286)3.55661956
21DNA topological change (GO:0006265)3.53771386
22meiotic nuclear division (GO:0007126)3.53423302
23negative regulation of transcription regulatory region DNA binding (GO:2000678)3.52434650
24sister chromatid cohesion (GO:0007062)3.51403889
25sperm-egg recognition (GO:0035036)3.47739239
26fusion of sperm to egg plasma membrane (GO:0007342)3.47165305
27centriole replication (GO:0007099)3.46753438
28regulation of meiosis I (GO:0060631)3.41999924
29chromosome organization involved in meiosis (GO:0070192)3.40250930
30negative regulation of organelle assembly (GO:1902116)3.39382426
31sperm motility (GO:0030317)3.36776779
32establishment of protein localization to Golgi (GO:0072600)3.35862570
33mitotic metaphase plate congression (GO:0007080)3.34876908
34kinetochore assembly (GO:0051382)3.30288160
35nonmotile primary cilium assembly (GO:0035058)3.29699806
36binding of sperm to zona pellucida (GO:0007339)3.29135033
37male meiosis I (GO:0007141)3.28833337
38acrosome assembly (GO:0001675)3.24345437
39nucleobase catabolic process (GO:0046113)3.24178601
40multicellular organism reproduction (GO:0032504)3.24092993
41cerebral cortex radially oriented cell migration (GO:0021799)3.23084675
42protein targeting to Golgi (GO:0000042)3.22185520
43regulation of cilium movement (GO:0003352)3.19861193
44protein polyglutamylation (GO:0018095)3.19602607
45gene silencing by RNA (GO:0031047)3.18532090
46protein localization to chromosome, centromeric region (GO:0071459)3.16982325
47metaphase plate congression (GO:0051310)3.15856240
48regulation of telomere maintenance (GO:0032204)3.15625951
49motile cilium assembly (GO:0044458)3.15052781
50cell-cell recognition (GO:0009988)3.12821855
51pre-miRNA processing (GO:0031054)3.11761644
52ribonucleoprotein complex disassembly (GO:0032988)3.11434923
53mitotic nuclear envelope disassembly (GO:0007077)3.08036731
54regulation of nuclear cell cycle DNA replication (GO:0033262)3.07131663
55meiotic cell cycle (GO:0051321)3.06399807
56intra-S DNA damage checkpoint (GO:0031573)3.05945242
57attachment of spindle microtubules to kinetochore (GO:0008608)3.03759229
58epithelial cilium movement (GO:0003351)3.02256401
59substrate-independent telencephalic tangential interneuron migration (GO:0021843)3.02045324
60substrate-independent telencephalic tangential migration (GO:0021826)3.02045324
61retrograde transport, vesicle recycling within Golgi (GO:0000301)3.01313263
62regulation of action potential (GO:0098900)2.98735907
63epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)2.98517442
64spermatid development (GO:0007286)2.97883766
65mitotic sister chromatid segregation (GO:0000070)2.96684270
66establishment of chromosome localization (GO:0051303)2.96544291
67regulation of mitotic spindle checkpoint (GO:1903504)2.95791081
68regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)2.95791081
69protein localization to kinetochore (GO:0034501)2.93820301
70single strand break repair (GO:0000012)2.92514145
71organelle disassembly (GO:1903008)2.92448484
72DNA alkylation (GO:0006305)2.91712110
73DNA methylation (GO:0006306)2.91712110
74negative regulation of histone methylation (GO:0031061)2.90939677
75histone H3-K9 methylation (GO:0051567)2.89690939
76embryonic body morphogenesis (GO:0010172)2.88909464
77meiotic cell cycle process (GO:1903046)2.88702470
78forebrain neuron differentiation (GO:0021879)2.87907133
79head development (GO:0060322)2.87727189
80sister chromatid segregation (GO:0000819)2.86570309
81positive regulation of mitochondrial fission (GO:0090141)2.85937440
82histone exchange (GO:0043486)2.85550968
83tongue development (GO:0043586)2.85428602
84ATP-dependent chromatin remodeling (GO:0043044)2.85119958
85regulation of DNA endoreduplication (GO:0032875)2.85068292
86nuclear envelope disassembly (GO:0051081)2.85031892
87membrane disassembly (GO:0030397)2.85031892
88central nervous system projection neuron axonogenesis (GO:0021952)2.84957155
89presynaptic membrane assembly (GO:0097105)2.83589284
90poly(A)+ mRNA export from nucleus (GO:0016973)2.83533408
91negative regulation of telomere maintenance (GO:0032205)2.82046124
92presynaptic membrane organization (GO:0097090)2.80587617
93postsynaptic membrane organization (GO:0001941)2.79905349
94seminiferous tubule development (GO:0072520)2.79547534
95regulation of sarcomere organization (GO:0060297)2.78622415
96hindbrain development (GO:0030902)2.77620766
97axonal fasciculation (GO:0007413)2.74942305
98regulation of centriole replication (GO:0046599)2.74679330
99neural tube formation (GO:0001841)2.73606074
100chromosome segregation (GO:0007059)2.72760554
101protein localization to Golgi apparatus (GO:0034067)2.71496565
102microtubule polymerization or depolymerization (GO:0031109)2.71163596
103limb bud formation (GO:0060174)2.70752890
104resolution of meiotic recombination intermediates (GO:0000712)2.70662836
105regulation of RNA export from nucleus (GO:0046831)2.70439253
106mRNA splice site selection (GO:0006376)2.68992692
107meiosis I (GO:0007127)2.68427016
108intraciliary transport (GO:0042073)2.67537860
109regulation of spindle checkpoint (GO:0090231)2.67531176
110establishment of mitochondrion localization (GO:0051654)2.67509240
111transmission of nerve impulse (GO:0019226)2.66516085
112dendritic spine morphogenesis (GO:0060997)2.65879717
113peptidyl-lysine trimethylation (GO:0018023)2.65650248
114regulation of inhibitory postsynaptic membrane potential (GO:0060080)2.65599721
115DNA double-strand break processing (GO:0000729)2.65076386
116regulation of histone H3-K9 methylation (GO:0051570)2.63085579
117DNA replication-independent nucleosome organization (GO:0034724)2.62848329
118DNA replication-independent nucleosome assembly (GO:0006336)2.62848329
119cilium movement (GO:0003341)2.62749607
120regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450912.61776014
121DNA synthesis involved in DNA repair (GO:0000731)2.61735837
122axoneme assembly (GO:0035082)2.61255201
123central nervous system neuron axonogenesis (GO:0021955)2.60850401
124replication fork processing (GO:0031297)2.59296995
125spinal cord development (GO:0021510)2.58984956
126protein localization to chromosome (GO:0034502)2.58968862
127negative regulation of translation, ncRNA-mediated (GO:0040033)2.58684013
128regulation of translation, ncRNA-mediated (GO:0045974)2.58684013
129negative regulation of translation involved in gene silencing by miRNA (GO:0035278)2.58684013
130cilium organization (GO:0044782)2.58188857
131cilium assembly (GO:0042384)2.57744245
132reciprocal meiotic recombination (GO:0007131)2.57715451
133reciprocal DNA recombination (GO:0035825)2.57715451
134DNA methylation or demethylation (GO:0044728)2.57261594
135body morphogenesis (GO:0010171)2.56133944
136regulation of chromosome segregation (GO:0051983)2.55642779
137mitotic chromosome condensation (GO:0007076)2.54938503
138nucleus organization (GO:0006997)2.54672305
139spindle checkpoint (GO:0031577)2.54272995
140protein K6-linked ubiquitination (GO:0085020)2.54256684
141chromatin remodeling at centromere (GO:0031055)2.53513304
142DNA packaging (GO:0006323)2.53016323
143acrosome reaction (GO:0007340)2.52958463
144detection of light stimulus involved in sensory perception (GO:0050962)2.52580230
145detection of light stimulus involved in visual perception (GO:0050908)2.52580230
146RNA localization (GO:0006403)2.52557316
147negative regulation of mitotic metaphase/anaphase transition (GO:0045841)2.52253729
148negative regulation of sister chromatid segregation (GO:0033046)2.52253729
149negative regulation of mitotic sister chromatid separation (GO:2000816)2.52253729
150negative regulation of mitotic sister chromatid segregation (GO:0033048)2.52253729
151regulation of mitotic metaphase/anaphase transition (GO:0030071)2.51711866
152regulation of double-strand break repair via homologous recombination (GO:0010569)2.51630735
153negative regulation of chromosome segregation (GO:0051985)2.51619096
154synapsis (GO:0007129)2.51100048
155histone H2A monoubiquitination (GO:0035518)2.50560564
156negative regulation of DNA-dependent DNA replication (GO:2000104)2.49853711
157regulation of double-strand break repair (GO:2000779)2.49143567
158peptidyl-lysine methylation (GO:0018022)2.49055732
159positive regulation of action potential (GO:0045760)2.47766875
160spindle assembly checkpoint (GO:0071173)2.47696402
161negative regulation of DNA binding (GO:0043392)2.46816289
162regulation of collateral sprouting (GO:0048670)2.46764596
163histone H3-K4 trimethylation (GO:0080182)2.46072572
164DNA replication checkpoint (GO:0000076)2.42177068
165protein-DNA complex disassembly (GO:0032986)2.41384742
166nucleosome disassembly (GO:0006337)2.41384742
167cardiovascular system development (GO:0072358)2.38890366
168urogenital system development (GO:0001655)2.38670667
169cilium morphogenesis (GO:0060271)2.37486288
170negative regulation of gene silencing (GO:0060969)2.36605466

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human7.92264979
2MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse5.54061760
3FOXM1_23109430_ChIP-Seq_U2OS_Human4.33735440
4VDR_22108803_ChIP-Seq_LS180_Human3.70170934
5E2F4_17652178_ChIP-ChIP_JURKAT_Human3.68932298
6TP63_19390658_ChIP-ChIP_HaCaT_Human3.41464842
7RBPJ_22232070_ChIP-Seq_NCS_Mouse3.38536325
8FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human3.33654674
9* KDM5B_21448134_ChIP-Seq_MESCs_Mouse2.86218083
10ZNF274_21170338_ChIP-Seq_K562_Hela2.80689186
11MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.42848550
12GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.41811579
13IGF1R_20145208_ChIP-Seq_DFB_Human2.40965427
14E2F1_21310950_ChIP-Seq_MCF-7_Human2.34371011
15BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse2.29070328
16SALL1_21062744_ChIP-ChIP_HESCs_Human2.28889414
17EGR1_19374776_ChIP-ChIP_THP-1_Human2.17878723
18NOTCH1_21737748_ChIP-Seq_TLL_Human2.17558049
19CTBP1_25329375_ChIP-Seq_LNCAP_Human2.01437932
20BMI1_23680149_ChIP-Seq_NPCS_Mouse1.95339161
21FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.94168290
22CTBP2_25329375_ChIP-Seq_LNCAP_Human1.90065447
23* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.85604351
24GBX2_23144817_ChIP-Seq_PC3_Human1.82593902
25HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.81412373
26EZH2_27304074_Chip-Seq_ESCs_Mouse1.77611078
27FLI1_27457419_Chip-Seq_LIVER_Mouse1.73983378
28ZFP57_27257070_Chip-Seq_ESCs_Mouse1.68590339
29IRF1_19129219_ChIP-ChIP_H3396_Human1.66286408
30HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.64254614
31* REST_21632747_ChIP-Seq_MESCs_Mouse1.64157871
32ER_23166858_ChIP-Seq_MCF-7_Human1.63604573
33P300_19829295_ChIP-Seq_ESCs_Human1.63444698
34TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.61699024
35* MYCN_18555785_ChIP-Seq_MESCs_Mouse1.59996853
36DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.58540592
37PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.55278566
38UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.54407556
39HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.54133598
40MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.48276433
41TAF15_26573619_Chip-Seq_HEK293_Human1.47654227
42JARID2_20064375_ChIP-Seq_MESCs_Mouse1.47073064
43IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.46657412
44CBP_20019798_ChIP-Seq_JUKART_Human1.46657412
45IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.46416558
46EZH2_22144423_ChIP-Seq_EOC_Human1.44170656
47MYC_18555785_ChIP-Seq_MESCs_Mouse1.42980596
48SMAD_19615063_ChIP-ChIP_OVARY_Human1.41690663
49CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.41344376
50EST1_17652178_ChIP-ChIP_JURKAT_Human1.39056040
51ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.37134121
52CIITA_25753668_ChIP-Seq_RAJI_Human1.36270812
53MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.35179081
54YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.32999901
55ELK1_19687146_ChIP-ChIP_HELA_Human1.31759916
56FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.27223087
57FUS_26573619_Chip-Seq_HEK293_Human1.26722310
58TOP2B_26459242_ChIP-Seq_MCF-7_Human1.25230229
59REST_18959480_ChIP-ChIP_MESCs_Mouse1.24922026
60STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.24140290
61* VDR_23849224_ChIP-Seq_CD4+_Human1.23032803
62AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.22107669
63SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.21849441
64* STAT3_23295773_ChIP-Seq_U87_Human1.20011425
65EZH2_27294783_Chip-Seq_ESCs_Mouse1.19339995
66IRF8_21731497_ChIP-ChIP_J774_Mouse1.18799663
67EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.18644106
68PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.18440542
69POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.18203676
70SMAD3_21741376_ChIP-Seq_EPCs_Human1.17489433
71PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.17353074
72PCGF2_27294783_Chip-Seq_ESCs_Mouse1.16985116
73STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.16668436
74AR_25329375_ChIP-Seq_VCAP_Human1.15814526
75RNF2_27304074_Chip-Seq_NSC_Mouse1.14767255
76EED_16625203_ChIP-ChIP_MESCs_Mouse1.14390758
77RUNX2_22187159_ChIP-Seq_PCA_Human1.14311457
78MYC_18940864_ChIP-ChIP_HL60_Human1.14263024
79SUZ12_27294783_Chip-Seq_ESCs_Mouse1.13587279
80RNF2_27304074_Chip-Seq_ESCs_Mouse1.13224086
81KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.12953073
82PADI4_21655091_ChIP-ChIP_MCF-7_Human1.12677048
83MYC_19030024_ChIP-ChIP_MESCs_Mouse1.12572407
84MYB_26560356_Chip-Seq_TH2_Human1.11970908
85TCF4_23295773_ChIP-Seq_U87_Human1.10944717
86TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.10545346
87CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.10102136
88* MYB_26560356_Chip-Seq_TH1_Human1.09678666
89SMAD3_21741376_ChIP-Seq_ESCs_Human1.09659374
90* SMAD4_21799915_ChIP-Seq_A2780_Human1.09464107
91CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.09405171
92NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.09334736
93EWS_26573619_Chip-Seq_HEK293_Human1.09107770
94RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.08812723
95* KLF5_20875108_ChIP-Seq_MESCs_Mouse1.07897275
96RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.06736950
97GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.06293422
98NR3C1_21868756_ChIP-Seq_MCF10A_Human1.06052432
99FOXP3_21729870_ChIP-Seq_TREG_Human1.05637317
100ETV2_25802403_ChIP-Seq_MESCs_Mouse1.05559245
101* CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.05065100
102PKCTHETA_26484144_Chip-Seq_BREAST_Human1.04701829
103PCGF2_27294783_Chip-Seq_NPCs_Mouse1.04442314
104* NELFA_20434984_ChIP-Seq_ESCs_Mouse1.04291540
105FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.03871211
106* PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.03796322
107NFE2_27457419_Chip-Seq_LIVER_Mouse1.03427064
108AR_21909140_ChIP-Seq_LNCAP_Human1.02975635
109CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.02831291
110BCAT_22108803_ChIP-Seq_LS180_Human1.02267468
111SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.01852878
112TP53_22573176_ChIP-Seq_HFKS_Human1.00267610
113* GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.00082334
114WDR5_24793694_ChIP-Seq_LNCAP_Human0.99778891
115JARID2_20075857_ChIP-Seq_MESCs_Mouse0.99074685
116XRN2_22483619_ChIP-Seq_HELA_Human0.98591847
117PIAS1_25552417_ChIP-Seq_VCAP_Human0.97825579
118STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse0.97718357
119E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.96203745
120SOX2_16153702_ChIP-ChIP_HESCs_Human0.96103222
121POU3F2_20337985_ChIP-ChIP_501MEL_Human0.95298004
122SMAD4_21741376_ChIP-Seq_EPCs_Human0.93849800
123STAT4_19710469_ChIP-ChIP_TH1__Mouse0.93762214
124KDM5A_27292631_Chip-Seq_BREAST_Human0.93034380
125MYC_22102868_ChIP-Seq_BL_Human0.92713965
126CEBPB_26923725_Chip-Seq_MESODERM_Mouse0.91558612
127POU5F1_16153702_ChIP-ChIP_HESCs_Human0.91532134
128SIN3B_21632747_ChIP-Seq_MESCs_Mouse0.91024306
129RING1B_27294783_Chip-Seq_NPCs_Mouse0.90980699
130MYC_19079543_ChIP-ChIP_MESCs_Mouse0.90894817
131SUZ12_27294783_Chip-Seq_NPCs_Mouse0.90859440
132TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.90065221
133NCOR_22424771_ChIP-Seq_293T_Human0.89681921
134IRF1_21803131_ChIP-Seq_MONOCYTES_Human0.89275314
135HCFC1_20581084_ChIP-Seq_MESCs_Mouse0.88850361
136RUNX1_26923725_Chip-Seq_HPCs_Mouse0.87131444
137AR_21572438_ChIP-Seq_LNCaP_Human0.87059960
138RNF2_18974828_ChIP-Seq_MESCs_Mouse0.86975863
139EZH2_18974828_ChIP-Seq_MESCs_Mouse0.86975863
140RING1B_27294783_Chip-Seq_ESCs_Mouse0.86016393
141RCOR3_21632747_ChIP-Seq_MESCs_Mouse0.85899393
142NANOG_18555785_Chip-Seq_ESCs_Mouse0.85008887
143MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.84847602
144GABP_17652178_ChIP-ChIP_JURKAT_Human0.84675816
145* HOXB7_26014856_ChIP-Seq_BT474_Human0.83855544
146TTF2_22483619_ChIP-Seq_HELA_Human0.83834106
147OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.83805274
148FOXA1_21572438_ChIP-Seq_LNCaP_Human0.83756338
149TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.83536659
150POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.81445853
151TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.81445853
152FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human0.81048149
153ZFP322A_24550733_ChIP-Seq_MESCs_Mouse0.80555884
154TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat0.79255632
155CBX2_27304074_Chip-Seq_ESCs_Mouse0.78728732
156SMARCD1_25818293_ChIP-Seq_ESCs_Mouse0.78158268
157* GABP_19822575_ChIP-Seq_HepG2_Human0.77973030
158DCP1A_22483619_ChIP-Seq_HELA_Human0.77902999
159KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse0.77514169
160CHD1_19587682_ChIP-ChIP_MESCs_Mouse0.77331488
161SOX9_26525672_Chip-Seq_HEART_Mouse0.76021424
162EZH2_27294783_Chip-Seq_NPCs_Mouse0.75619119
163E2F1_18555785_Chip-Seq_ESCs_Mouse0.74953340
164MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.73219081
165GATA1_26923725_Chip-Seq_HPCs_Mouse0.72663188
166NANOG_21062744_ChIP-ChIP_HESCs_Human0.71689534
167EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse0.71026721
168HOXB4_20404135_ChIP-ChIP_EML_Mouse0.70279353

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008057_abnormal_DNA_replication4.18445456
2MP0008877_abnormal_DNA_methylation3.89071987
3MP0010094_abnormal_chromosome_stability3.19949097
4MP0005410_abnormal_fertilization3.19820360
5MP0008058_abnormal_DNA_repair3.07855778
6MP0003111_abnormal_nucleus_morphology2.82367847
7MP0008007_abnormal_cellular_replicative2.78194082
8MP0003077_abnormal_cell_cycle2.57598226
9MP0000778_abnormal_nervous_system2.37943221
10MP0005499_abnormal_olfactory_system2.31301315
11MP0005394_taste/olfaction_phenotype2.31301315
12MP0006292_abnormal_olfactory_placode2.27587254
13MP0003693_abnormal_embryo_hatching2.26742708
14MP0003121_genomic_imprinting2.23053509
15MP0002210_abnormal_sex_determination2.18622723
16MP0001929_abnormal_gametogenesis2.17455533
17MP0003787_abnormal_imprinting2.07893695
18MP0003123_paternal_imprinting2.05429587
19MP0003880_abnormal_central_pattern2.04268387
20MP0003890_abnormal_embryonic-extraembry1.95254733
21MP0003698_abnormal_male_reproductive1.93091189
22MP0006276_abnormal_autonomic_nervous1.86794548
23MP0004957_abnormal_blastocyst_morpholog1.81318890
24MP0008995_early_reproductive_senescence1.76908536
25MP0001485_abnormal_pinna_reflex1.73092778
26MP0003786_premature_aging1.72611507
27MP0001529_abnormal_vocalization1.71248119
28MP0001145_abnormal_male_reproductive1.66822739
29MP0000569_abnormal_digit_pigmentation1.61856792
30MP0002396_abnormal_hematopoietic_system1.59310657
31MP0008932_abnormal_embryonic_tissue1.59136382
32MP0004142_abnormal_muscle_tone1.56540455
33MP0005076_abnormal_cell_differentiation1.55976370
34MP0004133_heterotaxia1.55067945
35MP0004808_abnormal_hematopoietic_stem1.53521020
36MP0000653_abnormal_sex_gland1.53410779
37MP0009379_abnormal_foot_pigmentation1.50653766
38MP0001984_abnormal_olfaction1.49467789
39MP0000427_abnormal_hair_cycle1.40054910
40MP0002653_abnormal_ependyma_morphology1.39729642
41MP0002822_catalepsy1.39409757
42MP0000350_abnormal_cell_proliferation1.37905849
43MP0003136_yellow_coat_color1.36735102
44MP0002282_abnormal_trachea_morphology1.35802933
45MP0003122_maternal_imprinting1.35121147
46MP0002928_abnormal_bile_duct1.34065008
47MP0000955_abnormal_spinal_cord1.32590103
48MP0002938_white_spotting1.31101145
49MP0003763_abnormal_thymus_physiology1.30341091
50MP0001502_abnormal_circadian_rhythm1.29428971
51MP0001730_embryonic_growth_arrest1.28787884
52MP0001672_abnormal_embryogenesis/_devel1.28333417
53MP0005380_embryogenesis_phenotype1.28333417
54MP0002557_abnormal_social/conspecific_i1.27678319
55MP0003283_abnormal_digestive_organ1.27541664
56MP0002234_abnormal_pharynx_morphology1.26488043
57MP0003938_abnormal_ear_development1.26348915
58MP0009053_abnormal_anal_canal1.26255619
59MP0001119_abnormal_female_reproductive1.25861431
60MP0002084_abnormal_developmental_patter1.22802021
61MP0003937_abnormal_limbs/digits/tail_de1.22132956
62MP0005551_abnormal_eye_electrophysiolog1.21846934
63MP0002272_abnormal_nervous_system1.21644407
64MP0003984_embryonic_growth_retardation1.21623189
65MP0003315_abnormal_perineum_morphology1.21203701
66MP0002161_abnormal_fertility/fecundity1.19894600
67MP0001486_abnormal_startle_reflex1.19756956
68MP0001293_anophthalmia1.19082595
69MP0002184_abnormal_innervation1.18825795
70MP0004197_abnormal_fetal_growth/weight/1.18598767
71MP0002085_abnormal_embryonic_tissue1.18453886
72MP0001697_abnormal_embryo_size1.18403357
73MP0002751_abnormal_autonomic_nervous1.17751427
74MP0003385_abnormal_body_wall1.17520611
75MP0000015_abnormal_ear_pigmentation1.17296664
76MP0002088_abnormal_embryonic_growth/wei1.16990121
77MP0003119_abnormal_digestive_system1.15645123
78MP0003943_abnormal_hepatobiliary_system1.15265999
79MP0008961_abnormal_basal_metabolism1.13717969
80MP0002572_abnormal_emotion/affect_behav1.11266677
81MP0004742_abnormal_vestibular_system1.11206342
82MP0002063_abnormal_learning/memory/cond1.10672860
83MP0000703_abnormal_thymus_morphology1.09526805
84MP0009745_abnormal_behavioral_response1.08367449
85MP0005389_reproductive_system_phenotype1.05791407
86MP0002160_abnormal_reproductive_system1.05438524
87MP0005671_abnormal_response_to1.05165186
88MP0000432_abnormal_head_morphology1.05115487
89MP0002752_abnormal_somatic_nervous1.04040819
90MP0009046_muscle_twitch1.03911680
91MP0005423_abnormal_somatic_nervous1.03398088
92MP0002398_abnormal_bone_marrow1.01995129
93MP0002152_abnormal_brain_morphology1.01439597
94MP0003115_abnormal_respiratory_system1.00789124
95MP0002882_abnormal_neuron_morphology1.00756210
96MP0000049_abnormal_middle_ear1.00542132
97MP0002067_abnormal_sensory_capabilities1.00187974
98MP0000026_abnormal_inner_ear1.00113583
99MP0002086_abnormal_extraembryonic_tissu0.99828893
100MP0002095_abnormal_skin_pigmentation0.99772668
101MP0003942_abnormal_urinary_system0.99462887
102MP0002249_abnormal_larynx_morphology0.99047143
103MP0001919_abnormal_reproductive_system0.97955155
104MP0002638_abnormal_pupillary_reflex0.96160076
105MP0001968_abnormal_touch/_nociception0.95905530
106MP0002116_abnormal_craniofacial_bone0.94763162
107MP0010307_abnormal_tumor_latency0.94023542
108MP0003755_abnormal_palate_morphology0.94002575
109MP0003861_abnormal_nervous_system0.93455867
110MP0003935_abnormal_craniofacial_develop0.93276473
111MP0003635_abnormal_synaptic_transmissio0.93226562
112MP0000313_abnormal_cell_death0.93100819
113MP0002877_abnormal_melanocyte_morpholog0.92633104
114MP0000631_abnormal_neuroendocrine_gland0.91840001
115MP0000537_abnormal_urethra_morphology0.91253338
116MP0000428_abnormal_craniofacial_morphol0.90820005
117MP0000516_abnormal_urinary_system0.89368065
118MP0005367_renal/urinary_system_phenotyp0.89368065
119MP0005391_vision/eye_phenotype0.89101943
120MP0005174_abnormal_tail_pigmentation0.88229089
121MP0002092_abnormal_eye_morphology0.87937316
122MP0005377_hearing/vestibular/ear_phenot0.87445530
123MP0003878_abnormal_ear_physiology0.87445530
124MP0001286_abnormal_eye_development0.85907521
125MP0002735_abnormal_chemical_nociception0.85737921
126MP0000647_abnormal_sebaceous_gland0.85496792
127MP0004811_abnormal_neuron_physiology0.84626303
128MP0002734_abnormal_mechanical_nocicepti0.84125553
129MP0002080_prenatal_lethality0.83874148
130MP0005195_abnormal_posterior_eye0.83694243
131MP0002109_abnormal_limb_morphology0.83429031
132MP0001970_abnormal_pain_threshold0.82553453
133MP0000566_synostosis0.82530030
134MP0004924_abnormal_behavior0.82511843
135MP0005386_behavior/neurological_phenoty0.82511843
136MP0002102_abnormal_ear_morphology0.82379399
137MP0001915_intracranial_hemorrhage0.82298377
138MP0003567_abnormal_fetal_cardiomyocyte0.82250491
139MP0010030_abnormal_orbit_morphology0.80804771
140MP0004885_abnormal_endolymph0.75106534
141MP0009703_decreased_birth_body0.74912749
142MP0005397_hematopoietic_system_phenotyp0.74169421
143MP0001545_abnormal_hematopoietic_system0.74169421
144MP0002114_abnormal_axial_skeleton0.73715104
145MP0002019_abnormal_tumor_incidence0.73550830
146MP0009672_abnormal_birth_weight0.71787786
147MP0002163_abnormal_gland_morphology0.71464208
148MP0009250_abnormal_appendicular_skeleto0.70240776
149MP0002233_abnormal_nose_morphology0.69908684
150MP0002925_abnormal_cardiovascular_devel0.69212062
151MP0002177_abnormal_outer_ear0.68342715
152MP0003699_abnormal_female_reproductive0.68187759
153MP0008789_abnormal_olfactory_epithelium0.67321945
154MP0009333_abnormal_splenocyte_physiolog0.66449444
155MP0001188_hyperpigmentation0.66209194
156MP0001835_abnormal_antigen_presentation0.66061966

Predicted human phenotypes

RankGene SetZ-score
1Respiratory insufficiency due to defective ciliary clearance (HP:0200073)4.68200253
2Absent/shortened dynein arms (HP:0200106)3.88744031
3Dynein arm defect of respiratory motile cilia (HP:0012255)3.88744031
4Pancreatic fibrosis (HP:0100732)3.53827296
5Chronic hepatic failure (HP:0100626)3.53474196
6Pancreatic cysts (HP:0001737)3.29185180
7Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)3.20848219
8Short 4th metacarpal (HP:0010044)3.20848219
9Medial flaring of the eyebrow (HP:0010747)3.12715003
10Progressive cerebellar ataxia (HP:0002073)3.12708561
11Papillary thyroid carcinoma (HP:0002895)3.10703275
12Abnormal respiratory epithelium morphology (HP:0012253)3.06072566
13Abnormal respiratory motile cilium morphology (HP:0005938)3.06072566
14Gait imbalance (HP:0002141)3.04619200
15Abnormal respiratory motile cilium physiology (HP:0012261)3.00694639
16Rhinitis (HP:0012384)2.89931933
17Congenital primary aphakia (HP:0007707)2.85131306
18Ectopic kidney (HP:0000086)2.80629796
19Volvulus (HP:0002580)2.73975209
20Abnormality of the fingertips (HP:0001211)2.70783671
21Poor coordination (HP:0002370)2.68422610
22Nephrogenic diabetes insipidus (HP:0009806)2.60522816
23Abnormal number of incisors (HP:0011064)2.60352914
24Chromsome breakage (HP:0040012)2.52323254
25Chromosomal breakage induced by crosslinking agents (HP:0003221)2.46532111
26Abnormal ciliary motility (HP:0012262)2.45755911
27Abnormality of DNA repair (HP:0003254)2.45529620
28Abnormal drinking behavior (HP:0030082)2.45230299
29Polydipsia (HP:0001959)2.45230299
30Anencephaly (HP:0002323)2.44714484
31Nephroblastoma (Wilms tumor) (HP:0002667)2.42760914
3211 pairs of ribs (HP:0000878)2.36366447
33Sclerocornea (HP:0000647)2.36316002
34Drooling (HP:0002307)2.33633152
35Bony spicule pigmentary retinopathy (HP:0007737)2.32687273
36Genital tract atresia (HP:0001827)2.31735294
37Rib fusion (HP:0000902)2.30994482
38Cystic liver disease (HP:0006706)2.30365085
39Impulsivity (HP:0100710)2.30242043
40Medulloblastoma (HP:0002885)2.27173468
41Vaginal atresia (HP:0000148)2.26050887
42Oligodactyly (hands) (HP:0001180)2.25673435
43Embryonal renal neoplasm (HP:0011794)2.25179199
44Hypoplastic iliac wings (HP:0002866)2.24315112
45Thyroid-stimulating hormone excess (HP:0002925)2.22073655
46Nephronophthisis (HP:0000090)2.21495931
47Long eyelashes (HP:0000527)2.20676555
48Trigonocephaly (HP:0000243)2.20221273
49Patellar aplasia (HP:0006443)2.17194567
50Abnormality of the renal cortex (HP:0011035)2.15683096
51Tubulointerstitial nephritis (HP:0001970)2.15117528
52Abnormality of the 4th metacarpal (HP:0010012)2.13037214
53Facial hemangioma (HP:0000329)2.12804330
54Abnormal spermatogenesis (HP:0008669)2.12297338
55Abnormal hair whorl (HP:0010721)2.11474311
56Abnormality of the phalanges of the hallux (HP:0010057)2.11072271
57Excessive salivation (HP:0003781)2.10999676
58Supernumerary spleens (HP:0009799)2.10409076
59Aplasia/Hypoplasia of the sternum (HP:0006714)2.09434764
60Absent frontal sinuses (HP:0002688)2.09121063
61Birth length less than 3rd percentile (HP:0003561)2.08321578
62Hyperventilation (HP:0002883)2.04783939
63Anophthalmia (HP:0000528)2.04469314
64Dislocated radial head (HP:0003083)2.02351380
65Deep philtrum (HP:0002002)2.02270187
66Abnormal lung lobation (HP:0002101)2.02180581
67Tubular atrophy (HP:0000092)2.01375147
68Aplasia/Hypoplasia of the tongue (HP:0010295)2.01142816
69Degeneration of anterior horn cells (HP:0002398)2.00745801
70Abnormality of the anterior horn cell (HP:0006802)2.00745801
71Abnormality of the aortic arch (HP:0012303)1.99986227
72Bronchiectasis (HP:0002110)1.99423125
73Type II lissencephaly (HP:0007260)1.98253900
74Protruding tongue (HP:0010808)1.98203848
75Ependymoma (HP:0002888)1.98025953
76Colon cancer (HP:0003003)1.98004502
77Aplasia/Hypoplasia of the patella (HP:0006498)1.97147296
78Pendular nystagmus (HP:0012043)1.96505628
79Congenital stationary night blindness (HP:0007642)1.96425987
80Shawl scrotum (HP:0000049)1.95661346
81Lissencephaly (HP:0001339)1.94058944
82Abnormality of the radial head (HP:0003995)1.94054586
83Chronic bronchitis (HP:0004469)1.92994402
84Small hand (HP:0200055)1.92861539
85Fibular hypoplasia (HP:0003038)1.91820743
86Acute lymphatic leukemia (HP:0006721)1.90794627
87Thyroid carcinoma (HP:0002890)1.90523534
88Abnormality of the nasal septum (HP:0000419)1.89724551
89Specific learning disability (HP:0001328)1.89344243
90Pachygyria (HP:0001302)1.89271779
91Postaxial hand polydactyly (HP:0001162)1.89120345
92Bronchitis (HP:0012387)1.88666412
93Abnormality of chromosome stability (HP:0003220)1.88611443
94Narrow forehead (HP:0000341)1.88449342
95Abnormal biliary tract physiology (HP:0012439)1.87636853
96Bile duct proliferation (HP:0001408)1.87636853
97Meckel diverticulum (HP:0002245)1.86837289
98Broad-based gait (HP:0002136)1.86836928
99Polyphagia (HP:0002591)1.86604167
100Recurrent bronchitis (HP:0002837)1.85781085
101Oligodactyly (HP:0012165)1.85427313
102Abnormality of the renal medulla (HP:0100957)1.85405862
103High anterior hairline (HP:0009890)1.85146054
104Astigmatism (HP:0000483)1.84413264
105Congenital hepatic fibrosis (HP:0002612)1.84163646
106Broad palm (HP:0001169)1.84157804
107Abnormality of the metopic suture (HP:0005556)1.83848760
108Midline defect of the nose (HP:0004122)1.83768870
109Short ribs (HP:0000773)1.83114508
110Increased nuchal translucency (HP:0010880)1.83067102
111Postaxial foot polydactyly (HP:0001830)1.81286360
112Occipital encephalocele (HP:0002085)1.81102034
113Hip dysplasia (HP:0001385)1.80548369
114Genetic anticipation (HP:0003743)1.79900046
115Broad phalanges of the hand (HP:0009768)1.79196066
116Abnormality of the intervertebral disk (HP:0005108)1.77982527
117Exotropia (HP:0000577)1.76751482
118Infertility (HP:0000789)1.76053206
119Abnormality of the labia minora (HP:0012880)1.75870437
120Abnormality of midbrain morphology (HP:0002418)1.75296493
121Molar tooth sign on MRI (HP:0002419)1.75296493
122Abnormality of chromosome segregation (HP:0002916)1.75278888
123Syringomyelia (HP:0003396)1.75212547
124Spinal cord lesions (HP:0100561)1.75212547
125Septo-optic dysplasia (HP:0100842)1.75022099
126Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)1.74499833
127Cerebellar dysplasia (HP:0007033)1.74007867
128Dandy-Walker malformation (HP:0001305)1.73798100
129Aplasia/Hypoplasia of the uvula (HP:0010293)1.73577754
130Azoospermia (HP:0000027)1.73441912
131Abnormal rod and cone electroretinograms (HP:0008323)1.73342492
132Highly arched eyebrow (HP:0002553)1.73187391
133Aganglionic megacolon (HP:0002251)1.73064764
134Renal dysplasia (HP:0000110)1.72621204
135Polyuria (HP:0000103)1.71834564
136Abnormality of the ileum (HP:0001549)1.71786365
137Holoprosencephaly (HP:0001360)1.71248601
138Facial cleft (HP:0002006)1.70907964
139Reticulocytopenia (HP:0001896)1.70852523
140Esophageal atresia (HP:0002032)1.69072875
141Broad thumb (HP:0011304)1.68620584
142Acute myeloid leukemia (HP:0004808)1.68389238
143Adrenal hypoplasia (HP:0000835)1.67456364
144Broad finger (HP:0001500)1.67424273
145Deviation of the thumb (HP:0009603)1.66796505
146Prominent nasal bridge (HP:0000426)1.66388510
147True hermaphroditism (HP:0010459)1.65659314
148Nasal polyposis (HP:0100582)1.65172609
149Multicystic kidney dysplasia (HP:0000003)1.65172485
150Absent speech (HP:0001344)1.64559806
151Broad phalanx (HP:0006009)1.64534294
152Vitreoretinal degeneration (HP:0000655)1.64385476
153Tubulointerstitial abnormality (HP:0001969)1.64299740
154Myelodysplasia (HP:0002863)1.64192325
155Optic nerve hypoplasia (HP:0000609)1.64135236
156Optic nerve coloboma (HP:0000588)1.62045302
157Epileptic encephalopathy (HP:0200134)1.60887026
158Long clavicles (HP:0000890)1.59498792
159Abnormality of incisor morphology (HP:0011063)1.59131090
160Microglossia (HP:0000171)1.57529019
161Flat capital femoral epiphysis (HP:0003370)1.57331823
162Hypoplastic pelvis (HP:0008839)1.56555935
163Truncal obesity (HP:0001956)1.56192049
164Abnormality of the incisor (HP:0000676)1.55772083
165Cleft eyelid (HP:0000625)1.55613782
166Preaxial hand polydactyly (HP:0001177)1.55302864
167Proximal placement of thumb (HP:0009623)1.53420529
168Irregular epiphyses (HP:0010582)1.52927086
169Rhabdomyosarcoma (HP:0002859)1.52679654
170Abnormality of the distal phalanx of the thumb (HP:0009617)1.51829513
171Prominent metopic ridge (HP:0005487)1.51091764
172Small intestinal stenosis (HP:0012848)1.50386862
173Duodenal stenosis (HP:0100867)1.50386862

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CDC73.72097392
2CDK123.31304371
3SRPK13.04870872
4PRKD32.96127383
5TRIM282.66993685
6STK38L2.63607515
7CASK2.63393928
8BMPR1B2.59179581
9FRK2.51878144
10TNIK2.38245645
11MKNK22.35134173
12TXK2.33721011
13NEK22.25095093
14PLK42.09367302
15CAMK1G2.02977180
16NTRK21.99769701
17TESK11.98434227
18MARK11.94310916
19MKNK11.93029026
20BUB11.89957232
21BRSK21.89405537
22STK241.86854503
23PLK31.85810414
24AKT31.85040292
25PDK41.84612474
26PDK31.84612474
27SIK31.78615997
28ERBB31.78421986
29STK31.74380250
30SIK21.71617886
31TLK11.66607146
32EPHB21.65967394
33ACVR1B1.62760866
34ATR1.59237121
35BRD41.55746007
36LATS11.55726882
37CDK191.52734074
38MAP4K21.51974331
39CHEK11.45512115
40CCNB11.45193470
41PASK1.44861816
42STK161.43877933
43PLK11.41215589
44WNK41.41010079
45MAPK131.39916256
46BMPR21.34231469
47MAPK151.32563667
48CAMK1D1.32065041
49ATM1.31854111
50CHEK21.29435501
51VRK11.22889763
52EPHA41.22401519
53WEE11.22344066
54PINK11.16610031
55DMPK1.12383606
56ICK1.11841273
57STK101.10922479
58PLK21.10725579
59MARK31.10400444
60NEK61.09748846
61MELK1.07990617
62MAP3K141.07870002
63CDK71.06153331
64PIK3CA1.03746257
65NUAK11.01940524
66PDK21.00855537
67CHUK1.00348321
68JAK30.99816287
69EIF2AK20.95640552
70MAP3K100.94909542
71CDK20.94157488
72TTK0.93508940
73CDK40.91788937
74INSRR0.91049677
75CSNK1G20.90513972
76TYRO30.90384644
77CDK80.90107933
78FGFR20.89157088
79STK110.88211625
80PKN10.86540880
81ADRBK20.86068167
82MAP3K60.85298560
83CLK10.84125452
84DYRK20.83634834
85IRAK10.83054706
86LATS20.82562812
87DYRK30.82165670
88BRSK10.81778858
89PRKCG0.81327184
90MAP3K90.80361659
91AURKB0.79730394
92PIM10.77634952
93MINK10.77323714
94MUSK0.77175423
95CDK10.76113529
96YES10.75690974
97CAMK10.74030874
98ZAK0.73744888
99BCR0.71869544
100SGK20.70943893
101RPS6KA40.68875161
102OXSR10.66572798
103TSSK60.66065730
104IRAK20.65145970
105MAPKAPK50.65027806
106CDK30.63214539
107CSNK1A1L0.62805868
108MAP4K10.62717882
109BCKDK0.62425581
110RPS6KB10.62315334
111CDK90.61762232
112STK390.61712933
113IKBKE0.61615598
114MTOR0.60759547
115CAMK40.59884693
116MAP2K70.59501375
117CSNK1G10.57558049
118SGK2230.57440727
119SGK4940.57440727
120CSNK1G30.57055248
121PAK30.56676539
122CSNK1E0.56238179
123PNCK0.55607882
124PBK0.54317322
125CAMKK20.53974829
126MAPK140.53735068
127FGFR30.53233592
128MARK20.53172753
129PRKCZ0.53124174
130MAP3K50.52831770
131UHMK10.52154523
132BRAF0.51399776
133MAP3K70.50907381
134PTK2B0.49963519
135ZAP700.48687139
136PRKAA10.47570181
137DYRK1B0.47520856
138DYRK1A0.46476118
139NTRK30.44654319
140GSK3B0.43781367
141MAP2K20.43285395
142NLK0.43113765
143RPS6KA60.42942513
144MAP3K40.42730321
145KSR10.42289244
146EIF2AK10.40309079
147CSNK1D0.38689754
148AURKA0.37102168
149SGK30.36586456
150MAPK10.34217609
151PRKDC0.33705485
152AKT10.32834422
153WNK30.30651031

Predicted pathways (KEGG)

RankGene SetZ-score
1Homologous recombination_Homo sapiens_hsa034403.05915154
2Basal transcription factors_Homo sapiens_hsa030222.79909913
3Fanconi anemia pathway_Homo sapiens_hsa034602.72626589
4Phototransduction_Homo sapiens_hsa047442.69271879
5Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.64024750
6Nicotine addiction_Homo sapiens_hsa050332.62034478
7Cell cycle_Homo sapiens_hsa041102.59397978
8DNA replication_Homo sapiens_hsa030302.53399917
9Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.50119953
10RNA transport_Homo sapiens_hsa030132.34105584
11Mismatch repair_Homo sapiens_hsa034302.28522214
12Spliceosome_Homo sapiens_hsa030402.26572372
13mRNA surveillance pathway_Homo sapiens_hsa030152.24987107
14Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.24835768
15RNA degradation_Homo sapiens_hsa030182.21010045
16Terpenoid backbone biosynthesis_Homo sapiens_hsa009002.00386198
17Selenocompound metabolism_Homo sapiens_hsa004501.99885208
18Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.91595924
19RNA polymerase_Homo sapiens_hsa030201.88826975
20Nucleotide excision repair_Homo sapiens_hsa034201.85265813
21Base excision repair_Homo sapiens_hsa034101.84068397
22Protein export_Homo sapiens_hsa030601.72586388
23Linoleic acid metabolism_Homo sapiens_hsa005911.68927806
24Non-homologous end-joining_Homo sapiens_hsa034501.59533768
25Herpes simplex infection_Homo sapiens_hsa051681.57881927
26alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.57165872
27Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.55743175
28Morphine addiction_Homo sapiens_hsa050321.47502162
29Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.47462957
30Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.42263215
31Oocyte meiosis_Homo sapiens_hsa041141.36412672
32Circadian rhythm_Homo sapiens_hsa047101.31799338
33Ether lipid metabolism_Homo sapiens_hsa005651.21095986
34NF-kappa B signaling pathway_Homo sapiens_hsa040641.20741674
35Ribosome_Homo sapiens_hsa030101.20415213
36p53 signaling pathway_Homo sapiens_hsa041151.19897659
37Regulation of autophagy_Homo sapiens_hsa041401.18872877
38Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.18687849
39Epstein-Barr virus infection_Homo sapiens_hsa051691.17226208
40HTLV-I infection_Homo sapiens_hsa051661.16160328
41Butanoate metabolism_Homo sapiens_hsa006501.15881130
42Dorso-ventral axis formation_Homo sapiens_hsa043201.15301263
43MicroRNAs in cancer_Homo sapiens_hsa052061.13685165
44Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.13578931
45Proteasome_Homo sapiens_hsa030501.12591455
46Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.12505685
47Measles_Homo sapiens_hsa051621.11687681
48TGF-beta signaling pathway_Homo sapiens_hsa043501.11679639
49Pyrimidine metabolism_Homo sapiens_hsa002401.10926297
50Steroid biosynthesis_Homo sapiens_hsa001001.09847642
51Cardiac muscle contraction_Homo sapiens_hsa042601.09495678
52Glutamatergic synapse_Homo sapiens_hsa047241.08603175
53Olfactory transduction_Homo sapiens_hsa047401.08278353
54Huntingtons disease_Homo sapiens_hsa050161.07860160
55GABAergic synapse_Homo sapiens_hsa047271.07713169
56Transcriptional misregulation in cancer_Homo sapiens_hsa052021.06293525
57One carbon pool by folate_Homo sapiens_hsa006701.05806196
58Sulfur relay system_Homo sapiens_hsa041221.05577791
59Basal cell carcinoma_Homo sapiens_hsa052171.03374351
60Cocaine addiction_Homo sapiens_hsa050301.03135580
61Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.02965362
62Primary immunodeficiency_Homo sapiens_hsa053401.02208375
63Hippo signaling pathway_Homo sapiens_hsa043901.01905178
64Cholinergic synapse_Homo sapiens_hsa047251.01665161
65Influenza A_Homo sapiens_hsa051641.01066491
66Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.00943395
67Hepatitis B_Homo sapiens_hsa051610.99905029
68Circadian entrainment_Homo sapiens_hsa047130.98022239
69Wnt signaling pathway_Homo sapiens_hsa043100.95589588
70Serotonergic synapse_Homo sapiens_hsa047260.94892669
71Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.94171258
72Viral carcinogenesis_Homo sapiens_hsa052030.93537836
73Taste transduction_Homo sapiens_hsa047420.92317906
74Antigen processing and presentation_Homo sapiens_hsa046120.91368979
75Colorectal cancer_Homo sapiens_hsa052100.91264760
76Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.90894236
77Parkinsons disease_Homo sapiens_hsa050120.90002970
78Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.87688087
79Notch signaling pathway_Homo sapiens_hsa043300.85938374
80Oxidative phosphorylation_Homo sapiens_hsa001900.85824183
81T cell receptor signaling pathway_Homo sapiens_hsa046600.85697216
82Type I diabetes mellitus_Homo sapiens_hsa049400.85615785
83Purine metabolism_Homo sapiens_hsa002300.85551566
84Allograft rejection_Homo sapiens_hsa053300.83608554
85Propanoate metabolism_Homo sapiens_hsa006400.83089271
86cAMP signaling pathway_Homo sapiens_hsa040240.82396041
87Graft-versus-host disease_Homo sapiens_hsa053320.82331465
88Dopaminergic synapse_Homo sapiens_hsa047280.81868644
89Adherens junction_Homo sapiens_hsa045200.81474070
90Long-term depression_Homo sapiens_hsa047300.79428172
91Intestinal immune network for IgA production_Homo sapiens_hsa046720.75745878
92Chronic myeloid leukemia_Homo sapiens_hsa052200.75574350
93Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.75317787
94Hedgehog signaling pathway_Homo sapiens_hsa043400.74975200
95Jak-STAT signaling pathway_Homo sapiens_hsa046300.74960237
96Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.72622152
97Thyroid cancer_Homo sapiens_hsa052160.72592275
98Prostate cancer_Homo sapiens_hsa052150.72398738
99Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.70865207
100Small cell lung cancer_Homo sapiens_hsa052220.69019825
101Thyroid hormone signaling pathway_Homo sapiens_hsa049190.68615869
102Pancreatic cancer_Homo sapiens_hsa052120.67053277
103Insulin secretion_Homo sapiens_hsa049110.65416933
104Leishmaniasis_Homo sapiens_hsa051400.63934543
105Nitrogen metabolism_Homo sapiens_hsa009100.63424264
106Viral myocarditis_Homo sapiens_hsa054160.62751341
107FoxO signaling pathway_Homo sapiens_hsa040680.62031809
108Type II diabetes mellitus_Homo sapiens_hsa049300.61426008
109RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.60446227
110TNF signaling pathway_Homo sapiens_hsa046680.60390693
111ABC transporters_Homo sapiens_hsa020100.60186560
112Lysine degradation_Homo sapiens_hsa003100.60061048
113Tryptophan metabolism_Homo sapiens_hsa003800.58906828
114N-Glycan biosynthesis_Homo sapiens_hsa005100.57115683
115Oxytocin signaling pathway_Homo sapiens_hsa049210.56678545
116Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.56301004
117Toll-like receptor signaling pathway_Homo sapiens_hsa046200.56265333
118Apoptosis_Homo sapiens_hsa042100.56107213
119Prolactin signaling pathway_Homo sapiens_hsa049170.54511230
120Pathways in cancer_Homo sapiens_hsa052000.54190895
121Endometrial cancer_Homo sapiens_hsa052130.54182005
122Osteoclast differentiation_Homo sapiens_hsa043800.54154125
123NOD-like receptor signaling pathway_Homo sapiens_hsa046210.52856258
124B cell receptor signaling pathway_Homo sapiens_hsa046620.52390791
125Melanoma_Homo sapiens_hsa052180.52371372
126MAPK signaling pathway_Homo sapiens_hsa040100.52359082
127Neurotrophin signaling pathway_Homo sapiens_hsa047220.51753209
128Toxoplasmosis_Homo sapiens_hsa051450.51039391
129Acute myeloid leukemia_Homo sapiens_hsa052210.49862351
130Alcoholism_Homo sapiens_hsa050340.49217809
131Autoimmune thyroid disease_Homo sapiens_hsa053200.49183573
132mTOR signaling pathway_Homo sapiens_hsa041500.47904987
133Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.47345556
134Legionellosis_Homo sapiens_hsa051340.47010502
135Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.45819503
136Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.45396829
137Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.45382927
138Glycerolipid metabolism_Homo sapiens_hsa005610.44050594
139Melanogenesis_Homo sapiens_hsa049160.42607957
140ErbB signaling pathway_Homo sapiens_hsa040120.41916156
141beta-Alanine metabolism_Homo sapiens_hsa004100.40968254
142Chemokine signaling pathway_Homo sapiens_hsa040620.40579216
143AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.40012934
144Long-term potentiation_Homo sapiens_hsa047200.39426530
145Glucagon signaling pathway_Homo sapiens_hsa049220.38841102
146Glycerophospholipid metabolism_Homo sapiens_hsa005640.38664169
147Hematopoietic cell lineage_Homo sapiens_hsa046400.37986135
148Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.37824139
149Axon guidance_Homo sapiens_hsa043600.37660122
150Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.37557249
151Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.37211741
152Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.36210386
153Longevity regulating pathway - mammal_Homo sapiens_hsa042110.36007201
154Ras signaling pathway_Homo sapiens_hsa040140.35951541
155Shigellosis_Homo sapiens_hsa051310.35524360
156Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.35291908
157Amphetamine addiction_Homo sapiens_hsa050310.34583197

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