Rank | Gene Set | Z-score |
---|---|---|
1 | nuclear pore complex assembly (GO:0051292) | 6.59474415 |
2 | nuclear pore organization (GO:0006999) | 6.37188474 |
3 | mitotic sister chromatid cohesion (GO:0007064) | 5.20281012 |
4 | pre-miRNA processing (GO:0031054) | 5.00143871 |
5 | negative regulation of histone methylation (GO:0031061) | 4.94019309 |
6 | pore complex assembly (GO:0046931) | 4.77825382 |
7 | regulation of histone H3-K9 methylation (GO:0051570) | 4.75450501 |
8 | protein localization to kinetochore (GO:0034501) | 4.65269350 |
9 | mitotic chromosome condensation (GO:0007076) | 4.48598679 |
10 | mitotic nuclear envelope disassembly (GO:0007077) | 4.41624850 |
11 | regulation of RNA export from nucleus (GO:0046831) | 4.31725997 |
12 | histone H3-K36 demethylation (GO:0070544) | 4.27166705 |
13 | nuclear envelope disassembly (GO:0051081) | 4.25023594 |
14 | membrane disassembly (GO:0030397) | 4.25023594 |
15 | regulation of histone H3-K27 methylation (GO:0061085) | 4.24329533 |
16 | DNA unwinding involved in DNA replication (GO:0006268) | 4.22130850 |
17 | sister chromatid segregation (GO:0000819) | 4.18570202 |
18 | positive regulation of chromosome segregation (GO:0051984) | 4.17174588 |
19 | positive regulation of mitotic sister chromatid separation (GO:1901970) | 4.16949719 |
20 | positive regulation of mitotic metaphase/anaphase transition (GO:0045842) | 4.16949719 |
21 | positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101) | 4.16949719 |
22 | protein localization to chromosome, centromeric region (GO:0071459) | 4.16612544 |
23 | regulation of posttranscriptional gene silencing (GO:0060147) | 4.10233635 |
24 | regulation of gene silencing by miRNA (GO:0060964) | 4.10233635 |
25 | regulation of gene silencing by RNA (GO:0060966) | 4.10233635 |
26 | DNA replication-dependent nucleosome organization (GO:0034723) | 4.09734221 |
27 | DNA replication-dependent nucleosome assembly (GO:0006335) | 4.09734221 |
28 | regulation of attachment of spindle microtubules to kinetochore (GO:0051988) | 4.04926097 |
29 | mitotic sister chromatid segregation (GO:0000070) | 3.99975749 |
30 | heterochromatin organization (GO:0070828) | 3.98820294 |
31 | monoubiquitinated protein deubiquitination (GO:0035520) | 3.95602103 |
32 | DNA geometric change (GO:0032392) | 3.85200913 |
33 | DNA duplex unwinding (GO:0032508) | 3.84010051 |
34 | mitotic metaphase plate congression (GO:0007080) | 3.82993640 |
35 | regulation of sister chromatid cohesion (GO:0007063) | 3.82768282 |
36 | DNA topological change (GO:0006265) | 3.82172882 |
37 | chromatin assembly (GO:0031497) | 3.75537013 |
38 | histone H2A monoubiquitination (GO:0035518) | 3.75019596 |
39 | regulation of centriole replication (GO:0046599) | 3.72223863 |
40 | regulation of spindle organization (GO:0090224) | 3.69827655 |
41 | regulation of translational termination (GO:0006449) | 3.65244912 |
42 | negative regulation of mRNA splicing, via spliceosome (GO:0048025) | 3.58097103 |
43 | dosage compensation (GO:0007549) | 3.55610989 |
44 | regulation of mitotic spindle organization (GO:0060236) | 3.54557164 |
45 | regulation of helicase activity (GO:0051095) | 3.54018946 |
46 | metaphase plate congression (GO:0051310) | 3.51976128 |
47 | regulation of nucleobase-containing compound transport (GO:0032239) | 3.48623882 |
48 | folic acid-containing compound biosynthetic process (GO:0009396) | 3.44649176 |
49 | histone lysine demethylation (GO:0070076) | 3.41903533 |
50 | somatic diversification of immune receptors via somatic mutation (GO:0002566) | 3.39372978 |
51 | somatic hypermutation of immunoglobulin genes (GO:0016446) | 3.39372978 |
52 | negative regulation of histone modification (GO:0031057) | 3.38512885 |
53 | regulation of centrosome cycle (GO:0046605) | 3.38024213 |
54 | gene silencing by RNA (GO:0031047) | 3.36102037 |
55 | histone H2B ubiquitination (GO:0033523) | 3.35281934 |
56 | nuclear envelope organization (GO:0006998) | 3.33730858 |
57 | NLS-bearing protein import into nucleus (GO:0006607) | 3.30629338 |
58 | negative regulation of chromatin modification (GO:1903309) | 3.30088542 |
59 | regulation of chromosome segregation (GO:0051983) | 3.28723129 |
60 | DNA replication initiation (GO:0006270) | 3.27921503 |
61 | RNA stabilization (GO:0043489) | 3.27842513 |
62 | mRNA stabilization (GO:0048255) | 3.27842513 |
63 | regulation of histone methylation (GO:0031060) | 3.27426669 |
64 | protein localization to chromosome (GO:0034502) | 3.25857845 |
65 | peptidyl-lysine dimethylation (GO:0018027) | 3.24482593 |
66 | chromatin assembly or disassembly (GO:0006333) | 3.24302894 |
67 | histone demethylation (GO:0016577) | 3.23844322 |
68 | sister chromatid cohesion (GO:0007062) | 3.23839741 |
69 | chromosome condensation (GO:0030261) | 3.23515126 |
70 | negative regulation of DNA repair (GO:0045738) | 3.23182614 |
71 | DNA conformation change (GO:0071103) | 3.22743462 |
72 | regulation of translational fidelity (GO:0006450) | 3.19926270 |
73 | protein K6-linked ubiquitination (GO:0085020) | 3.19674122 |
74 | IMP biosynthetic process (GO:0006188) | 3.16707099 |
75 | spindle assembly involved in mitosis (GO:0090307) | 3.16641446 |
76 | negative regulation of retinoic acid receptor signaling pathway (GO:0048387) | 3.16519556 |
77 | negative regulation of mRNA metabolic process (GO:1903312) | 3.15426700 |
78 | regulation of NFAT protein import into nucleus (GO:0051532) | 3.14683948 |
79 | establishment of chromosome localization (GO:0051303) | 3.14280307 |
80 | negative regulation of mRNA processing (GO:0050686) | 3.13935052 |
81 | regulation of DNA endoreduplication (GO:0032875) | 3.13335504 |
82 | determination of adult lifespan (GO:0008340) | 3.11334191 |
83 | gene silencing (GO:0016458) | 3.11267031 |
84 | meiotic chromosome segregation (GO:0045132) | 3.08947232 |
85 | histone H3-K9 methylation (GO:0051567) | 3.04723651 |
86 | kinetochore organization (GO:0051383) | 3.03565103 |
87 | attachment of spindle microtubules to kinetochore (GO:0008608) | 3.03276835 |
88 | mRNA transport (GO:0051028) | 3.02870301 |
89 | microtubule cytoskeleton organization involved in mitosis (GO:1902850) | 3.02596468 |
90 | protein export from nucleus (GO:0006611) | 3.02256660 |
91 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 3.01111121 |
92 | regulation of gene silencing (GO:0060968) | 3.00549958 |
93 | regulation of centrosome duplication (GO:0010824) | 2.98372561 |
94 | regulation of mitotic metaphase/anaphase transition (GO:0030071) | 2.97217304 |
95 | regulation of telomere maintenance via telomerase (GO:0032210) | 2.96302129 |
96 | spliceosomal tri-snRNP complex assembly (GO:0000244) | 2.95800035 |
97 | DNA replication checkpoint (GO:0000076) | 2.95698169 |
98 | chromatin silencing (GO:0006342) | 2.95441890 |
99 | DNA packaging (GO:0006323) | 2.95382514 |
100 | histone H3-K9 demethylation (GO:0033169) | 2.93303279 |
101 | histone H3-K4 methylation (GO:0051568) | 2.92177424 |
102 | regulation of metaphase/anaphase transition of cell cycle (GO:1902099) | 2.92073237 |
103 | chromosome segregation (GO:0007059) | 2.92003196 |
104 | cellular protein complex localization (GO:0034629) | 2.91558652 |
105 | nucleobase biosynthetic process (GO:0046112) | 2.90338026 |
106 | protein complex localization (GO:0031503) | 2.89637329 |
107 | synaptonemal complex assembly (GO:0007130) | 2.89614270 |
108 | stress granule assembly (GO:0034063) | 2.89221438 |
109 | spindle checkpoint (GO:0031577) | 2.88602561 |
110 | N-terminal protein amino acid acetylation (GO:0006474) | 2.88452711 |
111 | histone H4-K12 acetylation (GO:0043983) | 2.88151776 |
112 | cytoplasmic mRNA processing body assembly (GO:0033962) | 2.87529468 |
113 | regulation of mRNA stability (GO:0043488) | 2.87332683 |
114 | glucocorticoid receptor signaling pathway (GO:0042921) | 2.86430802 |
115 | regulation of mitotic sister chromatid separation (GO:0010965) | 2.85921187 |
116 | regulation of mitotic sister chromatid segregation (GO:0033047) | 2.85921187 |
117 | regulation of sister chromatid segregation (GO:0033045) | 2.85921187 |
118 | nuclear-transcribed mRNA poly(A) tail shortening (GO:0000289) | 2.85175621 |
119 | regulation of DNA damage checkpoint (GO:2000001) | 2.83688837 |
120 | DNA replication-independent nucleosome assembly (GO:0006336) | 2.83244576 |
121 | DNA replication-independent nucleosome organization (GO:0034724) | 2.83244576 |
122 | 3-UTR-mediated mRNA stabilization (GO:0070935) | 2.80451852 |
123 | cellular response to epidermal growth factor stimulus (GO:0071364) | 2.78302844 |
124 | protein demethylation (GO:0006482) | 2.77127011 |
125 | protein dealkylation (GO:0008214) | 2.77127011 |
126 | nucleosome disassembly (GO:0006337) | 2.76017929 |
127 | protein-DNA complex disassembly (GO:0032986) | 2.76017929 |
128 | response to epidermal growth factor (GO:0070849) | 2.75196571 |
129 | regulation of histone H3-K4 methylation (GO:0051569) | 2.74022283 |
130 | embryonic process involved in female pregnancy (GO:0060136) | 2.72237114 |
131 | corticosteroid receptor signaling pathway (GO:0031958) | 2.69836211 |
132 | regulation of RNA stability (GO:0043487) | 2.69298887 |
133 | histone H3-K4 trimethylation (GO:0080182) | 2.67746506 |
134 | negative regulation of RNA splicing (GO:0033119) | 2.66304197 |
135 | V(D)J recombination (GO:0033151) | 2.61284872 |
136 | negative regulation of fibroblast apoptotic process (GO:2000270) | 2.60249002 |
137 | regulation of retinoic acid receptor signaling pathway (GO:0048385) | 2.59249881 |
138 | peptidyl-threonine phosphorylation (GO:0018107) | 2.59074324 |
139 | regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083) | 2.58305471 |
140 | nucleus organization (GO:0006997) | 2.56061711 |
141 | DNA synthesis involved in DNA repair (GO:0000731) | 2.55782240 |
142 | positive regulation of cell cycle checkpoint (GO:1901978) | 2.55760369 |
143 | positive regulation of transcription from RNA polymerase III promoter (GO:0045945) | 2.54812329 |
144 | trophectodermal cell differentiation (GO:0001829) | 2.53414900 |
145 | alternative mRNA splicing, via spliceosome (GO:0000380) | 2.51955866 |
146 | DNA strand elongation involved in DNA replication (GO:0006271) | 2.49644433 |
147 | peptidyl-threonine modification (GO:0018210) | 2.49008408 |
Rank | Gene Set | Z-score |
---|---|---|
1 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 6.13243866 |
2 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 4.02968951 |
3 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 3.59808281 |
4 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 3.24203407 |
5 | * KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 3.16340477 |
6 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 3.10660166 |
7 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.85415608 |
8 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 2.67634917 |
9 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 2.58398686 |
10 | SMAD1_18555785_ChIP-Seq_MESCs_Mouse | 2.47132817 |
11 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 2.46933333 |
12 | MYC_22102868_ChIP-Seq_BL_Human | 2.46668682 |
13 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 2.30997504 |
14 | AR_21909140_ChIP-Seq_LNCAP_Human | 2.30090592 |
15 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 2.23609443 |
16 | E2F7_22180533_ChIP-Seq_HELA_Human | 10.9163758 |
17 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.96524602 |
18 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.92018938 |
19 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 1.90645938 |
20 | CLOCK_20551151_ChIP-Seq_293T_Human | 1.89602553 |
21 | KLF5_18264089_ChIP-ChIP_MESCs_Mouse | 1.86447927 |
22 | KLF4_18264089_ChIP-ChIP_MESCs_Mouse | 1.86447927 |
23 | KLF2_18264089_ChIP-ChIP_MESCs_Mouse | 1.86447927 |
24 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.82304563 |
25 | SALL4_18804426_ChIP-ChIP_MESCs_Mouse | 1.80526922 |
26 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 1.78818961 |
27 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.75399597 |
28 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.69879631 |
29 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.66671850 |
30 | ZIC3_20872845_ChIP-ChIP_MESCs_Mouse | 1.63216605 |
31 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.62209880 |
32 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 1.61623407 |
33 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 1.56009642 |
34 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 1.52639664 |
35 | CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat | 1.48902817 |
36 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 1.48350378 |
37 | NANOG_18700969_ChIP-ChIP_MESCs_Mouse | 1.47771795 |
38 | * CREM_20920259_ChIP-Seq_GC1-SPG_Mouse | 1.47512143 |
39 | NACC1_18358816_ChIP-ChIP_MESCs_Mouse | 1.47244511 |
40 | KDM5A_27292631_Chip-Seq_BREAST_Human | 1.46796866 |
41 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 1.44441737 |
42 | ZNF263_19887448_ChIP-Seq_K562_Human | 1.44015724 |
43 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.43740704 |
44 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.43393383 |
45 | SMAD3_22036565_ChIP-Seq_ESCs_Mouse | 1.42472196 |
46 | ZFP281_18358816_ChIP-ChIP_MESCs_Mouse | 1.41393047 |
47 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.40819496 |
48 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.38509783 |
49 | KLF4_18555785_ChIP-Seq_MESCs_Mouse | 1.36270506 |
50 | NANOG_21062744_ChIP-ChIP_HESCs_Human | 1.36207455 |
51 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 1.35492382 |
52 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 1.34592033 |
53 | TCF3_18692474_ChIP-Seq_MESCs_Mouse | 1.33890933 |
54 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.33838288 |
55 | HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse | 1.33303161 |
56 | TCF3_18692474_ChIP-Seq_MEFs_Mouse | 1.30276262 |
57 | GATA1_22025678_ChIP-Seq_K562_Human | 1.29936010 |
58 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.26322034 |
59 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.25777347 |
60 | KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.24811533 |
61 | * TCF7_22412390_ChIP-Seq_EML_Mouse | 1.24027263 |
62 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.23742849 |
63 | NANOG_18347094_ChIP-ChIP_MESCs_Mouse | 1.22544825 |
64 | * MYB_26560356_Chip-Seq_TH1_Human | 1.21573754 |
65 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.20829519 |
66 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.20356345 |
67 | SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse | 1.20154715 |
68 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.19791442 |
69 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 1.19502727 |
70 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.18785826 |
71 | SOX2_27498859_Chip-Seq_STOMACH_Mouse | 1.16145196 |
72 | MAF_26560356_Chip-Seq_TH1_Human | 1.14922233 |
73 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.14696088 |
74 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 1.14046782 |
75 | SOX2_19030024_ChIP-ChIP_MESCs_Mouse | 1.13489936 |
76 | WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse | 1.13208604 |
77 | TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 1.11870944 |
78 | * ZFX_18555785_ChIP-Seq_MESCs_Mouse | 1.11262086 |
79 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 1.09982320 |
80 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.09895339 |
81 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 1.09826017 |
82 | PKCTHETA_26484144_Chip-Seq_BREAST_Human | 1.09668074 |
83 | TCF3_18467660_ChIP-ChIP_MESCs_Mouse | 1.09041712 |
84 | ZFP281_27345836_Chip-Seq_ESCs_Mouse | 1.06898157 |
85 | SOX2_18358816_ChIP-ChIP_MESCs_Mouse | 1.06247250 |
86 | * FOXA2_19822575_ChIP-Seq_HepG2_Human | 1.05986001 |
87 | * KDM2B_26808549_Chip-Seq_SUP-B15_Human | 1.04937896 |
88 | FOXO3_23340844_ChIP-Seq_DLD1_Human | 1.04560927 |
89 | DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 1.03355456 |
90 | P300_27058665_Chip-Seq_ZR-75-30cells_Human | 1.02802111 |
91 | KDM2B_26808549_Chip-Seq_DND41_Human | 1.02742653 |
92 | SMAD4_19686287_ChIP-ChIP_HaCaT_Human | 1.02258129 |
93 | CHD1_26751641_Chip-Seq_LNCaP_Human | 1.01830923 |
94 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.01279752 |
95 | * MYB_26560356_Chip-Seq_TH2_Human | 1.00551585 |
96 | GATA6_25053715_ChIP-Seq_YYC3_Human | 1.00096702 |
97 | CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse | 0.98659951 |
98 | ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human | 0.98563015 |
99 | FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human | 0.98424743 |
100 | VDR_23849224_ChIP-Seq_CD4+_Human | 0.98293193 |
101 | * KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 0.97834602 |
102 | KLF4_18358816_ChIP-ChIP_MESCs_Mouse | 0.97798729 |
103 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 0.97663729 |
104 | KDM2B_26808549_Chip-Seq_JURKAT_Human | 0.97063185 |
105 | * POU5F1_16518401_ChIP-PET_MESCs_Mouse | 0.95406181 |
106 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 0.95368232 |
107 | TTF2_22483619_ChIP-Seq_HELA_Human | 0.95095106 |
108 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 0.94823619 |
109 | SOX2_18692474_ChIP-Seq_MESCs_Mouse | 0.93169092 |
110 | SALL4_18804426_ChIP-ChIP_XEN_Mouse | 0.92556415 |
111 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 0.92405099 |
112 | TFEB_21752829_ChIP-Seq_HELA_Human | 0.91431830 |
113 | FOXP3_21729870_ChIP-Seq_TREG_Human | 0.90018317 |
114 | FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human | 0.88744927 |
115 | POU5F1_18347094_ChIP-ChIP_MESCs_Mouse | 0.88693041 |
116 | E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 0.88563339 |
117 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 0.88197042 |
118 | TCF3_18347094_ChIP-ChIP_MESCs_Mouse | 0.87876154 |
119 | CTNNB1_20460455_ChIP-Seq_HCT116_Human | 0.87860831 |
120 | NANOG_18692474_ChIP-Seq_MESCs_Mouse | 0.87581972 |
121 | NKX2-5_21415370_ChIP-Seq_HL-1_Mouse | 0.86315402 |
122 | NCOR1_26117541_ChIP-Seq_K562_Human | 0.86293306 |
123 | KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human | 0.86241433 |
124 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 0.86238212 |
125 | VDR_21846776_ChIP-Seq_THP-1_Human | 0.85456948 |
126 | UTX_26944678_Chip-Seq_JUKART_Human | 0.83460721 |
127 | PU_27001747_Chip-Seq_BMDM_Mouse | 0.83207827 |
128 | EOMES_20176728_ChIP-ChIP_TSCs_Mouse | 0.81644414 |
129 | DMRT1_23473982_ChIP-Seq_TESTES_Mouse | 0.81212114 |
130 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 0.80345512 |
131 | NANOG_18358816_ChIP-ChIP_MESCs_Mouse | 0.79761126 |
132 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 0.78696127 |
133 | ELK1_19687146_ChIP-ChIP_HELA_Human | 0.78695323 |
134 | PRDM5_23873026_ChIP-Seq_MEFs_Mouse | 0.78038048 |
135 | ZFP281_18757296_ChIP-ChIP_E14_Mouse | 0.77977483 |
136 | ATF3_27146783_Chip-Seq_COLON_Human | 0.76887779 |
137 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 0.76821486 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0010094_abnormal_chromosome_stability | 4.14379107 |
2 | MP0003111_abnormal_nucleus_morphology | 4.06869524 |
3 | MP0003693_abnormal_embryo_hatching | 3.88572631 |
4 | MP0008057_abnormal_DNA_replication | 3.88542184 |
5 | MP0004957_abnormal_blastocyst_morpholog | 3.47466992 |
6 | MP0003077_abnormal_cell_cycle | 3.40530504 |
7 | MP0010352_gastrointestinal_tract_polyps | 3.35006109 |
8 | MP0008877_abnormal_DNA_methylation | 3.10431499 |
9 | MP0005076_abnormal_cell_differentiation | 2.97036007 |
10 | MP0010307_abnormal_tumor_latency | 2.93471832 |
11 | MP0003705_abnormal_hypodermis_morpholog | 2.69910299 |
12 | MP0001730_embryonic_growth_arrest | 2.64477653 |
13 | MP0003123_paternal_imprinting | 2.63434191 |
14 | MP0010234_abnormal_vibrissa_follicle | 2.56823786 |
15 | MP0000350_abnormal_cell_proliferation | 2.40714234 |
16 | MP0008058_abnormal_DNA_repair | 2.33586358 |
17 | MP0008007_abnormal_cellular_replicative | 2.15089930 |
18 | MP0001672_abnormal_embryogenesis/_devel | 2.14396942 |
19 | MP0005380_embryogenesis_phenotype | 2.14396942 |
20 | MP0002084_abnormal_developmental_patter | 2.13762826 |
21 | MP0004197_abnormal_fetal_growth/weight/ | 2.02583251 |
22 | MP0002086_abnormal_extraembryonic_tissu | 1.97968897 |
23 | MP0003121_genomic_imprinting | 1.95690193 |
24 | MP0003984_embryonic_growth_retardation | 1.95073196 |
25 | MP0001697_abnormal_embryo_size | 1.94741048 |
26 | MP0002088_abnormal_embryonic_growth/wei | 1.93165534 |
27 | MP0003787_abnormal_imprinting | 1.90925058 |
28 | MP0002085_abnormal_embryonic_tissue | 1.87141283 |
29 | MP0005451_abnormal_body_composition | 1.85927193 |
30 | MP0005409_darkened_coat_color | 1.83718332 |
31 | MP0003890_abnormal_embryonic-extraembry | 1.82146298 |
32 | MP0002080_prenatal_lethality | 1.67561774 |
33 | MP0003656_abnormal_erythrocyte_physiolo | 1.62081328 |
34 | MP0008932_abnormal_embryonic_tissue | 1.52012484 |
35 | MP0004808_abnormal_hematopoietic_stem | 1.51293152 |
36 | MP0004264_abnormal_extraembryonic_tissu | 1.50678536 |
37 | MP0002877_abnormal_melanocyte_morpholog | 1.50428536 |
38 | MP0003786_premature_aging | 1.48383588 |
39 | MP0002396_abnormal_hematopoietic_system | 1.46462368 |
40 | MP0001929_abnormal_gametogenesis | 1.44939293 |
41 | MP0000569_abnormal_digit_pigmentation | 1.44761034 |
42 | MP0003453_abnormal_keratinocyte_physiol | 1.44142172 |
43 | MP0002210_abnormal_sex_determination | 1.40944381 |
44 | MP0001849_ear_inflammation | 1.37724456 |
45 | MP0003567_abnormal_fetal_cardiomyocyte | 1.36745001 |
46 | MP0003566_abnormal_cell_adhesion | 1.35145594 |
47 | MP0003119_abnormal_digestive_system | 1.33892930 |
48 | MP0008260_abnormal_autophagy | 1.32435663 |
49 | MP0002653_abnormal_ependyma_morphology | 1.31631524 |
50 | MP0009703_decreased_birth_body | 1.30240742 |
51 | MP0009278_abnormal_bone_marrow | 1.28034806 |
52 | MP0001145_abnormal_male_reproductive | 1.26507963 |
53 | MP0004185_abnormal_adipocyte_glucose | 1.25424547 |
54 | MP0009672_abnormal_birth_weight | 1.23040785 |
55 | MP0001293_anophthalmia | 1.22733717 |
56 | MP0000313_abnormal_cell_death | 1.18645011 |
57 | MP0000537_abnormal_urethra_morphology | 1.17736615 |
58 | MP0009053_abnormal_anal_canal | 1.17700224 |
59 | MP0002019_abnormal_tumor_incidence | 1.16273390 |
60 | MP0000653_abnormal_sex_gland | 1.11610552 |
61 | MP0003943_abnormal_hepatobiliary_system | 1.11267155 |
62 | MP0005666_abnormal_adipose_tissue | 1.08703229 |
63 | MP0001545_abnormal_hematopoietic_system | 1.08284600 |
64 | MP0005397_hematopoietic_system_phenotyp | 1.08284600 |
65 | MP0003303_peritoneal_inflammation | 1.07707809 |
66 | MP0004381_abnormal_hair_follicle | 1.06041317 |
67 | MP0005187_abnormal_penis_morphology | 1.05239326 |
68 | MP0010630_abnormal_cardiac_muscle | 1.02661396 |
69 | MP0003221_abnormal_cardiomyocyte_apopto | 1.01882438 |
70 | MP0003698_abnormal_male_reproductive | 1.00361053 |
71 | MP0002089_abnormal_postnatal_growth/wei | 1.00206853 |
72 | MP0000703_abnormal_thymus_morphology | 0.99780499 |
73 | MP0000490_abnormal_crypts_of | 0.98916103 |
74 | MP0005623_abnormal_meninges_morphology | 0.98256590 |
75 | MP0002092_abnormal_eye_morphology | 0.96994988 |
76 | MP0001915_intracranial_hemorrhage | 0.96021899 |
77 | MP0002925_abnormal_cardiovascular_devel | 0.93508985 |
78 | MP0001216_abnormal_epidermal_layer | 0.92437071 |
79 | MP0000733_abnormal_muscle_development | 0.92258481 |
80 | MP0005621_abnormal_cell_physiology | 0.91404521 |
81 | MP0010678_abnormal_skin_adnexa | 0.89749631 |
82 | MP0008770_decreased_survivor_rate | 0.89653705 |
83 | MP0000428_abnormal_craniofacial_morphol | 0.89321608 |
84 | MP0003937_abnormal_limbs/digits/tail_de | 0.88936258 |
85 | MP0000627_abnormal_mammary_gland | 0.88589065 |
86 | MP0009697_abnormal_copulation | 0.88535327 |
87 | MP0004947_skin_inflammation | 0.87500403 |
88 | MP0000377_abnormal_hair_follicle | 0.86722990 |
89 | MP0004233_abnormal_muscle_weight | 0.86144858 |
90 | MP0003861_abnormal_nervous_system | 0.85984836 |
91 | MP0005023_abnormal_wound_healing | 0.85818962 |
92 | MP0003868_abnormal_feces_composition | 0.84852452 |
93 | MP0003300_gastrointestinal_ulcer | 0.83410242 |
94 | MP0005384_cellular_phenotype | 0.83051358 |
95 | MP0001666_abnormal_nutrient_absorption | 0.82964805 |
96 | MP0002098_abnormal_vibrissa_morphology | 0.82719926 |
97 | MP0002722_abnormal_immune_system | 0.81816191 |
98 | MP0005410_abnormal_fertilization | 0.79887162 |
99 | MP0000432_abnormal_head_morphology | 0.79816854 |
100 | MP0002161_abnormal_fertility/fecundity | 0.79739616 |
101 | MP0003935_abnormal_craniofacial_develop | 0.79430408 |
102 | MP0009333_abnormal_splenocyte_physiolog | 0.78884477 |
103 | MP0002009_preneoplasia | 0.78161758 |
104 | MP0003115_abnormal_respiratory_system | 0.75918244 |
105 | MP0002697_abnormal_eye_size | 0.75592370 |
106 | MP0000566_synostosis | 0.73598726 |
107 | MP0005310_abnormal_salivary_gland | 0.71784470 |
108 | MP0000685_abnormal_immune_system | 0.71431984 |
109 | MP0009931_abnormal_skin_appearance | 0.70581803 |
110 | MP0001853_heart_inflammation | 0.70489163 |
111 | MP0003941_abnormal_skin_development | 0.69885494 |
112 | MP0000689_abnormal_spleen_morphology | 0.69294001 |
113 | MP0001784_abnormal_fluid_regulation | 0.68663195 |
114 | MP0003315_abnormal_perineum_morphology | 0.68189622 |
115 | MP0002796_impaired_skin_barrier | 0.67547932 |
116 | MP0002398_abnormal_bone_marrow | 0.67460903 |
117 | MP0005501_abnormal_skin_physiology | 0.67219603 |
118 | MP0003763_abnormal_thymus_physiology | 0.67063646 |
119 | MP0001286_abnormal_eye_development | 0.67027710 |
120 | MP0003718_maternal_effect | 0.66976049 |
121 | MP0002006_tumorigenesis | 0.65331639 |
122 | MP0008961_abnormal_basal_metabolism | 0.65205837 |
123 | MP0002060_abnormal_skin_morphology | 0.64816708 |
124 | MP0002166_altered_tumor_susceptibility | 0.64531225 |
125 | MP0001119_abnormal_female_reproductive | 0.64074930 |
126 | MP0000266_abnormal_heart_morphology | 0.63920023 |
127 | MP0002111_abnormal_tail_morphology | 0.63639646 |
128 | MP0003699_abnormal_female_reproductive | 0.63536997 |
129 | MP0002429_abnormal_blood_cell | 0.62736149 |
130 | MP0003091_abnormal_cell_migration | 0.62700041 |
131 | MP0003283_abnormal_digestive_organ | 0.62308151 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Ependymoma (HP:0002888) | 4.70589047 |
2 | Abnormality of the astrocytes (HP:0100707) | 3.74323382 |
3 | Astrocytoma (HP:0009592) | 3.74323382 |
4 | Volvulus (HP:0002580) | 3.63794243 |
5 | Medulloblastoma (HP:0002885) | 3.44651957 |
6 | Nephroblastoma (Wilms tumor) (HP:0002667) | 3.35287446 |
7 | Abnormality of the labia minora (HP:0012880) | 3.31539409 |
8 | Neoplasm of the oral cavity (HP:0100649) | 3.30129738 |
9 | Asymmetry of the thorax (HP:0001555) | 3.08265085 |
10 | Embryonal renal neoplasm (HP:0011794) | 3.07043377 |
11 | Colon cancer (HP:0003003) | 3.06923366 |
12 | Rhabdomyosarcoma (HP:0002859) | 3.06393033 |
13 | Glioma (HP:0009733) | 3.06185001 |
14 | Biliary tract neoplasm (HP:0100574) | 3.03629694 |
15 | Agnosia (HP:0010524) | 2.84940123 |
16 | Abnormality of the lower motor neuron (HP:0002366) | 2.75741746 |
17 | Impulsivity (HP:0100710) | 2.71685475 |
18 | Heterotopia (HP:0002282) | 2.71050590 |
19 | Chromsome breakage (HP:0040012) | 2.70421013 |
20 | Basal cell carcinoma (HP:0002671) | 2.68893516 |
21 | Increased nuchal translucency (HP:0010880) | 2.65042182 |
22 | Neoplasm of striated muscle (HP:0009728) | 2.64750509 |
23 | Overlapping toe (HP:0001845) | 2.61916756 |
24 | Selective tooth agenesis (HP:0001592) | 2.59105497 |
25 | Ankyloglossia (HP:0010296) | 2.57274077 |
26 | Birth length less than 3rd percentile (HP:0003561) | 2.56993985 |
27 | Abnormality of the fingertips (HP:0001211) | 2.55057680 |
28 | Progressive external ophthalmoplegia (HP:0000590) | 2.54896844 |
29 | Flat acetabular roof (HP:0003180) | 2.53123211 |
30 | Gastrointestinal carcinoma (HP:0002672) | 2.52591129 |
31 | Malignant gastrointestinal tract tumors (HP:0006749) | 2.52591129 |
32 | Sandal gap (HP:0001852) | 2.52527210 |
33 | Leiomyosarcoma (HP:0100243) | 2.52221359 |
34 | Uterine leiomyosarcoma (HP:0002891) | 2.52221359 |
35 | Prominent nose (HP:0000448) | 2.46656693 |
36 | Deep venous thrombosis (HP:0002625) | 2.45442474 |
37 | Dysmetric saccades (HP:0000641) | 2.42930967 |
38 | Abnormality of chromosome stability (HP:0003220) | 2.39263813 |
39 | Deviation of the thumb (HP:0009603) | 2.39009248 |
40 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 2.38000012 |
41 | Sparse lateral eyebrow (HP:0005338) | 2.37288731 |
42 | Proximal placement of thumb (HP:0009623) | 2.36416937 |
43 | Missing ribs (HP:0000921) | 2.34664143 |
44 | Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042) | 2.31627157 |
45 | Short 4th metacarpal (HP:0010044) | 2.31627157 |
46 | Diastasis recti (HP:0001540) | 2.30868922 |
47 | Facial hemangioma (HP:0000329) | 2.30097996 |
48 | Cafe-au-lait spot (HP:0000957) | 2.24884225 |
49 | Bladder carcinoma (HP:0002862) | 2.22503822 |
50 | Bladder neoplasm (HP:0009725) | 2.22503822 |
51 | Ectopic kidney (HP:0000086) | 2.15756560 |
52 | Deep palmar crease (HP:0006191) | 2.14194140 |
53 | Long eyelashes (HP:0000527) | 2.12991309 |
54 | Truncal obesity (HP:0001956) | 2.12776894 |
55 | Embryonal neoplasm (HP:0002898) | 2.12691392 |
56 | Urethral obstruction (HP:0000796) | 2.09509931 |
57 | Neonatal hypoglycemia (HP:0001998) | 2.09320975 |
58 | Parkinsonism with favorable response to dopaminergic medication (HP:0002548) | 2.09016306 |
59 | Hereditary nonpolyposis colorectal carcinoma (HP:0006716) | 2.09012624 |
60 | High pitched voice (HP:0001620) | 2.08748911 |
61 | Insidious onset (HP:0003587) | 2.08099161 |
62 | Termporal pattern (HP:0011008) | 2.08099161 |
63 | Vertebral arch anomaly (HP:0008438) | 2.06525516 |
64 | Papillary thyroid carcinoma (HP:0002895) | 2.06227370 |
65 | Hepatoblastoma (HP:0002884) | 2.03968000 |
66 | Hyperacusis (HP:0010780) | 2.02911594 |
67 | Amaurosis fugax (HP:0100576) | 2.02711973 |
68 | Aplasia/Hypoplasia of the sternum (HP:0006714) | 2.01747314 |
69 | Patellar aplasia (HP:0006443) | 2.01659793 |
70 | Shawl scrotum (HP:0000049) | 2.01036139 |
71 | Abnormal foot bone ossification (HP:0010675) | 1.99790093 |
72 | Renal cell carcinoma (HP:0005584) | 1.98486628 |
73 | Abnormality of oral frenula (HP:0000190) | 1.96428386 |
74 | Aplasia/Hypoplasia of the 1st metacarpal (HP:0010026) | 1.93339826 |
75 | Short 1st metacarpal (HP:0010034) | 1.93339826 |
76 | Hypopigmentation of the fundus (HP:0007894) | 1.92694255 |
77 | Myelodysplasia (HP:0002863) | 1.92281460 |
78 | Pelvic girdle muscle weakness (HP:0003749) | 1.92267038 |
79 | Short humerus (HP:0005792) | 1.90907633 |
80 | Acanthocytosis (HP:0001927) | 1.88781820 |
81 | Viral hepatitis (HP:0006562) | 1.85842244 |
82 | Pseudobulbar signs (HP:0002200) | 1.85451323 |
83 | Broad palm (HP:0001169) | 1.84775940 |
84 | Uterine neoplasm (HP:0010784) | 1.84087415 |
85 | Abnormal biliary tract morphology (HP:0012440) | 1.83877616 |
86 | Absent radius (HP:0003974) | 1.83475792 |
87 | Supernumerary ribs (HP:0005815) | 1.83311865 |
88 | Aplasia/Hypoplasia of the patella (HP:0006498) | 1.82683660 |
89 | Skull defect (HP:0001362) | 1.82584883 |
90 | Abnormality of chromosome segregation (HP:0002916) | 1.82427477 |
91 | Metaphyseal cupping (HP:0003021) | 1.82365027 |
92 | Advanced eruption of teeth (HP:0006288) | 1.81481268 |
93 | Dislocated radial head (HP:0003083) | 1.81268846 |
94 | Limited elbow extension (HP:0001377) | 1.81114820 |
95 | Anal stenosis (HP:0002025) | 1.80880137 |
96 | Aplasia/hypoplasia of the humerus (HP:0006507) | 1.80131940 |
97 | Obsessive-compulsive behavior (HP:0000722) | 1.77599569 |
98 | Macroorchidism (HP:0000053) | 1.77443274 |
99 | Renovascular hypertension (HP:0100817) | 1.77390379 |
100 | Slow saccadic eye movements (HP:0000514) | 1.77005588 |
101 | 11 pairs of ribs (HP:0000878) | 1.75749764 |
102 | Small epiphyses (HP:0010585) | 1.75548750 |
103 | Breast hypoplasia (HP:0003187) | 1.74658861 |
104 | Subaortic stenosis (HP:0001682) | 1.74407371 |
105 | Abnormality of the left ventricular outflow tract (HP:0011103) | 1.74407371 |
106 | Cutis marmorata (HP:0000965) | 1.74286731 |
107 | Neoplasm of the small intestine (HP:0100833) | 1.74114667 |
108 | Abnormality of the distal phalanx of the thumb (HP:0009617) | 1.73954891 |
109 | Adenoma sebaceum (HP:0009720) | 1.73950795 |
110 | Angiofibromas (HP:0010615) | 1.73950795 |
111 | Low anterior hairline (HP:0000294) | 1.73134753 |
112 | Ovarian neoplasm (HP:0100615) | 1.72999355 |
113 | Subacute progressive viral hepatitis (HP:0006572) | 1.71069719 |
114 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 1.70907166 |
115 | Broad thumb (HP:0011304) | 1.70570500 |
116 | Meckel diverticulum (HP:0002245) | 1.70345685 |
117 | Transitional cell carcinoma of the bladder (HP:0006740) | 1.70143930 |
118 | Neoplasm of the pancreas (HP:0002894) | 1.69579540 |
119 | Hypoplastic labia majora (HP:0000059) | 1.69546579 |
120 | Cutaneous melanoma (HP:0012056) | 1.69522212 |
121 | Esophageal atresia (HP:0002032) | 1.69521216 |
122 | Absent forearm bone (HP:0003953) | 1.68777494 |
123 | Aplasia involving forearm bones (HP:0009822) | 1.68777494 |
124 | Germ cell neoplasia (HP:0100728) | 1.68466573 |
125 | Narrow palate (HP:0000189) | 1.68328514 |
126 | Short phalanx of the thumb (HP:0009660) | 1.68035671 |
127 | Intestinal polyp (HP:0005266) | 1.67627778 |
128 | Abnormality of the carotid arteries (HP:0005344) | 1.67078060 |
129 | Wide nose (HP:0000445) | 1.67047011 |
130 | Abnormality of the salivary glands (HP:0010286) | 1.66206133 |
131 | Lip pit (HP:0100267) | 1.65799078 |
132 | Deep philtrum (HP:0002002) | 1.65782467 |
133 | Intestinal polyposis (HP:0200008) | 1.64736698 |
134 | Acute myeloid leukemia (HP:0004808) | 1.64596569 |
135 | Syringomyelia (HP:0003396) | 1.64575967 |
136 | Spinal cord lesions (HP:0100561) | 1.64575967 |
137 | Relative macrocephaly (HP:0004482) | 1.64323995 |
138 | Amyotrophic lateral sclerosis (HP:0007354) | 1.64323994 |
139 | Spinal muscular atrophy (HP:0007269) | 1.63628232 |
140 | Small intestinal stenosis (HP:0012848) | 1.63605460 |
141 | Duodenal stenosis (HP:0100867) | 1.63605460 |
142 | Atresia of the external auditory canal (HP:0000413) | 1.63536288 |
143 | Abnormality of the 4th metacarpal (HP:0010012) | 1.63482004 |
144 | Hyperkalemia (HP:0002153) | 1.62124180 |
145 | Long palpebral fissure (HP:0000637) | 1.59920849 |
146 | Abnormality of the preputium (HP:0100587) | 1.59259683 |
147 | Thyroid carcinoma (HP:0002890) | 1.58915741 |
148 | Abnormality of cochlea (HP:0000375) | 1.57014502 |
149 | Curly hair (HP:0002212) | 1.56666297 |
150 | Abnormality of the radial head (HP:0003995) | 1.55931705 |
151 | Obstructive sleep apnea (HP:0002870) | 1.55728300 |
152 | Somatic mutation (HP:0001428) | 1.54602825 |
153 | Abnormality of the nasal septum (HP:0000419) | 1.54401176 |
154 | Poikilocytosis (HP:0004447) | 1.52869957 |
155 | Cubitus valgus (HP:0002967) | 1.52377929 |
156 | Acute lymphatic leukemia (HP:0006721) | 1.51676222 |
157 | Mask-like facies (HP:0000298) | 1.50310379 |
158 | Recurrent viral infections (HP:0004429) | 1.48930192 |
Rank | Gene Set | Z-score |
---|---|---|
1 | CDK12 | 4.58322519 |
2 | CDC7 | 4.29510655 |
3 | SMG1 | 3.07261955 |
4 | EEF2K | 3.02168967 |
5 | NEK2 | 2.84037890 |
6 | PRPF4B | 2.79688220 |
7 | WEE1 | 2.70609344 |
8 | PKN2 | 2.59328218 |
9 | TTK | 2.51982735 |
10 | LATS1 | 2.49344846 |
11 | FGFR4 | 2.36676036 |
12 | PNCK | 2.24096050 |
13 | NEK1 | 2.16868032 |
14 | RPS6KB2 | 1.95313527 |
15 | BRD4 | 1.88129537 |
16 | TSSK6 | 1.74811318 |
17 | MAP3K10 | 1.72341924 |
18 | ALK | 1.71691481 |
19 | STK3 | 1.64132531 |
20 | CHEK1 | 1.60452821 |
21 | SCYL2 | 1.57419490 |
22 | CDK4 | 1.55900705 |
23 | EPHA2 | 1.51994804 |
24 | ATR | 1.51621858 |
25 | CDK6 | 1.50074069 |
26 | STK10 | 1.49605982 |
27 | SRPK1 | 1.46251590 |
28 | PLK1 | 1.45703118 |
29 | CHEK2 | 1.44329209 |
30 | PASK | 1.40791154 |
31 | PDK4 | 1.38521507 |
32 | PDK3 | 1.38521507 |
33 | TRIB3 | 1.36873032 |
34 | PLK3 | 1.34603434 |
35 | MELK | 1.30546052 |
36 | MAP3K8 | 1.27259155 |
37 | AURKB | 1.27213502 |
38 | ATM | 1.26569404 |
39 | WNK1 | 1.23666153 |
40 | TAF1 | 1.23222893 |
41 | CDK7 | 1.20231615 |
42 | MTOR | 1.17222838 |
43 | MAP3K13 | 1.17009262 |
44 | MAP3K14 | 1.16948438 |
45 | CAMK1D | 1.12326796 |
46 | CDK2 | 1.11838792 |
47 | NLK | 1.11318456 |
48 | ACVR1B | 1.07542151 |
49 | LATS2 | 1.05521137 |
50 | BUB1 | 1.04316260 |
51 | ICK | 0.98037186 |
52 | TYRO3 | 0.97696604 |
53 | STK4 | 0.96314791 |
54 | PLK4 | 0.93828616 |
55 | SGK3 | 0.93221250 |
56 | RIPK1 | 0.92316164 |
57 | CAMK1G | 0.91405979 |
58 | YES1 | 0.89655073 |
59 | CDK9 | 0.89545879 |
60 | CSNK1D | 0.86514558 |
61 | BRSK2 | 0.84886173 |
62 | RIPK4 | 0.84375306 |
63 | MAP3K9 | 0.82939224 |
64 | CDK1 | 0.82400489 |
65 | TGFBR1 | 0.82017046 |
66 | SIK1 | 0.81255205 |
67 | EIF2AK3 | 0.80335347 |
68 | PDGFRA | 0.77934462 |
69 | TNIK | 0.77357025 |
70 | SGK2 | 0.75410448 |
71 | MKNK2 | 0.75213511 |
72 | DMPK | 0.75194345 |
73 | PIM1 | 0.74929844 |
74 | CLK1 | 0.74860617 |
75 | EIF2AK1 | 0.72021116 |
76 | NEK6 | 0.70981892 |
77 | TTN | 0.70376724 |
78 | PTK6 | 0.69759980 |
79 | PRKDC | 0.69711460 |
80 | IRAK2 | 0.69549290 |
81 | KSR2 | 0.68578904 |
82 | LRRK2 | 0.67672225 |
83 | CSNK1E | 0.67610374 |
84 | MKNK1 | 0.67473938 |
85 | PAK4 | 0.66001105 |
86 | STK38L | 0.65946839 |
87 | DYRK3 | 0.62997748 |
88 | FLT3 | 0.62909779 |
89 | PDGFRB | 0.62247631 |
90 | FGR | 0.61981551 |
91 | GRK6 | 0.61218560 |
92 | PDK2 | 0.61066245 |
93 | NEK9 | 0.60170389 |
94 | MAPK11 | 0.58830949 |
95 | KSR1 | 0.57780147 |
96 | BRSK1 | 0.57669726 |
97 | MAPK14 | 0.57449913 |
98 | FGFR1 | 0.57443029 |
99 | ERN1 | 0.57324684 |
100 | STK38 | 0.56936058 |
101 | FGFR2 | 0.56560320 |
102 | RPS6KA4 | 0.56428929 |
103 | MARK3 | 0.54150276 |
104 | PRKD3 | 0.54077108 |
105 | FGFR3 | 0.53790616 |
106 | RET | 0.52274848 |
107 | MAP4K1 | 0.50748693 |
108 | PAK2 | 0.49993519 |
109 | RPS6KB1 | 0.48971740 |
110 | GSK3B | 0.48773972 |
111 | AKT3 | 0.48589542 |
112 | IRAK3 | 0.48451524 |
113 | MAP3K1 | 0.48064498 |
114 | BMX | 0.47467834 |
115 | MAPK10 | 0.47083243 |
116 | FRK | 0.45071012 |
117 | TLK1 | 0.44599379 |
118 | AURKA | 0.43905001 |
119 | IRAK1 | 0.43851027 |
120 | CSNK2A2 | 0.43415935 |
121 | MAP3K2 | 0.42705055 |
122 | BRAF | 0.41662051 |
123 | CDC42BPA | 0.40683015 |
124 | TAOK1 | 0.39826938 |
125 | MAP3K6 | 0.39525694 |
126 | STK24 | 0.38324800 |
127 | PRKCI | 0.37353986 |
128 | EIF2AK2 | 0.37182711 |
129 | SIK2 | 0.37166413 |
130 | MAPK1 | 0.37028969 |
131 | AKT1 | 0.35218656 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 3.17750527 |
2 | Mismatch repair_Homo sapiens_hsa03430 | 3.15252548 |
3 | RNA transport_Homo sapiens_hsa03013 | 3.14286517 |
4 | DNA replication_Homo sapiens_hsa03030 | 3.04076448 |
5 | Cell cycle_Homo sapiens_hsa04110 | 2.82016703 |
6 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 2.55322767 |
7 | Spliceosome_Homo sapiens_hsa03040 | 2.50790981 |
8 | One carbon pool by folate_Homo sapiens_hsa00670 | 2.22887650 |
9 | Non-homologous end-joining_Homo sapiens_hsa03450 | 2.04405153 |
10 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.94324735 |
11 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.91444668 |
12 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.78632870 |
13 | Homologous recombination_Homo sapiens_hsa03440 | 1.74553774 |
14 | Oocyte meiosis_Homo sapiens_hsa04114 | 1.74279341 |
15 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 1.70895407 |
16 | Base excision repair_Homo sapiens_hsa03410 | 1.70408774 |
17 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 1.68447213 |
18 | RNA degradation_Homo sapiens_hsa03018 | 1.62721346 |
19 | mTOR signaling pathway_Homo sapiens_hsa04150 | 1.59578189 |
20 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 1.57996696 |
21 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 1.50080226 |
22 | p53 signaling pathway_Homo sapiens_hsa04115 | 1.48594686 |
23 | * Viral carcinogenesis_Homo sapiens_hsa05203 | 1.36845713 |
24 | Lysine degradation_Homo sapiens_hsa00310 | 1.34069314 |
25 | Basal transcription factors_Homo sapiens_hsa03022 | 1.33109074 |
26 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 1.25907109 |
27 | Adherens junction_Homo sapiens_hsa04520 | 1.24653761 |
28 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.23221276 |
29 | Colorectal cancer_Homo sapiens_hsa05210 | 1.17666181 |
30 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 1.16723166 |
31 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 1.14965518 |
32 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 1.13692394 |
33 | HTLV-I infection_Homo sapiens_hsa05166 | 1.11251680 |
34 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.10829078 |
35 | Small cell lung cancer_Homo sapiens_hsa05222 | 1.10115076 |
36 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 1.07915830 |
37 | Hippo signaling pathway_Homo sapiens_hsa04390 | 1.05253461 |
38 | RNA polymerase_Homo sapiens_hsa03020 | 1.04848563 |
39 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 1.04159701 |
40 | Endometrial cancer_Homo sapiens_hsa05213 | 1.02163129 |
41 | Measles_Homo sapiens_hsa05162 | 1.01480087 |
42 | Thyroid cancer_Homo sapiens_hsa05216 | 0.97421605 |
43 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.97361003 |
44 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.93676202 |
45 | * Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.90189631 |
46 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.89703496 |
47 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.85992176 |
48 | Alcoholism_Homo sapiens_hsa05034 | 0.85921761 |
49 | Prostate cancer_Homo sapiens_hsa05215 | 0.84195678 |
50 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.80795058 |
51 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 0.79579671 |
52 | * Herpes simplex infection_Homo sapiens_hsa05168 | 0.79474651 |
53 | Glioma_Homo sapiens_hsa05214 | 0.79141266 |
54 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.78652613 |
55 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.75986639 |
56 | Hepatitis C_Homo sapiens_hsa05160 | 0.74493524 |
57 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.74469302 |
58 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.73372255 |
59 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.72374050 |
60 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.69155002 |
61 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.69014877 |
62 | Tight junction_Homo sapiens_hsa04530 | 0.67617008 |
63 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.67256772 |
64 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.65408674 |
65 | * FoxO signaling pathway_Homo sapiens_hsa04068 | 0.64914052 |
66 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.64826187 |
67 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.63762064 |
68 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.63051289 |
69 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.61886131 |
70 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 0.61122314 |
71 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.60981622 |
72 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.60818997 |
73 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.60223696 |
74 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.59593036 |
75 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.59540655 |
76 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.58910286 |
77 | Pathways in cancer_Homo sapiens_hsa05200 | 0.58793723 |
78 | Bladder cancer_Homo sapiens_hsa05219 | 0.58417755 |
79 | Hepatitis B_Homo sapiens_hsa05161 | 0.57820498 |
80 | Long-term potentiation_Homo sapiens_hsa04720 | 0.57658355 |
81 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.57616806 |
82 | Prion diseases_Homo sapiens_hsa05020 | 0.57030320 |
83 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.56949224 |
84 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.56561012 |
85 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.56201820 |
86 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.55880059 |
87 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.55249283 |
88 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.54648381 |
89 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.53383533 |
90 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.53367935 |
91 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 0.51016210 |
92 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.50879433 |
93 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.50432461 |
94 | Melanoma_Homo sapiens_hsa05218 | 0.49857625 |
95 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.48575517 |
96 | Focal adhesion_Homo sapiens_hsa04510 | 0.48204340 |
97 | Osteoclast differentiation_Homo sapiens_hsa04380 | 0.47920922 |
98 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.47144282 |
99 | Apoptosis_Homo sapiens_hsa04210 | 0.46056752 |
100 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.46053811 |
101 | Insulin resistance_Homo sapiens_hsa04931 | 0.45793350 |
102 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.45668938 |
103 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.45590031 |
104 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.45336339 |
105 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.45096160 |
106 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.45060343 |
107 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.44440867 |
108 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.44367556 |
109 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.44119828 |
110 | Viral myocarditis_Homo sapiens_hsa05416 | 0.43734156 |
111 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.43682668 |
112 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.42203557 |
113 | Influenza A_Homo sapiens_hsa05164 | 0.41961515 |
114 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 0.41212699 |
115 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.40877506 |
116 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.39866643 |
117 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.39528604 |
118 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.39042260 |