

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | fatty acid elongation (GO:0030497) | 8.66760029 |
| 2 | regulation of memory T cell differentiation (GO:0043380) | 8.18209242 |
| 3 | germinal center formation (GO:0002467) | 7.79600760 |
| 4 | growth hormone receptor signaling pathway (GO:0060396) | 7.31455014 |
| 5 | negative regulation of B cell apoptotic process (GO:0002903) | 6.98825317 |
| 6 | innate immune response in mucosa (GO:0002227) | 6.79659313 |
| 7 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 6.68578717 |
| 8 | cellular response to growth hormone stimulus (GO:0071378) | 6.47429747 |
| 9 | negative regulation of Rho protein signal transduction (GO:0035024) | 6.36840962 |
| 10 | negative regulation of B cell mediated immunity (GO:0002713) | 6.32123764 |
| 11 | negative regulation of immunoglobulin mediated immune response (GO:0002890) | 6.32123764 |
| 12 | positive regulation of hematopoietic progenitor cell differentiation (GO:1901534) | 6.17403943 |
| 13 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 6.11065064 |
| 14 | negative regulation of T-helper cell differentiation (GO:0045623) | 6.06642835 |
| 15 | negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371) | 6.06642835 |
| 16 | negative regulation of viral entry into host cell (GO:0046597) | 5.98294360 |
| 17 | phagocytosis, recognition (GO:0006910) | 5.97293471 |
| 18 | regulation of germinal center formation (GO:0002634) | 5.91907027 |
| 19 | regulation of hypersensitivity (GO:0002883) | 5.82268140 |
| 20 | mucosal immune response (GO:0002385) | 5.66438056 |
| 21 | regulation of antigen processing and presentation of peptide antigen (GO:0002583) | 5.59232429 |
| 22 | regulation of viral entry into host cell (GO:0046596) | 5.39513026 |
| 23 | rRNA transcription (GO:0009303) | 5.37064821 |
| 24 | organ or tissue specific immune response (GO:0002251) | 5.18979981 |
| 25 | antibacterial humoral response (GO:0019731) | 5.18473005 |
| 26 | antigen processing and presentation of endogenous antigen (GO:0019883) | 5.13202647 |
| 27 | negative regulation of type 2 immune response (GO:0002829) | 4.97093516 |
| 28 | regulation of heat generation (GO:0031650) | 4.85825178 |
| 29 | regulation of T-helper 2 cell differentiation (GO:0045628) | 4.81993422 |
| 30 | response to acidic pH (GO:0010447) | 4.78746947 |
| 31 | somite development (GO:0061053) | 4.71503306 |
| 32 | antimicrobial humoral response (GO:0019730) | 4.64983277 |
| 33 | regulation of acute inflammatory response to antigenic stimulus (GO:0002864) | 4.64796572 |
| 34 | negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515) | 4.64023919 |
| 35 | positive regulation of inflammatory response to antigenic stimulus (GO:0002863) | 4.56960382 |
| 36 | negative regulation of JAK-STAT cascade (GO:0046426) | 4.52355411 |
| 37 | regulation of B cell apoptotic process (GO:0002902) | 4.50649954 |
| 38 | negative regulation of alpha-beta T cell differentiation (GO:0046639) | 4.41420832 |
| 39 | cellular response to pH (GO:0071467) | 4.37494334 |
| 40 | negative regulation of defense response to virus (GO:0050687) | 4.25409069 |
| 41 | mRNA cleavage (GO:0006379) | 4.22738791 |
| 42 | cell wall macromolecule catabolic process (GO:0016998) | 4.22738753 |
| 43 | positive regulation of natural killer cell differentiation (GO:0032825) | 4.14073954 |
| 44 | positive regulation of antigen processing and presentation (GO:0002579) | 4.08084791 |
| 45 | negative regulation of DNA recombination (GO:0045910) | 4.04921333 |
| 46 | antigen processing and presentation via MHC class Ib (GO:0002475) | 4.02626706 |
| 47 | regulation of meiosis I (GO:0060631) | 3.98459807 |
| 48 | interleukin-6-mediated signaling pathway (GO:0070102) | 3.94367949 |
| 49 | histone H2A acetylation (GO:0043968) | 3.91172217 |
| 50 | detection of mechanical stimulus involved in sensory perception of sound (GO:0050910) | 3.86823238 |
| 51 | urate metabolic process (GO:0046415) | 3.83873847 |
| 52 | polyamine biosynthetic process (GO:0006596) | 3.78103376 |
| 53 | regulation of hematopoietic progenitor cell differentiation (GO:1901532) | 3.77643159 |
| 54 | DNA damage induced protein phosphorylation (GO:0006975) | 3.77136774 |
| 55 | positive regulation of myeloid leukocyte mediated immunity (GO:0002888) | 3.73878003 |
| 56 | negative regulation of mast cell activation (GO:0033004) | 3.68734279 |
| 57 | signal peptide processing (GO:0006465) | 3.64177320 |
| 58 | cell wall macromolecule metabolic process (GO:0044036) | 3.63861090 |
| 59 | positive regulation of T-helper 1 type immune response (GO:0002827) | 3.63791487 |
| 60 | entrainment of circadian clock by photoperiod (GO:0043153) | 3.60725857 |
| 61 | regulation of viral release from host cell (GO:1902186) | 3.60167747 |
| 62 | response to growth hormone (GO:0060416) | 3.46815018 |
| 63 | positive regulation of protein homodimerization activity (GO:0090073) | 3.42196083 |
| 64 | regulation of antigen processing and presentation (GO:0002577) | 3.41288711 |
| 65 | negative regulation of viral transcription (GO:0032897) | 3.41076660 |
| 66 | erythrocyte development (GO:0048821) | 3.36796930 |
| 67 | regulation of T-helper cell differentiation (GO:0045622) | 3.36766084 |
| 68 | positive regulation of osteoclast differentiation (GO:0045672) | 3.35547019 |
| 69 | peptidyl-histidine modification (GO:0018202) | 3.35418484 |
| 70 | phosphate ion transmembrane transport (GO:0035435) | 3.28917579 |
| 71 | cellular biogenic amine biosynthetic process (GO:0042401) | 3.28037620 |
| 72 | mitochondrial DNA replication (GO:0006264) | 3.26431513 |
| 73 | transcription from RNA polymerase III promoter (GO:0006383) | 3.23586080 |
| 74 | DNA integration (GO:0015074) | 3.21224970 |
| 75 | intraciliary transport (GO:0042073) | 3.12980236 |
| 76 | amine biosynthetic process (GO:0009309) | 3.09207739 |
| 77 | sulfate transport (GO:0008272) | 3.09032252 |
| 78 | entrainment of circadian clock (GO:0009649) | 3.03768774 |
| 79 | phosphate ion transport (GO:0006817) | 3.03460917 |
| 80 | DNA unwinding involved in DNA replication (GO:0006268) | 3.00926895 |
| 81 | protein-chromophore linkage (GO:0018298) | 3.00765695 |
| 82 | positive regulation of T cell mediated immunity (GO:0002711) | 2.99364879 |
| 83 | poly(A)+ mRNA export from nucleus (GO:0016973) | 2.99327335 |
| 84 | sulfate transmembrane transport (GO:1902358) | 2.98895672 |
| 85 | histone H2A ubiquitination (GO:0033522) | 2.98402045 |
| 86 | regulation of natural killer cell differentiation (GO:0032823) | 2.96105350 |
| 87 | purine deoxyribonucleoside triphosphate metabolic process (GO:0009215) | 2.94508939 |
| 88 | long-chain fatty-acyl-CoA biosynthetic process (GO:0035338) | 2.94088223 |
| 89 | positive regulation of T cell mediated cytotoxicity (GO:0001916) | 2.94072911 |
| 90 | histone H2B ubiquitination (GO:0033523) | 2.93993980 |
| 91 | JAK-STAT cascade involved in growth hormone signaling pathway (GO:0060397) | 2.91355231 |
| 92 | positive regulation of granulocyte macrophage colony-stimulating factor production (GO:0032725) | 2.85409189 |
| 93 | myeloid leukocyte mediated immunity (GO:0002444) | 2.84652416 |
| 94 | regulation of megakaryocyte differentiation (GO:0045652) | 2.83873860 |
| 95 | photoperiodism (GO:0009648) | 2.82543324 |
| 96 | negative regulation of circadian rhythm (GO:0042754) | 2.81410859 |
| 97 | sensory perception of taste (GO:0050909) | 2.79048765 |
| 98 | regulation of defense response to virus by host (GO:0050691) | 2.74260368 |
| 99 | nucleosome assembly (GO:0006334) | 2.73398078 |
| 100 | immunoglobulin mediated immune response (GO:0016064) | 2.73276791 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 6.54474747 |
| 2 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 4.57106087 |
| 3 | ZNF274_21170338_ChIP-Seq_K562_Hela | 4.31099013 |
| 4 | CIITA_25753668_ChIP-Seq_RAJI_Human | 3.46252284 |
| 5 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 3.01645438 |
| 6 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 2.99519668 |
| 7 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 2.93943297 |
| 8 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 2.87552380 |
| 9 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 2.86503816 |
| 10 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 2.73758866 |
| 11 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 2.49784345 |
| 12 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 2.44413203 |
| 13 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 2.23182522 |
| 14 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 2.22784124 |
| 15 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 2.12787083 |
| 16 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 2.09118125 |
| 17 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 2.05665810 |
| 18 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.88384292 |
| 19 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.85688668 |
| 20 | STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 1.80047384 |
| 21 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.79833003 |
| 22 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.78829802 |
| 23 | PKCTHETA_26484144_Chip-Seq_BREAST_Human | 1.78593705 |
| 24 | TDRD3_21172665_ChIP-Seq_MCF-7_Human | 1.78229335 |
| 25 | ETS1_22383799_ChIP-Seq_G1ME_Mouse | 1.75830242 |
| 26 | VDR_22108803_ChIP-Seq_LS180_Human | 1.75459465 |
| 27 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.73896308 |
| 28 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 1.73516108 |
| 29 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.69406638 |
| 30 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 1.65282485 |
| 31 | FUS_26573619_Chip-Seq_HEK293_Human | 1.65086639 |
| 32 | KLF1_20508144_ChIP-Seq_FETAL-LIVER-ERYTHROID_Mouse | 1.64580348 |
| 33 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.63473620 |
| 34 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.63461871 |
| 35 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.62576520 |
| 36 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 1.62375620 |
| 37 | LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.56669614 |
| 38 | BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 1.55576166 |
| 39 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.53858170 |
| 40 | RUNX1_17652178_ChIP-ChIP_JURKAT_Human | 1.53415284 |
| 41 | HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse | 1.52919069 |
| 42 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 1.49256019 |
| 43 | EWS_26573619_Chip-Seq_HEK293_Human | 1.46848033 |
| 44 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.46730485 |
| 45 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.42449920 |
| 46 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.41529618 |
| 47 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.40966816 |
| 48 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 1.37441317 |
| 49 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.33501713 |
| 50 | BCL6_25482012_ChIP-Seq_CML-JURL-MK1_Human | 1.33334901 |
| 51 | RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse | 1.32349104 |
| 52 | TP53_16413492_ChIP-PET_HCT116_Human | 1.30474953 |
| 53 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.27914103 |
| 54 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 1.26599034 |
| 55 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.24933876 |
| 56 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.24856418 |
| 57 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 1.23947553 |
| 58 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.23778189 |
| 59 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.22646337 |
| 60 | HIF1A_21447827_ChIP-Seq_MCF-7_Human | 1.22454008 |
| 61 | JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.22027359 |
| 62 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.20938567 |
| 63 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.20938567 |
| 64 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.20836732 |
| 65 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.20836732 |
| 66 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.18579913 |
| 67 | GATA1_19941826_ChIP-Seq_K562_Human | 1.17693221 |
| 68 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.16842789 |
| 69 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.15284121 |
| 70 | SOX9_26525672_Chip-Seq_HEART_Mouse | 1.14181228 |
| 71 | ZNF652_21678463_ChIP-ChIP_ZR75-1_Human | 1.11947339 |
| 72 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.11531605 |
| 73 | E2F1_20622854_ChIP-Seq_HELA_Human | 1.11520747 |
| 74 | SMAD1_18555785_ChIP-Seq_MESCs_Mouse | 1.10097576 |
| 75 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.07380753 |
| 76 | SPI1_23127762_ChIP-Seq_K562_Human | 1.04888901 |
| 77 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.02652405 |
| 78 | TAF2_19829295_ChIP-Seq_ESCs_Human | 0.99488304 |
| 79 | NANOG_18700969_ChIP-ChIP_MESCs_Mouse | 0.98061134 |
| 80 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 0.96734517 |
| 81 | DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 0.96663276 |
| 82 | GATA3_26560356_Chip-Seq_TH2_Human | 0.96660197 |
| 83 | HTT_18923047_ChIP-ChIP_STHdh_Human | 0.95652980 |
| 84 | TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse | 0.94727809 |
| 85 | JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 0.93840342 |
| 86 | ATF3_23680149_ChIP-Seq_GBM1-GSC_Human | 0.93136682 |
| 87 | NCOR_22424771_ChIP-Seq_293T_Human | 0.92709031 |
| 88 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 0.91727578 |
| 89 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 0.91269924 |
| 90 | GATA6_21074721_ChIP-Seq_CACO-2_Human | 0.90967752 |
| 91 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 0.89907923 |
| 92 | TFEB_21752829_ChIP-Seq_HELA_Human | 0.89186486 |
| 93 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.88282433 |
| 94 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 0.86019473 |
| 95 | SALL4_22934838_ChIP-ChIP_CD34+_Human | 0.84120051 |
| 96 | ERA_21632823_ChIP-Seq_H3396_Human | 0.82337353 |
| 97 | RBPJ_21746931_ChIP-Seq_IB4_Human | 0.82085415 |
| 98 | CEBPB_22108803_ChIP-Seq_LS180_Human | 0.80576824 |
| 99 | TCF12/HEB_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.79787092 |
| 100 | GATA6_21074721_ChIP-Seq_CACO-2_Mouse | 0.79678824 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0002138_abnormal_hepatobiliary_system | 9.26616019 |
| 2 | MP0004381_abnormal_hair_follicle | 5.58130571 |
| 3 | MP0008057_abnormal_DNA_replication | 4.80457079 |
| 4 | MP0005075_abnormal_melanosome_morpholog | 4.32384225 |
| 5 | MP0004147_increased_porphyrin_level | 4.25432939 |
| 6 | MP0002638_abnormal_pupillary_reflex | 3.28766256 |
| 7 | MP0001835_abnormal_antigen_presentation | 3.06622174 |
| 8 | MP0005167_abnormal_blood-brain_barrier | 3.06021417 |
| 9 | MP0008875_abnormal_xenobiotic_pharmacok | 2.97636816 |
| 10 | MP0004858_abnormal_nervous_system | 2.96050144 |
| 11 | MP0002166_altered_tumor_susceptibility | 2.92028170 |
| 12 | MP0001853_heart_inflammation | 2.79881571 |
| 13 | MP0002254_reproductive_system_inflammat | 2.78515076 |
| 14 | MP0001542_abnormal_bone_strength | 2.71557624 |
| 15 | MP0005360_urolithiasis | 2.61982974 |
| 16 | MP0002006_tumorigenesis | 2.53215425 |
| 17 | MP0010234_abnormal_vibrissa_follicle | 2.20506044 |
| 18 | MP0000647_abnormal_sebaceous_gland | 2.08390915 |
| 19 | MP0003879_abnormal_hair_cell | 2.03171417 |
| 20 | MP0004043_abnormal_pH_regulation | 1.97487065 |
| 21 | MP0006276_abnormal_autonomic_nervous | 1.75420993 |
| 22 | MP0003195_calcinosis | 1.75173807 |
| 23 | MP0006054_spinal_hemorrhage | 1.74346357 |
| 24 | MP0008995_early_reproductive_senescence | 1.59630374 |
| 25 | MP0003646_muscle_fatigue | 1.58051469 |
| 26 | MP0000685_abnormal_immune_system | 1.52828795 |
| 27 | MP0002277_abnormal_respiratory_mucosa | 1.46415692 |
| 28 | MP0008961_abnormal_basal_metabolism | 1.45427049 |
| 29 | MP0005535_abnormal_body_temperature | 1.44746986 |
| 30 | MP0003172_abnormal_lysosome_physiology | 1.26442864 |
| 31 | MP0001502_abnormal_circadian_rhythm | 1.23980582 |
| 32 | MP0005220_abnormal_exocrine_pancreas | 1.23875454 |
| 33 | MP0001501_abnormal_sleep_pattern | 1.20591569 |
| 34 | MP0003786_premature_aging | 1.19561853 |
| 35 | MP0009785_altered_susceptibility_to | 1.14669394 |
| 36 | MP0002089_abnormal_postnatal_growth/wei | 1.13163432 |
| 37 | MP0002653_abnormal_ependyma_morphology | 1.12440175 |
| 38 | MP0005645_abnormal_hypothalamus_physiol | 1.10654549 |
| 39 | MP0001188_hyperpigmentation | 1.08251683 |
| 40 | MP0002796_impaired_skin_barrier | 1.08245051 |
| 41 | MP0001849_ear_inflammation | 0.93907031 |
| 42 | MP0003787_abnormal_imprinting | 0.92657110 |
| 43 | MP0001727_abnormal_embryo_implantation | 0.91802429 |
| 44 | MP0005310_abnormal_salivary_gland | 0.88919173 |
| 45 | MP0005623_abnormal_meninges_morphology | 0.86511527 |
| 46 | MP0005365_abnormal_bile_salt | 0.85562475 |
| 47 | MP0000427_abnormal_hair_cycle | 0.83212378 |
| 48 | MP0008770_decreased_survivor_rate | 0.80004600 |
| 49 | MP0004947_skin_inflammation | 0.77747853 |
| 50 | MP0000013_abnormal_adipose_tissue | 0.77023336 |
| 51 | MP0003698_abnormal_male_reproductive | 0.76696890 |
| 52 | MP0000613_abnormal_salivary_gland | 0.76563624 |
| 53 | MP0005646_abnormal_pituitary_gland | 0.73900210 |
| 54 | MP0003724_increased_susceptibility_to | 0.73437730 |
| 55 | MP0002295_abnormal_pulmonary_circulatio | 0.73024418 |
| 56 | MP0002405_respiratory_system_inflammati | 0.72327334 |
| 57 | MP0001929_abnormal_gametogenesis | 0.72130824 |
| 58 | MP0005551_abnormal_eye_electrophysiolog | 0.69838351 |
| 59 | MP0000372_irregular_coat_pigmentation | 0.69600557 |
| 60 | MP0004142_abnormal_muscle_tone | 0.69197979 |
| 61 | MP0001873_stomach_inflammation | 0.67433617 |
| 62 | MP0005266_abnormal_metabolism | 0.67419997 |
| 63 | MP0002971_abnormal_brown_adipose | 0.66712450 |
| 64 | MP0009643_abnormal_urine_homeostasis | 0.65846221 |
| 65 | MP0001243_abnormal_dermal_layer | 0.65078177 |
| 66 | MP0006292_abnormal_olfactory_placode | 0.64751448 |
| 67 | MP0008775_abnormal_heart_ventricle | 0.64087227 |
| 68 | MP0002210_abnormal_sex_determination | 0.61573916 |
| 69 | MP0008872_abnormal_physiological_respon | 0.57991322 |
| 70 | MP0004270_analgesia | 0.57580725 |
| 71 | MP0001145_abnormal_male_reproductive | 0.56309742 |
| 72 | MP0002090_abnormal_vision | 0.54709767 |
| 73 | MP0001968_abnormal_touch/_nociception | 0.53486295 |
| 74 | MP0005253_abnormal_eye_physiology | 0.51802089 |
| 75 | MP0009745_abnormal_behavioral_response | 0.50101875 |
| 76 | MP0002229_neurodegeneration | 0.49993950 |
| 77 | MP0004085_abnormal_heartbeat | 0.49186267 |
| 78 | MP0003866_abnormal_defecation | 0.48582431 |
| 79 | MP0005636_abnormal_mineral_homeostasis | 0.47529056 |
| 80 | MP0000653_abnormal_sex_gland | 0.46419926 |
| 81 | MP0004215_abnormal_myocardial_fiber | 0.46392161 |
| 82 | MP0000377_abnormal_hair_follicle | 0.44842678 |
| 83 | MP0001293_anophthalmia | 0.44460054 |
| 84 | MP0001756_abnormal_urination | 0.42707086 |
| 85 | MP0004484_altered_response_of | 0.41519781 |
| 86 | MP0003011_delayed_dark_adaptation | 0.41299862 |
| 87 | MP0005410_abnormal_fertilization | 0.40801663 |
| 88 | MP0005387_immune_system_phenotype | 0.40605312 |
| 89 | MP0001790_abnormal_immune_system | 0.40605312 |
| 90 | MP0003693_abnormal_embryo_hatching | 0.39024742 |
| 91 | MP0008007_abnormal_cellular_replicative | 0.38926501 |
| 92 | MP0005647_abnormal_sex_gland | 0.38018138 |
| 93 | MP0001765_abnormal_ion_homeostasis | 0.36679314 |
| 94 | MP0000609_abnormal_liver_physiology | 0.36408869 |
| 95 | MP0005501_abnormal_skin_physiology | 0.35824195 |
| 96 | MP0002136_abnormal_kidney_physiology | 0.35679059 |
| 97 | MP0002837_dystrophic_cardiac_calcinosis | 0.34670075 |
| 98 | MP0004130_abnormal_muscle_cell | 0.34654310 |
| 99 | MP0004510_myositis | 0.34043104 |
| 100 | MP0006035_abnormal_mitochondrial_morpho | 0.33625367 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Elevated erythrocyte sedimentation rate (HP:0003565) | 9.52390772 |
| 2 | Large eyes (HP:0001090) | 8.98969908 |
| 3 | Abnormality of the fingertips (HP:0001211) | 6.41834595 |
| 4 | Chronic otitis media (HP:0000389) | 6.12639608 |
| 5 | Reduced subcutaneous adipose tissue (HP:0003758) | 5.52695934 |
| 6 | 3-Methylglutaconic aciduria (HP:0003535) | 5.28377604 |
| 7 | Abnormality of alanine metabolism (HP:0010916) | 5.14785600 |
| 8 | Hyperalaninemia (HP:0003348) | 5.14785600 |
| 9 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 5.14785600 |
| 10 | Delayed CNS myelination (HP:0002188) | 4.92110042 |
| 11 | Type II lissencephaly (HP:0007260) | 4.64731753 |
| 12 | Cerebellar dysplasia (HP:0007033) | 4.56077202 |
| 13 | Chronic sinusitis (HP:0011109) | 4.07508076 |
| 14 | Nasal polyposis (HP:0100582) | 3.85984498 |
| 15 | Clubbing of toes (HP:0100760) | 3.82208215 |
| 16 | Basal ganglia calcification (HP:0002135) | 3.65044076 |
| 17 | Macroglossia (HP:0000158) | 3.60056271 |
| 18 | Abnormality of the peritoneum (HP:0002585) | 3.57384950 |
| 19 | Ileus (HP:0002595) | 3.50303749 |
| 20 | Chronic hepatic failure (HP:0100626) | 3.41103686 |
| 21 | Decreased circulating renin level (HP:0003351) | 3.13615789 |
| 22 | Microcytic anemia (HP:0001935) | 3.13612395 |
| 23 | Pancreatic cysts (HP:0001737) | 3.08417556 |
| 24 | Abnormality of the nasal mucosa (HP:0000433) | 3.05423089 |
| 25 | Azoospermia (HP:0000027) | 2.97492991 |
| 26 | Abnormality of the vitamin B12 metabolism (HP:0004341) | 2.94729627 |
| 27 | Mediastinal lymphadenopathy (HP:0100721) | 2.91344068 |
| 28 | Tubulointerstitial nephritis (HP:0001970) | 2.87644948 |
| 29 | Abnormality of vitamin B metabolism (HP:0004340) | 2.79863622 |
| 30 | Atonic seizures (HP:0010819) | 2.79331189 |
| 31 | Prominent nose (HP:0000448) | 2.73180213 |
| 32 | Febrile seizures (HP:0002373) | 2.64055431 |
| 33 | Retinal dysplasia (HP:0007973) | 2.60031122 |
| 34 | Testicular atrophy (HP:0000029) | 2.58870835 |
| 35 | Multiple enchondromatosis (HP:0005701) | 2.58143265 |
| 36 | Hyperkalemia (HP:0002153) | 2.54770114 |
| 37 | Flat occiput (HP:0005469) | 2.50354392 |
| 38 | Arthropathy (HP:0003040) | 2.50169741 |
| 39 | Congenital stationary night blindness (HP:0007642) | 2.49140069 |
| 40 | Cardiomegaly (HP:0001640) | 2.49083141 |
| 41 | Hyperglycinemia (HP:0002154) | 2.48344303 |
| 42 | Pancreatic fibrosis (HP:0100732) | 2.44369531 |
| 43 | Microretrognathia (HP:0000308) | 2.33786683 |
| 44 | Abnormality of the basal ganglia (HP:0002134) | 2.32600040 |
| 45 | Attenuation of retinal blood vessels (HP:0007843) | 2.31492213 |
| 46 | Erythema (HP:0010783) | 2.29812384 |
| 47 | Recurrent bronchitis (HP:0002837) | 2.29506816 |
| 48 | Hypothermia (HP:0002045) | 2.29171252 |
| 49 | True hermaphroditism (HP:0010459) | 2.27633344 |
| 50 | Abnormality of the pleura (HP:0002103) | 2.23649224 |
| 51 | Generalized aminoaciduria (HP:0002909) | 2.15094122 |
| 52 | Methylmalonic acidemia (HP:0002912) | 2.06256822 |
| 53 | Congenital primary aphakia (HP:0007707) | 2.05718314 |
| 54 | Joint contractures involving the joints of the feet (HP:0100492) | 2.02207215 |
| 55 | Flexion contracture of toe (HP:0005830) | 2.02207215 |
| 56 | Gaze-evoked nystagmus (HP:0000640) | 2.00032699 |
| 57 | Gait imbalance (HP:0002141) | 1.99376157 |
| 58 | Calf muscle hypertrophy (HP:0008981) | 1.98007356 |
| 59 | Hypergammaglobulinemia (HP:0010702) | 1.97942260 |
| 60 | Hypoplasia of the pons (HP:0012110) | 1.97133660 |
| 61 | Thyroid carcinoma (HP:0002890) | 1.97079634 |
| 62 | Increased neuronal autofluorescent lipopigment (HP:0002074) | 1.96897201 |
| 63 | Bronchitis (HP:0012387) | 1.95635475 |
| 64 | Medial flaring of the eyebrow (HP:0010747) | 1.94547168 |
| 65 | Hydroxyprolinuria (HP:0003080) | 1.91766954 |
| 66 | Abnormality of proline metabolism (HP:0010907) | 1.91766954 |
| 67 | Abnormal spermatogenesis (HP:0008669) | 1.91634174 |
| 68 | Abnormality of vitamin metabolism (HP:0100508) | 1.89954203 |
| 69 | Abnormality of serum amino acid levels (HP:0003112) | 1.84673597 |
| 70 | Elbow flexion contracture (HP:0002987) | 1.84289935 |
| 71 | Papillary thyroid carcinoma (HP:0002895) | 1.83274540 |
| 72 | Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204) | 1.82452991 |
| 73 | Bronchiectasis (HP:0002110) | 1.81651306 |
| 74 | Nephrogenic diabetes insipidus (HP:0009806) | 1.79755594 |
| 75 | Abnormal drinking behavior (HP:0030082) | 1.76866165 |
| 76 | Polydipsia (HP:0001959) | 1.76866165 |
| 77 | Hypokalemic alkalosis (HP:0001949) | 1.76268574 |
| 78 | Abnormality of the pons (HP:0007361) | 1.75954626 |
| 79 | Muscle hypertrophy of the lower extremities (HP:0008968) | 1.74270215 |
| 80 | Status epilepticus (HP:0002133) | 1.74143793 |
| 81 | Lymphedema (HP:0001004) | 1.73141522 |
| 82 | Absence seizures (HP:0002121) | 1.71676029 |
| 83 | Cone-rod dystrophy (HP:0000548) | 1.71389594 |
| 84 | Abnormality of glycine metabolism (HP:0010895) | 1.70778990 |
| 85 | Abnormality of serine family amino acid metabolism (HP:0010894) | 1.70778990 |
| 86 | Methylmalonic aciduria (HP:0012120) | 1.69778975 |
| 87 | Hypertriglyceridemia (HP:0002155) | 1.68108205 |
| 88 | Acute lymphatic leukemia (HP:0006721) | 1.68098087 |
| 89 | Aplasia/Hypoplasia of the lens (HP:0008063) | 1.67646775 |
| 90 | Clumsiness (HP:0002312) | 1.67276750 |
| 91 | Trismus (HP:0000211) | 1.67170522 |
| 92 | Aplastic anemia (HP:0001915) | 1.65846019 |
| 93 | Abnormality of chloride homeostasis (HP:0011422) | 1.65710982 |
| 94 | Thin upper lip vermilion (HP:0000219) | 1.65685403 |
| 95 | Cystic liver disease (HP:0006706) | 1.65165482 |
| 96 | Hyperaldosteronism (HP:0000859) | 1.63594384 |
| 97 | Lissencephaly (HP:0001339) | 1.63136471 |
| 98 | Abnormality of renin-angiotensin system (HP:0000847) | 1.62049691 |
| 99 | Occipital encephalocele (HP:0002085) | 1.60696032 |
| 100 | Short foot (HP:0001773) | 1.59327407 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | FRK | 5.25564014 |
| 2 | SIK2 | 3.98638975 |
| 3 | ACVR1B | 3.48545181 |
| 4 | CHUK | 2.92354658 |
| 5 | IRAK1 | 2.87470332 |
| 6 | ZAK | 2.87262081 |
| 7 | TLK1 | 2.77780611 |
| 8 | MARK3 | 2.67174985 |
| 9 | WNK4 | 2.55010053 |
| 10 | MST4 | 2.35311586 |
| 11 | FER | 2.33041661 |
| 12 | MAP3K5 | 2.11597090 |
| 13 | KSR1 | 2.07508731 |
| 14 | AKT3 | 1.96605099 |
| 15 | IKBKB | 1.91122768 |
| 16 | EPHA3 | 1.91086182 |
| 17 | SIK3 | 1.82544004 |
| 18 | MAP3K2 | 1.82321499 |
| 19 | MKNK2 | 1.69066462 |
| 20 | CDK12 | 1.67816029 |
| 21 | DYRK3 | 1.62319826 |
| 22 | RPS6KA5 | 1.61666869 |
| 23 | NLK | 1.51589185 |
| 24 | IRAK2 | 1.47555464 |
| 25 | ADRBK2 | 1.47499657 |
| 26 | PKN1 | 1.43165504 |
| 27 | ABL2 | 1.41367325 |
| 28 | CDK9 | 1.30201828 |
| 29 | DYRK1B | 1.26595176 |
| 30 | MAP3K9 | 1.23480357 |
| 31 | KSR2 | 1.21192506 |
| 32 | DYRK1A | 1.19709878 |
| 33 | MAP3K14 | 1.18564835 |
| 34 | STK11 | 1.15805805 |
| 35 | NUAK1 | 1.14661852 |
| 36 | PRKAA1 | 1.13770727 |
| 37 | ATR | 1.09976315 |
| 38 | EPHB1 | 1.09890194 |
| 39 | SRPK1 | 1.08268968 |
| 40 | CSNK1G1 | 1.06123150 |
| 41 | VRK1 | 1.04749648 |
| 42 | CSNK1G3 | 1.03314702 |
| 43 | MKNK1 | 0.97717050 |
| 44 | MAP4K2 | 0.96291114 |
| 45 | DYRK2 | 0.91309631 |
| 46 | MAP3K13 | 0.87307968 |
| 47 | SIK1 | 0.85492658 |
| 48 | BCKDK | 0.80536266 |
| 49 | PIM1 | 0.80134411 |
| 50 | CSNK1G2 | 0.77570634 |
| 51 | IKBKE | 0.77264118 |
| 52 | BMPR1B | 0.75502247 |
| 53 | CAMK1D | 0.75160909 |
| 54 | PIK3CG | 0.72305560 |
| 55 | ERBB3 | 0.70612151 |
| 56 | TAOK1 | 0.70375544 |
| 57 | RPS6KA1 | 0.68751704 |
| 58 | TRPM7 | 0.66532041 |
| 59 | FGFR3 | 0.66047137 |
| 60 | CAMK1 | 0.65913428 |
| 61 | BRD4 | 0.65253316 |
| 62 | STK4 | 0.61546870 |
| 63 | EIF2AK3 | 0.57838732 |
| 64 | ARAF | 0.57105770 |
| 65 | STK38L | 0.56878006 |
| 66 | BRAF | 0.55943696 |
| 67 | WNK3 | 0.55879307 |
| 68 | MAP2K1 | 0.55339299 |
| 69 | TYRO3 | 0.55189211 |
| 70 | ATM | 0.53922251 |
| 71 | STK3 | 0.53821699 |
| 72 | GRK1 | 0.51196411 |
| 73 | ERBB2 | 0.49117823 |
| 74 | EPHA4 | 0.47485566 |
| 75 | WNK1 | 0.45661861 |
| 76 | LATS1 | 0.44057181 |
| 77 | MAPK11 | 0.43029711 |
| 78 | MAP3K8 | 0.41449800 |
| 79 | PAK6 | 0.41409179 |
| 80 | TEC | 0.41273406 |
| 81 | PAK1 | 0.40418123 |
| 82 | TXK | 0.39383878 |
| 83 | MUSK | 0.39139945 |
| 84 | CSNK1E | 0.37316802 |
| 85 | OXSR1 | 0.35727152 |
| 86 | ADRBK1 | 0.35267542 |
| 87 | DAPK2 | 0.35018920 |
| 88 | AURKB | 0.34728423 |
| 89 | CSNK1A1L | 0.34406677 |
| 90 | PRKG1 | 0.33155885 |
| 91 | RAF1 | 0.30981338 |
| 92 | MINK1 | 0.29387936 |
| 93 | JAK2 | 0.29114164 |
| 94 | CSNK1D | 0.28923649 |
| 95 | PAK3 | 0.28806061 |
| 96 | PRKCI | 0.28694247 |
| 97 | TAOK3 | 0.27491902 |
| 98 | MAPK1 | 0.27475479 |
| 99 | TIE1 | 0.25590039 |
| 100 | CHEK1 | 0.24786763 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 8.14152714 |
| 2 | Alcoholism_Homo sapiens_hsa05034 | 5.40530743 |
| 3 | Viral carcinogenesis_Homo sapiens_hsa05203 | 3.49799683 |
| 4 | Fatty acid elongation_Homo sapiens_hsa00062 | 2.95070610 |
| 5 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 2.76363465 |
| 6 | Nitrogen metabolism_Homo sapiens_hsa00910 | 2.45651860 |
| 7 | Allograft rejection_Homo sapiens_hsa05330 | 2.40986617 |
| 8 | Graft-versus-host disease_Homo sapiens_hsa05332 | 2.38858424 |
| 9 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.09099006 |
| 10 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 2.01847202 |
| 11 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 2.01735830 |
| 12 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.99335438 |
| 13 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 1.74965443 |
| 14 | Circadian rhythm_Homo sapiens_hsa04710 | 1.50726099 |
| 15 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.50514993 |
| 16 | ABC transporters_Homo sapiens_hsa02010 | 1.49585505 |
| 17 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.43661467 |
| 18 | Asthma_Homo sapiens_hsa05310 | 1.40382934 |
| 19 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.39821011 |
| 20 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 1.38950548 |
| 21 | p53 signaling pathway_Homo sapiens_hsa04115 | 1.38002023 |
| 22 | RNA polymerase_Homo sapiens_hsa03020 | 1.29926410 |
| 23 | Taste transduction_Homo sapiens_hsa04742 | 1.26960631 |
| 24 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 1.19726536 |
| 25 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 1.14887823 |
| 26 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 1.13293209 |
| 27 | Olfactory transduction_Homo sapiens_hsa04740 | 1.11548276 |
| 28 | Proteasome_Homo sapiens_hsa03050 | 1.09871903 |
| 29 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.08975089 |
| 30 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.08127822 |
| 31 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.07868385 |
| 32 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.02118163 |
| 33 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.01013196 |
| 34 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.00648680 |
| 35 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.99364882 |
| 36 | Lysine degradation_Homo sapiens_hsa00310 | 0.96702360 |
| 37 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.86734633 |
| 38 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.84215836 |
| 39 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.83116708 |
| 40 | Viral myocarditis_Homo sapiens_hsa05416 | 0.83009754 |
| 41 | Phototransduction_Homo sapiens_hsa04744 | 0.81733295 |
| 42 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.74225320 |
| 43 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.73505716 |
| 44 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.73332763 |
| 45 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.73235863 |
| 46 | Basal transcription factors_Homo sapiens_hsa03022 | 0.71761837 |
| 47 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.71697374 |
| 48 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.71390236 |
| 49 | Legionellosis_Homo sapiens_hsa05134 | 0.68182823 |
| 50 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.68024576 |
| 51 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.67510164 |
| 52 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.65955871 |
| 53 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.63182419 |
| 54 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.62785637 |
| 55 | Leishmaniasis_Homo sapiens_hsa05140 | 0.62191994 |
| 56 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.59385303 |
| 57 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.56157557 |
| 58 | Homologous recombination_Homo sapiens_hsa03440 | 0.53231922 |
| 59 | DNA replication_Homo sapiens_hsa03030 | 0.50645228 |
| 60 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.50038453 |
| 61 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.48784928 |
| 62 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 0.47756311 |
| 63 | Phagosome_Homo sapiens_hsa04145 | 0.47479552 |
| 64 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.46369497 |
| 65 | Purine metabolism_Homo sapiens_hsa00230 | 0.45709228 |
| 66 | Protein digestion and absorption_Homo sapiens_hsa04974 | 0.45233561 |
| 67 | Protein export_Homo sapiens_hsa03060 | 0.42431255 |
| 68 | RNA transport_Homo sapiens_hsa03013 | 0.41696617 |
| 69 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.40415736 |
| 70 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.37933963 |
| 71 | Bile secretion_Homo sapiens_hsa04976 | 0.37087273 |
| 72 | Retinol metabolism_Homo sapiens_hsa00830 | 0.36711927 |
| 73 | Malaria_Homo sapiens_hsa05144 | 0.35967964 |
| 74 | Salivary secretion_Homo sapiens_hsa04970 | 0.34702480 |
| 75 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.33543614 |
| 76 | Morphine addiction_Homo sapiens_hsa05032 | 0.33536737 |
| 77 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.32999274 |
| 78 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.32726704 |
| 79 | Nicotine addiction_Homo sapiens_hsa05033 | 0.31992134 |
| 80 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.31017287 |
| 81 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.30717640 |
| 82 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.28181296 |
| 83 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.26997016 |
| 84 | Peroxisome_Homo sapiens_hsa04146 | 0.24018632 |
| 85 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.23974847 |
| 86 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.22505849 |
| 87 | Circadian entrainment_Homo sapiens_hsa04713 | 0.21999211 |
| 88 | Sulfur relay system_Homo sapiens_hsa04122 | 0.21990697 |
| 89 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.21827196 |
| 90 | Long-term depression_Homo sapiens_hsa04730 | 0.21755701 |
| 91 | Tuberculosis_Homo sapiens_hsa05152 | 0.21741901 |
| 92 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.20464622 |
| 93 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.19857748 |
| 94 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.19556776 |
| 95 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.19454286 |
| 96 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.18161981 |
| 97 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.17602144 |
| 98 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.17270814 |
| 99 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.16106385 |
| 100 | Spliceosome_Homo sapiens_hsa03040 | 0.14716988 |

