Rank | Gene Set | Z-score |
---|---|---|
1 | nuclear pore complex assembly (GO:0051292) | 5.99039704 |
2 | nuclear pore organization (GO:0006999) | 5.74998911 |
3 | centriole replication (GO:0007099) | 5.43056752 |
4 | pore complex assembly (GO:0046931) | 4.70377063 |
5 | mitotic sister chromatid cohesion (GO:0007064) | 4.57067129 |
6 | regulation of helicase activity (GO:0051095) | 4.31800885 |
7 | response to pheromone (GO:0019236) | 4.20860973 |
8 | regulation of centriole replication (GO:0046599) | 4.15427694 |
9 | neural tube formation (GO:0001841) | 4.12736489 |
10 | regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266) | 4.03248219 |
11 | regulation of mitotic spindle checkpoint (GO:1903504) | 4.03248219 |
12 | protein localization to kinetochore (GO:0034501) | 4.01296421 |
13 | mitotic nuclear envelope disassembly (GO:0007077) | 3.97097600 |
14 | histone mRNA catabolic process (GO:0071044) | 3.97081198 |
15 | mitotic metaphase plate congression (GO:0007080) | 3.93362624 |
16 | DNA replication initiation (GO:0006270) | 3.89990828 |
17 | DNA unwinding involved in DNA replication (GO:0006268) | 3.87789491 |
18 | histone H2A acetylation (GO:0043968) | 3.81476116 |
19 | maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005) | 3.81201601 |
20 | DNA strand elongation involved in DNA replication (GO:0006271) | 3.79076249 |
21 | DNA strand elongation (GO:0022616) | 3.77945753 |
22 | microtubule depolymerization (GO:0007019) | 3.75783751 |
23 | replication fork processing (GO:0031297) | 3.74303987 |
24 | pre-miRNA processing (GO:0031054) | 3.73646005 |
25 | membrane disassembly (GO:0030397) | 3.70304803 |
26 | nuclear envelope disassembly (GO:0051081) | 3.70304803 |
27 | protein localization to chromosome, centromeric region (GO:0071459) | 3.68412934 |
28 | spermatid nucleus differentiation (GO:0007289) | 3.64819563 |
29 | cellular response to interleukin-15 (GO:0071350) | 3.64311639 |
30 | acrosome reaction (GO:0007340) | 3.64015299 |
31 | kinetochore organization (GO:0051383) | 3.62856773 |
32 | rRNA methylation (GO:0031167) | 3.61624372 |
33 | DNA replication-dependent nucleosome assembly (GO:0006335) | 3.60364201 |
34 | DNA replication-dependent nucleosome organization (GO:0034723) | 3.60364201 |
35 | regulation of nuclear cell cycle DNA replication (GO:0033262) | 3.60284120 |
36 | telomere maintenance via semi-conservative replication (GO:0032201) | 3.56644519 |
37 | regulation of histone H3-K9 methylation (GO:0051570) | 3.55678657 |
38 | negative regulation of DNA-dependent DNA replication (GO:2000104) | 3.54076019 |
39 | DNA double-strand break processing (GO:0000729) | 3.49037051 |
40 | centriole assembly (GO:0098534) | 3.48857591 |
41 | peptidyl-lysine trimethylation (GO:0018023) | 3.48164367 |
42 | DNA geometric change (GO:0032392) | 3.48004701 |
43 | telomere maintenance via recombination (GO:0000722) | 3.47540798 |
44 | sister chromatid segregation (GO:0000819) | 3.47418558 |
45 | negative regulation of histone methylation (GO:0031061) | 3.46913663 |
46 | sperm motility (GO:0030317) | 3.44743197 |
47 | regulation of attachment of spindle microtubules to kinetochore (GO:0051988) | 3.44270866 |
48 | mismatch repair (GO:0006298) | 3.43994748 |
49 | metaphase plate congression (GO:0051310) | 3.43230123 |
50 | mitotic recombination (GO:0006312) | 3.42824401 |
51 | microtubule polymerization or depolymerization (GO:0031109) | 3.42727429 |
52 | telomere maintenance via telomerase (GO:0007004) | 3.40220710 |
53 | meiotic chromosome segregation (GO:0045132) | 3.40174210 |
54 | DNA duplex unwinding (GO:0032508) | 3.40174057 |
55 | DNA replication-independent nucleosome organization (GO:0034724) | 3.39260665 |
56 | DNA replication-independent nucleosome assembly (GO:0006336) | 3.39260665 |
57 | mitotic sister chromatid segregation (GO:0000070) | 3.38927781 |
58 | DNA replication checkpoint (GO:0000076) | 3.36041207 |
59 | monoubiquitinated protein deubiquitination (GO:0035520) | 3.34194337 |
60 | regulation of telomere maintenance via telomerase (GO:0032210) | 3.33863636 |
61 | histone H3-K4 trimethylation (GO:0080182) | 3.32978249 |
62 | mitotic chromosome condensation (GO:0007076) | 3.31890175 |
63 | intra-S DNA damage checkpoint (GO:0031573) | 3.29619063 |
64 | negative regulation of DNA recombination (GO:0045910) | 3.29248819 |
65 | establishment of protein localization to Golgi (GO:0072600) | 3.28686084 |
66 | nucleotide-excision repair, DNA gap filling (GO:0006297) | 3.28312484 |
67 | chromatin remodeling at centromere (GO:0031055) | 3.28054844 |
68 | kinetochore assembly (GO:0051382) | 3.26667930 |
69 | dosage compensation (GO:0007549) | 3.23420737 |
70 | CENP-A containing nucleosome assembly (GO:0034080) | 3.23042056 |
71 | protein targeting to Golgi (GO:0000042) | 3.21188643 |
72 | translesion synthesis (GO:0019985) | 3.20380418 |
73 | sister chromatid cohesion (GO:0007062) | 3.18123900 |
74 | positive regulation of mitochondrial fission (GO:0090141) | 3.17585059 |
75 | telomere maintenance via telomere lengthening (GO:0010833) | 3.13740025 |
76 | regulation of spindle organization (GO:0090224) | 3.13246510 |
77 | IMP biosynthetic process (GO:0006188) | 3.12373854 |
78 | spindle checkpoint (GO:0031577) | 3.11888947 |
79 | postreplication repair (GO:0006301) | 3.11786078 |
80 | protein K11-linked deubiquitination (GO:0035871) | 3.11539819 |
81 | protein localization to chromosome (GO:0034502) | 3.10558236 |
82 | negative regulation of translation, ncRNA-mediated (GO:0040033) | 3.10030288 |
83 | regulation of translation, ncRNA-mediated (GO:0045974) | 3.10030288 |
84 | negative regulation of translation involved in gene silencing by miRNA (GO:0035278) | 3.10030288 |
85 | regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083) | 3.09229773 |
86 | ribosome assembly (GO:0042255) | 3.08407075 |
87 | chromatin assembly or disassembly (GO:0006333) | 3.03200309 |
88 | DNA strand renaturation (GO:0000733) | 3.02893108 |
89 | RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503) | 3.02872618 |
90 | histone mRNA metabolic process (GO:0008334) | 3.02484000 |
91 | histone H3-K9 methylation (GO:0051567) | 3.02257972 |
92 | positive regulation of chromosome segregation (GO:0051984) | 3.02017926 |
93 | regulation of DNA damage checkpoint (GO:2000001) | 3.01651348 |
94 | telomere organization (GO:0032200) | 3.01099518 |
95 | histone exchange (GO:0043486) | 3.00676416 |
96 | regulation of chromosome segregation (GO:0051983) | 3.00424016 |
97 | nucleobase biosynthetic process (GO:0046112) | 3.00379044 |
98 | spindle assembly checkpoint (GO:0071173) | 3.00186768 |
99 | telomere maintenance (GO:0000723) | 2.99826105 |
100 | response to interleukin-15 (GO:0070672) | 2.99692744 |
101 | negative regulation of chromosome segregation (GO:0051985) | 2.98534720 |
102 | negative regulation of mitotic sister chromatid separation (GO:2000816) | 2.98279739 |
103 | negative regulation of mitotic sister chromatid segregation (GO:0033048) | 2.98279739 |
104 | negative regulation of mitotic metaphase/anaphase transition (GO:0045841) | 2.98279739 |
105 | negative regulation of sister chromatid segregation (GO:0033046) | 2.98279739 |
106 | somatic hypermutation of immunoglobulin genes (GO:0016446) | 2.96565106 |
107 | somatic diversification of immune receptors via somatic mutation (GO:0002566) | 2.96565106 |
108 | double-strand break repair via homologous recombination (GO:0000724) | 2.95936491 |
109 | DNA-dependent DNA replication (GO:0006261) | 2.93304319 |
110 | mRNA transport (GO:0051028) | 2.93076699 |
111 | recombinational repair (GO:0000725) | 2.92589827 |
112 | regulation of mitotic metaphase/anaphase transition (GO:0030071) | 2.92334345 |
113 | microtubule nucleation (GO:0007020) | 2.92007233 |
114 | reciprocal DNA recombination (GO:0035825) | 2.91133177 |
115 | reciprocal meiotic recombination (GO:0007131) | 2.91133177 |
116 | establishment of chromosome localization (GO:0051303) | 2.91132641 |
117 | mitotic spindle assembly checkpoint (GO:0007094) | 2.91095548 |
118 | mitotic spindle checkpoint (GO:0071174) | 2.90035629 |
119 | ATP-dependent chromatin remodeling (GO:0043044) | 2.89897274 |
120 | DNA conformation change (GO:0071103) | 2.89617586 |
121 | histone H2A monoubiquitination (GO:0035518) | 2.88618198 |
122 | ribosome biogenesis (GO:0042254) | 2.88260936 |
123 | retrograde transport, vesicle recycling within Golgi (GO:0000301) | 2.87768055 |
124 | regulation of sister chromatid segregation (GO:0033045) | 2.87592272 |
125 | regulation of mitotic sister chromatid separation (GO:0010965) | 2.87592272 |
126 | regulation of mitotic sister chromatid segregation (GO:0033047) | 2.87592272 |
127 | attachment of spindle microtubules to kinetochore (GO:0008608) | 2.87479218 |
128 | mRNA export from nucleus (GO:0006406) | 2.87368069 |
129 | negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100) | 2.86282689 |
130 | negative regulation of mRNA splicing, via spliceosome (GO:0048025) | 2.85809555 |
131 | chromosome segregation (GO:0007059) | 2.85486100 |
132 | positive regulation of developmental pigmentation (GO:0048087) | 2.84247768 |
133 | prenylation (GO:0097354) | 2.76979553 |
134 | protein prenylation (GO:0018342) | 2.76979553 |
135 | rRNA modification (GO:0000154) | 2.75019380 |
136 | histone H3-K9 modification (GO:0061647) | 2.73909602 |
137 | mitotic G2 DNA damage checkpoint (GO:0007095) | 2.70922571 |
138 | positive regulation of mitotic sister chromatid separation (GO:1901970) | 2.65216256 |
139 | positive regulation of mitotic metaphase/anaphase transition (GO:0045842) | 2.65216256 |
140 | positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101) | 2.65216256 |
141 | regulation of alternative mRNA splicing, via spliceosome (GO:0000381) | 2.61851804 |
142 | positive regulation of granulocyte macrophage colony-stimulating factor production (GO:0032725) | 2.61388615 |
143 | phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092) | 2.61098640 |
144 | regulation of DNA endoreduplication (GO:0032875) | 2.59748015 |
145 | microtubule anchoring (GO:0034453) | 2.59600404 |
146 | regulation of centrosome duplication (GO:0010824) | 2.59581020 |
147 | synapsis (GO:0007129) | 2.58895645 |
148 | mitotic G2/M transition checkpoint (GO:0044818) | 2.58593548 |
149 | activated T cell proliferation (GO:0050798) | 2.56309112 |
150 | regulation of telomere maintenance (GO:0032204) | 2.50899742 |
151 | cellular response to ethanol (GO:0071361) | 2.50789067 |
152 | somatic diversification of immunoglobulins involved in immune response (GO:0002208) | 2.50748885 |
153 | isotype switching (GO:0045190) | 2.50748885 |
154 | somatic recombination of immunoglobulin genes involved in immune response (GO:0002204) | 2.50748885 |
155 | RNA destabilization (GO:0050779) | 2.49554077 |
156 | lymphoid progenitor cell differentiation (GO:0002320) | 2.48908223 |
157 | negative regulation of inclusion body assembly (GO:0090084) | 2.48425706 |
158 | somite development (GO:0061053) | 2.48085355 |
159 | regulation of DNA recombination (GO:0000018) | 2.47488359 |
160 | olfactory bulb development (GO:0021772) | 2.46426870 |
161 | regulation of nitric-oxide synthase biosynthetic process (GO:0051769) | 2.45493234 |
162 | spermatid development (GO:0007286) | 2.44813971 |
163 | regulation of meiosis I (GO:0060631) | 2.44611515 |
164 | pyrimidine dimer repair (GO:0006290) | 2.43856983 |
165 | regulation of metaphase/anaphase transition of cell cycle (GO:1902099) | 2.43339235 |
166 | DNA packaging (GO:0006323) | 2.42880084 |
167 | protein K48-linked deubiquitination (GO:0071108) | 2.41027970 |
168 | seminiferous tubule development (GO:0072520) | 2.40956456 |
169 | resolution of meiotic recombination intermediates (GO:0000712) | 2.40801221 |
170 | response to X-ray (GO:0010165) | 2.39780492 |
171 | mitochondrial fission (GO:0000266) | 2.38796411 |
Rank | Gene Set | Z-score |
---|---|---|
1 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 4.76141037 |
2 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 4.26033150 |
3 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 3.21959098 |
4 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 3.19050147 |
5 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 3.08593422 |
6 | * KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 3.05167036 |
7 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.83662793 |
8 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.81023923 |
9 | VDR_22108803_ChIP-Seq_LS180_Human | 2.67103740 |
10 | IGF1R_20145208_ChIP-Seq_DFB_Human | 2.64557723 |
11 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 2.57819017 |
12 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 2.57598700 |
13 | TAF15_26573619_Chip-Seq_HEK293_Human | 2.56339259 |
14 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 2.52415394 |
15 | * MYC_19030024_ChIP-ChIP_MESCs_Mouse | 2.47290812 |
16 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 2.43613059 |
17 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 2.40533140 |
18 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 2.39585690 |
19 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 2.35391558 |
20 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 2.34826473 |
21 | FUS_26573619_Chip-Seq_HEK293_Human | 2.30641297 |
22 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 2.29078164 |
23 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.27081223 |
24 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 2.24387926 |
25 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.24375838 |
26 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 2.14305797 |
27 | * E2F1_21310950_ChIP-Seq_MCF-7_Human | 2.12577320 |
28 | * MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.07509014 |
29 | * NELFA_20434984_ChIP-Seq_ESCs_Mouse | 2.05423219 |
30 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 2.05331079 |
31 | * MYC_18358816_ChIP-ChIP_MESCs_Mouse | 2.05067481 |
32 | E2F7_22180533_ChIP-Seq_HELA_Human | 10.3125947 |
33 | * VDR_23849224_ChIP-Seq_CD4+_Human | 1.99847660 |
34 | EWS_26573619_Chip-Seq_HEK293_Human | 1.99118603 |
35 | * MYC_22102868_ChIP-Seq_BL_Human | 1.97605343 |
36 | * MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.96212020 |
37 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.95901007 |
38 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 1.93646736 |
39 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.91865164 |
40 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.91176965 |
41 | * JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 1.90755203 |
42 | * ETS1_20019798_ChIP-Seq_JURKAT_Human | 1.88724195 |
43 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.87536025 |
44 | * XRN2_22483619_ChIP-Seq_HELA_Human | 1.87211699 |
45 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.87170325 |
46 | AR_21909140_ChIP-Seq_LNCAP_Human | 1.86963123 |
47 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.83639840 |
48 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.82147955 |
49 | * P300_19829295_ChIP-Seq_ESCs_Human | 1.81475572 |
50 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.78690614 |
51 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.75577033 |
52 | * THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.75419868 |
53 | * GABP_17652178_ChIP-ChIP_JURKAT_Human | 1.72338242 |
54 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.71482774 |
55 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.71211496 |
56 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.70478349 |
57 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.70478349 |
58 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.70347357 |
59 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.70050624 |
60 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.69410710 |
61 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.68463420 |
62 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.68176934 |
63 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.64526855 |
64 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.64128288 |
65 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.59456387 |
66 | SMAD1_18555785_ChIP-Seq_MESCs_Mouse | 1.58238130 |
67 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.57501830 |
68 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.55390635 |
69 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.54085214 |
70 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.53933978 |
71 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.51805350 |
72 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.50697129 |
73 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 1.49661089 |
74 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.48165482 |
75 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.47272870 |
76 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.45579386 |
77 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.45579386 |
78 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.45131870 |
79 | * GABP_19822575_ChIP-Seq_HepG2_Human | 1.44989795 |
80 | KDM5A_27292631_Chip-Seq_BREAST_Human | 1.44542848 |
81 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 1.44016187 |
82 | * HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.42776050 |
83 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 1.42737989 |
84 | * TTF2_22483619_ChIP-Seq_HELA_Human | 1.42125261 |
85 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.40098846 |
86 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.40017747 |
87 | * HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.39429272 |
88 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.39084768 |
89 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.36623142 |
90 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.35733609 |
91 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.32580559 |
92 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.32466891 |
93 | * DCP1A_22483619_ChIP-Seq_HELA_Human | 1.30104946 |
94 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.28571099 |
95 | * CREM_20920259_ChIP-Seq_GC1-SPG_Mouse | 1.27339052 |
96 | * MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 1.26148739 |
97 | * TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.25114967 |
98 | * CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat | 1.23748606 |
99 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.23066303 |
100 | * SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.22206104 |
101 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.21869414 |
102 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 1.21466840 |
103 | * SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.21217543 |
104 | GATA3_26560356_Chip-Seq_TH2_Human | 1.20670206 |
105 | * RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse | 1.20654218 |
106 | ZFX_18555785_ChIP-Seq_MESCs_Mouse | 1.18556882 |
107 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.18357561 |
108 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 1.18264879 |
109 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.18072258 |
110 | SOX2_19030024_ChIP-ChIP_MESCs_Mouse | 1.17570212 |
111 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 1.16333591 |
112 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.16202272 |
113 | STAT3_23295773_ChIP-Seq_U87_Human | 1.15462238 |
114 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 1.15266309 |
115 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.14514567 |
116 | RUNX_20019798_ChIP-Seq_JUKART_Human | 1.14474567 |
117 | RUNX1_17652178_ChIP-ChIP_JURKAT_Human | 1.13135000 |
118 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 1.12036729 |
119 | * CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 1.11774474 |
120 | AR_25329375_ChIP-Seq_VCAP_Human | 1.11659670 |
121 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.10318023 |
122 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.10318023 |
123 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.09731640 |
124 | SALL4_22934838_ChIP-ChIP_CD34+_Human | 1.09531441 |
125 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.09035385 |
126 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.09016150 |
127 | * E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 1.07349140 |
128 | TCF4_23295773_ChIP-Seq_U87_Human | 1.07180360 |
129 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 1.06867857 |
130 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.06374889 |
131 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.05986844 |
132 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.05720386 |
133 | * FOXA1_21572438_ChIP-Seq_LNCaP_Human | 1.05019514 |
134 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 1.04985281 |
135 | SUZ12_18555785_Chip-Seq_ESCs_Mouse | 1.04916337 |
136 | RUNX2_22187159_ChIP-Seq_PCA_Human | 1.04610920 |
137 | VDR_24787735_ChIP-Seq_THP-1_Human | 1.04049942 |
138 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.03979580 |
139 | P300_18555785_Chip-Seq_ESCs_Mouse | 1.03203939 |
140 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.02983977 |
141 | TCF4_22108803_ChIP-Seq_LS180_Human | 1.02618753 |
142 | PRDM5_23873026_ChIP-Seq_MEFs_Mouse | 1.02551346 |
143 | E2F1_18555785_Chip-Seq_ESCs_Mouse | 1.02283148 |
144 | P53_22387025_ChIP-Seq_ESCs_Mouse | 1.02132804 |
145 | SALL4_18804426_ChIP-ChIP_MESCs_Mouse | 1.02088859 |
146 | * ERG_20887958_ChIP-Seq_HPC-7_Mouse | 1.01990432 |
147 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.01524272 |
148 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.01361887 |
149 | * NANOG_21062744_ChIP-ChIP_HESCs_Human | 1.00967957 |
150 | GATA3_26560356_Chip-Seq_TH1_Human | 1.00360922 |
151 | * SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 0.98568710 |
152 | TFEB_21752829_ChIP-Seq_HELA_Human | 0.97958398 |
153 | HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse | 0.96985441 |
154 | * CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse | 0.96787705 |
155 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 0.94059717 |
156 | * KLF4_18555785_ChIP-Seq_MESCs_Mouse | 0.93820050 |
157 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 0.93789933 |
158 | CNOT3_19339689_ChIP-ChIP_MESCs_Mouse | 0.92845993 |
159 | NANOG_18358816_ChIP-ChIP_MESCs_Mouse | 0.91870312 |
160 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 0.90400662 |
161 | TCF3_18692474_ChIP-Seq_MESCs_Mouse | 0.90142487 |
162 | * FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.90095833 |
163 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 0.89757926 |
164 | * GFI1B_20887958_ChIP-Seq_HPC-7_Mouse | 0.89597837 |
165 | NACC1_18358816_ChIP-ChIP_MESCs_Mouse | 0.88785447 |
166 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 0.87172984 |
167 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 0.85948693 |
168 | MYB_26560356_Chip-Seq_TH2_Human | 0.81293358 |
169 | DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 0.80564923 |
170 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 0.79064660 |
171 | KLF2_18264089_ChIP-ChIP_MESCs_Mouse | 0.78855862 |
172 | KLF5_18264089_ChIP-ChIP_MESCs_Mouse | 0.78855862 |
173 | KLF4_18264089_ChIP-ChIP_MESCs_Mouse | 0.78855862 |
174 | MYC_18940864_ChIP-ChIP_HL60_Human | 0.78794101 |
175 | MYB_26560356_Chip-Seq_TH1_Human | 0.78616034 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0010094_abnormal_chromosome_stability | 4.77278783 |
2 | MP0008057_abnormal_DNA_replication | 4.40732127 |
3 | MP0003111_abnormal_nucleus_morphology | 4.15238308 |
4 | MP0003693_abnormal_embryo_hatching | 3.96483337 |
5 | MP0003077_abnormal_cell_cycle | 3.54215583 |
6 | MP0008058_abnormal_DNA_repair | 3.51378732 |
7 | MP0004957_abnormal_blastocyst_morpholog | 3.37103192 |
8 | MP0008007_abnormal_cellular_replicative | 2.85231667 |
9 | MP0008877_abnormal_DNA_methylation | 2.51924756 |
10 | MP0005410_abnormal_fertilization | 2.43626343 |
11 | MP0003221_abnormal_cardiomyocyte_apopto | 2.38776658 |
12 | MP0002653_abnormal_ependyma_morphology | 2.18534906 |
13 | MP0003787_abnormal_imprinting | 2.17964869 |
14 | MP0001835_abnormal_antigen_presentation | 2.14641149 |
15 | MP0003121_genomic_imprinting | 2.14123228 |
16 | MP0000350_abnormal_cell_proliferation | 2.12411115 |
17 | MP0002396_abnormal_hematopoietic_system | 2.12357617 |
18 | MP0003724_increased_susceptibility_to | 2.02208402 |
19 | MP0001730_embryonic_growth_arrest | 1.98836921 |
20 | MP0005367_renal/urinary_system_phenotyp | 1.96232618 |
21 | MP0000516_abnormal_urinary_system | 1.96232618 |
22 | MP0003890_abnormal_embryonic-extraembry | 1.95641861 |
23 | MP0008932_abnormal_embryonic_tissue | 1.90880699 |
24 | MP0003123_paternal_imprinting | 1.85579377 |
25 | MP0010307_abnormal_tumor_latency | 1.80658560 |
26 | MP0004808_abnormal_hematopoietic_stem | 1.79529345 |
27 | MP0001672_abnormal_embryogenesis/_devel | 1.73131495 |
28 | MP0005380_embryogenesis_phenotype | 1.73131495 |
29 | MP0000465_gastrointestinal_hemorrhage | 1.69876658 |
30 | MP0000569_abnormal_digit_pigmentation | 1.69532923 |
31 | MP0002085_abnormal_embryonic_tissue | 1.67620318 |
32 | MP0001697_abnormal_embryo_size | 1.63725561 |
33 | MP0002084_abnormal_developmental_patter | 1.62631891 |
34 | MP0003763_abnormal_thymus_physiology | 1.61138564 |
35 | MP0004197_abnormal_fetal_growth/weight/ | 1.59508790 |
36 | MP0003984_embryonic_growth_retardation | 1.57658161 |
37 | MP0003786_premature_aging | 1.57009733 |
38 | MP0002088_abnormal_embryonic_growth/wei | 1.55125546 |
39 | MP0006292_abnormal_olfactory_placode | 1.50704531 |
40 | MP0000703_abnormal_thymus_morphology | 1.49909332 |
41 | MP0005076_abnormal_cell_differentiation | 1.49236886 |
42 | MP0009697_abnormal_copulation | 1.47490480 |
43 | MP0005253_abnormal_eye_physiology | 1.45156463 |
44 | MP0001986_abnormal_taste_sensitivity | 1.43359183 |
45 | MP0005310_abnormal_salivary_gland | 1.39182283 |
46 | MP0002210_abnormal_sex_determination | 1.38616753 |
47 | MP0002086_abnormal_extraembryonic_tissu | 1.38538250 |
48 | MP0003880_abnormal_central_pattern | 1.38005628 |
49 | MP0002080_prenatal_lethality | 1.36678172 |
50 | MP0009764_decreased_sensitivity_to | 1.35786767 |
51 | MP0005084_abnormal_gallbladder_morpholo | 1.34910372 |
52 | MP0000490_abnormal_crypts_of | 1.34383791 |
53 | MP0010352_gastrointestinal_tract_polyps | 1.33774698 |
54 | MP0002009_preneoplasia | 1.28527068 |
55 | MP0000313_abnormal_cell_death | 1.27578709 |
56 | MP0003315_abnormal_perineum_morphology | 1.24354925 |
57 | MP0002723_abnormal_immune_serum | 1.22307294 |
58 | MP0005248_abnormal_Harderian_gland | 1.22121547 |
59 | MP0000015_abnormal_ear_pigmentation | 1.20482660 |
60 | MP0002452_abnormal_antigen_presenting | 1.20252935 |
61 | MP0008995_early_reproductive_senescence | 1.19911866 |
62 | MP0000372_irregular_coat_pigmentation | 1.18559844 |
63 | MP0005000_abnormal_immune_tolerance | 1.17901442 |
64 | MP0001929_abnormal_gametogenesis | 1.17648987 |
65 | MP0002398_abnormal_bone_marrow | 1.16724006 |
66 | MP0003136_yellow_coat_color | 1.16131023 |
67 | MP0003656_abnormal_erythrocyte_physiolo | 1.15946718 |
68 | MP0002019_abnormal_tumor_incidence | 1.14351780 |
69 | MP0001145_abnormal_male_reproductive | 1.13415861 |
70 | MP0000566_synostosis | 1.11043056 |
71 | MP0002420_abnormal_adaptive_immunity | 1.09382625 |
72 | MP0000383_abnormal_hair_follicle | 1.09374505 |
73 | MP0003646_muscle_fatigue | 1.08855412 |
74 | MP0001819_abnormal_immune_cell | 1.07395705 |
75 | MP0010678_abnormal_skin_adnexa | 1.04345550 |
76 | MP0004133_heterotaxia | 1.04140630 |
77 | MP0002102_abnormal_ear_morphology | 1.03388193 |
78 | MP0001293_anophthalmia | 1.03205846 |
79 | MP0004484_altered_response_of | 1.03104439 |
80 | MP0002938_white_spotting | 1.02235209 |
81 | MP0002095_abnormal_skin_pigmentation | 1.02058695 |
82 | MP0003119_abnormal_digestive_system | 1.00659384 |
83 | MP0000653_abnormal_sex_gland | 0.99061438 |
84 | MP0009703_decreased_birth_body | 0.98564661 |
85 | MP0002722_abnormal_immune_system | 0.98517206 |
86 | MP0003937_abnormal_limbs/digits/tail_de | 0.97663579 |
87 | MP0000537_abnormal_urethra_morphology | 0.96787542 |
88 | MP0000427_abnormal_hair_cycle | 0.96488072 |
89 | MP0002751_abnormal_autonomic_nervous | 0.96314033 |
90 | MP0001324_abnormal_eye_pigmentation | 0.95909577 |
91 | MP0005670_abnormal_white_adipose | 0.94494454 |
92 | MP0001119_abnormal_female_reproductive | 0.94245359 |
93 | MP0009672_abnormal_birth_weight | 0.93932506 |
94 | MP0009785_altered_susceptibility_to | 0.92333448 |
95 | MP0004381_abnormal_hair_follicle | 0.92126789 |
96 | MP0002132_abnormal_respiratory_system | 0.91960954 |
97 | MP0001286_abnormal_eye_development | 0.91919869 |
98 | MP0005174_abnormal_tail_pigmentation | 0.91862776 |
99 | MP0003567_abnormal_fetal_cardiomyocyte | 0.90893829 |
100 | MP0000689_abnormal_spleen_morphology | 0.90372227 |
101 | MP0009765_abnormal_xenobiotic_induced | 0.89634590 |
102 | MP0005377_hearing/vestibular/ear_phenot | 0.89535745 |
103 | MP0003878_abnormal_ear_physiology | 0.89535745 |
104 | MP0010030_abnormal_orbit_morphology | 0.89041395 |
105 | MP0002928_abnormal_bile_duct | 0.88600393 |
106 | MP0002075_abnormal_coat/hair_pigmentati | 0.88286843 |
107 | MP0004264_abnormal_extraembryonic_tissu | 0.86215131 |
108 | MP0005395_other_phenotype | 0.86078941 |
109 | MP0003941_abnormal_skin_development | 0.85372758 |
110 | MP0008789_abnormal_olfactory_epithelium | 0.84361872 |
111 | MP0001915_intracranial_hemorrhage | 0.84113077 |
112 | MP0003861_abnormal_nervous_system | 0.83980378 |
113 | MP0001486_abnormal_startle_reflex | 0.83155592 |
114 | MP0005391_vision/eye_phenotype | 0.82801036 |
115 | MP0002160_abnormal_reproductive_system | 0.82428651 |
116 | MP0000428_abnormal_craniofacial_morphol | 0.82405276 |
117 | MP0003698_abnormal_male_reproductive | 0.81725208 |
118 | MP0009333_abnormal_splenocyte_physiolog | 0.81247240 |
119 | MP0000778_abnormal_nervous_system | 0.79707087 |
120 | MP0002419_abnormal_innate_immunity | 0.79627587 |
121 | MP0003943_abnormal_hepatobiliary_system | 0.78457244 |
122 | MP0001529_abnormal_vocalization | 0.77709919 |
123 | MP0003115_abnormal_respiratory_system | 0.77318109 |
124 | MP0002282_abnormal_trachea_morphology | 0.75710030 |
125 | MP0002429_abnormal_blood_cell | 0.75284303 |
126 | MP0000371_diluted_coat_color | 0.74571787 |
127 | MP0003935_abnormal_craniofacial_develop | 0.72979118 |
128 | MP0000716_abnormal_immune_system | 0.72243795 |
129 | MP0001800_abnormal_humoral_immune | 0.71070739 |
130 | MP0006072_abnormal_retinal_apoptosis | 0.70514643 |
131 | MP0001853_heart_inflammation | 0.70425288 |
132 | MP0004742_abnormal_vestibular_system | 0.70330565 |
133 | MP0001188_hyperpigmentation | 0.70263252 |
134 | MP0000432_abnormal_head_morphology | 0.69751720 |
135 | MP0002148_abnormal_hypersensitivity_rea | 0.69015878 |
136 | MP0003718_maternal_effect | 0.68889305 |
137 | MP0001186_pigmentation_phenotype | 0.68198952 |
138 | MP0002277_abnormal_respiratory_mucosa | 0.68051340 |
139 | MP0005075_abnormal_melanosome_morpholog | 0.68040490 |
140 | MP0005397_hematopoietic_system_phenotyp | 0.67800968 |
141 | MP0001545_abnormal_hematopoietic_system | 0.67800968 |
142 | MP0002166_altered_tumor_susceptibility | 0.67614792 |
143 | MP0005671_abnormal_response_to | 0.67599491 |
144 | MP0002006_tumorigenesis | 0.67083512 |
145 | MP0004215_abnormal_myocardial_fiber | 0.66449478 |
146 | MP0002735_abnormal_chemical_nociception | 0.66141301 |
147 | MP0005025_abnormal_response_to | 0.65972701 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Volvulus (HP:0002580) | 4.89204812 |
2 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 4.59804206 |
3 | Chromsome breakage (HP:0040012) | 4.48411686 |
4 | Tubulointerstitial nephritis (HP:0001970) | 4.00209118 |
5 | Chronic hepatic failure (HP:0100626) | 3.93762659 |
6 | Abnormality of the fingertips (HP:0001211) | 3.41578311 |
7 | Medulloblastoma (HP:0002885) | 3.40890216 |
8 | Birth length less than 3rd percentile (HP:0003561) | 3.38619738 |
9 | Abnormality of chromosome stability (HP:0003220) | 3.26773807 |
10 | Ependymoma (HP:0002888) | 3.16310602 |
11 | Abnormality of the ileum (HP:0001549) | 3.08919241 |
12 | Ectopic kidney (HP:0000086) | 2.96874331 |
13 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 2.94230929 |
14 | Neoplasm of the oral cavity (HP:0100649) | 2.89697664 |
15 | Meckel diverticulum (HP:0002245) | 2.86607665 |
16 | Selective tooth agenesis (HP:0001592) | 2.83230722 |
17 | Patellar aplasia (HP:0006443) | 2.74904327 |
18 | Abnormality of the labia minora (HP:0012880) | 2.74047309 |
19 | Abnormality of the preputium (HP:0100587) | 2.69838242 |
20 | Impulsivity (HP:0100710) | 2.69786494 |
21 | Aplasia/Hypoplasia of the tibia (HP:0005772) | 2.69078268 |
22 | Abnormal number of incisors (HP:0011064) | 2.67902370 |
23 | Short tibia (HP:0005736) | 2.65707501 |
24 | Abnormal hair whorl (HP:0010721) | 2.64386669 |
25 | Amaurosis fugax (HP:0100576) | 2.60714666 |
26 | Supernumerary spleens (HP:0009799) | 2.59378374 |
27 | Prominent nose (HP:0000448) | 2.57762844 |
28 | Glioma (HP:0009733) | 2.56312325 |
29 | Intestinal atresia (HP:0011100) | 2.54416351 |
30 | Myelodysplasia (HP:0002863) | 2.49390854 |
31 | Long eyelashes (HP:0000527) | 2.48752906 |
32 | Increased nuchal translucency (HP:0010880) | 2.48392329 |
33 | Aplasia/Hypoplasia of the patella (HP:0006498) | 2.48165343 |
34 | 11 pairs of ribs (HP:0000878) | 2.46346048 |
35 | Astrocytoma (HP:0009592) | 2.45516950 |
36 | Abnormality of the astrocytes (HP:0100707) | 2.45516950 |
37 | Abnormality of the carotid arteries (HP:0005344) | 2.40971411 |
38 | Sloping forehead (HP:0000340) | 2.39492205 |
39 | Nephroblastoma (Wilms tumor) (HP:0002667) | 2.38661590 |
40 | Papillary thyroid carcinoma (HP:0002895) | 2.36206794 |
41 | Abnormality of lateral ventricle (HP:0030047) | 2.35345445 |
42 | Colon cancer (HP:0003003) | 2.33609477 |
43 | Small intestinal stenosis (HP:0012848) | 2.31319086 |
44 | Duodenal stenosis (HP:0100867) | 2.31319086 |
45 | Bone marrow hypocellularity (HP:0005528) | 2.30635343 |
46 | Stomatitis (HP:0010280) | 2.30463465 |
47 | Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042) | 2.29647498 |
48 | Short 4th metacarpal (HP:0010044) | 2.29647498 |
49 | Optic nerve coloboma (HP:0000588) | 2.29585059 |
50 | High anterior hairline (HP:0009890) | 2.29476504 |
51 | Broad alveolar ridges (HP:0000187) | 2.28379660 |
52 | Neoplasm of the pancreas (HP:0002894) | 2.25788741 |
53 | Albinism (HP:0001022) | 2.24947521 |
54 | Aplasia/Hypoplasia of the sternum (HP:0006714) | 2.24935085 |
55 | Pancreatic cysts (HP:0001737) | 2.22502796 |
56 | T lymphocytopenia (HP:0005403) | 2.21655037 |
57 | Embryonal renal neoplasm (HP:0011794) | 2.20298855 |
58 | Absent speech (HP:0001344) | 2.17820096 |
59 | Lip pit (HP:0100267) | 2.13754554 |
60 | Deep philtrum (HP:0002002) | 2.13641919 |
61 | Proximal placement of thumb (HP:0009623) | 2.13423129 |
62 | Atrophy/Degeneration involving the corticospinal tracts (HP:0007372) | 2.12077600 |
63 | Degeneration of the lateral corticospinal tracts (HP:0002314) | 2.12077600 |
64 | Tented upper lip vermilion (HP:0010804) | 2.11715014 |
65 | Facial hemangioma (HP:0000329) | 2.08691900 |
66 | Thyroid carcinoma (HP:0002890) | 2.07889276 |
67 | Recurrent cutaneous fungal infections (HP:0011370) | 2.05880173 |
68 | Chronic mucocutaneous candidiasis (HP:0002728) | 2.05880173 |
69 | Bony spicule pigmentary retinopathy (HP:0007737) | 2.05042684 |
70 | Capillary hemangiomas (HP:0005306) | 2.04766817 |
71 | Dyschromatopsia (HP:0007641) | 2.03490592 |
72 | Abnormality of the duodenum (HP:0002246) | 2.02810916 |
73 | Deviation of the thumb (HP:0009603) | 2.01388512 |
74 | Clitoromegaly (HP:0000057) | 2.01089204 |
75 | Tubulointerstitial abnormality (HP:0001969) | 2.00814841 |
76 | Neoplasm of the tracheobronchial system (HP:0100552) | 2.00634220 |
77 | Oligodactyly (hands) (HP:0001180) | 1.99945640 |
78 | Basal cell carcinoma (HP:0002671) | 1.99772261 |
79 | Premature graying of hair (HP:0002216) | 1.98669593 |
80 | Abnormality of T cell number (HP:0011839) | 1.98202028 |
81 | Degeneration of anterior horn cells (HP:0002398) | 1.97829189 |
82 | Abnormality of the anterior horn cell (HP:0006802) | 1.97829189 |
83 | Acute myeloid leukemia (HP:0004808) | 1.97508722 |
84 | Stomach cancer (HP:0012126) | 1.97060400 |
85 | Cafe-au-lait spot (HP:0000957) | 1.95939771 |
86 | Abnormality of B cell number (HP:0010975) | 1.95936552 |
87 | B lymphocytopenia (HP:0010976) | 1.95936552 |
88 | Clubbing of toes (HP:0100760) | 1.94837267 |
89 | Progressive cerebellar ataxia (HP:0002073) | 1.94102787 |
90 | Renal cortical cysts (HP:0000803) | 1.93976083 |
91 | Rhabdomyosarcoma (HP:0002859) | 1.93550607 |
92 | Cellular immunodeficiency (HP:0005374) | 1.91321580 |
93 | Panhypogammaglobulinemia (HP:0003139) | 1.91163187 |
94 | Cone-rod dystrophy (HP:0000548) | 1.90893128 |
95 | Agnosia (HP:0010524) | 1.90740762 |
96 | Abnormality of the renal cortex (HP:0011035) | 1.89609619 |
97 | Urethral obstruction (HP:0000796) | 1.89008986 |
98 | Abnormality of the intervertebral disk (HP:0005108) | 1.87776684 |
99 | Cupped ear (HP:0000378) | 1.87611148 |
100 | Short thumb (HP:0009778) | 1.87403950 |
101 | Hematochezia (HP:0002573) | 1.87396592 |
102 | Abnormality of DNA repair (HP:0003254) | 1.86515290 |
103 | Neoplasm of striated muscle (HP:0009728) | 1.85635038 |
104 | Curly hair (HP:0002212) | 1.85565104 |
105 | Severe combined immunodeficiency (HP:0004430) | 1.85202144 |
106 | Pancreatic fibrosis (HP:0100732) | 1.84579280 |
107 | Pendular nystagmus (HP:0012043) | 1.84103774 |
108 | Lymphoma (HP:0002665) | 1.83581850 |
109 | Duplicated collecting system (HP:0000081) | 1.81928122 |
110 | Heterotopia (HP:0002282) | 1.81227310 |
111 | Biliary tract neoplasm (HP:0100574) | 1.80556123 |
112 | Abnormal lung lobation (HP:0002101) | 1.80139453 |
113 | Dyskinesia (HP:0100660) | 1.79321934 |
114 | Broad palm (HP:0001169) | 1.79270187 |
115 | Absent radius (HP:0003974) | 1.78846851 |
116 | Acute lymphatic leukemia (HP:0006721) | 1.77362052 |
117 | Tracheoesophageal fistula (HP:0002575) | 1.77282682 |
118 | Abnormality of the renal collecting system (HP:0004742) | 1.76156891 |
119 | Neoplasm of the adrenal cortex (HP:0100641) | 1.76112626 |
120 | Alveolar cell carcinoma (HP:0006519) | 1.76011668 |
121 | Supernumerary ribs (HP:0005815) | 1.75970732 |
122 | Retrobulbar optic neuritis (HP:0100654) | 1.75708750 |
123 | Optic neuritis (HP:0100653) | 1.75708750 |
124 | Abnormality of eosinophils (HP:0001879) | 1.75111685 |
125 | Progressive inability to walk (HP:0002505) | 1.73536707 |
126 | Supernumerary bones of the axial skeleton (HP:0009144) | 1.73090843 |
127 | Attenuation of retinal blood vessels (HP:0007843) | 1.73087907 |
128 | Abnormality of chromosome segregation (HP:0002916) | 1.72982950 |
129 | Abnormality of the renal medulla (HP:0100957) | 1.72343459 |
130 | Cutis marmorata (HP:0000965) | 1.70853681 |
131 | Abnormality of T cells (HP:0002843) | 1.70179792 |
132 | Methylmalonic acidemia (HP:0002912) | 1.69878174 |
133 | Leukocytosis (HP:0001974) | 1.68244294 |
134 | Breast hypoplasia (HP:0003187) | 1.67010832 |
135 | Hypoplasia of the thymus (HP:0000778) | 1.66860624 |
136 | Nephronophthisis (HP:0000090) | 1.66829087 |
137 | Abnormality of midbrain morphology (HP:0002418) | 1.66810436 |
138 | Molar tooth sign on MRI (HP:0002419) | 1.66810436 |
139 | Thyroiditis (HP:0100646) | 1.66708347 |
140 | Oligodactyly (HP:0012165) | 1.66261360 |
141 | Genetic anticipation (HP:0003743) | 1.65991329 |
142 | Gastrointestinal atresia (HP:0002589) | 1.65371639 |
143 | Increased number of teeth (HP:0011069) | 1.65138236 |
144 | Absent forearm bone (HP:0003953) | 1.65048234 |
145 | Aplasia involving forearm bones (HP:0009822) | 1.65048234 |
146 | Truncal obesity (HP:0001956) | 1.63879571 |
147 | Chronic diarrhea (HP:0002028) | 1.63437587 |
148 | Hypochromic microcytic anemia (HP:0004840) | 1.63294883 |
149 | Combined immunodeficiency (HP:0005387) | 1.63141132 |
150 | Fibular hypoplasia (HP:0003038) | 1.62397907 |
151 | Gastrointestinal carcinoma (HP:0002672) | 1.61516829 |
152 | Malignant gastrointestinal tract tumors (HP:0006749) | 1.61516829 |
153 | Pancreatic islet-cell hyperplasia (HP:0004510) | 1.60645172 |
154 | Abnormality of the prostate (HP:0008775) | 1.59962290 |
155 | Hypoplastic labia majora (HP:0000059) | 1.58465262 |
156 | Severe visual impairment (HP:0001141) | 1.58168037 |
Rank | Gene Set | Z-score |
---|---|---|
1 | PASK | 4.54121013 |
2 | CDK12 | 3.58638250 |
3 | SRPK1 | 3.46224975 |
4 | CDC7 | 3.45979239 |
5 | WNK3 | 3.33997668 |
6 | INSRR | 3.15697566 |
7 | WEE1 | 2.90717249 |
8 | NEK2 | 2.85923944 |
9 | FRK | 2.64446697 |
10 | MKNK2 | 2.37855062 |
11 | TSSK6 | 2.37437418 |
12 | BRSK2 | 2.32825091 |
13 | BRD4 | 2.26628987 |
14 | BUB1 | 2.25570055 |
15 | TTK | 2.19423936 |
16 | TRIM28 | 2.18451445 |
17 | ATR | 2.13916908 |
18 | PNCK | 2.10341005 |
19 | CHEK2 | 1.96731446 |
20 | PLK3 | 1.88131544 |
21 | ZAK | 1.86725719 |
22 | MKNK1 | 1.83260182 |
23 | PLK1 | 1.78431086 |
24 | CDK7 | 1.76859686 |
25 | TXK | 1.76377787 |
26 | PLK2 | 1.73214302 |
27 | ACVR1B | 1.70996952 |
28 | LATS1 | 1.66610042 |
29 | VRK1 | 1.60959351 |
30 | TAOK3 | 1.58281972 |
31 | CHEK1 | 1.51330075 |
32 | MAP3K14 | 1.50687653 |
33 | CDK4 | 1.40440031 |
34 | AURKB | 1.36939210 |
35 | YES1 | 1.36926125 |
36 | CDK8 | 1.34792382 |
37 | EIF2AK1 | 1.33698214 |
38 | TGFBR1 | 1.31028429 |
39 | BRSK1 | 1.30734449 |
40 | ATM | 1.29054109 |
41 | NEK1 | 1.28030178 |
42 | MAP4K2 | 1.26041086 |
43 | BCR | 1.25968317 |
44 | STK3 | 1.25394599 |
45 | IKBKE | 1.24381753 |
46 | IRAK1 | 1.22454875 |
47 | TLK1 | 1.22425914 |
48 | CDK9 | 1.21220492 |
49 | STK4 | 1.11565966 |
50 | EPHA3 | 1.10051768 |
51 | EPHA2 | 1.09255572 |
52 | PLK4 | 1.09105869 |
53 | MAPK13 | 1.08098727 |
54 | MST4 | 1.07673788 |
55 | PIM1 | 1.02777326 |
56 | CDK2 | 1.02320392 |
57 | MAP4K1 | 0.96680009 |
58 | IKBKB | 0.95538997 |
59 | CLK1 | 0.94939226 |
60 | IRAK2 | 0.94845796 |
61 | MELK | 0.94652865 |
62 | RPS6KB2 | 0.92323568 |
63 | MAP3K4 | 0.91185709 |
64 | CDK1 | 0.90328813 |
65 | BMPR2 | 0.88422456 |
66 | NUAK1 | 0.85200119 |
67 | DYRK3 | 0.82561796 |
68 | CDK19 | 0.81518480 |
69 | EIF2AK2 | 0.80923757 |
70 | STK10 | 0.80827310 |
71 | MTOR | 0.80454414 |
72 | JAK3 | 0.78491869 |
73 | SGK2 | 0.77180398 |
74 | TNIK | 0.77034792 |
75 | CSF1R | 0.76818250 |
76 | ALK | 0.76195083 |
77 | CSNK1D | 0.75579024 |
78 | STK38L | 0.74197433 |
79 | PIK3CG | 0.73299043 |
80 | FES | 0.71475106 |
81 | NLK | 0.69555026 |
82 | BMPR1B | 0.69049516 |
83 | EIF2AK3 | 0.68702538 |
84 | OXSR1 | 0.66771476 |
85 | CDK3 | 0.66648809 |
86 | LYN | 0.65743263 |
87 | DYRK1A | 0.65601815 |
88 | NEK6 | 0.64613503 |
89 | RPS6KA4 | 0.62969859 |
90 | CDK6 | 0.61627582 |
91 | JAK1 | 0.60721411 |
92 | DYRK1B | 0.60193621 |
93 | MARK3 | 0.59473198 |
94 | CCNB1 | 0.59266183 |
95 | CHUK | 0.58262277 |
96 | MAP3K8 | 0.58019925 |
97 | MAPK14 | 0.56724511 |
98 | ERBB3 | 0.56491063 |
99 | CAMK1D | 0.55640197 |
100 | PRKDC | 0.55479362 |
101 | AURKA | 0.55253742 |
102 | MAP2K7 | 0.54173202 |
103 | STK16 | 0.54105952 |
104 | EEF2K | 0.53857698 |
105 | MAPK15 | 0.53658798 |
106 | CSNK2A2 | 0.53557185 |
107 | RPS6KB1 | 0.53242134 |
108 | GSK3B | 0.52677155 |
109 | FLT3 | 0.52436992 |
110 | CSNK1A1L | 0.51261538 |
111 | PIK3CA | 0.51104236 |
112 | LCK | 0.50467064 |
113 | EPHA4 | 0.50013172 |
114 | SYK | 0.49628765 |
115 | CSNK1G2 | 0.49095533 |
116 | TEC | 0.48300945 |
117 | PINK1 | 0.45963164 |
118 | STK39 | 0.45750983 |
119 | SIK3 | 0.45533645 |
120 | JAK2 | 0.45114990 |
121 | MAP3K10 | 0.44733083 |
122 | PBK | 0.44422117 |
123 | CSK | 0.44183860 |
124 | FGFR1 | 0.43877100 |
125 | SIK2 | 0.43681999 |
126 | IRAK4 | 0.43670688 |
127 | KIT | 0.43297004 |
128 | BTK | 0.42323202 |
129 | DYRK2 | 0.42214455 |
130 | ERBB2 | 0.42111175 |
131 | TAOK2 | 0.41838546 |
132 | KSR2 | 0.41379086 |
133 | CSNK1E | 0.39546906 |
134 | MAPK10 | 0.39194430 |
135 | CSNK1G3 | 0.38178116 |
136 | PAK4 | 0.37651122 |
137 | LATS2 | 0.37396627 |
138 | AKT1 | 0.37236292 |
139 | MAPK1 | 0.36382382 |
140 | TYK2 | 0.36378889 |
141 | KSR1 | 0.36211633 |
142 | ITK | 0.36150876 |
143 | BLK | 0.35550374 |
144 | EGFR | 0.34542963 |
145 | RPS6KA5 | 0.33945404 |
146 | CSNK1G1 | 0.33631647 |
147 | FGR | 0.32220395 |
148 | AKT3 | 0.31785748 |
149 | TNK2 | 0.31200159 |
150 | CSNK2A1 | 0.30982336 |
151 | SCYL2 | 0.30713797 |
152 | CAMK4 | 0.30559936 |
153 | PRPF4B | 0.29477613 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Mismatch repair_Homo sapiens_hsa03430 | 4.39015769 |
2 | DNA replication_Homo sapiens_hsa03030 | 4.13204636 |
3 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 3.79669593 |
4 | RNA transport_Homo sapiens_hsa03013 | 3.22707996 |
5 | Spliceosome_Homo sapiens_hsa03040 | 3.13239513 |
6 | Cell cycle_Homo sapiens_hsa04110 | 2.92381409 |
7 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 2.75964528 |
8 | Homologous recombination_Homo sapiens_hsa03440 | 2.74331770 |
9 | RNA polymerase_Homo sapiens_hsa03020 | 2.66472153 |
10 | Non-homologous end-joining_Homo sapiens_hsa03450 | 2.59577949 |
11 | Base excision repair_Homo sapiens_hsa03410 | 2.56776805 |
12 | Nucleotide excision repair_Homo sapiens_hsa03420 | 2.49760862 |
13 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 2.49637891 |
14 | Protein export_Homo sapiens_hsa03060 | 2.47696824 |
15 | Asthma_Homo sapiens_hsa05310 | 2.45268953 |
16 | One carbon pool by folate_Homo sapiens_hsa00670 | 2.29592162 |
17 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 2.29344208 |
18 | RNA degradation_Homo sapiens_hsa03018 | 2.25565039 |
19 | Basal transcription factors_Homo sapiens_hsa03022 | 2.14661613 |
20 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.89437463 |
21 | p53 signaling pathway_Homo sapiens_hsa04115 | 1.69136757 |
22 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 1.55106455 |
23 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 1.55025077 |
24 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.48301592 |
25 | Leishmaniasis_Homo sapiens_hsa05140 | 1.47811389 |
26 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.45842159 |
27 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.37711883 |
28 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.31387969 |
29 | Viral carcinogenesis_Homo sapiens_hsa05203 | 1.25876334 |
30 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 1.22697712 |
31 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 1.17842656 |
32 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.14097694 |
33 | Toxoplasmosis_Homo sapiens_hsa05145 | 1.13401032 |
34 | Regulation of autophagy_Homo sapiens_hsa04140 | 1.13027049 |
35 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.12971170 |
36 | Notch signaling pathway_Homo sapiens_hsa04330 | 1.12186296 |
37 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.11925196 |
38 | Purine metabolism_Homo sapiens_hsa00230 | 1.08499529 |
39 | HTLV-I infection_Homo sapiens_hsa05166 | 1.05496451 |
40 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.02803993 |
41 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 1.01681353 |
42 | Basal cell carcinoma_Homo sapiens_hsa05217 | 1.00198057 |
43 | Colorectal cancer_Homo sapiens_hsa05210 | 0.97570790 |
44 | Lysine degradation_Homo sapiens_hsa00310 | 0.95968474 |
45 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.95500671 |
46 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.95022723 |
47 | Measles_Homo sapiens_hsa05162 | 0.94054453 |
48 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.93916581 |
49 | Proteasome_Homo sapiens_hsa03050 | 0.93906987 |
50 | Osteoclast differentiation_Homo sapiens_hsa04380 | 0.91764168 |
51 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.91110831 |
52 | Tuberculosis_Homo sapiens_hsa05152 | 0.88791593 |
53 | Olfactory transduction_Homo sapiens_hsa04740 | 0.83802365 |
54 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.83441328 |
55 | Alcoholism_Homo sapiens_hsa05034 | 0.82705909 |
56 | Ribosome_Homo sapiens_hsa03010 | 0.79447710 |
57 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.76943825 |
58 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.76533216 |
59 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.69634804 |
60 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.69106184 |
61 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.68866381 |
62 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.68805905 |
63 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.68712297 |
64 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 0.68162999 |
65 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.66373585 |
66 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.65476004 |
67 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.65462738 |
68 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.64969507 |
69 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.63736300 |
70 | Influenza A_Homo sapiens_hsa05164 | 0.62097306 |
71 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.61991406 |
72 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.61143217 |
73 | Hepatitis B_Homo sapiens_hsa05161 | 0.60763849 |
74 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.60314787 |
75 | Nicotine addiction_Homo sapiens_hsa05033 | 0.59862617 |
76 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.59324689 |
77 | Taste transduction_Homo sapiens_hsa04742 | 0.58852330 |
78 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.57816648 |
79 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.55675723 |
80 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.54575360 |
81 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 0.54239955 |
82 | Thyroid cancer_Homo sapiens_hsa05216 | 0.54085829 |
83 | Prostate cancer_Homo sapiens_hsa05215 | 0.53685468 |
84 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.53321563 |
85 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.52549425 |
86 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.51520817 |
87 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.50718784 |
88 | Pathways in cancer_Homo sapiens_hsa05200 | 0.50514060 |
89 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.50481984 |
90 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.50307406 |
91 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.49133672 |
92 | Endometrial cancer_Homo sapiens_hsa05213 | 0.48811079 |
93 | Legionellosis_Homo sapiens_hsa05134 | 0.48405281 |
94 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.48290695 |
95 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.48072346 |
96 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.47732804 |
97 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.46461432 |
98 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.45401917 |
99 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.44092192 |
100 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.43936968 |
101 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.41796848 |
102 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.40998392 |
103 | Adherens junction_Homo sapiens_hsa04520 | 0.40740491 |
104 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.40061214 |
105 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.39990742 |
106 | Apoptosis_Homo sapiens_hsa04210 | 0.38971109 |
107 | Circadian rhythm_Homo sapiens_hsa04710 | 0.38591269 |
108 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.37859027 |
109 | Phototransduction_Homo sapiens_hsa04744 | 0.37728929 |
110 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.36871749 |
111 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.34931971 |
112 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.32813618 |
113 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.32206535 |
114 | Long-term depression_Homo sapiens_hsa04730 | 0.32108393 |
115 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 0.32070914 |
116 | Allograft rejection_Homo sapiens_hsa05330 | 0.31816261 |
117 | Viral myocarditis_Homo sapiens_hsa05416 | 0.31691461 |
118 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.31418669 |
119 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.31334031 |
120 | Renin secretion_Homo sapiens_hsa04924 | 0.31195284 |
121 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.31134262 |
122 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.30021217 |
123 | Melanoma_Homo sapiens_hsa05218 | 0.28589535 |
124 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.28575090 |
125 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.28382678 |
126 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.28228117 |
127 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.27633112 |
128 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.27091395 |
129 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.26294023 |
130 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 0.25623728 |
131 | Platelet activation_Homo sapiens_hsa04611 | 0.25543835 |
132 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.24153201 |
133 | PI3K-Akt signaling pathway_Homo sapiens_hsa04151 | 0.23268645 |
134 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.19824939 |
135 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.18335512 |
136 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.17449571 |
137 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.16893184 |
138 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.16293065 |
139 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.16258465 |
140 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.15972828 |