UTP15

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1attachment of spindle microtubules to kinetochore (GO:0008608)4.84180119
2DNA replication initiation (GO:0006270)4.81950987
3DNA unwinding involved in DNA replication (GO:0006268)4.79559845
4nuclear pore organization (GO:0006999)4.66219675
5protein localization to kinetochore (GO:0034501)4.63807295
6DNA strand elongation involved in DNA replication (GO:0006271)4.57722993
7mitotic metaphase plate congression (GO:0007080)4.54852779
8DNA double-strand break processing (GO:0000729)4.48784932
9nuclear pore complex assembly (GO:0051292)4.45861914
10mitotic nuclear envelope disassembly (GO:0007077)4.42940499
11DNA strand elongation (GO:0022616)4.40531518
12nucleobase biosynthetic process (GO:0046112)4.38650843
13mitotic sister chromatid segregation (GO:0000070)4.26633849
14telomere maintenance via semi-conservative replication (GO:0032201)4.25992524
15formation of translation preinitiation complex (GO:0001731)4.23967355
16purine nucleobase biosynthetic process (GO:0009113)4.22920102
17DNA replication checkpoint (GO:0000076)4.16573896
18DNA replication-dependent nucleosome assembly (GO:0006335)4.14300382
19DNA replication-dependent nucleosome organization (GO:0034723)4.14300382
20IMP biosynthetic process (GO:0006188)4.11226106
21membrane disassembly (GO:0030397)4.10354593
22nuclear envelope disassembly (GO:0051081)4.10354593
23ribosome assembly (GO:0042255)4.04630621
24sister chromatid segregation (GO:0000819)4.03233067
25folic acid-containing compound biosynthetic process (GO:0009396)4.00930412
26proteasome assembly (GO:0043248)4.00128424
27CENP-A containing nucleosome assembly (GO:0034080)3.98416450
28chromatin remodeling at centromere (GO:0031055)3.98350242
29ribosome biogenesis (GO:0042254)3.94016851
30telomere maintenance via recombination (GO:0000722)3.91538785
31metaphase plate congression (GO:0051310)3.90756962
32protein localization to chromosome, centromeric region (GO:0071459)3.88522843
33mitotic recombination (GO:0006312)3.80602341
34DNA replication-independent nucleosome organization (GO:0034724)3.79252426
35DNA replication-independent nucleosome assembly (GO:0006336)3.79252426
36viral mRNA export from host cell nucleus (GO:0046784)3.78562559
37regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.70082387
38IMP metabolic process (GO:0046040)3.69824503
39maturation of SSU-rRNA (GO:0030490)3.65419318
40pore complex assembly (GO:0046931)3.64250477
41negative regulation of DNA-dependent DNA replication (GO:2000104)3.59431220
42mitotic chromosome condensation (GO:0007076)3.57703930
43regulation of spindle organization (GO:0090224)3.57295495
44mitotic sister chromatid cohesion (GO:0007064)3.55675602
45telomere maintenance via telomere lengthening (GO:0010833)3.55330817
46establishment of chromosome localization (GO:0051303)3.54389751
47kinetochore organization (GO:0051383)3.52659146
48double-strand break repair via nonhomologous end joining (GO:0006303)3.51145966
49non-recombinational repair (GO:0000726)3.51145966
50mitochondrial RNA metabolic process (GO:0000959)3.48650622
51somatic hypermutation of immunoglobulin genes (GO:0016446)3.48524666
52somatic diversification of immune receptors via somatic mutation (GO:0002566)3.48524666
53mitotic spindle checkpoint (GO:0071174)3.47993615
54rRNA methylation (GO:0031167)3.45633675
55negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.43894604
56regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.41744661
57positive regulation of chromosome segregation (GO:0051984)3.40398558
58DNA duplex unwinding (GO:0032508)3.38212700
59establishment of integrated proviral latency (GO:0075713)3.37850185
60histone exchange (GO:0043486)3.37658558
61replication fork processing (GO:0031297)3.37412128
62somatic recombination of immunoglobulin genes involved in immune response (GO:0002204)3.36267809
63somatic diversification of immunoglobulins involved in immune response (GO:0002208)3.36267809
64isotype switching (GO:0045190)3.36267809
65DNA geometric change (GO:0032392)3.36012276
66nucleotide-excision repair, DNA gap filling (GO:0006297)3.34981625
67histone mRNA metabolic process (GO:0008334)3.32797013
68regulation of mitotic spindle checkpoint (GO:1903504)3.32278561
69regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)3.32278561
70DNA catabolic process, exonucleolytic (GO:0000738)3.30004262
71rRNA modification (GO:0000154)3.29751333
72ribonucleoprotein complex biogenesis (GO:0022613)3.28879552
73anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.28797719
74regulation of centrosome cycle (GO:0046605)3.26740733
75maturation of 5.8S rRNA (GO:0000460)3.25823102
76positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.25649725
77regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.24711513
78establishment of protein localization to mitochondrial membrane (GO:0090151)3.24448189
79kinetochore assembly (GO:0051382)3.24386109
80spliceosomal snRNP assembly (GO:0000387)3.22970259
81* rRNA processing (GO:0006364)3.22029985
82transcription elongation from RNA polymerase III promoter (GO:0006385)3.21609504
83termination of RNA polymerase III transcription (GO:0006386)3.21609504
84regulation of centriole replication (GO:0046599)3.20392677
85nuclear envelope organization (GO:0006998)3.17351701
86histone H2A acetylation (GO:0043968)3.16682020
87RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503)3.16064454
88negative regulation of chromosome segregation (GO:0051985)3.15004911
89regulation of DNA endoreduplication (GO:0032875)3.14920297
90chromatin assembly or disassembly (GO:0006333)3.14490083
91regulation of helicase activity (GO:0051095)3.13807494
92ribosomal small subunit assembly (GO:0000028)3.12740212
93spindle checkpoint (GO:0031577)3.12638183
94* rRNA metabolic process (GO:0016072)3.12186671
95negative regulation of ligase activity (GO:0051352)3.11949862
96negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.11949862
97regulation of nuclear cell cycle DNA replication (GO:0033262)3.11611732
98regulation of mitotic metaphase/anaphase transition (GO:0030071)3.10284332
99ribosomal large subunit biogenesis (GO:0042273)3.09400043
100regulation of chromosome segregation (GO:0051983)3.09331855
101negative regulation of mitotic sister chromatid separation (GO:2000816)3.08610026
102negative regulation of mitotic sister chromatid segregation (GO:0033048)3.08610026
103negative regulation of mitotic metaphase/anaphase transition (GO:0045841)3.08610026
104negative regulation of sister chromatid segregation (GO:0033046)3.08610026
105pseudouridine synthesis (GO:0001522)3.07696924
106synapsis (GO:0007129)3.06403838
107exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.04751616
108amino acid activation (GO:0043038)3.04367378
109tRNA aminoacylation (GO:0043039)3.04367378
110DNA deamination (GO:0045006)3.04276981
111protein localization to chromosome (GO:0034502)3.03720484
112regulation of metaphase/anaphase transition of cell cycle (GO:1902099)3.03627361
113spindle assembly checkpoint (GO:0071173)3.03395889
114regulation of double-strand break repair via homologous recombination (GO:0010569)3.02036314
115response to X-ray (GO:0010165)3.01858548
116somatic recombination of immunoglobulin gene segments (GO:0016447)3.01814983
117tRNA aminoacylation for protein translation (GO:0006418)3.00296509
118negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)3.00044367
119regulation of mitotic spindle organization (GO:0060236)2.99722115
120dosage compensation (GO:0007549)2.99238488
121DNA damage response, detection of DNA damage (GO:0042769)2.98809777
122positive regulation of mitotic metaphase/anaphase transition (GO:0045842)2.98225350
123positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)2.98225350
124positive regulation of mitotic sister chromatid separation (GO:1901970)2.98225350
125chromosome segregation (GO:0007059)2.97247665
126maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)2.96658421
127resolution of meiotic recombination intermediates (GO:0000712)2.96602837
128meiotic chromosome segregation (GO:0045132)2.96220739
129mitotic spindle assembly checkpoint (GO:0007094)2.95088033
130RNA splicing, via transesterification reactions (GO:0000375)2.94312040
131respiratory chain complex IV assembly (GO:0008535)2.94148870
132transcription from mitochondrial promoter (GO:0006390)2.93920337
133nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)2.93742261
134mismatch repair (GO:0006298)2.93022156
135protein K6-linked ubiquitination (GO:0085020)2.92854755
136negative regulation of mRNA splicing, via spliceosome (GO:0048025)2.92130350
137RNA splicing, via transesterification reactions with bulged adenosine as nucleophile (GO:0000377)2.92103704
138mRNA splicing, via spliceosome (GO:0000398)2.92103704
139termination of RNA polymerase II transcription (GO:0006369)2.91980472
140regulation of mitotic sister chromatid separation (GO:0010965)2.91608860
141regulation of mitotic sister chromatid segregation (GO:0033047)2.91608860
142regulation of sister chromatid segregation (GO:0033045)2.91608860
143postreplication repair (GO:0006301)2.90768031

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human9.98682269
2FOXM1_23109430_ChIP-Seq_U2OS_Human4.53867388
3MYC_18555785_ChIP-Seq_MESCs_Mouse4.33746188
4E2F4_17652178_ChIP-ChIP_JURKAT_Human4.07833588
5EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.33812965
6FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human3.28392937
7MYC_19079543_ChIP-ChIP_MESCs_Mouse3.04459569
8KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.98709842
9MYC_19030024_ChIP-ChIP_MESCs_Mouse2.89876832
10EST1_17652178_ChIP-ChIP_JURKAT_Human2.72820867
11* MYC_18358816_ChIP-ChIP_MESCs_Mouse2.68970997
12ETS1_20019798_ChIP-Seq_JURKAT_Human2.52544493
13* JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.46106092
14EGR1_19374776_ChIP-ChIP_THP-1_Human2.44338155
15AR_21909140_ChIP-Seq_LNCAP_Human2.41263411
16GABP_17652178_ChIP-ChIP_JURKAT_Human2.41124690
17NELFA_20434984_ChIP-Seq_ESCs_Mouse2.40218096
18* KDM5B_21448134_ChIP-Seq_MESCs_Mouse2.39130127
19E2F1_21310950_ChIP-Seq_MCF-7_Human2.35348658
20CREB1_15753290_ChIP-ChIP_HEK293T_Human2.33078551
21HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.26925110
22XRN2_22483619_ChIP-Seq_HELA_Human2.24499271
23VDR_23849224_ChIP-Seq_CD4+_Human2.15479463
24ZNF274_21170338_ChIP-Seq_K562_Hela2.11057158
25CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.05004867
26MYBL2_22936984_ChIP-ChIP_MESCs_Mouse2.03836703
27EWS_26573619_Chip-Seq_HEK293_Human2.01056624
28MYCN_18555785_ChIP-Seq_MESCs_Mouse1.99223347
29FLI1_27457419_Chip-Seq_LIVER_Mouse1.95275525
30DCP1A_22483619_ChIP-Seq_HELA_Human1.94237827
31MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.92399267
32POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.88299077
33FOXP3_21729870_ChIP-Seq_TREG_Human1.85530434
34MYC_22102868_ChIP-Seq_BL_Human1.83753321
35* E2F1_18555785_ChIP-Seq_MESCs_Mouse1.83681989
36FUS_26573619_Chip-Seq_HEK293_Human1.77939553
37PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.77578707
38* THAP11_20581084_ChIP-Seq_MESCs_Mouse1.74954171
39YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.74915432
40GABP_19822575_ChIP-Seq_HepG2_Human1.74732059
41ELF1_17652178_ChIP-ChIP_JURKAT_Human1.74610297
42NANOG_18555785_ChIP-Seq_MESCs_Mouse1.74387683
43TTF2_22483619_ChIP-Seq_HELA_Human1.69441562
44* ELK1_19687146_ChIP-ChIP_HELA_Human1.63713653
45NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.60872955
46VDR_22108803_ChIP-Seq_LS180_Human1.60682157
47CIITA_25753668_ChIP-Seq_RAJI_Human1.59669686
48SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.58638672
49* POU3F2_20337985_ChIP-ChIP_501MEL_Human1.57661065
50NOTCH1_21737748_ChIP-Seq_TLL_Human1.57528371
51POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.54773942
52* HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.54595084
53FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.53345094
54ZFX_18555785_ChIP-Seq_MESCs_Mouse1.52324682
55MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.49743432
56KDM5A_27292631_Chip-Seq_BREAST_Human1.48535399
57CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.41192729
58ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.41129356
59HOXB4_20404135_ChIP-ChIP_EML_Mouse1.39440647
60POU5F1_16153702_ChIP-ChIP_HESCs_Human1.37108701
61FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.35282175
62PCGF2_27294783_Chip-Seq_ESCs_Mouse1.34591707
63TP63_19390658_ChIP-ChIP_HaCaT_Human1.34370652
64TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.33490286
65SOX2_18555785_ChIP-Seq_MESCs_Mouse1.32361931
66SALL1_21062744_ChIP-ChIP_HESCs_Human1.31303511
67SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.31085250
68ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.29683433
69SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.29132198
70POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.28610721
71HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.27997450
72RBPJ_22232070_ChIP-Seq_NCS_Mouse1.27071841
73* KLF4_18555785_ChIP-Seq_MESCs_Mouse1.26844766
74E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.24915867
75PADI4_21655091_ChIP-ChIP_MCF-7_Human1.24107566
76YY1_21170310_ChIP-Seq_MESCs_Mouse1.20867110
77STAT3_1855785_ChIP-Seq_MESCs_Mouse1.18866560
78NANOG_16153702_ChIP-ChIP_HESCs_Human1.16962243
79P300_19829295_ChIP-Seq_ESCs_Human1.16801197
80E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.16552411
81CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.16514550
82CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.15507136
83CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.14094771
84TFEB_21752829_ChIP-Seq_HELA_Human1.11485989
85ELK1_22589737_ChIP-Seq_MCF10A_Human1.09762561
86DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.09387686
87* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.09015774
88TAF15_26573619_Chip-Seq_HEK293_Human1.08946924
89ERG_20887958_ChIP-Seq_HPC-7_Mouse1.08654301
90ZFP57_27257070_Chip-Seq_ESCs_Mouse1.05238713
91MYC_18940864_ChIP-ChIP_HL60_Human1.05202476
92KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.02407504
93SOX2_16153702_ChIP-ChIP_HESCs_Human1.01958154
94FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.00151682
95IGF1R_20145208_ChIP-Seq_DFB_Human1.00050480
96* CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.99863621
97PDX1_19855005_ChIP-ChIP_MIN6_Mouse0.99034969
98EZH2_27294783_Chip-Seq_NPCs_Mouse0.98987021
99CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.98705401
100GLI1_17442700_ChIP-ChIP_MESCs_Mouse0.96448427
101SRF_21415370_ChIP-Seq_HL-1_Mouse0.96259973
102HNF4A_19761587_ChIP-ChIP_CACO-2_Human0.95053088
103ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.94907118
104TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.92327339
105NANOG_21062744_ChIP-ChIP_HESCs_Human0.92286964
106KLF2_18264089_ChIP-ChIP_MESCs_Mouse0.92187414
107KLF5_18264089_ChIP-ChIP_MESCs_Mouse0.92187414
108KLF4_18264089_ChIP-ChIP_MESCs_Mouse0.92187414
109RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse0.91839101
110PCGF2_27294783_Chip-Seq_NPCs_Mouse0.90282235
111KLF4_18358816_ChIP-ChIP_MESCs_Mouse0.90022811
112SUZ12_27294783_Chip-Seq_NPCs_Mouse0.89966131
113SPI1_22096565_ChIP-ChIP_GC-B_Mouse0.89776737
114ZFP281_18358816_ChIP-ChIP_MESCs_Mouse0.88078039
115NANOG_18700969_ChIP-ChIP_MESCs_Mouse0.87174031
116SOX17_20123909_ChIP-Seq_XEN_Mouse0.86957439
117IRF1_19129219_ChIP-ChIP_H3396_Human0.86832638
118NFE2_27457419_Chip-Seq_LIVER_Mouse0.86776920
119ER_23166858_ChIP-Seq_MCF-7_Human0.85857992
120CEBPB_23403033_ChIP-Seq_LIVER_Mouse0.85792279
121VDR_21846776_ChIP-Seq_THP-1_Human0.84819215
122NACC1_18358816_ChIP-ChIP_MESCs_Mouse0.84299546
123TP53_22573176_ChIP-Seq_HFKS_Human0.84077227
124SMAD4_19686287_ChIP-ChIP_HaCaT_Human0.83961620
125SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.83526843
126GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.83441670
127SPI1_23547873_ChIP-Seq_NB4_Human0.82743657
128NANOG_18358816_ChIP-ChIP_MESCs_Mouse0.80940145
129BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.80334266
130TCF3_18692474_ChIP-Seq_MEFs_Mouse0.79958072
131DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.78903367
132NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse0.78884226
133PRDM5_23873026_ChIP-Seq_MEFs_Mouse0.78771879
134MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.78754127
135AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.78435104
136GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.77646150
137EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.74296175
138CRX_20693478_ChIP-Seq_RETINA_Mouse0.73760655

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching5.21042412
2MP0010094_abnormal_chromosome_stability4.86357214
3MP0003111_abnormal_nucleus_morphology4.50732714
4MP0004957_abnormal_blastocyst_morpholog4.25943488
5MP0008057_abnormal_DNA_replication4.07067462
6MP0003077_abnormal_cell_cycle4.03808927
7MP0008058_abnormal_DNA_repair3.52807486
8MP0008007_abnormal_cellular_replicative2.98920058
9MP0003123_paternal_imprinting2.77714091
10MP0008932_abnormal_embryonic_tissue2.73545419
11MP0010307_abnormal_tumor_latency2.60277004
12MP0000350_abnormal_cell_proliferation2.45465571
13MP0001730_embryonic_growth_arrest2.36437679
14MP0002396_abnormal_hematopoietic_system2.36342717
15MP0009697_abnormal_copulation2.29549919
16MP0008877_abnormal_DNA_methylation2.25950375
17MP0010352_gastrointestinal_tract_polyps2.16993088
18MP0003890_abnormal_embryonic-extraembry1.97668949
19MP0003786_premature_aging1.95332754
20MP0001672_abnormal_embryogenesis/_devel1.92225141
21MP0005380_embryogenesis_phenotype1.92225141
22MP0000372_irregular_coat_pigmentation1.83892357
23MP0001697_abnormal_embryo_size1.83219808
24MP0002938_white_spotting1.82959443
25MP0006072_abnormal_retinal_apoptosis1.79315878
26MP0000490_abnormal_crypts_of1.73014529
27MP0003984_embryonic_growth_retardation1.72815421
28MP0002085_abnormal_embryonic_tissue1.72636608
29MP0002088_abnormal_embryonic_growth/wei1.68754224
30MP0005076_abnormal_cell_differentiation1.66301383
31MP0002084_abnormal_developmental_patter1.65602984
32MP0006035_abnormal_mitochondrial_morpho1.64576503
33MP0002080_prenatal_lethality1.62565714
34MP0003718_maternal_effect1.60408273
35MP0004808_abnormal_hematopoietic_stem1.57308934
36MP0004197_abnormal_fetal_growth/weight/1.56669255
37MP0002086_abnormal_extraembryonic_tissu1.54593234
38MP0003121_genomic_imprinting1.50833057
39MP0003646_muscle_fatigue1.43222791
40MP0009333_abnormal_splenocyte_physiolog1.42230245
41MP0000313_abnormal_cell_death1.40098995
42MP0002019_abnormal_tumor_incidence1.38579907
43MP0005075_abnormal_melanosome_morpholog1.31852519
44MP0001293_anophthalmia1.30384849
45MP0006292_abnormal_olfactory_placode1.28863105
46MP0003763_abnormal_thymus_physiology1.25052921
47MP0006036_abnormal_mitochondrial_physio1.22928743
48MP0000569_abnormal_digit_pigmentation1.22332683
49MP0001529_abnormal_vocalization1.21897552
50MP0002254_reproductive_system_inflammat1.21268239
51MP0005253_abnormal_eye_physiology1.20993474
52MP0002234_abnormal_pharynx_morphology1.20917654
53MP0000703_abnormal_thymus_morphology1.20388918
54MP0003567_abnormal_fetal_cardiomyocyte1.20290415
55MP0010030_abnormal_orbit_morphology1.17381867
56MP0009053_abnormal_anal_canal1.17333250
57MP0003787_abnormal_imprinting1.17082064
58MP0005408_hypopigmentation1.16507806
59MP0004133_heterotaxia1.15436108
60MP0002837_dystrophic_cardiac_calcinosis1.12298044
61MP0003806_abnormal_nucleotide_metabolis1.11867789
62MP0002398_abnormal_bone_marrow1.11554999
63MP0005397_hematopoietic_system_phenotyp1.09084473
64MP0001545_abnormal_hematopoietic_system1.09084473
65MP0003186_abnormal_redox_activity1.08951491
66MP0003315_abnormal_perineum_morphology1.08221443
67MP0002210_abnormal_sex_determination1.06551389
68MP0000647_abnormal_sebaceous_gland1.04130320
69MP0002111_abnormal_tail_morphology1.03834532
70MP0002722_abnormal_immune_system1.00954512
71MP0005395_other_phenotype1.00657457
72MP0000689_abnormal_spleen_morphology0.98056708
73MP0000427_abnormal_hair_cycle0.96475316
74MP0001145_abnormal_male_reproductive0.94475201
75MP0002877_abnormal_melanocyte_morpholog0.93118980
76MP0003941_abnormal_skin_development0.91753018
77MP0005391_vision/eye_phenotype0.90955257
78MP0005379_endocrine/exocrine_gland_phen0.90704587
79MP0009672_abnormal_birth_weight0.89980085
80MP0003119_abnormal_digestive_system0.88038252
81MP0000383_abnormal_hair_follicle0.87793088
82MP0002163_abnormal_gland_morphology0.87732779
83MP0005389_reproductive_system_phenotype0.87572352
84MP0005621_abnormal_cell_physiology0.87350337
85MP0000858_altered_metastatic_potential0.87186753
86MP0004215_abnormal_myocardial_fiber0.86767367
87MP0001119_abnormal_female_reproductive0.85805372
88MP0005384_cellular_phenotype0.85150488
89MP0001919_abnormal_reproductive_system0.84247554
90MP0002009_preneoplasia0.84241853
91MP0000428_abnormal_craniofacial_morphol0.82519339
92MP0000653_abnormal_sex_gland0.82018714
93MP0002160_abnormal_reproductive_system0.81602427
94MP0003937_abnormal_limbs/digits/tail_de0.81044054
95MP0005551_abnormal_eye_electrophysiolog0.79811579
96MP0002429_abnormal_blood_cell0.79502512
97MP0001929_abnormal_gametogenesis0.79221100
98MP0000516_abnormal_urinary_system0.77965472
99MP0005367_renal/urinary_system_phenotyp0.77965472
100MP0009703_decreased_birth_body0.77776467
101MP0000631_abnormal_neuroendocrine_gland0.76892773
102MP0000371_diluted_coat_color0.75688701
103MP0003195_calcinosis0.75585456
104MP0009278_abnormal_bone_marrow0.75400805
105MP0002751_abnormal_autonomic_nervous0.73920498
106MP0010678_abnormal_skin_adnexa0.73889306
107MP0004147_increased_porphyrin_level0.73747885
108MP0002102_abnormal_ear_morphology0.73369203
109MP0003950_abnormal_plasma_membrane0.72693344
110MP0000537_abnormal_urethra_morphology0.71708230
111MP0002697_abnormal_eye_size0.71255129
112MP0002075_abnormal_coat/hair_pigmentati0.71147353
113MP0001661_extended_life_span0.71113334
114MP0000579_abnormal_nail_morphology0.70796262
115MP0002282_abnormal_trachea_morphology0.70578134
116MP0004142_abnormal_muscle_tone0.70508602
117MP0001915_intracranial_hemorrhage0.69107154
118MP0000716_abnormal_immune_system0.68943470
119MP0001286_abnormal_eye_development0.68708956
120MP0003755_abnormal_palate_morphology0.68165964
121MP0003011_delayed_dark_adaptation0.67543324
122MP0002092_abnormal_eye_morphology0.67109867
123MP0002095_abnormal_skin_pigmentation0.66991089
124MP0002177_abnormal_outer_ear0.66758339
125MP0003136_yellow_coat_color0.66754979
126MP0002233_abnormal_nose_morphology0.66206865
127MP0000477_abnormal_intestine_morphology0.65572295
128MP0003698_abnormal_male_reproductive0.65550581
129MP0000432_abnormal_head_morphology0.64837572
130MP0005084_abnormal_gallbladder_morpholo0.64209519
131MP0003221_abnormal_cardiomyocyte_apopto0.64173453
132MP0003943_abnormal_hepatobiliary_system0.63633618
133MP0005023_abnormal_wound_healing0.63097477
134MP0003283_abnormal_digestive_organ0.62785252
135MP0002090_abnormal_vision0.60908573
136MP0001764_abnormal_homeostasis0.60902044
137MP0003115_abnormal_respiratory_system0.60568462
138MP0003861_abnormal_nervous_system0.60401494
139MP0000358_abnormal_cell_content/0.59993838
140MP0000733_abnormal_muscle_development0.59635184
141MP0000566_synostosis0.57911348
142MP0001186_pigmentation_phenotype0.56473017
143MP0001800_abnormal_humoral_immune0.56433812
144MP0002653_abnormal_ependyma_morphology0.56124560
145MP0004264_abnormal_extraembryonic_tissu0.54697417
146MP0003936_abnormal_reproductive_system0.52380764
147MP0005671_abnormal_response_to0.52242047
148MP0002420_abnormal_adaptive_immunity0.51935049
149MP0003448_altered_tumor_morphology0.51349164

Predicted human phenotypes

RankGene SetZ-score
1Birth length less than 3rd percentile (HP:0003561)4.77064329
2Chromsome breakage (HP:0040012)3.63958752
3Chromosomal breakage induced by crosslinking agents (HP:0003221)3.54017627
4Ependymoma (HP:0002888)3.51865347
5Abnormality of the anterior horn cell (HP:0006802)3.43007740
6Degeneration of anterior horn cells (HP:0002398)3.43007740
7Breast hypoplasia (HP:0003187)3.39305863
8Impulsivity (HP:0100710)3.37951651
9Abnormality of the labia minora (HP:0012880)3.37447924
10Increased hepatocellular lipid droplets (HP:0006565)3.36923078
11Carpal bone hypoplasia (HP:0001498)3.34457036
12Medulloblastoma (HP:0002885)3.32023413
13Patellar aplasia (HP:0006443)3.26156420
14Aplasia/Hypoplasia of the patella (HP:0006498)3.07141961
15Abnormality of chromosome stability (HP:0003220)3.07064029
16Agnosia (HP:0010524)3.05853045
17Acute necrotizing encephalopathy (HP:0006965)3.04652934
18Lipid accumulation in hepatocytes (HP:0006561)3.03167730
19Meckel diverticulum (HP:0002245)3.01628658
20Selective tooth agenesis (HP:0001592)3.00960350
21Aplasia/Hypoplasia of the uvula (HP:0010293)2.99397621
22Oral leukoplakia (HP:0002745)2.97303676
23Acute encephalopathy (HP:0006846)2.94187137
24Colon cancer (HP:0003003)2.93315026
25Abnormality of the ileum (HP:0001549)2.91354001
26Methylmalonic acidemia (HP:0002912)2.87054211
27Abnormality of the preputium (HP:0100587)2.87026555
28Abnormality of the pons (HP:0007361)2.86979656
29Absent radius (HP:0003974)2.82989628
30Premature graying of hair (HP:0002216)2.77205336
31Hypoplasia of the pons (HP:0012110)2.74515686
32Reticulocytopenia (HP:0001896)2.74505273
33Type I transferrin isoform profile (HP:0003642)2.72771181
34Absent thumb (HP:0009777)2.72333928
35Increased CSF lactate (HP:0002490)2.71095373
36Rough bone trabeculation (HP:0100670)2.67451207
37Myelodysplasia (HP:0002863)2.67076367
38Progressive macrocephaly (HP:0004481)2.64863299
39Abnormal number of incisors (HP:0011064)2.64367274
40Aplasia involving forearm bones (HP:0009822)2.61299459
41Absent forearm bone (HP:0003953)2.61299459
42Reduced antithrombin III activity (HP:0001976)2.56806294
43Abnormal mitochondria in muscle tissue (HP:0008316)2.56802666
44Abnormality of methionine metabolism (HP:0010901)2.52814017
45Small intestinal stenosis (HP:0012848)2.52470890
46Duodenal stenosis (HP:0100867)2.52470890
47Neoplasm of the pancreas (HP:0002894)2.51535546
48Aplasia/Hypoplasia involving the carpal bones (HP:0006502)2.51053456
49Basal cell carcinoma (HP:0002671)2.50993112
50Bone marrow hypocellularity (HP:0005528)2.50047496
51Mitochondrial inheritance (HP:0001427)2.49213862
52Pelvic girdle muscle weakness (HP:0003749)2.45577411
53Facial hemangioma (HP:0000329)2.45467063
54Glioma (HP:0009733)2.41609070
55Aplastic anemia (HP:0001915)2.41309819
56Ectopic kidney (HP:0000086)2.41047556
57Rhabdomyosarcoma (HP:0002859)2.40917616
58Abnormal number of erythroid precursors (HP:0012131)2.37444540
59Abnormality of cells of the erythroid lineage (HP:0012130)2.37078540
60Abnormality of the renal cortex (HP:0011035)2.36401509
61Astrocytoma (HP:0009592)2.35268687
62Abnormality of the astrocytes (HP:0100707)2.35268687
63Clubbing of toes (HP:0100760)2.33235320
64Pancreatic cysts (HP:0001737)2.32429942
65Abnormal protein glycosylation (HP:0012346)2.30955399
66Abnormal glycosylation (HP:0012345)2.30955399
67Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.30955399
68Abnormal protein N-linked glycosylation (HP:0012347)2.30955399
69Spinal muscular atrophy (HP:0007269)2.30627771
7011 pairs of ribs (HP:0000878)2.29512590
71Cerebral hypomyelination (HP:0006808)2.29070930
72Cerebral edema (HP:0002181)2.28566079
73Amaurosis fugax (HP:0100576)2.28370043
74Overlapping toe (HP:0001845)2.25293789
75Sloping forehead (HP:0000340)2.25160765
76Cellular immunodeficiency (HP:0005374)2.24969942
77Molar tooth sign on MRI (HP:0002419)2.24872489
78Abnormality of midbrain morphology (HP:0002418)2.24872489
79Renal cortical cysts (HP:0000803)2.23378935
80Abnormality of alanine metabolism (HP:0010916)2.23298659
81Hyperalaninemia (HP:0003348)2.23298659
82Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.23298659
83Methylmalonic aciduria (HP:0012120)2.22465213
84Increased serum lactate (HP:0002151)2.19121432
85Supernumerary spleens (HP:0009799)2.18266386
86Duplicated collecting system (HP:0000081)2.17765330
87Pancreatic fibrosis (HP:0100732)2.16504457
88Abnormality of the duodenum (HP:0002246)2.15916522
89Tracheoesophageal fistula (HP:0002575)2.15442921
90Deviation of the thumb (HP:0009603)2.14146022
91Atresia of the external auditory canal (HP:0000413)2.13039262
92Renal Fanconi syndrome (HP:0001994)2.11822619
93Proximal placement of thumb (HP:0009623)2.11476764
94Neoplasm of the oral cavity (HP:0100649)2.08972194
95Prominent nose (HP:0000448)2.08932314
96Horseshoe kidney (HP:0000085)2.08804475
97Abnormality of the renal collecting system (HP:0004742)2.07565045
98Short 4th metacarpal (HP:0010044)2.07178700
99Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.07178700
100Embryonal renal neoplasm (HP:0011794)2.06910622
101Atrophy/Degeneration involving motor neurons (HP:0007373)2.05864911
102Triphalangeal thumb (HP:0001199)2.04871978
103Aplasia/Hypoplasia of the sternum (HP:0006714)2.04368273
104Abnormality of the musculature of the pelvis (HP:0001469)2.03939355
105Abnormality of the hip-girdle musculature (HP:0001445)2.03939355
106Biliary tract neoplasm (HP:0100574)2.02939304
107Abnormality of aspartate family amino acid metabolism (HP:0010899)2.02540545
108Abnormality of the carotid arteries (HP:0005344)2.01221382
109Irregular epiphyses (HP:0010582)2.01071357
110Lymphoma (HP:0002665)1.98904832
111Shoulder girdle muscle weakness (HP:0003547)1.98847141
112Oligodactyly (hands) (HP:0001180)1.98447979
113Short thumb (HP:0009778)1.98315451
114Volvulus (HP:0002580)1.97832378
115Abnormal lung lobation (HP:0002101)1.96946325
116Megaloblastic anemia (HP:0001889)1.96540098
117Progressive inability to walk (HP:0002505)1.94781953
118Abnormality of the fingertips (HP:0001211)1.94339071
119Oligodactyly (HP:0012165)1.94038148
120Neoplasm of striated muscle (HP:0009728)1.93577632
121Cafe-au-lait spot (HP:0000957)1.92373399
122Increased nuchal translucency (HP:0010880)1.91908751
123Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)1.91669110
124Abnormal trabecular bone morphology (HP:0100671)1.90409872
125Malignant gastrointestinal tract tumors (HP:0006749)1.90327818
126Gastrointestinal carcinoma (HP:0002672)1.90327818
127Aplasia/hypoplasia of the humerus (HP:0006507)1.89116787
128Trismus (HP:0000211)1.89098485
129Cleft eyelid (HP:0000625)1.89005748
130Tongue fasciculations (HP:0001308)1.88570337
131Bifid tongue (HP:0010297)1.85613899
132Bile duct proliferation (HP:0001408)1.84611520
133Abnormal biliary tract physiology (HP:0012439)1.84611520
134Neoplasm of the adrenal gland (HP:0100631)1.84042072
135Abnormality of homocysteine metabolism (HP:0010919)1.83963851
136Homocystinuria (HP:0002156)1.83963851
137Squamous cell carcinoma (HP:0002860)1.82337033
138True hermaphroditism (HP:0010459)1.81744408
139Abnormality of serum amino acid levels (HP:0003112)1.80621063
140Neoplasm of the colon (HP:0100273)1.79653790
141Lactic acidosis (HP:0003128)1.78885890
142Abnormality of the calcaneus (HP:0008364)1.78672397
143Increased density of long bones (HP:0006392)1.78552067
144Missing ribs (HP:0000921)1.77334149
145Broad thumb (HP:0011304)1.76614345
146Hepatocellular necrosis (HP:0001404)1.76511146
147Sensory axonal neuropathy (HP:0003390)1.76159828
148Stenosis of the external auditory canal (HP:0000402)1.76011611
149Poor head control (HP:0002421)1.75986337
150Exertional dyspnea (HP:0002875)1.75618383
151Capillary hemangiomas (HP:0005306)1.75002590
152Neoplasm of the adrenal cortex (HP:0100641)1.73855791
153Abnormality of vitamin B metabolism (HP:0004340)1.73471412
154Abnormality of DNA repair (HP:0003254)1.73331651
155Congenital, generalized hypertrichosis (HP:0004540)1.73183960
156Aseptic necrosis (HP:0010885)1.72947259
157Anal stenosis (HP:0002025)1.72612685
158Nephroblastoma (Wilms tumor) (HP:0002667)1.71859435
159Pancreatic islet-cell hyperplasia (HP:0004510)1.71828404
160Hypoplastic labia majora (HP:0000059)1.71440495
161Macrocytic anemia (HP:0001972)1.70111302
162Abnormality of the vitamin B12 metabolism (HP:0004341)1.69581371
163Choanal atresia (HP:0000453)1.68122362
164Hepatic necrosis (HP:0002605)1.67765956
165Optic disc pallor (HP:0000543)1.64493227

Predicted kinase interactions (KEA)

RankGene SetZ-score
1NEK17.40393712
2NEK23.99213532
3BUB13.86927269
4CDC73.76399815
5WEE13.64073592
6TRIM282.73049095
7PLK42.66175704
8EIF2AK12.62539871
9SRPK12.54298824
10TSSK62.29511396
11EIF2AK32.21513027
12BMPR1B2.21323439
13TTK2.19907308
14BRSK22.14862558
15ACVR1B2.10758821
16MKNK12.00525769
17NUAK11.97910215
18PLK11.91666572
19TNIK1.83959197
20PLK31.78999926
21CDK121.78126650
22VRK21.74557797
23WNK31.68979748
24FRK1.66512293
25AURKB1.61710966
26ATR1.51514859
27CHEK21.49958490
28CDK71.45709081
29BCR1.42707847
30PASK1.39353433
31STK101.37037293
32TAF11.35111231
33BRSK11.32955772
34RPS6KB21.32121479
35STK161.28826557
36CHEK11.25013060
37TLK11.24564380
38NME11.23724566
39GRK11.23290421
40SCYL21.21348266
41RPS6KA41.20688135
42MKNK21.17891523
43VRK11.14477158
44CDK41.13544840
45MAP3K81.12828282
46EPHA21.11434470
47ZAK1.08766530
48MAP3K41.07995618
49AURKA1.04907415
50MAP3K101.01470325
51STK41.01468032
52EEF2K0.99931062
53STK390.98563587
54MAP4K20.97191466
55ADRBK20.95065225
56PIM10.92368939
57BRD40.91512575
58CDK20.89177440
59CSNK1G10.89025488
60DYRK30.87742454
61ATM0.86363209
62ALK0.85306072
63MAP4K10.80043226
64PIM20.79621393
65STK30.78880847
66PDK20.78635904
67TESK20.77688166
68NLK0.77202206
69OXSR10.76576623
70ERBB40.75589827
71LATS10.74982178
72NME20.74313710
73CDK60.73742957
74CSNK1G30.69263733
75CCNB10.68149285
76PAK40.67347633
77TGFBR10.65797489
78PLK20.64875325
79CDK10.64205818
80MAP3K110.63695967
81MELK0.62924120
82CSNK1A1L0.61860750
83CSNK1G20.61773845
84CASK0.60912897
85STK38L0.58952240
86TEC0.58462784
87SIK30.58361057
88EIF2AK20.56942991
89WNK40.55994746
90CSNK2A20.55671462
91LATS20.55132740
92PRKCI0.54978630
93STK240.54368959
94INSRR0.52012044
95KSR10.51373670
96AKT30.51013661
97MARK30.50611448
98RAF10.50406316
99CSNK2A10.48735379
100BRAF0.48210694
101MAP3K30.44925826
102PRKCE0.44523084
103ERBB30.41068643
104MAP3K120.40968803
105PINK10.40871238
106MAP2K70.40134454
107CAMKK20.40007988
108MTOR0.39910887
109JAK30.39417951
110CDK80.38521599
111FGFR10.37299067
112PAK10.36739921
113CHUK0.36243025
114RPS6KA50.35461572
115PNCK0.34709516
116CLK10.34386025
117CSNK1E0.33824907
118AKT20.32011456
119MAP2K30.31915558
120DYRK20.31892290
121TIE10.31813586
122ZAP700.31184533
123CDK30.31019917
124MST40.30098290
125MAPK140.29299293
126YES10.29109345
127PBK0.28158696
128PRKDC0.27562440
129FLT30.27327037
130RPS6KB10.26420215
131CSNK1D0.24921167
132TAOK20.24389647
133BTK0.20327656
134NEK90.20221797
135AKT10.19983900
136PKN20.19095885
137GSK3B0.17828105

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030304.91072038
2Mismatch repair_Homo sapiens_hsa034304.33526087
3* Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030084.13854664
4RNA transport_Homo sapiens_hsa030133.46984041
5Spliceosome_Homo sapiens_hsa030403.33587380
6Cell cycle_Homo sapiens_hsa041102.99824155
7RNA polymerase_Homo sapiens_hsa030202.97277097
8Base excision repair_Homo sapiens_hsa034102.92718431
9Homologous recombination_Homo sapiens_hsa034402.91907771
10One carbon pool by folate_Homo sapiens_hsa006702.89299188
11Protein export_Homo sapiens_hsa030602.81756976
12Nucleotide excision repair_Homo sapiens_hsa034202.75737216
13Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.53711097
14Proteasome_Homo sapiens_hsa030502.50702980
15Fanconi anemia pathway_Homo sapiens_hsa034602.35316053
16Pyrimidine metabolism_Homo sapiens_hsa002402.20487175
17Ribosome_Homo sapiens_hsa030102.15698649
18mRNA surveillance pathway_Homo sapiens_hsa030152.10290179
19RNA degradation_Homo sapiens_hsa030181.99674621
20Non-homologous end-joining_Homo sapiens_hsa034501.98947126
21Oxidative phosphorylation_Homo sapiens_hsa001901.96833837
22Basal transcription factors_Homo sapiens_hsa030221.94772190
23p53 signaling pathway_Homo sapiens_hsa041151.88223979
24Parkinsons disease_Homo sapiens_hsa050121.72810472
25Propanoate metabolism_Homo sapiens_hsa006401.69347133
26Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.50500097
27Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.37193370
28Pyruvate metabolism_Homo sapiens_hsa006201.36799442
29Epstein-Barr virus infection_Homo sapiens_hsa051691.31812915
30Huntingtons disease_Homo sapiens_hsa050161.25661036
31Steroid biosynthesis_Homo sapiens_hsa001001.25400414
32Purine metabolism_Homo sapiens_hsa002301.17945155
33Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.17828619
34Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.16957966
35Oocyte meiosis_Homo sapiens_hsa041141.15004329
36Viral carcinogenesis_Homo sapiens_hsa052031.13213393
37Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.10751275
38Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.08955771
39Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.08528706
40Systemic lupus erythematosus_Homo sapiens_hsa053221.08336640
41Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.05011800
42Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.01782026
43Antigen processing and presentation_Homo sapiens_hsa046121.01731988
44Herpes simplex infection_Homo sapiens_hsa051680.98989128
45Vitamin B6 metabolism_Homo sapiens_hsa007500.98252919
46Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.94385283
47Alzheimers disease_Homo sapiens_hsa050100.93256988
48HTLV-I infection_Homo sapiens_hsa051660.89800601
49MicroRNAs in cancer_Homo sapiens_hsa052060.88569998
50Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.82191633
51Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.79869791
52Thyroid cancer_Homo sapiens_hsa052160.78843992
53Fatty acid elongation_Homo sapiens_hsa000620.78409419
54Nitrogen metabolism_Homo sapiens_hsa009100.78159999
55Colorectal cancer_Homo sapiens_hsa052100.71944798
56Butanoate metabolism_Homo sapiens_hsa006500.71795036
57Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.70321644
58Small cell lung cancer_Homo sapiens_hsa052220.69732998
59Biosynthesis of amino acids_Homo sapiens_hsa012300.68526030
60Regulation of autophagy_Homo sapiens_hsa041400.68045343
61Legionellosis_Homo sapiens_hsa051340.66493888
62beta-Alanine metabolism_Homo sapiens_hsa004100.66253029
63Selenocompound metabolism_Homo sapiens_hsa004500.65701106
64Primary immunodeficiency_Homo sapiens_hsa053400.65413953
65Pentose phosphate pathway_Homo sapiens_hsa000300.63157582
66Caffeine metabolism_Homo sapiens_hsa002320.62250435
67Cysteine and methionine metabolism_Homo sapiens_hsa002700.61647705
68Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.61484265
69Circadian rhythm_Homo sapiens_hsa047100.61323978
70Metabolic pathways_Homo sapiens_hsa011000.61262639
71Transcriptional misregulation in cancer_Homo sapiens_hsa052020.59689316
72Tryptophan metabolism_Homo sapiens_hsa003800.59472923
73Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.59225567
74Drug metabolism - other enzymes_Homo sapiens_hsa009830.58607916
75TGF-beta signaling pathway_Homo sapiens_hsa043500.55788546
76Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.55347223
77Hippo signaling pathway_Homo sapiens_hsa043900.55124386
78Hepatitis B_Homo sapiens_hsa051610.54925826
79Sulfur metabolism_Homo sapiens_hsa009200.54518138
80Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.54210379
81Measles_Homo sapiens_hsa051620.53423066
82Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.53284821
83NF-kappa B signaling pathway_Homo sapiens_hsa040640.53181823
84Folate biosynthesis_Homo sapiens_hsa007900.53089758
85Apoptosis_Homo sapiens_hsa042100.53043488
86Vitamin digestion and absorption_Homo sapiens_hsa049770.52963526
87Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.52350731
88Phototransduction_Homo sapiens_hsa047440.52165888
89Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.51855956
90Glutathione metabolism_Homo sapiens_hsa004800.50908714
91Chronic myeloid leukemia_Homo sapiens_hsa052200.50319196
92Cyanoamino acid metabolism_Homo sapiens_hsa004600.49967332
93Shigellosis_Homo sapiens_hsa051310.47738700
94Maturity onset diabetes of the young_Homo sapiens_hsa049500.47154963
95Basal cell carcinoma_Homo sapiens_hsa052170.45937126
96Carbon metabolism_Homo sapiens_hsa012000.45553099
97Pentose and glucuronate interconversions_Homo sapiens_hsa000400.42015312
98Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.41978822
99HIF-1 signaling pathway_Homo sapiens_hsa040660.41122874
100Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.40400344
101mTOR signaling pathway_Homo sapiens_hsa041500.40376206
102Notch signaling pathway_Homo sapiens_hsa043300.40234271
103Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.39518238
104Alcoholism_Homo sapiens_hsa050340.38194502
105Viral myocarditis_Homo sapiens_hsa054160.38051714
106Peroxisome_Homo sapiens_hsa041460.37827437
107Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.37328059
108Cardiac muscle contraction_Homo sapiens_hsa042600.36880597
109NOD-like receptor signaling pathway_Homo sapiens_hsa046210.36769771
110Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.35173182
111Adherens junction_Homo sapiens_hsa045200.33673676
112Arginine and proline metabolism_Homo sapiens_hsa003300.33669405
113Influenza A_Homo sapiens_hsa051640.33638005
114Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.33100929
115Pathways in cancer_Homo sapiens_hsa052000.32427532
116Central carbon metabolism in cancer_Homo sapiens_hsa052300.31397881
117Ether lipid metabolism_Homo sapiens_hsa005650.31092604
118N-Glycan biosynthesis_Homo sapiens_hsa005100.30786632
119Hedgehog signaling pathway_Homo sapiens_hsa043400.30675136
120Bladder cancer_Homo sapiens_hsa052190.30113531
121Prostate cancer_Homo sapiens_hsa052150.29451347
122Pancreatic cancer_Homo sapiens_hsa052120.28934994
123Fatty acid metabolism_Homo sapiens_hsa012120.28863571
124Acute myeloid leukemia_Homo sapiens_hsa052210.28168671
1252-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.27737340
126Hematopoietic cell lineage_Homo sapiens_hsa046400.27156196
127T cell receptor signaling pathway_Homo sapiens_hsa046600.26412156
128Non-small cell lung cancer_Homo sapiens_hsa052230.25825647
129Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.25541792
130RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.25387101
131Type I diabetes mellitus_Homo sapiens_hsa049400.24214064
132Olfactory transduction_Homo sapiens_hsa047400.24008676
133Thyroid hormone signaling pathway_Homo sapiens_hsa049190.23571013
134Intestinal immune network for IgA production_Homo sapiens_hsa046720.23342539
135Linoleic acid metabolism_Homo sapiens_hsa005910.22158022
136FoxO signaling pathway_Homo sapiens_hsa040680.21771798
137Wnt signaling pathway_Homo sapiens_hsa043100.20821993
138Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.19854890
139Endometrial cancer_Homo sapiens_hsa052130.19776069
140Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.18842047
141Lysine degradation_Homo sapiens_hsa003100.18374197
142Fatty acid biosynthesis_Homo sapiens_hsa000610.17998936
143Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.17509021
144Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.17021677
145Primary bile acid biosynthesis_Homo sapiens_hsa001200.16920683
146Sulfur relay system_Homo sapiens_hsa041220.16913019
147Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.16602236
148Fructose and mannose metabolism_Homo sapiens_hsa000510.14543828
149Neurotrophin signaling pathway_Homo sapiens_hsa047220.14427926
150Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.13977591
151Melanoma_Homo sapiens_hsa052180.13884307
152Jak-STAT signaling pathway_Homo sapiens_hsa046300.13416372
153Leishmaniasis_Homo sapiens_hsa051400.13383711
154Fatty acid degradation_Homo sapiens_hsa000710.13238621

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