UTS2R

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1transcription from mitochondrial promoter (GO:0006390)8.73014832
2proline metabolic process (GO:0006560)7.95477544
3embryonic process involved in female pregnancy (GO:0060136)7.77690142
4replication fork processing (GO:0031297)7.77368739
5lymph vessel development (GO:0001945)7.37456044
6positive regulation of protein homooligomerization (GO:0032464)6.83723623
7cellular hyperosmotic response (GO:0071474)6.74769242
8maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)6.43832694
9regulation of integrin activation (GO:0033623)6.20233261
10oxidative demethylation (GO:0070989)5.96281530
11regulation of protein homooligomerization (GO:0032462)5.87253219
12establishment of apical/basal cell polarity (GO:0035089)5.77564805
13DNA deamination (GO:0045006)5.67889591
14mitochondrial DNA metabolic process (GO:0032042)5.58697662
15poly(A)+ mRNA export from nucleus (GO:0016973)5.48945502
16muscle cell fate commitment (GO:0042693)5.35778603
17regulation of response to osmotic stress (GO:0047484)5.13026799
18DNA strand renaturation (GO:0000733)5.04944071
19establishment of monopolar cell polarity (GO:0061162)5.03227286
20establishment or maintenance of monopolar cell polarity (GO:0061339)5.03227286
21somatic diversification of immune receptors via somatic mutation (GO:0002566)5.00574991
22somatic hypermutation of immunoglobulin genes (GO:0016446)5.00574991
23negative regulation of JAK-STAT cascade (GO:0046426)4.87136537
24establishment of protein localization to mitochondrial membrane (GO:0090151)4.73355271
25mitotic G1 DNA damage checkpoint (GO:0031571)4.67431466
26negative regulation of fatty acid biosynthetic process (GO:0045717)4.66091745
27negative regulation of cell cycle arrest (GO:0071157)4.62776958
28positive regulation of hair follicle development (GO:0051798)4.62428651
29positive regulation of hair cycle (GO:0042635)4.62428651
30regulation of mammary gland epithelial cell proliferation (GO:0033599)4.61861947
31heterochromatin organization (GO:0070828)4.56917976
32embryonic placenta development (GO:0001892)4.54334056
33DNA integration (GO:0015074)4.43379022
34labyrinthine layer development (GO:0060711)4.43063980
35positive regulation of myotube differentiation (GO:0010831)4.41087614
36regulation of apoptotic process involved in morphogenesis (GO:1902337)4.39958711
37negative regulation of Ras GTPase activity (GO:0034261)4.37483506
38G1 DNA damage checkpoint (GO:0044783)4.35864862
39cellular response to ATP (GO:0071318)4.34356999
40viral mRNA export from host cell nucleus (GO:0046784)4.34213133
41formation of translation preinitiation complex (GO:0001731)4.20407515
42L-serine metabolic process (GO:0006563)4.17373704
43regulation of translational fidelity (GO:0006450)4.13306342
44diaphragm development (GO:0060539)4.10455903
45mitotic G1/S transition checkpoint (GO:0044819)4.09611113
46glutamine family amino acid biosynthetic process (GO:0009084)3.98057486
47DNA double-strand break processing (GO:0000729)3.97608561
48mRNA cleavage (GO:0006379)3.96590718
49regulation of sister chromatid cohesion (GO:0007063)3.95918369
50regulation of glucocorticoid metabolic process (GO:0031943)3.90913727
51negative regulation of myeloid cell apoptotic process (GO:0033033)3.89789033
52tooth mineralization (GO:0034505)3.88989161
53regulation of cAMP-dependent protein kinase activity (GO:2000479)3.88510309
54positive regulation of mitotic sister chromatid separation (GO:1901970)3.87377536
55positive regulation of mitotic metaphase/anaphase transition (GO:0045842)3.87377536
56positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)3.87377536
57negative regulation of protein oligomerization (GO:0032460)3.86321896
58regulation of glucose import in response to insulin stimulus (GO:2001273)3.86168459
59DNA unwinding involved in DNA replication (GO:0006268)3.85330423
60base-excision repair (GO:0006284)3.83756618
61positive regulation by host of viral transcription (GO:0043923)3.81397465
62convergent extension (GO:0060026)3.79553349
63embryonic camera-type eye development (GO:0031076)3.77990394
64skeletal muscle organ development (GO:0060538)3.72610204
65glial cell migration (GO:0008347)3.72577737
66NIK/NF-kappaB signaling (GO:0038061)3.71394194
67regulation of double-strand break repair via homologous recombination (GO:0010569)3.69481021
68face development (GO:0060324)3.69444695
69positive regulation of protein oligomerization (GO:0032461)3.69131206
70maturation of 5.8S rRNA (GO:0000460)3.67912033
71spliceosomal tri-snRNP complex assembly (GO:0000244)3.66949986
72regulation of RNA export from nucleus (GO:0046831)3.66416217
73positive regulation of DNA repair (GO:0045739)3.65642929
74histone H4-K12 acetylation (GO:0043983)3.63054859
75trophectodermal cell differentiation (GO:0001829)3.59364783
76regulation of protein oligomerization (GO:0032459)3.56296909
77double-strand break repair via nonhomologous end joining (GO:0006303)3.56172084
78non-recombinational repair (GO:0000726)3.56172084
79meiotic chromosome segregation (GO:0045132)3.54035086
80regulation of glucocorticoid secretion (GO:2000849)3.49714009
81regulation of NFAT protein import into nucleus (GO:0051532)3.48438106
82negative regulation of erythrocyte differentiation (GO:0045647)3.47897869
83positive regulation of developmental pigmentation (GO:0048087)3.44118261
84mitochondrial RNA metabolic process (GO:0000959)3.43250943
85embryonic heart tube development (GO:0035050)3.39752891
86regulation of nuclear cell cycle DNA replication (GO:0033262)3.38986853
87base-excision repair, AP site formation (GO:0006285)3.38320830
88regulation of double-strand break repair (GO:2000779)3.37832427
89positive regulation of protein sumoylation (GO:0033235)3.36988875
90negative regulation of mRNA splicing, via spliceosome (GO:0048025)3.35966351
91negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471)3.35615706
92dosage compensation (GO:0007549)3.32790636
93chromosome condensation (GO:0030261)3.31350147
94negative regulation of appetite (GO:0032099)3.29373343
95negative regulation of response to food (GO:0032096)3.29373343
96DNA demethylation (GO:0080111)3.28460227
97regulation of hair follicle development (GO:0051797)3.27501771
98kinetochore assembly (GO:0051382)3.24877115
99DNA replication initiation (GO:0006270)3.23819222
100outer ear morphogenesis (GO:0042473)3.23745167
101intracellular estrogen receptor signaling pathway (GO:0030520)3.23380390
102pyrimidine deoxyribonucleotide catabolic process (GO:0009223)3.21752265
103regulation of cell size (GO:0008361)3.20537435
104planar cell polarity pathway involved in neural tube closure (GO:0090179)3.19517746
105gonadal mesoderm development (GO:0007506)3.19290946
106protein targeting to lysosome (GO:0006622)3.19204687
107establishment of protein localization to vacuole (GO:0072666)3.19204687
108protein targeting to vacuole (GO:0006623)3.19204687
109nodal signaling pathway (GO:0038092)3.19202943
110respiratory system process (GO:0003016)3.19161492
111telomere maintenance via semi-conservative replication (GO:0032201)3.18288100
112peptidyl-arginine omega-N-methylation (GO:0035247)3.18248064
113auditory receptor cell stereocilium organization (GO:0060088)3.17468448
114positive regulation of interferon-gamma biosynthetic process (GO:0045078)3.17399061
115mitotic cell cycle arrest (GO:0071850)3.17367794
116negative regulation of heart rate (GO:0010459)3.17004068
117activation of Rac GTPase activity (GO:0032863)3.16731006
118protein-DNA complex disassembly (GO:0032986)3.15871893
119nucleosome disassembly (GO:0006337)3.15871893
120DNA topological change (GO:0006265)3.15678616
121nucleotide-excision repair, DNA gap filling (GO:0006297)3.15062879
122cellular response to zinc ion (GO:0071294)3.13918875
123regulation of early endosome to late endosome transport (GO:2000641)3.12460354
124negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665)3.11241097
125regulation of interferon-beta biosynthetic process (GO:0045357)3.10856501
126positive regulation of receptor recycling (GO:0001921)3.10740052
127GDP-mannose metabolic process (GO:0019673)3.10271714
128negative regulation of mRNA processing (GO:0050686)3.09382265
129positive regulation of chromosome segregation (GO:0051984)3.09375054
130apoptotic process involved in morphogenesis (GO:0060561)3.09319797
131cell migration in hindbrain (GO:0021535)3.09184361
132regulation of branching involved in prostate gland morphogenesis (GO:0060687)3.09024689
133nuclear envelope reassembly (GO:0031468)3.07692023
134mitotic nuclear envelope reassembly (GO:0007084)3.07692023
135regulation of chromatin binding (GO:0035561)3.04189508
136mitotic sister chromatid segregation (GO:0000070)3.03998442
137positive regulation of transcription initiation from RNA polymerase II promoter (GO:0060261)3.02785614
138regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.02488287
139response to inactivity (GO:0014854)3.02089235
140regulation of mitochondrial depolarization (GO:0051900)3.01914842
141termination of RNA polymerase II transcription (GO:0006369)3.01083350
142regulation of myeloid cell apoptotic process (GO:0033032)3.00935637
143embryonic eye morphogenesis (GO:0048048)3.00913762
144DNA replication checkpoint (GO:0000076)2.99621386
145adenosine receptor signaling pathway (GO:0001973)2.98970954
146alkaloid metabolic process (GO:0009820)2.98363491
147negative regulation of toll-like receptor signaling pathway (GO:0034122)2.97027506
148negative regulation of calcium ion transport into cytosol (GO:0010523)2.95948079
149regulation of corticosteroid hormone secretion (GO:2000846)2.95018204
150chromatin silencing (GO:0006342)2.92466907
151outflow tract septum morphogenesis (GO:0003148)2.92451048
152negative regulation of cell aging (GO:0090344)2.90305151
153activation of MAPKKK activity (GO:0000185)2.89513955
154cochlea morphogenesis (GO:0090103)2.88657145
155regulation of uterine smooth muscle contraction (GO:0070472)2.88310873
156cardiac muscle cell proliferation (GO:0060038)2.87602592
157regulation of interferon-gamma biosynthetic process (GO:0045072)2.85259006
158cranial nerve morphogenesis (GO:0021602)2.84272775
159modulation by symbiont of host cellular process (GO:0044068)2.83908780
160histone arginine methylation (GO:0034969)2.83416619
161regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)2.81601348
162coronary vasculature morphogenesis (GO:0060977)2.78493403
163modulation by virus of host process (GO:0019054)2.74779951
164mammary gland epithelial cell differentiation (GO:0060644)2.72588371
165muscle organ morphogenesis (GO:0048644)2.71585151
166DNA packaging (GO:0006323)2.71525682
167protein localization to chromosome, centromeric region (GO:0071459)2.71474437
168RNA stabilization (GO:0043489)2.71309594
169mRNA stabilization (GO:0048255)2.71309594
170negative regulation of histone methylation (GO:0031061)2.68989457
171thyroid gland development (GO:0030878)2.68770324
172mitochondrial genome maintenance (GO:0000002)2.68264431
173regulation of somitogenesis (GO:0014807)2.67958896
174striated muscle cell proliferation (GO:0014855)2.67548720
175positive regulation of mast cell degranulation (GO:0043306)2.67488090
176positive regulation of mast cell activation involved in immune response (GO:0033008)2.67488090
177embryonic skeletal joint morphogenesis (GO:0060272)2.63046744
178RNA localization (GO:0006403)2.61386322
179negative regulation of interleukin-8 production (GO:0032717)2.61003872
1803-UTR-mediated mRNA stabilization (GO:0070935)2.58430612
181CD4-positive or CD8-positive, alpha-beta T cell lineage commitment (GO:0043369)2.57954907
182regulation of vitamin D biosynthetic process (GO:0060556)2.56284176
183negative regulation of Notch signaling pathway (GO:0045746)2.55543927
184peptidyl-arginine N-methylation (GO:0035246)2.54148112
185peptidyl-arginine methylation (GO:0018216)2.54148112
186regulation of type I interferon-mediated signaling pathway (GO:0060338)2.53074476
187positive thymic T cell selection (GO:0045059)2.51657245
188regulation of secondary heart field cardioblast proliferation (GO:0003266)2.49691898
189regulation of cardioblast proliferation (GO:0003264)2.49691898
190negative regulation of striated muscle cell differentiation (GO:0051154)2.49367141
191hyperosmotic response (GO:0006972)2.47694399
192positive regulation of leukocyte apoptotic process (GO:2000108)2.46492003
193chromatin assembly (GO:0031497)2.46063387
194DNA strand elongation involved in DNA replication (GO:0006271)2.43752953
195proline biosynthetic process (GO:0006561)10.2507849

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1SMAD1_18555785_ChIP-Seq_MESCs_Mouse3.68535042
2RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse3.49175648
3ZFP281_18358816_ChIP-ChIP_MESCs_Mouse3.47637038
4KLF2_18264089_ChIP-ChIP_MESCs_Mouse3.46845183
5KLF5_18264089_ChIP-ChIP_MESCs_Mouse3.46845183
6KLF4_18264089_ChIP-ChIP_MESCs_Mouse3.46845183
7SMAD3_22036565_ChIP-Seq_ESCs_Mouse3.22197673
8NANOG_18700969_ChIP-ChIP_MESCs_Mouse2.96932929
9SOX2_18358816_ChIP-ChIP_MESCs_Mouse2.92103301
10E2F7_22180533_ChIP-Seq_HELA_Human2.90981086
11NACC1_18358816_ChIP-ChIP_MESCs_Mouse2.80995691
12TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse2.61417196
13POU5F1_16518401_ChIP-PET_MESCs_Mouse2.58353247
14TCF3_18692474_ChIP-Seq_MESCs_Mouse2.49943217
15ERG_21242973_ChIP-ChIP_JURKAT_Human2.39491613
16KDM2B_26808549_Chip-Seq_SIL-ALL_Human2.38836022
17DACH1_20351289_ChIP-Seq_MDA-MB-231_Human2.29495275
18MYC_18555785_ChIP-Seq_MESCs_Mouse2.29168772
19SALL4_18804426_ChIP-ChIP_MESCs_Mouse2.28188973
20CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human2.25881645
21P68_20966046_ChIP-Seq_HELA_Human2.22910403
22TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat2.21759850
23KLF4_18358816_ChIP-ChIP_MESCs_Mouse2.20147501
24NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human2.20124034
25E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human2.15864261
26TCF3_18692474_ChIP-Seq_MEFs_Mouse2.11701110
27ELK3_25401928_ChIP-Seq_HUVEC_Human2.11652072
28MYC_19079543_ChIP-ChIP_MESCs_Mouse2.09729490
29NR0B1_18358816_ChIP-ChIP_MESCs_Mouse2.05826674
30POU5F1_18700969_ChIP-ChIP_MESCs_Mouse2.03314902
31VDR_21846776_ChIP-Seq_THP-1_Human2.00063357
32EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.95797989
33THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.94087612
34* NANOG_18347094_ChIP-ChIP_MESCs_Mouse1.93778453
35NANOG_21062744_ChIP-ChIP_HESCs_Human1.93541967
36TCF7_22412390_ChIP-Seq_EML_Mouse1.87818807
37ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.86831456
38LXR_22292898_ChIP-Seq_THP-1_Human1.84113419
39VDR_24763502_ChIP-Seq_THP-1_Human1.83286870
40MAF_26560356_Chip-Seq_TH2_Human1.82305084
41STAT3_1855785_ChIP-Seq_MESCs_Mouse1.78311122
42KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.77062412
43* PU.1_20513432_ChIP-Seq_Bcells_Mouse1.72950464
44STAT6_21828071_ChIP-Seq_BEAS2B_Human1.72726468
45SA1_27219007_Chip-Seq_ERYTHROID_Human1.70933000
46MYC_18358816_ChIP-ChIP_MESCs_Mouse1.69584148
47ELF1_20517297_ChIP-Seq_JURKAT_Human1.68886420
48CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.68748508
49SALL1_21062744_ChIP-ChIP_HESCs_Human1.67806877
50BCL6_27268052_Chip-Seq_Bcells_Human1.65441446
51MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.61732225
52NANOG_18555785_ChIP-Seq_MESCs_Mouse1.60484636
53POU5F1_18692474_ChIP-Seq_MESCs_Mouse1.60129499
54MAF_26560356_Chip-Seq_TH1_Human1.60080574
55XRN2_22483619_ChIP-Seq_HELA_Human1.59523648
56RARG_19884340_ChIP-ChIP_MEFs_Mouse1.59058377
57SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.58122281
58BCOR_27268052_Chip-Seq_Bcells_Human1.57886938
59* NANOG_18358816_ChIP-ChIP_MESCs_Mouse1.57226850
60UTX_26944678_Chip-Seq_JUKART_Human1.56947593
61RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.56913183
62TET1_21451524_ChIP-Seq_MESCs_Mouse1.55184854
63* EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.53697199
64ESR1_15608294_ChIP-ChIP_MCF-7_Human1.52627786
65* NANOG_18692474_ChIP-Seq_MESCs_Mouse1.52185065
66PRDM14_21183938_ChIP-Seq_MESCs_Mouse1.51628008
67ZFP281_27345836_Chip-Seq_ESCs_Mouse1.50872633
68KDM2B_26808549_Chip-Seq_JURKAT_Human1.49993061
69SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.49825377
70ZFP281_18757296_ChIP-ChIP_E14_Mouse1.48384769
71SMC4_20622854_ChIP-Seq_HELA_Human1.48278987
72ZNF263_19887448_ChIP-Seq_K562_Human1.47490570
73POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.46917642
74SRY_22984422_ChIP-ChIP_TESTIS_Rat1.46438690
75KLF4_18555785_ChIP-Seq_MESCs_Mouse1.44884115
76FOXM1_23109430_ChIP-Seq_U2OS_Human1.44687821
77RACK7_27058665_Chip-Seq_MCF-7_Human1.43570098
78* CTCF_27219007_Chip-Seq_Bcells_Human1.40050678
79STAT3_19079543_ChIP-ChIP_MESCs_Mouse1.38748712
80SOX2_18692474_ChIP-Seq_MESCs_Mouse1.38650370
81MYC_19030024_ChIP-ChIP_MESCs_Mouse1.38214626
82NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.38075444
83CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.37501514
84CTCF_21964334_Chip-Seq_Bcells_Human1.36792608
85RXRA_24833708_ChIP-Seq_LIVER_Mouse1.36710797
86YY1_21170310_ChIP-Seq_MESCs_Mouse1.34560530
87HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.34378567
88RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.33835940
89* TCF3_18347094_ChIP-ChIP_MESCs_Mouse1.32306452
90CREB1_26743006_Chip-Seq_LNCaP_Human1.29196953
91SOX2_18692474_ChIP-Seq_MEFs_Mouse1.29001468
92MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human1.28493005
93NANOG_16518401_ChIP-PET_MESCs_Mouse1.28446246
94SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.28350854
95EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.27997143
96THAP11_20581084_ChIP-Seq_MESCs_Mouse1.27401131
97* SPI1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.27343449
98* ETS1_21867929_ChIP-Seq_TH2_Mouse1.26817887
99TP63_17297297_ChIP-ChIP_HaCaT_Human1.26756148
100SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.26352698
101TP53_20018659_ChIP-ChIP_R1E_Mouse1.25039761
102SPI1_26923725_Chip-Seq_HPCs_Mouse1.25021585
103NCOR1_26117541_ChIP-Seq_K562_Human1.23549423
104PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.22756240
105CIITA_25753668_ChIP-Seq_RAJI_Human1.21841258
106* DNAJC2_21179169_ChIP-ChIP_NT2_Human1.21830591
107IRF8_22096565_ChIP-ChIP_GC-B_Human1.21752643
108UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.19353272
109CTCF_26484167_Chip-Seq_Bcells_Mouse1.19306036
110HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.17654434
111RARB_24833708_ChIP-Seq_LIVER_Mouse1.17068236
112SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.16463003
113MYCN_18555785_ChIP-Seq_MESCs_Mouse1.16045632
114JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.15863131
115SOX2_18555785_ChIP-Seq_MESCs_Mouse1.15848250
116OCT4_18692474_ChIP-Seq_MEFs_Mouse1.15757204
117KDM2B_26808549_Chip-Seq_SUP-B15_Human1.15159378
118SA1_27219007_Chip-Seq_Bcells_Human1.14900717
119* BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.14609270
120E2F1_18555785_ChIP-Seq_MESCs_Mouse1.12301633
121FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.11988998
122NANOG_18692474_ChIP-Seq_MEFs_Mouse1.11363156
123CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.10333526
124CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.09216112
125KAP1_27257070_Chip-Seq_ESCs_Mouse1.08491894
126SETDB1_19884255_ChIP-Seq_MESCs_Mouse1.08253115
127TP53_22127205_ChIP-Seq_IMR90_Human1.08030125
128FOXP1_21924763_ChIP-Seq_HESCs_Human1.07993416
129DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.06081916
130POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.05710326
131EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.04802327
132ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.04609826
133CTCF_21964334_ChIP-Seq_BJAB-B_Human1.04406989
134RARA_24833708_ChIP-Seq_LIVER_Mouse1.03832639
135KDM2B_26808549_Chip-Seq_DND41_Human1.03595395
136POU5F1_18347094_ChIP-ChIP_MESCs_Mouse1.03123682
137CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.02845051
138P300_27058665_Chip-Seq_ZR-75-30cells_Human1.02544414
139STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.02270123
140BRD4_27068464_Chip-Seq_AML-cells_Mouse1.01586234
141PHF8_20622854_ChIP-Seq_HELA_Human1.00865708
142TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.00729552
143TP63_19390658_ChIP-ChIP_HaCaT_Human1.00618167
144JARID1B-DAIN_22020125_ChIP-Seq_ESCs_Mouse1.00296084
145CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.00057520
146STAT1_20625510_ChIP-Seq_HELA_Human1.00033708
147CTCF_27219007_Chip-Seq_ERYTHROID_Human0.99588474
148RING1B_27294783_Chip-Seq_NPCs_Mouse0.99274031
149E2F1_20622854_ChIP-Seq_HELA_Human0.99224330
150RUNX1_22412390_ChIP-Seq_EML_Mouse0.99009363
151CTCF_20526341_ChIP-Seq_ESCs_Human0.98684630
152TAL1_20887958_ChIP-Seq_HPC-7_Mouse0.98644654
153KDM2B_26808549_Chip-Seq_K562_Human0.98141551
154MYC_22102868_ChIP-Seq_BL_Human0.98053382
155KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.97883377
156GATA1_22383799_ChIP-Seq_G1ME_Mouse0.97327847
157CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.97189742
158YY1_22570637_ChIP-Seq_MALME-3M_Human0.96252040
159ZNF652_21678463_ChIP-ChIP_ZR75-1_Human0.95684170
160* TP63_22573176_ChIP-Seq_HFKS_Human0.93441138
161CTCF_18555785_ChIP-Seq_MESCs_Mouse0.93362712

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008057_abnormal_DNA_replication6.29309798
2MP0001346_abnormal_lacrimal_gland4.75089540
3MP0005171_absent_coat_pigmentation4.69126348
4MP0002163_abnormal_gland_morphology4.49106363
5MP0005623_abnormal_meninges_morphology4.33604394
6MP0009278_abnormal_bone_marrow4.08095167
7MP0010030_abnormal_orbit_morphology4.00708877
8MP0003303_peritoneal_inflammation3.97030931
9MP0004233_abnormal_muscle_weight3.62123821
10MP0002009_preneoplasia3.17306923
11MP0005379_endocrine/exocrine_gland_phen2.90925137
12MP0005451_abnormal_body_composition2.71157544
13MP0004858_abnormal_nervous_system2.65148093
14MP0003890_abnormal_embryonic-extraembry2.52151554
15MP0002653_abnormal_ependyma_morphology2.51224258
16MP0004510_myositis2.49304791
17MP0000733_abnormal_muscle_development2.45046687
18MP0008995_early_reproductive_senescence2.36510345
19MP0003283_abnormal_digestive_organ2.30515747
20MP0010094_abnormal_chromosome_stability2.27574230
21MP0002877_abnormal_melanocyte_morpholog2.22940356
22MP0006072_abnormal_retinal_apoptosis2.20555896
23MP0004133_heterotaxia2.12616052
24MP0008877_abnormal_DNA_methylation2.08766894
25MP0002249_abnormal_larynx_morphology2.04712936
26MP0000678_abnormal_parathyroid_gland2.02485180
27MP0000579_abnormal_nail_morphology2.01302771
28MP0001545_abnormal_hematopoietic_system2.00285031
29MP0005397_hematopoietic_system_phenotyp2.00285031
30MP0003119_abnormal_digestive_system1.95209159
31MP0003786_premature_aging1.93026914
32MP0005076_abnormal_cell_differentiation1.93012704
33MP0003453_abnormal_keratinocyte_physiol1.91992114
34MP0004957_abnormal_blastocyst_morpholog1.85082801
35MP0002234_abnormal_pharynx_morphology1.83674649
36MP0002269_muscular_atrophy1.83031338
37MP0005670_abnormal_white_adipose1.79749186
38MP0000685_abnormal_immune_system1.76103302
39MP0003718_maternal_effect1.73400459
40MP0005387_immune_system_phenotype1.70913397
41MP0001790_abnormal_immune_system1.70913397
42MP0005666_abnormal_adipose_tissue1.67150775
43MP0002084_abnormal_developmental_patter1.63966756
44MP0002282_abnormal_trachea_morphology1.61297631
45MP0002086_abnormal_extraembryonic_tissu1.54854295
46MP0002332_abnormal_exercise_endurance1.52386149
47MP0005410_abnormal_fertilization1.51653154
48MP0001293_anophthalmia1.51066241
49MP0003111_abnormal_nucleus_morphology1.50290202
50MP0009333_abnormal_splenocyte_physiolog1.49812989
51MP0008058_abnormal_DNA_repair1.49220186
52MP0001697_abnormal_embryo_size1.48819443
53MP0000003_abnormal_adipose_tissue1.48760659
54MP0003091_abnormal_cell_migration1.48669648
55MP0005423_abnormal_somatic_nervous1.48510295
56MP0008932_abnormal_embryonic_tissue1.43998192
57MP0010307_abnormal_tumor_latency1.43414824
58MP0002254_reproductive_system_inflammat1.42573719
59MP0005375_adipose_tissue_phenotype1.42381975
60MP0000681_abnormal_thyroid_gland1.41850886
61MP0002085_abnormal_embryonic_tissue1.41689966
62MP0005310_abnormal_salivary_gland1.41129918
63MP0010352_gastrointestinal_tract_polyps1.39003777
64MP0003705_abnormal_hypodermis_morpholog1.35184466
65MP0000759_abnormal_skeletal_muscle1.33397878
66MP0005174_abnormal_tail_pigmentation1.31924733
67MP0004197_abnormal_fetal_growth/weight/1.31349031
68MP0001348_abnormal_lacrimal_gland1.29624691
69MP0003567_abnormal_fetal_cardiomyocyte1.29594376
70MP0002796_impaired_skin_barrier1.28942897
71MP0005380_embryogenesis_phenotype1.28737481
72MP0001672_abnormal_embryogenesis/_devel1.28737481
73MP0003436_decreased_susceptibility_to1.27993629
74MP0000747_muscle_weakness1.27916985
75MP0000462_abnormal_digestive_system1.26130309
76MP0009840_abnormal_foam_cell1.25352750
77MP0005000_abnormal_immune_tolerance1.25190476
78MP0003828_pulmonary_edema1.24399347
79MP0003693_abnormal_embryo_hatching1.24282121
80MP0001340_abnormal_eyelid_morphology1.23161142
81MP0000762_abnormal_tongue_morphology1.20697868
82MP0000470_abnormal_stomach_morphology1.20606099
83MP0000858_altered_metastatic_potential1.19898954
84MP0001835_abnormal_antigen_presentation1.18847320
85MP0000751_myopathy1.18532145
86MP0003755_abnormal_palate_morphology1.17067770
87MP0000750_abnormal_muscle_regeneration1.16171913
88MP0003137_abnormal_impulse_conducting1.15331164
89MP0000639_abnormal_adrenal_gland1.14690522
90MP0003077_abnormal_cell_cycle1.14389413
91MP0001986_abnormal_taste_sensitivity1.12082129
92MP0009053_abnormal_anal_canal1.11614149
93MP0001800_abnormal_humoral_immune1.10475434
94MP0003172_abnormal_lysosome_physiology1.10354920
95MP0002060_abnormal_skin_morphology1.09967158
96MP0002111_abnormal_tail_morphology1.09770500
97MP0005671_abnormal_response_to1.08728231
98MP0001188_hyperpigmentation1.08110730
99MP0002452_abnormal_antigen_presenting1.07039615
100MP0002148_abnormal_hypersensitivity_rea1.06924422
101MP0005266_abnormal_metabolism1.06728676
102MP0000490_abnormal_crypts_of1.05763019
103MP0004142_abnormal_muscle_tone1.05370253
104MP0003136_yellow_coat_color1.04502733
105MP0002398_abnormal_bone_marrow1.03735081
106MP0004087_abnormal_muscle_fiber1.03152948
107MP0001873_stomach_inflammation1.02892183
108MP0002114_abnormal_axial_skeleton1.01020143
109MP0004808_abnormal_hematopoietic_stem0.99782049
110MP0003935_abnormal_craniofacial_develop0.99194309
111MP0001270_distended_abdomen0.99037501
112MP0000350_abnormal_cell_proliferation0.97210376
113MP0002108_abnormal_muscle_morphology0.96782964
114MP0001730_embryonic_growth_arrest0.96367515
115MP0005409_darkened_coat_color0.95340059
116MP0004264_abnormal_extraembryonic_tissu0.93612283
117MP0005330_cardiomyopathy0.93475864
118MP0002932_abnormal_joint_morphology0.93121022
119MP0002723_abnormal_immune_serum0.92942386
120MP0000432_abnormal_head_morphology0.90035376
121MP0003045_fibrosis0.89986125
122MP0000015_abnormal_ear_pigmentation0.89880681
123MP0000703_abnormal_thymus_morphology0.89468061
124MP0003984_embryonic_growth_retardation0.89052130
125MP0002722_abnormal_immune_system0.88939595
126MP0003763_abnormal_thymus_physiology0.88297524
127MP0009115_abnormal_fat_cell0.87354618
128MP0002116_abnormal_craniofacial_bone0.86845972
129MP0000313_abnormal_cell_death0.86224960
130MP0000566_synostosis0.86161651
131MP0000371_diluted_coat_color0.86127663
132MP0002088_abnormal_embryonic_growth/wei0.84704438
133MP0002080_prenatal_lethality0.84534127
134MP0001919_abnormal_reproductive_system0.83847105
135MP0005075_abnormal_melanosome_morpholog0.83558787
136MP0000716_abnormal_immune_system0.83429664
137MP0002396_abnormal_hematopoietic_system0.82280195
138MP0000516_abnormal_urinary_system0.82190666
139MP0005367_renal/urinary_system_phenotyp0.82190666
140MP0002405_respiratory_system_inflammati0.81585488
141MP0005085_abnormal_gallbladder_physiolo0.80929215
142MP0002089_abnormal_postnatal_growth/wei0.80479085
143MP0005220_abnormal_exocrine_pancreas0.79895980
144MP0000689_abnormal_spleen_morphology0.79809018
145MP0002429_abnormal_blood_cell0.79798148
146MP0000049_abnormal_middle_ear0.79410798
147MP0002106_abnormal_muscle_physiology0.78991204
148MP0005501_abnormal_skin_physiology0.77957482
149MP0003646_muscle_fatigue0.77447221
150MP0003699_abnormal_female_reproductive0.75731506
151MP0004185_abnormal_adipocyte_glucose0.74576051
152MP0009250_abnormal_appendicular_skeleto0.73904005
153MP0005395_other_phenotype0.73561891
154MP0002420_abnormal_adaptive_immunity0.73312875
155MP0001145_abnormal_male_reproductive0.72937642
156MP0001819_abnormal_immune_cell0.72670758
157MP0010630_abnormal_cardiac_muscle0.71913333
158MP0005508_abnormal_skeleton_morphology0.71350363
159MP0004019_abnormal_vitamin_homeostasis0.70930558
160MP0002075_abnormal_coat/hair_pigmentati0.70868759
161MP0005369_muscle_phenotype0.70263922
162MP0003448_altered_tumor_morphology0.68899602
163MP0000767_abnormal_smooth_muscle0.68606240
164MP0003941_abnormal_skin_development0.68526852
165MP0002019_abnormal_tumor_incidence0.68409629
166MP0000955_abnormal_spinal_cord0.66983210
167MP0005025_abnormal_response_to0.65917523
168MP0003936_abnormal_reproductive_system0.65806715
169MP0003385_abnormal_body_wall0.65238045
170MP0000467_abnormal_esophagus_morphology0.64319212
171MP0005645_abnormal_hypothalamus_physiol0.62790920
172MP0005058_abnormal_lysosome_morphology0.62720238
173MP0001186_pigmentation_phenotype0.61020452
174MP0003300_gastrointestinal_ulcer0.60850926

Predicted human phenotypes

RankGene SetZ-score
1Concave nail (HP:0001598)5.68401571
2Rib fusion (HP:0000902)5.38402740
3Facial hemangioma (HP:0000329)5.11227755
4Hypochromic microcytic anemia (HP:0004840)5.05234156
5Annular pancreas (HP:0001734)4.78754654
6Pustule (HP:0200039)4.73875567
7Rectovaginal fistula (HP:0000143)4.60331618
8Rectal fistula (HP:0100590)4.60331618
9Aplasia/Hypoplasia of the sacrum (HP:0008517)4.49527022
10Increased IgM level (HP:0003496)4.45813856
11Alopecia of scalp (HP:0002293)4.28799682
12Intestinal fistula (HP:0100819)4.07880816
13Turricephaly (HP:0000262)4.05253114
14Poikiloderma (HP:0001029)3.99431641
15Vaginal fistula (HP:0004320)3.97497988
16Tongue fasciculations (HP:0001308)3.90270425
17Male infertility (HP:0003251)3.89906810
18Coronal craniosynostosis (HP:0004440)3.89499314
19Aplasia/Hypoplasia involving the carpal bones (HP:0006502)3.89491551
20Muscle fibrillation (HP:0010546)3.74597746
21Short humerus (HP:0005792)3.69563217
22Thin ribs (HP:0000883)3.66326592
23Ulnar bowing (HP:0003031)3.59170632
24Aplasia/hypoplasia of the humerus (HP:0006507)3.56924118
25Hypoplastic heart (HP:0001961)3.53194536
26Broad distal phalanx of finger (HP:0009836)3.46183113
27Birth length less than 3rd percentile (HP:0003561)3.41755565
28Abnormality of the aortic arch (HP:0012303)3.40495229
29Abnormal hemoglobin (HP:0011902)3.31226479
30Malignant hyperthermia (HP:0002047)3.30679303
31Abnormal ventriculo-arterial connection (HP:0011563)3.30101555
32Transposition of the great arteries (HP:0001669)3.30101555
33Abnormal connection of the cardiac segments (HP:0011545)3.30101555
34Congenital malformation of the right heart (HP:0011723)3.29582849
35Double outlet right ventricle (HP:0001719)3.29582849
36Absent radius (HP:0003974)3.27861299
37Intestinal atresia (HP:0011100)3.24249164
38Orthostatic hypotension (HP:0001278)3.23577768
39Abnormality of male internal genitalia (HP:0000022)3.18098488
40Abnormality of the labia minora (HP:0012880)3.17449017
41Aplasia of the musculature (HP:0100854)3.15617203
42Anteriorly placed anus (HP:0001545)3.15506928
43Absent forearm bone (HP:0003953)3.11083235
44Aplasia involving forearm bones (HP:0009822)3.11083235
45Myopathic facies (HP:0002058)3.10850526
46Popliteal pterygium (HP:0009756)3.10348160
47Alacrima (HP:0000522)3.10182631
48Hypotrichosis (HP:0001006)3.08349761
49Muscle fiber atrophy (HP:0100295)3.05068395
50Septate vagina (HP:0001153)3.03155180
51Congenital hip dislocation (HP:0001374)3.00904786
52Large for gestational age (HP:0001520)3.00417387
53Short chin (HP:0000331)2.98957134
54Breast hypoplasia (HP:0003187)2.97304394
55Type 2 muscle fiber atrophy (HP:0003554)2.97211479
56Hyperthyroidism (HP:0000836)2.96396028
57Premature skin wrinkling (HP:0100678)2.89430002
58Dysautonomia (HP:0002459)2.88673152
59Broad alveolar ridges (HP:0000187)2.88602414
60Testicular atrophy (HP:0000029)2.88497404
61Abnormality of the phalanges of the hallux (HP:0010057)2.87357999
62Vertebral hypoplasia (HP:0008417)2.81316660
63Aplasia/Hypoplasia of the vertebrae (HP:0008515)2.81316660
64Hamartoma (HP:0010566)2.77162923
65Patellar aplasia (HP:0006443)2.76218312
66Gastrointestinal stroma tumor (HP:0100723)2.72917135
67Agammaglobulinemia (HP:0004432)2.71084901
68Bulbar palsy (HP:0001283)2.70936412
69Capillary hemangiomas (HP:0005306)2.70150357
70Abnormality of placental membranes (HP:0011409)2.68856129
71Amniotic constriction ring (HP:0009775)2.68856129
72Emphysema (HP:0002097)2.66766541
73Abnormality of the umbilical cord (HP:0010881)2.66293826
74Volvulus (HP:0002580)2.65296668
75Diaphragmatic weakness (HP:0009113)2.64270841
76Unilateral renal agenesis (HP:0000122)2.64188507
77Squamous cell carcinoma (HP:0002860)2.60575945
78Hypochromic anemia (HP:0001931)2.58828216
79Absent thumb (HP:0009777)2.55939812
80Pancreatic islet-cell hyperplasia (HP:0004510)2.55436279
81Aplasia/Hypoplasia of the patella (HP:0006498)2.54518554
82Distal arthrogryposis (HP:0005684)2.54080680
83Easy fatigability (HP:0003388)2.52880458
84Clumsiness (HP:0002312)2.50598370
85Genu recurvatum (HP:0002816)2.50436662
86Slender long bone (HP:0003100)2.50343977
87Mesangial abnormality (HP:0001966)2.50072776
88Abnormality of the fetal cardiovascular system (HP:0010948)2.48866379
89Abnormal umbilical cord blood vessels (HP:0011403)2.48866379
90Single umbilical artery (HP:0001195)2.48866379
91Round ear (HP:0100830)2.48071033
92Exercise-induced myalgia (HP:0003738)2.47653734
93Decreased lacrimation (HP:0000633)2.46594761
94Truncus arteriosus (HP:0001660)2.45346391
95Bifid uvula (HP:0000193)2.45129924
96Recurrent bacterial skin infections (HP:0005406)2.42159058
97Abnormalities of placenta or umbilical cord (HP:0001194)2.41608874
98Hypertensive crisis (HP:0100735)2.40661298
99Akinesia (HP:0002304)2.39777825
100Hypotelorism (HP:0000601)2.39759781
101Cutaneous melanoma (HP:0012056)2.37663607
102Fetal akinesia sequence (HP:0001989)2.37579868
103Hypokinesia (HP:0002375)2.36972278
104Hemorrhage of the eye (HP:0011885)2.36532096
105Choanal stenosis (HP:0000452)2.34592070
106Delayed epiphyseal ossification (HP:0002663)2.33095160
107Abnormality of chromosome segregation (HP:0002916)2.32911690
108Narrow nasal bridge (HP:0000446)2.32287775
109Abnormality of glycolipid metabolism (HP:0010969)2.31679773
110Abnormality of liposaccharide metabolism (HP:0010968)2.31679773
111Abnormality of glycosphingolipid metabolism (HP:0004343)2.31679773
112Ulnar deviation of the wrist (HP:0003049)2.31167194
113Colitis (HP:0002583)2.30722690
114Urinary glycosaminoglycan excretion (HP:0003541)2.30719854
115Mucopolysacchariduria (HP:0008155)2.30719854
116Asymmetric septal hypertrophy (HP:0001670)2.30462910
117Short middle phalanx of the 5th finger (HP:0004220)2.30364004
118Cellulitis (HP:0100658)2.28726426
119Progressive muscle weakness (HP:0003323)2.28228324
120Germ cell neoplasia (HP:0100728)2.26328652
121Increased number of teeth (HP:0011069)2.25520171
122Shawl scrotum (HP:0000049)2.24109006
123Diminished movement (HP:0002374)2.23365893
124Thin bony cortex (HP:0002753)2.23014438
125Premature graying of hair (HP:0002216)2.21708931
126Growth hormone excess (HP:0000845)2.21152631
127Abnormality of polysaccharide metabolism (HP:0011012)2.20090740
128Abnormality of glycosaminoglycan metabolism (HP:0004371)2.20090740
129Abnormality of mucopolysaccharide metabolism (HP:0011020)2.20090740
130Aplasia/Hypoplasia involving the musculature (HP:0001460)2.19786953
131Polycythemia (HP:0001901)2.17437408
132Albinism (HP:0001022)2.17236639
133Hypoplastic left heart (HP:0004383)2.17093926
134Split hand (HP:0001171)2.16875878
135Median cleft lip (HP:0000161)2.11323616
136Fatigable weakness (HP:0003473)2.09981462
137Abnormality of the neuromuscular junction (HP:0003398)2.09981462
138Hyperacusis (HP:0010780)2.09793614
139Vertebral fusion (HP:0002948)2.09556657
140Stridor (HP:0010307)2.08540626
141Basal cell carcinoma (HP:0002671)2.05770535
142Selective tooth agenesis (HP:0001592)2.04045438
143Joint stiffness (HP:0001387)2.01627028
144Meningitis (HP:0001287)2.01190470
145Acute lymphatic leukemia (HP:0006721)2.00740658
146Atonic seizures (HP:0010819)1.99534085
147Abnormality of the fingertips (HP:0001211)1.98421110
148Abnormal large intestine physiology (HP:0012700)1.96578987
149Bowel incontinence (HP:0002607)1.95714887
150Dysostosis multiplex (HP:0000943)1.94259069
151Redundant skin (HP:0001582)1.94216989
152Flat occiput (HP:0005469)1.93062407
153Cerebral aneurysm (HP:0004944)1.92681677
154Hypoplasia of the radius (HP:0002984)1.92572229
155Hypoplasia of the ulna (HP:0003022)1.92277488
156Purpura (HP:0000979)1.92059033
157Abnormality of the gallbladder (HP:0005264)1.91808092
158Amelogenesis imperfecta (HP:0000705)1.91670493
159Bowing of the arm (HP:0006488)1.88425441
160Bowed forearm bones (HP:0003956)1.88425441
161Gastrointestinal atresia (HP:0002589)1.88213243
162Atrioventricular block (HP:0001678)1.84577395
163Short palpebral fissure (HP:0012745)1.84504099
164Abnormality of the intervertebral disk (HP:0005108)1.82833479
165Recurrent abscess formation (HP:0002722)1.79676919
166Abnormality of the distal phalanges of the toes (HP:0010182)1.78736278
167Absent phalangeal crease (HP:0006109)1.78610024
168Nonimmune hydrops fetalis (HP:0001790)1.77952489
169Chronic obstructive pulmonary disease (HP:0006510)1.77072352
170Obstructive lung disease (HP:0006536)1.77072352
171Abnormality of the thoracic spine (HP:0100711)1.76207250
172Abnormality of the distal phalanx of the thumb (HP:0009617)1.75688374
173Pterygium (HP:0001059)1.74806868
174Symphalangism affecting the phalanges of the hand (HP:0009773)1.72950378
175Vacuolated lymphocytes (HP:0001922)1.71758114
176Abnormality of the tricuspid valve (HP:0001702)1.69949977
177Abnormality of the parathyroid morphology (HP:0011766)1.69764636
178Calcaneovalgus deformity (HP:0001848)1.69470265
179Recurrent skin infections (HP:0001581)1.69143014

Predicted kinase interactions (KEA)

RankGene SetZ-score
1ICK5.78182434
2DDR25.11590867
3MAP3K65.09629647
4MAPK154.57293492
5EEF2K3.92923101
6TRIB33.48996458
7PINK13.45161974
8TYRO33.25653331
9MAP3K113.21349383
10ERN13.19202137
11FGR3.09766935
12MATK2.99414935
13LATS22.41271960
14MAP4K12.34899968
15DAPK12.30387264
16IRAK32.29336032
17MUSK2.22655785
18NME22.17863899
19PRKD22.14854313
20UHMK12.12448588
21BMX2.10099411
22YES12.09080643
23CSK1.99890277
24PIM21.99261879
25CDK41.89697591
26PDGFRA1.87729680
27AKT31.86237417
28SMG11.78368886
29MAP2K31.72135395
30DYRK1B1.72053101
31PHKG11.69217759
32PHKG21.69217759
33CDK71.55081597
34MOS1.48670905
35KDR1.44023596
36LATS11.40320198
37TRPM71.38654475
38BLK1.31928152
39CDK61.30161874
40MAP3K141.28345025
41ARAF1.27316000
42MAP3K131.22061177
43CHEK21.19086555
44IRAK21.18611708
45PRPF4B1.18606721
46PIM11.15713105
47IKBKB1.15475672
48GSK3A1.10886281
49BRD41.10410218
50CDC42BPA1.09624310
51PRKD31.09292275
52RPS6KL11.09125892
53RPS6KC11.09125892
54TAOK21.02426549
55PLK40.99910735
56BRAF0.97512577
57MAP3K10.93777190
58MAPK110.93647408
59RPS6KA60.91658595
60TESK10.89727453
61PLK10.89457995
62PRKAA10.89196987
63CHUK0.87007797
64KSR20.83343894
65SIK10.82044337
66MAP3K80.80536300
67DYRK30.77052687
68PKN20.74417564
69STK40.73858479
70CSNK1G30.73063931
71CAMK1D0.72629800
72MAPK120.71337756
73PDPK10.70907535
74TBK10.70617091
75CDK11A0.68078291
76MAP3K90.67908917
77MTOR0.67599849
78MAP2K20.65727503
79TESK20.64000789
80RPS6KA20.63619691
81CSNK1A1L0.63057430
82STK38L0.62888808
83AKT20.61551454
84MAP3K100.61241505
85RIPK40.60865390
86RAF10.60755328
87HIPK20.60555874
88RPS6KA10.59549652
89STK30.57885467
90CSNK1G10.56378718
91NTRK20.56078995
92CAMK2G0.55357653
93DYRK20.55217843
94IRAK40.54903446
95AURKA0.54624395
96CDK150.54161488
97LMTK20.53239929
98CDK90.52681726
99BCKDK0.50555833
100BRSK10.50469638
101ILK0.50187467
102CDK120.49789111
103CAMK40.49050056
104CDK20.48602730
105STK380.47136091
106RIPK10.46576787
107PDK10.46013177
108CDK180.45287760
109CAMK1G0.44707978
110CSF1R0.44407108
111SIK20.41560055
112CCNB10.41166532
113CAMK2B0.40919364
114CSNK2A10.40072435
115STK110.39885575
116CAMK2A0.39805782
117PAK10.39176952
118MAPK100.38498469
119RPS6KB10.38485087
120PRKAA20.37398048
121FGFR40.36022735
122MELK0.35295441
123CSNK1G20.34440436
124MAPK10.34303802
125ATR0.34071614
126CDK140.33732534
127PDGFRB0.33237852
128MAPK40.33228160
129MAPK30.33021348
130EGFR0.32418614
131BUB10.32129510
132ALK0.29386072
133CHEK10.29259335
134MAPK140.27838110
135ERBB30.27746506
136TTK0.27433039
137CDC70.27114915
138RPS6KB20.27095640
139AURKB0.26179508
140CDK10.26124181
141CSNK2A20.25561603
142ATM0.25315667
143TAOK10.24708098
144TNK20.24337574
145EPHA20.23438106
146PRKCZ0.23420897
147DMPK0.23398169
148RPS6KA30.22370124
149LYN0.22304929
150SGK10.22294181
151CAMK2D0.21827471
152CDK80.21784045
153MARK20.20398318
154PRKD10.19992050
155INSR0.19674093
156GRK50.18356959
157GSK3B0.18038668
158CSNK1E0.16437527
159WEE10.15635810
160NEK10.15401083
161NEK20.14913934
162ERBB40.13701098

Predicted pathways (KEGG)

RankGene SetZ-score
1Fatty acid biosynthesis_Homo sapiens_hsa000615.85730548
2Base excision repair_Homo sapiens_hsa034104.32693997
3Mismatch repair_Homo sapiens_hsa034304.29209283
4B cell receptor signaling pathway_Homo sapiens_hsa046622.91142533
5DNA replication_Homo sapiens_hsa030302.90983348
6Taurine and hypotaurine metabolism_Homo sapiens_hsa004302.86445538
7Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.63314998
8Circadian rhythm_Homo sapiens_hsa047102.62211606
9Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005332.41560679
10Hedgehog signaling pathway_Homo sapiens_hsa043402.41314445
11Other glycan degradation_Homo sapiens_hsa005112.33342848
12mTOR signaling pathway_Homo sapiens_hsa041502.30407802
13Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005322.20451361
14Arginine and proline metabolism_Homo sapiens_hsa003302.12620578
15Hippo signaling pathway_Homo sapiens_hsa043902.10968395
16Nucleotide excision repair_Homo sapiens_hsa034202.07113387
17RNA transport_Homo sapiens_hsa030131.99386309
18Notch signaling pathway_Homo sapiens_hsa043301.89587202
19Allograft rejection_Homo sapiens_hsa053301.81990563
20Non-small cell lung cancer_Homo sapiens_hsa052231.81707864
21Toll-like receptor signaling pathway_Homo sapiens_hsa046201.81049090
22Fanconi anemia pathway_Homo sapiens_hsa034601.76316842
23p53 signaling pathway_Homo sapiens_hsa041151.76280593
24mRNA surveillance pathway_Homo sapiens_hsa030151.75187596
252-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.71340337
26Adherens junction_Homo sapiens_hsa045201.68128070
27Intestinal immune network for IgA production_Homo sapiens_hsa046721.64861324
28Homologous recombination_Homo sapiens_hsa034401.62159288
29Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.60814580
30Longevity regulating pathway - mammal_Homo sapiens_hsa042111.60584823
31Biosynthesis of amino acids_Homo sapiens_hsa012301.58872501
32Spliceosome_Homo sapiens_hsa030401.58801767
33Sulfur relay system_Homo sapiens_hsa041221.58407602
34NF-kappa B signaling pathway_Homo sapiens_hsa040641.51528180
35Cell cycle_Homo sapiens_hsa041101.50484208
36Leishmaniasis_Homo sapiens_hsa051401.48750247
37Fatty acid metabolism_Homo sapiens_hsa012121.47807939
38TGF-beta signaling pathway_Homo sapiens_hsa043501.43137105
39One carbon pool by folate_Homo sapiens_hsa006701.43031745
40HTLV-I infection_Homo sapiens_hsa051661.40104050
41Wnt signaling pathway_Homo sapiens_hsa043101.39148747
42Pancreatic cancer_Homo sapiens_hsa052121.38084338
43Herpes simplex infection_Homo sapiens_hsa051681.36129463
44Autoimmune thyroid disease_Homo sapiens_hsa053201.34872610
45Bladder cancer_Homo sapiens_hsa052191.34036894
46Basal cell carcinoma_Homo sapiens_hsa052171.32158229
47Asthma_Homo sapiens_hsa053101.29182828
48Oocyte meiosis_Homo sapiens_hsa041141.29047709
49Osteoclast differentiation_Homo sapiens_hsa043801.26529420
50Folate biosynthesis_Homo sapiens_hsa007901.25814645
51Tuberculosis_Homo sapiens_hsa051521.24417350
52Graft-versus-host disease_Homo sapiens_hsa053321.22604671
53Dorso-ventral axis formation_Homo sapiens_hsa043201.18733208
54Prion diseases_Homo sapiens_hsa050201.13768845
55Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.13632779
56Lysosome_Homo sapiens_hsa041421.12309406
57Glioma_Homo sapiens_hsa052141.12175397
58Neurotrophin signaling pathway_Homo sapiens_hsa047221.11891569
59Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.09277043
60Transcriptional misregulation in cancer_Homo sapiens_hsa052021.09138603
61Hepatitis B_Homo sapiens_hsa051611.06813959
62Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.06433500
63Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.06014949
64RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.02840709
65Influenza A_Homo sapiens_hsa051641.02739470
66Lysine degradation_Homo sapiens_hsa003101.00068674
67Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.95588814
68Vitamin B6 metabolism_Homo sapiens_hsa007500.95356726
69VEGF signaling pathway_Homo sapiens_hsa043700.94447731
70Type I diabetes mellitus_Homo sapiens_hsa049400.92044773
71Pentose and glucuronate interconversions_Homo sapiens_hsa000400.91195423
72Tight junction_Homo sapiens_hsa045300.90074664
73Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.89918854
74Choline metabolism in cancer_Homo sapiens_hsa052310.84691642
75African trypanosomiasis_Homo sapiens_hsa051430.84601376
76Toxoplasmosis_Homo sapiens_hsa051450.84139779
77Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.81992171
78Apoptosis_Homo sapiens_hsa042100.80681919
79TNF signaling pathway_Homo sapiens_hsa046680.79313660
80RNA polymerase_Homo sapiens_hsa030200.79006249
81Fructose and mannose metabolism_Homo sapiens_hsa000510.77988360
82Rheumatoid arthritis_Homo sapiens_hsa053230.76959646
83ErbB signaling pathway_Homo sapiens_hsa040120.76923629
84T cell receptor signaling pathway_Homo sapiens_hsa046600.76337132
85Malaria_Homo sapiens_hsa051440.76229772
86Maturity onset diabetes of the young_Homo sapiens_hsa049500.75540372
87Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.74128628
88Arginine biosynthesis_Homo sapiens_hsa002200.73445488
89Regulation of actin cytoskeleton_Homo sapiens_hsa048100.73381489
90Gap junction_Homo sapiens_hsa045400.72072431
91MicroRNAs in cancer_Homo sapiens_hsa052060.71655234
92Staphylococcus aureus infection_Homo sapiens_hsa051500.70629553
93Antigen processing and presentation_Homo sapiens_hsa046120.69427706
94Systemic lupus erythematosus_Homo sapiens_hsa053220.68692807
95Shigellosis_Homo sapiens_hsa051310.68032813
96Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.67549997
97Salmonella infection_Homo sapiens_hsa051320.66322033
98AMPK signaling pathway_Homo sapiens_hsa041520.65877348
99Colorectal cancer_Homo sapiens_hsa052100.65138133
100Glycosaminoglycan degradation_Homo sapiens_hsa005310.64900609
101Adipocytokine signaling pathway_Homo sapiens_hsa049200.63695804
102Insulin signaling pathway_Homo sapiens_hsa049100.58996294
103Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.58737430
104Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.55164085
105Basal transcription factors_Homo sapiens_hsa030220.51992396
106Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.50903719
107AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.50211322
108Thyroid cancer_Homo sapiens_hsa052160.48781858
109Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.48672205
110Measles_Homo sapiens_hsa051620.47904532
111HIF-1 signaling pathway_Homo sapiens_hsa040660.46345690
112Viral myocarditis_Homo sapiens_hsa054160.45458195
113Ribosome_Homo sapiens_hsa030100.44409060
114Sphingolipid signaling pathway_Homo sapiens_hsa040710.44292929
115Jak-STAT signaling pathway_Homo sapiens_hsa046300.44242372
116MAPK signaling pathway_Homo sapiens_hsa040100.43311733
117FoxO signaling pathway_Homo sapiens_hsa040680.43050974
118GnRH signaling pathway_Homo sapiens_hsa049120.42750941
119Legionellosis_Homo sapiens_hsa051340.42737386
120Pertussis_Homo sapiens_hsa051330.42561152
121Linoleic acid metabolism_Homo sapiens_hsa005910.41845356
122Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.38636108
123Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.38311809
124Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.37213478
125RNA degradation_Homo sapiens_hsa030180.36917147
126Glutathione metabolism_Homo sapiens_hsa004800.35331925
127Steroid biosynthesis_Homo sapiens_hsa001000.34122330
128alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.33490466
129Proteoglycans in cancer_Homo sapiens_hsa052050.31316364
130Small cell lung cancer_Homo sapiens_hsa052220.31041454
131Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.30293230
132Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.30030800
133Galactose metabolism_Homo sapiens_hsa000520.29218497
134Long-term depression_Homo sapiens_hsa047300.28584772
135Endometrial cancer_Homo sapiens_hsa052130.27493569
136Primary immunodeficiency_Homo sapiens_hsa053400.27474261
137Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.27123142
138Acute myeloid leukemia_Homo sapiens_hsa052210.26873032
139Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.26082179
140Glycerophospholipid metabolism_Homo sapiens_hsa005640.25067202
141PI3K-Akt signaling pathway_Homo sapiens_hsa041510.20425079
142Viral carcinogenesis_Homo sapiens_hsa052030.20280942
143Estrogen signaling pathway_Homo sapiens_hsa049150.19841021
144Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.18473999
145Chronic myeloid leukemia_Homo sapiens_hsa052200.18301004
146Epstein-Barr virus infection_Homo sapiens_hsa051690.18121891
147Cysteine and methionine metabolism_Homo sapiens_hsa002700.17965347
148Pathways in cancer_Homo sapiens_hsa052000.16025424
149Thyroid hormone signaling pathway_Homo sapiens_hsa049190.15952978
150Prostate cancer_Homo sapiens_hsa052150.15949734
151Proteasome_Homo sapiens_hsa030500.15331150
152Melanoma_Homo sapiens_hsa052180.15163903
153Cyanoamino acid metabolism_Homo sapiens_hsa004600.13333127
154Focal adhesion_Homo sapiens_hsa045100.12194395
155Arachidonic acid metabolism_Homo sapiens_hsa005900.12157750
156Mineral absorption_Homo sapiens_hsa049780.12033672

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »