UXT

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: The protein encoded by this gene functions as a cofactor that modulates androgen receptor-dependent transcription, and also plays a critical role in tumor necrosis factor-induced apoptosis. Expression of this gene may play a role in tumorigenesis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1ribosomal small subunit assembly (GO:0000028)5.78035464
2viral transcription (GO:0019083)5.18349237
3translational termination (GO:0006415)5.04605122
4ribosomal small subunit biogenesis (GO:0042274)5.01140207
5mitochondrial electron transport, NADH to ubiquinone (GO:0006120)5.01024261
6respiratory electron transport chain (GO:0022904)4.95706152
7electron transport chain (GO:0022900)4.86906247
8DNA deamination (GO:0045006)4.79942558
9SRP-dependent cotranslational protein targeting to membrane (GO:0006614)4.75900418
10proteasome assembly (GO:0043248)4.75583431
11protein complex biogenesis (GO:0070271)4.72586663
12maturation of SSU-rRNA (GO:0030490)4.72251637
13cotranslational protein targeting to membrane (GO:0006613)4.67619375
14protein targeting to ER (GO:0045047)4.64909775
15ribosomal large subunit biogenesis (GO:0042273)4.52430501
16translational elongation (GO:0006414)4.46319581
17protein localization to endoplasmic reticulum (GO:0070972)4.43670658
18chaperone-mediated protein transport (GO:0072321)4.42622141
19establishment of protein localization to endoplasmic reticulum (GO:0072599)4.41104944
20establishment of protein localization to mitochondrial membrane (GO:0090151)4.32829714
21mitochondrial respiratory chain complex assembly (GO:0033108)4.32216638
22mitochondrial respiratory chain complex I assembly (GO:0032981)4.24273897
23NADH dehydrogenase complex assembly (GO:0010257)4.24273897
24mitochondrial respiratory chain complex I biogenesis (GO:0097031)4.24273897
25protein neddylation (GO:0045116)4.15970342
26translational initiation (GO:0006413)4.12516254
27telomere maintenance via semi-conservative replication (GO:0032201)4.06852675
28viral life cycle (GO:0019058)3.98463483
29respiratory chain complex IV assembly (GO:0008535)3.97149958
30DNA strand elongation involved in DNA replication (GO:0006271)3.93809559
31cytochrome complex assembly (GO:0017004)3.92479405
32ribonucleoprotein complex biogenesis (GO:0022613)3.91302012
33cellular protein complex disassembly (GO:0043624)3.88644981
34nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.87982993
35termination of RNA polymerase III transcription (GO:0006386)3.86409573
36transcription elongation from RNA polymerase III promoter (GO:0006385)3.86409573
37translation (GO:0006412)3.86140577
38negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.77334202
39telomere maintenance via recombination (GO:0000722)3.75396307
40pyrimidine deoxyribonucleotide catabolic process (GO:0009223)3.74723756
41DNA strand elongation (GO:0022616)3.73685787
42formation of translation preinitiation complex (GO:0001731)3.69482370
43protein targeting to mitochondrion (GO:0006626)3.65230233
44DNA replication checkpoint (GO:0000076)3.61540610
45deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.58563536
46ATP biosynthetic process (GO:0006754)3.55154660
47purine ribonucleoside triphosphate biosynthetic process (GO:0009206)3.53434823
48purine nucleoside triphosphate biosynthetic process (GO:0009145)3.53219988
49positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.52646719
50regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.52301695
51GTP biosynthetic process (GO:0006183)3.47988674
52antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:3.46722404
53purine nucleobase biosynthetic process (GO:0009113)3.44452822
54DNA replication initiation (GO:0006270)3.43841500
55establishment of protein localization to mitochondrion (GO:0072655)3.43796825
56rRNA modification (GO:0000154)3.42644075
57negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.42635409
58negative regulation of ligase activity (GO:0051352)3.42635409
59peptidyl-histidine modification (GO:0018202)3.42545809
60L-methionine biosynthetic process from methylthioadenosine (GO:0019509)3.41991813
61anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.40843990
62rRNA processing (GO:0006364)3.40809218
63nucleobase biosynthetic process (GO:0046112)3.38335140
64mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.36993063
65regulation of cellular amino acid metabolic process (GO:0006521)3.36809096
66DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:003.34342155
67cellular component biogenesis (GO:0044085)3.33857662
68CENP-A containing nucleosome assembly (GO:0034080)3.33805372
69protein complex disassembly (GO:0043241)3.32808705
70mitotic recombination (GO:0006312)3.32741130
71spliceosomal snRNP assembly (GO:0000387)3.32166162
72pseudouridine synthesis (GO:0001522)3.31926050
73antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590)3.31577703
74ribosome biogenesis (GO:0042254)3.31203167
75intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)3.28645897
76signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)3.28645897
77protein localization to mitochondrion (GO:0070585)3.27801062
78signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)3.27679896
79signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)3.27679896
80signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)3.27679896
81RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.26967544
82tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.26967544
83rRNA metabolic process (GO:0016072)3.26384771
84cullin deneddylation (GO:0010388)3.24247756
85transcription-coupled nucleotide-excision repair (GO:0006283)3.22760018
86chromatin remodeling at centromere (GO:0031055)3.22508436
87signal transduction involved in DNA damage checkpoint (GO:0072422)3.20455349
88signal transduction involved in DNA integrity checkpoint (GO:0072401)3.20455349
89guanosine-containing compound biosynthetic process (GO:1901070)3.19952823
907-methylguanosine mRNA capping (GO:0006370)3.19904723
91macromolecular complex disassembly (GO:0032984)3.19654964
92protein deneddylation (GO:0000338)3.19260994
93ribonucleoside triphosphate biosynthetic process (GO:0009201)3.18513360
94signal transduction involved in cell cycle checkpoint (GO:0072395)3.15565210
95hydrogen ion transmembrane transport (GO:1902600)3.14592348
967-methylguanosine RNA capping (GO:0009452)3.14488345
97RNA capping (GO:0036260)3.14488345
98ATP synthesis coupled proton transport (GO:0015986)3.12903323
99energy coupled proton transport, down electrochemical gradient (GO:0015985)3.12903323
100deoxyribonucleoside triphosphate metabolic process (GO:0009200)3.10809836
101positive regulation of ubiquitin-protein transferase activity (GO:0051443)3.10429232
102deoxyribonucleotide catabolic process (GO:0009264)3.09438299
103UTP biosynthetic process (GO:0006228)3.06544291
104pyrimidine nucleotide catabolic process (GO:0006244)3.05426493
105regulation of mitochondrial translation (GO:0070129)3.04420604
106nuclear-transcribed mRNA catabolic process (GO:0000956)3.04174613
107amino acid salvage (GO:0043102)3.03949632
108L-methionine salvage (GO:0071267)3.03949632
109L-methionine biosynthetic process (GO:0071265)3.03949632
110nucleotide-excision repair, DNA gap filling (GO:0006297)3.01886712
111positive regulation of ligase activity (GO:0051351)3.01453810
112telomere maintenance via telomere lengthening (GO:0010833)3.00814028
113exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 2.99951082
114protein targeting to membrane (GO:0006612)2.99442669
115deoxyribonucleotide biosynthetic process (GO:0009263)2.99102265
116deoxyribose phosphate catabolic process (GO:0046386)2.98934660
1172-deoxyribonucleotide biosynthetic process (GO:0009265)2.98189417
118deoxyribose phosphate biosynthetic process (GO:0046385)2.98189417
119nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)2.96494943
120mitochondrial transport (GO:0006839)2.93640037
121protein maturation by protein folding (GO:0022417)2.91723043
122oxidative phosphorylation (GO:0006119)2.91524241
123mRNA catabolic process (GO:0006402)2.89603502
124response to interferon-beta (GO:0035456)2.89444529
125purine deoxyribonucleoside triphosphate metabolic process (GO:0009215)2.89419437
126spliceosomal complex assembly (GO:0000245)2.89133619
127mitotic metaphase plate congression (GO:0007080)2.87426734
128nucleoside triphosphate biosynthetic process (GO:0009142)2.86512698
129nucleobase-containing small molecule interconversion (GO:0015949)2.86391987
130purine nucleotide salvage (GO:0032261)2.85681010
131cellular response to interferon-beta (GO:0035458)2.84546587
132ribosome assembly (GO:0042255)2.84405097
133protein targeting (GO:0006605)2.83984457
134G1/S transition of mitotic cell cycle (GO:0000082)2.81449623
135cell cycle G1/S phase transition (GO:0044843)2.81449623
136antigen processing and presentation of peptide antigen via MHC class I (GO:0002474)2.79184336
137pyrimidine deoxyribonucleotide metabolic process (GO:0009219)2.78204547
138termination of RNA polymerase I transcription (GO:0006363)2.78038850
139RNA catabolic process (GO:0006401)2.76347753

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human5.74973768
2KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human4.19943343
3MYC_18555785_ChIP-Seq_MESCs_Mouse4.06017818
4GABP_17652178_ChIP-ChIP_JURKAT_Human3.76393740
5EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.64779363
6EST1_17652178_ChIP-ChIP_JURKAT_Human3.62401061
7* JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.50961988
8* CREB1_15753290_ChIP-ChIP_HEK293T_Human3.24204724
9ETS1_20019798_ChIP-Seq_JURKAT_Human3.21300218
10SOX9_22984422_ChIP-ChIP_TESTIS_Rat3.10676178
11NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.92293066
12MYC_18358816_ChIP-ChIP_MESCs_Mouse2.91636180
13ELF1_17652178_ChIP-ChIP_JURKAT_Human2.79816634
14E2F4_17652178_ChIP-ChIP_JURKAT_Human2.71281504
15MYC_19030024_ChIP-ChIP_MESCs_Mouse2.69420992
16MYC_19079543_ChIP-ChIP_MESCs_Mouse2.68048318
17CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.67539580
18VDR_23849224_ChIP-Seq_CD4+_Human2.53822823
19HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.53395490
20FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.47350142
21CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.42899587
22E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.37795723
23HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.37002769
24DCP1A_22483619_ChIP-Seq_HELA_Human2.34184116
25* E2F1_18555785_ChIP-Seq_MESCs_Mouse2.24381018
26FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.24089413
27XRN2_22483619_ChIP-Seq_HELA_Human2.23789579
28TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat2.17577114
29NELFA_20434984_ChIP-Seq_ESCs_Mouse2.15937448
30SRF_21415370_ChIP-Seq_HL-1_Mouse2.10822432
31FOXP3_21729870_ChIP-Seq_TREG_Human2.10769585
32SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.07670688
33FOXM1_23109430_ChIP-Seq_U2OS_Human2.02909474
34ELK1_19687146_ChIP-ChIP_HELA_Human1.98810832
35GABP_19822575_ChIP-Seq_HepG2_Human1.90427198
36FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.86022297
37* PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.83220735
38TTF2_22483619_ChIP-Seq_HELA_Human1.81213797
39BP1_19119308_ChIP-ChIP_Hs578T_Human1.80405910
40* HOXB4_20404135_ChIP-ChIP_EML_Mouse1.79254263
41THAP11_20581084_ChIP-Seq_MESCs_Mouse1.74855459
42TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.69319472
43YY1_21170310_ChIP-Seq_MESCs_Mouse1.67930039
44FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.67903062
45PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.67745597
46MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.60488221
47CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.54865027
48MYCN_18555785_ChIP-Seq_MESCs_Mouse1.54563781
49MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.52131082
50NANOG_18555785_ChIP-Seq_MESCs_Mouse1.52066454
51ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.49541477
52ERG_20887958_ChIP-Seq_HPC-7_Mouse1.48583788
53POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.46182612
54AR_21909140_ChIP-Seq_LNCAP_Human1.43842773
55SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.43651891
56IRF8_22096565_ChIP-ChIP_GC-B_Human1.40124503
57CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.39596958
58IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.38342149
59CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.37965015
60ZFX_18555785_ChIP-Seq_MESCs_Mouse1.35910172
61SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.35891576
62E2F1_21310950_ChIP-Seq_MCF-7_Human1.34734888
63ELK1_22589737_ChIP-Seq_MCF10A_Human1.27837825
64YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.27593505
65KDM5A_27292631_Chip-Seq_BREAST_Human1.21507937
66SPI1_23547873_ChIP-Seq_NB4_Human1.19868769
67BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.17748135
68MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.17524246
69* PADI4_21655091_ChIP-ChIP_MCF-7_Human1.15132001
70CTCF_18555785_ChIP-Seq_MESCs_Mouse1.14624939
71NOTCH1_21737748_ChIP-Seq_TLL_Human1.13078311
72TFEB_21752829_ChIP-Seq_HELA_Human1.13035357
73CIITA_25753668_ChIP-Seq_RAJI_Human1.11905891
74TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.10114146
75* ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.08229232
76BCL6_27268052_Chip-Seq_Bcells_Human1.07985451
77MYC_18940864_ChIP-ChIP_HL60_Human1.07444310
78ELF1_20517297_ChIP-Seq_JURKAT_Human1.07237266
79* CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human1.06842057
80ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.06775878
81POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.06669096
82HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.05907280
83RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.04242796
84CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.04213784
85E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.01091213
86PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse1.00973682
87HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.00604199
88EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.00442394
89EGR1_23403033_ChIP-Seq_LIVER_Mouse0.99044282
90CTCF_26484167_Chip-Seq_Bcells_Mouse0.97966400
91IRF8_21731497_ChIP-ChIP_J774_Mouse0.97240205
92STAT3_1855785_ChIP-Seq_MESCs_Mouse0.96220784
93RBPJ_21746931_ChIP-Seq_IB4-LCL_Human0.95207485
94PPARG_19300518_ChIP-PET_3T3-L1_Mouse0.94615218
95GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.93104809
96VDR_21846776_ChIP-Seq_THP-1_Human0.92356444
97FOXP1_21924763_ChIP-Seq_HESCs_Human0.92027969
98KLF4_18555785_ChIP-Seq_MESCs_Mouse0.90063086
99LYL1_20887958_ChIP-Seq_HPC-7_Mouse0.89545880
100MYB_26560356_Chip-Seq_TH2_Human0.89545170
101YY1_22570637_ChIP-Seq_MALME-3M_Human0.89275275
102* KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.89090945
103CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.88334483
104SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.88019091
105STAT1_20625510_ChIP-Seq_HELA_Human0.87640382
106MAF_26560356_Chip-Seq_TH2_Human0.86181881
107MEIS1_20887958_ChIP-Seq_HPC-7_Mouse0.85417944
108SRY_22984422_ChIP-ChIP_TESTIS_Rat0.85096189
109SOX17_20123909_ChIP-Seq_XEN_Mouse0.82740868
110* STAT4_19710469_ChIP-ChIP_TH1__Mouse0.82409243
111HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.82265939
112POU5F1_18700969_ChIP-ChIP_MESCs_Mouse0.81067459
113GATA1_22025678_ChIP-Seq_K562_Human0.79895436
114FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.77427556
115ESR1_17901129_ChIP-ChIP_LIVER_Mouse0.73349279
116GATA1_22383799_ChIP-Seq_G1ME_Mouse0.72917471
117SOX2_18555785_ChIP-Seq_MESCs_Mouse0.72900383
118TBX5_21415370_ChIP-Seq_HL-1_Mouse0.72252332
119DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.72227560
120SOX2_18692474_ChIP-Seq_MEFs_Mouse0.70598838
121DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.70245342
122MECOM_23826213_ChIP-Seq_KASUMI_Mouse0.68775924

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching4.82005474
2MP0004957_abnormal_blastocyst_morpholog3.59318619
3MP0003806_abnormal_nucleotide_metabolis3.30235307
4MP0008057_abnormal_DNA_replication3.18523591
5MP0010094_abnormal_chromosome_stability3.11922734
6MP0003077_abnormal_cell_cycle2.95350159
7MP0003111_abnormal_nucleus_morphology2.94444963
8MP0003186_abnormal_redox_activity2.83329863
9MP0009379_abnormal_foot_pigmentation2.71756679
10MP0008058_abnormal_DNA_repair2.68649213
11MP0008007_abnormal_cellular_replicative2.32204157
12MP0008932_abnormal_embryonic_tissue2.28743044
13MP0003718_maternal_effect2.13777397
14MP0006036_abnormal_mitochondrial_physio2.05501507
15MP0002837_dystrophic_cardiac_calcinosis1.97234041
16MP0003786_premature_aging1.89309538
17MP0009333_abnormal_splenocyte_physiolog1.87565236
18MP0002163_abnormal_gland_morphology1.84246435
19MP0001835_abnormal_antigen_presentation1.77930890
20MP0008995_early_reproductive_senescence1.77209333
21MP0002396_abnormal_hematopoietic_system1.75865359
22MP0001873_stomach_inflammation1.74318037
23MP0009785_altered_susceptibility_to1.68814750
24MP0003656_abnormal_erythrocyte_physiolo1.65724492
25MP0002148_abnormal_hypersensitivity_rea1.60453502
26MP0005671_abnormal_response_to1.52309216
27MP0001853_heart_inflammation1.52205898
28MP0002132_abnormal_respiratory_system1.49663437
29MP0005464_abnormal_platelet_physiology1.49553579
30MP0005379_endocrine/exocrine_gland_phen1.44246829
31MP0006035_abnormal_mitochondrial_morpho1.44070219
32MP0009764_decreased_sensitivity_to1.42300059
33MP0003436_decreased_susceptibility_to1.39570686
34MP0000490_abnormal_crypts_of1.39212770
35MP0002277_abnormal_respiratory_mucosa1.38442468
36MP0002139_abnormal_hepatobiliary_system1.36604290
37MP0001730_embryonic_growth_arrest1.36407608
38MP0005025_abnormal_response_to1.34020193
39MP0003763_abnormal_thymus_physiology1.33924320
40MP0001764_abnormal_homeostasis1.33263415
41MP0000343_altered_response_to1.30697258
42MP0000350_abnormal_cell_proliferation1.26412623
43MP0005084_abnormal_gallbladder_morpholo1.23856772
44MP0005451_abnormal_body_composition1.23690658
45MP0001905_abnormal_dopamine_level1.23131766
46MP0002019_abnormal_tumor_incidence1.21328675
47MP0003724_increased_susceptibility_to1.20852013
48MP0005075_abnormal_melanosome_morpholog1.20095796
49MP0005000_abnormal_immune_tolerance1.19754590
50MP0005397_hematopoietic_system_phenotyp1.19427779
51MP0001545_abnormal_hematopoietic_system1.19427779
52MP0000313_abnormal_cell_death1.18903755
53MP0002138_abnormal_hepatobiliary_system1.18327802
54MP0002398_abnormal_bone_marrow1.16393724
55MP0000689_abnormal_spleen_morphology1.13716181
56MP0004142_abnormal_muscle_tone1.11970554
57MP0001529_abnormal_vocalization1.11272785
58MP0003195_calcinosis1.10640712
59MP0004147_increased_porphyrin_level1.10362087
60MP0002722_abnormal_immune_system1.10200678
61MP0002723_abnormal_immune_serum1.10099546
62MP0002095_abnormal_skin_pigmentation1.09934775
63MP0000685_abnormal_immune_system1.09784259
64MP0001800_abnormal_humoral_immune1.08260743
65MP0000372_irregular_coat_pigmentation1.08137363
66MP0002452_abnormal_antigen_presenting1.06859292
67MP0002429_abnormal_blood_cell1.06303799
68MP0006054_spinal_hemorrhage1.05546322
69MP0005646_abnormal_pituitary_gland1.04512053
70MP0009840_abnormal_foam_cell1.04437183
71MP0009697_abnormal_copulation1.04010582
72MP0002420_abnormal_adaptive_immunity1.03954823
73MP0001819_abnormal_immune_cell1.03767201
74MP0002419_abnormal_innate_immunity1.02488557
75MP0008469_abnormal_protein_level1.02448547
76MP0000716_abnormal_immune_system1.02397241
77MP0003123_paternal_imprinting1.02291728
78MP0010352_gastrointestinal_tract_polyps1.00829059
79MP0005389_reproductive_system_phenotype1.00150836
80MP0006292_abnormal_olfactory_placode0.99435859
81MP0008875_abnormal_xenobiotic_pharmacok0.98192237
82MP0006072_abnormal_retinal_apoptosis0.97541035
83MP0002693_abnormal_pancreas_physiology0.97276452
84MP0005410_abnormal_fertilization0.93740221
85MP0006082_CNS_inflammation0.92333816
86MP0005645_abnormal_hypothalamus_physiol0.91205076
87MP0005083_abnormal_biliary_tract0.90903584
88MP0000858_altered_metastatic_potential0.90879683
89MP0005408_hypopigmentation0.90532348
90MP0002405_respiratory_system_inflammati0.89818143
91MP0001919_abnormal_reproductive_system0.89567200
92MP0000358_abnormal_cell_content/0.89184248
93MP0002080_prenatal_lethality0.88352561
94MP0005365_abnormal_bile_salt0.87586440
95MP0001697_abnormal_embryo_size0.87272866
96MP0003011_delayed_dark_adaptation0.87037468
97MP0008872_abnormal_physiological_respon0.86360175
98MP0005319_abnormal_enzyme/_coenzyme0.83845844
99MP0009765_abnormal_xenobiotic_induced0.83719421
100MP0003303_peritoneal_inflammation0.82985199
101MP0001845_abnormal_inflammatory_respons0.82455005
102MP0005332_abnormal_amino_acid0.82175379
103MP0002653_abnormal_ependyma_morphology0.82015712
104MP0005387_immune_system_phenotype0.81797820
105MP0001790_abnormal_immune_system0.81797820
106MP0008789_abnormal_olfactory_epithelium0.81641798
107MP0003866_abnormal_defecation0.81242287
108MP0005085_abnormal_gallbladder_physiolo0.80117954
109MP0003646_muscle_fatigue0.79209516
110MP0005380_embryogenesis_phenotype0.78898676
111MP0001672_abnormal_embryogenesis/_devel0.78898676
112MP0005266_abnormal_metabolism0.78733500
113MP0000015_abnormal_ear_pigmentation0.78584630
114MP0004019_abnormal_vitamin_homeostasis0.78425183
115MP0002876_abnormal_thyroid_physiology0.78348882
116MP0010155_abnormal_intestine_physiology0.77423448
117MP0003136_yellow_coat_color0.77239896
118MP0001986_abnormal_taste_sensitivity0.77186463
119MP0005636_abnormal_mineral_homeostasis0.77004452
120MP0004808_abnormal_hematopoietic_stem0.75971429
121MP0002160_abnormal_reproductive_system0.75442695
122MP0001542_abnormal_bone_strength0.75343094
123MP0002210_abnormal_sex_determination0.74626040
124MP0003984_embryonic_growth_retardation0.74244001
125MP0000703_abnormal_thymus_morphology0.74106966
126MP0002938_white_spotting0.73502355
127MP0005360_urolithiasis0.72786913
128MP0002088_abnormal_embryonic_growth/wei0.72388485
129MP0003315_abnormal_perineum_morphology0.71160922
130MP0008877_abnormal_DNA_methylation0.67733357
131MP0002933_joint_inflammation0.67687050
132MP0000598_abnormal_liver_morphology0.67523349
133MP0002006_tumorigenesis0.67517913
134MP0009763_increased_sensitivity_to0.66556259

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of cells of the erythroid lineage (HP:0012130)5.18279347
2Abnormal number of erythroid precursors (HP:0012131)5.08348371
3Reticulocytopenia (HP:0001896)4.76264525
4Macrocytic anemia (HP:0001972)3.90008344
5Acute necrotizing encephalopathy (HP:0006965)3.79116326
6Hepatic necrosis (HP:0002605)3.71652780
7Mitochondrial inheritance (HP:0001427)3.69379293
8Hepatocellular necrosis (HP:0001404)3.57273916
93-Methylglutaconic aciduria (HP:0003535)3.56385769
10Birth length less than 3rd percentile (HP:0003561)3.54483527
11Abnormal mitochondria in muscle tissue (HP:0008316)3.49796816
12Increased CSF lactate (HP:0002490)3.42327158
13Increased hepatocellular lipid droplets (HP:0006565)3.37578773
14Pallor (HP:0000980)3.34190599
15Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)3.34018591
16Abnormal activity of mitochondrial respiratory chain (HP:0011922)3.33357213
17Decreased activity of mitochondrial respiratory chain (HP:0008972)3.33357213
18Breast hypoplasia (HP:0003187)3.25255661
19Increased serum lactate (HP:0002151)3.25215571
20Lipid accumulation in hepatocytes (HP:0006561)3.25108361
21Acute encephalopathy (HP:0006846)3.24489927
22Abnormality of glycolysis (HP:0004366)3.18402448
23Increased serum pyruvate (HP:0003542)3.18402448
24Aplastic anemia (HP:0001915)3.17300830
25Aplasia/Hypoplasia of the sacrum (HP:0008517)3.07616680
26Progressive macrocephaly (HP:0004481)3.02634442
27Muscle abnormality related to mitochondrial dysfunction (HP:0003800)3.01377516
28Exertional dyspnea (HP:0002875)2.98502152
29Rough bone trabeculation (HP:0100670)2.96138935
30Oral leukoplakia (HP:0002745)2.92263254
31Optic disc pallor (HP:0000543)2.80687022
32Absent rod-and cone-mediated responses on ERG (HP:0007688)2.79802971
33Multiple enchondromatosis (HP:0005701)2.79355168
34Type I transferrin isoform profile (HP:0003642)2.74278571
35Cerebral hypomyelination (HP:0006808)2.69553086
36Stomatitis (HP:0010280)2.69315776
37Microretrognathia (HP:0000308)2.65649143
38Renal Fanconi syndrome (HP:0001994)2.64427593
39Cerebral edema (HP:0002181)2.64039080
40Lactic acidosis (HP:0003128)2.63355374
41Abnormality of renal resorption (HP:0011038)2.57687575
42Increased intramyocellular lipid droplets (HP:0012240)2.54611268
43Exercise intolerance (HP:0003546)2.47358510
44Respiratory failure (HP:0002878)2.46237891
45Nausea (HP:0002018)2.43935915
46Emotional lability (HP:0000712)2.42443864
47Abnormal trabecular bone morphology (HP:0100671)2.41553049
48Carpal bone hypoplasia (HP:0001498)2.40925386
49Microvesicular hepatic steatosis (HP:0001414)2.40685162
50Increased muscle lipid content (HP:0009058)2.33790009
51Generalized aminoaciduria (HP:0002909)2.33326490
52Poor head control (HP:0002421)2.29835509
53Chromsome breakage (HP:0040012)2.27716785
54Reduced antithrombin III activity (HP:0001976)2.27023828
55Abnormal hemoglobin (HP:0011902)2.26027737
56Absent thumb (HP:0009777)2.24714766
57Chromosomal breakage induced by crosslinking agents (HP:0003221)2.23521017
58Pancytopenia (HP:0001876)2.21665561
59Abnormal rod and cone electroretinograms (HP:0008323)2.18875730
60Megaloblastic anemia (HP:0001889)2.10585286
61CNS demyelination (HP:0007305)2.10484807
62Secondary amenorrhea (HP:0000869)2.10479718
63Progressive muscle weakness (HP:0003323)2.10220825
64Sparse eyelashes (HP:0000653)2.10105168
65Abnormality of dicarboxylic acid metabolism (HP:0010995)2.09882519
66Dicarboxylic aciduria (HP:0003215)2.09882519
67Abnormality of the heme biosynthetic pathway (HP:0010472)2.09856784
68Respiratory difficulties (HP:0002880)2.08585294
69Abnormality of the preputium (HP:0100587)2.08046999
70Hyperphosphaturia (HP:0003109)2.06976763
71Lethargy (HP:0001254)2.04332988
72Abnormality of pyrimidine metabolism (HP:0004353)2.04238343
73Muscle fiber atrophy (HP:0100295)2.03583736
74X-linked dominant inheritance (HP:0001423)2.02387114
75Abnormal protein glycosylation (HP:0012346)2.02129369
76Abnormal glycosylation (HP:0012345)2.02129369
77Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.02129369
78Abnormal protein N-linked glycosylation (HP:0012347)2.02129369
79Increased IgM level (HP:0003496)2.01262300
80Abnormality of T cell physiology (HP:0011840)2.01091359
81Trismus (HP:0000211)2.00770705
82Thrombocytosis (HP:0001894)2.00667610
83Type 2 muscle fiber atrophy (HP:0003554)2.00174212
84IgM deficiency (HP:0002850)1.98639662
85Irregular epiphyses (HP:0010582)1.97735836
86Glycosuria (HP:0003076)1.97122870
87Abnormality of urine glucose concentration (HP:0011016)1.97122870
88Premature graying of hair (HP:0002216)1.95797639
89Bone marrow hypocellularity (HP:0005528)1.95737747
90Prolonged neonatal jaundice (HP:0006579)1.95102467
91Parakeratosis (HP:0001036)1.94825223
92IgG deficiency (HP:0004315)1.93451489
93Abnormality of reticulocytes (HP:0004312)1.90161914
94Elevated erythrocyte sedimentation rate (HP:0003565)1.87291000
95Abnormality of serum amino acid levels (HP:0003112)1.86501536
96Patellar aplasia (HP:0006443)1.86294769
97Meckel diverticulum (HP:0002245)1.86256412
98Petechiae (HP:0000967)1.85391161
99Leukodystrophy (HP:0002415)1.84156936
100Colon cancer (HP:0003003)1.82751349
101Duplicated collecting system (HP:0000081)1.81838043
102Abnormality of aromatic amino acid family metabolism (HP:0004338)1.81364698
103Congenital nonbullous ichthyosiform erythroderma (HP:0007479)1.80919687
10411 pairs of ribs (HP:0000878)1.80527745
105B lymphocytopenia (HP:0010976)1.79933542
106Cleft eyelid (HP:0000625)1.78263300
107Abnormality of the renal collecting system (HP:0004742)1.78159900
108Congenital, generalized hypertrichosis (HP:0004540)1.77937242
109Abnormality of the ileum (HP:0001549)1.76550213
110Degeneration of anterior horn cells (HP:0002398)1.75966228
111Abnormality of the anterior horn cell (HP:0006802)1.75966228
112Aplasia/Hypoplasia of the patella (HP:0006498)1.74702658
113Neutropenia (HP:0001875)1.74044591
114Aplasia/hypoplasia of the uterus (HP:0008684)1.73237885
115Methylmalonic aciduria (HP:0012120)1.72439852
116Triphalangeal thumb (HP:0001199)1.71860825
117Cerebral palsy (HP:0100021)1.69689009
118Blindness (HP:0000618)1.69107441
119Panhypogammaglobulinemia (HP:0003139)1.68815446
120Abnormal pupillary function (HP:0007686)1.68515379
121Progressive microcephaly (HP:0000253)1.68430119
122Abnormality of B cell number (HP:0010975)1.68207552
123Severe combined immunodeficiency (HP:0004430)1.66360122
124Gliosis (HP:0002171)1.66256073
125Pancreatic cysts (HP:0001737)1.65871606
126Testicular atrophy (HP:0000029)1.64030862
127Pancreatic fibrosis (HP:0100732)1.63780115
128Acute hepatic failure (HP:0006554)1.62633737
129Vomiting (HP:0002013)1.62335227
130Medial flaring of the eyebrow (HP:0010747)1.61726325
131Abnormality of T cells (HP:0002843)1.61581828
132Obstructive lung disease (HP:0006536)1.57070515
133Chronic obstructive pulmonary disease (HP:0006510)1.57070515
134Increased serum ferritin (HP:0003281)1.56309957
135Premature ovarian failure (HP:0008209)1.54319364
136Abnormal urine phosphate concentration (HP:0012599)1.51180377

Predicted kinase interactions (KEA)

RankGene SetZ-score
1VRK25.26391066
2BUB14.61050765
3NME24.00829600
4STK163.91653780
5EIF2AK13.74643128
6WEE13.22029291
7TLK12.61954908
8PBK2.56852082
9EIF2AK32.42166403
10SRPK12.33110855
11VRK12.26779286
12PIM22.23046888
13TESK22.20495645
14IRAK32.12156402
15IRAK41.86771587
16NUAK11.85607059
17MAP3K121.77015689
18ACVR1B1.74544737
19PLK41.73479018
20MST41.70232941
21CDC71.65534819
22BCKDK1.55278169
23BRSK21.54999667
24RPS6KA41.49159026
25MAP4K21.45877340
26TAOK31.44324895
27NME11.42453677
28ZAK1.38508885
29PDK21.38265769
30DYRK31.37637014
31BLK1.36465112
32MKNK11.33984251
33PLK11.33357294
34ADRBK21.32103813
35TTK1.27836947
36RIPK41.26506310
37KDR1.25715042
38AURKB1.23278225
39MAP4K11.20073895
40TSSK61.14941698
41GRK61.13908999
42STK41.07723937
43AURKA1.04481438
44MAP3K111.03837952
45CDK71.01618205
46NEK21.01496036
47DAPK10.98631711
48NEK90.98250952
49EIF2AK20.97681086
50ILK0.96026258
51TEC0.94316874
52RPS6KB20.94206093
53MKNK20.93681403
54ABL20.93224047
55BMPR20.91841916
56INSRR0.89239107
57ATR0.88887638
58PLK30.87789091
59DAPK30.87599506
60FLT30.87500460
61GRK10.86656997
62LIMK10.84796445
63PASK0.84286941
64IKBKB0.83701266
65PIM10.83228838
66CSNK1G30.82493695
67TESK10.82078293
68TNK20.79929879
69CDK80.78725551
70ITK0.78396990
71MAP3K80.76944004
72MUSK0.76325093
73IRAK10.76236652
74CSNK2A10.76005259
75RPS6KA50.75587797
76BRAF0.75312643
77LRRK20.74671990
78BRSK10.72546845
79DYRK20.69649299
80TBK10.69266473
81BTK0.68810369
82STK100.68643806
83FES0.68383418
84TGFBR10.67133705
85TXK0.66950515
86CSNK2A20.65860093
87CHEK20.65257858
88MAP3K30.64787707
89EPHA20.63349634
90TYK20.62704704
91NLK0.62061368
92NEK10.61486943
93PRKCQ0.60879377
94CSNK1G10.60452700
95GRK70.59957947
96SCYL20.59782302
97CCNB10.58747588
98CDK40.57971310
99MAPKAPK30.56960908
100ZAP700.56902893
101LYN0.56162393
102KIT0.54850639
103MAP2K30.54677667
104ARAF0.53408988
105OBSCN0.52986046
106TRIM280.52120510
107MAP3K140.51194097
108MARK30.50152882
109CDK190.48060184
110CHEK10.47283416
111IKBKE0.46465731
112PAK10.45047324
113CLK10.43939111
114TAF10.43073611
115TAOK20.42981675
116PIK3CG0.42251868
117MAPKAPK50.42017314
118STK240.41429664
119YES10.40289475
120PINK10.39464342
121MAP2K60.38410166
122MYLK0.38047988
123CSNK1G20.37915243
124MAPK110.36825945
125CSNK1A1L0.36820250
126SYK0.36536135
127JAK30.35853097
128ADRBK10.35819730
129IRAK20.34717017
130MELK0.34418296
131CDK20.30388588
132PRKCI0.29617365
133LCK0.29572105
134CDK30.29528270

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030104.58688014
2Proteasome_Homo sapiens_hsa030503.96026575
3DNA replication_Homo sapiens_hsa030303.69652056
4RNA polymerase_Homo sapiens_hsa030203.48689726
5Mismatch repair_Homo sapiens_hsa034303.02828219
6Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.75062790
7Protein export_Homo sapiens_hsa030602.59877554
8Pyrimidine metabolism_Homo sapiens_hsa002402.58923565
9Homologous recombination_Homo sapiens_hsa034402.42429122
10Spliceosome_Homo sapiens_hsa030402.38407257
11Base excision repair_Homo sapiens_hsa034102.35980866
12Nucleotide excision repair_Homo sapiens_hsa034202.18720316
13Oxidative phosphorylation_Homo sapiens_hsa001902.12778072
14Parkinsons disease_Homo sapiens_hsa050121.99853069
15Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.96349469
16RNA transport_Homo sapiens_hsa030131.91684601
17One carbon pool by folate_Homo sapiens_hsa006701.90475007
18Folate biosynthesis_Homo sapiens_hsa007901.76786774
19Basal transcription factors_Homo sapiens_hsa030221.61625733
20Cardiac muscle contraction_Homo sapiens_hsa042601.55503320
21Huntingtons disease_Homo sapiens_hsa050161.48880116
22Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.48544307
23Fanconi anemia pathway_Homo sapiens_hsa034601.38184691
24Cell cycle_Homo sapiens_hsa041101.34971602
25Purine metabolism_Homo sapiens_hsa002301.34186844
26Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.33237213
27Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008601.33172133
28Autoimmune thyroid disease_Homo sapiens_hsa053201.32487901
29RNA degradation_Homo sapiens_hsa030181.30707368
30Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.28620088
31Non-homologous end-joining_Homo sapiens_hsa034501.26855499
32Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.21059907
33Type I diabetes mellitus_Homo sapiens_hsa049401.14443899
34Pentose phosphate pathway_Homo sapiens_hsa000301.08159408
35Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.07968023
36Glutathione metabolism_Homo sapiens_hsa004801.07296435
37Alzheimers disease_Homo sapiens_hsa050101.06852107
38Drug metabolism - other enzymes_Homo sapiens_hsa009831.01585642
39Vitamin B6 metabolism_Homo sapiens_hsa007501.00001496
40Cysteine and methionine metabolism_Homo sapiens_hsa002700.94725125
41Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.91911577
42Rheumatoid arthritis_Homo sapiens_hsa053230.90772079
43Cyanoamino acid metabolism_Homo sapiens_hsa004600.90413077
44Sulfur relay system_Homo sapiens_hsa041220.89370879
45Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.87250259
46p53 signaling pathway_Homo sapiens_hsa041150.86580911
47Epstein-Barr virus infection_Homo sapiens_hsa051690.85914483
48Fatty acid elongation_Homo sapiens_hsa000620.84982564
49Selenocompound metabolism_Homo sapiens_hsa004500.84349758
50Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.83118433
51Collecting duct acid secretion_Homo sapiens_hsa049660.81097280
52Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.80540722
53Systemic lupus erythematosus_Homo sapiens_hsa053220.77366274
54Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.76859027
55Carbon metabolism_Homo sapiens_hsa012000.75185987
56Biosynthesis of amino acids_Homo sapiens_hsa012300.74415718
57Peroxisome_Homo sapiens_hsa041460.74078720
58Steroid biosynthesis_Homo sapiens_hsa001000.73592406
59Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.72152626
60Herpes simplex infection_Homo sapiens_hsa051680.72148075
61Graft-versus-host disease_Homo sapiens_hsa053320.70452563
62Metabolic pathways_Homo sapiens_hsa011000.69699788
63Legionellosis_Homo sapiens_hsa051340.69315106
64Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.69110918
65Antigen processing and presentation_Homo sapiens_hsa046120.67596352
66Primary immunodeficiency_Homo sapiens_hsa053400.59353796
67Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.58708360
68Arachidonic acid metabolism_Homo sapiens_hsa005900.58298679
69Pentose and glucuronate interconversions_Homo sapiens_hsa000400.56905044
70Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.56306606
71mRNA surveillance pathway_Homo sapiens_hsa030150.56163660
72Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.53423653
73Allograft rejection_Homo sapiens_hsa053300.52648352
74RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.50099934
75Propanoate metabolism_Homo sapiens_hsa006400.49221771
76Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.48864619
77Sulfur metabolism_Homo sapiens_hsa009200.48835359
78Arginine and proline metabolism_Homo sapiens_hsa003300.48486034
79Regulation of autophagy_Homo sapiens_hsa041400.47831171
80Intestinal immune network for IgA production_Homo sapiens_hsa046720.47233530
81NF-kappa B signaling pathway_Homo sapiens_hsa040640.46081093
82Chemical carcinogenesis_Homo sapiens_hsa052040.45858479
83SNARE interactions in vesicular transport_Homo sapiens_hsa041300.43114946
84Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.42474411
85Histidine metabolism_Homo sapiens_hsa003400.41985642
86Retinol metabolism_Homo sapiens_hsa008300.39434176
87Asthma_Homo sapiens_hsa053100.39422177
88Fructose and mannose metabolism_Homo sapiens_hsa000510.38911533
892-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.38261975
90Galactose metabolism_Homo sapiens_hsa000520.37795567
91beta-Alanine metabolism_Homo sapiens_hsa004100.37745738
92Primary bile acid biosynthesis_Homo sapiens_hsa001200.37492349
93Pyruvate metabolism_Homo sapiens_hsa006200.36109664
94Measles_Homo sapiens_hsa051620.36011438
95Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.35882884
96Hematopoietic cell lineage_Homo sapiens_hsa046400.35837587
97Fatty acid degradation_Homo sapiens_hsa000710.34745944
98Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.33977802
99Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.33927475
100Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.32981302
101Linoleic acid metabolism_Homo sapiens_hsa005910.32344511
102Maturity onset diabetes of the young_Homo sapiens_hsa049500.31179465
103Tyrosine metabolism_Homo sapiens_hsa003500.30742191
104Butanoate metabolism_Homo sapiens_hsa006500.29954931
105Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.29774422
106Leishmaniasis_Homo sapiens_hsa051400.29482577
107N-Glycan biosynthesis_Homo sapiens_hsa005100.29316300
108Phenylalanine metabolism_Homo sapiens_hsa003600.28062795
109Caffeine metabolism_Homo sapiens_hsa002320.27344942
110Other glycan degradation_Homo sapiens_hsa005110.26609234
111Viral carcinogenesis_Homo sapiens_hsa052030.26424840
112Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.25642104
113Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.25225358
114Malaria_Homo sapiens_hsa051440.25101165
115Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.24825733
116Staphylococcus aureus infection_Homo sapiens_hsa051500.23835853
117Tryptophan metabolism_Homo sapiens_hsa003800.21154131
118alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.20176063
119Viral myocarditis_Homo sapiens_hsa054160.19463772
120Shigellosis_Homo sapiens_hsa051310.17620316

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