Rank | Gene Set | Z-score |
---|---|---|
1 | synaptic vesicle maturation (GO:0016188) | 6.42393935 |
2 | pyrimidine nucleobase catabolic process (GO:0006208) | 5.97995543 |
3 | regulation of short-term neuronal synaptic plasticity (GO:0048172) | 5.96804023 |
4 | positive regulation of calcium ion-dependent exocytosis (GO:0045956) | 5.82363234 |
5 | locomotory exploration behavior (GO:0035641) | 5.36769036 |
6 | presynaptic membrane assembly (GO:0097105) | 5.30956652 |
7 | regulation of synaptic vesicle exocytosis (GO:2000300) | 5.03632824 |
8 | synaptic vesicle exocytosis (GO:0016079) | 4.79024891 |
9 | presynaptic membrane organization (GO:0097090) | 4.74673573 |
10 | neurotransmitter secretion (GO:0007269) | 4.65438388 |
11 | nucleobase catabolic process (GO:0046113) | 4.65318020 |
12 | glutamate secretion (GO:0014047) | 4.57394997 |
13 | positive regulation of excitatory postsynaptic membrane potential (GO:2000463) | 4.51752779 |
14 | layer formation in cerebral cortex (GO:0021819) | 4.41775222 |
15 | regulation of synaptic vesicle transport (GO:1902803) | 4.41325658 |
16 | vocalization behavior (GO:0071625) | 4.40176156 |
17 | proline transport (GO:0015824) | 4.34125648 |
18 | neuronal action potential propagation (GO:0019227) | 4.32539419 |
19 | establishment of mitochondrion localization (GO:0051654) | 4.29486617 |
20 | neuromuscular process controlling posture (GO:0050884) | 4.26175642 |
21 | gamma-aminobutyric acid transport (GO:0015812) | 4.24962848 |
22 | glycine transport (GO:0015816) | 4.20725601 |
23 | synaptic vesicle docking involved in exocytosis (GO:0016081) | 4.17656883 |
24 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act | 4.15094753 |
25 | activation of protein kinase A activity (GO:0034199) | 4.13486349 |
26 | exploration behavior (GO:0035640) | 4.10003938 |
27 | regulation of glutamate receptor signaling pathway (GO:1900449) | 4.07171947 |
28 | sodium ion export (GO:0071436) | 4.06890296 |
29 | cellular potassium ion homeostasis (GO:0030007) | 4.03515974 |
30 | neuron cell-cell adhesion (GO:0007158) | 4.00675483 |
31 | positive regulation of synaptic transmission, GABAergic (GO:0032230) | 3.97110134 |
32 | regulation of neuronal synaptic plasticity (GO:0048168) | 3.96306354 |
33 | regulation of synapse structural plasticity (GO:0051823) | 3.96061221 |
34 | positive regulation of synaptic transmission, dopaminergic (GO:0032226) | 3.94336231 |
35 | protein localization to synapse (GO:0035418) | 3.88774439 |
36 | regulation of long-term neuronal synaptic plasticity (GO:0048169) | 3.85470274 |
37 | neurotransmitter transport (GO:0006836) | 3.79266183 |
38 | cerebellar Purkinje cell differentiation (GO:0021702) | 3.73251069 |
39 | cell communication by electrical coupling involved in cardiac conduction (GO:0086064) | 3.72155836 |
40 | dendritic spine morphogenesis (GO:0060997) | 3.69051227 |
41 | neuromuscular process controlling balance (GO:0050885) | 3.66703292 |
42 | establishment of mitochondrion localization, microtubule-mediated (GO:0034643) | 3.66660016 |
43 | mitochondrion transport along microtubule (GO:0047497) | 3.66660016 |
44 | mechanosensory behavior (GO:0007638) | 3.64862071 |
45 | negative regulation of synaptic transmission, glutamatergic (GO:0051967) | 3.61415756 |
46 | ionotropic glutamate receptor signaling pathway (GO:0035235) | 3.60510989 |
47 | vesicle transport along microtubule (GO:0047496) | 3.56762816 |
48 | cell communication by electrical coupling (GO:0010644) | 3.55756701 |
49 | axon cargo transport (GO:0008088) | 3.51824204 |
50 | regulation of neurotransmitter levels (GO:0001505) | 3.51300176 |
51 | negative regulation of amyloid precursor protein catabolic process (GO:1902992) | 3.51074863 |
52 | membrane depolarization during cardiac muscle cell action potential (GO:0086012) | 3.50020418 |
53 | cell migration in hindbrain (GO:0021535) | 3.49792775 |
54 | mating behavior (GO:0007617) | 3.48810222 |
55 | regulation of inhibitory postsynaptic membrane potential (GO:0060080) | 3.42335274 |
56 | short-term memory (GO:0007614) | 3.40854985 |
57 | prepulse inhibition (GO:0060134) | 3.40185882 |
58 | cerebellar Purkinje cell layer development (GO:0021680) | 3.36883407 |
59 | regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310) | 3.35857832 |
60 | synapse assembly (GO:0007416) | 3.34412869 |
61 | potassium ion homeostasis (GO:0055075) | 3.30084431 |
62 | positive regulation of potassium ion transmembrane transporter activity (GO:1901018) | 3.28738752 |
63 | positive regulation of synapse assembly (GO:0051965) | 3.27745230 |
64 | response to auditory stimulus (GO:0010996) | 3.27472015 |
65 | membrane depolarization during action potential (GO:0086010) | 3.26480008 |
66 | dendrite morphogenesis (GO:0048813) | 3.24190521 |
67 | synaptic transmission, glutamatergic (GO:0035249) | 3.23138295 |
68 | regulation of respiratory gaseous exchange by neurological system process (GO:0002087) | 3.20832656 |
69 | organelle transport along microtubule (GO:0072384) | 3.19666795 |
70 | neuronal ion channel clustering (GO:0045161) | 3.19143868 |
71 | long-term memory (GO:0007616) | 3.18589412 |
72 | regulation of cAMP-dependent protein kinase activity (GO:2000479) | 3.18113962 |
73 | neuron-neuron synaptic transmission (GO:0007270) | 3.17744261 |
74 | potassium ion import (GO:0010107) | 3.17558867 |
75 | adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191) | 3.15557350 |
76 | transmission of nerve impulse (GO:0019226) | 3.15407359 |
77 | auditory behavior (GO:0031223) | 3.15227970 |
78 | neuron recognition (GO:0008038) | 3.13006245 |
79 | positive regulation of potassium ion transmembrane transport (GO:1901381) | 3.11110175 |
80 | regulation of neurotransmitter secretion (GO:0046928) | 3.10229256 |
81 | axon extension (GO:0048675) | 3.08276411 |
82 | axonal fasciculation (GO:0007413) | 3.08064404 |
83 | positive regulation of membrane potential (GO:0045838) | 3.07311897 |
84 | glutamate receptor signaling pathway (GO:0007215) | 3.06979316 |
85 | negative regulation of microtubule polymerization (GO:0031115) | 3.06131064 |
86 | synaptic vesicle endocytosis (GO:0048488) | 3.06112659 |
87 | positive regulation of synaptic transmission, glutamatergic (GO:0051968) | 3.05503421 |
88 | regulation of vesicle fusion (GO:0031338) | 3.04756518 |
89 | neurotransmitter-gated ion channel clustering (GO:0072578) | 3.03959634 |
90 | neuromuscular process (GO:0050905) | 3.01862416 |
91 | synapse organization (GO:0050808) | 3.00934899 |
92 | membrane hyperpolarization (GO:0060081) | 3.00808266 |
93 | dopamine receptor signaling pathway (GO:0007212) | 3.00798245 |
94 | response to pheromone (GO:0019236) | 2.99999973 |
95 | regulation of neurotransmitter transport (GO:0051588) | 2.98783849 |
96 | regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371) | 2.98728087 |
97 | positive regulation of dendritic spine morphogenesis (GO:0061003) | 2.98030051 |
98 | innervation (GO:0060384) | 2.97548448 |
99 | gamma-aminobutyric acid signaling pathway (GO:0007214) | 2.96730584 |
100 | regulation of synaptic plasticity (GO:0048167) | 2.90032737 |
101 | regulation of ARF protein signal transduction (GO:0032012) | 2.88123837 |
102 | regulation of excitatory postsynaptic membrane potential (GO:0060079) | 2.88025508 |
103 | axon extension involved in axon guidance (GO:0048846) | 2.86945187 |
104 | neuron projection extension involved in neuron projection guidance (GO:1902284) | 2.86945187 |
105 | membrane repolarization (GO:0086009) | 2.86551225 |
106 | regulation of calcium ion-dependent exocytosis (GO:0017158) | 2.86550622 |
107 | neurofilament cytoskeleton organization (GO:0060052) | 2.86497792 |
108 | alanine transport (GO:0032328) | 2.84876171 |
109 | regulation of synaptic transmission, GABAergic (GO:0032228) | 2.84835294 |
110 | regulation of postsynaptic membrane potential (GO:0060078) | 2.84403216 |
111 | adult walking behavior (GO:0007628) | 2.83888893 |
112 | positive regulation of potassium ion transport (GO:0043268) | 2.81039533 |
113 | dendritic spine organization (GO:0097061) | 2.80734446 |
114 | postsynaptic membrane organization (GO:0001941) | 2.79792073 |
115 | cerebellar granule cell differentiation (GO:0021707) | 2.79707527 |
116 | signal release (GO:0023061) | 2.78085777 |
117 | regulation of synaptic transmission, glutamatergic (GO:0051966) | 2.77990103 |
118 | suckling behavior (GO:0001967) | 2.77735074 |
119 | establishment of nucleus localization (GO:0040023) | 2.76949300 |
120 | positive regulation of neurotransmitter transport (GO:0051590) | 2.76703971 |
121 | G-protein coupled glutamate receptor signaling pathway (GO:0007216) | 2.75811325 |
122 | regulation of feeding behavior (GO:0060259) | 2.75467279 |
123 | social behavior (GO:0035176) | 2.75391260 |
124 | intraspecies interaction between organisms (GO:0051703) | 2.75391260 |
125 | retinal ganglion cell axon guidance (GO:0031290) | 2.73642061 |
126 | neuromuscular synaptic transmission (GO:0007274) | 2.72045219 |
127 | positive regulation of synapse maturation (GO:0090129) | 2.70166575 |
128 | regulation of dendritic spine morphogenesis (GO:0061001) | 2.69807162 |
129 | positive regulation of dendritic spine development (GO:0060999) | 2.69253972 |
130 | central nervous system projection neuron axonogenesis (GO:0021952) | 2.66123325 |
131 | neuron projection extension (GO:1990138) | 2.64561318 |
132 | neurotransmitter uptake (GO:0001504) | 2.58225704 |
133 | membrane assembly (GO:0071709) | 2.58141938 |
134 | negative regulation of synaptic transmission, GABAergic (GO:0032229) | 2.56144020 |
135 | regulation of voltage-gated calcium channel activity (GO:1901385) | 2.54869522 |
Rank | Gene Set | Z-score |
---|---|---|
1 | EZH2_22144423_ChIP-Seq_EOC_Human | 5.64966181 |
2 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 2.99574013 |
3 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 2.95321499 |
4 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 2.81501167 |
5 | * REST_21632747_ChIP-Seq_MESCs_Mouse | 2.81356723 |
6 | GBX2_23144817_ChIP-Seq_PC3_Human | 2.75617840 |
7 | DROSHA_22980978_ChIP-Seq_HELA_Human | 2.67368131 |
8 | RARB_27405468_Chip-Seq_BRAIN_Mouse | 2.66867863 |
9 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 2.65350588 |
10 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 2.65350588 |
11 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 2.58168109 |
12 | * SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 2.54812432 |
13 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 2.51018768 |
14 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 2.49647475 |
15 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 2.45504338 |
16 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 2.44193278 |
17 | EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 2.42737323 |
18 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 2.37191000 |
19 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 2.35990519 |
20 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 2.35876513 |
21 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 2.28186963 |
22 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 2.25014916 |
23 | * SUZ12_27294783_Chip-Seq_ESCs_Mouse | 2.23145800 |
24 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 2.16505161 |
25 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 2.14696779 |
26 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 2.14130406 |
27 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 2.11311815 |
28 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 2.06218688 |
29 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 2.00461826 |
30 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.90309502 |
31 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.81974689 |
32 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.79435058 |
33 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.77136876 |
34 | GATA1_26923725_Chip-Seq_HPCs_Mouse | 1.76378587 |
35 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 1.76116936 |
36 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.65987912 |
37 | ZFP281_18757296_ChIP-ChIP_E14_Mouse | 1.59690492 |
38 | NANOG_18700969_ChIP-ChIP_MESCs_Mouse | 1.51449902 |
39 | NR3C1_23031785_ChIP-Seq_PC12_Mouse | 1.50281314 |
40 | RCOR3_21632747_ChIP-Seq_MESCs_Mouse | 1.48260474 |
41 | DNAJC2_21179169_ChIP-ChIP_NT2_Human | 1.47746202 |
42 | KDM2B_26808549_Chip-Seq_K562_Human | 1.47592559 |
43 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.45591872 |
44 | * SMAD4_21799915_ChIP-Seq_A2780_Human | 1.43492230 |
45 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.41548760 |
46 | RING1B_27294783_Chip-Seq_ESCs_Mouse | 1.36748923 |
47 | EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human | 1.35479325 |
48 | SOX2_21211035_ChIP-Seq_LN229_Gbm | 1.31327268 |
49 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.30681582 |
50 | WT1_25993318_ChIP-Seq_PODOCYTE_Human | 1.29370191 |
51 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 1.29235721 |
52 | * SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.28977742 |
53 | AR_19668381_ChIP-Seq_PC3_Human | 1.28216408 |
54 | WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse | 1.26778695 |
55 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 1.26596389 |
56 | ZFP281_18358816_ChIP-ChIP_MESCs_Mouse | 1.25347941 |
57 | WT1_19549856_ChIP-ChIP_CCG9911_Human | 1.24468760 |
58 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.23530639 |
59 | TCF3_18467660_ChIP-ChIP_MESCs_Mouse | 1.22119908 |
60 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 1.20919313 |
61 | * STAT3_23295773_ChIP-Seq_U87_Human | 1.19051315 |
62 | CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.17669995 |
63 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 1.17669230 |
64 | * SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.17142253 |
65 | ESRRB_18555785_ChIP-Seq_MESCs_Mouse | 1.15309837 |
66 | SOX9_26525672_Chip-Seq_HEART_Mouse | 1.14172123 |
67 | POU5F1_18347094_ChIP-ChIP_MESCs_Mouse | 1.14040183 |
68 | KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse | 1.13590475 |
69 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.12794780 |
70 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.12646342 |
71 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.12646342 |
72 | OLIG2_26023283_ChIP-Seq_AINV15_Mouse | 1.12233148 |
73 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.12059087 |
74 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 1.11921776 |
75 | EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse | 1.11673068 |
76 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.11139648 |
77 | RING1B_27294783_Chip-Seq_NPCs_Mouse | 1.10619685 |
78 | SOX2_18358816_ChIP-ChIP_MESCs_Mouse | 1.10293004 |
79 | ZFP281_27345836_Chip-Seq_ESCs_Mouse | 1.09669045 |
80 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.09176641 |
81 | SALL4_18804426_ChIP-ChIP_MESCs_Mouse | 1.08709422 |
82 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.08545574 |
83 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.08539578 |
84 | FUS_26573619_Chip-Seq_HEK293_Human | 1.08056902 |
85 | YAP1_20516196_ChIP-Seq_MESCs_Mouse | 1.06433077 |
86 | DMRT1_23473982_ChIP-Seq_TESTES_Mouse | 1.05941676 |
87 | STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse | 1.05502017 |
88 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.05386099 |
89 | GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.04110286 |
90 | * SMAD3_21741376_ChIP-Seq_ESCs_Human | 1.03700578 |
91 | TBX3_20139965_ChIP-Seq_MESCs_Mouse | 1.02253889 |
92 | TET1_21490601_ChIP-Seq_MESCs_Mouse | 1.01574612 |
93 | TBX3_20139965_ChIP-Seq_ESCs_Mouse | 1.01307840 |
94 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.00658960 |
95 | AHR_22903824_ChIP-Seq_MCF-7_Human | 1.00504084 |
96 | SMAD4_21741376_ChIP-Seq_HESCs_Human | 1.00139270 |
97 | CTCF_27219007_Chip-Seq_Bcells_Human | 0.99680254 |
98 | * MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 0.99126433 |
99 | * ZNF217_24962896_ChIP-Seq_MCF-7_Human | 0.98451481 |
100 | RCOR2_21632747_ChIP-Seq_MESCs_Mouse | 0.98426965 |
101 | * AR_25329375_ChIP-Seq_VCAP_Human | 0.98113634 |
102 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 0.97004518 |
103 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 0.95833107 |
104 | ISL1_27105846_Chip-Seq_CPCs_Mouse | 0.95436127 |
105 | * TOP2B_26459242_ChIP-Seq_MCF-7_Human | 0.95059128 |
106 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 0.93479636 |
107 | JUN_21703547_ChIP-Seq_K562_Human | 0.93230354 |
108 | * P300_19829295_ChIP-Seq_ESCs_Human | 0.93134125 |
109 | * TCF4_23295773_ChIP-Seq_U87_Human | 0.92802420 |
110 | LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.92564232 |
111 | CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse | 0.92155494 |
112 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.92010639 |
113 | P53_22127205_ChIP-Seq_FIBROBLAST_Human | 0.90264018 |
114 | TRIM28_17542650_ChIP-ChIP_NTERA2_Human | 0.90256089 |
115 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 0.90122764 |
116 | MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse | 0.88926900 |
117 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 0.87796143 |
118 | BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 0.87216426 |
119 | KLF4_19829295_ChIP-Seq_ESCs_Human | 0.87143453 |
120 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 0.86561038 |
121 | ESR1_22446102_ChIP-Seq_UTERUS_Mouse | 0.85778288 |
122 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 0.84893843 |
123 | SMAD3_22036565_ChIP-Seq_ESCs_Mouse | 0.84564920 |
124 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 0.83044367 |
125 | TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.82564984 |
126 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 0.82250775 |
127 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 0.82002224 |
128 | RNF2_27304074_Chip-Seq_NSC_Mouse | 0.81770581 |
129 | * RUNX2_22187159_ChIP-Seq_PCA_Human | 0.80368179 |
130 | SMAD3_21741376_ChIP-Seq_HESCs_Human | 0.80030841 |
131 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 0.79561189 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0004859_abnormal_synaptic_plasticity | 5.31727994 |
2 | MP0003880_abnormal_central_pattern | 3.94136649 |
3 | MP0003635_abnormal_synaptic_transmissio | 3.71951757 |
4 | MP0004270_analgesia | 3.68069807 |
5 | MP0005423_abnormal_somatic_nervous | 3.34733945 |
6 | MP0001968_abnormal_touch/_nociception | 3.14501197 |
7 | MP0009046_muscle_twitch | 3.09960199 |
8 | MP0009745_abnormal_behavioral_response | 2.92432213 |
9 | MP0002063_abnormal_learning/memory/cond | 2.81692623 |
10 | MP0002064_seizures | 2.81042193 |
11 | MP0002734_abnormal_mechanical_nocicepti | 2.77775989 |
12 | MP0002822_catalepsy | 2.58409417 |
13 | MP0002909_abnormal_adrenal_gland | 2.54472831 |
14 | MP0002272_abnormal_nervous_system | 2.44826833 |
15 | MP0002733_abnormal_thermal_nociception | 2.40112571 |
16 | MP0002572_abnormal_emotion/affect_behav | 2.39637517 |
17 | MP0003122_maternal_imprinting | 2.34943053 |
18 | MP0004858_abnormal_nervous_system | 2.29152166 |
19 | MP0006276_abnormal_autonomic_nervous | 2.24773072 |
20 | MP0001486_abnormal_startle_reflex | 2.18969970 |
21 | MP0002735_abnormal_chemical_nociception | 2.15665160 |
22 | MP0005645_abnormal_hypothalamus_physiol | 2.14144864 |
23 | MP0002102_abnormal_ear_morphology | 2.13110158 |
24 | MP0001970_abnormal_pain_threshold | 2.08580149 |
25 | MP0002736_abnormal_nociception_after | 2.08465533 |
26 | MP0001501_abnormal_sleep_pattern | 2.00870377 |
27 | MP0000566_synostosis | 1.95522103 |
28 | MP0002067_abnormal_sensory_capabilities | 1.94216056 |
29 | MP0002184_abnormal_innervation | 1.93752392 |
30 | MP0004811_abnormal_neuron_physiology | 1.90014386 |
31 | MP0009780_abnormal_chondrocyte_physiolo | 1.89617645 |
32 | MP0003787_abnormal_imprinting | 1.85793294 |
33 | MP0008569_lethality_at_weaning | 1.82855215 |
34 | MP0003283_abnormal_digestive_organ | 1.80774466 |
35 | MP0005646_abnormal_pituitary_gland | 1.77207581 |
36 | MP0000955_abnormal_spinal_cord | 1.75246545 |
37 | MP0001440_abnormal_grooming_behavior | 1.72107564 |
38 | MP0003329_amyloid_beta_deposits | 1.71804454 |
39 | MP0002557_abnormal_social/conspecific_i | 1.71279082 |
40 | MP0004924_abnormal_behavior | 1.63731136 |
41 | MP0005386_behavior/neurological_phenoty | 1.63731136 |
42 | MP0000013_abnormal_adipose_tissue | 1.59938807 |
43 | MP0000778_abnormal_nervous_system | 1.59604321 |
44 | MP0000569_abnormal_digit_pigmentation | 1.58872797 |
45 | MP0004885_abnormal_endolymph | 1.53533207 |
46 | MP0001188_hyperpigmentation | 1.52110719 |
47 | MP0002882_abnormal_neuron_morphology | 1.46112914 |
48 | MP0008961_abnormal_basal_metabolism | 1.43907057 |
49 | MP0003011_delayed_dark_adaptation | 1.40636547 |
50 | MP0004142_abnormal_muscle_tone | 1.40524085 |
51 | MP0005248_abnormal_Harderian_gland | 1.39373787 |
52 | MP0002066_abnormal_motor_capabilities/c | 1.38100797 |
53 | MP0003633_abnormal_nervous_system | 1.37250749 |
54 | MP0006292_abnormal_olfactory_placode | 1.31786788 |
55 | MP0010030_abnormal_orbit_morphology | 1.31752913 |
56 | MP0003123_paternal_imprinting | 1.31574336 |
57 | MP0008789_abnormal_olfactory_epithelium | 1.27719012 |
58 | MP0001984_abnormal_olfaction | 1.24488455 |
59 | MP0001502_abnormal_circadian_rhythm | 1.21218657 |
60 | MP0003634_abnormal_glial_cell | 1.19002572 |
61 | MP0001299_abnormal_eye_distance/ | 1.18957421 |
62 | MP0003861_abnormal_nervous_system | 1.18537570 |
63 | MP0002229_neurodegeneration | 1.17548175 |
64 | MP0004145_abnormal_muscle_electrophysio | 1.13591583 |
65 | MP0003631_nervous_system_phenotype | 1.13258594 |
66 | MP0008877_abnormal_DNA_methylation | 1.10433975 |
67 | MP0001293_anophthalmia | 1.08624620 |
68 | MP0001529_abnormal_vocalization | 1.08444021 |
69 | MP0003136_yellow_coat_color | 1.07854522 |
70 | MP0004133_heterotaxia | 1.07349386 |
71 | MP0000537_abnormal_urethra_morphology | 1.05764792 |
72 | MP0000049_abnormal_middle_ear | 1.05095937 |
73 | MP0002152_abnormal_brain_morphology | 1.04724425 |
74 | MP0000751_myopathy | 1.03823286 |
75 | MP0003879_abnormal_hair_cell | 1.02216079 |
76 | MP0003938_abnormal_ear_development | 1.01492910 |
77 | MP0002751_abnormal_autonomic_nervous | 1.00223548 |
78 | MP0003119_abnormal_digestive_system | 1.00129152 |
79 | MP0000920_abnormal_myelination | 0.99349181 |
80 | MP0002653_abnormal_ependyma_morphology | 0.97875163 |
81 | MP0000026_abnormal_inner_ear | 0.96996911 |
82 | MP0003690_abnormal_glial_cell | 0.95770797 |
83 | MP0002638_abnormal_pupillary_reflex | 0.94897921 |
84 | MP0002233_abnormal_nose_morphology | 0.93508576 |
85 | MP0002069_abnormal_eating/drinking_beha | 0.92792849 |
86 | MP0005551_abnormal_eye_electrophysiolog | 0.92197190 |
87 | MP0003121_genomic_imprinting | 0.91969472 |
88 | MP0003937_abnormal_limbs/digits/tail_de | 0.91815176 |
89 | MP0003172_abnormal_lysosome_physiology | 0.90353882 |
90 | MP0001485_abnormal_pinna_reflex | 0.89717125 |
91 | MP0000579_abnormal_nail_morphology | 0.89699072 |
92 | MP0003632_abnormal_nervous_system | 0.89686729 |
93 | MP0003942_abnormal_urinary_system | 0.89091295 |
94 | MP0001905_abnormal_dopamine_level | 0.88646737 |
95 | MP0001963_abnormal_hearing_physiology | 0.88346039 |
96 | MP0003183_abnormal_peptide_metabolism | 0.88148941 |
97 | MP0004233_abnormal_muscle_weight | 0.86510882 |
98 | MP0006072_abnormal_retinal_apoptosis | 0.86060542 |
99 | MP0005535_abnormal_body_temperature | 0.83860131 |
100 | MP0002938_white_spotting | 0.82764199 |
101 | MP0009672_abnormal_birth_weight | 0.81931709 |
102 | MP0002752_abnormal_somatic_nervous | 0.81733793 |
103 | MP0000631_abnormal_neuroendocrine_gland | 0.81292205 |
104 | MP0003045_fibrosis | 0.80902329 |
105 | MP0001348_abnormal_lacrimal_gland | 0.80819253 |
106 | MP0001346_abnormal_lacrimal_gland | 0.79753018 |
107 | MP0005623_abnormal_meninges_morphology | 0.79600231 |
108 | MP0004043_abnormal_pH_regulation | 0.79368636 |
109 | MP0010386_abnormal_urinary_bladder | 0.78565139 |
110 | MP0005187_abnormal_penis_morphology | 0.78429888 |
111 | MP0004085_abnormal_heartbeat | 0.77746589 |
112 | MP0005394_taste/olfaction_phenotype | 0.77527270 |
113 | MP0005499_abnormal_olfactory_system | 0.77527270 |
114 | MP0003890_abnormal_embryonic-extraembry | 0.77041205 |
115 | MP0002697_abnormal_eye_size | 0.76982471 |
116 | MP0005253_abnormal_eye_physiology | 0.73806768 |
117 | MP0008872_abnormal_physiological_respon | 0.73344148 |
118 | MP0000747_muscle_weakness | 0.72950170 |
119 | MP0000003_abnormal_adipose_tissue | 0.72758836 |
120 | MP0005167_abnormal_blood-brain_barrier | 0.70724943 |
121 | MP0001177_atelectasis | 0.69036409 |
122 | MP0008874_decreased_physiological_sensi | 0.68145188 |
123 | MP0000534_abnormal_ureter_morphology | 0.67768876 |
124 | MP0000604_amyloidosis | 0.67003987 |
125 | MP0003137_abnormal_impulse_conducting | 0.66782098 |
126 | MP0004742_abnormal_vestibular_system | 0.66207468 |
127 | MP0001986_abnormal_taste_sensitivity | 0.62073309 |
128 | MP0002090_abnormal_vision | 0.61416060 |
129 | MP0000639_abnormal_adrenal_gland | 0.60605121 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Myokymia (HP:0002411) | 6.00806669 |
2 | Focal motor seizures (HP:0011153) | 5.32262408 |
3 | Action tremor (HP:0002345) | 5.28658789 |
4 | Visual hallucinations (HP:0002367) | 4.74317382 |
5 | Focal seizures (HP:0007359) | 4.54080607 |
6 | Supranuclear gaze palsy (HP:0000605) | 4.12039107 |
7 | Ankle clonus (HP:0011448) | 3.85798226 |
8 | Progressive cerebellar ataxia (HP:0002073) | 3.71534703 |
9 | Elevated circulating parathyroid hormone (PTH) level (HP:0003165) | 3.57182954 |
10 | Cortical dysplasia (HP:0002539) | 3.54944109 |
11 | Pheochromocytoma (HP:0002666) | 3.52812648 |
12 | Insidious onset (HP:0003587) | 3.51266592 |
13 | Termporal pattern (HP:0011008) | 3.51266592 |
14 | Papilledema (HP:0001085) | 3.50165049 |
15 | Depression (HP:0000716) | 3.42593522 |
16 | Atonic seizures (HP:0010819) | 3.36555057 |
17 | Ulnar claw (HP:0001178) | 3.29198815 |
18 | Absence seizures (HP:0002121) | 3.28397596 |
19 | Epileptic encephalopathy (HP:0200134) | 3.27863191 |
20 | Agitation (HP:0000713) | 3.14638813 |
21 | Generalized tonic-clonic seizures (HP:0002069) | 3.09391259 |
22 | Abnormality of the labia minora (HP:0012880) | 3.07730120 |
23 | Febrile seizures (HP:0002373) | 3.06752107 |
24 | Mutism (HP:0002300) | 3.01008211 |
25 | Postural instability (HP:0002172) | 2.99540455 |
26 | Truncal ataxia (HP:0002078) | 2.98650832 |
27 | Neuroendocrine neoplasm (HP:0100634) | 2.97242045 |
28 | Urinary bladder sphincter dysfunction (HP:0002839) | 2.96536421 |
29 | Anxiety (HP:0000739) | 2.93856235 |
30 | Abnormal eating behavior (HP:0100738) | 2.84360745 |
31 | Dialeptic seizures (HP:0011146) | 2.84352066 |
32 | Hypercortisolism (HP:0001578) | 2.83843889 |
33 | Impaired vibration sensation in the lower limbs (HP:0002166) | 2.81831698 |
34 | Ventricular fibrillation (HP:0001663) | 2.74776584 |
35 | Urinary urgency (HP:0000012) | 2.72038899 |
36 | Postural tremor (HP:0002174) | 2.71547333 |
37 | Insomnia (HP:0100785) | 2.68309624 |
38 | Dysdiadochokinesis (HP:0002075) | 2.67928385 |
39 | Spastic gait (HP:0002064) | 2.66965449 |
40 | Failure to thrive in infancy (HP:0001531) | 2.65629367 |
41 | Poor eye contact (HP:0000817) | 2.64053896 |
42 | Genetic anticipation (HP:0003743) | 2.62670179 |
43 | Aplasia involving bones of the extremities (HP:0009825) | 2.61613257 |
44 | Aplasia involving bones of the upper limbs (HP:0009823) | 2.61613257 |
45 | Aplasia of the phalanges of the hand (HP:0009802) | 2.61613257 |
46 | Sleep apnea (HP:0010535) | 2.59982269 |
47 | Torticollis (HP:0000473) | 2.59714591 |
48 | Menstrual irregularities (HP:0000858) | 2.59191764 |
49 | Septo-optic dysplasia (HP:0100842) | 2.58808380 |
50 | Abnormal social behavior (HP:0012433) | 2.51971014 |
51 | Impaired social interactions (HP:0000735) | 2.51971014 |
52 | Hemiplegia (HP:0002301) | 2.48779939 |
53 | Abnormality of the lower motor neuron (HP:0002366) | 2.47887294 |
54 | Abnormality of calcium-phosphate metabolism (HP:0100530) | 2.47059229 |
55 | Dysmetria (HP:0001310) | 2.44675094 |
56 | Hypoventilation (HP:0002791) | 2.44050772 |
57 | Limb dystonia (HP:0002451) | 2.42310470 |
58 | Abnormality of the corticospinal tract (HP:0002492) | 2.39475828 |
59 | Intention tremor (HP:0002080) | 2.39422359 |
60 | Macroorchidism (HP:0000053) | 2.38999916 |
61 | Split foot (HP:0001839) | 2.36794001 |
62 | Broad-based gait (HP:0002136) | 2.35424391 |
63 | Impaired smooth pursuit (HP:0007772) | 2.35212158 |
64 | Peripheral hypomyelination (HP:0007182) | 2.34867370 |
65 | Gait imbalance (HP:0002141) | 2.34332117 |
66 | Scanning speech (HP:0002168) | 2.30053264 |
67 | Hemiparesis (HP:0001269) | 2.29775426 |
68 | Hammertoe (HP:0001765) | 2.28890456 |
69 | Bradykinesia (HP:0002067) | 2.28618399 |
70 | Turricephaly (HP:0000262) | 2.28065625 |
71 | Hepatoblastoma (HP:0002884) | 2.28055149 |
72 | Lower limb muscle weakness (HP:0007340) | 2.27818490 |
73 | Gaze-evoked nystagmus (HP:0000640) | 2.26862353 |
74 | Neoplasm of the peripheral nervous system (HP:0100007) | 2.22335148 |
75 | Progressive inability to walk (HP:0002505) | 2.21935334 |
76 | Pointed chin (HP:0000307) | 2.20476872 |
77 | Focal dystonia (HP:0004373) | 2.19100267 |
78 | Hand muscle atrophy (HP:0009130) | 2.18150022 |
79 | Excessive salivation (HP:0003781) | 2.17309493 |
80 | Drooling (HP:0002307) | 2.17309493 |
81 | Clonus (HP:0002169) | 2.16166123 |
82 | Craniofacial dystonia (HP:0012179) | 2.12609646 |
83 | Intestinal atresia (HP:0011100) | 2.12394187 |
84 | Neurofibrillary tangles (HP:0002185) | 2.11469316 |
85 | EEG with generalized epileptiform discharges (HP:0011198) | 2.11310023 |
86 | Megalencephaly (HP:0001355) | 2.10954556 |
87 | Hypsarrhythmia (HP:0002521) | 2.10477649 |
88 | Amblyopia (HP:0000646) | 2.09485059 |
89 | Decreased number of large peripheral myelinated nerve fibers (HP:0003387) | 2.07293530 |
90 | Neoplasm of the heart (HP:0100544) | 2.06396426 |
91 | Epileptiform EEG discharges (HP:0011182) | 2.04947472 |
92 | Optic nerve hypoplasia (HP:0000609) | 2.04564285 |
93 | Hyperacusis (HP:0010780) | 2.03689055 |
94 | Bronchomalacia (HP:0002780) | 2.03320596 |
95 | Segmental peripheral demyelination/remyelination (HP:0003481) | 2.02989641 |
96 | Abnormality of ocular smooth pursuit (HP:0000617) | 2.02582218 |
97 | Degeneration of the lateral corticospinal tracts (HP:0002314) | 2.01958499 |
98 | Atrophy/Degeneration involving the corticospinal tracts (HP:0007372) | 2.01958499 |
99 | Humeroradial synostosis (HP:0003041) | 2.01950304 |
100 | Synostosis involving the elbow (HP:0003938) | 2.01950304 |
101 | Onion bulb formation (HP:0003383) | 1.99323004 |
102 | Aplasia/Hypoplasia of the brainstem (HP:0007362) | 1.98817371 |
103 | Hypoplasia of the brainstem (HP:0002365) | 1.98817371 |
104 | Poor suck (HP:0002033) | 1.98521738 |
105 | Cerebral inclusion bodies (HP:0100314) | 1.97812432 |
106 | Neuronal loss in central nervous system (HP:0002529) | 1.97599189 |
107 | Polyphagia (HP:0002591) | 1.94736436 |
108 | Aqueductal stenosis (HP:0002410) | 1.94701342 |
109 | Specific learning disability (HP:0001328) | 1.94687508 |
110 | Dysmetric saccades (HP:0000641) | 1.92998706 |
111 | Abnormal EKG (HP:0003115) | 1.91280473 |
112 | Spastic tetraplegia (HP:0002510) | 1.90523174 |
113 | Trigonocephaly (HP:0000243) | 1.89855615 |
114 | Absent septum pellucidum (HP:0001331) | 1.88436638 |
115 | Psychosis (HP:0000709) | 1.87208989 |
116 | Cutaneous finger syndactyly (HP:0010554) | 1.86192716 |
117 | Impaired pain sensation (HP:0007328) | 1.84648311 |
118 | Abnormality of pain sensation (HP:0010832) | 1.84648311 |
119 | Vaginal atresia (HP:0000148) | 1.84637654 |
120 | Rapidly progressive (HP:0003678) | 1.83921167 |
121 | Morphological abnormality of the pyramidal tract (HP:0002062) | 1.82597501 |
122 | Restlessness (HP:0000711) | 1.82115977 |
123 | Abnormality of binocular vision (HP:0011514) | 1.81984507 |
124 | Diplopia (HP:0000651) | 1.81984507 |
125 | Genital tract atresia (HP:0001827) | 1.81806990 |
126 | Fetal akinesia sequence (HP:0001989) | 1.80800368 |
127 | Cutaneous syndactyly (HP:0012725) | 1.80382151 |
128 | Blue irides (HP:0000635) | 1.80315544 |
129 | Bundle branch block (HP:0011710) | 1.79326557 |
130 | Gait ataxia (HP:0002066) | 1.79289203 |
131 | Amyotrophic lateral sclerosis (HP:0007354) | 1.79240059 |
132 | Atrophy/Degeneration involving motor neurons (HP:0007373) | 1.79036140 |
133 | Stereotypic behavior (HP:0000733) | 1.79033387 |
134 | Prolonged QT interval (HP:0001657) | 1.78869617 |
135 | Alacrima (HP:0000522) | 1.77739452 |
136 | Oligodactyly (hands) (HP:0001180) | 1.77708411 |
137 | Akinesia (HP:0002304) | 1.76878350 |
138 | Aplasia/Hypoplasia of the optic nerve (HP:0008058) | 1.74635123 |
139 | Broad foot (HP:0001769) | 1.74478745 |
140 | Choanal stenosis (HP:0000452) | 1.73051240 |
141 | Generalized hypotonia (HP:0001290) | 1.70181188 |
142 | Retinal dysplasia (HP:0007973) | 1.70003127 |
143 | Lissencephaly (HP:0001339) | 1.69921271 |
144 | Overriding aorta (HP:0002623) | 1.67240313 |
145 | Esotropia (HP:0000565) | 1.66095338 |
Rank | Gene Set | Z-score |
---|---|---|
1 | NTRK3 | 4.60800002 |
2 | MAP3K9 | 4.16758432 |
3 | MARK1 | 3.33430995 |
4 | MAP3K4 | 3.15911973 |
5 | MINK1 | 3.09748004 |
6 | NTRK1 | 2.55017797 |
7 | DYRK2 | 2.44901430 |
8 | PAK6 | 2.39366766 |
9 | EPHA4 | 2.36190646 |
10 | KSR2 | 2.35532531 |
11 | NTRK2 | 2.23094135 |
12 | MAP2K7 | 2.17173387 |
13 | PRKD3 | 2.05985811 |
14 | MAP2K4 | 1.98962369 |
15 | CAMKK1 | 1.90464895 |
16 | MAP3K12 | 1.88935370 |
17 | LMTK2 | 1.72833846 |
18 | UHMK1 | 1.69739555 |
19 | FGFR2 | 1.66256239 |
20 | KSR1 | 1.64983866 |
21 | MAP3K2 | 1.63365890 |
22 | DAPK2 | 1.56509402 |
23 | CDK5 | 1.53182498 |
24 | CSNK1G3 | 1.44434721 |
25 | STK38 | 1.44108904 |
26 | PHKG2 | 1.43794090 |
27 | PHKG1 | 1.43794090 |
28 | RET | 1.40834699 |
29 | CSNK1A1L | 1.37678842 |
30 | LATS2 | 1.36815141 |
31 | TRIM28 | 1.31575133 |
32 | CAMKK2 | 1.26852294 |
33 | SCYL2 | 1.26648625 |
34 | WNK1 | 1.25068920 |
35 | CSNK1G1 | 1.24705366 |
36 | ALK | 1.21713822 |
37 | GRK5 | 1.19113874 |
38 | TAOK1 | 1.16492306 |
39 | PRKCH | 1.15874135 |
40 | MAPK13 | 1.15317350 |
41 | PRKCG | 1.08007040 |
42 | EPHB2 | 1.07931012 |
43 | ARAF | 1.07861394 |
44 | SGK494 | 1.07344409 |
45 | SGK223 | 1.07344409 |
46 | TYRO3 | 1.05798401 |
47 | WNK3 | 1.03870676 |
48 | PNCK | 1.00659669 |
49 | MAP4K2 | 0.99888431 |
50 | CDK19 | 0.98498433 |
51 | PAK3 | 0.98279139 |
52 | EPHA3 | 0.98151688 |
53 | NEK1 | 0.94437799 |
54 | SIK2 | 0.92820925 |
55 | STK11 | 0.92710272 |
56 | CDK14 | 0.91919117 |
57 | RIPK4 | 0.91681290 |
58 | FES | 0.90612079 |
59 | CDK18 | 0.90566632 |
60 | MAP3K1 | 0.90381500 |
61 | TNIK | 0.89633717 |
62 | LIMK1 | 0.88693753 |
63 | CDK15 | 0.88157865 |
64 | CDC42BPA | 0.88091597 |
65 | TSSK6 | 0.88091027 |
66 | PLK2 | 0.84988964 |
67 | DYRK3 | 0.84415235 |
68 | CAMK1G | 0.81963586 |
69 | PKN1 | 0.80955780 |
70 | SGK3 | 0.79475989 |
71 | PINK1 | 0.79077323 |
72 | CSNK1G2 | 0.79009490 |
73 | CDK11A | 0.77024712 |
74 | MKNK2 | 0.75899891 |
75 | DYRK1B | 0.75644493 |
76 | MARK2 | 0.73538693 |
77 | ROCK2 | 0.73317536 |
78 | SGK2 | 0.72870719 |
79 | CAMK2A | 0.70301396 |
80 | MAP3K13 | 0.69441289 |
81 | RIPK1 | 0.69414677 |
82 | TNK2 | 0.69184639 |
83 | CAMK1 | 0.68353015 |
84 | DAPK1 | 0.68314498 |
85 | RPS6KA2 | 0.65977836 |
86 | BRSK1 | 0.58738232 |
87 | MAPK10 | 0.57642591 |
88 | SGK1 | 0.56747704 |
89 | MKNK1 | 0.56122603 |
90 | HIPK2 | 0.55924835 |
91 | RPS6KA3 | 0.55561467 |
92 | PDGFRA | 0.55489236 |
93 | FER | 0.54611338 |
94 | SRPK1 | 0.53109937 |
95 | PRKCZ | 0.52582952 |
96 | TESK1 | 0.52463527 |
97 | ERBB2 | 0.52079020 |
98 | WNK4 | 0.52035463 |
99 | PDPK1 | 0.51997184 |
100 | PLK3 | 0.51702143 |
101 | PDK1 | 0.50997504 |
102 | EPHB1 | 0.49441976 |
103 | BMPR1B | 0.49436496 |
104 | CSNK1E | 0.49003925 |
105 | GRK7 | 0.48897429 |
106 | BCKDK | 0.46791434 |
107 | CSNK1D | 0.46526606 |
108 | DYRK1A | 0.45990622 |
109 | FYN | 0.45326812 |
110 | OXSR1 | 0.44610236 |
111 | PRPF4B | 0.44601450 |
112 | CAMK1D | 0.42351598 |
113 | ROCK1 | 0.42278686 |
114 | MAP2K1 | 0.42193929 |
115 | CASK | 0.41913093 |
116 | FGFR1 | 0.40256546 |
117 | IRAK2 | 0.40256295 |
118 | CAMK2B | 0.39713663 |
119 | PRKDC | 0.39529286 |
120 | CAMK2G | 0.38824863 |
121 | ICK | 0.38483130 |
122 | ADRBK1 | 0.38174534 |
123 | ERBB3 | 0.36541397 |
124 | CAMK4 | 0.36526405 |
125 | PTK2 | 0.36501327 |
126 | CAMK2D | 0.36362648 |
127 | CSNK1A1 | 0.35661388 |
128 | BCR | 0.34842597 |
129 | PRKAA1 | 0.34558930 |
130 | SIK3 | 0.34510606 |
131 | PRKCE | 0.33488568 |
132 | PRKCB | 0.33476111 |
133 | CDC7 | 0.32522020 |
134 | PRKACA | 0.31632434 |
135 | MAPK9 | 0.31607347 |
136 | RPS6KA4 | 0.31242025 |
137 | MAP3K5 | 0.30455787 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 3.30281782 |
2 | Nicotine addiction_Homo sapiens_hsa05033 | 2.96029278 |
3 | GABAergic synapse_Homo sapiens_hsa04727 | 2.75895575 |
4 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 2.68296342 |
5 | Olfactory transduction_Homo sapiens_hsa04740 | 2.58793708 |
6 | Circadian entrainment_Homo sapiens_hsa04713 | 2.42687904 |
7 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 2.30058154 |
8 | Morphine addiction_Homo sapiens_hsa05032 | 2.27413720 |
9 | Insulin secretion_Homo sapiens_hsa04911 | 2.20561581 |
10 | Long-term potentiation_Homo sapiens_hsa04720 | 2.19301307 |
11 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 2.18605576 |
12 | Amphetamine addiction_Homo sapiens_hsa05031 | 2.15861840 |
13 | Glutamatergic synapse_Homo sapiens_hsa04724 | 2.15796982 |
14 | Dopaminergic synapse_Homo sapiens_hsa04728 | 2.14341707 |
15 | Cocaine addiction_Homo sapiens_hsa05030 | 1.94583642 |
16 | Salivary secretion_Homo sapiens_hsa04970 | 1.89113189 |
17 | Cholinergic synapse_Homo sapiens_hsa04725 | 1.84784599 |
18 | Gastric acid secretion_Homo sapiens_hsa04971 | 1.79799462 |
19 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 1.70853934 |
20 | Taste transduction_Homo sapiens_hsa04742 | 1.67663520 |
21 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 1.65668897 |
22 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 1.54280018 |
23 | Renin secretion_Homo sapiens_hsa04924 | 1.54004485 |
24 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.51919853 |
25 | Long-term depression_Homo sapiens_hsa04730 | 1.50514595 |
26 | Serotonergic synapse_Homo sapiens_hsa04726 | 1.48927369 |
27 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 1.46677056 |
28 | Gap junction_Homo sapiens_hsa04540 | 1.42251858 |
29 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 1.42037414 |
30 | GnRH signaling pathway_Homo sapiens_hsa04912 | 1.40092559 |
31 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 1.36835505 |
32 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.34626943 |
33 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 1.33197841 |
34 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.32401587 |
35 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 1.28861149 |
36 | Basal cell carcinoma_Homo sapiens_hsa05217 | 1.26867020 |
37 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 1.23833419 |
38 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.23259168 |
39 | Hippo signaling pathway_Homo sapiens_hsa04390 | 1.21586152 |
40 | Calcium signaling pathway_Homo sapiens_hsa04020 | 1.19828910 |
41 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 1.18891695 |
42 | cAMP signaling pathway_Homo sapiens_hsa04024 | 1.18578301 |
43 | Glioma_Homo sapiens_hsa05214 | 1.12458427 |
44 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 1.07899431 |
45 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 1.07835832 |
46 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 1.06779230 |
47 | Axon guidance_Homo sapiens_hsa04360 | 1.03706297 |
48 | Melanogenesis_Homo sapiens_hsa04916 | 1.03389163 |
49 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 1.03338953 |
50 | ErbB signaling pathway_Homo sapiens_hsa04012 | 1.00379242 |
51 | Oocyte meiosis_Homo sapiens_hsa04114 | 1.00365164 |
52 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 1.00111407 |
53 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.98505097 |
54 | Phototransduction_Homo sapiens_hsa04744 | 0.97924836 |
55 | Parkinsons disease_Homo sapiens_hsa05012 | 0.97008006 |
56 | Protein export_Homo sapiens_hsa03060 | 0.94162639 |
57 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.93184098 |
58 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.91399526 |
59 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.88953130 |
60 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.88801312 |
61 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.88453167 |
62 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.87859977 |
63 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.87071786 |
64 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.87026693 |
65 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.86929920 |
66 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.85756993 |
67 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.81069790 |
68 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 0.79043790 |
69 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.78360695 |
70 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 0.76917706 |
71 | Prion diseases_Homo sapiens_hsa05020 | 0.75078017 |
72 | Alzheimers disease_Homo sapiens_hsa05010 | 0.74918651 |
73 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.73012139 |
74 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.72779792 |
75 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.72493820 |
76 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.71716795 |
77 | Tight junction_Homo sapiens_hsa04530 | 0.71346645 |
78 | Bile secretion_Homo sapiens_hsa04976 | 0.70261212 |
79 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.70152934 |
80 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.69756611 |
81 | Alcoholism_Homo sapiens_hsa05034 | 0.68792447 |
82 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.68503024 |
83 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.68205885 |
84 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.67839544 |
85 | Huntingtons disease_Homo sapiens_hsa05016 | 0.64141371 |
86 | Endocytosis_Homo sapiens_hsa04144 | 0.64046075 |
87 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.63508329 |
88 | Endometrial cancer_Homo sapiens_hsa05213 | 0.63378031 |
89 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.62948464 |
90 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.62245320 |
91 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.62004183 |
92 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.60809995 |
93 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.59840487 |
94 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.59564118 |
95 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.57365840 |
96 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.55487978 |
97 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.53740178 |
98 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.53649593 |
99 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.53447896 |
100 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.52505699 |
101 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.52065284 |
102 | Adherens junction_Homo sapiens_hsa04520 | 0.52046553 |
103 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.50341596 |
104 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.48398815 |
105 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.47789879 |
106 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.47318191 |
107 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.46964070 |
108 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 0.46064326 |
109 | Circadian rhythm_Homo sapiens_hsa04710 | 0.45296012 |
110 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.45240073 |
111 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.44075260 |
112 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.42543380 |
113 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.42321575 |
114 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.41648494 |
115 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.41591654 |
116 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.41424473 |
117 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.41345841 |
118 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.40045377 |
119 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.39347417 |
120 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 0.39071668 |
121 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.38250264 |
122 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.37255482 |
123 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.37186416 |
124 | Colorectal cancer_Homo sapiens_hsa05210 | 0.36256568 |
125 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.35922234 |
126 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.35720150 |
127 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.34714007 |
128 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.33470514 |
129 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 0.32970205 |
130 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.32937054 |
131 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.30553974 |
132 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.28791336 |
133 | Thyroid cancer_Homo sapiens_hsa05216 | 0.28551170 |