Rank | Gene Set | Z-score |
---|---|---|
1 | chondrocyte proliferation (GO:0035988) | 5.57291808 |
2 | collagen fibril organization (GO:0030199) | 5.28280232 |
3 | cell adhesion mediated by integrin (GO:0033627) | 5.25760821 |
4 | endodermal cell differentiation (GO:0035987) | 4.95872217 |
5 | plasma membrane repair (GO:0001778) | 4.73112984 |
6 | protein heterotrimerization (GO:0070208) | 4.70195546 |
7 | wound healing, spreading of epidermal cells (GO:0035313) | 4.49582620 |
8 | sequestering of extracellular ligand from receptor (GO:0035581) | 4.42459575 |
9 | positive regulation of endothelial cell apoptotic process (GO:2000353) | 4.37113615 |
10 | regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547) | 4.35661764 |
11 | negative regulation of fatty acid transport (GO:2000192) | 4.30022295 |
12 | skin morphogenesis (GO:0043589) | 4.22587563 |
13 | basement membrane organization (GO:0071711) | 3.99663242 |
14 | endocardial cushion development (GO:0003197) | 3.95811415 |
15 | hippo signaling (GO:0035329) | 3.91682221 |
16 | retina vasculature morphogenesis in camera-type eye (GO:0061299) | 3.83261636 |
17 | neuron projection extension involved in neuron projection guidance (GO:1902284) | 3.82449447 |
18 | axon extension involved in axon guidance (GO:0048846) | 3.82449447 |
19 | nuclear pore complex assembly (GO:0051292) | 3.80084848 |
20 | vascular endothelial growth factor signaling pathway (GO:0038084) | 3.75188142 |
21 | wound healing, spreading of cells (GO:0044319) | 3.68526620 |
22 | regulation of vascular endothelial growth factor signaling pathway (GO:1900746) | 3.64942449 |
23 | apoptotic cell clearance (GO:0043277) | 3.63945780 |
24 | cell-substrate junction assembly (GO:0007044) | 3.62759865 |
25 | regulation of tight junction assembly (GO:2000810) | 3.62368032 |
26 | planar cell polarity pathway involved in neural tube closure (GO:0090179) | 3.61771629 |
27 | cell migration involved in sprouting angiogenesis (GO:0002042) | 3.60043107 |
28 | glomerular basement membrane development (GO:0032836) | 3.58454571 |
29 | bone trabecula formation (GO:0060346) | 3.58253226 |
30 | substrate adhesion-dependent cell spreading (GO:0034446) | 3.47991478 |
31 | stress fiber assembly (GO:0043149) | 3.43297680 |
32 | collagen metabolic process (GO:0032963) | 3.38350584 |
33 | * epithelial cell-cell adhesion (GO:0090136) | 3.36903805 |
34 | regulation of establishment of planar polarity involved in neural tube closure (GO:0090178) | 3.36698820 |
35 | regulation of transforming growth factor beta2 production (GO:0032909) | 3.32661853 |
36 | collagen catabolic process (GO:0030574) | 3.28126657 |
37 | renal filtration (GO:0097205) | 3.27762608 |
38 | COPI coating of Golgi vesicle (GO:0048205) | 3.25952701 |
39 | Golgi transport vesicle coating (GO:0048200) | 3.25952701 |
40 | regulation of SMAD protein import into nucleus (GO:0060390) | 3.24875673 |
41 | extracellular fibril organization (GO:0043206) | 3.23061020 |
42 | hypotonic response (GO:0006971) | 3.21324170 |
43 | fibroblast migration (GO:0010761) | 3.20614220 |
44 | mesodermal cell differentiation (GO:0048333) | 3.20134199 |
45 | multicellular organismal macromolecule metabolic process (GO:0044259) | 3.19502947 |
46 | insulin-like growth factor receptor signaling pathway (GO:0048009) | 3.17706748 |
47 | extracellular matrix disassembly (GO:0022617) | 3.16695169 |
48 | muscle cell migration (GO:0014812) | 3.14028529 |
49 | negative regulation of cardiac muscle cell apoptotic process (GO:0010667) | 3.11760456 |
50 | nuclear pore organization (GO:0006999) | 3.11386056 |
51 | blood vessel endothelial cell migration (GO:0043534) | 3.11024267 |
52 | paraxial mesoderm development (GO:0048339) | 3.10889162 |
53 | mesenchymal-epithelial cell signaling (GO:0060638) | 3.10058595 |
54 | positive regulation of receptor recycling (GO:0001921) | 3.08774248 |
55 | endothelial cell morphogenesis (GO:0001886) | 3.07911777 |
56 | * platelet aggregation (GO:0070527) | 3.07752618 |
57 | protein localization to endosome (GO:0036010) | 3.07001573 |
58 | notochord development (GO:0030903) | 3.04445928 |
59 | cartilage development involved in endochondral bone morphogenesis (GO:0060351) | 3.04249021 |
60 | regulation of hippo signaling (GO:0035330) | 3.03773995 |
61 | multicellular organismal catabolic process (GO:0044243) | 3.01975857 |
62 | multicellular organismal metabolic process (GO:0044236) | 3.00863403 |
63 | positive regulation of catenin import into nucleus (GO:0035413) | 2.98810634 |
64 | metanephric mesenchyme development (GO:0072075) | 2.98606612 |
65 | cardiac myofibril assembly (GO:0055003) | 2.97129045 |
66 | positive regulation of blood vessel endothelial cell migration (GO:0043536) | 2.97079453 |
67 | cell-substrate adherens junction assembly (GO:0007045) | 2.96409490 |
68 | focal adhesion assembly (GO:0048041) | 2.96409490 |
69 | * adherens junction assembly (GO:0034333) | 2.96230791 |
70 | craniofacial suture morphogenesis (GO:0097094) | 2.94420965 |
71 | positive regulation of epithelial to mesenchymal transition (GO:0010718) | 2.92680104 |
72 | negative regulation of chondrocyte differentiation (GO:0032331) | 2.92527720 |
73 | negative regulation of smooth muscle cell migration (GO:0014912) | 2.91425392 |
74 | positive regulation of SMAD protein import into nucleus (GO:0060391) | 2.89097114 |
75 | negative regulation of fibroblast apoptotic process (GO:2000270) | 2.88574636 |
76 | sarcomere organization (GO:0045214) | 2.87885570 |
77 | cytoskeletal anchoring at plasma membrane (GO:0007016) | 2.87880866 |
78 | cellular response to interferon-alpha (GO:0035457) | 2.87815869 |
79 | kidney mesenchyme development (GO:0072074) | 2.87254608 |
80 | cellular response to vitamin D (GO:0071305) | 2.85155710 |
81 | glomerular filtration (GO:0003094) | 2.84691713 |
82 | cellular response to vitamin (GO:0071295) | 2.84506335 |
83 | glomerular visceral epithelial cell development (GO:0072015) | 2.84044180 |
84 | hemidesmosome assembly (GO:0031581) | 2.83098023 |
85 | positive regulation of osteoblast proliferation (GO:0033690) | 2.83022005 |
86 | polarized epithelial cell differentiation (GO:0030859) | 2.81851690 |
87 | atrioventricular valve morphogenesis (GO:0003181) | 2.81003208 |
88 | branching involved in salivary gland morphogenesis (GO:0060445) | 2.79797774 |
89 | substrate-dependent cell migration (GO:0006929) | 2.79519257 |
90 | positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S tr | 2.79196721 |
91 | barbed-end actin filament capping (GO:0051016) | 2.78884433 |
92 | fibril organization (GO:0097435) | 2.78135985 |
93 | response to fluid shear stress (GO:0034405) | 2.76547422 |
94 | regulation of cardioblast differentiation (GO:0051890) | 2.75384067 |
95 | positive regulation of macrophage activation (GO:0043032) | 2.74739346 |
96 | regulation of early endosome to late endosome transport (GO:2000641) | 2.73730719 |
97 | cellular response to vascular endothelial growth factor stimulus (GO:0035924) | 2.73075828 |
98 | negative regulation of homotypic cell-cell adhesion (GO:0034111) | 2.69135120 |
99 | germ cell migration (GO:0008354) | 2.69013323 |
100 | peptidyl-proline hydroxylation (GO:0019511) | 2.68641461 |
101 | ventricular cardiac muscle cell development (GO:0055015) | 2.67961550 |
102 | regulation of low-density lipoprotein particle receptor biosynthetic process (GO:0045714) | 2.67693291 |
103 | protein hydroxylation (GO:0018126) | 2.66941142 |
104 | positive regulation of Rho protein signal transduction (GO:0035025) | 2.66825045 |
105 | heparan sulfate proteoglycan biosynthetic process (GO:0015012) | 2.66556305 |
106 | convergent extension (GO:0060026) | 2.65858710 |
107 | regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition | 2.65765731 |
108 | lymphangiogenesis (GO:0001946) | 2.64229866 |
109 | mRNA transcription (GO:0009299) | 2.63791752 |
110 | regulation of integrin-mediated signaling pathway (GO:2001044) | 2.62608213 |
111 | epoxygenase P450 pathway (GO:0019373) | 2.62434122 |
112 | gap junction assembly (GO:0016264) | 2.59733723 |
113 | dermatan sulfate biosynthetic process (GO:0030208) | 2.59483251 |
114 | extracellular matrix organization (GO:0030198) | 2.58692173 |
115 | * platelet degranulation (GO:0002576) | 2.58287440 |
116 | extracellular structure organization (GO:0043062) | 2.57944650 |
117 | actomyosin structure organization (GO:0031032) | 2.57784284 |
118 | * protein localization to cell surface (GO:0034394) | 2.57100321 |
119 | positive regulation of transforming growth factor beta receptor signaling pathway (GO:0030511) | 2.56625878 |
120 | * cell-substrate adhesion (GO:0031589) | 2.56494228 |
121 | heterochromatin organization (GO:0070828) | 2.56226198 |
122 | regulation of cell fate specification (GO:0042659) | 2.55952835 |
123 | atrial septum morphogenesis (GO:0060413) | 2.55781376 |
124 | NLS-bearing protein import into nucleus (GO:0006607) | 2.55039555 |
125 | cellular protein complex localization (GO:0034629) | 2.54766108 |
126 | chondrocyte development (GO:0002063) | 2.54568250 |
127 | pore complex assembly (GO:0046931) | 2.54304961 |
128 | extracellular matrix assembly (GO:0085029) | 2.52888293 |
129 | anterior/posterior axis specification, embryo (GO:0008595) | 2.52224648 |
130 | dichotomous subdivision of an epithelial terminal unit (GO:0060600) | 2.51884426 |
131 | * cell junction assembly (GO:0034329) | 2.50725838 |
132 | * cell-matrix adhesion (GO:0007160) | 2.50571009 |
133 | negative regulation of focal adhesion assembly (GO:0051895) | 2.50523280 |
134 | negative regulation of cell junction assembly (GO:1901889) | 2.50523280 |
135 | negative regulation of adherens junction organization (GO:1903392) | 2.50523280 |
136 | protein complex localization (GO:0031503) | 2.50513546 |
137 | regulation of branching involved in salivary gland morphogenesis (GO:0060693) | 2.50295304 |
138 | SMAD protein complex assembly (GO:0007183) | 2.48732491 |
139 | Wnt signaling pathway, planar cell polarity pathway (GO:0060071) | 2.48243483 |
140 | regulation of posttranscriptional gene silencing (GO:0060147) | 2.47220763 |
141 | regulation of gene silencing by miRNA (GO:0060964) | 2.47220763 |
142 | regulation of gene silencing by RNA (GO:0060966) | 2.47220763 |
143 | cell migration involved in heart development (GO:0060973) | 2.46264656 |
144 | regulation of integrin activation (GO:0033623) | 2.45730672 |
145 | negative regulation of protein localization to plasma membrane (GO:1903077) | 2.44326268 |
146 | thrombin receptor signaling pathway (GO:0070493) | 2.42276751 |
147 | establishment or maintenance of epithelial cell apical/basal polarity (GO:0045197) | 2.42230944 |
148 | phagocytosis, engulfment (GO:0006911) | 2.41040680 |
149 | cortical actin cytoskeleton organization (GO:0030866) | 2.40550173 |
Rank | Gene Set | Z-score |
---|---|---|
1 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 5.45274317 |
2 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 5.25350176 |
3 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 4.67107466 |
4 | E2F7_22180533_ChIP-Seq_HELA_Human | 4.18882730 |
5 | * NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 3.61531548 |
6 | * CLOCK_20551151_ChIP-Seq_293T_Human | 3.31387142 |
7 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 3.00591478 |
8 | RUNX2_24764292_ChIP-Seq_MC3T3_Mouse | 2.91116789 |
9 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 2.75919093 |
10 | * TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 2.58998523 |
11 | PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse | 2.56800868 |
12 | HIF1A_21447827_ChIP-Seq_MCF-7_Human | 2.50596502 |
13 | SMAD4_19686287_ChIP-ChIP_HaCaT_Human | 2.39169960 |
14 | EP300_21415370_ChIP-Seq_HL-1_Mouse | 2.35706958 |
15 | * CJUN_26792858_Chip-Seq_BT549_Human | 2.32499209 |
16 | WT1_19549856_ChIP-ChIP_CCG9911_Human | 2.30028872 |
17 | CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse | 2.28464159 |
18 | * BRD4_25478319_ChIP-Seq_HGPS_Human | 2.18754386 |
19 | EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse | 2.17646417 |
20 | CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse | 2.08595646 |
21 | * SMAD2_18955504_ChIP-ChIP_HaCaT_Human | 2.06353386 |
22 | * SMAD3_18955504_ChIP-ChIP_HaCaT_Human | 2.06353386 |
23 | PPAR_26484153_Chip-Seq_NCI-H1993_Human | 2.04235246 |
24 | * ESR1_22446102_ChIP-Seq_UTERUS_Mouse | 2.02296956 |
25 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 2.01543716 |
26 | ESR1_21235772_ChIP-Seq_MCF-7_Human | 1.98619778 |
27 | WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse | 1.96348415 |
28 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 1.95641178 |
29 | NANOG_18700969_ChIP-ChIP_MESCs_Mouse | 1.93407435 |
30 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 1.92794248 |
31 | * SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse | 1.78616877 |
32 | KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.77940805 |
33 | FOXO3_23340844_ChIP-Seq_DLD1_Human | 1.74272867 |
34 | SALL4_18804426_ChIP-ChIP_XEN_Mouse | 1.73741117 |
35 | TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.73153354 |
36 | ATF3_27146783_Chip-Seq_COLON_Human | 1.69241485 |
37 | KLF5_18264089_ChIP-ChIP_MESCs_Mouse | 1.66172204 |
38 | KLF4_18264089_ChIP-ChIP_MESCs_Mouse | 1.66172204 |
39 | KLF2_18264089_ChIP-ChIP_MESCs_Mouse | 1.66172204 |
40 | * P300_27058665_Chip-Seq_ZR-75-30cells_Human | 1.64761599 |
41 | NFE2L2_20460467_ChIP-Seq_MEFs_Mouse | 1.63961993 |
42 | NRF2_20460467_ChIP-Seq_MEFs_Mouse | 1.63961993 |
43 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 1.61565197 |
44 | TP53_16413492_ChIP-PET_HCT116_Human | 1.61229992 |
45 | TBX20_22080862_ChIP-Seq_HEART_Mouse | 1.60779629 |
46 | TBX20_22328084_ChIP-Seq_HEART_Mouse | 1.60779629 |
47 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 1.58871614 |
48 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.57729253 |
49 | ATF3_23680149_ChIP-Seq_GBM1-GSC_Human | 1.50773620 |
50 | JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.50625789 |
51 | UBF1/2_26484160_Chip-Seq_HMECs_Human | 1.49951137 |
52 | HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse | 1.48127427 |
53 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.46871331 |
54 | * SOX9_24532713_ChIP-Seq_HFSC_Mouse | 1.43992031 |
55 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 1.43513958 |
56 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.43162608 |
57 | PRDM5_23873026_ChIP-Seq_MEFs_Mouse | 1.42780906 |
58 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 1.41138135 |
59 | * KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 1.40835034 |
60 | * MEF2A_21415370_ChIP-Seq_HL-1_Mouse | 1.39649286 |
61 | TP53_22127205_ChIP-Seq_IMR90_Human | 1.38101637 |
62 | * NKX2-5_21415370_ChIP-Seq_HL-1_Mouse | 1.37690211 |
63 | ZIC3_20872845_ChIP-ChIP_MESCs_Mouse | 1.36649458 |
64 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 1.35224790 |
65 | JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.32184254 |
66 | SOX2_20726797_ChIP-Seq_SW620_Human | 1.31299011 |
67 | * MYB_21317192_ChIP-Seq_ERMYB_Mouse | 1.30939930 |
68 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 1.30655062 |
69 | TCF3_18692474_ChIP-Seq_MESCs_Mouse | 1.30516149 |
70 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.30216692 |
71 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.29834792 |
72 | TCF3_18467660_ChIP-ChIP_MESCs_Mouse | 1.29759339 |
73 | * RACK7_27058665_Chip-Seq_MCF-7_Human | 1.27771329 |
74 | * KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.27392796 |
75 | SMC1_22415368_ChIP-Seq_MEFs_Mouse | 1.27097258 |
76 | AR_21909140_ChIP-Seq_LNCAP_Human | 1.26956007 |
77 | NACC1_18358816_ChIP-ChIP_MESCs_Mouse | 1.25679888 |
78 | ZFP281_18358816_ChIP-ChIP_MESCs_Mouse | 1.24702790 |
79 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.23438011 |
80 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.22238763 |
81 | ZNF217_24962896_ChIP-Seq_MCF-7_Human | 1.21914710 |
82 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 1.21581979 |
83 | KLF4_18555785_ChIP-Seq_MESCs_Mouse | 1.20955346 |
84 | ZNF263_19887448_ChIP-Seq_K562_Human | 1.19755461 |
85 | HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse | 1.19208597 |
86 | * KDM2B_26808549_Chip-Seq_SUP-B15_Human | 1.18877033 |
87 | SMAD3_22036565_ChIP-Seq_ESCs_Mouse | 1.18695276 |
88 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 1.18051182 |
89 | * CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.17517230 |
90 | TP53_23651856_ChIP-Seq_MEFs_Mouse | 1.17429976 |
91 | DMRT1_23473982_ChIP-Seq_TESTES_Mouse | 1.17195429 |
92 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 1.16215944 |
93 | FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human | 1.14028542 |
94 | ZFP281_18757296_ChIP-ChIP_E14_Mouse | 1.13936298 |
95 | SALL4_18804426_ChIP-ChIP_MESCs_Mouse | 1.13908662 |
96 | TP53_18474530_ChIP-ChIP_U2OS_Human | 1.13606063 |
97 | ISL1_27105846_Chip-Seq_CPCs_Mouse | 1.13125014 |
98 | TCF3_18692474_ChIP-Seq_MEFs_Mouse | 1.12274328 |
99 | * ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.10634597 |
100 | PPARG_20176806_ChIP-Seq_3T3-L1_Mouse | 1.10178200 |
101 | * EOMES_20176728_ChIP-ChIP_TSCs_Mouse | 1.09267531 |
102 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.08844440 |
103 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.08453542 |
104 | * TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 1.08292765 |
105 | * GATA4_21415370_ChIP-Seq_HL-1_Mouse | 1.07827379 |
106 | UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human | 1.05759242 |
107 | GATA1_19941826_ChIP-Seq_K562_Human | 1.05429293 |
108 | ZFP281_27345836_Chip-Seq_ESCs_Mouse | 1.04364352 |
109 | SOX17_20123909_ChIP-Seq_XEN_Mouse | 1.04274192 |
110 | ZNF652_21678463_ChIP-ChIP_ZR75-1_Human | 1.03581029 |
111 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.03027141 |
112 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 1.02899005 |
113 | KDM2B_26808549_Chip-Seq_DND41_Human | 1.02458271 |
114 | * FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.01834730 |
115 | CTNNB1_20460455_ChIP-Seq_HCT116_Human | 1.00975687 |
116 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 0.99770562 |
117 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 0.99692555 |
118 | * KLF5_25053715_ChIP-Seq_YYC3_Human | 0.98032593 |
119 | TP53_20018659_ChIP-ChIP_R1E_Mouse | 0.97585268 |
120 | RUNX1_27514584_Chip-Seq_MCF-7_Human | 0.97518171 |
121 | NFIB_24661679_ChIP-Seq_LUNG_Mouse | 0.97386962 |
122 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 0.97373757 |
123 | KLF4_18358816_ChIP-ChIP_MESCs_Mouse | 0.96354250 |
124 | NANOG_16153702_ChIP-ChIP_HESCs_Human | 0.96021448 |
125 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 0.95972817 |
126 | SOX2_27498859_Chip-Seq_STOMACH_Mouse | 0.95112671 |
127 | NANOG_18692474_ChIP-Seq_MEFs_Mouse | 0.93383641 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0008438_abnormal_cutaneous_collagen | 6.51365466 |
2 | MP0003705_abnormal_hypodermis_morpholog | 4.20246968 |
3 | MP0005275_abnormal_skin_tensile | 4.11827338 |
4 | MP0003279_aneurysm | 3.52324095 |
5 | MP0005503_abnormal_tendon_morphology | 3.37027333 |
6 | MP0005623_abnormal_meninges_morphology | 3.25483587 |
7 | MP0004272_abnormal_basement_membrane | 3.17284989 |
8 | MP0003566_abnormal_cell_adhesion | 2.95889201 |
9 | MP0010352_gastrointestinal_tract_polyps | 2.89959957 |
10 | MP0001958_emphysema | 2.78653856 |
11 | MP0009384_cardiac_valve_regurgitation | 2.54515462 |
12 | MP0006054_spinal_hemorrhage | 2.03058161 |
13 | MP0005023_abnormal_wound_healing | 1.98734475 |
14 | * MP0003091_abnormal_cell_migration | 1.91829442 |
15 | MP0004084_abnormal_cardiac_muscle | 1.88283383 |
16 | MP0000733_abnormal_muscle_development | 1.81369874 |
17 | MP0010030_abnormal_orbit_morphology | 1.81185277 |
18 | MP0005464_abnormal_platelet_physiology | 1.71769395 |
19 | MP0000767_abnormal_smooth_muscle | 1.65656950 |
20 | MP0005508_abnormal_skeleton_morphology | 1.63308614 |
21 | MP0002295_abnormal_pulmonary_circulatio | 1.58669368 |
22 | MP0002060_abnormal_skin_morphology | 1.58205196 |
23 | MP0009053_abnormal_anal_canal | 1.56122939 |
24 | MP0003385_abnormal_body_wall | 1.52246809 |
25 | MP0005257_abnormal_intraocular_pressure | 1.49926243 |
26 | MP0000750_abnormal_muscle_regeneration | 1.48436557 |
27 | MP0010368_abnormal_lymphatic_system | 1.47401072 |
28 | MP0000751_myopathy | 1.45824683 |
29 | MP0002877_abnormal_melanocyte_morpholog | 1.43281115 |
30 | MP0003045_fibrosis | 1.41169619 |
31 | MP0002254_reproductive_system_inflammat | 1.37044059 |
32 | MP0005076_abnormal_cell_differentiation | 1.34770300 |
33 | MP0008004_abnormal_stomach_pH | 1.33063079 |
34 | MP0006138_congestive_heart_failure | 1.29701072 |
35 | MP0002896_abnormal_bone_mineralization | 1.29048998 |
36 | MP0003300_gastrointestinal_ulcer | 1.28087182 |
37 | MP0001299_abnormal_eye_distance/ | 1.27962971 |
38 | MP0003950_abnormal_plasma_membrane | 1.27736502 |
39 | MP0002108_abnormal_muscle_morphology | 1.24867412 |
40 | MP0000537_abnormal_urethra_morphology | 1.24709030 |
41 | MP0000013_abnormal_adipose_tissue | 1.24638984 |
42 | MP0003941_abnormal_skin_development | 1.24299157 |
43 | MP0001243_abnormal_dermal_layer | 1.23314126 |
44 | * MP0004087_abnormal_muscle_fiber | 1.23264576 |
45 | MP0009250_abnormal_appendicular_skeleto | 1.22451723 |
46 | MP0001348_abnormal_lacrimal_gland | 1.14372617 |
47 | MP0000762_abnormal_tongue_morphology | 1.13622101 |
48 | MP0005330_cardiomyopathy | 1.13284407 |
49 | MP0000749_muscle_degeneration | 1.13227880 |
50 | MP0004957_abnormal_blastocyst_morpholog | 1.13058855 |
51 | * MP0010630_abnormal_cardiac_muscle | 1.12449352 |
52 | MP0003115_abnormal_respiratory_system | 1.12288226 |
53 | MP0002168_other_aberrant_phenotype | 1.10745745 |
54 | MP0001661_extended_life_span | 1.10546510 |
55 | MP0000428_abnormal_craniofacial_morphol | 1.10231882 |
56 | MP0002128_abnormal_blood_circulation | 1.09700997 |
57 | MP0000534_abnormal_ureter_morphology | 1.06658838 |
58 | MP0002282_abnormal_trachea_morphology | 1.05828554 |
59 | * MP0001730_embryonic_growth_arrest | 1.04129710 |
60 | MP0003942_abnormal_urinary_system | 1.03517164 |
61 | MP0001542_abnormal_bone_strength | 1.02785089 |
62 | MP0001879_abnormal_lymphatic_vessel | 1.01839756 |
63 | * MP0001614_abnormal_blood_vessel | 1.00194577 |
64 | * MP0002925_abnormal_cardiovascular_devel | 1.00193357 |
65 | MP0008775_abnormal_heart_ventricle | 0.98626479 |
66 | MP0005409_darkened_coat_color | 0.97845762 |
67 | MP0003828_pulmonary_edema | 0.96194282 |
68 | MP0000858_altered_metastatic_potential | 0.95058306 |
69 | MP0000003_abnormal_adipose_tissue | 0.94975532 |
70 | MP0003283_abnormal_digestive_organ | 0.94908766 |
71 | * MP0002085_abnormal_embryonic_tissue | 0.94440576 |
72 | MP0009697_abnormal_copulation | 0.94244053 |
73 | * MP0008932_abnormal_embryonic_tissue | 0.94207853 |
74 | MP0004510_myositis | 0.93858312 |
75 | * MP0002084_abnormal_developmental_patter | 0.93526108 |
76 | * MP0003984_embryonic_growth_retardation | 0.93058145 |
77 | * MP0001672_abnormal_embryogenesis/_devel | 0.92805367 |
78 | * MP0005380_embryogenesis_phenotype | 0.92805367 |
79 | MP0009672_abnormal_birth_weight | 0.92621597 |
80 | MP0005501_abnormal_skin_physiology | 0.92559518 |
81 | MP0002837_dystrophic_cardiac_calcinosis | 0.92345673 |
82 | MP0005595_abnormal_vascular_smooth | 0.92165992 |
83 | MP0004858_abnormal_nervous_system | 0.91747896 |
84 | MP0004233_abnormal_muscle_weight | 0.91464466 |
85 | MP0000163_abnormal_cartilage_morphology | 0.91203778 |
86 | MP0004036_abnormal_muscle_relaxation | 0.90748592 |
87 | MP0005390_skeleton_phenotype | 0.89789887 |
88 | MP0001915_intracranial_hemorrhage | 0.88961086 |
89 | MP0002932_abnormal_joint_morphology | 0.88783888 |
90 | MP0001544_abnormal_cardiovascular_syste | 0.87819380 |
91 | MP0005385_cardiovascular_system_phenoty | 0.87819380 |
92 | MP0002115_abnormal_skeleton_extremities | 0.87655216 |
93 | MP0003755_abnormal_palate_morphology | 0.87527167 |
94 | * MP0005621_abnormal_cell_physiology | 0.86836658 |
95 | * MP0002088_abnormal_embryonic_growth/wei | 0.86674674 |
96 | MP0000579_abnormal_nail_morphology | 0.86311870 |
97 | MP0003111_abnormal_nucleus_morphology | 0.86197831 |
98 | MP0000759_abnormal_skeletal_muscle | 0.86028126 |
99 | MP0004197_abnormal_fetal_growth/weight/ | 0.84794611 |
100 | MP0003453_abnormal_keratinocyte_physiol | 0.84066762 |
101 | MP0002113_abnormal_skeleton_development | 0.83250524 |
102 | * MP0003935_abnormal_craniofacial_develop | 0.82470192 |
103 | MP0002796_impaired_skin_barrier | 0.80458267 |
104 | * MP0000266_abnormal_heart_morphology | 0.80393585 |
105 | * MP0002972_abnormal_cardiac_muscle | 0.80018173 |
106 | MP0000516_abnormal_urinary_system | 0.79473774 |
107 | MP0005367_renal/urinary_system_phenotyp | 0.79473774 |
108 | MP0005165_increased_susceptibility_to | 0.79387331 |
109 | * MP0002080_prenatal_lethality | 0.79315717 |
110 | MP0000350_abnormal_cell_proliferation | 0.78941453 |
111 | MP0004134_abnormal_chest_morphology | 0.78240512 |
112 | MP0000467_abnormal_esophagus_morphology | 0.77673080 |
113 | MP0002697_abnormal_eye_size | 0.77620111 |
114 | MP0004185_abnormal_adipocyte_glucose | 0.77518003 |
115 | MP0005197_abnormal_uvea_morphology | 0.77321613 |
116 | MP0002269_muscular_atrophy | 0.76968331 |
117 | MP0005375_adipose_tissue_phenotype | 0.76287671 |
118 | * MP0000432_abnormal_head_morphology | 0.75915685 |
119 | * MP0005620_abnormal_muscle_contractility | 0.75796310 |
120 | MP0009780_abnormal_chondrocyte_physiolo | 0.74792351 |
121 | MP0009278_abnormal_bone_marrow | 0.73525162 |
122 | MP0001849_ear_inflammation | 0.72347769 |
123 | MP0001175_abnormal_lung_morphology | 0.71353514 |
124 | * MP0003937_abnormal_limbs/digits/tail_de | 0.69770771 |
125 | MP0003567_abnormal_fetal_cardiomyocyte | 0.69390040 |
126 | MP0002089_abnormal_postnatal_growth/wei | 0.69084458 |
127 | MP0002086_abnormal_extraembryonic_tissu | 0.68902678 |
128 | MP0003448_altered_tumor_morphology | 0.68601737 |
129 | MP0000747_muscle_weakness | 0.68349734 |
130 | MP0005369_muscle_phenotype | 0.66886621 |
131 | MP0002933_joint_inflammation | 0.66807335 |
132 | MP0005193_abnormal_anterior_eye | 0.66755014 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Premature rupture of membranes (HP:0001788) | 6.84603046 |
2 | Protrusio acetabuli (HP:0003179) | 6.77814918 |
3 | Aortic dissection (HP:0002647) | 4.67419188 |
4 | Ankle contracture (HP:0006466) | 4.62180932 |
5 | Shallow orbits (HP:0000586) | 4.47529657 |
6 | Cerebral aneurysm (HP:0004944) | 4.13309093 |
7 | Aortic aneurysm (HP:0004942) | 4.13202380 |
8 | Peritonitis (HP:0002586) | 4.03000350 |
9 | Atrophic scars (HP:0001075) | 4.02298038 |
10 | Abnormal platelet volume (HP:0011876) | 3.93935551 |
11 | Cervical subluxation (HP:0003308) | 3.75639066 |
12 | Dilatation of the ascending aorta (HP:0005111) | 3.62796314 |
13 | Broad metatarsal (HP:0001783) | 3.49219548 |
14 | Increased connective tissue (HP:0009025) | 3.48795110 |
15 | Soft skin (HP:0000977) | 3.47029250 |
16 | Bladder diverticulum (HP:0000015) | 3.38004627 |
17 | Fragile skin (HP:0001030) | 3.34436659 |
18 | Type 1 muscle fiber predominance (HP:0003803) | 3.26926821 |
19 | Abnormality of dentin (HP:0010299) | 3.20193411 |
20 | Mitral valve prolapse (HP:0001634) | 3.18766221 |
21 | Spinal rigidity (HP:0003306) | 3.14023297 |
22 | Menorrhagia (HP:0000132) | 3.12590717 |
23 | Wrist flexion contracture (HP:0001239) | 3.02571080 |
24 | Genu recurvatum (HP:0002816) | 2.95100994 |
25 | Wormian bones (HP:0002645) | 2.94302616 |
26 | Neonatal short-limb short stature (HP:0008921) | 2.84845734 |
27 | Blue sclerae (HP:0000592) | 2.79696208 |
28 | Right ventricular cardiomyopathy (HP:0011663) | 2.78871615 |
29 | Aneurysm (HP:0002617) | 2.66538197 |
30 | Osteolytic defects of the hand bones (HP:0009699) | 2.64527370 |
31 | Osteolytic defects of the phalanges of the hand (HP:0009771) | 2.64527370 |
32 | Short nail (HP:0001799) | 2.60548381 |
33 | Increased density of long bones (HP:0006392) | 2.55304973 |
34 | Bowel diverticulosis (HP:0005222) | 2.54560887 |
35 | Mildly elevated creatine phosphokinase (HP:0008180) | 2.51843153 |
36 | Abnormality of the calcaneus (HP:0008364) | 2.51727423 |
37 | Muscle fiber splitting (HP:0003555) | 2.51542436 |
38 | Scapular winging (HP:0003691) | 2.51003050 |
39 | Radial bowing (HP:0002986) | 2.48782671 |
40 | Vascular tortuosity (HP:0004948) | 2.46244927 |
41 | Increased variability in muscle fiber diameter (HP:0003557) | 2.45535839 |
42 | Difficulty climbing stairs (HP:0003551) | 2.45212424 |
43 | Camptodactyly of toe (HP:0001836) | 2.43868962 |
44 | Biconcave vertebral bodies (HP:0004586) | 2.42811118 |
45 | Follicular hyperkeratosis (HP:0007502) | 2.40284460 |
46 | Lower limb amyotrophy (HP:0007210) | 2.39808604 |
47 | Short 4th metacarpal (HP:0010044) | 2.37978627 |
48 | Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042) | 2.37978627 |
49 | Ulnar bowing (HP:0003031) | 2.36781144 |
50 | Mesomelia (HP:0003027) | 2.31076728 |
51 | Vertebral compression fractures (HP:0002953) | 2.30814333 |
52 | Distal upper limb amyotrophy (HP:0007149) | 2.30647204 |
53 | Upper limb amyotrophy (HP:0009129) | 2.30647204 |
54 | Hyporeflexia of lower limbs (HP:0002600) | 2.28785289 |
55 | Disproportionate tall stature (HP:0001519) | 2.27424038 |
56 | Elbow flexion contracture (HP:0002987) | 2.26714585 |
57 | Infantile muscular hypotonia (HP:0008947) | 2.26328076 |
58 | Tibial bowing (HP:0002982) | 2.26069866 |
59 | Abnormality of skeletal muscle fiber size (HP:0012084) | 2.24867041 |
60 | Abnormality of the acetabulum (HP:0003170) | 2.23776664 |
61 | Round ear (HP:0100830) | 2.20093028 |
62 | Abnormal delivery (HP:0001787) | 2.20049057 |
63 | Broad face (HP:0000283) | 2.19028687 |
64 | Hyperextensible skin (HP:0000974) | 2.18434900 |
65 | Abnormality of oral frenula (HP:0000190) | 2.12399788 |
66 | Bowing of the arm (HP:0006488) | 2.11828887 |
67 | Bowed forearm bones (HP:0003956) | 2.11828887 |
68 | Abnormality of the peritoneum (HP:0002585) | 2.11278810 |
69 | Prolonged bleeding time (HP:0003010) | 2.09700348 |
70 | Spinal cord lesions (HP:0100561) | 2.09646057 |
71 | Syringomyelia (HP:0003396) | 2.09646057 |
72 | Thin bony cortex (HP:0002753) | 2.08398430 |
73 | Knee flexion contracture (HP:0006380) | 2.08088404 |
74 | Distal lower limb muscle weakness (HP:0009053) | 2.07478826 |
75 | Deviation of the hallux (HP:0010051) | 2.07424772 |
76 | Mitral regurgitation (HP:0001653) | 2.04965361 |
77 | Overgrowth (HP:0001548) | 2.04168392 |
78 | Ectopia lentis (HP:0001083) | 2.04112459 |
79 | Buphthalmos (HP:0000557) | 2.03998469 |
80 | Arterial tortuosity (HP:0005116) | 2.03575263 |
81 | Hallux valgus (HP:0001822) | 2.01054049 |
82 | Fused cervical vertebrae (HP:0002949) | 2.00507719 |
83 | Distal lower limb amyotrophy (HP:0008944) | 1.99656036 |
84 | Slender build (HP:0001533) | 1.99333005 |
85 | Abnormality of the 4th metacarpal (HP:0010012) | 1.99300118 |
86 | Wide anterior fontanel (HP:0000260) | 1.99224101 |
87 | Joint laxity (HP:0001388) | 1.99142211 |
88 | Nemaline bodies (HP:0003798) | 1.98968412 |
89 | Muscle fiber cytoplasmatic inclusion bodies (HP:0100303) | 1.97720441 |
90 | Ankyloglossia (HP:0010296) | 1.96586399 |
91 | Joint contractures involving the joints of the feet (HP:0100492) | 1.92551327 |
92 | Flexion contracture of toe (HP:0005830) | 1.92551327 |
93 | Selective tooth agenesis (HP:0001592) | 1.90372162 |
94 | Increased mean platelet volume (HP:0011877) | 1.89540418 |
95 | Tarsal synostosis (HP:0008368) | 1.87912812 |
96 | Broad long bones (HP:0005622) | 1.86006727 |
97 | Absent frontal sinuses (HP:0002688) | 1.85083244 |
98 | Aortic regurgitation (HP:0001659) | 1.81922737 |
99 | Natal tooth (HP:0000695) | 1.81200676 |
100 | Short hallux (HP:0010109) | 1.80817512 |
101 | Bell-shaped thorax (HP:0001591) | 1.80055548 |
102 | Broad ribs (HP:0000885) | 1.76668689 |
103 | Muscle fiber inclusion bodies (HP:0100299) | 1.75146886 |
104 | Myocardial infarction (HP:0001658) | 1.74796864 |
105 | Abnormality of the distal phalanx of the thumb (HP:0009617) | 1.74738242 |
106 | Back pain (HP:0003418) | 1.74676903 |
107 | Persistence of primary teeth (HP:0006335) | 1.73839585 |
108 | Coronal craniosynostosis (HP:0004440) | 1.73789962 |
109 | Hip contracture (HP:0003273) | 1.73493561 |
110 | Vertebral arch anomaly (HP:0008438) | 1.73055482 |
111 | Venous abnormality (HP:0002624) | 1.71729186 |
112 | Femoral bowing (HP:0002980) | 1.71058651 |
113 | Hand muscle atrophy (HP:0009130) | 1.70887682 |
114 | Delayed cranial suture closure (HP:0000270) | 1.70722778 |
115 | Breech presentation (HP:0001623) | 1.70579084 |
116 | Relative macrocephaly (HP:0004482) | 1.69943953 |
117 | Hyperacusis (HP:0010780) | 1.69115589 |
118 | Spondylolisthesis (HP:0003302) | 1.69021641 |
119 | Mitral stenosis (HP:0001718) | 1.68909696 |
120 | Difficulty running (HP:0009046) | 1.68593486 |
121 | Spastic diplegia (HP:0001264) | 1.63609370 |
122 | Abnormality of the umbilical cord (HP:0010881) | 1.61484351 |
123 | Centrally nucleated skeletal muscle fibers (HP:0003687) | 1.61291550 |
124 | Achilles tendon contracture (HP:0001771) | 1.60987342 |
125 | Aortic valve stenosis (HP:0001650) | 1.60917090 |
126 | Aplasia/Hypoplasia of the frontal sinuses (HP:0009119) | 1.60045880 |
127 | Petechiae (HP:0000967) | 1.59290226 |
128 | Limb-girdle muscle weakness (HP:0003325) | 1.58909462 |
129 | Arnold-Chiari malformation (HP:0002308) | 1.58691609 |
130 | Generalized amyotrophy (HP:0003700) | 1.57493075 |
Rank | Gene Set | Z-score |
---|---|---|
1 | TTN | 5.67000527 |
2 | TRIB3 | 3.93949835 |
3 | DDR2 | 3.39884898 |
4 | LATS1 | 3.17701169 |
5 | PDGFRA | 2.91179012 |
6 | PKN2 | 2.79459426 |
7 | EPHA2 | 2.43636668 |
8 | RIPK1 | 2.26114233 |
9 | DMPK | 2.21065736 |
10 | PAK2 | 2.09690860 |
11 | TRPM7 | 2.04395749 |
12 | LATS2 | 2.00068665 |
13 | SIK1 | 1.93385816 |
14 | ERN1 | 1.82598155 |
15 | PTK2 | 1.78247260 |
16 | MYLK | 1.77708911 |
17 | EPHB2 | 1.73777123 |
18 | PTK6 | 1.63248478 |
19 | BMX | 1.63098250 |
20 | EIF2AK1 | 1.62829893 |
21 | SMG1 | 1.61262065 |
22 | CDK12 | 1.59589454 |
23 | LRRK2 | 1.59375496 |
24 | PAK3 | 1.53765830 |
25 | STK3 | 1.48710016 |
26 | PIK3CA | 1.47243303 |
27 | EEF2K | 1.46228813 |
28 | FER | 1.44590981 |
29 | TESK1 | 1.44146060 |
30 | TTK | 1.41375018 |
31 | PAK4 | 1.38568118 |
32 | MET | 1.30243466 |
33 | TGFBR2 | 1.29634854 |
34 | MTOR | 1.24552778 |
35 | PTK2B | 1.21750949 |
36 | LIMK1 | 1.19850527 |
37 | BRSK2 | 1.18362438 |
38 | ILK | 1.16431435 |
39 | STK10 | 1.13845438 |
40 | STK38L | 1.12770980 |
41 | PDGFRB | 1.12545127 |
42 | EPHB1 | 1.12238272 |
43 | ROCK1 | 1.11625632 |
44 | MST4 | 1.10120504 |
45 | FGFR1 | 1.08466189 |
46 | EPHA3 | 1.07457495 |
47 | MAP3K10 | 1.05791455 |
48 | FRK | 1.04217307 |
49 | TSSK6 | 1.01193824 |
50 | CAMK1D | 0.99331654 |
51 | MOS | 0.94679180 |
52 | STK24 | 0.89015038 |
53 | LMTK2 | 0.87937197 |
54 | NUAK1 | 0.86101248 |
55 | STK4 | 0.84865841 |
56 | NEK9 | 0.84303701 |
57 | CDC7 | 0.82558298 |
58 | MELK | 0.81400369 |
59 | PIK3CG | 0.81257506 |
60 | STK38 | 0.81227932 |
61 | PLK3 | 0.77368359 |
62 | TGFBR1 | 0.76092318 |
63 | RPS6KA4 | 0.75084216 |
64 | FLT3 | 0.73995436 |
65 | CDK6 | 0.73856174 |
66 | ERBB3 | 0.71750358 |
67 | RPS6KB2 | 0.71448386 |
68 | SCYL2 | 0.70969529 |
69 | PNCK | 0.70724058 |
70 | MAP3K3 | 0.70318672 |
71 | ROCK2 | 0.69097926 |
72 | MAP3K6 | 0.68469817 |
73 | MAP2K1 | 0.68195979 |
74 | CDC42BPA | 0.68043259 |
75 | MAP2K3 | 0.67631032 |
76 | MAP3K8 | 0.65285310 |
77 | MAPKAPK3 | 0.65155722 |
78 | KDR | 0.64497784 |
79 | PRKG2 | 0.61116347 |
80 | KSR2 | 0.60230054 |
81 | ZAK | 0.60217378 |
82 | BUB1 | 0.60077954 |
83 | PDK4 | 0.58261059 |
84 | PDK3 | 0.58261059 |
85 | INSR | 0.58207107 |
86 | KSR1 | 0.58173234 |
87 | RET | 0.57980842 |
88 | FGFR2 | 0.57904188 |
89 | NEK1 | 0.57854515 |
90 | TIE1 | 0.57196654 |
91 | CLK1 | 0.56947842 |
92 | PRKD1 | 0.53483324 |
93 | PAK1 | 0.52340183 |
94 | CAMK1G | 0.51677754 |
95 | GSK3A | 0.51354064 |
96 | CDK8 | 0.50715771 |
97 | PDK2 | 0.48206274 |
98 | TAF1 | 0.43807677 |
99 | NEK2 | 0.43262158 |
100 | FGFR3 | 0.42352102 |
101 | YES1 | 0.41138312 |
102 | PBK | 0.40322351 |
103 | CDK9 | 0.40162654 |
104 | MST1R | 0.40082108 |
105 | TAOK2 | 0.39959554 |
106 | TEC | 0.38327128 |
107 | RAF1 | 0.37209305 |
108 | ICK | 0.37049555 |
109 | FGFR4 | 0.36809862 |
110 | CDK7 | 0.36338015 |
111 | AKT3 | 0.35256159 |
112 | DAPK3 | 0.34770239 |
113 | CHEK2 | 0.34730212 |
114 | ZAP70 | 0.34367231 |
115 | NTRK1 | 0.34236805 |
116 | PRKD3 | 0.32520315 |
117 | ERBB4 | 0.31562416 |
118 | * SRC | 0.31341988 |
119 | JAK1 | 0.30987898 |
120 | PRKD2 | 0.28008137 |
121 | MAPKAPK2 | 0.27592488 |
122 | EGFR | 0.27079419 |
123 | CHEK1 | 0.26898966 |
124 | ALK | 0.26879054 |
125 | AURKB | 0.26719155 |
126 | RPS6KA2 | 0.25721509 |
127 | AKT2 | 0.24418608 |
128 | WNK1 | 0.24269791 |
129 | ABL2 | 0.24015733 |
130 | OBSCN | 0.23606053 |
131 | PIM2 | 0.23553991 |
132 | MAPK1 | 0.23516299 |
133 | PRKCH | 0.23469356 |
Rank | Gene Set | Z-score |
---|---|---|
1 | ECM-receptor interaction_Homo sapiens_hsa04512 | 4.17128570 |
2 | * Focal adhesion_Homo sapiens_hsa04510 | 3.25191514 |
3 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 2.79989385 |
4 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 2.75062176 |
5 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 2.65995432 |
6 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 2.60289165 |
7 | * Adherens junction_Homo sapiens_hsa04520 | 2.47865408 |
8 | Small cell lung cancer_Homo sapiens_hsa05222 | 2.36876533 |
9 | * Amoebiasis_Homo sapiens_hsa05146 | 2.16999753 |
10 | * Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 2.16494284 |
11 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 2.08688444 |
12 | Bladder cancer_Homo sapiens_hsa05219 | 2.05125063 |
13 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 2.02887598 |
14 | Hippo signaling pathway_Homo sapiens_hsa04390 | 2.00416048 |
15 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 1.93972583 |
16 | Protein digestion and absorption_Homo sapiens_hsa04974 | 1.78876656 |
17 | Viral myocarditis_Homo sapiens_hsa05416 | 1.73565772 |
18 | Tight junction_Homo sapiens_hsa04530 | 1.70334455 |
19 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 1.68483394 |
20 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 1.66008228 |
21 | * Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 1.62563384 |
22 | * Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 1.59457114 |
23 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 1.56496482 |
24 | Malaria_Homo sapiens_hsa05144 | 1.53556551 |
25 | PI3K-Akt signaling pathway_Homo sapiens_hsa04151 | 1.44887860 |
26 | Basal cell carcinoma_Homo sapiens_hsa05217 | 1.40726951 |
27 | p53 signaling pathway_Homo sapiens_hsa04115 | 1.39561183 |
28 | Platelet activation_Homo sapiens_hsa04611 | 1.22367856 |
29 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 1.21892714 |
30 | Melanoma_Homo sapiens_hsa05218 | 1.19572741 |
31 | Toxoplasmosis_Homo sapiens_hsa05145 | 1.19003994 |
32 | Pathways in cancer_Homo sapiens_hsa05200 | 1.11295209 |
33 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 1.10932751 |
34 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 1.10707029 |
35 | Pancreatic cancer_Homo sapiens_hsa05212 | 1.08769086 |
36 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 1.08219608 |
37 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 1.06451651 |
38 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 1.06418401 |
39 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 1.06002084 |
40 | Salmonella infection_Homo sapiens_hsa05132 | 1.05431708 |
41 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 1.04189645 |
42 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 1.00769083 |
43 | * Shigellosis_Homo sapiens_hsa05131 | 0.98298149 |
44 | Prostate cancer_Homo sapiens_hsa05215 | 0.96436388 |
45 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.95914504 |
46 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.95698002 |
47 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 0.94288423 |
48 | HTLV-I infection_Homo sapiens_hsa05166 | 0.92857039 |
49 | Glioma_Homo sapiens_hsa05214 | 0.88007120 |
50 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.85210433 |
51 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.83063954 |
52 | Insulin resistance_Homo sapiens_hsa04931 | 0.82350615 |
53 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.82312679 |
54 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.82249223 |
55 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.81012516 |
56 | Galactose metabolism_Homo sapiens_hsa00052 | 0.79561149 |
57 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.79470965 |
58 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.79418642 |
59 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.78945267 |
60 | Endometrial cancer_Homo sapiens_hsa05213 | 0.74431755 |
61 | Leishmaniasis_Homo sapiens_hsa05140 | 0.74288544 |
62 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.73527530 |
63 | Apoptosis_Homo sapiens_hsa04210 | 0.72789485 |
64 | Axon guidance_Homo sapiens_hsa04360 | 0.72695255 |
65 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.70659083 |
66 | Colorectal cancer_Homo sapiens_hsa05210 | 0.69801363 |
67 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.69770218 |
68 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.69204685 |
69 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.67569525 |
70 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.67425354 |
71 | Lysine degradation_Homo sapiens_hsa00310 | 0.66465571 |
72 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.65746131 |
73 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.64920123 |
74 | Mismatch repair_Homo sapiens_hsa03430 | 0.64568517 |
75 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.63156774 |
76 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.62318359 |
77 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.60908616 |
78 | Hepatitis B_Homo sapiens_hsa05161 | 0.60640379 |
79 | Renin-angiotensin system_Homo sapiens_hsa04614 | 0.60120108 |
80 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.58861446 |
81 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.57457628 |
82 | DNA replication_Homo sapiens_hsa03030 | 0.54965401 |
83 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.54965222 |
84 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.54860814 |
85 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.54774687 |
86 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.54525912 |
87 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.54382896 |
88 | Phagosome_Homo sapiens_hsa04145 | 0.54049171 |
89 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.53834467 |
90 | PPAR signaling pathway_Homo sapiens_hsa03320 | 0.53520939 |
91 | Melanogenesis_Homo sapiens_hsa04916 | 0.50996810 |
92 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.50886178 |
93 | Cell cycle_Homo sapiens_hsa04110 | 0.50724715 |
94 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.50515417 |
95 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.50145791 |
96 | Thyroid cancer_Homo sapiens_hsa05216 | 0.49646582 |
97 | Gap junction_Homo sapiens_hsa04540 | 0.48086729 |
98 | Endocytosis_Homo sapiens_hsa04144 | 0.47907907 |
99 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.47306740 |
100 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.45923156 |
101 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.43472391 |
102 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.43200605 |
103 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.42497603 |
104 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.42141587 |
105 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.41360367 |
106 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.41232717 |
107 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.41184022 |
108 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.41142720 |
109 | Carbon metabolism_Homo sapiens_hsa01200 | 0.40987463 |
110 | RNA transport_Homo sapiens_hsa03013 | 0.40561667 |
111 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.40243078 |
112 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.39377329 |
113 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 0.39109192 |
114 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 0.38418793 |
115 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.38313118 |
116 | Pertussis_Homo sapiens_hsa05133 | 0.38019598 |
117 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.37317412 |
118 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.37293414 |
119 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.37215014 |
120 | Osteoclast differentiation_Homo sapiens_hsa04380 | 0.34941361 |
121 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.34839220 |
122 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.34220602 |
123 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.34111024 |
124 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.33885492 |