VCP

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: The protein encoded by this gene is a member of a family that includes putative ATP-binding proteins involved in vesicle transport and fusion, 26S proteasome function, and assembly of peroxisomes. This protein, as a structural protein, is associated with clathrin, and heat-shock protein Hsc70, to form a complex. It has been implicated in a number of cellular events that are regulated during mitosis, including homotypic membrane fusion, spindle pole body function, and ubiquitin-dependent protein degradation. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1COPI coating of Golgi vesicle (GO:0048205)5.87879031
2Golgi transport vesicle coating (GO:0048200)5.87879031
3DNA unwinding involved in DNA replication (GO:0006268)5.16901187
4regulation of translational termination (GO:0006449)4.34544563
5regulation of translational fidelity (GO:0006450)4.19619802
6negative regulation of cell size (GO:0045792)4.16032718
7folic acid-containing compound biosynthetic process (GO:0009396)4.08693592
8mitotic chromosome condensation (GO:0007076)3.98028081
9peptidyl-lysine dimethylation (GO:0018027)3.96986627
10hemidesmosome assembly (GO:0031581)3.79105505
11peptidyl-arginine omega-N-methylation (GO:0035247)3.78645553
12activation of signaling protein activity involved in unfolded protein response (GO:0006987)3.72786703
13establishment of integrated proviral latency (GO:0075713)3.72028922
14positive regulation of nuclease activity (GO:0032075)3.71431700
15protein localization to endosome (GO:0036010)3.69639677
16heterochromatin organization (GO:0070828)3.69409774
17proline biosynthetic process (GO:0006561)3.66754479
18polarized epithelial cell differentiation (GO:0030859)3.62340645
19protein maturation by protein folding (GO:0022417)3.55681384
20retrograde vesicle-mediated transport, Golgi to ER (GO:0006890)3.50071812
21plasma membrane repair (GO:0001778)3.48705339
22maternal placenta development (GO:0001893)3.48397779
23protein complex localization (GO:0031503)3.44234169
24pentose-phosphate shunt (GO:0006098)3.43970870
25cell-substrate junction assembly (GO:0007044)3.40349373
26regulation of nuclease activity (GO:0032069)3.37142858
27nuclear pore organization (GO:0006999)3.33824620
28cell adhesion mediated by integrin (GO:0033627)3.31510369
29pre-miRNA processing (GO:0031054)3.30018749
30glucocorticoid receptor signaling pathway (GO:0042921)3.29032487
31pore complex assembly (GO:0046931)3.28539607
32focal adhesion assembly (GO:0048041)3.27818162
33cell-substrate adherens junction assembly (GO:0007045)3.27818162
34cellular protein complex localization (GO:0034629)3.23731382
35negative regulation of mRNA splicing, via spliceosome (GO:0048025)3.23171692
36peptidyl-arginine methylation (GO:0018216)3.23030589
37peptidyl-arginine N-methylation (GO:0035246)3.23030589
38NADPH regeneration (GO:0006740)3.21282848
39nuclear pore complex assembly (GO:0051292)3.21246425
40establishment of viral latency (GO:0019043)3.20147538
41IMP biosynthetic process (GO:0006188)3.17942026
42maintenance of protein localization in endoplasmic reticulum (GO:0035437)3.15562045
43spliceosomal tri-snRNP complex assembly (GO:0000244)3.14261894
44embryonic foregut morphogenesis (GO:0048617)3.08729497
45dosage compensation (GO:0007549)3.08271851
46hippo signaling (GO:0035329)3.06880480
47basement membrane organization (GO:0071711)3.06364218
48mitotic G1 DNA damage checkpoint (GO:0031571)3.06103076
49epithelial cell differentiation involved in prostate gland development (GO:0060742)3.04508582
50* endoplasmic reticulum unfolded protein response (GO:0030968)3.03001898
51nuclear envelope reassembly (GO:0031468)3.02224711
52mitotic nuclear envelope reassembly (GO:0007084)3.02224711
53regulation of mammary gland epithelial cell proliferation (GO:0033599)2.94654851
54positive regulation of SMAD protein import into nucleus (GO:0060391)2.94338382
55chaperone-mediated protein complex assembly (GO:0051131)2.94002741
56nucleobase-containing small molecule interconversion (GO:0015949)2.93579078
57cytoskeletal anchoring at plasma membrane (GO:0007016)2.93018381
58regulation of hippo signaling (GO:0035330)2.91710479
59paraxial mesoderm development (GO:0048339)2.90467756
60histone arginine methylation (GO:0034969)2.88733147
61vesicle coating (GO:0006901)2.85879333
62formation of translation preinitiation complex (GO:0001731)2.85113007
63glucose catabolic process (GO:0006007)2.84530321
64pinocytosis (GO:0006907)2.84522438
65establishment of apical/basal cell polarity (GO:0035089)2.84507142
66* cellular response to unfolded protein (GO:0034620)2.82417683
67* ER-nucleus signaling pathway (GO:0006984)2.82051730
68regulation of translational elongation (GO:0006448)2.81974425
69COPII vesicle coating (GO:0048208)2.81573384
70DNA strand elongation involved in DNA replication (GO:0006271)2.81098655
71skin morphogenesis (GO:0043589)2.81041420
72ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway (GO:0043162.80756077
73protein export from nucleus (GO:0006611)2.78888376
74NLS-bearing protein import into nucleus (GO:0006607)2.78474682
75mitotic nuclear envelope disassembly (GO:0007077)2.78239334
76regulation of SMAD protein import into nucleus (GO:0060390)2.78006744
77DNA strand elongation (GO:0022616)2.76592671
78barbed-end actin filament capping (GO:0051016)2.76187596
79alternative mRNA splicing, via spliceosome (GO:0000380)2.76145074
80membrane disassembly (GO:0030397)2.76011969
81nuclear envelope disassembly (GO:0051081)2.76011969
82protein localization to kinetochore (GO:0034501)2.75940410
83IMP metabolic process (GO:0046040)2.74839194
84tricarboxylic acid metabolic process (GO:0072350)2.74436402
85regulation of attachment of spindle microtubules to kinetochore (GO:0051988)2.72195067
864-hydroxyproline metabolic process (GO:0019471)2.71656980
87negative regulation of RNA splicing (GO:0033119)2.70614976
88regulation of glucose import in response to insulin stimulus (GO:2001273)2.70346810
89positive regulation of extrinsic apoptotic signaling pathway in absence of ligand (GO:2001241)2.68678087
90positive regulation of cell size (GO:0045793)2.68650503
91positive regulation of RNA splicing (GO:0033120)2.68327086
92mRNA stabilization (GO:0048255)2.67506416
93RNA stabilization (GO:0043489)2.67506416
94protein retention in ER lumen (GO:0006621)2.67419268
95DNA duplex unwinding (GO:0032508)2.66693134
96DNA replication-dependent nucleosome assembly (GO:0006335)2.65952784
97DNA replication-dependent nucleosome organization (GO:0034723)2.65952784
98regulation of RNA export from nucleus (GO:0046831)2.65354858
99* cellular response to topologically incorrect protein (GO:0035967)2.63559175
100protein localization to chromosome, centromeric region (GO:0071459)2.62975142
101regulation of posttranscriptional gene silencing (GO:0060147)2.62469177
102regulation of gene silencing by miRNA (GO:0060964)2.62469177
103regulation of gene silencing by RNA (GO:0060966)2.62469177
104ribosome assembly (GO:0042255)2.61988613
105DNA geometric change (GO:0032392)2.61054719
106negative regulation of mRNA metabolic process (GO:1903312)2.60998742
107positive regulation of receptor biosynthetic process (GO:0010870)2.60990876
108mitotic G1/S transition checkpoint (GO:0044819)2.60300722
109regulation of low-density lipoprotein particle receptor biosynthetic process (GO:0045714)2.60239741
110epithelial cell-cell adhesion (GO:0090136)2.59687334
111adherens junction assembly (GO:0034333)2.59039438
112negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471)2.58538719
113stress fiber assembly (GO:0043149)2.58506366
114regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450912.57402192
115regulation of NFAT protein import into nucleus (GO:0051532)2.57259770
116gap junction assembly (GO:0016264)2.57199539
117negative regulation of mRNA processing (GO:0050686)2.57033977
118regulation of early endosome to late endosome transport (GO:2000641)2.56028883
119mitochondrial fusion (GO:0008053)2.55721918
120regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)2.55700395
121endodermal cell differentiation (GO:0035987)2.53806501
122negative regulation of microtubule polymerization (GO:0031115)2.53784630
123establishment of monopolar cell polarity (GO:0061162)2.53004537
124establishment or maintenance of monopolar cell polarity (GO:0061339)2.53004537
125desmosome organization (GO:0002934)2.52406445
126regulation of nucleobase-containing compound transport (GO:0032239)2.51403678
127activation of Rac GTPase activity (GO:0032863)2.50694516
128regulation of fatty acid beta-oxidation (GO:0031998)2.50427339
129mitotic metaphase plate congression (GO:0007080)2.50297355
130DNA replication initiation (GO:0006270)2.49993481
131dichotomous subdivision of an epithelial terminal unit (GO:0060600)2.49667116
132negative regulation of cell fate specification (GO:0009996)2.49051776
133corticosteroid receptor signaling pathway (GO:0031958)2.49048579
134embryonic process involved in female pregnancy (GO:0060136)2.48227425
135histone H2A monoubiquitination (GO:0035518)2.47840898
1363-UTR-mediated mRNA stabilization (GO:0070935)2.47582503
137ectodermal placode formation (GO:0060788)2.47165715
138mitotic sister chromatid segregation (GO:0000070)2.46234466
139nuclear envelope organization (GO:0006998)2.43485444
140apoptotic process involved in morphogenesis (GO:0060561)2.41362000
141G1 DNA damage checkpoint (GO:0044783)2.41288332
142chromatin assembly (GO:0031497)2.41207421
143gene silencing by RNA (GO:0031047)2.40587855
144L-serine metabolic process (GO:0006563)2.39864419
145planar cell polarity pathway involved in neural tube closure (GO:0090179)2.39799757
146negative regulation of DNA repair (GO:0045738)2.39749232
147cellular response to epidermal growth factor stimulus (GO:0071364)2.38945102
148negative regulation of fatty acid transport (GO:2000192)2.37556300
149membrane protein ectodomain proteolysis (GO:0006509)2.37039008
150response to epidermal growth factor (GO:0070849)2.36543319
151positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling2.36370119

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human5.38039304
2EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.46722905
3EGR1_19374776_ChIP-ChIP_THP-1_Human3.34725136
4FOXM1_23109430_ChIP-Seq_U2OS_Human3.23797011
5NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse3.05315526
6CLOCK_20551151_ChIP-Seq_293T_Human2.97040623
7MYC_18555785_ChIP-Seq_MESCs_Mouse2.65491265
8ZNF263_19887448_ChIP-Seq_K562_Human2.55085103
9MYC_22102868_ChIP-Seq_BL_Human2.47884148
10PPARG_19300518_ChIP-PET_3T3-L1_Mouse2.40657165
11HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.34316543
12TP63_17297297_ChIP-ChIP_HaCaT_Human2.21387846
13AR_21909140_ChIP-Seq_LNCAP_Human2.11356248
14* MYC_19079543_ChIP-ChIP_MESCs_Mouse2.06842239
15ESR1_15608294_ChIP-ChIP_MCF-7_Human1.86701680
16XRN2_22483619_ChIP-Seq_HELA_Human1.86052350
17RARG_19884340_ChIP-ChIP_MEFs_Mouse1.82341910
18ZFP281_18757296_ChIP-ChIP_E14_Mouse1.81841540
19TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.77174041
20* ZFX_18555785_ChIP-Seq_MESCs_Mouse1.76665263
21NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.75330617
22ELK3_25401928_ChIP-Seq_HUVEC_Human1.74425425
23NELFA_20434984_ChIP-Seq_ESCs_Mouse1.71706074
24KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.69940674
25POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.68185882
26* CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.65803503
27ATF3_27146783_Chip-Seq_COLON_Human1.65702431
28TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.65661898
29ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.65328829
30* CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.60827024
31FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.60230053
32TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.59797820
33E2F4_17652178_ChIP-ChIP_JURKAT_Human1.58092932
34* KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.57049865
35P300_27058665_Chip-Seq_ZR-75-30cells_Human1.55949454
36KDM2B_26808549_Chip-Seq_DND41_Human1.53696226
37TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.53007838
38MYC_19030024_ChIP-ChIP_MESCs_Mouse1.51502310
39KLF4_18555785_ChIP-Seq_MESCs_Mouse1.50068220
40HIF1A_21447827_ChIP-Seq_MCF-7_Human1.49808409
41VDR_21846776_ChIP-Seq_THP-1_Human1.47912826
42CIITA_25753668_ChIP-Seq_RAJI_Human1.47053237
43ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.45208715
44STAT3_1855785_ChIP-Seq_MESCs_Mouse1.44318776
45* RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.44269206
46DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.44032437
47NANOG_18555785_ChIP-Seq_MESCs_Mouse1.43400770
48RACK7_27058665_Chip-Seq_MCF-7_Human1.42856769
49* CHD1_26751641_Chip-Seq_LNCaP_Human1.42451438
50* SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.41437183
51* TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.40832998
52THAP11_20581084_ChIP-Seq_MESCs_Mouse1.39243701
53ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.38858241
54KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.38673092
55KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.38622575
56MYC_18358816_ChIP-ChIP_MESCs_Mouse1.37397235
57SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.37340434
58CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.35634395
59LXR_22292898_ChIP-Seq_THP-1_Human1.34921230
60KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.32055835
61KDM5A_27292631_Chip-Seq_BREAST_Human1.30799989
62* PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.30460739
63STAT6_21828071_ChIP-Seq_BEAS2B_Human1.29834164
64MYCN_18555785_ChIP-Seq_MESCs_Mouse1.29752763
65CREB1_15753290_ChIP-ChIP_HEK293T_Human1.29057364
66STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.28628156
67NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.27030704
68TFEB_21752829_ChIP-Seq_HELA_Human1.26796998
69KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.25474784
70MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.24383207
71E2F1_21310950_ChIP-Seq_MCF-7_Human1.23445960
72TCF7_22412390_ChIP-Seq_EML_Mouse1.21044556
73SREBP1_19666523_ChIP-Seq_LIVER_Mouse1.20543352
74ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.20405751
75NANOG_21062744_ChIP-ChIP_HESCs_Human1.20055795
76WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.19161521
77TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.18930924
78FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human1.18170931
79NKX2-5_21415370_ChIP-Seq_HL-1_Mouse1.17213844
80KDM2B_26808549_Chip-Seq_SUP-B15_Human1.15912171
81* CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.15886235
82POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.14116574
83DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.13570514
84TP53_22127205_ChIP-Seq_IMR90_Human1.13415288
85TRIM28_21343339_ChIP-Seq_HEK293_Human1.12410931
86FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.12100878
87CREB1_26743006_Chip-Seq_LNCaP_Human1.11879467
88JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.11459082
89PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.10896170
90* E2F1_18555785_ChIP-Seq_MESCs_Mouse1.10818684
91THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.08914071
92TCF3_18692474_ChIP-Seq_MEFs_Mouse1.08743419
93UBF1/2_26484160_Chip-Seq_HMECs_Human1.08129422
94GABP_19822575_ChIP-Seq_HepG2_Human1.07796832
95* TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.07638266
96SRY_22984422_ChIP-ChIP_TESTIS_Rat1.07427042
97ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.07102261
98TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.06587806
99* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.05424417
100OCT4_18692474_ChIP-Seq_MEFs_Mouse1.05397425
101ZFP281_27345836_Chip-Seq_ESCs_Mouse1.04906888
102HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse1.04399040
103TTF2_22483619_ChIP-Seq_HELA_Human1.04301997
104NCOR1_26117541_ChIP-Seq_K562_Human1.04264108
105CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.04174329
106DCP1A_22483619_ChIP-Seq_HELA_Human1.03773620
107ETS1_20019798_ChIP-Seq_JURKAT_Human1.03517566
108TET1_21451524_ChIP-Seq_MESCs_Mouse1.02821853
109NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.02586473
110PPARA_22158963_ChIP-Seq_LIVER_Mouse1.01403258
111* EOMES_20176728_ChIP-ChIP_TSCs_Mouse1.01351644
112SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.00730503
113SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.00667757
114* UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human0.99028919
115GATA6_25053715_ChIP-Seq_YYC3_Human0.98537784
116SMAD2_18955504_ChIP-ChIP_HaCaT_Human0.98281196
117SMAD3_18955504_ChIP-ChIP_HaCaT_Human0.98281196
118GATA3_20176728_ChIP-ChIP_TSCs_Mouse0.98045995
119KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.96375514
120TCFCP2L1_18555785_ChIP-Seq_MESCs_Mouse0.96128611
121ESR2_21235772_ChIP-Seq_MCF-7_Human0.95908406
122* P68_20966046_ChIP-Seq_HELA_Human0.95210080
123EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse0.94429764

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003705_abnormal_hypodermis_morpholog4.15812415
2MP0010352_gastrointestinal_tract_polyps3.29772756
3MP0000537_abnormal_urethra_morphology2.81278683
4MP0008438_abnormal_cutaneous_collagen2.78217183
5MP0003283_abnormal_digestive_organ2.69774740
6MP0010234_abnormal_vibrissa_follicle2.61430109
7MP0005451_abnormal_body_composition2.51759224
8MP0005076_abnormal_cell_differentiation2.42015098
9MP0003941_abnormal_skin_development2.23792586
10MP0001730_embryonic_growth_arrest2.19610128
11MP0003566_abnormal_cell_adhesion2.15620643
12MP0003123_paternal_imprinting2.09310459
13MP0004957_abnormal_blastocyst_morpholog1.94123883
14MP0004272_abnormal_basement_membrane1.87220371
15MP0010030_abnormal_orbit_morphology1.87114274
16MP0005623_abnormal_meninges_morphology1.86174559
17MP0004197_abnormal_fetal_growth/weight/1.83826581
18MP0000733_abnormal_muscle_development1.83435567
19MP0004233_abnormal_muscle_weight1.82637019
20MP0002796_impaired_skin_barrier1.75266504
21MP0003300_gastrointestinal_ulcer1.74905840
22MP0009053_abnormal_anal_canal1.72679439
23MP0004084_abnormal_cardiac_muscle1.70665528
24MP0001849_ear_inflammation1.68934747
25MP0005275_abnormal_skin_tensile1.66415271
26MP0009840_abnormal_foam_cell1.66004326
27MP0005501_abnormal_skin_physiology1.65701806
28MP0002877_abnormal_melanocyte_morpholog1.63642096
29MP0006054_spinal_hemorrhage1.62048977
30MP0002084_abnormal_developmental_patter1.61800702
31MP0005058_abnormal_lysosome_morphology1.60128679
32MP0002060_abnormal_skin_morphology1.54159749
33MP0001697_abnormal_embryo_size1.53772864
34MP0003453_abnormal_keratinocyte_physiol1.52600200
35MP0005187_abnormal_penis_morphology1.49640107
36MP0004185_abnormal_adipocyte_glucose1.49375928
37MP0000350_abnormal_cell_proliferation1.46821546
38MP0002085_abnormal_embryonic_tissue1.40901567
39MP0002269_muscular_atrophy1.39790587
40MP0002088_abnormal_embryonic_growth/wei1.39549586
41MP0003111_abnormal_nucleus_morphology1.39543642
42* MP0002080_prenatal_lethality1.39145507
43MP0000428_abnormal_craniofacial_morphol1.39107432
44MP0003984_embryonic_growth_retardation1.39036728
45MP0001672_abnormal_embryogenesis/_devel1.39027100
46MP0005380_embryogenesis_phenotype1.39027100
47MP0000579_abnormal_nail_morphology1.36431130
48MP0003567_abnormal_fetal_cardiomyocyte1.34548800
49* MP0000747_muscle_weakness1.34100743
50MP0000013_abnormal_adipose_tissue1.32631868
51MP0010307_abnormal_tumor_latency1.31315304
52MP0000003_abnormal_adipose_tissue1.31128584
53MP0002234_abnormal_pharynx_morphology1.30958579
54MP0003693_abnormal_embryo_hatching1.30948418
55MP0010368_abnormal_lymphatic_system1.30788035
56MP0003119_abnormal_digestive_system1.27603497
57MP0001348_abnormal_lacrimal_gland1.27461120
58MP0009672_abnormal_birth_weight1.26806871
59MP0002086_abnormal_extraembryonic_tissu1.25734347
60MP0000534_abnormal_ureter_morphology1.25352766
61MP0005023_abnormal_wound_healing1.25269249
62MP0008932_abnormal_embryonic_tissue1.24935710
63* MP0004087_abnormal_muscle_fiber1.23690893
64MP0000750_abnormal_muscle_regeneration1.23240513
65MP0000762_abnormal_tongue_morphology1.23221128
66MP0003077_abnormal_cell_cycle1.21203285
67MP0001661_extended_life_span1.18974399
68MP0005666_abnormal_adipose_tissue1.18954227
69MP0003221_abnormal_cardiomyocyte_apopto1.18290917
70MP0004264_abnormal_extraembryonic_tissu1.15659060
71MP0003122_maternal_imprinting1.15195844
72MP0003115_abnormal_respiratory_system1.14402022
73MP0005375_adipose_tissue_phenotype1.13475978
74MP0009278_abnormal_bone_marrow1.12656809
75MP0003942_abnormal_urinary_system1.12567155
76MP0003191_abnormal_cellular_cholesterol1.11745310
77MP0001216_abnormal_epidermal_layer1.08783734
78MP0008961_abnormal_basal_metabolism1.07965297
79MP0000858_altered_metastatic_potential1.06726956
80MP0010094_abnormal_chromosome_stability1.06643845
81* MP0005621_abnormal_cell_physiology1.06373748
82MP0000467_abnormal_esophagus_morphology1.06022743
83MP0010630_abnormal_cardiac_muscle1.04979577
84MP0003315_abnormal_perineum_morphology1.04557667
85MP0003091_abnormal_cell_migration1.03340109
86MP0002697_abnormal_eye_size1.03305334
87MP0000490_abnormal_crypts_of1.02632784
88MP0005083_abnormal_biliary_tract1.02308478
89MP0002896_abnormal_bone_mineralization1.01639788
90MP0001915_intracranial_hemorrhage1.01171781
91MP0004130_abnormal_muscle_cell1.00086274
92MP0003385_abnormal_body_wall0.99803814
93MP0009703_decreased_birth_body0.98981541
94MP0002837_dystrophic_cardiac_calcinosis0.97686612
95MP0001299_abnormal_eye_distance/0.97442063
96MP0005330_cardiomyopathy0.97355393
97MP0002653_abnormal_ependyma_morphology0.97240588
98MP0003806_abnormal_nucleotide_metabolis0.94022346
99MP0005220_abnormal_exocrine_pancreas0.92767583
100MP0000358_abnormal_cell_content/0.92621771
101MP0003279_aneurysm0.92335686
102MP0003121_genomic_imprinting0.91345862
103MP0001243_abnormal_dermal_layer0.90437948
104MP0009780_abnormal_chondrocyte_physiolo0.90288513
105MP0005409_darkened_coat_color0.90028012
106* MP0000759_abnormal_skeletal_muscle0.89868832
107MP0004036_abnormal_muscle_relaxation0.88269396
108MP0001958_emphysema0.88073267
109MP0004858_abnormal_nervous_system0.87675318
110MP0004782_abnormal_surfactant_physiolog0.87419343
111* MP0005384_cellular_phenotype0.87022862
112MP0000462_abnormal_digestive_system0.86925342
113MP0002909_abnormal_adrenal_gland0.86333722
114MP0008007_abnormal_cellular_replicative0.85855706
115MP0000767_abnormal_smooth_muscle0.85745519
116MP0003890_abnormal_embryonic-extraembry0.84151351
117MP0000266_abnormal_heart_morphology0.83472169
118MP0002282_abnormal_trachea_morphology0.81664490
119MP0002925_abnormal_cardiovascular_devel0.81607627
120MP0002111_abnormal_tail_morphology0.81296011
121* MP0000751_myopathy0.80871586
122MP0000313_abnormal_cell_death0.80745264
123MP0003329_amyloid_beta_deposits0.78411969
124MP0003950_abnormal_plasma_membrane0.78057261
125MP0002089_abnormal_postnatal_growth/wei0.78019007
126MP0001727_abnormal_embryo_implantation0.77566831
127MP0003935_abnormal_craniofacial_develop0.76602020
128MP0000627_abnormal_mammary_gland0.76408702
129MP0002932_abnormal_joint_morphology0.75789576
130MP0005503_abnormal_tendon_morphology0.75138669
131MP0000377_abnormal_hair_follicle0.74204123
132MP0002092_abnormal_eye_morphology0.74145760
133MP0000749_muscle_degeneration0.73612021
134MP0005257_abnormal_intraocular_pressure0.73071555

Predicted human phenotypes

RankGene SetZ-score
1Protrusio acetabuli (HP:0003179)3.74773027
2Cerebral aneurysm (HP:0004944)3.24624490
3Premature rupture of membranes (HP:0001788)3.21557892
4Vertebral compression fractures (HP:0002953)3.14125078
5Ankle contracture (HP:0006466)3.12609995
6Distal lower limb amyotrophy (HP:0008944)3.08962621
7Hyperacusis (HP:0010780)3.02521239
8Short nail (HP:0001799)3.01600541
9Hand muscle atrophy (HP:0009130)2.98057170
10Distal upper limb amyotrophy (HP:0007149)2.97581955
11Upper limb amyotrophy (HP:0009129)2.97581955
12Ependymoma (HP:0002888)2.88746705
13Shallow orbits (HP:0000586)2.79685549
14Abnormality of the calcaneus (HP:0008364)2.79589211
15Increased connective tissue (HP:0009025)2.79240686
16Atrophic scars (HP:0001075)2.73435349
17Bowel diverticulosis (HP:0005222)2.66181694
18Lymphangioma (HP:0100764)2.63545144
19Centrally nucleated skeletal muscle fibers (HP:0003687)2.63041643
20Bladder diverticulum (HP:0000015)2.62395373
21Angiofibromas (HP:0010615)2.57460821
22Adenoma sebaceum (HP:0009720)2.57460821
23Type 1 muscle fiber predominance (HP:0003803)2.50117417
24Difficulty running (HP:0009046)2.46279355
25Distal lower limb muscle weakness (HP:0009053)2.45957286
26Osteolytic defects of the hand bones (HP:0009699)2.44176193
27Osteolytic defects of the phalanges of the hand (HP:0009771)2.44176193
28Flat acetabular roof (HP:0003180)2.43938334
29Renal duplication (HP:0000075)2.42163588
30Lower limb amyotrophy (HP:0007210)2.39810387
31Selective tooth agenesis (HP:0001592)2.38765309
32Hyporeflexia of lower limbs (HP:0002600)2.38349778
33Enlarged penis (HP:0000040)2.33286303
34Fragile skin (HP:0001030)2.31496584
35Spastic diplegia (HP:0001264)2.30198128
36Ulnar deviation of the wrist (HP:0003049)2.28141969
37Increased density of long bones (HP:0006392)2.26983644
38Cervical subluxation (HP:0003308)2.25428509
39Natal tooth (HP:0000695)2.22881801
40Myoglobinuria (HP:0002913)2.21082014
41Abnormality of the astrocytes (HP:0100707)2.19662868
42Astrocytoma (HP:0009592)2.19662868
43Abnormality of the distal phalanges of the toes (HP:0010182)2.19611970
44Rectal prolapse (HP:0002035)2.17990983
45Progressive muscle weakness (HP:0003323)2.17722368
46Insomnia (HP:0100785)2.17454597
47Long palpebral fissure (HP:0000637)2.16351295
48Calcaneovalgus deformity (HP:0001848)2.15415647
49Aneurysm (HP:0002617)2.15231238
50Thin bony cortex (HP:0002753)2.14016109
51Fibroma (HP:0010614)2.13317128
52Achilles tendon contracture (HP:0001771)2.11007401
53Deviation of the thumb (HP:0009603)2.10428643
54Dilatation of the ascending aorta (HP:0005111)2.09754031
55Proximal placement of thumb (HP:0009623)2.09650604
56Pseudobulbar signs (HP:0002200)2.09123726
57Elfin facies (HP:0004428)2.08119943
58Broad face (HP:0000283)2.07428269
59Termporal pattern (HP:0011008)2.06617555
60Insidious onset (HP:0003587)2.06617555
61Wormian bones (HP:0002645)2.06082535
62Mitral valve prolapse (HP:0001634)2.05804135
63Long toe (HP:0010511)2.04678891
64Multiple enchondromatosis (HP:0005701)2.04179212
65Renovascular hypertension (HP:0100817)2.04125480
66Aortic aneurysm (HP:0004942)2.02560556
67Exercise-induced muscle cramps (HP:0003710)2.02422966
68Fibrous tissue neoplasm (HP:0012316)2.01634222
69Missing ribs (HP:0000921)2.01110253
70Hallux valgus (HP:0001822)2.00833097
71Increased variability in muscle fiber diameter (HP:0003557)2.00673298
72Advanced eruption of teeth (HP:0006288)1.99681704
73Deviation of the hallux (HP:0010051)1.99306046
74Abnormality of the Achilles tendon (HP:0005109)1.99022241
75Subacute progressive viral hepatitis (HP:0006572)1.97222968
76Deformed tarsal bones (HP:0008119)1.97208740
77Abnormality of dentin (HP:0010299)1.95554414
78Wrist flexion contracture (HP:0001239)1.94565706
79Cortical dysplasia (HP:0002539)1.93595787
80Intestinal polyposis (HP:0200008)1.93327453
81Overriding aorta (HP:0002623)1.93218932
82Hypercortisolism (HP:0001578)1.92257708
83Intestinal polyp (HP:0005266)1.91737914
84Elbow flexion contracture (HP:0002987)1.91522753
85Abnormality of the lower motor neuron (HP:0002366)1.91497177
86Metaphyseal cupping (HP:0003021)1.91376961
87Ragged-red muscle fibers (HP:0003200)1.89968598
88Abnormality of skeletal muscle fiber size (HP:0012084)1.89419907
89Asymmetry of the thorax (HP:0001555)1.89402539
90Disproportionate tall stature (HP:0001519)1.89231142
91Myopathic facies (HP:0002058)1.88826227
92* Difficulty climbing stairs (HP:0003551)1.88597263
93Short 4th metacarpal (HP:0010044)1.87843461
94Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)1.87843461
95Genu recurvatum (HP:0002816)1.87659462
96Arterial tortuosity (HP:0005116)1.87651668
97Round ear (HP:0100830)1.87528852
98Distal arthrogryposis (HP:0005684)1.87125830
99Vertebral arch anomaly (HP:0008438)1.87037168
100Increased nuchal translucency (HP:0010880)1.86850107
101Adducted thumb (HP:0001181)1.86715331
102Biliary tract neoplasm (HP:0100574)1.84520708
103Blue sclerae (HP:0000592)1.83975303
104Abnormality of the 4th metacarpal (HP:0010012)1.83866932
105Ankyloglossia (HP:0010296)1.83481982
106Spinal rigidity (HP:0003306)1.83477815
107Neoplasm of the heart (HP:0100544)1.82460802
108Abnormality of oral frenula (HP:0000190)1.81189282
109Rhabdomyolysis (HP:0003201)1.80964049
110Abnormality of the umbilical cord (HP:0010881)1.80559121
111* Scapular winging (HP:0003691)1.79731826
112Abnormality of the distal phalanx of the thumb (HP:0009617)1.79693144
113Arnold-Chiari malformation (HP:0002308)1.79448345
114Radial bowing (HP:0002986)1.79219039
115Macroorchidism (HP:0000053)1.78744403
116Mildly elevated creatine phosphokinase (HP:0008180)1.78719395
117Ulnar bowing (HP:0003031)1.78008141
118Colon cancer (HP:0003003)1.77948111
119Breech presentation (HP:0001623)1.77471712
120Frequent falls (HP:0002359)1.76261537
121Buphthalmos (HP:0000557)1.76129916
122Pointed chin (HP:0000307)1.75907186
123Vascular tortuosity (HP:0004948)1.74621944
124Abnormality of the acetabulum (HP:0003170)1.74387076
125Hammertoe (HP:0001765)1.73825803
126Exostoses (HP:0100777)1.73747835
127Broad metatarsal (HP:0001783)1.71802066
128Muscle fiber cytoplasmatic inclusion bodies (HP:0100303)1.71104277
129Spinal cord lesions (HP:0100561)1.70780730
130Syringomyelia (HP:0003396)1.70780730
131Right ventricular cardiomyopathy (HP:0011663)1.70745617
132Trismus (HP:0000211)1.70218192
133Resting tremor (HP:0002322)1.69124218
134Tetraparesis (HP:0002273)1.69093510
135Abnormal ossification of hand bones (HP:0005921)1.67940983
136Entropion (HP:0000621)1.67730215
137Muscle fiber splitting (HP:0003555)1.67463593
138Broad distal phalanx of finger (HP:0009836)1.67229088
139Patellar dislocation (HP:0002999)1.66918550
140Aortic dissection (HP:0002647)1.66704161
141Soft skin (HP:0000977)1.66313493
142Muscle fiber inclusion bodies (HP:0100299)1.65893569
143Generalized amyotrophy (HP:0003700)1.65784404
144Impaired pain sensation (HP:0007328)1.65249421
145Abnormality of pain sensation (HP:0010832)1.65249421
146Microvesicular hepatic steatosis (HP:0001414)1.63868962
147Mitral regurgitation (HP:0001653)1.63756035
148Biconcave vertebral bodies (HP:0004586)1.63688066
149Abnormality of carpal bone ossification (HP:0006257)1.62850562
150Upper motor neuron abnormality (HP:0002127)1.62603814
151Abnormal delivery (HP:0001787)1.61854800
152Pterygium (HP:0001059)1.59958172
153Cholecystitis (HP:0001082)1.59902757
154Abnormal gallbladder physiology (HP:0012438)1.59902757
155Orthostatic hypotension (HP:0001278)1.55165983
156Abnormality of the tricuspid valve (HP:0001702)1.54027615
157Exercise-induced myalgia (HP:0003738)1.51956279
158Progressive external ophthalmoplegia (HP:0000590)1.51668704

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TRIB34.79794883
2PKN23.78944296
3SMG13.40690624
4EEF2K3.35908676
5TTN2.81116534
6NEK12.45351626
7SCYL22.30192065
8IRAK32.28981569
9MAP3K102.25117156
10PASK2.18262133
11PTK62.10775819
12CDC72.04369874
13PDGFRA2.03308417
14TESK22.00338546
15NME21.98169289
16PRPF4B1.82432852
17TESK11.77492646
18TSSK61.74877057
19CDK121.72974430
20LIMK11.69789203
21PAK41.68054616
22KSR21.64988284
23LRRK21.63200812
24PBK1.57610488
25RPS6KB21.54957939
26SRPK11.50858001
27TGFBR11.43726437
28RIPK11.42448584
29SIK11.42371779
30ARAF1.40288879
31NEK21.34542558
32ERBB41.33639571
33LATS21.30910092
34ERN11.30598975
35KDR1.30085043
36ALK1.28474978
37MTOR1.25000158
38TAOK21.24481089
39MAP3K21.22590770
40MAP3K81.21872927
41PAK21.20590012
42ICK1.20427503
43WEE11.18907063
44LMTK21.18661368
45PTK21.18167347
46FER1.17578768
47RET1.15895224
48BUB11.08522470
49DDR21.07790684
50MET1.07070585
51TYRO31.01569915
52FLT30.98916920
53LATS10.98056793
54PIM20.97447569
55FGFR10.96688662
56FGFR40.96503438
57EPHA20.95758601
58CDK60.94897089
59PDK30.92061969
60PDK40.92061969
61MAP2K20.91227209
62BCKDK0.90497179
63BMX0.88470694
64ILK0.88268726
65MOS0.87244648
66MAPKAPK30.86483099
67EPHB10.85015231
68PAK30.83119586
69CDK40.81204057
70MAP2K10.80837008
71NTRK10.79264505
72STK100.78772955
73DYRK1B0.72705632
74EIF2AK10.67448098
75BRAF0.64615191
76TTK0.64372697
77ERBB20.63799357
78PRKD30.62539506
79KSR10.62191422
80CDK70.61566627
81VRK20.61202254
82CAMK1D0.59449188
83CDK90.58333173
84PDGFRB0.58318620
85PNCK0.58144301
86EPHB20.57489878
87CDK80.57356514
88MST1R0.57311178
89CHEK20.56345697
90CDK11A0.55615733
91MAP3K110.53980913
92CDK150.53824478
93CLK10.52983568
94CHEK10.52515755
95CSNK1E0.52414351
96AURKA0.52186530
97CDK180.51734050
98TAF10.50786534
99RPS6KA40.48720965
100NEK90.48220941
101MAP2K30.47848105
102PAK10.47262237
103AURKB0.46671807
104MAP3K60.46553026
105CDC42BPA0.45786110
106PAK60.45759562
107MAP3K90.45273764
108PHKG10.43342185
109PHKG20.43342185
110MAPK110.42763293
111DAPK30.42553931
112BRD40.42182871
113RPS6KA20.42132841
114CAMK1G0.41674827
115TIE10.41324642
116CDK140.40376446
117ROCK20.40284510
118CDK20.39657847
119PLK10.39102060
120STK30.37563085
121MAP3K130.37071474
122ABL20.36631423
123PRKG20.35580920
124EPHA30.35203670
125AKT20.34698064
126PRKD20.34424434
127MAP3K30.33465706
128BRSK20.32804277
129RPS6KA10.31992053
130CSNK1G30.30121756
131BRSK10.28135609
132UHMK10.25697334
133SRC0.25413733

Predicted pathways (KEGG)

RankGene SetZ-score
1Citrate cycle (TCA cycle)_Homo sapiens_hsa000203.08839905
22-Oxocarboxylic acid metabolism_Homo sapiens_hsa012102.65289059
3Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.17104922
4* Protein processing in endoplasmic reticulum_Homo sapiens_hsa041412.08986565
5Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004002.03812310
6Biosynthesis of amino acids_Homo sapiens_hsa012301.98214153
7Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.94376342
8Carbon metabolism_Homo sapiens_hsa012001.91067784
9RNA transport_Homo sapiens_hsa030131.89653488
10Central carbon metabolism in cancer_Homo sapiens_hsa052301.89284120
11One carbon pool by folate_Homo sapiens_hsa006701.70623683
12Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.68243306
13Selenocompound metabolism_Homo sapiens_hsa004501.62078121
14Spliceosome_Homo sapiens_hsa030401.59457314
15Glycolysis / Gluconeogenesis_Homo sapiens_hsa000101.58818912
16Chronic myeloid leukemia_Homo sapiens_hsa052201.57414282
17Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.55105672
18Bladder cancer_Homo sapiens_hsa052191.52608665
19Cell cycle_Homo sapiens_hsa041101.50873093
20DNA replication_Homo sapiens_hsa030301.45616423
21Base excision repair_Homo sapiens_hsa034101.44649676
22mTOR signaling pathway_Homo sapiens_hsa041501.44335479
23Fructose and mannose metabolism_Homo sapiens_hsa000511.42856787
24Thyroid cancer_Homo sapiens_hsa052161.41984708
25Hippo signaling pathway_Homo sapiens_hsa043901.39402027
26Proteoglycans in cancer_Homo sapiens_hsa052051.37975100
27Focal adhesion_Homo sapiens_hsa045101.37025286
28Pyruvate metabolism_Homo sapiens_hsa006201.36625548
29Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.35146566
30Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.33964785
31Adherens junction_Homo sapiens_hsa045201.32959778
32Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.29222162
33Tight junction_Homo sapiens_hsa045301.25702329
34Viral myocarditis_Homo sapiens_hsa054161.24519591
35Small cell lung cancer_Homo sapiens_hsa052221.22282098
36Other glycan degradation_Homo sapiens_hsa005111.21837624
37AMPK signaling pathway_Homo sapiens_hsa041521.15590443
38Nitrogen metabolism_Homo sapiens_hsa009101.15256931
39Fatty acid degradation_Homo sapiens_hsa000711.14960395
40mRNA surveillance pathway_Homo sapiens_hsa030151.14863894
41Vibrio cholerae infection_Homo sapiens_hsa051101.13243741
42MicroRNAs in cancer_Homo sapiens_hsa052061.13103075
43Insulin signaling pathway_Homo sapiens_hsa049101.12567096
44ECM-receptor interaction_Homo sapiens_hsa045121.10823494
45Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.08989283
46Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.06512220
47Endometrial cancer_Homo sapiens_hsa052131.06467638
48Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.05941922
49Oocyte meiosis_Homo sapiens_hsa041141.05525014
50Pentose phosphate pathway_Homo sapiens_hsa000301.04337300
51Lysine degradation_Homo sapiens_hsa003101.03920138
52Insulin resistance_Homo sapiens_hsa049311.03767270
53Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.02285365
54Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.02182512
55Sulfur relay system_Homo sapiens_hsa041221.01932627
56Basal cell carcinoma_Homo sapiens_hsa052170.99489479
57Viral carcinogenesis_Homo sapiens_hsa052030.99396079
58Fatty acid metabolism_Homo sapiens_hsa012120.98966831
59Colorectal cancer_Homo sapiens_hsa052100.98078243
60Hedgehog signaling pathway_Homo sapiens_hsa043400.97287197
61Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.96460188
62Steroid biosynthesis_Homo sapiens_hsa001000.94204883
63Non-homologous end-joining_Homo sapiens_hsa034500.92820682
64Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.92358614
65Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.91547892
66Mismatch repair_Homo sapiens_hsa034300.91440586
67Non-small cell lung cancer_Homo sapiens_hsa052230.91329844
68N-Glycan biosynthesis_Homo sapiens_hsa005100.91005530
69Proteasome_Homo sapiens_hsa030500.90993770
70Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.90534906
71Glioma_Homo sapiens_hsa052140.89139215
72Nucleotide excision repair_Homo sapiens_hsa034200.86888245
73VEGF signaling pathway_Homo sapiens_hsa043700.85528275
74Cysteine and methionine metabolism_Homo sapiens_hsa002700.85444085
75Renal cell carcinoma_Homo sapiens_hsa052110.84501023
76Neurotrophin signaling pathway_Homo sapiens_hsa047220.84252210
77Apoptosis_Homo sapiens_hsa042100.83441727
78Acute myeloid leukemia_Homo sapiens_hsa052210.82817627
79Glycosaminoglycan degradation_Homo sapiens_hsa005310.82398296
80Pancreatic cancer_Homo sapiens_hsa052120.80007238
81Propanoate metabolism_Homo sapiens_hsa006400.77785320
82Estrogen signaling pathway_Homo sapiens_hsa049150.76829594
83Glucagon signaling pathway_Homo sapiens_hsa049220.76779856
84Regulation of actin cytoskeleton_Homo sapiens_hsa048100.76771562
85Thyroid hormone signaling pathway_Homo sapiens_hsa049190.76654754
86HIF-1 signaling pathway_Homo sapiens_hsa040660.76042167
87Vitamin B6 metabolism_Homo sapiens_hsa007500.75611213
88p53 signaling pathway_Homo sapiens_hsa041150.74546837
89Salmonella infection_Homo sapiens_hsa051320.73627775
90AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.73562055
91Amoebiasis_Homo sapiens_hsa051460.73559984
92Antigen processing and presentation_Homo sapiens_hsa046120.72675816
93HTLV-I infection_Homo sapiens_hsa051660.72210485
94Cyanoamino acid metabolism_Homo sapiens_hsa004600.72146067
95Phenylalanine metabolism_Homo sapiens_hsa003600.72105474
96Pyrimidine metabolism_Homo sapiens_hsa002400.72093218
97Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.70269744
98Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.70036554
99Adipocytokine signaling pathway_Homo sapiens_hsa049200.69732649
100Prion diseases_Homo sapiens_hsa050200.68119804
101TGF-beta signaling pathway_Homo sapiens_hsa043500.68085956
102Maturity onset diabetes of the young_Homo sapiens_hsa049500.66133060
103Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.65967575
104Fat digestion and absorption_Homo sapiens_hsa049750.65842869
105ErbB signaling pathway_Homo sapiens_hsa040120.64306764
106Notch signaling pathway_Homo sapiens_hsa043300.64077242
107Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.63890331
108Dilated cardiomyopathy_Homo sapiens_hsa054140.62174483
109Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.60952372
110Shigellosis_Homo sapiens_hsa051310.60812754
111Arginine and proline metabolism_Homo sapiens_hsa003300.58456340
112Butanoate metabolism_Homo sapiens_hsa006500.57791383
113Galactose metabolism_Homo sapiens_hsa000520.57693612
114Prolactin signaling pathway_Homo sapiens_hsa049170.57501504
115Protein digestion and absorption_Homo sapiens_hsa049740.57122553
116Epstein-Barr virus infection_Homo sapiens_hsa051690.57099997
117Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.56777645
118Leukocyte transendothelial migration_Homo sapiens_hsa046700.56672582
119Tryptophan metabolism_Homo sapiens_hsa003800.54889202
120Hepatitis B_Homo sapiens_hsa051610.54741466
121Prostate cancer_Homo sapiens_hsa052150.54720738
122Type II diabetes mellitus_Homo sapiens_hsa049300.53383448
123Dorso-ventral axis formation_Homo sapiens_hsa043200.52815891
124Arginine biosynthesis_Homo sapiens_hsa002200.52085304
125Gap junction_Homo sapiens_hsa045400.51659886
126Hepatitis C_Homo sapiens_hsa051600.51242770
127Pathways in cancer_Homo sapiens_hsa052000.50863074
128Lysosome_Homo sapiens_hsa041420.47704028
129Endocytosis_Homo sapiens_hsa041440.47576652

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