Rank | Gene Set | Z-score |
---|---|---|
1 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 5.01924896 |
2 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 4.70176165 |
3 | regulation of interferon-beta biosynthetic process (GO:0045357) | 4.29930582 |
4 | detection of molecule of bacterial origin (GO:0032490) | 4.20403203 |
5 | phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092) | 4.00502691 |
6 | positive regulation of interferon-alpha production (GO:0032727) | 3.99845068 |
7 | negative regulation of cell killing (GO:0031342) | 3.93848391 |
8 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 3.93848391 |
9 | tolerance induction (GO:0002507) | 3.91330744 |
10 | cellular extravasation (GO:0045123) | 3.85806924 |
11 | regulation of interferon-alpha production (GO:0032647) | 3.79326042 |
12 | modulation by organism of defense response of other organism involved in symbiotic interaction (GO:0 | 3.64629791 |
13 | positive regulation by organism of defense response of other organism involved in symbiotic interact | 3.64629791 |
14 | modulation by symbiont of host immune response (GO:0052553) | 3.64629791 |
15 | positive regulation by symbiont of host defense response (GO:0052509) | 3.64629791 |
16 | modulation by symbiont of host defense response (GO:0052031) | 3.64629791 |
17 | modulation by organism of immune response of other organism involved in symbiotic interaction (GO:00 | 3.64629791 |
18 | cytoplasmic mRNA processing body assembly (GO:0033962) | 3.56796619 |
19 | hepatocyte apoptotic process (GO:0097284) | 3.56249400 |
20 | regulation of interleukin-12 biosynthetic process (GO:0045075) | 3.55724716 |
21 | positive regulation of interleukin-8 biosynthetic process (GO:0045416) | 3.55542786 |
22 | antigen processing and presentation of endogenous antigen (GO:0019883) | 3.55217301 |
23 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 3.50079226 |
24 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 3.50079226 |
25 | monoubiquitinated protein deubiquitination (GO:0035520) | 3.47837034 |
26 | positive regulation of gamma-delta T cell activation (GO:0046645) | 3.41218645 |
27 | negative regulation of interleukin-12 production (GO:0032695) | 3.36746485 |
28 | negative regulation of T cell mediated immunity (GO:0002710) | 3.36144482 |
29 | positive regulation of tumor necrosis factor biosynthetic process (GO:0042535) | 3.35591072 |
30 | cellular response to interleukin-15 (GO:0071350) | 3.28405180 |
31 | regulation of antigen receptor-mediated signaling pathway (GO:0050854) | 3.26698937 |
32 | cellular response to interferon-alpha (GO:0035457) | 3.26215736 |
33 | positive regulation of natural killer cell differentiation (GO:0032825) | 3.25203492 |
34 | negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371) | 3.21069364 |
35 | negative regulation of T-helper cell differentiation (GO:0045623) | 3.21069364 |
36 | antigen processing and presentation via MHC class Ib (GO:0002475) | 3.20639746 |
37 | negative regulation of lymphocyte mediated immunity (GO:0002707) | 3.18796685 |
38 | detection of external biotic stimulus (GO:0098581) | 3.11434125 |
39 | neutrophil mediated immunity (GO:0002446) | 3.10179497 |
40 | positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770) | 3.06523847 |
41 | positive regulation of B cell differentiation (GO:0045579) | 3.05594897 |
42 | production of molecular mediator involved in inflammatory response (GO:0002532) | 3.04286781 |
43 | positive regulation of granulocyte differentiation (GO:0030854) | 3.04200567 |
44 | regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923) | 3.03756472 |
45 | macrophage activation involved in immune response (GO:0002281) | 3.03231924 |
46 | negative regulation of interleukin-17 production (GO:0032700) | 3.02900668 |
47 | regulation of germinal center formation (GO:0002634) | 3.01652608 |
48 | negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515) | 3.00881527 |
49 | dendritic cell migration (GO:0036336) | 2.99711136 |
50 | detection of other organism (GO:0098543) | 2.98630023 |
51 | I-kappaB phosphorylation (GO:0007252) | 2.98560278 |
52 | regulation of ARF protein signal transduction (GO:0032012) | 2.97689727 |
53 | regulation of nitric-oxide synthase biosynthetic process (GO:0051769) | 2.91854669 |
54 | positive regulation of macrophage cytokine production (GO:0060907) | 2.91643356 |
55 | myeloid leukocyte mediated immunity (GO:0002444) | 2.90977721 |
56 | positive regulation of interferon-beta production (GO:0032728) | 2.86541251 |
57 | interferon-gamma production (GO:0032609) | 2.84087322 |
58 | T-helper cell differentiation (GO:0042093) | 2.81840887 |
59 | CD4-positive, alpha-beta T cell differentiation involved in immune response (GO:0002294) | 2.81840887 |
60 | positive T cell selection (GO:0043368) | 2.81318894 |
61 | neutrophil activation involved in immune response (GO:0002283) | 2.80324578 |
62 | response to host immune response (GO:0052572) | 2.80159657 |
63 | response to immune response of other organism involved in symbiotic interaction (GO:0052564) | 2.80159657 |
64 | defense response to protozoan (GO:0042832) | 2.78636010 |
65 | regulation of protein polyubiquitination (GO:1902914) | 2.77378270 |
66 | germinal center formation (GO:0002467) | 2.74541610 |
67 | negative regulation of adaptive immune response based on somatic recombination of immune receptors b | 2.73600831 |
68 | response to type I interferon (GO:0034340) | 2.71861738 |
69 | response to interferon-alpha (GO:0035455) | 2.71694617 |
70 | natural killer cell differentiation (GO:0001779) | 2.70884183 |
71 | leukocyte aggregation (GO:0070486) | 2.70652417 |
72 | JAK-STAT cascade involved in growth hormone signaling pathway (GO:0060397) | 2.68514191 |
73 | mitotic sister chromatid cohesion (GO:0007064) | 2.67619789 |
74 | cellular response to type I interferon (GO:0071357) | 2.64311374 |
75 | type I interferon signaling pathway (GO:0060337) | 2.64311374 |
76 | positive regulation of alpha-beta T cell proliferation (GO:0046641) | 2.63936422 |
77 | response to defenses of other organism involved in symbiotic interaction (GO:0052173) | 2.63098937 |
78 | response to host (GO:0075136) | 2.63098937 |
79 | response to host defenses (GO:0052200) | 2.63098937 |
80 | negative regulation of B cell proliferation (GO:0030889) | 2.62709604 |
81 | negative regulation of adaptive immune response (GO:0002820) | 2.62653968 |
82 | protein targeting to lysosome (GO:0006622) | 2.61465408 |
83 | establishment of protein localization to vacuole (GO:0072666) | 2.61465408 |
84 | protein targeting to vacuole (GO:0006623) | 2.61465408 |
85 | activated T cell proliferation (GO:0050798) | 2.59867408 |
86 | response to peptidoglycan (GO:0032494) | 2.59736330 |
87 | negative regulation of leukocyte mediated immunity (GO:0002704) | 2.59533974 |
88 | negative regulation of amyloid precursor protein catabolic process (GO:1902992) | 2.59523702 |
89 | detection of biotic stimulus (GO:0009595) | 2.58421031 |
90 | regulation of regulatory T cell differentiation (GO:0045589) | 2.57921329 |
91 | T-helper 1 type immune response (GO:0042088) | 2.57855603 |
92 | granulocyte activation (GO:0036230) | 2.57240307 |
93 | regulation of B cell receptor signaling pathway (GO:0050855) | 2.57221433 |
94 | macroautophagy (GO:0016236) | 2.56398753 |
95 | dendritic cell chemotaxis (GO:0002407) | 2.54437308 |
96 | B cell homeostasis (GO:0001782) | 2.52044293 |
97 | positive regulation of interleukin-2 biosynthetic process (GO:0045086) | 2.49873502 |
98 | regulation of B cell differentiation (GO:0045577) | 2.48287536 |
99 | neutrophil activation (GO:0042119) | 2.46716305 |
100 | natural killer cell mediated immunity (GO:0002228) | 2.43731931 |
101 | natural killer cell mediated cytotoxicity (GO:0042267) | 2.43731931 |
102 | positive regulation of cellular amide metabolic process (GO:0034250) | 2.41927383 |
103 | macrophage activation (GO:0042116) | 2.41239178 |
104 | nuclear pore complex assembly (GO:0051292) | 2.41220680 |
105 | positive regulation of interleukin-12 production (GO:0032735) | 2.41182216 |
106 | growth hormone receptor signaling pathway (GO:0060396) | 2.40155709 |
107 | regulation of macrophage cytokine production (GO:0010935) | 2.39916536 |
108 | clathrin coat assembly (GO:0048268) | 2.39738631 |
109 | positive regulation of mRNA catabolic process (GO:0061014) | 2.38802199 |
110 | regulation of gamma-delta T cell activation (GO:0046643) | 2.37999214 |
111 | regulation of gamma-delta T cell differentiation (GO:0045586) | 2.37782471 |
112 | B cell receptor signaling pathway (GO:0050853) | 2.37720364 |
113 | myeloid cell activation involved in immune response (GO:0002275) | 2.35890518 |
114 | interferon-gamma-mediated signaling pathway (GO:0060333) | 2.34335272 |
115 | regulation of T cell tolerance induction (GO:0002664) | 2.33975029 |
116 | lipopolysaccharide-mediated signaling pathway (GO:0031663) | 2.33630937 |
117 | immunoglobulin mediated immune response (GO:0016064) | 2.29249676 |
118 | protein targeting to Golgi (GO:0000042) | 2.28666178 |
119 | histone H3-K36 demethylation (GO:0070544) | 2.27640159 |
120 | regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition | 2.26701496 |
121 | retrograde transport, vesicle recycling within Golgi (GO:0000301) | 2.26487726 |
122 | response to interleukin-15 (GO:0070672) | 2.25361228 |
123 | myeloid dendritic cell differentiation (GO:0043011) | 2.24968055 |
124 | regulation of alpha-beta T cell proliferation (GO:0046640) | 2.22669056 |
125 | B cell proliferation (GO:0042100) | 2.22361122 |
126 | establishment of protein localization to Golgi (GO:0072600) | 2.20908661 |
127 | negative thymic T cell selection (GO:0045060) | 2.19492953 |
128 | regulation of T-helper 1 cell differentiation (GO:0045625) | 2.18354763 |
129 | NLS-bearing protein import into nucleus (GO:0006607) | 2.18294280 |
130 | regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060211) | 2.17870629 |
131 | positive regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060213) | 2.17870629 |
132 | regulation of interferon-beta production (GO:0032648) | 2.16045501 |
133 | regulation of mRNA catabolic process (GO:0061013) | 2.15775896 |
134 | positive regulation of interferon-gamma biosynthetic process (GO:0045078) | 2.15760773 |
135 | positive regulation of erythrocyte differentiation (GO:0045648) | 2.15389119 |
136 | histone mRNA catabolic process (GO:0071044) | 2.14103535 |
137 | cellular response to ethanol (GO:0071361) | 2.14054499 |
138 | corticosteroid receptor signaling pathway (GO:0031958) | 2.12782587 |
139 | microglial cell activation (GO:0001774) | 2.12466954 |
140 | negative T cell selection (GO:0043383) | 2.12377316 |
141 | myeloid dendritic cell activation (GO:0001773) | 2.11395515 |
142 | positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO | 2.11147076 |
143 | regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO:1900151) | 2.11147076 |
144 | T cell migration (GO:0072678) | 2.09811139 |
145 | positive regulation of myeloid leukocyte cytokine production involved in immune response (GO:0061081 | 2.08918142 |
146 | positive regulation of histone deacetylation (GO:0031065) | 2.07723530 |
Rank | Gene Set | Z-score |
---|---|---|
1 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 4.48102355 |
2 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 4.00743941 |
3 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 3.67809633 |
4 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 3.44927256 |
5 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 3.41912855 |
6 | GATA1_22025678_ChIP-Seq_K562_Human | 3.19828259 |
7 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 3.05452672 |
8 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 3.01524089 |
9 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 2.92440148 |
10 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 2.83981919 |
11 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 2.75937007 |
12 | * SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 2.60425686 |
13 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 2.56531150 |
14 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 2.51808365 |
15 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 2.39853710 |
16 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 2.31675866 |
17 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 2.19571965 |
18 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 2.18466918 |
19 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.89996615 |
20 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 1.85968865 |
21 | RUNX_20019798_ChIP-Seq_JUKART_Human | 1.83489959 |
22 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 1.79647280 |
23 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.69096819 |
24 | TP53_16413492_ChIP-PET_HCT116_Human | 1.66726554 |
25 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 1.65057453 |
26 | * FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.61085802 |
27 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.57725151 |
28 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.48760932 |
29 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.44187226 |
30 | SPI1_23547873_ChIP-Seq_NB4_Human | 1.43268598 |
31 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.42353025 |
32 | MYB_26560356_Chip-Seq_TH2_Human | 1.36629411 |
33 | * PU_27001747_Chip-Seq_BMDM_Mouse | 1.36102763 |
34 | NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human | 1.35671333 |
35 | SCL_19346495_ChIP-Seq_HPC-7_Human | 1.34976160 |
36 | * BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.34928355 |
37 | * ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.31826251 |
38 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.31459599 |
39 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 1.30493725 |
40 | * PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.30074579 |
41 | SPI1_23127762_ChIP-Seq_K562_Human | 1.30025708 |
42 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.29458490 |
43 | ZNF217_24962896_ChIP-Seq_MCF-7_Human | 1.28871843 |
44 | * POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.27654899 |
45 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 1.27315531 |
46 | VDR_24787735_ChIP-Seq_THP-1_Human | 1.26883548 |
47 | * CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 1.24872906 |
48 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.24369116 |
49 | * EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.23729785 |
50 | MYB_26560356_Chip-Seq_TH1_Human | 1.23677900 |
51 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 1.21592257 |
52 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 1.21320218 |
53 | * SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.17734729 |
54 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.16173386 |
55 | TCF7_22412390_ChIP-Seq_EML_Mouse | 1.16091181 |
56 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.15345541 |
57 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.13953075 |
58 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.13410495 |
59 | TCF3_18467660_ChIP-ChIP_MESCs_Mouse | 1.13392132 |
60 | NRF2_20460467_ChIP-Seq_MEFs_Mouse | 1.13261404 |
61 | NFE2L2_20460467_ChIP-Seq_MEFs_Mouse | 1.13261404 |
62 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.11251520 |
63 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 1.10700326 |
64 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 1.10251576 |
65 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.08984942 |
66 | BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 1.08844015 |
67 | FOXO3_23340844_ChIP-Seq_DLD1_Human | 1.08776580 |
68 | FLI1_21867929_ChIP-Seq_TH2_Mouse | 1.07189091 |
69 | * NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.06947261 |
70 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 1.06869494 |
71 | RUNX1_17652178_ChIP-ChIP_JURKAT_Human | 1.05714390 |
72 | MAF_26560356_Chip-Seq_TH1_Human | 1.04054406 |
73 | * GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.03616025 |
74 | FOXM1_26456572_ChIP-Seq_MCF-7_Human | 1.02795131 |
75 | * OCT4_21477851_ChIP-Seq_ESCs_Mouse | 1.02239810 |
76 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 1.01559657 |
77 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.01099988 |
78 | * SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 0.99989237 |
79 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 0.99259496 |
80 | GATA2_19941826_ChIP-Seq_K562_Human | 0.99216598 |
81 | FOXA2_19822575_ChIP-Seq_HepG2_Human | 0.99048367 |
82 | TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse | 0.98656034 |
83 | STAT3_23295773_ChIP-Seq_U87_Human | 0.98634639 |
84 | P300_19829295_ChIP-Seq_ESCs_Human | 0.98466476 |
85 | BCAT_22108803_ChIP-Seq_LS180_Human | 0.98250291 |
86 | * SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse | 0.96858548 |
87 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 0.96582911 |
88 | GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.95994927 |
89 | * ESR1_22446102_ChIP-Seq_UTERUS_Mouse | 0.95882709 |
90 | * SUZ12_18555785_Chip-Seq_ESCs_Mouse | 0.95604936 |
91 | FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human | 0.95461286 |
92 | GATA3_26560356_Chip-Seq_TH2_Human | 0.94964812 |
93 | * CRX_20693478_ChIP-Seq_RETINA_Mouse | 0.94551007 |
94 | FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 0.94448545 |
95 | * CMYC_18555785_Chip-Seq_ESCs_Mouse | 0.94143440 |
96 | LXR_22158963_ChIP-Seq_LIVER_Mouse | 0.93931892 |
97 | * E2F1_18555785_Chip-Seq_ESCs_Mouse | 0.93845086 |
98 | CDX2_22108803_ChIP-Seq_LS180_Human | 0.93730535 |
99 | RXR_22108803_ChIP-Seq_LS180_Human | 0.93332871 |
100 | CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse | 0.93238463 |
101 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 0.92258797 |
102 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 0.91440546 |
103 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 0.91321757 |
104 | BRD4_25478319_ChIP-Seq_HGPS_Human | 0.90548414 |
105 | KDM2B_26808549_Chip-Seq_DND41_Human | 0.90375140 |
106 | STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 0.90228380 |
107 | TCF4_23295773_ChIP-Seq_U87_Human | 0.89955177 |
108 | IGF1R_20145208_ChIP-Seq_DFB_Human | 0.89393945 |
109 | TP63_23658742_ChIP-Seq_EP156T_Human | 0.89245487 |
110 | PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse | 0.89063500 |
111 | VDR_24763502_ChIP-Seq_THP-1_Human | 0.89004648 |
112 | GATA1_19941826_ChIP-Seq_K562_Human | 0.88916285 |
113 | AR_25329375_ChIP-Seq_VCAP_Human | 0.88834251 |
114 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 0.88649713 |
115 | DMRT1_23473982_ChIP-Seq_TESTES_Mouse | 0.88389524 |
116 | TAF15_26573619_Chip-Seq_HEK293_Human | 0.88006154 |
117 | CTNNB1_20460455_ChIP-Seq_HCT116_Human | 0.87745334 |
118 | NR1I2_20693526_ChIP-Seq_LIVER_Mouse | 0.87442916 |
119 | * TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 0.87440960 |
120 | * NANOG_18555785_Chip-Seq_ESCs_Mouse | 0.86502614 |
121 | TP53_18474530_ChIP-ChIP_U2OS_Human | 0.85282816 |
122 | PKCTHETA_26484144_Chip-Seq_BREAST_Human | 0.85161580 |
123 | AHR_22903824_ChIP-Seq_MCF-7_Human | 0.82741717 |
124 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 0.82721074 |
125 | SMRT_27268052_Chip-Seq_Bcells_Human | 0.82462866 |
126 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 0.80550337 |
127 | PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.80313622 |
128 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.80107438 |
129 | DROSHA_22980978_ChIP-Seq_HELA_Human | 0.79523179 |
130 | NR3C1_23031785_ChIP-Seq_PC12_Mouse | 0.79364971 |
131 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 0.79012982 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0000569_abnormal_digit_pigmentation | 5.42671751 |
2 | MP0001835_abnormal_antigen_presentation | 3.61156242 |
3 | MP0008057_abnormal_DNA_replication | 3.10895192 |
4 | MP0003300_gastrointestinal_ulcer | 2.86725497 |
5 | MP0003303_peritoneal_inflammation | 2.80988132 |
6 | MP0010307_abnormal_tumor_latency | 2.54268604 |
7 | MP0005075_abnormal_melanosome_morpholog | 2.42989560 |
8 | MP0006082_CNS_inflammation | 2.35074434 |
9 | MP0005076_abnormal_cell_differentiation | 2.23586603 |
10 | MP0001790_abnormal_immune_system | 2.17461886 |
11 | MP0005387_immune_system_phenotype | 2.17461886 |
12 | MP0003436_decreased_susceptibility_to | 2.17415711 |
13 | MP0004510_myositis | 2.16491923 |
14 | MP0005000_abnormal_immune_tolerance | 2.15757081 |
15 | MP0002166_altered_tumor_susceptibility | 2.08208163 |
16 | MP0003787_abnormal_imprinting | 2.07125748 |
17 | MP0002006_tumorigenesis | 2.05281698 |
18 | MP0001800_abnormal_humoral_immune | 2.04962806 |
19 | MP0000685_abnormal_immune_system | 2.00364350 |
20 | MP0008260_abnormal_autophagy | 2.00163149 |
21 | MP0002419_abnormal_innate_immunity | 1.99244153 |
22 | MP0005671_abnormal_response_to | 1.94746711 |
23 | MP0003828_pulmonary_edema | 1.94662619 |
24 | MP0003183_abnormal_peptide_metabolism | 1.94203093 |
25 | MP0004808_abnormal_hematopoietic_stem | 1.93166654 |
26 | MP0005310_abnormal_salivary_gland | 1.91642135 |
27 | MP0002452_abnormal_antigen_presenting | 1.87770772 |
28 | MP0004859_abnormal_synaptic_plasticity | 1.87610637 |
29 | MP0002723_abnormal_immune_serum | 1.77828855 |
30 | MP0009785_altered_susceptibility_to | 1.76255040 |
31 | MP0008877_abnormal_DNA_methylation | 1.75153908 |
32 | MP0003045_fibrosis | 1.70350290 |
33 | MP0005025_abnormal_response_to | 1.68375987 |
34 | MP0005464_abnormal_platelet_physiology | 1.66921980 |
35 | MP0004381_abnormal_hair_follicle | 1.64510407 |
36 | MP0003724_increased_susceptibility_to | 1.63476469 |
37 | MP0001819_abnormal_immune_cell | 1.60939298 |
38 | MP0002148_abnormal_hypersensitivity_rea | 1.60675804 |
39 | MP0002420_abnormal_adaptive_immunity | 1.60481898 |
40 | MP0003656_abnormal_erythrocyte_physiolo | 1.56588599 |
41 | MP0009764_decreased_sensitivity_to | 1.56479967 |
42 | MP0010352_gastrointestinal_tract_polyps | 1.56275001 |
43 | MP0005408_hypopigmentation | 1.55281893 |
44 | MP0002398_abnormal_bone_marrow | 1.53844391 |
45 | MP0003172_abnormal_lysosome_physiology | 1.53429945 |
46 | MP0003075_altered_response_to | 1.52372624 |
47 | MP0001348_abnormal_lacrimal_gland | 1.48405508 |
48 | MP0010234_abnormal_vibrissa_follicle | 1.44675057 |
49 | MP0000604_amyloidosis | 1.42199742 |
50 | MP0005397_hematopoietic_system_phenotyp | 1.41381392 |
51 | MP0001545_abnormal_hematopoietic_system | 1.41381392 |
52 | MP0004947_skin_inflammation | 1.41366629 |
53 | MP0004147_increased_porphyrin_level | 1.39272138 |
54 | MP0001533_abnormal_skeleton_physiology | 1.35938095 |
55 | MP0000716_abnormal_immune_system | 1.33333605 |
56 | MP0003252_abnormal_bile_duct | 1.32020286 |
57 | MP0003091_abnormal_cell_migration | 1.29954809 |
58 | MP0003448_altered_tumor_morphology | 1.28414109 |
59 | MP0003221_abnormal_cardiomyocyte_apopto | 1.28379725 |
60 | MP0001845_abnormal_inflammatory_respons | 1.27003318 |
61 | MP0003705_abnormal_hypodermis_morpholog | 1.25116228 |
62 | MP0009780_abnormal_chondrocyte_physiolo | 1.24141282 |
63 | MP0009278_abnormal_bone_marrow | 1.24022636 |
64 | MP0003690_abnormal_glial_cell | 1.23169402 |
65 | MP0005451_abnormal_body_composition | 1.22139259 |
66 | MP0005166_decreased_susceptibility_to | 1.19481607 |
67 | MP0005058_abnormal_lysosome_morphology | 1.18500517 |
68 | MP0003866_abnormal_defecation | 1.18429013 |
69 | MP0003191_abnormal_cellular_cholesterol | 1.18130650 |
70 | MP0002138_abnormal_hepatobiliary_system | 1.16418360 |
71 | MP0002332_abnormal_exercise_endurance | 1.15222614 |
72 | MP0002139_abnormal_hepatobiliary_system | 1.12185741 |
73 | MP0004484_altered_response_of | 1.11352599 |
74 | MP0002396_abnormal_hematopoietic_system | 1.10256422 |
75 | MP0008961_abnormal_basal_metabolism | 1.08605433 |
76 | MP0000689_abnormal_spleen_morphology | 1.07365400 |
77 | MP0002405_respiratory_system_inflammati | 1.06238357 |
78 | MP0002928_abnormal_bile_duct | 1.03200748 |
79 | MP0002429_abnormal_blood_cell | 1.01241047 |
80 | MP0010155_abnormal_intestine_physiology | 1.00260864 |
81 | MP0001851_eye_inflammation | 1.00132554 |
82 | MP0001853_heart_inflammation | 0.99978951 |
83 | MP0000858_altered_metastatic_potential | 0.99701012 |
84 | MP0002722_abnormal_immune_system | 0.99515341 |
85 | MP0008469_abnormal_protein_level | 0.99044974 |
86 | MP0001873_stomach_inflammation | 0.98113427 |
87 | MP0010329_abnormal_lipoprotein_level | 0.95688200 |
88 | MP0000371_diluted_coat_color | 0.95165520 |
89 | MP0002998_abnormal_bone_remodeling | 0.93709494 |
90 | MP0000427_abnormal_hair_cycle | 0.92767609 |
91 | MP0000465_gastrointestinal_hemorrhage | 0.88144128 |
92 | MP0009763_increased_sensitivity_to | 0.87560497 |
93 | MP0005174_abnormal_tail_pigmentation | 0.85501641 |
94 | MP0010678_abnormal_skin_adnexa | 0.83230133 |
95 | MP0003633_abnormal_nervous_system | 0.83218140 |
96 | MP0004883_abnormal_blood_vessel | 0.83140634 |
97 | MP0001915_intracranial_hemorrhage | 0.82508383 |
98 | MP0004130_abnormal_muscle_cell | 0.82504799 |
99 | MP0000703_abnormal_thymus_morphology | 0.82198818 |
100 | MP0000015_abnormal_ear_pigmentation | 0.82118726 |
101 | MP0000609_abnormal_liver_physiology | 0.81963206 |
102 | MP0005379_endocrine/exocrine_gland_phen | 0.81687376 |
103 | MP0008874_decreased_physiological_sensi | 0.80858838 |
104 | MP0002090_abnormal_vision | 0.80222500 |
105 | MP0002009_preneoplasia | 0.78629185 |
106 | MP0002063_abnormal_learning/memory/cond | 0.77880142 |
107 | MP0006054_spinal_hemorrhage | 0.77424897 |
108 | MP0009046_muscle_twitch | 0.76974908 |
109 | MP0003635_abnormal_synaptic_transmissio | 0.75594539 |
110 | MP0005164_abnormal_response_to | 0.74935881 |
111 | MP0002877_abnormal_melanocyte_morpholog | 0.71858483 |
112 | MP0004811_abnormal_neuron_physiology | 0.71110020 |
113 | MP0002095_abnormal_skin_pigmentation | 0.69948188 |
114 | MP0009333_abnormal_splenocyte_physiolog | 0.67900335 |
115 | MP0003632_abnormal_nervous_system | 0.67772909 |
116 | MP0003763_abnormal_thymus_physiology | 0.66465932 |
117 | MP0005621_abnormal_cell_physiology | 0.64818582 |
118 | MP0005376_homeostasis/metabolism_phenot | 0.63093899 |
119 | MP0003950_abnormal_plasma_membrane | 0.60673080 |
120 | MP0002693_abnormal_pancreas_physiology | 0.60329847 |
121 | MP0002019_abnormal_tumor_incidence | 0.59073236 |
122 | MP0003195_calcinosis | 0.58646901 |
123 | MP0005266_abnormal_metabolism | 0.58123980 |
124 | MP0003646_muscle_fatigue | 0.57164619 |
125 | MP0000249_abnormal_blood_vessel | 0.55626806 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Stomatitis (HP:0010280) | 3.76385375 |
2 | IgM deficiency (HP:0002850) | 3.63661082 |
3 | Eczematoid dermatitis (HP:0000976) | 3.50076969 |
4 | Abnormality of B cell number (HP:0010975) | 3.32084697 |
5 | Recurrent gram-negative bacterial infections (HP:0005420) | 3.27078418 |
6 | Papilledema (HP:0001085) | 3.20645043 |
7 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 3.19966103 |
8 | Abnormality of T cells (HP:0002843) | 3.17737877 |
9 | Retrobulbar optic neuritis (HP:0100654) | 3.15483904 |
10 | Optic neuritis (HP:0100653) | 3.15483904 |
11 | B lymphocytopenia (HP:0010976) | 3.14348560 |
12 | Recurrent abscess formation (HP:0002722) | 3.02115878 |
13 | Recurrent bacterial skin infections (HP:0005406) | 2.95995299 |
14 | Spontaneous hematomas (HP:0007420) | 2.94469304 |
15 | Arterial thrombosis (HP:0004420) | 2.93010466 |
16 | Myocardial infarction (HP:0001658) | 2.92470301 |
17 | Orchitis (HP:0100796) | 2.81797648 |
18 | Macroorchidism (HP:0000053) | 2.81061446 |
19 | Absent frontal sinuses (HP:0002688) | 2.78088075 |
20 | Recurrent viral infections (HP:0004429) | 2.76778441 |
21 | Gastrointestinal infarctions (HP:0005244) | 2.76379854 |
22 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.72708648 |
23 | Autoimmune thrombocytopenia (HP:0001973) | 2.72311882 |
24 | Autoimmune hemolytic anemia (HP:0001890) | 2.70482971 |
25 | Mitral stenosis (HP:0001718) | 2.65956205 |
26 | Leukocytosis (HP:0001974) | 2.63943144 |
27 | Mediastinal lymphadenopathy (HP:0100721) | 2.61712716 |
28 | Myositis (HP:0100614) | 2.60088535 |
29 | Abnormality of T cell physiology (HP:0011840) | 2.54579325 |
30 | Stomach cancer (HP:0012126) | 2.49296140 |
31 | Albinism (HP:0001022) | 2.48902950 |
32 | Disinhibition (HP:0000734) | 2.48875272 |
33 | Encephalitis (HP:0002383) | 2.47958929 |
34 | Recurrent fungal infections (HP:0002841) | 2.47711899 |
35 | Subacute progressive viral hepatitis (HP:0006572) | 2.47636185 |
36 | Inflammation of the large intestine (HP:0002037) | 2.47009454 |
37 | Parkinsonism with favorable response to dopaminergic medication (HP:0002548) | 2.45794007 |
38 | IgA deficiency (HP:0002720) | 2.45602614 |
39 | Eosinophilia (HP:0001880) | 2.44042584 |
40 | IgG deficiency (HP:0004315) | 2.40339578 |
41 | Abnormality of eosinophils (HP:0001879) | 2.38553347 |
42 | Abnormality of the fingertips (HP:0001211) | 2.37281838 |
43 | Fatigue (HP:0012378) | 2.31274924 |
44 | Periodontitis (HP:0000704) | 2.28022552 |
45 | Heterotopia (HP:0002282) | 2.27636040 |
46 | Neoplasm of the tracheobronchial system (HP:0100552) | 2.26073121 |
47 | Hemoptysis (HP:0002105) | 2.25747647 |
48 | Prolonged bleeding time (HP:0003010) | 2.23852523 |
49 | Hematochezia (HP:0002573) | 2.23566740 |
50 | Volvulus (HP:0002580) | 2.20519555 |
51 | Inappropriate behavior (HP:0000719) | 2.19762517 |
52 | Pustule (HP:0200039) | 2.19373354 |
53 | Gastrointestinal inflammation (HP:0004386) | 2.18013149 |
54 | Tetraparesis (HP:0002273) | 2.17560743 |
55 | Chronic otitis media (HP:0000389) | 2.16992441 |
56 | Acanthocytosis (HP:0001927) | 2.16979108 |
57 | Keratoconjunctivitis sicca (HP:0001097) | 2.15366515 |
58 | Slow saccadic eye movements (HP:0000514) | 2.10713526 |
59 | Vasculitis (HP:0002633) | 2.09643037 |
60 | Systemic lupus erythematosus (HP:0002725) | 2.09106878 |
61 | Cellulitis (HP:0100658) | 2.04945909 |
62 | Aplasia/Hypoplasia of the frontal sinuses (HP:0009119) | 2.03285619 |
63 | Severe combined immunodeficiency (HP:0004430) | 2.03011218 |
64 | Ocular albinism (HP:0001107) | 2.02892691 |
65 | Chronic diarrhea (HP:0002028) | 2.02791748 |
66 | Viral hepatitis (HP:0006562) | 2.02666880 |
67 | Recurrent skin infections (HP:0001581) | 2.01661165 |
68 | Gingivitis (HP:0000230) | 2.00140586 |
69 | Granulocytopenia (HP:0001913) | 1.98452964 |
70 | Pulmonary infiltrates (HP:0002113) | 1.97964553 |
71 | Increased cerebral lipofuscin (HP:0011813) | 1.97436187 |
72 | Urticaria (HP:0001025) | 1.95591162 |
73 | Gingival bleeding (HP:0000225) | 1.95432459 |
74 | Keratoconjunctivitis (HP:0001096) | 1.94666816 |
75 | Papillary thyroid carcinoma (HP:0002895) | 1.93717575 |
76 | Lymphopenia (HP:0001888) | 1.93683329 |
77 | Thyroiditis (HP:0100646) | 1.92737145 |
78 | Genetic anticipation (HP:0003743) | 1.92156484 |
79 | Postural instability (HP:0002172) | 1.90690987 |
80 | Narrow palate (HP:0000189) | 1.90336190 |
81 | Recurrent cutaneous fungal infections (HP:0011370) | 1.89866294 |
82 | Chronic mucocutaneous candidiasis (HP:0002728) | 1.89866294 |
83 | Supranuclear gaze palsy (HP:0000605) | 1.89508227 |
84 | Upper motor neuron abnormality (HP:0002127) | 1.88264436 |
85 | Recurrent bronchitis (HP:0002837) | 1.88189948 |
86 | Colitis (HP:0002583) | 1.87673705 |
87 | Complement deficiency (HP:0004431) | 1.87580207 |
88 | Abnormality of macrophages (HP:0004311) | 1.86728786 |
89 | Abnormality of T cell number (HP:0011839) | 1.86310253 |
90 | Generalized hypopigmentation of hair (HP:0011358) | 1.86242748 |
91 | Osteomyelitis (HP:0002754) | 1.86130783 |
92 | T lymphocytopenia (HP:0005403) | 1.85746366 |
93 | Fair hair (HP:0002286) | 1.85346437 |
94 | Enlarged penis (HP:0000040) | 1.84660610 |
95 | Truncal obesity (HP:0001956) | 1.82590723 |
96 | Epistaxis (HP:0000421) | 1.81785801 |
97 | Alveolar cell carcinoma (HP:0006519) | 1.81549069 |
98 | Abnormality of cells of the lymphoid lineage (HP:0012140) | 1.79825939 |
99 | Rhabdomyosarcoma (HP:0002859) | 1.79516745 |
100 | Panhypogammaglobulinemia (HP:0003139) | 1.79255095 |
101 | Gaze-evoked nystagmus (HP:0000640) | 1.78863551 |
102 | Abnormality of the vasculature of the conjunctiva (HP:0008054) | 1.76983952 |
103 | Osteolytic defects of the hand bones (HP:0009699) | 1.75761717 |
104 | Osteolytic defects of the phalanges of the hand (HP:0009771) | 1.75761717 |
105 | Agammaglobulinemia (HP:0004432) | 1.75685498 |
106 | Generalized hypopigmentation (HP:0007513) | 1.74942627 |
107 | Spinal cord lesions (HP:0100561) | 1.73749509 |
108 | Syringomyelia (HP:0003396) | 1.73749509 |
109 | Widely spaced teeth (HP:0000687) | 1.73480260 |
110 | Meningitis (HP:0001287) | 1.73088519 |
111 | Oligodactyly (hands) (HP:0001180) | 1.72907911 |
112 | Focal seizures (HP:0007359) | 1.72653777 |
113 | Striae distensae (HP:0001065) | 1.72610396 |
114 | Anorexia (HP:0002039) | 1.71584700 |
115 | Abnormality of ocular smooth pursuit (HP:0000617) | 1.71413203 |
116 | Abnormality of the peritoneum (HP:0002585) | 1.70499285 |
117 | Keratitis (HP:0000491) | 1.70132672 |
118 | Conjunctival telangiectasia (HP:0000524) | 1.69578444 |
119 | Impaired smooth pursuit (HP:0007772) | 1.69357630 |
120 | Microcytic anemia (HP:0001935) | 1.68957476 |
121 | Poikilocytosis (HP:0004447) | 1.68897076 |
122 | Transitional cell carcinoma of the bladder (HP:0006740) | 1.67783422 |
123 | Cerebral aneurysm (HP:0004944) | 1.67246292 |
124 | Abnormality of the frontal sinuses (HP:0002687) | 1.66808477 |
125 | Increased CSF protein (HP:0002922) | 1.66478530 |
126 | Combined immunodeficiency (HP:0005387) | 1.66158140 |
127 | Hypochromic microcytic anemia (HP:0004840) | 1.65734279 |
128 | Menstrual irregularities (HP:0000858) | 1.65366081 |
129 | Difficulty running (HP:0009046) | 1.64444025 |
130 | Increased neuronal autofluorescent lipopigment (HP:0002074) | 1.64163727 |
131 | Aqueductal stenosis (HP:0002410) | 1.63465345 |
132 | Febrile seizures (HP:0002373) | 1.62768558 |
133 | Cutaneous melanoma (HP:0012056) | 1.61778311 |
134 | Acute myeloid leukemia (HP:0004808) | 1.61450969 |
135 | Thrombophlebitis (HP:0004418) | 1.59946076 |
136 | Chronic sinusitis (HP:0011109) | 1.59875070 |
137 | Glomerulonephritis (HP:0000099) | 1.58392022 |
138 | Drooling (HP:0002307) | 1.57825934 |
139 | Excessive salivation (HP:0003781) | 1.57825934 |
140 | Cerebral inclusion bodies (HP:0100314) | 1.57531497 |
141 | Abnormality of the nasal septum (HP:0000419) | 1.56970034 |
142 | Pulmonary embolism (HP:0002204) | 1.55639500 |
143 | Nasal polyposis (HP:0100582) | 1.55628284 |
144 | Chest pain (HP:0100749) | 1.55511645 |
145 | Protruding tongue (HP:0010808) | 1.54462897 |
146 | Resting tremor (HP:0002322) | 1.54096143 |
147 | Aplasia/Hypoplasia involving the sinuses (HP:0009120) | 1.53135046 |
148 | Abnormality of the common coagulation pathway (HP:0010990) | 1.52985310 |
149 | Thyroid carcinoma (HP:0002890) | 1.51943126 |
150 | Spontaneous abortion (HP:0005268) | 1.50897639 |
151 | Cortical dysplasia (HP:0002539) | 1.50636363 |
Rank | Gene Set | Z-score |
---|---|---|
1 | RIPK4 | 3.30185153 |
2 | CDK12 | 3.17650392 |
3 | MAP3K13 | 2.58700813 |
4 | FRK | 2.56218062 |
5 | MAP3K9 | 2.54126393 |
6 | SCYL2 | 2.45160573 |
7 | JAK1 | 2.43388163 |
8 | MAP3K14 | 2.39757582 |
9 | TYK2 | 2.26400331 |
10 | JAK3 | 2.23278770 |
11 | NLK | 2.11048433 |
12 | FGFR3 | 2.02945637 |
13 | TAOK3 | 1.84859947 |
14 | SIK2 | 1.82224465 |
15 | IRAK1 | 1.73535696 |
16 | MAP3K10 | 1.60974977 |
17 | CAMK1G | 1.60275109 |
18 | NTRK3 | 1.59404575 |
19 | CAMK1D | 1.58192020 |
20 | SGK3 | 1.57946312 |
21 | MAP2K3 | 1.55526175 |
22 | STK3 | 1.54817253 |
23 | MAP4K1 | 1.50990535 |
24 | AKT3 | 1.50874645 |
25 | PIK3CG | 1.49743641 |
26 | IKBKE | 1.48594431 |
27 | YES1 | 1.43252580 |
28 | MAP3K4 | 1.39754909 |
29 | TBK1 | 1.35063247 |
30 | KIT | 1.33581917 |
31 | PLK2 | 1.31700089 |
32 | JAK2 | 1.29616825 |
33 | SYK | 1.24540530 |
34 | SGK2 | 1.24517008 |
35 | RIPK1 | 1.23740589 |
36 | CDK6 | 1.21653909 |
37 | NEK9 | 1.21160201 |
38 | PRPF4B | 1.19948659 |
39 | LATS1 | 1.19158078 |
40 | MAP3K1 | 1.16406248 |
41 | CHUK | 1.12171199 |
42 | MINK1 | 1.11877060 |
43 | TRPM7 | 1.11238595 |
44 | STK24 | 1.07979074 |
45 | NUAK1 | 1.05961232 |
46 | MAP3K2 | 1.05637437 |
47 | DAPK2 | 1.05283546 |
48 | ACVR1B | 1.03747545 |
49 | HCK | 1.03254032 |
50 | FGFR4 | 1.01457014 |
51 | PTK6 | 0.99767568 |
52 | EIF2AK3 | 0.96947548 |
53 | STK4 | 0.96591523 |
54 | TXK | 0.96371358 |
55 | PDGFRB | 0.92285523 |
56 | FES | 0.91852630 |
57 | TRIM28 | 0.91673378 |
58 | CSF1R | 0.91224057 |
59 | TEC | 0.90654802 |
60 | CAMKK1 | 0.90645881 |
61 | KSR2 | 0.89829774 |
62 | IKBKB | 0.89396130 |
63 | NEK6 | 0.89001195 |
64 | RET | 0.88685003 |
65 | PIM1 | 0.88549127 |
66 | PRKCH | 0.84829778 |
67 | ITK | 0.84018326 |
68 | ZAP70 | 0.82358841 |
69 | IRAK2 | 0.81783051 |
70 | PDK1 | 0.81365835 |
71 | BRD4 | 0.78750032 |
72 | CSK | 0.78122265 |
73 | STK10 | 0.78067935 |
74 | CDK9 | 0.77637160 |
75 | MAP3K3 | 0.77336504 |
76 | SGK494 | 0.76825970 |
77 | SGK223 | 0.76825970 |
78 | MAP2K4 | 0.75983177 |
79 | MAP3K12 | 0.75929435 |
80 | EPHA3 | 0.75533988 |
81 | BMX | 0.73723338 |
82 | ALK | 0.71717141 |
83 | MST4 | 0.71101494 |
84 | MAP3K5 | 0.71028743 |
85 | LCK | 0.71021731 |
86 | EGFR | 0.69115307 |
87 | IRAK4 | 0.67724248 |
88 | CDC7 | 0.67465581 |
89 | MATK | 0.63181929 |
90 | STK39 | 0.63129397 |
91 | STK38 | 0.61508690 |
92 | SGK1 | 0.61130678 |
93 | KSR1 | 0.60617443 |
94 | BTK | 0.60261569 |
95 | TAOK1 | 0.59800206 |
96 | DAPK1 | 0.59788507 |
97 | WNK1 | 0.59730253 |
98 | MELK | 0.59544885 |
99 | MAPK11 | 0.59340745 |
100 | OXSR1 | 0.58588465 |
101 | EEF2K | 0.58333194 |
102 | PRKCQ | 0.58112916 |
103 | MARK1 | 0.57402205 |
104 | MARK3 | 0.57205084 |
105 | MAPK7 | 0.56978974 |
106 | ERN1 | 0.55576919 |
107 | ERBB3 | 0.55325447 |
108 | BLK | 0.54858150 |
109 | TGFBR2 | 0.53994874 |
110 | DYRK1A | 0.52797079 |
111 | PAK3 | 0.51985606 |
112 | CAMKK2 | 0.51534025 |
113 | ABL1 | 0.51373219 |
114 | MAP3K6 | 0.50815345 |
115 | GRK6 | 0.50498558 |
116 | FER | 0.50337302 |
117 | BMPR2 | 0.49939729 |
118 | NTRK1 | 0.49353636 |
119 | TNK2 | 0.49240378 |
120 | FYN | 0.48930757 |
121 | MOS | 0.48677466 |
122 | FGR | 0.47627185 |
123 | GRK5 | 0.47490569 |
124 | PTK2B | 0.46956520 |
125 | PRKAA2 | 0.46672517 |
126 | CDK5 | 0.45884943 |
127 | MARK2 | 0.43762552 |
128 | MAPK10 | 0.43419863 |
129 | STK11 | 0.43126623 |
130 | MAP2K7 | 0.41836367 |
131 | PDPK1 | 0.40920108 |
132 | RAF1 | 0.40132817 |
133 | RPS6KB1 | 0.39350110 |
134 | LYN | 0.39241667 |
135 | EPHB1 | 0.38862830 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Leishmaniasis_Homo sapiens_hsa05140 | 1.97857663 |
2 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.90118797 |
3 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 1.86732309 |
4 | Osteoclast differentiation_Homo sapiens_hsa04380 | 1.83967677 |
5 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 1.71342855 |
6 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 1.67455355 |
7 | Tuberculosis_Homo sapiens_hsa05152 | 1.54376191 |
8 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 1.49327939 |
9 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 1.47662874 |
10 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 1.45472919 |
11 | Measles_Homo sapiens_hsa05162 | 1.40506720 |
12 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 1.39313095 |
13 | Influenza A_Homo sapiens_hsa05164 | 1.38634929 |
14 | Pertussis_Homo sapiens_hsa05133 | 1.32229925 |
15 | Toxoplasmosis_Homo sapiens_hsa05145 | 1.29455222 |
16 | TNF signaling pathway_Homo sapiens_hsa04668 | 1.29304444 |
17 | Allograft rejection_Homo sapiens_hsa05330 | 1.29126748 |
18 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 1.29094718 |
19 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.27924287 |
20 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.27814241 |
21 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 1.25005764 |
22 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 1.22640840 |
23 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 1.22613202 |
24 | Renal cell carcinoma_Homo sapiens_hsa05211 | 1.19108102 |
25 | Hepatitis B_Homo sapiens_hsa05161 | 1.18620120 |
26 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 1.16498323 |
27 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.14507114 |
28 | Long-term potentiation_Homo sapiens_hsa04720 | 1.13834906 |
29 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.12119898 |
30 | African trypanosomiasis_Homo sapiens_hsa05143 | 1.12119569 |
31 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 1.11036201 |
32 | Pancreatic cancer_Homo sapiens_hsa05212 | 1.09692375 |
33 | Malaria_Homo sapiens_hsa05144 | 1.08311104 |
34 | Legionellosis_Homo sapiens_hsa05134 | 1.08309430 |
35 | Glioma_Homo sapiens_hsa05214 | 1.08243982 |
36 | Salmonella infection_Homo sapiens_hsa05132 | 1.07531884 |
37 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 1.06241767 |
38 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 1.05746179 |
39 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.04769478 |
40 | Circadian rhythm_Homo sapiens_hsa04710 | 1.02992705 |
41 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.99765375 |
42 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.99134574 |
43 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 0.98529131 |
44 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.98384869 |
45 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.96060234 |
46 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.94929618 |
47 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.92911788 |
48 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.92689171 |
49 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.92645628 |
50 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.91626469 |
51 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.91093897 |
52 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.90067411 |
53 | Prostate cancer_Homo sapiens_hsa05215 | 0.88341941 |
54 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.87997898 |
55 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.87122216 |
56 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.84911837 |
57 | Platelet activation_Homo sapiens_hsa04611 | 0.84426009 |
58 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.82332896 |
59 | Apoptosis_Homo sapiens_hsa04210 | 0.82265763 |
60 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.82154242 |
61 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.81429521 |
62 | Viral myocarditis_Homo sapiens_hsa05416 | 0.81380325 |
63 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.81318221 |
64 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.80297010 |
65 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.80204374 |
66 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.79965758 |
67 | Renin secretion_Homo sapiens_hsa04924 | 0.79352342 |
68 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 0.79040560 |
69 | Amoebiasis_Homo sapiens_hsa05146 | 0.78677951 |
70 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.78437257 |
71 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.76049484 |
72 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.75558055 |
73 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.75440675 |
74 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 0.74286085 |
75 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.73361955 |
76 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.72513422 |
77 | Phagosome_Homo sapiens_hsa04145 | 0.71527569 |
78 | Hepatitis C_Homo sapiens_hsa05160 | 0.71242639 |
79 | Circadian entrainment_Homo sapiens_hsa04713 | 0.71137577 |
80 | Salivary secretion_Homo sapiens_hsa04970 | 0.71131560 |
81 | Prion diseases_Homo sapiens_hsa05020 | 0.70848455 |
82 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.70022896 |
83 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.69796509 |
84 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 0.69184410 |
85 | Olfactory transduction_Homo sapiens_hsa04740 | 0.68956729 |
86 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.68921667 |
87 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.67904375 |
88 | Insulin resistance_Homo sapiens_hsa04931 | 0.67676759 |
89 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.66662726 |
90 | Endometrial cancer_Homo sapiens_hsa05213 | 0.66507615 |
91 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.66187422 |
92 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.65704014 |
93 | Amphetamine addiction_Homo sapiens_hsa05031 | 0.65464078 |
94 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 0.65151054 |
95 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.64765601 |
96 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.64739181 |
97 | Morphine addiction_Homo sapiens_hsa05032 | 0.63797196 |
98 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.62871653 |
99 | Shigellosis_Homo sapiens_hsa05131 | 0.61944322 |
100 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.61393237 |
101 | Gastric acid secretion_Homo sapiens_hsa04971 | 0.60718061 |
102 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.60057901 |
103 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.59676749 |
104 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.59350646 |
105 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 0.59250474 |
106 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.59237073 |
107 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.59105079 |
108 | Lysosome_Homo sapiens_hsa04142 | 0.58943364 |
109 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.58932519 |
110 | ABC transporters_Homo sapiens_hsa02010 | 0.58297452 |
111 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.58166136 |
112 | Lysine degradation_Homo sapiens_hsa00310 | 0.57713117 |
113 | Colorectal cancer_Homo sapiens_hsa05210 | 0.57554359 |
114 | Insulin secretion_Homo sapiens_hsa04911 | 0.57474120 |
115 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.56615821 |
116 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.56475946 |
117 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.55821868 |
118 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.55198314 |
119 | Endocytosis_Homo sapiens_hsa04144 | 0.54078737 |
120 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.53819163 |
121 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.53070729 |
122 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.52034525 |
123 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 0.51740728 |
124 | Thyroid cancer_Homo sapiens_hsa05216 | 0.51213368 |
125 | Long-term depression_Homo sapiens_hsa04730 | 0.49572119 |
126 | HTLV-I infection_Homo sapiens_hsa05166 | 0.48935272 |
127 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.48617564 |
128 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.46891039 |
129 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.43502398 |