VCPKMT

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1DNA deamination (GO:0045006)5.92191157
2ribosomal small subunit assembly (GO:0000028)5.38069430
3regulation of B cell receptor signaling pathway (GO:0050855)4.65684024
4viral transcription (GO:0019083)4.65286430
5translational termination (GO:0006415)4.54715836
6positive regulation of gamma-delta T cell activation (GO:0046645)4.52499948
7DNA strand elongation involved in DNA replication (GO:0006271)4.50539606
8telomere maintenance via semi-conservative replication (GO:0032201)4.35761336
9translational elongation (GO:0006414)4.33340781
10formation of translation preinitiation complex (GO:0001731)4.32823564
11positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)4.29581118
12DNA strand elongation (GO:0022616)4.25787853
13maturation of SSU-rRNA (GO:0030490)4.20751712
14SRP-dependent cotranslational protein targeting to membrane (GO:0006614)4.07202335
15nucleobase biosynthetic process (GO:0046112)3.97612302
16negative regulation of leukocyte mediated cytotoxicity (GO:0001911)3.95540510
17negative regulation of cell killing (GO:0031342)3.95540510
18DNA replication initiation (GO:0006270)3.93806923
19protein targeting to ER (GO:0045047)3.93408021
20cotranslational protein targeting to membrane (GO:0006613)3.93165320
21translational initiation (GO:0006413)3.90557955
22ribosomal small subunit biogenesis (GO:0042274)3.83861258
23telomere maintenance via recombination (GO:0000722)3.80927202
24purine nucleobase biosynthetic process (GO:0009113)3.79612648
25ribosomal large subunit biogenesis (GO:0042273)3.77484818
26nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.76687349
27antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G3.76489007
28protein localization to endoplasmic reticulum (GO:0070972)3.74991118
29establishment of protein localization to endoplasmic reticulum (GO:0072599)3.71878968
30proteasome assembly (GO:0043248)3.71464708
31ribosome biogenesis (GO:0042254)3.70375367
32ribonucleoprotein complex biogenesis (GO:0022613)3.70159350
33folic acid-containing compound biosynthetic process (GO:0009396)3.68245829
34viral life cycle (GO:0019058)3.66154198
35DNA unwinding involved in DNA replication (GO:0006268)3.60974747
36deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.60193254
37pseudouridine synthesis (GO:0001522)3.54446530
38cellular protein complex disassembly (GO:0043624)3.53835158
39telomere maintenance via telomere lengthening (GO:0010833)3.52105840
40ribosome assembly (GO:0042255)3.47983355
41negative regulation of T-helper cell differentiation (GO:0045623)3.43875973
42negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371)3.43875973
43mitotic recombination (GO:0006312)3.42981376
44positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)3.42714421
45rRNA processing (GO:0006364)3.36141240
46negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.32202783
47negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515)3.31886781
48regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)3.30746406
49translation (GO:0006412)3.30483637
50negative regulation of interleukin-12 production (GO:0032695)3.26436449
51modulation by symbiont of host defense response (GO:0052031)3.26163248
52modulation by organism of immune response of other organism involved in symbiotic interaction (GO:003.26163248
53modulation by organism of defense response of other organism involved in symbiotic interaction (GO:03.26163248
54positive regulation by organism of defense response of other organism involved in symbiotic interact3.26163248
55modulation by symbiont of host immune response (GO:0052553)3.26163248
56positive regulation by symbiont of host defense response (GO:0052509)3.26163248
57exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.24922935
58B cell receptor signaling pathway (GO:0050853)3.24764475
59response to interleukin-15 (GO:0070672)3.24248541
60DNA replication checkpoint (GO:0000076)3.23837063
61neutrophil activation involved in immune response (GO:0002283)3.22987802
62rRNA metabolic process (GO:0016072)3.22338087
63IMP biosynthetic process (GO:0006188)3.20321789
64regulation of gamma-delta T cell activation (GO:0046643)3.18246639
65DNA replication-dependent nucleosome assembly (GO:0006335)3.17219221
66DNA replication-dependent nucleosome organization (GO:0034723)3.17219221
67spliceosomal snRNP assembly (GO:0000387)3.15661040
68protein complex disassembly (GO:0043241)3.14986095
69neutrophil activation (GO:0042119)3.14302091
70regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.12157598
71anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.11483989
72mitotic nuclear envelope disassembly (GO:0007077)3.10366389
73positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.10336778
74nuclear-transcribed mRNA catabolic process (GO:0000956)3.10177185
75T cell migration (GO:0072678)3.10128098
76rRNA modification (GO:0000154)3.09394877
77negative regulation of RNA splicing (GO:0033119)3.09179284
78negative regulation of B cell proliferation (GO:0030889)3.09171144
79regulation of regulatory T cell differentiation (GO:0045589)3.08811539
80mitotic metaphase plate congression (GO:0007080)3.05497869
81termination of RNA polymerase III transcription (GO:0006386)3.05094690
82transcription elongation from RNA polymerase III promoter (GO:0006385)3.05094690
83positive regulation of interleukin-2 biosynthetic process (GO:0045086)3.05034653
84antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:3.04847833
85IMP metabolic process (GO:0046040)3.04817214
86nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.04224561
87cellular response to interleukin-15 (GO:0071350)3.04150822
88negative regulation of mRNA splicing, via spliceosome (GO:0048025)3.04124989
89cellular component biogenesis (GO:0044085)3.02200467
90DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:003.01974089
91histone mRNA catabolic process (GO:0071044)3.01691251
92regulation of B cell differentiation (GO:0045577)3.00708285
93macromolecular complex disassembly (GO:0032984)3.00598375
94nucleotide-excision repair, DNA gap filling (GO:0006297)3.00485844
95regulation of antigen receptor-mediated signaling pathway (GO:0050854)2.99962484
96signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)2.98308278
97intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)2.98308278
98negative regulation of ubiquitin-protein transferase activity (GO:0051444)2.98240034
99negative regulation of ligase activity (GO:0051352)2.98240034
100respiratory burst (GO:0045730)2.96101974
101signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)2.94552656
102signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)2.94552656
103signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)2.94552656
104mRNA catabolic process (GO:0006402)2.93049404
105positive T cell selection (GO:0043368)2.92847481
106CENP-A containing nucleosome assembly (GO:0034080)2.92195592
107nucleobase-containing small molecule interconversion (GO:0015949)2.91988492
108nuclear envelope disassembly (GO:0051081)2.90657155
109membrane disassembly (GO:0030397)2.90657155
110maturation of 5.8S rRNA (GO:0000460)2.89964796
111antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590)2.89036847
112signal transduction involved in DNA integrity checkpoint (GO:0072401)2.88972192
113signal transduction involved in DNA damage checkpoint (GO:0072422)2.88972192
114regulation of protein heterodimerization activity (GO:0043497)2.87611744
115granulocyte activation (GO:0036230)2.87519839
116antigen processing and presentation of endogenous antigen (GO:0019883)2.87434720
117detection of other organism (GO:0098543)2.87238174
118transcription-coupled nucleotide-excision repair (GO:0006283)2.86717049
119negative regulation of lymphocyte mediated immunity (GO:0002707)2.86362136
120G1/S transition of mitotic cell cycle (GO:0000082)2.86013101
121cell cycle G1/S phase transition (GO:0044843)2.86013101
122chromatin remodeling at centromere (GO:0031055)2.85798880
123RNA catabolic process (GO:0006401)2.85753020
124regulation of gamma-delta T cell differentiation (GO:0045586)2.85580873
125histone-serine phosphorylation (GO:0035404)2.85422364
126deoxyribonucleotide biosynthetic process (GO:0009263)2.84212221
127protein localization to kinetochore (GO:0034501)2.83830852
128signal transduction involved in cell cycle checkpoint (GO:0072395)2.83014584
129regulation of cellular amino acid metabolic process (GO:0006521)2.83013123
130deoxyribose phosphate biosynthetic process (GO:0046385)2.82814182
1312-deoxyribonucleotide biosynthetic process (GO:0009265)2.82814182
132pteridine-containing compound biosynthetic process (GO:0042559)2.80921516
133immunoglobulin mediated immune response (GO:0016064)2.80683773
134B cell mediated immunity (GO:0019724)2.80364747
135metaphase plate congression (GO:0051310)2.79315232
136negative T cell selection (GO:0043383)2.78734277
137establishment of integrated proviral latency (GO:0075713)2.76975039
138viral mRNA export from host cell nucleus (GO:0046784)2.75826425
139protein deneddylation (GO:0000338)2.75321985
140somatic diversification of immune receptors via somatic mutation (GO:0002566)2.74699474
141somatic hypermutation of immunoglobulin genes (GO:0016446)2.74699474
142positive regulation of granulocyte differentiation (GO:0030854)2.73928408
143production of molecular mediator involved in inflammatory response (GO:0002532)2.73715186
144positive thymic T cell selection (GO:0045059)2.72203412
145regulation of alpha-beta T cell proliferation (GO:0046640)2.71984219
146regulation of ER to Golgi vesicle-mediated transport (GO:0060628)2.71900580
147neural tube formation (GO:0001841)2.70043183
148T cell homeostasis (GO:0043029)2.69023485
149detection of bacterium (GO:0016045)2.68917439
150histone mRNA metabolic process (GO:0008334)2.67133077
151cellular extravasation (GO:0045123)2.66326383
152negative thymic T cell selection (GO:0045060)2.66323938
153negative regulation of adaptive immune response based on somatic recombination of immune receptors b2.63849868
154DNA demethylation (GO:0080111)2.62404891
155negative regulation of T cell mediated immunity (GO:0002710)2.60321486
156defense response to protozoan (GO:0042832)2.60086377
157regulation of nitric-oxide synthase biosynthetic process (GO:0051769)2.59773916
158response to peptidoglycan (GO:0032494)2.59686037
159neutrophil mediated immunity (GO:0002446)2.58598254
160positive regulation of B cell differentiation (GO:0045579)2.57638055
161regulation of interferon-beta biosynthetic process (GO:0045357)2.57220888
162regulation of translation in response to stress (GO:0043555)2.54616425
163positive regulation of alpha-beta T cell proliferation (GO:0046641)2.54457418
164myeloid cell activation involved in immune response (GO:0002275)2.54070256
165leukocyte aggregation (GO:0070486)2.53963246
166transcription from mitochondrial promoter (GO:0006390)2.53055083
167establishment of protein localization to mitochondrial membrane (GO:0090151)2.52875003
168positive regulation of protein homooligomerization (GO:0032464)2.51344650
169regulation of germinal center formation (GO:0002634)2.51308592
170negative regulation of adaptive immune response (GO:0002820)2.50033540
171microglial cell activation (GO:0001774)2.48713071
172negative regulation of leukocyte mediated immunity (GO:0002704)2.47765599
173T cell selection (GO:0045058)2.45420426
174dendritic cell migration (GO:0036336)2.44980696
175mast cell activation (GO:0045576)2.44803845
176antigen receptor-mediated signaling pathway (GO:0050851)2.44797178
177positive regulation of interleukin-2 production (GO:0032743)2.44319170
178positive regulation of toll-like receptor signaling pathway (GO:0034123)2.44192127
179regulation of CD4-positive, alpha-beta T cell activation (GO:2000514)2.44079039
180interferon-gamma-mediated signaling pathway (GO:0060333)2.43191768
181antigen processing and presentation of endogenous peptide antigen (GO:0002483)2.41311744
182regulation of T cell receptor signaling pathway (GO:0050856)2.41297373
183interferon-gamma production (GO:0032609)2.40539430
184positive regulation of interferon-alpha production (GO:0032727)2.39642070
185regulation of T-helper 1 cell differentiation (GO:0045625)2.39342159
186detection of external biotic stimulus (GO:0098581)2.38519711
187B cell homeostasis (GO:0001782)2.38175624
188leukocyte degranulation (GO:0043299)2.35718186
189dendritic cell chemotaxis (GO:0002407)2.35343318
190macrophage activation involved in immune response (GO:0002281)2.34952075
191negative regulation of B cell activation (GO:0050869)2.34905168
192regulation of interferon-alpha production (GO:0032647)2.33755376
193histamine secretion (GO:0001821)2.33299182
194lymphocyte homeostasis (GO:0002260)2.33291974
195regulation of B cell proliferation (GO:0030888)2.33108051
196response to host immune response (GO:0052572)2.32836517
197response to immune response of other organism involved in symbiotic interaction (GO:0052564)2.32836517

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human6.62433299
2EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse4.33046818
3MYC_18555785_ChIP-Seq_MESCs_Mouse4.24968230
4FOXP3_17237761_ChIP-ChIP_TREG_Mouse3.86792372
5KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.01607350
6IRF8_21731497_ChIP-ChIP_J774_Mouse2.96114558
7STAT6_20620947_ChIP-Seq_CD4_POS_T_Human2.94933202
8JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.92609637
9GABP_17652178_ChIP-ChIP_JURKAT_Human2.92574793
10BP1_19119308_ChIP-ChIP_Hs578T_Human2.88666844
11MYC_18358816_ChIP-ChIP_MESCs_Mouse2.87999558
12EST1_17652178_ChIP-ChIP_JURKAT_Human2.79673236
13ETS1_20019798_ChIP-Seq_JURKAT_Human2.76142852
14MYC_19079543_ChIP-ChIP_MESCs_Mouse2.70881209
15E2F4_17652178_ChIP-ChIP_JURKAT_Human2.65618312
16MYC_19030024_ChIP-ChIP_MESCs_Mouse2.65468852
17NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.44154116
18HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.44008670
19CREB1_15753290_ChIP-ChIP_HEK293T_Human2.43739171
20FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.32186398
21FOXM1_23109430_ChIP-Seq_U2OS_Human2.31259731
22XRN2_22483619_ChIP-Seq_HELA_Human2.30309249
23ELF1_17652178_ChIP-ChIP_JURKAT_Human2.29777872
24SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.29204864
25VDR_23849224_ChIP-Seq_CD4+_Human2.26164137
26NELFA_20434984_ChIP-Seq_ESCs_Mouse2.18347140
27TAL1_20887958_ChIP-Seq_HPC-7_Mouse2.13014873
28MYC_22102868_ChIP-Seq_BL_Human2.08037415
29E2F1_18555785_ChIP-Seq_MESCs_Mouse2.04875756
30DCP1A_22483619_ChIP-Seq_HELA_Human2.03711421
31GABP_19822575_ChIP-Seq_HepG2_Human2.01553773
32STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.97387723
33CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.96669664
34FOXP3_21729870_ChIP-Seq_TREG_Human1.94133688
35BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.93333140
36FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.88091108
37SALL1_21062744_ChIP-ChIP_HESCs_Human1.87642959
38RUNX_20019798_ChIP-Seq_JUKART_Human1.83269927
39IRF8_27001747_Chip-Seq_BMDM_Mouse1.82847514
40ZNF274_21170338_ChIP-Seq_K562_Hela1.81741600
41THAP11_20581084_ChIP-Seq_MESCs_Mouse1.80594924
42SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.75849484
43HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.75662842
44ZFX_18555785_ChIP-Seq_MESCs_Mouse1.69056116
45SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.68739672
46HOXB4_20404135_ChIP-ChIP_EML_Mouse1.68601554
47TTF2_22483619_ChIP-Seq_HELA_Human1.67734820
48E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.64926859
49FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.63823254
50E2F1_21310950_ChIP-Seq_MCF-7_Human1.63104539
51MYCN_18555785_ChIP-Seq_MESCs_Mouse1.62781092
52GATA3_27048872_Chip-Seq_THYMUS_Human1.61301482
53ERG_20887958_ChIP-Seq_HPC-7_Mouse1.60890961
54POU3F2_20337985_ChIP-ChIP_501MEL_Human1.60546886
55PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.60332418
56ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.57514729
57SRF_21415370_ChIP-Seq_HL-1_Mouse1.56212637
58GATA3_26560356_Chip-Seq_TH2_Human1.55151397
59POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.54957155
60NOTCH1_21737748_ChIP-Seq_TLL_Human1.53727506
61MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.53305143
62EGR1_19374776_ChIP-ChIP_THP-1_Human1.52087795
63SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.51440162
64FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.50885857
65CIITA_25753668_ChIP-Seq_RAJI_Human1.50619147
66MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.49804085
67YY1_21170310_ChIP-Seq_MESCs_Mouse1.48794028
68SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.47078764
69VDR_21846776_ChIP-Seq_THP-1_Human1.45014958
70AR_21909140_ChIP-Seq_LNCAP_Human1.43283347
71ELK1_19687146_ChIP-ChIP_HELA_Human1.43100605
72NANOG_18555785_ChIP-Seq_MESCs_Mouse1.41230046
73NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.38323531
74FLI1_27457419_Chip-Seq_LIVER_Mouse1.35878754
75IRF1_19129219_ChIP-ChIP_H3396_Human1.33905493
76RUNX1_17652178_ChIP-ChIP_JURKAT_Human1.33553055
77CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.32488194
78ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.31871746
79SMAD_19615063_ChIP-ChIP_OVARY_Human1.31645437
80SPI1_23547873_ChIP-Seq_NB4_Human1.29459565
81RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.29235553
82GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.28484908
83IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.28354839
84IGF1R_20145208_ChIP-Seq_DFB_Human1.27498432
85YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.26066879
86KDM5A_27292631_Chip-Seq_BREAST_Human1.22688008
87RBPJ_22232070_ChIP-Seq_NCS_Mouse1.20840032
88MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.20212026
89KLF4_18555785_ChIP-Seq_MESCs_Mouse1.19530900
90TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.19315629
91TFEB_21752829_ChIP-Seq_HELA_Human1.18827766
92STAT3_1855785_ChIP-Seq_MESCs_Mouse1.18518127
93DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.18051290
94TP63_19390658_ChIP-ChIP_HaCaT_Human1.17696360
95TAF15_26573619_Chip-Seq_HEK293_Human1.16347361
96IRF8_22096565_ChIP-ChIP_GC-B_Human1.15928592
97CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.15788334
98EWS_26573619_Chip-Seq_HEK293_Human1.15718196
99PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.14479238
100E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.11961947
101STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.09942266
102STAT4_19710469_ChIP-ChIP_TH1__Mouse1.09806445
103TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.08957305
104CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.07373645
105VDR_22108803_ChIP-Seq_LS180_Human1.04907737
106GATA1_22383799_ChIP-Seq_G1ME_Mouse1.04497022
107FUS_26573619_Chip-Seq_HEK293_Human1.03160507
108MYB_21317192_ChIP-Seq_ERMYB_Mouse1.02022228
109GATA3_26560356_Chip-Seq_TH1_Human1.01799751
110BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.99013353
111MEIS1_20887958_ChIP-Seq_HPC-7_Mouse0.97360058
112HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.96424415
113ER_23166858_ChIP-Seq_MCF-7_Human0.96244114
114UTX_26944678_Chip-Seq_JUKART_Human0.94982681
115ELK1_22589737_ChIP-Seq_MCF10A_Human0.94742645
116CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.94722344
117SALL4_22934838_ChIP-ChIP_CD34+_Human0.94288977
118PCGF2_27294783_Chip-Seq_ESCs_Mouse0.94131816
119MYB_26560356_Chip-Seq_TH2_Human0.93920605
120MYCN_21190229_ChIP-Seq_SHEP-21N_Human0.93731734
121POU5F1_18700969_ChIP-ChIP_MESCs_Mouse0.93320973
122CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human0.92455444
123MYC_18940864_ChIP-ChIP_HL60_Human0.90554503
124MYB_26560356_Chip-Seq_TH1_Human0.89977935
125KDM5B_21448134_ChIP-Seq_MESCs_Mouse0.89956987
126RUNX1_22412390_ChIP-Seq_EML_Mouse0.89395227
127FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.89285220
128MAF_26560356_Chip-Seq_TH1_Human0.88053443
129CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.88035201
130PADI4_21655091_ChIP-ChIP_MCF-7_Human0.86999445
131CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.86871000
132MAF_26560356_Chip-Seq_TH2_Human0.86857827
133POU5F1_18358816_ChIP-ChIP_MESCs_Mouse0.86265699
134TP53_22573176_ChIP-Seq_HFKS_Human0.85823074
135CEBPB_23403033_ChIP-Seq_LIVER_Mouse0.81651687
136NFE2_27457419_Chip-Seq_LIVER_Mouse0.80531021
137SCL_19346495_ChIP-Seq_HPC-7_Human0.78612806
138EZH2_27294783_Chip-Seq_NPCs_Mouse0.78526857

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching4.92411841
2MP0004957_abnormal_blastocyst_morpholog4.10775072
3MP0010094_abnormal_chromosome_stability3.70744271
4MP0003111_abnormal_nucleus_morphology3.39437293
5MP0003077_abnormal_cell_cycle3.29295328
6MP0002396_abnormal_hematopoietic_system3.24909377
7MP0003724_increased_susceptibility_to3.20428612
8MP0008058_abnormal_DNA_repair2.73615300
9MP0003787_abnormal_imprinting2.53994909
10MP0008007_abnormal_cellular_replicative2.52257740
11MP0000490_abnormal_crypts_of2.29874215
12MP0009333_abnormal_splenocyte_physiolog2.28202553
13MP0003763_abnormal_thymus_physiology2.21684296
14MP0001835_abnormal_antigen_presentation2.20645048
15MP0008057_abnormal_DNA_replication2.19110330
16MP0003806_abnormal_nucleotide_metabolis2.15552766
17MP0004808_abnormal_hematopoietic_stem2.13591439
18MP0002277_abnormal_respiratory_mucosa2.01776081
19MP0002398_abnormal_bone_marrow2.01197543
20MP0008932_abnormal_embryonic_tissue1.97708988
21MP0006054_spinal_hemorrhage1.95983352
22MP0005671_abnormal_response_to1.94089760
23MP0010352_gastrointestinal_tract_polyps1.93027878
24MP0000685_abnormal_immune_system1.90410565
25MP0002722_abnormal_immune_system1.86339955
26MP0000689_abnormal_spleen_morphology1.85414057
27MP0001545_abnormal_hematopoietic_system1.84817338
28MP0005397_hematopoietic_system_phenotyp1.84817338
29MP0009785_altered_susceptibility_to1.81470188
30MP0000350_abnormal_cell_proliferation1.77313392
31MP0001730_embryonic_growth_arrest1.72301254
32MP0004147_increased_porphyrin_level1.72039312
33MP0003786_premature_aging1.71763721
34MP0002019_abnormal_tumor_incidence1.66719388
35MP0003303_peritoneal_inflammation1.65928606
36MP0000703_abnormal_thymus_morphology1.63768567
37MP0010307_abnormal_tumor_latency1.63305871
38MP0006082_CNS_inflammation1.59420223
39MP0000313_abnormal_cell_death1.58511350
40MP0001800_abnormal_humoral_immune1.58420542
41MP0002429_abnormal_blood_cell1.57070433
42MP0009764_decreased_sensitivity_to1.55134886
43MP0000716_abnormal_immune_system1.52909500
44MP0009697_abnormal_copulation1.51236794
45MP0003186_abnormal_redox_activity1.50654930
46MP0002420_abnormal_adaptive_immunity1.49778073
47MP0001853_heart_inflammation1.49246322
48MP0001819_abnormal_immune_cell1.47222927
49MP0008877_abnormal_DNA_methylation1.46123630
50MP0006036_abnormal_mitochondrial_physio1.43767800
51MP0002723_abnormal_immune_serum1.43532451
52MP0003123_paternal_imprinting1.42090062
53MP0003656_abnormal_erythrocyte_physiolo1.41388026
54MP0008260_abnormal_autophagy1.41020130
55MP0002452_abnormal_antigen_presenting1.40590577
56MP0005025_abnormal_response_to1.40292386
57MP0008995_early_reproductive_senescence1.36768356
58MP0002080_prenatal_lethality1.36614350
59MP0000858_altered_metastatic_potential1.35710551
60MP0002928_abnormal_bile_duct1.35068922
61MP0000358_abnormal_cell_content/1.34718024
62MP0001188_hyperpigmentation1.33815590
63MP0005000_abnormal_immune_tolerance1.33256325
64MP0005310_abnormal_salivary_gland1.32770368
65MP0009379_abnormal_foot_pigmentation1.31129974
66MP0002009_preneoplasia1.31084960
67MP0001697_abnormal_embryo_size1.30262807
68MP0005464_abnormal_platelet_physiology1.24661476
69MP0006035_abnormal_mitochondrial_morpho1.23018951
70MP0002166_altered_tumor_susceptibility1.22058721
71MP0002405_respiratory_system_inflammati1.21850970
72MP0010155_abnormal_intestine_physiology1.20137048
73MP0004381_abnormal_hair_follicle1.19620412
74MP0003121_genomic_imprinting1.15031062
75MP0003172_abnormal_lysosome_physiology1.14534132
76MP0002132_abnormal_respiratory_system1.14135233
77MP0003866_abnormal_defecation1.13491873
78MP0003436_decreased_susceptibility_to1.06863032
79MP0002006_tumorigenesis1.06510906
80MP0005075_abnormal_melanosome_morpholog1.06229329
81MP0005380_embryogenesis_phenotype1.04129331
82MP0001672_abnormal_embryogenesis/_devel1.04129331
83MP0001873_stomach_inflammation1.03479425
84MP0008961_abnormal_basal_metabolism1.01713000
85MP0001529_abnormal_vocalization0.99051754
86MP0003984_embryonic_growth_retardation0.98820697
87MP0000465_gastrointestinal_hemorrhage0.98543743
88MP0001845_abnormal_inflammatory_respons0.97358908
89MP0004947_skin_inflammation0.97255855
90MP0002095_abnormal_skin_pigmentation0.96515551
91MP0002088_abnormal_embryonic_growth/wei0.94759689
92MP0000569_abnormal_digit_pigmentation0.94153017
93MP0002086_abnormal_extraembryonic_tissu0.94002996
94MP0003221_abnormal_cardiomyocyte_apopto0.92785490
95MP0005174_abnormal_tail_pigmentation0.92248697
96MP0001790_abnormal_immune_system0.91759717
97MP0005387_immune_system_phenotype0.91759717
98MP0005023_abnormal_wound_healing0.90003380
99MP0008469_abnormal_protein_level0.89743389
100MP0000477_abnormal_intestine_morphology0.87466206
101MP0003567_abnormal_fetal_cardiomyocyte0.87127760
102MP0004883_abnormal_blood_vessel0.87057229
103MP0002419_abnormal_innate_immunity0.85933923
104MP0005084_abnormal_gallbladder_morpholo0.85113229
105MP0003718_maternal_effect0.83685003
106MP0001533_abnormal_skeleton_physiology0.82951701
107MP0002085_abnormal_embryonic_tissue0.82438694
108MP0009765_abnormal_xenobiotic_induced0.81839754
109MP0002148_abnormal_hypersensitivity_rea0.80735892
110MP0000598_abnormal_liver_morphology0.79255077
111MP0002210_abnormal_sex_determination0.79226286
112MP0001764_abnormal_homeostasis0.77747112
113MP0001929_abnormal_gametogenesis0.76582509
114MP0001145_abnormal_male_reproductive0.75485205
115MP0002332_abnormal_exercise_endurance0.74759818
116MP0005384_cellular_phenotype0.74605460
117MP0001986_abnormal_taste_sensitivity0.72847700
118MP0004197_abnormal_fetal_growth/weight/0.72263926
119MP0004484_altered_response_of0.72213874
120MP0002822_catalepsy0.71913859
121MP0000516_abnormal_urinary_system0.71359951
122MP0005367_renal/urinary_system_phenotyp0.71359951
123MP0001119_abnormal_female_reproductive0.70648815
124MP0003943_abnormal_hepatobiliary_system0.70564240
125MP0008873_increased_physiological_sensi0.70462675
126MP0002837_dystrophic_cardiac_calcinosis0.70242771
127MP0000015_abnormal_ear_pigmentation0.69965995
128MP0002084_abnormal_developmental_patter0.69318790
129MP0003191_abnormal_cellular_cholesterol0.69079736
130MP0000678_abnormal_parathyroid_gland0.68823867
131MP0005266_abnormal_metabolism0.68072190
132MP0008872_abnormal_physiological_respon0.67634149
133MP0002653_abnormal_ependyma_morphology0.67468012
134MP0003300_gastrointestinal_ulcer0.67427329
135MP0001191_abnormal_skin_condition0.66958741
136MP0009763_increased_sensitivity_to0.66785330
137MP0005376_homeostasis/metabolism_phenot0.66739101
138MP0003448_altered_tumor_morphology0.66038764
139MP0001348_abnormal_lacrimal_gland0.64116260

Predicted human phenotypes

RankGene SetZ-score
1Abnormal number of erythroid precursors (HP:0012131)6.00954471
2Abnormality of cells of the erythroid lineage (HP:0012130)5.86390661
3Birth length less than 3rd percentile (HP:0003561)4.33224217
4Stomatitis (HP:0010280)4.30083805
5Aplastic anemia (HP:0001915)4.26390913
6Reticulocytopenia (HP:0001896)4.02619840
7Panhypogammaglobulinemia (HP:0003139)3.83485457
8Abnormal delayed hypersensitivity skin test (HP:0002963)3.70553935
9Thrombocytosis (HP:0001894)3.59147248
10Recurrent bacterial skin infections (HP:0005406)3.47336782
11Colon cancer (HP:0003003)3.46099649
12Pallor (HP:0000980)3.36836457
13Oral leukoplakia (HP:0002745)3.34025712
14Recurrent abscess formation (HP:0002722)3.31250531
15Abnormality of the heme biosynthetic pathway (HP:0010472)3.30649066
16IgM deficiency (HP:0002850)3.29956198
17Optic neuritis (HP:0100653)3.23093157
18Retrobulbar optic neuritis (HP:0100654)3.23093157
19Abnormal activity of mitochondrial respiratory chain (HP:0011922)3.22664185
20Decreased activity of mitochondrial respiratory chain (HP:0008972)3.22664185
21Degeneration of anterior horn cells (HP:0002398)3.22110846
22Abnormality of the anterior horn cell (HP:0006802)3.22110846
23Reduced antithrombin III activity (HP:0001976)3.21628125
24Encephalitis (HP:0002383)3.14333076
25Microretrognathia (HP:0000308)3.13962310
26Type I transferrin isoform profile (HP:0003642)3.12431658
27Selective tooth agenesis (HP:0001592)3.08011713
28Meningitis (HP:0001287)3.00598056
29Microvesicular hepatic steatosis (HP:0001414)2.98863717
30Severe combined immunodeficiency (HP:0004430)2.96924548
31Progressive muscle weakness (HP:0003323)2.90156979
32Recurrent fungal infections (HP:0002841)2.89292718
33Macrocytic anemia (HP:0001972)2.84946337
34Hepatocellular necrosis (HP:0001404)2.77196245
35Elevated erythrocyte sedimentation rate (HP:0003565)2.74181028
36Multiple enchondromatosis (HP:0005701)2.73972904
37Abnormality of DNA repair (HP:0003254)2.73022251
38Orchitis (HP:0100796)2.72774494
39Acute hepatic failure (HP:0006554)2.71775487
40Recurrent cutaneous fungal infections (HP:0011370)2.71744248
41Chronic mucocutaneous candidiasis (HP:0002728)2.71744248
42Keratoconjunctivitis sicca (HP:0001097)2.71232267
43Increased serum lactate (HP:0002151)2.69299925
44Vasculitis (HP:0002633)2.69231386
45Muscle fiber atrophy (HP:0100295)2.66207234
46Type 2 muscle fiber atrophy (HP:0003554)2.65754167
47Mediastinal lymphadenopathy (HP:0100721)2.62427688
48Agnosia (HP:0010524)2.62005937
49Self-mutilation (HP:0000742)2.59638786
50B lymphocytopenia (HP:0010976)2.54234556
51Hepatic necrosis (HP:0002605)2.52461427
52Eczematoid dermatitis (HP:0000976)2.51069103
53Abnormality of T cell physiology (HP:0011840)2.50145794
54Agammaglobulinemia (HP:0004432)2.49758995
55Recurrent skin infections (HP:0001581)2.49271448
56Rough bone trabeculation (HP:0100670)2.48667782
57Keratoconjunctivitis (HP:0001096)2.48078593
58Thyroiditis (HP:0100646)2.47553676
59Combined immunodeficiency (HP:0005387)2.46693922
60Abnormality of macrophages (HP:0004311)2.44993780
61Petechiae (HP:0000967)2.44842656
62Gastrointestinal infarctions (HP:0005244)2.43016791
63Abnormality of T cells (HP:0002843)2.42339455
64Abnormality of B cell number (HP:0010975)2.41932459
65Overlapping toe (HP:0001845)2.36500837
66Abnormal protein glycosylation (HP:0012346)2.36165009
67Abnormal glycosylation (HP:0012345)2.36165009
68Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.36165009
69Abnormal protein N-linked glycosylation (HP:0012347)2.36165009
70Recurrent viral infections (HP:0004429)2.35802047
71Stomach cancer (HP:0012126)2.34143101
72Basal cell carcinoma (HP:0002671)2.32907886
73Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.31494154
74Nausea (HP:0002018)2.31219847
75Myelodysplasia (HP:0002863)2.30619267
76Breast hypoplasia (HP:0003187)2.29808697
77Pancreatic cysts (HP:0001737)2.27881693
78Hypoplasia of the pons (HP:0012110)2.27074478
79Sparse eyelashes (HP:0000653)2.26998193
80Premature graying of hair (HP:0002216)2.26862147
81Poor head control (HP:0002421)2.26772032
82Pancytopenia (HP:0001876)2.26730279
83Amaurosis fugax (HP:0100576)2.26550410
84Myositis (HP:0100614)2.26026103
85Leukocytosis (HP:0001974)2.24986010
86Chest pain (HP:0100749)2.22783860
8711 pairs of ribs (HP:0000878)2.22716204
88Alveolar cell carcinoma (HP:0006519)2.21138484
89Poikiloderma (HP:0001029)2.18446761
90Atrophy/Degeneration involving motor neurons (HP:0007373)2.17959604
91Recurrent bronchitis (HP:0002837)2.17805567
92Increased serum ferritin (HP:0003281)2.17384417
93Cellular immunodeficiency (HP:0005374)2.16601708
94Neoplasm of the tracheobronchial system (HP:0100552)2.16114116
95Autoimmune hemolytic anemia (HP:0001890)2.15653321
96IgG deficiency (HP:0004315)2.15221157
97Trismus (HP:0000211)2.11612016
98Urticaria (HP:0001025)2.10187883
99Lymphoma (HP:0002665)2.09871941
100Medulloblastoma (HP:0002885)2.08871457
101Inflammation of the large intestine (HP:0002037)2.08009852
102Recurrent sinusitis (HP:0011108)2.06903990
103Aplasia/Hypoplasia of the sacrum (HP:0008517)2.05636721
104Ependymoma (HP:0002888)2.05585721
105Parkinsonism with favorable response to dopaminergic medication (HP:0002548)2.05485470
106Absent thumb (HP:0009777)2.04547352
107Pulmonary fibrosis (HP:0002206)2.02345475
108Hypochromic microcytic anemia (HP:0004840)2.02337559
109Type II lissencephaly (HP:0007260)2.01484970
110Abnormality of eosinophils (HP:0001879)2.00457490
111Slender long bone (HP:0003100)1.98376207
112Abnormality of the prostate (HP:0008775)1.98251893
113Increased CSF lactate (HP:0002490)1.98247470
114Retinal dysplasia (HP:0007973)1.98218252
115Keratitis (HP:0000491)1.97318111
116Obstructive lung disease (HP:0006536)1.96943207
117Chronic obstructive pulmonary disease (HP:0006510)1.96943207
118Lactic acidosis (HP:0003128)1.95163614
119T lymphocytopenia (HP:0005403)1.94681392
120Muscle abnormality related to mitochondrial dysfunction (HP:0003800)1.94321816
121Entropion (HP:0000621)1.90774915
122Pustule (HP:0200039)1.90416012
123Neutropenia (HP:0001875)1.89760155
124Eosinophilia (HP:0001880)1.89727772
125Fatigue (HP:0012378)1.89406353
126Beaking of vertebral bodies (HP:0004568)1.88947168
127Abnormality of chromosome stability (HP:0003220)1.88422726
128Abnormal spermatogenesis (HP:0008669)1.87918369
129Neoplasm of the pancreas (HP:0002894)1.87031617
130Abnormality of cells of the lymphoid lineage (HP:0012140)1.86986583
131Rhabdomyosarcoma (HP:0002859)1.86768648
132Arterial thrombosis (HP:0004420)1.86140395
133Lymphopenia (HP:0001888)1.85484526
134Ragged-red muscle fibers (HP:0003200)1.85442825
135Increased hepatocellular lipid droplets (HP:0006565)1.85278794
136Angiofibromas (HP:0010615)1.85231311
137Adenoma sebaceum (HP:0009720)1.85231311
138Bone marrow hypocellularity (HP:0005528)1.84855065
139Abnormality of the pons (HP:0007361)1.84161859
140Anorexia (HP:0002039)1.83733716
1413-Methylglutaconic aciduria (HP:0003535)1.83190787
142Abnormality of glycolysis (HP:0004366)1.82635185
143Increased serum pyruvate (HP:0003542)1.82635185
144Progressive inability to walk (HP:0002505)1.82507124
145Increased IgE level (HP:0003212)1.82131565
146Granulocytopenia (HP:0001913)1.81620451
147Hypothermia (HP:0002045)1.81389675
148Increased intramyocellular lipid droplets (HP:0012240)1.80524009
149Pancreatic fibrosis (HP:0100732)1.80449530
150Mitochondrial inheritance (HP:0001427)1.80164975
151Cerebral hypomyelination (HP:0006808)1.79989210
152Abnormality of T cell number (HP:0011839)1.79752092
153Abnormality of the preputium (HP:0100587)1.79404926
154Verrucae (HP:0200043)1.79272096
155Papilloma (HP:0012740)1.79272096
156Gastrointestinal inflammation (HP:0004386)1.78674624
157Pulmonary infiltrates (HP:0002113)1.78518983
158Abnormality of reticulocytes (HP:0004312)1.78507374
159Respiratory difficulties (HP:0002880)1.77833760
160Recurrent gram-negative bacterial infections (HP:0005420)1.77037556
161Hypoplasia of the thymus (HP:0000778)1.76923530
162Abnormal biliary tract physiology (HP:0012439)1.76677672
163Bile duct proliferation (HP:0001408)1.76677672
164Abnormality of alanine metabolism (HP:0010916)1.75892937
165Hyperalaninemia (HP:0003348)1.75892937
166Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.75892937
167Hemoptysis (HP:0002105)1.75736804
168Episodic fever (HP:0001954)1.75506693
169Exertional dyspnea (HP:0002875)1.75379321
170Squamous cell carcinoma (HP:0002860)1.74779326
171Spontaneous hematomas (HP:0007420)1.74628121
172Chronic diarrhea (HP:0002028)1.74452028
173Amyotrophic lateral sclerosis (HP:0007354)1.74334510
174Gangrene (HP:0100758)1.74332951
175Constricted visual fields (HP:0001133)1.74125548
176Hematochezia (HP:0002573)1.73668587
177Gastrointestinal stroma tumor (HP:0100723)1.72539229

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TRIM284.37974651
2BUB13.69183200
3EIF2AK13.65521267
4WEE13.48293210
5NME23.47964562
6SIK33.31615504
7CDC73.26634682
8TESK22.52272135
9SCYL22.46882485
10EIF2AK32.27015440
11VRK12.25216539
12STK162.20772751
13RPS6KA42.20690943
14MAP4K12.18302981
15BRSK22.07087809
16NEK12.04935532
17EEF2K2.01935039
18MST42.01352010
19ACVR1B2.00766020
20BRD41.99073771
21RIPK41.99026163
22NEK21.87499445
23ZAK1.83136588
24MAP3K111.80248445
25PIM21.78945707
26BCR1.78341182
27FES1.75120187
28KDR1.74794778
29FLT31.61738809
30LRRK21.57482411
31FRK1.57310958
32RPS6KB21.53353758
33MAP2K31.53320126
34ZAP701.44328096
35PKN21.43195179
36SRPK11.42334670
37ERBB31.39808333
38BMPR21.36976312
39ITK1.34783988
40MAPKAPK31.34528088
41BRSK11.32626638
42PLK41.32139106
43TAOK31.29256200
44BCKDK1.28162215
45NUAK11.27929382
46PLK11.23701989
47TSSK61.21598914
48ATR1.19200932
49PAK41.17584538
50DYRK31.16250097
51CSK1.16026614
52TGFBR11.15515281
53MAP2K61.14203891
54CCNB11.12280309
55TAF11.10687449
56CDK71.09311188
57TESK11.09240805
58MAP3K121.09069619
59MAP4K21.08982017
60MAP3K81.08068981
61AURKB1.07468220
62KIT1.06975269
63TRIB31.06450492
64MAP2K71.02148804
65YES11.01858271
66TLK10.99746363
67BTK0.99352816
68TXK0.97609515
69STK100.97284593
70PASK0.96426138
71MAP3K140.95476110
72MAP3K40.94222905
73TYK20.91204754
74STK38L0.89542908
75MAP3K50.88997978
76MARK30.88509018
77IKBKB0.88306263
78AURKA0.87602118
79TTK0.87309028
80IRAK10.86625433
81JAK30.85625762
82WNK30.84914959
83KSR10.84811629
84IRAK40.84789409
85CDK190.83386749
86HCK0.83087940
87TEC0.82860975
88ILK0.81430788
89DAPK10.81372458
90MAP3K30.79847445
91IRAK20.79744540
92MAPK130.79427751
93MKNK20.79078511
94ERN10.76619294
95BLK0.74857479
96PIM10.74226608
97JAK20.74184529
98PRKCQ0.72049656
99TBK10.69900971
100CSF1R0.69154557
101DYRK1B0.67399364
102PLK30.67288870
103MKNK10.67188540
104CAMKK20.66598179
105PNCK0.65645242
106FGR0.64537701
107CDK40.64420454
108NME10.64346275
109MAP2K40.64280315
110PINK10.63237266
111EPHA20.62560509
112GRK10.62255641
113SYK0.61878926
114BRAF0.61783729
115CHEK20.61522210
116RAF10.57663283
117PIK3CG0.56668522
118STK40.55963828
119CHEK10.55848480
120MAP3K100.55631367
121PRKG20.55209127
122CSNK2A10.55145630
123IRAK30.55134963
124TAOK20.54977793
125CDK30.53486269
126PAK10.52178807
127CSNK2A20.51092961
128NLK0.50017721
129MAP3K60.48002470
130OXSR10.47090878
131MAPK70.43228119
132LYN0.43050184
133DYRK1A0.42466480
134CSNK1G10.42231822
135ARAF0.41422400
136AKT30.41320752
137CDK90.40737208
138GRK60.39746564
139TNK20.39742778
140JAK10.39704738
141EIF2AK20.39671339
142CSNK1G20.39552503
143MATK0.39301039
144MAP3K20.38473925
145CDK20.38211175
146MUSK0.37952374
147MYLK0.37916192
148STK240.37832339
149RPS6KA50.37681044
150LCK0.37468143
151ATM0.37151626
152IKBKE0.34482973
153CDK60.33083550
154TAOK10.31930504
155CHUK0.31866286
156ABL20.31579560
157MAPK110.30448844

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030304.85430393
2Ribosome_Homo sapiens_hsa030104.33204248
3Mismatch repair_Homo sapiens_hsa034303.98332602
4Proteasome_Homo sapiens_hsa030503.77413466
5Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.20746613
6RNA polymerase_Homo sapiens_hsa030203.14509780
7Base excision repair_Homo sapiens_hsa034103.03221166
8Spliceosome_Homo sapiens_hsa030402.91024663
9Graft-versus-host disease_Homo sapiens_hsa053322.86082090
10Autoimmune thyroid disease_Homo sapiens_hsa053202.79802160
11Pyrimidine metabolism_Homo sapiens_hsa002402.64507973
12Nucleotide excision repair_Homo sapiens_hsa034202.63857842
13Homologous recombination_Homo sapiens_hsa034402.54971456
14RNA transport_Homo sapiens_hsa030132.52137371
15Type I diabetes mellitus_Homo sapiens_hsa049402.42527896
16Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.41659997
17One carbon pool by folate_Homo sapiens_hsa006702.21791266
18Asthma_Homo sapiens_hsa053102.10819358
19Cell cycle_Homo sapiens_hsa041102.01448155
20RNA degradation_Homo sapiens_hsa030181.82942228
21Osteoclast differentiation_Homo sapiens_hsa043801.71028089
22Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.68233872
23Non-homologous end-joining_Homo sapiens_hsa034501.66529927
24Rheumatoid arthritis_Homo sapiens_hsa053231.55975808
25Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.54078412
26Fanconi anemia pathway_Homo sapiens_hsa034601.46170898
27p53 signaling pathway_Homo sapiens_hsa041151.44060430
28Antigen processing and presentation_Homo sapiens_hsa046121.38508648
29Regulation of autophagy_Homo sapiens_hsa041401.35362920
30Protein export_Homo sapiens_hsa030601.35038230
31Primary immunodeficiency_Homo sapiens_hsa053401.33256897
32Staphylococcus aureus infection_Homo sapiens_hsa051501.31834486
33Sulfur relay system_Homo sapiens_hsa041221.30394199
34Basal transcription factors_Homo sapiens_hsa030221.29826274
35Purine metabolism_Homo sapiens_hsa002301.29663509
36Pentose phosphate pathway_Homo sapiens_hsa000301.27604623
37Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.26493074
38Epstein-Barr virus infection_Homo sapiens_hsa051691.21929104
39Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.16046473
40Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.14328933
41Folate biosynthesis_Homo sapiens_hsa007901.12794998
42Cysteine and methionine metabolism_Homo sapiens_hsa002701.10967563
43Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.04630108
44N-Glycan biosynthesis_Homo sapiens_hsa005101.01144608
45Herpes simplex infection_Homo sapiens_hsa051681.00750693
46Biosynthesis of amino acids_Homo sapiens_hsa012300.98862131
47Chemokine signaling pathway_Homo sapiens_hsa040620.98833046
48TNF signaling pathway_Homo sapiens_hsa046680.96967026
49Selenocompound metabolism_Homo sapiens_hsa004500.95843922
50mRNA surveillance pathway_Homo sapiens_hsa030150.95106448
51Drug metabolism - other enzymes_Homo sapiens_hsa009830.87176336
52Thyroid cancer_Homo sapiens_hsa052160.83348294
53Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.80745080
54Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.79845255
55Legionellosis_Homo sapiens_hsa051340.76984554
56Viral carcinogenesis_Homo sapiens_hsa052030.76431572
57Parkinsons disease_Homo sapiens_hsa050120.75968129
58Measles_Homo sapiens_hsa051620.75252773
59Systemic lupus erythematosus_Homo sapiens_hsa053220.74543838
60RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.74055276
61Shigellosis_Homo sapiens_hsa051310.73307689
62Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.70125642
63Apoptosis_Homo sapiens_hsa042100.68235988
64HTLV-I infection_Homo sapiens_hsa051660.67069664
65Collecting duct acid secretion_Homo sapiens_hsa049660.66592006
66Cyanoamino acid metabolism_Homo sapiens_hsa004600.65152711
67Huntingtons disease_Homo sapiens_hsa050160.64534805
68Carbon metabolism_Homo sapiens_hsa012000.64254879
69Fructose and mannose metabolism_Homo sapiens_hsa000510.64028175
702-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.63913981
71Galactose metabolism_Homo sapiens_hsa000520.63659310
72Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.62985673
73Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.62936587
74African trypanosomiasis_Homo sapiens_hsa051430.61461844
75Salmonella infection_Homo sapiens_hsa051320.61353844
76Phagosome_Homo sapiens_hsa041450.61181945
77Hematopoietic cell lineage_Homo sapiens_hsa046400.61054854
78Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.60007730
79Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.58753135
80Leishmaniasis_Homo sapiens_hsa051400.58379131
81Dorso-ventral axis formation_Homo sapiens_hsa043200.54683028
82Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.53751463
83Malaria_Homo sapiens_hsa051440.53354229
84Oocyte meiosis_Homo sapiens_hsa041140.53077020
85Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.51452884
86Acute myeloid leukemia_Homo sapiens_hsa052210.49514033
87Hepatitis C_Homo sapiens_hsa051600.49191050
88NF-kappa B signaling pathway_Homo sapiens_hsa040640.49177039
89Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.46982017
90Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.46583863
91Non-small cell lung cancer_Homo sapiens_hsa052230.45118959
92Circadian rhythm_Homo sapiens_hsa047100.44248288
93Hepatitis B_Homo sapiens_hsa051610.43389760
94Influenza A_Homo sapiens_hsa051640.42893676
95Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.41613967
96Glutathione metabolism_Homo sapiens_hsa004800.41246349
97Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.39114965
98B cell receptor signaling pathway_Homo sapiens_hsa046620.38457225
99Prolactin signaling pathway_Homo sapiens_hsa049170.38167588
100Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.37674334
101Other glycan degradation_Homo sapiens_hsa005110.37038175
102Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.36362450
103Alcoholism_Homo sapiens_hsa050340.35282882
104T cell receptor signaling pathway_Homo sapiens_hsa046600.35262483
105FoxO signaling pathway_Homo sapiens_hsa040680.34351770
106Transcriptional misregulation in cancer_Homo sapiens_hsa052020.33245728
107Phototransduction_Homo sapiens_hsa047440.32946031
108Sphingolipid signaling pathway_Homo sapiens_hsa040710.30795654
109Oxidative phosphorylation_Homo sapiens_hsa001900.30661801
110Jak-STAT signaling pathway_Homo sapiens_hsa046300.30174898
111Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.30136524
112Pancreatic cancer_Homo sapiens_hsa052120.29685824
113NOD-like receptor signaling pathway_Homo sapiens_hsa046210.29057362
114Bladder cancer_Homo sapiens_hsa052190.28530286
115Small cell lung cancer_Homo sapiens_hsa052220.27581489
116Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.26889177
117Inositol phosphate metabolism_Homo sapiens_hsa005620.26712149
118Central carbon metabolism in cancer_Homo sapiens_hsa052300.26612188
119HIF-1 signaling pathway_Homo sapiens_hsa040660.26464201
120Intestinal immune network for IgA production_Homo sapiens_hsa046720.25693457
121Colorectal cancer_Homo sapiens_hsa052100.25339474
122Viral myocarditis_Homo sapiens_hsa054160.25032665
123Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.24551524
124Allograft rejection_Homo sapiens_hsa053300.24469172
125Metabolic pathways_Homo sapiens_hsa011000.23726056
126Renin-angiotensin system_Homo sapiens_hsa046140.20857139
127Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.20107652
128Toxoplasmosis_Homo sapiens_hsa051450.19015202
129Toll-like receptor signaling pathway_Homo sapiens_hsa046200.17987449
130SNARE interactions in vesicular transport_Homo sapiens_hsa041300.17355301
131Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.16781098
132Pertussis_Homo sapiens_hsa051330.16735086
133Tuberculosis_Homo sapiens_hsa051520.16071680
134Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.15234638

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