

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | regulation of T-helper 2 cell differentiation (GO:0045628) | 9.90237373 |
| 2 | negative regulation of type 2 immune response (GO:0002829) | 9.86415585 |
| 3 | positive regulation of RNA splicing (GO:0033120) | 9.77330963 |
| 4 | activation of protein kinase A activity (GO:0034199) | 9.56583397 |
| 5 | negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515) | 9.39235413 |
| 6 | seminiferous tubule development (GO:0072520) | 9.35663321 |
| 7 | negative regulation of alpha-beta T cell differentiation (GO:0046639) | 8.58898751 |
| 8 | detection of chemical stimulus involved in sensory perception (GO:0050907) | 8.42063926 |
| 9 | cAMP biosynthetic process (GO:0006171) | 8.33454599 |
| 10 | enteric nervous system development (GO:0048484) | 7.46822645 |
| 11 | regulation of protein sumoylation (GO:0033233) | 7.30814102 |
| 12 | positive regulation of mitochondrial fission (GO:0090141) | 7.21022385 |
| 13 | synaptic transmission, dopaminergic (GO:0001963) | 7.05605437 |
| 14 | righting reflex (GO:0060013) | 6.89194689 |
| 15 | dendritic spine morphogenesis (GO:0060997) | 6.83114975 |
| 16 | positive regulation of T-helper 1 type immune response (GO:0002827) | 6.47342216 |
| 17 | heterotypic cell-cell adhesion (GO:0034113) | 6.12432976 |
| 18 | hepatocyte apoptotic process (GO:0097284) | 6.10452067 |
| 19 | detection of chemical stimulus (GO:0009593) | 5.97997744 |
| 20 | icosanoid secretion (GO:0032309) | 5.82644837 |
| 21 | arachidonic acid secretion (GO:0050482) | 5.82644837 |
| 22 | endothelial cell differentiation (GO:0045446) | 5.66178813 |
| 23 | positive regulation of T-helper cell differentiation (GO:0045624) | 5.62352313 |
| 24 | phosphatidylinositol acyl-chain remodeling (GO:0036149) | 5.25357932 |
| 25 | regulation of mitochondrial fission (GO:0090140) | 5.21424436 |
| 26 | drug transmembrane transport (GO:0006855) | 5.20150132 |
| 27 | phosphatidylserine acyl-chain remodeling (GO:0036150) | 4.91114265 |
| 28 | negative regulation of alpha-beta T cell activation (GO:0046636) | 4.84973545 |
| 29 | neural tube formation (GO:0001841) | 4.79694121 |
| 30 | fatty acid derivative transport (GO:1901571) | 4.77727539 |
| 31 | icosanoid transport (GO:0071715) | 4.77727539 |
| 32 | regulation of T-helper 1 type immune response (GO:0002825) | 4.68984558 |
| 33 | phosphatidylglycerol acyl-chain remodeling (GO:0036148) | 4.66983525 |
| 34 | attachment of spindle microtubules to kinetochore (GO:0008608) | 4.59511794 |
| 35 | chemosensory behavior (GO:0007635) | 4.59072658 |
| 36 | neuronal ion channel clustering (GO:0045161) | 4.50099029 |
| 37 | ATP hydrolysis coupled proton transport (GO:0015991) | 4.46119347 |
| 38 | energy coupled proton transmembrane transport, against electrochemical gradient (GO:0015988) | 4.46119347 |
| 39 | embryonic digestive tract morphogenesis (GO:0048557) | 4.43183012 |
| 40 | regulation of T-helper cell differentiation (GO:0045622) | 4.40599485 |
| 41 | nephron epithelium morphogenesis (GO:0072088) | 4.29477646 |
| 42 | nephron tubule morphogenesis (GO:0072078) | 4.29477646 |
| 43 | positive regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043372) | 4.25247277 |
| 44 | cyclic purine nucleotide metabolic process (GO:0052652) | 4.23001944 |
| 45 | hyaluronan catabolic process (GO:0030214) | 4.22647752 |
| 46 | cyclic nucleotide biosynthetic process (GO:0009190) | 4.18090846 |
| 47 | cilium or flagellum-dependent cell motility (GO:0001539) | 4.17264638 |
| 48 | vocalization behavior (GO:0071625) | 4.11299403 |
| 49 | regulation of cAMP-mediated signaling (GO:0043949) | 4.10221900 |
| 50 | mitochondrial fusion (GO:0008053) | 4.05308572 |
| 51 | response to dietary excess (GO:0002021) | 4.05253287 |
| 52 | positive regulation of membrane potential (GO:0045838) | 4.03850590 |
| 53 | dendritic spine organization (GO:0097061) | 3.98500692 |
| 54 | cellular response to glucagon stimulus (GO:0071377) | 3.93581228 |
| 55 | cAMP metabolic process (GO:0046058) | 3.90490167 |
| 56 | protein localization to synapse (GO:0035418) | 3.90240075 |
| 57 | retina layer formation (GO:0010842) | 3.90208552 |
| 58 | negative regulation of actin filament bundle assembly (GO:0032232) | 3.89978616 |
| 59 | regulation of type 2 immune response (GO:0002828) | 3.84028371 |
| 60 | leukotriene biosynthetic process (GO:0019370) | 3.83920069 |
| 61 | negative regulation of T cell differentiation (GO:0045581) | 3.80754401 |
| 62 | water transport (GO:0006833) | 3.80346894 |
| 63 | positive regulation of CD4-positive, alpha-beta T cell activation (GO:2000516) | 3.73139365 |
| 64 | reflex (GO:0060004) | 3.63320685 |
| 65 | cellular zinc ion homeostasis (GO:0006882) | 3.58861409 |
| 66 | monoamine transport (GO:0015844) | 3.55880068 |
| 67 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.53584358 |
| 68 | drug transport (GO:0015893) | 3.52250068 |
| 69 | positive regulation of alpha-beta T cell differentiation (GO:0046638) | 3.49644924 |
| 70 | negative regulation of cytosolic calcium ion concentration (GO:0051481) | 3.47556181 |
| 71 | regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043370) | 3.45056916 |
| 72 | positive regulation of protein targeting to membrane (GO:0090314) | 3.43741704 |
| 73 | positive regulation of steroid hormone secretion (GO:2000833) | 3.42906059 |
| 74 | phosphatidylethanolamine acyl-chain remodeling (GO:0036152) | 3.41094846 |
| 75 | fluid transport (GO:0042044) | 3.38450607 |
| 76 | cytoskeletal anchoring at plasma membrane (GO:0007016) | 3.31124839 |
| 77 | positive regulation of extrinsic apoptotic signaling pathway via death domain receptors (GO:1902043) | 3.30294314 |
| 78 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.25788634 |
| 79 | cellular response to ATP (GO:0071318) | 3.24952265 |
| 80 | pre-miRNA processing (GO:0031054) | 3.24594263 |
| 81 | renal tubule morphogenesis (GO:0061333) | 3.22017213 |
| 82 | sequestering of metal ion (GO:0051238) | 3.21579481 |
| 83 | negative regulation of astrocyte differentiation (GO:0048712) | 3.16501793 |
| 84 | sulfur amino acid catabolic process (GO:0000098) | 3.13051844 |
| 85 | left/right axis specification (GO:0070986) | 3.12566788 |
| 86 | prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis (GO:006052 | 3.10443483 |
| 87 | regulation of alpha-beta T cell differentiation (GO:0046637) | 3.08785075 |
| 88 | negative regulation of homotypic cell-cell adhesion (GO:0034111) | 3.02963360 |
| 89 | adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway (GO:0007193) | 3.02623585 |
| 90 | adenylate cyclase-activating G-protein coupled receptor signaling pathway (GO:0007189) | 3.02129029 |
| 91 | regulation of CD4-positive, alpha-beta T cell activation (GO:2000514) | 2.99890952 |
| 92 | response to glucagon (GO:0033762) | 2.99740725 |
| 93 | regulation of relaxation of muscle (GO:1901077) | 2.98938784 |
| 94 | detection of chemical stimulus involved in sensory perception of smell (GO:0050911) | 13.3922424 |
| 95 | tooth mineralization (GO:0034505) | 13.3600208 |
| 96 | negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371) | 11.7030797 |
| 97 | negative regulation of T-helper cell differentiation (GO:0045623) | 11.7030797 |
| 98 | positive regulation of protein sumoylation (GO:0033235) | 11.4505308 |
| 99 | protein K11-linked deubiquitination (GO:0035871) | 10.4609447 |
| 100 | regulation of T-helper 1 cell differentiation (GO:0045625) | 10.2954864 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 6.57179193 |
| 2 | VDR_22108803_ChIP-Seq_LS180_Human | 5.43777441 |
| 3 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 5.16788148 |
| 4 | IGF1R_20145208_ChIP-Seq_DFB_Human | 5.03168038 |
| 5 | AR_21572438_ChIP-Seq_LNCaP_Human | 4.96697146 |
| 6 | PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse | 3.00962848 |
| 7 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 2.06162290 |
| 8 | TP53_16413492_ChIP-PET_HCT116_Human | 2.02550567 |
| 9 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 2.01980395 |
| 10 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 11.4141313 |
| 11 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.99853962 |
| 12 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.99853962 |
| 13 | YY1_22570637_ChIP-Seq_MALME-3M_Human | 1.98301744 |
| 14 | NR3C1_23031785_ChIP-Seq_PC12_Mouse | 1.78185052 |
| 15 | ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 1.71569860 |
| 16 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.70130610 |
| 17 | GATA1_19941826_ChIP-Seq_K562_Human | 1.69809708 |
| 18 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 1.66739283 |
| 19 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.63342082 |
| 20 | EGR1_19032775_ChIP-ChIP_M12_Human | 1.52143240 |
| 21 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.51768415 |
| 22 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 1.44660544 |
| 23 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 1.44590463 |
| 24 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.43429499 |
| 25 | DROSHA_22980978_ChIP-Seq_HELA_Human | 1.42541313 |
| 26 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.36696132 |
| 27 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.33430861 |
| 28 | SMAD3_21741376_ChIP-Seq_HESCs_Human | 1.32577639 |
| 29 | RXR_22108803_ChIP-Seq_LS180_Human | 1.32072427 |
| 30 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.32016091 |
| 31 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 1.30187568 |
| 32 | TCF12/HEB_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.28665933 |
| 33 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.28346408 |
| 34 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.24032434 |
| 35 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 1.23341569 |
| 36 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 1.21691950 |
| 37 | EZH2_22144423_ChIP-Seq_EOC_Human | 1.15105834 |
| 38 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 1.15030878 |
| 39 | KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse | 1.14199349 |
| 40 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 1.14113966 |
| 41 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.12844571 |
| 42 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 1.11431364 |
| 43 | CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse | 1.11113680 |
| 44 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 1.10303073 |
| 45 | HIF1A_21447827_ChIP-Seq_MCF-7_Human | 1.09740882 |
| 46 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.08575901 |
| 47 | SOX2_18555785_Chip-Seq_ESCs_Mouse | 1.07495358 |
| 48 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 1.04695165 |
| 49 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 1.04466761 |
| 50 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 1.04443985 |
| 51 | GATA6_21074721_ChIP-Seq_CACO-2_Human | 1.03895212 |
| 52 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.03698439 |
| 53 | HNFA_21074721_ChIP-Seq_CACO-2_Human | 1.01981338 |
| 54 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.01539771 |
| 55 | CMYC_18555785_Chip-Seq_ESCs_Mouse | 0.99536126 |
| 56 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 0.98543526 |
| 57 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.98399036 |
| 58 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 0.97706723 |
| 59 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 0.97454061 |
| 60 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 0.96686807 |
| 61 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 0.95735306 |
| 62 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 0.94908858 |
| 63 | TBL1_22424771_ChIP-Seq_293T_Human | 0.94297631 |
| 64 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.94144719 |
| 65 | SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 0.93884126 |
| 66 | PHF8_20622853_ChIP-Seq_HELA_Human | 0.93874205 |
| 67 | STAT3_23295773_ChIP-Seq_U87_Human | 0.91712221 |
| 68 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 0.91111719 |
| 69 | CBP_20019798_ChIP-Seq_JUKART_Human | 0.91111719 |
| 70 | TRIM28_17542650_ChIP-ChIP_NTERA2_Human | 0.91042705 |
| 71 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 0.90841837 |
| 72 | SUZ12_18555785_Chip-Seq_ESCs_Mouse | 0.90710683 |
| 73 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 0.90527428 |
| 74 | NR1I2_20693526_ChIP-Seq_LIVER_Mouse | 0.90398957 |
| 75 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 0.90095290 |
| 76 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 0.89756035 |
| 77 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 0.89492777 |
| 78 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 0.87822809 |
| 79 | CDX2_21074721_ChIP-Seq_CACO-2_Mouse | 0.87273982 |
| 80 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 0.87068824 |
| 81 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 0.86918150 |
| 82 | BCAT_22108803_ChIP-Seq_LS180_Human | 0.86735631 |
| 83 | SMAD4_21799915_ChIP-Seq_A2780_Human | 0.86524912 |
| 84 | KLF4_18555785_Chip-Seq_ESCs_Mouse | 0.85729841 |
| 85 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 0.85034306 |
| 86 | CJUN_26792858_Chip-Seq_BT549_Human | 0.84851011 |
| 87 | NMYC_18555785_Chip-Seq_ESCs_Mouse | 0.84661686 |
| 88 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 0.83802248 |
| 89 | DNAJC2_21179169_ChIP-ChIP_NT2_Human | 0.83728504 |
| 90 | SMAD4_21741376_ChIP-Seq_HESCs_Human | 0.82171374 |
| 91 | E2F1_18555785_Chip-Seq_ESCs_Mouse | 0.81812735 |
| 92 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 0.81808822 |
| 93 | PCGF4_22325352_ChIP-Seq_293T-Rex_Human | 0.81686964 |
| 94 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 0.80420485 |
| 95 | P53_22387025_ChIP-Seq_ESCs_Mouse | 0.79772908 |
| 96 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 0.79698742 |
| 97 | BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 0.79157229 |
| 98 | GATA6_21074721_ChIP-Seq_CACO-2_Mouse | 0.77725196 |
| 99 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 0.77673272 |
| 100 | NANOG_20526341_ChIP-Seq_ESCs_Human | 0.77301839 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0008961_abnormal_basal_metabolism | 9.34065718 |
| 2 | MP0004130_abnormal_muscle_cell | 4.65349532 |
| 3 | MP0004264_abnormal_extraembryonic_tissu | 3.54941838 |
| 4 | MP0003252_abnormal_bile_duct | 3.44419784 |
| 5 | MP0004133_heterotaxia | 2.61923656 |
| 6 | MP0006072_abnormal_retinal_apoptosis | 2.56277794 |
| 7 | MP0002928_abnormal_bile_duct | 2.45253397 |
| 8 | MP0002751_abnormal_autonomic_nervous | 2.28217662 |
| 9 | MP0005408_hypopigmentation | 2.21370302 |
| 10 | MP0005448_abnormal_energy_balance | 2.13405181 |
| 11 | MP0005084_abnormal_gallbladder_morpholo | 12.4186997 |
| 12 | MP0001270_distended_abdomen | 1.88314094 |
| 13 | MP0005379_endocrine/exocrine_gland_phen | 1.69359983 |
| 14 | MP0001529_abnormal_vocalization | 1.64068349 |
| 15 | MP0004272_abnormal_basement_membrane | 1.60988307 |
| 16 | MP0003329_amyloid_beta_deposits | 1.60666521 |
| 17 | MP0003943_abnormal_hepatobiliary_system | 1.57518179 |
| 18 | MP0005165_increased_susceptibility_to | 1.51088151 |
| 19 | MP0005220_abnormal_exocrine_pancreas | 1.45423988 |
| 20 | MP0009764_decreased_sensitivity_to | 1.33151405 |
| 21 | MP0008875_abnormal_xenobiotic_pharmacok | 1.18018385 |
| 22 | MP0005646_abnormal_pituitary_gland | 1.16194435 |
| 23 | MP0001905_abnormal_dopamine_level | 1.15640277 |
| 24 | MP0003718_maternal_effect | 1.13571994 |
| 25 | MP0000604_amyloidosis | 1.07087557 |
| 26 | MP0003195_calcinosis | 1.04568451 |
| 27 | MP0000372_irregular_coat_pigmentation | 1.02360402 |
| 28 | MP0000470_abnormal_stomach_morphology | 1.01970888 |
| 29 | MP0001958_emphysema | 0.98786905 |
| 30 | MP0008569_lethality_at_weaning | 0.98573155 |
| 31 | MP0002572_abnormal_emotion/affect_behav | 0.97386855 |
| 32 | MP0002405_respiratory_system_inflammati | 0.96845534 |
| 33 | MP0005387_immune_system_phenotype | 0.93068057 |
| 34 | MP0001790_abnormal_immune_system | 0.93068057 |
| 35 | MP0000465_gastrointestinal_hemorrhage | 0.91560478 |
| 36 | MP0003866_abnormal_defecation | 0.89742420 |
| 37 | MP0003638_abnormal_response/metabolism_ | 0.86254062 |
| 38 | MP0002909_abnormal_adrenal_gland | 0.83723272 |
| 39 | MP0001800_abnormal_humoral_immune | 0.83406011 |
| 40 | MP0005253_abnormal_eye_physiology | 0.81848486 |
| 41 | MP0001944_abnormal_pancreas_morphology | 0.80726619 |
| 42 | MP0004019_abnormal_vitamin_homeostasis | 0.79552491 |
| 43 | MP0000703_abnormal_thymus_morphology | 0.79356348 |
| 44 | MP0008469_abnormal_protein_level | 0.77196219 |
| 45 | MP0004145_abnormal_muscle_electrophysio | 0.75740937 |
| 46 | MP0002254_reproductive_system_inflammat | 0.75304288 |
| 47 | MP0000759_abnormal_skeletal_muscle | 0.74348737 |
| 48 | MP0004947_skin_inflammation | 0.71254313 |
| 49 | MP0000609_abnormal_liver_physiology | 0.71060109 |
| 50 | MP0002822_catalepsy | 0.67795705 |
| 51 | MP0004381_abnormal_hair_follicle | 0.67358991 |
| 52 | MP0002736_abnormal_nociception_after | 0.66092835 |
| 53 | MP0001835_abnormal_antigen_presentation | 0.65697172 |
| 54 | MP0001533_abnormal_skeleton_physiology | 0.64597270 |
| 55 | MP0000371_diluted_coat_color | 0.64080444 |
| 56 | MP0002098_abnormal_vibrissa_morphology | 0.61770415 |
| 57 | MP0003121_genomic_imprinting | 0.61327191 |
| 58 | MP0001915_intracranial_hemorrhage | 0.60889569 |
| 59 | MP0002136_abnormal_kidney_physiology | 0.60067994 |
| 60 | MP0004484_altered_response_of | 0.58932981 |
| 61 | MP0002138_abnormal_hepatobiliary_system | 0.56546495 |
| 62 | MP0002722_abnormal_immune_system | 0.55393835 |
| 63 | MP0002693_abnormal_pancreas_physiology | 0.54083649 |
| 64 | MP0003953_abnormal_hormone_level | 0.52600856 |
| 65 | MP0001502_abnormal_circadian_rhythm | 0.51168026 |
| 66 | MP0009785_altered_susceptibility_to | 0.51082351 |
| 67 | MP0003763_abnormal_thymus_physiology | 0.50196982 |
| 68 | MP0005671_abnormal_response_to | 0.49524890 |
| 69 | MP0002078_abnormal_glucose_homeostasis | 0.48976132 |
| 70 | MP0001542_abnormal_bone_strength | 0.48967692 |
| 71 | MP0001845_abnormal_inflammatory_respons | 0.48820867 |
| 72 | MP0004036_abnormal_muscle_relaxation | 0.48744487 |
| 73 | MP0005551_abnormal_eye_electrophysiolog | 0.48123305 |
| 74 | MP0003646_muscle_fatigue | 0.47969262 |
| 75 | MP0005645_abnormal_hypothalamus_physiol | 0.46888682 |
| 76 | MP0003436_decreased_susceptibility_to | 0.46649399 |
| 77 | MP0002106_abnormal_muscle_physiology | 0.44755789 |
| 78 | MP0001501_abnormal_sleep_pattern | 0.43675125 |
| 79 | MP0001968_abnormal_touch/_nociception | 0.43606202 |
| 80 | MP0005360_urolithiasis | 0.42570808 |
| 81 | MP0002723_abnormal_immune_serum | 0.41725286 |
| 82 | MP0002638_abnormal_pupillary_reflex | 0.41359516 |
| 83 | MP0002452_abnormal_antigen_presenting | 0.41151091 |
| 84 | MP0001819_abnormal_immune_cell | 0.40412778 |
| 85 | MP0002420_abnormal_adaptive_immunity | 0.40168913 |
| 86 | MP0002229_neurodegeneration | 0.39300555 |
| 87 | MP0006276_abnormal_autonomic_nervous | 0.39107650 |
| 88 | MP0001851_eye_inflammation | 0.39053083 |
| 89 | MP0005164_abnormal_response_to | 0.38526045 |
| 90 | MP0004147_increased_porphyrin_level | 0.36866023 |
| 91 | MP0009642_abnormal_blood_homeostasis | 0.36727841 |
| 92 | MP0002429_abnormal_blood_cell | 0.36713263 |
| 93 | MP0003136_yellow_coat_color | 0.36623445 |
| 94 | MP0005000_abnormal_immune_tolerance | 0.36565768 |
| 95 | MP0005620_abnormal_muscle_contractility | 0.36148206 |
| 96 | MP0002998_abnormal_bone_remodeling | 0.35715697 |
| 97 | MP0000716_abnormal_immune_system | 0.35150736 |
| 98 | MP0005167_abnormal_blood-brain_barrier | 0.34805574 |
| 99 | MP0005334_abnormal_fat_pad | 0.34315744 |
| 100 | MP0000477_abnormal_intestine_morphology | 0.33092134 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Abnormality of calcium-phosphate metabolism (HP:0100530) | 9.50145790 |
| 2 | Abnormality of dental color (HP:0011073) | 7.70683271 |
| 3 | Abnormality of renal resorption (HP:0011038) | 7.63019501 |
| 4 | Polyuria (HP:0000103) | 7.26034886 |
| 5 | Osteomalacia (HP:0002749) | 6.81374984 |
| 6 | Abnormality of the dental pulp (HP:0006479) | 6.77627024 |
| 7 | Round ear (HP:0100830) | 6.58764130 |
| 8 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 6.27776373 |
| 9 | Abnormal urine output (HP:0012590) | 6.19326491 |
| 10 | Autoimmune thrombocytopenia (HP:0001973) | 5.70331620 |
| 11 | Abnormality of renal excretion (HP:0011036) | 5.33039008 |
| 12 | Chronic bronchitis (HP:0004469) | 4.62657302 |
| 13 | Volvulus (HP:0002580) | 4.33527155 |
| 14 | Toxemia of pregnancy (HP:0100603) | 4.24960024 |
| 15 | IgM deficiency (HP:0002850) | 4.04081328 |
| 16 | Lip pit (HP:0100267) | 4.00710784 |
| 17 | Molar tooth sign on MRI (HP:0002419) | 3.87605830 |
| 18 | Abnormality of midbrain morphology (HP:0002418) | 3.87605830 |
| 19 | Lipoatrophy (HP:0100578) | 3.42667635 |
| 20 | Nephrocalcinosis (HP:0000121) | 3.40873091 |
| 21 | Depressed nasal tip (HP:0000437) | 3.33725904 |
| 22 | Rhinitis (HP:0012384) | 3.23778163 |
| 23 | Esophageal varix (HP:0002040) | 3.15469115 |
| 24 | Abnormal respiratory motile cilium physiology (HP:0012261) | 3.04620816 |
| 25 | Tachypnea (HP:0002789) | 3.02484462 |
| 26 | Drooling (HP:0002307) | 3.01330351 |
| 27 | Hyperphosphaturia (HP:0003109) | 2.95696424 |
| 28 | Large earlobe (HP:0009748) | 2.93997405 |
| 29 | Excessive salivation (HP:0003781) | 2.85739861 |
| 30 | Hypoparathyroidism (HP:0000829) | 2.85453822 |
| 31 | Abnormality of the fingertips (HP:0001211) | 2.78705606 |
| 32 | Sparse lateral eyebrow (HP:0005338) | 2.77645512 |
| 33 | Nephronophthisis (HP:0000090) | 2.69865762 |
| 34 | Inability to walk (HP:0002540) | 2.65048797 |
| 35 | Panhypogammaglobulinemia (HP:0003139) | 2.63480526 |
| 36 | Autoimmune hemolytic anemia (HP:0001890) | 2.56531483 |
| 37 | Thick eyebrow (HP:0000574) | 2.53783518 |
| 38 | Mask-like facies (HP:0000298) | 2.53509018 |
| 39 | Glycosuria (HP:0003076) | 2.43116325 |
| 40 | Abnormality of urine glucose concentration (HP:0011016) | 2.43116325 |
| 41 | Dilated cardiomyopathy (HP:0001644) | 2.42333672 |
| 42 | Abnormal urine phosphate concentration (HP:0012599) | 2.40934404 |
| 43 | Intestinal fistula (HP:0100819) | 2.40063832 |
| 44 | Recurrent cutaneous fungal infections (HP:0011370) | 2.38839456 |
| 45 | Chronic mucocutaneous candidiasis (HP:0002728) | 2.38839456 |
| 46 | Ureteral stenosis (HP:0000071) | 2.26315049 |
| 47 | Abnormality of transition element cation homeostasis (HP:0011030) | 2.25757600 |
| 48 | Hepatitis (HP:0012115) | 2.12123565 |
| 49 | Personality changes (HP:0000751) | 2.11448488 |
| 50 | Decreased muscle mass (HP:0003199) | 2.10955788 |
| 51 | Nephropathy (HP:0000112) | 2.10513038 |
| 52 | Ureteral obstruction (HP:0006000) | 2.08640983 |
| 53 | Bronchitis (HP:0012387) | 2.08398110 |
| 54 | Striae distensae (HP:0001065) | 2.06051254 |
| 55 | Overgrowth (HP:0001548) | 11.0486842 |
| 56 | Amelogenesis imperfecta (HP:0000705) | 10.7980783 |
| 57 | Hypercalciuria (HP:0002150) | 1.94766724 |
| 58 | Abnormality of salivation (HP:0100755) | 1.93373230 |
| 59 | Gingival overgrowth (HP:0000212) | 1.91766653 |
| 60 | Abnormality of the renal medulla (HP:0100957) | 1.91156104 |
| 61 | Anal stenosis (HP:0002025) | 1.90514890 |
| 62 | Distal arthrogryposis (HP:0005684) | 1.89005074 |
| 63 | Petechiae (HP:0000967) | 1.86020305 |
| 64 | Sudden cardiac death (HP:0001645) | 1.85332969 |
| 65 | Short 5th finger (HP:0009237) | 1.84863417 |
| 66 | Nemaline bodies (HP:0003798) | 1.84529424 |
| 67 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 1.84010989 |
| 68 | Small hand (HP:0200055) | 1.82508253 |
| 69 | Delayed eruption of teeth (HP:0000684) | 1.81851080 |
| 70 | Periauricular skin pits (HP:0100277) | 1.81424080 |
| 71 | Preauricular pit (HP:0004467) | 1.81424080 |
| 72 | Chorioretinal coloboma (HP:0000567) | 1.80165345 |
| 73 | Recurrent otitis media (HP:0000403) | 1.80044182 |
| 74 | Prominent supraorbital ridges (HP:0000336) | 1.79485179 |
| 75 | Aplasia/Hypoplasia of the 5th finger (HP:0006262) | 1.78633540 |
| 76 | Visual hallucinations (HP:0002367) | 1.78121612 |
| 77 | Chondrocalcinosis (HP:0000934) | 1.76885034 |
| 78 | Muscle fiber inclusion bodies (HP:0100299) | 1.75140348 |
| 79 | Elevated erythrocyte sedimentation rate (HP:0003565) | 1.74591697 |
| 80 | Renal tubular dysfunction (HP:0000124) | 1.73845804 |
| 81 | Abnormality of Sharpey fibers (HP:0100685) | 1.73613737 |
| 82 | Preauricular skin tag (HP:0000384) | 1.71686335 |
| 83 | Muscle fiber cytoplasmatic inclusion bodies (HP:0100303) | 1.67339865 |
| 84 | Ectopic kidney (HP:0000086) | 1.63535532 |
| 85 | Polyneuropathy (HP:0001271) | 1.59547146 |
| 86 | Absent phalangeal crease (HP:0006109) | 1.59263562 |
| 87 | Congenital stationary night blindness (HP:0007642) | 1.58094737 |
| 88 | Testicular atrophy (HP:0000029) | 1.57257260 |
| 89 | Abnormality of the fovea (HP:0000493) | 1.55415610 |
| 90 | Abnormality of T cell physiology (HP:0011840) | 1.54111346 |
| 91 | Palpebral edema (HP:0100540) | 1.51244368 |
| 92 | Palmoplantar keratoderma (HP:0000982) | 1.50768272 |
| 93 | Bronchiectasis (HP:0002110) | 1.50167653 |
| 94 | Skin tags (HP:0010609) | 1.48435470 |
| 95 | Delayed gross motor development (HP:0002194) | 1.47337870 |
| 96 | Calcaneovalgus deformity (HP:0001848) | 1.46904329 |
| 97 | Stage 5 chronic kidney disease (HP:0003774) | 1.44785937 |
| 98 | Blepharitis (HP:0000498) | 1.44740804 |
| 99 | Abnormality of purine metabolism (HP:0004352) | 1.42564272 |
| 100 | Limited elbow extension (HP:0001377) | 1.42195716 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MAP4K1 | 5.68239869 |
| 2 | BLK | 3.78490539 |
| 3 | STK3 | 3.69258008 |
| 4 | RIPK4 | 2.43163892 |
| 5 | BMPR2 | 2.30412597 |
| 6 | NEK1 | 2.06706929 |
| 7 | NTRK2 | 13.3965636 |
| 8 | CDC42BPA | 1.70885600 |
| 9 | MUSK | 1.64958734 |
| 10 | OBSCN | 1.19006676 |
| 11 | TXK | 1.18094842 |
| 12 | WNK4 | 1.09570130 |
| 13 | HIPK2 | 1.05380720 |
| 14 | TIE1 | 1.04547670 |
| 15 | PHKG2 | 1.03622777 |
| 16 | PHKG1 | 1.03622777 |
| 17 | FGFR1 | 0.99289781 |
| 18 | TLK1 | 0.84471425 |
| 19 | ADRBK2 | 0.78582506 |
| 20 | SRPK1 | 0.75558881 |
| 21 | ZAK | 0.72820346 |
| 22 | VRK1 | 0.69799371 |
| 23 | INSRR | 0.61926839 |
| 24 | ROCK2 | 0.59750492 |
| 25 | PRKAA1 | 0.58416834 |
| 26 | SRC | 0.57906735 |
| 27 | SYK | 0.56671205 |
| 28 | WNK3 | 0.52329725 |
| 29 | IKBKB | 0.49988548 |
| 30 | GRK1 | 0.49354728 |
| 31 | PRKCQ | 0.48755910 |
| 32 | CCNB1 | 0.48706189 |
| 33 | CHUK | 0.48431188 |
| 34 | PRKACB | 0.47710911 |
| 35 | STK39 | 0.46331375 |
| 36 | PRKACG | 0.44350241 |
| 37 | TEC | 0.42102874 |
| 38 | IKBKE | 0.41910762 |
| 39 | PRKACA | 0.40817069 |
| 40 | ROCK1 | 0.40639780 |
| 41 | ABL1 | 0.40300272 |
| 42 | CAMK2A | 0.39636229 |
| 43 | OXSR1 | 0.35211713 |
| 44 | PIK3CA | 0.34703079 |
| 45 | PIK3CG | 0.34655554 |
| 46 | GRK6 | 0.33690365 |
| 47 | IRAK1 | 0.33103712 |
| 48 | MAP4K2 | 0.32515359 |
| 49 | TSSK6 | 0.32464351 |
| 50 | CAMK2G | 0.31224265 |
| 51 | FRK | 0.30678985 |
| 52 | MAP2K7 | 0.30637787 |
| 53 | MAPK13 | 0.29434777 |
| 54 | GRK7 | 0.28828872 |
| 55 | ABL2 | 0.27129287 |
| 56 | MAP3K4 | 0.25895444 |
| 57 | PLK1 | 0.25741940 |
| 58 | VRK2 | 0.23956547 |
| 59 | EPHA3 | 0.23807793 |
| 60 | PRKCA | 0.23443010 |
| 61 | GSK3B | 0.23364616 |
| 62 | CSNK1A1 | 0.23160793 |
| 63 | PINK1 | 0.22209557 |
| 64 | MAPK14 | 0.21917796 |
| 65 | MAPK15 | 0.21303359 |
| 66 | RPS6KA3 | 0.20911909 |
| 67 | PKN1 | 0.20052930 |
| 68 | ITK | 0.19961101 |
| 69 | LYN | 0.19959928 |
| 70 | CAMK2D | 0.19288626 |
| 71 | MAPK9 | 0.18680731 |
| 72 | PRKCB | 0.18225542 |
| 73 | MARK1 | 0.16941698 |
| 74 | FER | 0.16760718 |
| 75 | PRKD3 | 0.15383574 |
| 76 | RPS6KA5 | 0.14874563 |
| 77 | CDK1 | 0.14619147 |
| 78 | PRKCD | 0.14263933 |
| 79 | TRIM28 | 0.14212391 |
| 80 | PRKG1 | 0.13657341 |
| 81 | ERBB4 | 0.13033807 |
| 82 | WNK1 | 0.12756104 |
| 83 | PRKCE | 0.11855921 |
| 84 | LMTK2 | 0.11724893 |
| 85 | CHEK2 | 0.11240995 |
| 86 | LATS1 | 0.11205576 |
| 87 | EGFR | 0.10645512 |
| 88 | AURKA | 0.10420792 |
| 89 | FYN | 0.10242039 |
| 90 | DYRK3 | 0.10050038 |
| 91 | LCK | 0.09590465 |
| 92 | ADRBK1 | 0.08948480 |
| 93 | IGF1R | 0.08816125 |
| 94 | MAP3K5 | 0.08708984 |
| 95 | PIM1 | 0.08549961 |
| 96 | CSNK1G1 | 0.08285353 |
| 97 | CSNK1G3 | 0.08074749 |
| 98 | CSNK1G2 | 0.07838982 |
| 99 | BTK | 0.07683355 |
| 100 | PRKDC | 0.07468378 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Olfactory transduction_Homo sapiens_hsa04740 | 5.42693929 |
| 2 | Sulfur metabolism_Homo sapiens_hsa00920 | 3.85763824 |
| 3 | Sulfur relay system_Homo sapiens_hsa04122 | 3.50352005 |
| 4 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 3.17403556 |
| 5 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 3.00365629 |
| 6 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 2.81643518 |
| 7 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 2.70504876 |
| 8 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 2.58104493 |
| 9 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 2.43061615 |
| 10 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 2.40580745 |
| 11 | Bile secretion_Homo sapiens_hsa04976 | 2.25089698 |
| 12 | Salivary secretion_Homo sapiens_hsa04970 | 2.13413870 |
| 13 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 2.11340317 |
| 14 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 2.10414791 |
| 15 | Fat digestion and absorption_Homo sapiens_hsa04975 | 2.09630266 |
| 16 | Gastric acid secretion_Homo sapiens_hsa04971 | 2.08881204 |
| 17 | Pancreatic secretion_Homo sapiens_hsa04972 | 2.07643575 |
| 18 | Circadian entrainment_Homo sapiens_hsa04713 | 1.90618491 |
| 19 | Cocaine addiction_Homo sapiens_hsa05030 | 1.89893919 |
| 20 | Taste transduction_Homo sapiens_hsa04742 | 1.83192648 |
| 21 | Insulin secretion_Homo sapiens_hsa04911 | 1.79848765 |
| 22 | Morphine addiction_Homo sapiens_hsa05032 | 1.74567026 |
| 23 | Ether lipid metabolism_Homo sapiens_hsa00565 | 1.74407325 |
| 24 | GABAergic synapse_Homo sapiens_hsa04727 | 1.71947321 |
| 25 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 1.71864386 |
| 26 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 1.68326659 |
| 27 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 1.67519976 |
| 28 | Glutamatergic synapse_Homo sapiens_hsa04724 | 1.56925663 |
| 29 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 1.50821925 |
| 30 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 1.48510197 |
| 31 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 1.44488651 |
| 32 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 1.44085907 |
| 33 | Amphetamine addiction_Homo sapiens_hsa05031 | 1.38889971 |
| 34 | Gap junction_Homo sapiens_hsa04540 | 1.34836042 |
| 35 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 1.26877315 |
| 36 | Circadian rhythm_Homo sapiens_hsa04710 | 1.26548480 |
| 37 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 1.22289510 |
| 38 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 1.20042627 |
| 39 | Melanogenesis_Homo sapiens_hsa04916 | 1.18267768 |
| 40 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 1.15376586 |
| 41 | GnRH signaling pathway_Homo sapiens_hsa04912 | 1.14179264 |
| 42 | Calcium signaling pathway_Homo sapiens_hsa04020 | 1.10035906 |
| 43 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 1.07929563 |
| 44 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 1.07429700 |
| 45 | Cholinergic synapse_Homo sapiens_hsa04725 | 1.06705142 |
| 46 | Alcoholism_Homo sapiens_hsa05034 | 1.01862336 |
| 47 | Platelet activation_Homo sapiens_hsa04611 | 1.00499638 |
| 48 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.95731004 |
| 49 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.90930722 |
| 50 | RNA degradation_Homo sapiens_hsa03018 | 0.89176140 |
| 51 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.82679338 |
| 52 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.77693348 |
| 53 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.77243442 |
| 54 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.75526196 |
| 55 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 0.74435398 |
| 56 | Parkinsons disease_Homo sapiens_hsa05012 | 0.72252238 |
| 57 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.71905311 |
| 58 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 0.61283836 |
| 59 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 0.56672183 |
| 60 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.55894748 |
| 61 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.51695590 |
| 62 | Purine metabolism_Homo sapiens_hsa00230 | 0.51149807 |
| 63 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 0.45585672 |
| 64 | ECM-receptor interaction_Homo sapiens_hsa04512 | 0.44687358 |
| 65 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.40131479 |
| 66 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.39076479 |
| 67 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.38832812 |
| 68 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.37083836 |
| 69 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.33388183 |
| 70 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.29606237 |
| 71 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.26306050 |
| 72 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.25469673 |
| 73 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.20538415 |
| 74 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.19397865 |
| 75 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.16519558 |
| 76 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.15906055 |
| 77 | Phototransduction_Homo sapiens_hsa04744 | 0.15810227 |
| 78 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.15613431 |
| 79 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.14690370 |
| 80 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.14520352 |
| 81 | HTLV-I infection_Homo sapiens_hsa05166 | 0.14124329 |
| 82 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.13127013 |
| 83 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.13037277 |
| 84 | Proteasome_Homo sapiens_hsa03050 | 0.13027172 |
| 85 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.12291006 |
| 86 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.11953968 |
| 87 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.10469765 |
| 88 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.09442705 |
| 89 | Retinol metabolism_Homo sapiens_hsa00830 | 0.09346688 |
| 90 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.09118082 |
| 91 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.08267051 |
| 92 | Nicotine addiction_Homo sapiens_hsa05033 | 0.06855905 |
| 93 | Phagosome_Homo sapiens_hsa04145 | 0.06723657 |
| 94 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.06356527 |
| 95 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.05713243 |
| 96 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.05686742 |
| 97 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.04514984 |
| 98 | Tuberculosis_Homo sapiens_hsa05152 | 0.03431040 |
| 99 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.02001823 |
| 100 | Renin secretion_Homo sapiens_hsa04924 | 0.01749815 |

