

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | activation of protein kinase A activity (GO:0034199) | 9.87121432 |
| 2 | negative regulation of type 2 immune response (GO:0002829) | 9.79763818 |
| 3 | regulation of T-helper 2 cell differentiation (GO:0045628) | 9.75098358 |
| 4 | positive regulation of RNA splicing (GO:0033120) | 9.46692241 |
| 5 | negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515) | 9.44598159 |
| 6 | seminiferous tubule development (GO:0072520) | 9.40878594 |
| 7 | cAMP biosynthetic process (GO:0006171) | 8.67408583 |
| 8 | negative regulation of alpha-beta T cell differentiation (GO:0046639) | 8.46133889 |
| 9 | detection of chemical stimulus involved in sensory perception (GO:0050907) | 8.45977815 |
| 10 | enteric nervous system development (GO:0048484) | 7.71056109 |
| 11 | regulation of protein sumoylation (GO:0033233) | 7.35015546 |
| 12 | synaptic transmission, dopaminergic (GO:0001963) | 7.15135402 |
| 13 | positive regulation of mitochondrial fission (GO:0090141) | 7.03598134 |
| 14 | righting reflex (GO:0060013) | 6.95440663 |
| 15 | dendritic spine morphogenesis (GO:0060997) | 6.94024335 |
| 16 | positive regulation of T-helper 1 type immune response (GO:0002827) | 6.52971331 |
| 17 | heterotypic cell-cell adhesion (GO:0034113) | 6.38688128 |
| 18 | detection of chemical stimulus (GO:0009593) | 6.07713685 |
| 19 | hepatocyte apoptotic process (GO:0097284) | 5.97923773 |
| 20 | icosanoid secretion (GO:0032309) | 5.93817995 |
| 21 | arachidonic acid secretion (GO:0050482) | 5.93817995 |
| 22 | endothelial cell differentiation (GO:0045446) | 5.79292187 |
| 23 | positive regulation of T-helper cell differentiation (GO:0045624) | 5.69021711 |
| 24 | phosphatidylinositol acyl-chain remodeling (GO:0036149) | 5.45303995 |
| 25 | regulation of mitochondrial fission (GO:0090140) | 5.17863235 |
| 26 | drug transmembrane transport (GO:0006855) | 5.16775800 |
| 27 | phosphatidylserine acyl-chain remodeling (GO:0036150) | 5.05207935 |
| 28 | negative regulation of alpha-beta T cell activation (GO:0046636) | 5.04983521 |
| 29 | icosanoid transport (GO:0071715) | 4.88166641 |
| 30 | fatty acid derivative transport (GO:1901571) | 4.88166641 |
| 31 | phosphatidylglycerol acyl-chain remodeling (GO:0036148) | 4.84162988 |
| 32 | neuronal ion channel clustering (GO:0045161) | 4.73242058 |
| 33 | regulation of T-helper 1 type immune response (GO:0002825) | 4.72208315 |
| 34 | neural tube formation (GO:0001841) | 4.70919755 |
| 35 | chemosensory behavior (GO:0007635) | 4.61003705 |
| 36 | energy coupled proton transmembrane transport, against electrochemical gradient (GO:0015988) | 4.52202864 |
| 37 | ATP hydrolysis coupled proton transport (GO:0015991) | 4.52202864 |
| 38 | hyaluronan catabolic process (GO:0030214) | 4.47230725 |
| 39 | embryonic digestive tract morphogenesis (GO:0048557) | 4.46349664 |
| 40 | cilium or flagellum-dependent cell motility (GO:0001539) | 4.44781618 |
| 41 | attachment of spindle microtubules to kinetochore (GO:0008608) | 4.43758870 |
| 42 | nephron epithelium morphogenesis (GO:0072088) | 4.42967319 |
| 43 | nephron tubule morphogenesis (GO:0072078) | 4.42967319 |
| 44 | vocalization behavior (GO:0071625) | 4.42535190 |
| 45 | positive regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043372) | 4.33736506 |
| 46 | positive regulation of membrane potential (GO:0045838) | 4.32217416 |
| 47 | regulation of T-helper cell differentiation (GO:0045622) | 4.31010693 |
| 48 | cyclic purine nucleotide metabolic process (GO:0052652) | 4.29219027 |
| 49 | response to dietary excess (GO:0002021) | 4.28311580 |
| 50 | retina layer formation (GO:0010842) | 4.23427836 |
| 51 | cyclic nucleotide biosynthetic process (GO:0009190) | 4.17221309 |
| 52 | cellular response to glucagon stimulus (GO:0071377) | 4.13212578 |
| 53 | regulation of type 2 immune response (GO:0002828) | 4.03538798 |
| 54 | regulation of cAMP-mediated signaling (GO:0043949) | 4.02685117 |
| 55 | negative regulation of actin filament bundle assembly (GO:0032232) | 4.01975391 |
| 56 | cAMP metabolic process (GO:0046058) | 4.00025109 |
| 57 | water transport (GO:0006833) | 3.95429791 |
| 58 | mitochondrial fusion (GO:0008053) | 3.94621381 |
| 59 | protein localization to synapse (GO:0035418) | 3.92920340 |
| 60 | negative regulation of T cell differentiation (GO:0045581) | 3.91677486 |
| 61 | positive regulation of CD4-positive, alpha-beta T cell activation (GO:2000516) | 3.88627844 |
| 62 | negative regulation of cytosolic calcium ion concentration (GO:0051481) | 3.86338903 |
| 63 | dendritic spine organization (GO:0097061) | 3.85676762 |
| 64 | cellular zinc ion homeostasis (GO:0006882) | 3.76433155 |
| 65 | monoamine transport (GO:0015844) | 3.75130476 |
| 66 | leukotriene biosynthetic process (GO:0019370) | 3.70320394 |
| 67 | drug transport (GO:0015893) | 3.60333631 |
| 68 | cellular response to ATP (GO:0071318) | 3.59098701 |
| 69 | positive regulation of protein targeting to membrane (GO:0090314) | 3.59003940 |
| 70 | phosphatidylethanolamine acyl-chain remodeling (GO:0036152) | 3.57511349 |
| 71 | fluid transport (GO:0042044) | 3.51659012 |
| 72 | pre-miRNA processing (GO:0031054) | 3.47476809 |
| 73 | cytoskeletal anchoring at plasma membrane (GO:0007016) | 3.44122790 |
| 74 | sequestering of metal ion (GO:0051238) | 3.41901324 |
| 75 | regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043370) | 3.39462706 |
| 76 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.38659469 |
| 77 | positive regulation of extrinsic apoptotic signaling pathway via death domain receptors (GO:1902043) | 3.36149102 |
| 78 | sulfur amino acid catabolic process (GO:0000098) | 3.31110351 |
| 79 | neurofilament cytoskeleton organization (GO:0060052) | 3.28084297 |
| 80 | positive regulation of alpha-beta T cell differentiation (GO:0046638) | 3.27651353 |
| 81 | left/right axis specification (GO:0070986) | 3.24243285 |
| 82 | negative regulation of astrocyte differentiation (GO:0048712) | 3.17038359 |
| 83 | positive regulation of excitatory postsynaptic membrane potential (GO:2000463) | 3.16969381 |
| 84 | renal tubule morphogenesis (GO:0061333) | 3.15675944 |
| 85 | negative regulation of homotypic cell-cell adhesion (GO:0034111) | 3.14313067 |
| 86 | reflex (GO:0060004) | 3.14238586 |
| 87 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.13680657 |
| 88 | neuromuscular process controlling posture (GO:0050884) | 3.11852964 |
| 89 | response to glucagon (GO:0033762) | 3.09984381 |
| 90 | phosphatidylcholine acyl-chain remodeling (GO:0036151) | 3.09424143 |
| 91 | adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway (GO:0007193) | 3.03060526 |
| 92 | prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis (GO:006052 | 3.03044820 |
| 93 | negative regulation of hydrogen peroxide-induced cell death (GO:1903206) | 3.02849173 |
| 94 | tooth mineralization (GO:0034505) | 13.9394009 |
| 95 | detection of chemical stimulus involved in sensory perception of smell (GO:0050911) | 13.5445963 |
| 96 | positive regulation of protein sumoylation (GO:0033235) | 11.6801805 |
| 97 | negative regulation of T-helper cell differentiation (GO:0045623) | 11.5666856 |
| 98 | negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371) | 11.5666856 |
| 99 | protein K11-linked deubiquitination (GO:0035871) | 10.3639246 |
| 100 | regulation of T-helper 1 cell differentiation (GO:0045625) | 10.2028854 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 6.30064912 |
| 2 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 5.33467273 |
| 3 | IGF1R_20145208_ChIP-Seq_DFB_Human | 4.92246461 |
| 4 | AR_21572438_ChIP-Seq_LNCaP_Human | 4.66374886 |
| 5 | VDR_22108803_ChIP-Seq_LS180_Human | 4.56241574 |
| 6 | PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse | 3.38256546 |
| 7 | TP53_16413492_ChIP-PET_HCT116_Human | 2.16306670 |
| 8 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 2.10771727 |
| 9 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 10.6102229 |
| 10 | YY1_22570637_ChIP-Seq_MALME-3M_Human | 1.93220552 |
| 11 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.86566718 |
| 12 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.86566718 |
| 13 | ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 1.80631677 |
| 14 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 1.76721738 |
| 15 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.76088515 |
| 16 | NR3C1_23031785_ChIP-Seq_PC12_Mouse | 1.74194701 |
| 17 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.65561523 |
| 18 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.65272342 |
| 19 | GATA1_19941826_ChIP-Seq_K562_Human | 1.62203085 |
| 20 | DROSHA_22980978_ChIP-Seq_HELA_Human | 1.60746962 |
| 21 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.52776715 |
| 22 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.52343287 |
| 23 | EGR1_19032775_ChIP-ChIP_M12_Human | 1.50866721 |
| 24 | SMAD3_21741376_ChIP-Seq_HESCs_Human | 1.47504582 |
| 25 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 1.47455701 |
| 26 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 1.43176003 |
| 27 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.41681096 |
| 28 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.38601507 |
| 29 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 1.35409139 |
| 30 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.33048424 |
| 31 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 1.30019971 |
| 32 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 1.27636282 |
| 33 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 1.27529600 |
| 34 | RXR_22108803_ChIP-Seq_LS180_Human | 1.26428312 |
| 35 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.26054946 |
| 36 | TCF12/HEB_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.24530625 |
| 37 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 1.19957255 |
| 38 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.19734057 |
| 39 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 1.19538635 |
| 40 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.18821627 |
| 41 | SOX2_18555785_Chip-Seq_ESCs_Mouse | 1.14536291 |
| 42 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 1.13123318 |
| 43 | CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse | 1.12826556 |
| 44 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.11596540 |
| 45 | HNFA_21074721_ChIP-Seq_CACO-2_Human | 1.10837809 |
| 46 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 1.10316311 |
| 47 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 1.09878051 |
| 48 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.08818817 |
| 49 | EZH2_22144423_ChIP-Seq_EOC_Human | 1.08460440 |
| 50 | GATA6_21074721_ChIP-Seq_CACO-2_Human | 1.06435471 |
| 51 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 1.05898940 |
| 52 | CMYC_18555785_Chip-Seq_ESCs_Mouse | 1.05872843 |
| 53 | SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 1.05421506 |
| 54 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.04823069 |
| 55 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 1.04539876 |
| 56 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 1.02903463 |
| 57 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 1.02870092 |
| 58 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.02181470 |
| 59 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 1.01839578 |
| 60 | STAT3_23295773_ChIP-Seq_U87_Human | 1.01251674 |
| 61 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 1.01129978 |
| 62 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 0.99559249 |
| 63 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 0.99461742 |
| 64 | SMAD4_21741376_ChIP-Seq_HESCs_Human | 0.98467532 |
| 65 | SUZ12_18555785_Chip-Seq_ESCs_Mouse | 0.98339636 |
| 66 | PHF8_20622853_ChIP-Seq_HELA_Human | 0.98316263 |
| 67 | KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse | 0.97631229 |
| 68 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 0.97351210 |
| 69 | TBL1_22424771_ChIP-Seq_293T_Human | 0.97317482 |
| 70 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 0.97307105 |
| 71 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 0.94399156 |
| 72 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 0.94040161 |
| 73 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 0.93737438 |
| 74 | E2F1_18555785_Chip-Seq_ESCs_Mouse | 0.93346429 |
| 75 | NMYC_18555785_Chip-Seq_ESCs_Mouse | 0.93084078 |
| 76 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 0.92379258 |
| 77 | TRIM28_17542650_ChIP-ChIP_NTERA2_Human | 0.92109414 |
| 78 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.91951804 |
| 79 | DNAJC2_21179169_ChIP-ChIP_NT2_Human | 0.91930668 |
| 80 | KLF4_18555785_Chip-Seq_ESCs_Mouse | 0.91068226 |
| 81 | HIF1A_21447827_ChIP-Seq_MCF-7_Human | 0.90716531 |
| 82 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 0.90705973 |
| 83 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 0.90657725 |
| 84 | CJUN_26792858_Chip-Seq_BT549_Human | 0.88954085 |
| 85 | PCGF4_22325352_ChIP-Seq_293T-Rex_Human | 0.88677999 |
| 86 | NR1I2_20693526_ChIP-Seq_LIVER_Mouse | 0.88564867 |
| 87 | CDX2_21074721_ChIP-Seq_CACO-2_Mouse | 0.88145917 |
| 88 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 0.87052754 |
| 89 | P53_22387025_ChIP-Seq_ESCs_Mouse | 0.86776682 |
| 90 | CBP_20019798_ChIP-Seq_JUKART_Human | 0.86192886 |
| 91 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 0.86192886 |
| 92 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 0.85718069 |
| 93 | SMAD4_21799915_ChIP-Seq_A2780_Human | 0.85367128 |
| 94 | TCF4_22108803_ChIP-Seq_LS180_Human | 0.85111163 |
| 95 | REST_21632747_ChIP-Seq_MESCs_Mouse | 0.84592622 |
| 96 | NANOG_16518401_ChIP-PET_MESCs_Mouse | 0.84150945 |
| 97 | GATA3_20176728_ChIP-ChIP_TSCs_Mouse | 0.84019137 |
| 98 | NANOG_20526341_ChIP-Seq_ESCs_Human | 0.83441466 |
| 99 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 0.81773950 |
| 100 | STAT3_18555785_Chip-Seq_ESCs_Mouse | 0.81288867 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0008961_abnormal_basal_metabolism | 9.36751881 |
| 2 | MP0004130_abnormal_muscle_cell | 4.69850938 |
| 3 | MP0004264_abnormal_extraembryonic_tissu | 3.85791111 |
| 4 | MP0003252_abnormal_bile_duct | 3.63794535 |
| 5 | MP0004133_heterotaxia | 2.77262056 |
| 6 | MP0002928_abnormal_bile_duct | 2.62722318 |
| 7 | MP0006072_abnormal_retinal_apoptosis | 2.50624327 |
| 8 | MP0005448_abnormal_energy_balance | 2.23951310 |
| 9 | MP0005408_hypopigmentation | 2.22308057 |
| 10 | MP0002751_abnormal_autonomic_nervous | 2.21194007 |
| 11 | MP0001270_distended_abdomen | 2.03638631 |
| 12 | MP0005084_abnormal_gallbladder_morpholo | 12.5622489 |
| 13 | MP0004272_abnormal_basement_membrane | 1.90302228 |
| 14 | MP0003329_amyloid_beta_deposits | 1.89366305 |
| 15 | MP0005379_endocrine/exocrine_gland_phen | 1.75227045 |
| 16 | MP0005165_increased_susceptibility_to | 1.58147903 |
| 17 | MP0005220_abnormal_exocrine_pancreas | 1.55505112 |
| 18 | MP0003943_abnormal_hepatobiliary_system | 1.54473203 |
| 19 | MP0009764_decreased_sensitivity_to | 1.50026101 |
| 20 | MP0001529_abnormal_vocalization | 1.49641294 |
| 21 | MP0003718_maternal_effect | 1.47495836 |
| 22 | MP0000604_amyloidosis | 1.20677991 |
| 23 | MP0001905_abnormal_dopamine_level | 1.19615262 |
| 24 | MP0001958_emphysema | 1.16428824 |
| 25 | MP0005646_abnormal_pituitary_gland | 1.12593814 |
| 26 | MP0008875_abnormal_xenobiotic_pharmacok | 1.09307469 |
| 27 | MP0002909_abnormal_adrenal_gland | 1.07005084 |
| 28 | MP0002572_abnormal_emotion/affect_behav | 1.04487610 |
| 29 | MP0001800_abnormal_humoral_immune | 0.98148198 |
| 30 | MP0000470_abnormal_stomach_morphology | 0.97844720 |
| 31 | MP0001944_abnormal_pancreas_morphology | 0.95996759 |
| 32 | MP0003638_abnormal_response/metabolism_ | 0.94541629 |
| 33 | MP0008469_abnormal_protein_level | 0.94275906 |
| 34 | MP0000465_gastrointestinal_hemorrhage | 0.92016945 |
| 35 | MP0008569_lethality_at_weaning | 0.90237661 |
| 36 | MP0001790_abnormal_immune_system | 0.88567808 |
| 37 | MP0005387_immune_system_phenotype | 0.88567808 |
| 38 | MP0003121_genomic_imprinting | 0.87667207 |
| 39 | MP0002405_respiratory_system_inflammati | 0.84997417 |
| 40 | MP0002693_abnormal_pancreas_physiology | 0.84138013 |
| 41 | MP0000371_diluted_coat_color | 0.83693837 |
| 42 | MP0001986_abnormal_taste_sensitivity | 0.83044260 |
| 43 | MP0004019_abnormal_vitamin_homeostasis | 0.81880357 |
| 44 | MP0005253_abnormal_eye_physiology | 0.78198498 |
| 45 | MP0003866_abnormal_defecation | 0.75517750 |
| 46 | MP0001915_intracranial_hemorrhage | 0.73710300 |
| 47 | MP0000609_abnormal_liver_physiology | 0.71197493 |
| 48 | MP0001533_abnormal_skeleton_physiology | 0.69797370 |
| 49 | MP0000703_abnormal_thymus_morphology | 0.67847213 |
| 50 | MP0005164_abnormal_response_to | 0.66382087 |
| 51 | MP0002078_abnormal_glucose_homeostasis | 0.65106319 |
| 52 | MP0002136_abnormal_kidney_physiology | 0.64371765 |
| 53 | MP0001835_abnormal_antigen_presentation | 0.61952263 |
| 54 | MP0002822_catalepsy | 0.61601054 |
| 55 | MP0003953_abnormal_hormone_level | 0.60555404 |
| 56 | MP0001845_abnormal_inflammatory_respons | 0.60478637 |
| 57 | MP0002098_abnormal_vibrissa_morphology | 0.58714702 |
| 58 | MP0002998_abnormal_bone_remodeling | 0.56862956 |
| 59 | MP0004947_skin_inflammation | 0.55868301 |
| 60 | MP0005551_abnormal_eye_electrophysiolog | 0.53536627 |
| 61 | MP0005671_abnormal_response_to | 0.52792554 |
| 62 | MP0002722_abnormal_immune_system | 0.52178276 |
| 63 | MP0001851_eye_inflammation | 0.49550914 |
| 64 | MP0002452_abnormal_antigen_presenting | 0.49168371 |
| 65 | MP0009642_abnormal_blood_homeostasis | 0.48648879 |
| 66 | MP0005000_abnormal_immune_tolerance | 0.48262484 |
| 67 | MP0002723_abnormal_immune_serum | 0.47306270 |
| 68 | MP0001501_abnormal_sleep_pattern | 0.45778844 |
| 69 | MP0002420_abnormal_adaptive_immunity | 0.45611552 |
| 70 | MP0001299_abnormal_eye_distance/ | 0.45292208 |
| 71 | MP0002429_abnormal_blood_cell | 0.45224992 |
| 72 | MP0003195_calcinosis | 0.44940901 |
| 73 | MP0001819_abnormal_immune_cell | 0.44752060 |
| 74 | MP0002419_abnormal_innate_immunity | 0.43850341 |
| 75 | MP0000716_abnormal_immune_system | 0.41820472 |
| 76 | MP0002736_abnormal_nociception_after | 0.41389877 |
| 77 | MP0000920_abnormal_myelination | 0.41205889 |
| 78 | MP0009785_altered_susceptibility_to | 0.39532776 |
| 79 | MP0005645_abnormal_hypothalamus_physiol | 0.39234185 |
| 80 | MP0002102_abnormal_ear_morphology | 0.38811594 |
| 81 | MP0002735_abnormal_chemical_nociception | 0.37739645 |
| 82 | MP0002398_abnormal_bone_marrow | 0.37446588 |
| 83 | MP0002229_neurodegeneration | 0.37082882 |
| 84 | MP0005636_abnormal_mineral_homeostasis | 0.37055549 |
| 85 | MP0005395_other_phenotype | 0.36291114 |
| 86 | MP0000477_abnormal_intestine_morphology | 0.36112766 |
| 87 | MP0000598_abnormal_liver_morphology | 0.36025519 |
| 88 | MP0003436_decreased_susceptibility_to | 0.35342277 |
| 89 | MP0005334_abnormal_fat_pad | 0.34862857 |
| 90 | MP0002882_abnormal_neuron_morphology | 0.34401768 |
| 91 | MP0009931_abnormal_skin_appearance | 0.34128659 |
| 92 | MP0005390_skeleton_phenotype | 0.33674442 |
| 93 | MP0004484_altered_response_of | 0.33002156 |
| 94 | MP0000689_abnormal_spleen_morphology | 0.31614495 |
| 95 | MP0001968_abnormal_touch/_nociception | 0.30925809 |
| 96 | MP0002837_dystrophic_cardiac_calcinosis | 0.29612027 |
| 97 | MP0005319_abnormal_enzyme/_coenzyme | 0.29054452 |
| 98 | MP0005423_abnormal_somatic_nervous | 0.28712198 |
| 99 | MP0005365_abnormal_bile_salt | 0.28404619 |
| 100 | MP0002066_abnormal_motor_capabilities/c | 0.28082102 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Abnormality of calcium-phosphate metabolism (HP:0100530) | 9.89532402 |
| 2 | Abnormality of dental color (HP:0011073) | 8.38518309 |
| 3 | Abnormality of renal resorption (HP:0011038) | 8.27465199 |
| 4 | Polyuria (HP:0000103) | 7.55436579 |
| 5 | Osteomalacia (HP:0002749) | 7.39450797 |
| 6 | Abnormality of the dental pulp (HP:0006479) | 7.21318351 |
| 7 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 6.64935533 |
| 8 | Abnormal urine output (HP:0012590) | 6.43971052 |
| 9 | Abnormality of renal excretion (HP:0011036) | 5.59858272 |
| 10 | Round ear (HP:0100830) | 5.44193399 |
| 11 | Chronic bronchitis (HP:0004469) | 4.76863666 |
| 12 | Autoimmune thrombocytopenia (HP:0001973) | 4.55740843 |
| 13 | Volvulus (HP:0002580) | 4.27472586 |
| 14 | IgM deficiency (HP:0002850) | 4.27446229 |
| 15 | Molar tooth sign on MRI (HP:0002419) | 4.11656109 |
| 16 | Abnormality of midbrain morphology (HP:0002418) | 4.11656109 |
| 17 | Toxemia of pregnancy (HP:0100603) | 4.05352215 |
| 18 | Lip pit (HP:0100267) | 3.80977981 |
| 19 | Nephrocalcinosis (HP:0000121) | 3.71893946 |
| 20 | Esophageal varix (HP:0002040) | 3.65155297 |
| 21 | Tachypnea (HP:0002789) | 3.33292648 |
| 22 | Abnormal respiratory motile cilium physiology (HP:0012261) | 3.31589748 |
| 23 | Depressed nasal tip (HP:0000437) | 3.26425750 |
| 24 | Rhinitis (HP:0012384) | 3.25542902 |
| 25 | Panhypogammaglobulinemia (HP:0003139) | 3.25469376 |
| 26 | Lipoatrophy (HP:0100578) | 3.24255973 |
| 27 | Large earlobe (HP:0009748) | 3.18992872 |
| 28 | Drooling (HP:0002307) | 3.13119587 |
| 29 | Hyperphosphaturia (HP:0003109) | 3.12600423 |
| 30 | Intestinal fistula (HP:0100819) | 3.02076648 |
| 31 | Nephronophthisis (HP:0000090) | 3.01443039 |
| 32 | Sparse lateral eyebrow (HP:0005338) | 2.99621335 |
| 33 | Excessive salivation (HP:0003781) | 2.98850766 |
| 34 | Recurrent cutaneous fungal infections (HP:0011370) | 2.89737792 |
| 35 | Chronic mucocutaneous candidiasis (HP:0002728) | 2.89737792 |
| 36 | Hypoparathyroidism (HP:0000829) | 2.87463260 |
| 37 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 2.86267107 |
| 38 | Ureteral stenosis (HP:0000071) | 2.71544723 |
| 39 | Thick eyebrow (HP:0000574) | 2.68421143 |
| 40 | Personality changes (HP:0000751) | 2.62059132 |
| 41 | Abnormality of urine glucose concentration (HP:0011016) | 2.60761724 |
| 42 | Glycosuria (HP:0003076) | 2.60761724 |
| 43 | Abnormal urine phosphate concentration (HP:0012599) | 2.60505931 |
| 44 | Inability to walk (HP:0002540) | 2.49880730 |
| 45 | Ureteral obstruction (HP:0006000) | 2.49498279 |
| 46 | Hepatitis (HP:0012115) | 2.44783391 |
| 47 | Petechiae (HP:0000967) | 2.43979050 |
| 48 | Dilated cardiomyopathy (HP:0001644) | 2.39197053 |
| 49 | Abnormality of transition element cation homeostasis (HP:0011030) | 2.32949372 |
| 50 | Nephropathy (HP:0000112) | 2.32010390 |
| 51 | Gingival overgrowth (HP:0000212) | 2.28952533 |
| 52 | Abnormality of the renal medulla (HP:0100957) | 2.27004252 |
| 53 | Striae distensae (HP:0001065) | 2.22760259 |
| 54 | Short 5th finger (HP:0009237) | 2.17903009 |
| 55 | Agammaglobulinemia (HP:0004432) | 2.16208404 |
| 56 | Colitis (HP:0002583) | 2.15760304 |
| 57 | Hypercalciuria (HP:0002150) | 2.14606361 |
| 58 | Decreased muscle mass (HP:0003199) | 2.14193654 |
| 59 | Bronchitis (HP:0012387) | 2.14165395 |
| 60 | Aplasia/Hypoplasia of the 5th finger (HP:0006262) | 2.07816614 |
| 61 | Recurrent otitis media (HP:0000403) | 2.05416819 |
| 62 | Sudden cardiac death (HP:0001645) | 2.05270893 |
| 63 | Overgrowth (HP:0001548) | 11.8640295 |
| 64 | Amelogenesis imperfecta (HP:0000705) | 11.3234204 |
| 65 | Abnormality of salivation (HP:0100755) | 1.97266761 |
| 66 | Abnormality of the fingertips (HP:0001211) | 1.94493023 |
| 67 | Renal tubular dysfunction (HP:0000124) | 1.93797645 |
| 68 | Chorioretinal coloboma (HP:0000567) | 1.91068204 |
| 69 | Periauricular skin pits (HP:0100277) | 1.87444332 |
| 70 | Preauricular pit (HP:0004467) | 1.87444332 |
| 71 | Prominent supraorbital ridges (HP:0000336) | 1.87195908 |
| 72 | Polyneuropathy (HP:0001271) | 1.85366785 |
| 73 | Delayed eruption of teeth (HP:0000684) | 1.84600463 |
| 74 | Chondrocalcinosis (HP:0000934) | 1.75931478 |
| 75 | Anal stenosis (HP:0002025) | 1.75243645 |
| 76 | Abnormality of Sharpey fibers (HP:0100685) | 1.72573966 |
| 77 | Stage 5 chronic kidney disease (HP:0003774) | 1.72312519 |
| 78 | Abnormality of small intestinal villus morphology (HP:0011472) | 1.66279811 |
| 79 | Villous atrophy (HP:0011473) | 1.66279811 |
| 80 | Ectropion (HP:0000656) | 1.66218066 |
| 81 | Ectopic kidney (HP:0000086) | 1.65391290 |
| 82 | Small hand (HP:0200055) | 1.64207818 |
| 83 | Encephalitis (HP:0002383) | 1.62333020 |
| 84 | Preauricular skin tag (HP:0000384) | 1.61858280 |
| 85 | Oculomotor apraxia (HP:0000657) | 1.59455781 |
| 86 | Bronchiectasis (HP:0002110) | 1.58173801 |
| 87 | Torticollis (HP:0000473) | 1.56076217 |
| 88 | Palmoplantar keratoderma (HP:0000982) | 1.55187205 |
| 89 | Truncal ataxia (HP:0002078) | 1.54743863 |
| 90 | Prenatal maternal abnormality (HP:0002686) | 1.42352232 |
| 91 | Limited elbow extension (HP:0001377) | 1.41996030 |
| 92 | Delayed gross motor development (HP:0002194) | 1.41114761 |
| 93 | Highly arched eyebrow (HP:0002553) | 1.40656704 |
| 94 | Blepharitis (HP:0000498) | 1.40121503 |
| 95 | Inflammation of the large intestine (HP:0002037) | 1.39286270 |
| 96 | Abnormality of T cell physiology (HP:0011840) | 1.36053070 |
| 97 | Severe muscular hypotonia (HP:0006829) | 1.35207574 |
| 98 | Skin tags (HP:0010609) | 1.29897006 |
| 99 | Autoimmune hemolytic anemia (HP:0001890) | 1.29645132 |
| 100 | Viral hepatitis (HP:0006562) | 1.28108484 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MAP4K1 | 5.63209833 |
| 2 | STK3 | 4.02849701 |
| 3 | BLK | 4.01450962 |
| 4 | RIPK4 | 2.90410529 |
| 5 | NTRK2 | 13.9601268 |
| 6 | CDC42BPA | 1.94785267 |
| 7 | BMPR2 | 1.92162258 |
| 8 | HIPK2 | 1.13280998 |
| 9 | TXK | 1.03405367 |
| 10 | MAP4K2 | 1.02892304 |
| 11 | TAOK3 | 0.95084478 |
| 12 | FGFR1 | 0.86790905 |
| 13 | ROCK2 | 0.72102724 |
| 14 | GRK1 | 0.70196682 |
| 15 | SYK | 0.69899598 |
| 16 | WNK3 | 0.68832923 |
| 17 | PRKCQ | 0.63543921 |
| 18 | INSRR | 0.62955062 |
| 19 | OBSCN | 0.62041241 |
| 20 | ADRBK2 | 0.61308323 |
| 21 | SRC | 0.59872035 |
| 22 | GRK7 | 0.57832559 |
| 23 | WNK4 | 0.57329053 |
| 24 | SRPK1 | 0.55917734 |
| 25 | PIK3CG | 0.55865322 |
| 26 | PRKAA1 | 0.53458548 |
| 27 | ROCK1 | 0.53240850 |
| 28 | OXSR1 | 0.52956722 |
| 29 | TLK1 | 0.52834616 |
| 30 | MUSK | 0.49813159 |
| 31 | ABL1 | 0.45038331 |
| 32 | MAP2K6 | 0.44899462 |
| 33 | PRKACG | 0.44536280 |
| 34 | TIE1 | 0.44142584 |
| 35 | PRKACA | 0.40269393 |
| 36 | PRKACB | 0.39842301 |
| 37 | CAMK2A | 0.39092551 |
| 38 | NEK1 | 0.38217990 |
| 39 | PHKG1 | 0.35425471 |
| 40 | PHKG2 | 0.35425471 |
| 41 | ZAK | 0.33342249 |
| 42 | MAPK15 | 0.32887724 |
| 43 | KIT | 0.32075416 |
| 44 | BCKDK | 0.30667157 |
| 45 | ERBB4 | 0.28730799 |
| 46 | MAP2K7 | 0.28675924 |
| 47 | PLK1 | 0.28172432 |
| 48 | LYN | 0.27644938 |
| 49 | EPHA4 | 0.26826775 |
| 50 | STK39 | 0.26585821 |
| 51 | PRKCA | 0.25912385 |
| 52 | MARK1 | 0.24904662 |
| 53 | MAP3K4 | 0.24659057 |
| 54 | KDR | 0.24443382 |
| 55 | MATK | 0.23996932 |
| 56 | FRK | 0.23136855 |
| 57 | IRAK4 | 0.22566470 |
| 58 | ITK | 0.21680561 |
| 59 | PRKCB | 0.21607790 |
| 60 | CSNK1A1 | 0.21071161 |
| 61 | MAPK14 | 0.20760862 |
| 62 | LCK | 0.19325590 |
| 63 | FYN | 0.18727087 |
| 64 | GSK3B | 0.18617648 |
| 65 | RPS6KA3 | 0.18506677 |
| 66 | EPHA3 | 0.17584100 |
| 67 | TNK2 | 0.16151626 |
| 68 | PRKCG | 0.15279567 |
| 69 | VRK1 | 0.15254429 |
| 70 | GRK5 | 0.13908002 |
| 71 | PRKCD | 0.12679319 |
| 72 | CHUK | 0.12541593 |
| 73 | PKN1 | 0.12124249 |
| 74 | PINK1 | 0.12116613 |
| 75 | LMTK2 | 0.11958912 |
| 76 | IGF1R | 0.11858246 |
| 77 | MAPK9 | 0.11746382 |
| 78 | ACVR1B | 0.11186999 |
| 79 | TEC | 0.10890128 |
| 80 | CDK1 | 0.10745531 |
| 81 | IKBKE | 0.10622919 |
| 82 | CASK | 0.10562319 |
| 83 | MAPK13 | 0.10374791 |
| 84 | BTK | 0.10188216 |
| 85 | RPS6KA5 | 0.09971353 |
| 86 | CAMK2G | 0.09680344 |
| 87 | PRKG1 | 0.09466935 |
| 88 | PRKCE | 0.09166302 |
| 89 | ADRBK1 | 0.09049637 |
| 90 | EGFR | 0.08474884 |
| 91 | TGFBR2 | 0.08241317 |
| 92 | CAMK2D | 0.07920047 |
| 93 | PLK4 | 0.07647906 |
| 94 | CSF1R | 0.07272093 |
| 95 | PRKDC | 0.07002457 |
| 96 | MYLK | 0.06532469 |
| 97 | PRKG2 | 0.06445621 |
| 98 | CDK3 | 0.06362756 |
| 99 | EPHA2 | 0.06002068 |
| 100 | CAMK2B | 0.05921259 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Olfactory transduction_Homo sapiens_hsa04740 | 5.28740981 |
| 2 | Sulfur metabolism_Homo sapiens_hsa00920 | 3.90023787 |
| 3 | Sulfur relay system_Homo sapiens_hsa04122 | 3.74348697 |
| 4 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 3.31390420 |
| 5 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 3.26574029 |
| 6 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 3.00938656 |
| 7 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 2.68957247 |
| 8 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 2.60096353 |
| 9 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 2.58481210 |
| 10 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 2.38293712 |
| 11 | Bile secretion_Homo sapiens_hsa04976 | 2.28020980 |
| 12 | Pancreatic secretion_Homo sapiens_hsa04972 | 2.18841217 |
| 13 | Fat digestion and absorption_Homo sapiens_hsa04975 | 2.18358650 |
| 14 | Salivary secretion_Homo sapiens_hsa04970 | 2.17128302 |
| 15 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 2.12562733 |
| 16 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 2.05547306 |
| 17 | Gastric acid secretion_Homo sapiens_hsa04971 | 2.04024484 |
| 18 | Cocaine addiction_Homo sapiens_hsa05030 | 1.99402804 |
| 19 | Circadian entrainment_Homo sapiens_hsa04713 | 1.86984261 |
| 20 | Insulin secretion_Homo sapiens_hsa04911 | 1.84384037 |
| 21 | Ether lipid metabolism_Homo sapiens_hsa00565 | 1.75505961 |
| 22 | Taste transduction_Homo sapiens_hsa04742 | 1.74809954 |
| 23 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 1.74175029 |
| 24 | Glutamatergic synapse_Homo sapiens_hsa04724 | 1.71310461 |
| 25 | GABAergic synapse_Homo sapiens_hsa04727 | 1.71294480 |
| 26 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 1.69816331 |
| 27 | Morphine addiction_Homo sapiens_hsa05032 | 1.69601876 |
| 28 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 1.55195336 |
| 29 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 1.47159027 |
| 30 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 1.46419269 |
| 31 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 1.44526054 |
| 32 | Amphetamine addiction_Homo sapiens_hsa05031 | 1.43161417 |
| 33 | Gap junction_Homo sapiens_hsa04540 | 1.39446695 |
| 34 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 1.39219623 |
| 35 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 1.35806450 |
| 36 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 1.34165407 |
| 37 | Melanogenesis_Homo sapiens_hsa04916 | 1.20600900 |
| 38 | GnRH signaling pathway_Homo sapiens_hsa04912 | 1.20500089 |
| 39 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 1.07386658 |
| 40 | Cholinergic synapse_Homo sapiens_hsa04725 | 1.06851281 |
| 41 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 1.05528362 |
| 42 | Platelet activation_Homo sapiens_hsa04611 | 1.05105130 |
| 43 | Calcium signaling pathway_Homo sapiens_hsa04020 | 1.02854621 |
| 44 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 1.02082532 |
| 45 | Circadian rhythm_Homo sapiens_hsa04710 | 0.97839707 |
| 46 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.89769760 |
| 47 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.87657202 |
| 48 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.82478851 |
| 49 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.78928791 |
| 50 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.78312015 |
| 51 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.77459716 |
| 52 | RNA degradation_Homo sapiens_hsa03018 | 0.72494092 |
| 53 | Parkinsons disease_Homo sapiens_hsa05012 | 0.69003894 |
| 54 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 0.68920829 |
| 55 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.66108858 |
| 56 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.62857911 |
| 57 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 0.58535046 |
| 58 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 0.55594759 |
| 59 | ECM-receptor interaction_Homo sapiens_hsa04512 | 0.55404669 |
| 60 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.43353560 |
| 61 | Asthma_Homo sapiens_hsa05310 | 0.41761571 |
| 62 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.40859685 |
| 63 | Alcoholism_Homo sapiens_hsa05034 | 0.38214342 |
| 64 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.37380970 |
| 65 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.37366271 |
| 66 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.35742866 |
| 67 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.35642372 |
| 68 | Purine metabolism_Homo sapiens_hsa00230 | 0.34478763 |
| 69 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.32827926 |
| 70 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.31768572 |
| 71 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.30589622 |
| 72 | Allograft rejection_Homo sapiens_hsa05330 | 0.30563013 |
| 73 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.30045931 |
| 74 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 0.29013766 |
| 75 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.26648885 |
| 76 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.26584158 |
| 77 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.26094082 |
| 78 | Retinol metabolism_Homo sapiens_hsa00830 | 0.22849513 |
| 79 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.17484992 |
| 80 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.17061757 |
| 81 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.16071201 |
| 82 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.15376735 |
| 83 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.15196093 |
| 84 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.14692739 |
| 85 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.13962031 |
| 86 | Nicotine addiction_Homo sapiens_hsa05033 | 0.13064813 |
| 87 | Tuberculosis_Homo sapiens_hsa05152 | 0.12902053 |
| 88 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.12264527 |
| 89 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.12119685 |
| 90 | Prion diseases_Homo sapiens_hsa05020 | 0.11357675 |
| 91 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.11202509 |
| 92 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.11021306 |
| 93 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.10397252 |
| 94 | Phagosome_Homo sapiens_hsa04145 | 0.09727034 |
| 95 | Leishmaniasis_Homo sapiens_hsa05140 | 0.09651053 |
| 96 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.09608796 |
| 97 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.08730416 |
| 98 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.07420693 |
| 99 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.06499991 |
| 100 | HTLV-I infection_Homo sapiens_hsa05166 | 0.06154816 |

